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Ileal pouch anal anastomosis

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https://www.readbyqxmd.com/read/29882252/the-impact-of-ileal-pouch-anal-anastomosis-on-graft-survival-following-liver-transplantation-for-primary-sclerosing-cholangitis
#1
P J Trivedi, J Reece, R W Laing, E Slaney, R Cooney, B K Gunson, S K Kamarajah, T Pinkney, F Thompson, P Muiesan, A Schlegel, G M Hirschfield, T Iqbal, J Ferguson
BACKGROUND: Liver transplantation is the only life-extending intervention for primary sclerosing cholangitis (PSC). Given the co-existence with colitis, patients may also require colectomy; a factor potentially conferring improved post-transplant outcomes. AIM: To determine the impact of restorative surgery via ileal pouch-anal anastomosis (IPAA) vs retaining an end ileostomy on liver-related outcomes post-transplantation. METHODS: Graft survival was evaluated across a prospectively accrued transplant database, stratified according to colectomy status and type...
June 8, 2018: Alimentary Pharmacology & Therapeutics
https://www.readbyqxmd.com/read/29805360/neoterminal-ileal-polyposis-and-ulceration-after-restorative-proctocolectomy-with-a-current-review-of-the-literature
#2
Venkata Subhash Gorrepati, Negar Rassaei, Kofi Clarke
After ileal pouch anal anastomosis, one of the frequently encountered complications is polyposis of the pouch. We describe a case of proximal neoterminal ileal polyposis associated with deep ulceration suggestive of Crohn's disease and review the available literature. A 36-year-old male presented with resistant pouchitis 11 years after surgery for ulcerative colitis. With all-negative initial workup, pouchoscopy showed multiple deep ulcers in the proximal ileum with some polyps. Biopsy of polyps showed inflammatory polyps with negative immunohistological staining for IgG pouchitis...
January 2018: Case Reports in Gastroenterology
https://www.readbyqxmd.com/read/29803758/increase-in-chromogranin-a-and-serotonin-positive-cells-in-pouch-mucosa-of-patients-with-ulcerative-colitis-undergoing-proctocolectomy
#3
Paolo Giuffrida, Alessandro Vanoli, Elena Biletta, Catherine Klersy, Gaetano Bergamaschi, Gianluca M Sampietro, Sandro Ardizzone, Ombretta Luinetti, Michele Martino, Marco Vincenzo Lenti, Nicola Aronico, Marco Curti, Rachele Manca, Paolo Fociani, Marta Truffi, Fabio Corsi, Gino Roberto Corazza, Antonio Di Sabatino
BACKGROUND: Inflammatory bowel disease (IBD) is associated with neuroendocrine cell hyperplasia. AIMS: We investigated neuroendocrine cells in J-pouches of patients with ulcerative colitis undergoing restorative proctocolectomy and ileal pouch-anal anastomosis. METHODS: Sections from pouch biopsies of 17 patients and ileal biopsies of 17 active IBD patients and 16 controls were processed by immunohistochemistry for chromogranin A (CgA) and serotonin...
April 28, 2018: Digestive and Liver Disease
https://www.readbyqxmd.com/read/29802852/efficacy-and-safety-of-curcumin-in-treatment-of-intestinal-adenomas-in-patients-with-familial-adenomatous-polyposis
#4
Marcia Cruz-Correa, Linda M Hylind, Jessica Hernandez Marrero, Marianna L Zahurak, Tracy Murray-Stewart, Robert A Casero, Elizabeth A Montgomery, Christine Iacobuzio-Donahue, Lodewijk A Brosens, G Johan Offerhaus, Asad Umar, Luz M Rodriguez, Francis M Giardiello
BACKGROUND & AIMS: Familial adenomatous polyposis is an autosomal dominant disorder characterized by development of hundreds of colorectal adenomas and eventually colorectal cancer. Oral administration of the spice curcumin has been followed by regression of polyps in patients with this disorder. We performed a double-blind, randomized trial to determine the safety and efficacy of curcumin in patients with familial adenomatous polyposis. METHODS: Our study comprised 44 patients with familial adenomatous polyposis (18 to 85 years old) who had either not undergone colectomy or had undergone colectomy with ileorectal anastomosis or ileal anal pouches and had 5 or more intestinal adenomatous polyps, enrolled in Puerto Rico or the United States from September 2011 through November 2016...
May 23, 2018: Gastroenterology
https://www.readbyqxmd.com/read/29788269/smoking-and-the-risk-of-pouchitis-in-ulcerative-colitis-patients-with-ileal-pouch-anal-anastomosis
#5
Venkata Subhash Gorrepati, August Stuart, Susan Deiling, Walter Koltun, Andrew Tinsley, Emmanuelle D Williams, Matthew D Coates
Background: Ulcerative colitis (UC) patients who undergo proctocolectomy with ileal pouch-anal anastomosis (IPAA) may develop pouchitis, a poorly understood inflammatory condition. There is controversy over whether tobacco use can protect against pouchitis. We undertook this investigation to further evaluate whether smoking reduces the risk of developing pouchitis and to determine whether other previously associated clinical factors change the risk for pouchitis. Methods: We performed a retrospective analysis using a consented inflammatory bowel disease (IBD) natural history registry between the years 1995-2015 from a single tertiary care referral center...
May 17, 2018: Inflammatory Bowel Diseases
https://www.readbyqxmd.com/read/29787362/j-pouch-imaging-findings-surgical-variations-natural-history-and-common-complications
#6
Joshua D Reber, John M Barlow, Amy L Lightner, Shannon P Sheedy, David H Bruining, Christine O Menias, Joel G Fletcher
Ileal pouch-anal anastomosis, or J pouch, surgery has become the procedure of choice for treatment of medically refractory ulcerative colitis and familial adenomatous polyposis. Overall, this operation is associated with a low rate of postoperative morbidity and good long-term function. However, when complications develop, there is a heavy reliance on imaging to facilitate an accurate diagnosis. Reported postoperative complication rates range from 5% to 35%. Complications generally can be categorized as structural, inflammatory, or neoplastic conditions...
May 25, 2018: Radiographics: a Review Publication of the Radiological Society of North America, Inc
https://www.readbyqxmd.com/read/29785696/case-matched-comparison-of-long-term-functional-and-quality-of-life-outcomes-following-laparoscopic-versus-open-ileal-pouch-anal-anastomosis
#7
Olga A Lavryk, Luca Stocchi, Jean H Ashburn, Meagan Costedio, Emre Gorgun, Tracy L Hull, Hermann Kessler, Conor P Delaney
BACKGROUND: Laparoscopic ileal pouch-anal anastomosis (IPAA) is associated with recovery benefits when compared with open IPAA. There is limited data on long-term quality of life and functional outcomes, which this study aimed to assess. METHODS: An IRB-approved, prospectively maintained database was queried to identify patients undergoing laparoscopic IPAA (L), case-matched with open IPAA (O) based on age ± 5 years, gender, body mass index (BMI) ± 5 kg/m2 , diagnosis, date of surgery ± 3 years, stapled/handsewn anastomosis, omission of diverting loop ileostomy and length of follow-up ± 3 years...
May 21, 2018: World Journal of Surgery
https://www.readbyqxmd.com/read/29780596/value-of-routine-stool-testing-for-pathogenic-bacteria-in-the-evaluation-of-symptomatic-patients-with-ileal-pouches
#8
Amandeep Singh, Jean Ashburn, Gursimran Kochhar, Rocio Lopez, Tracy L Hull, Bo Shen
Background: In symptomatic patients with an ileal pouch, stool studies are often sent to diagnose enteric pathogens. Aim of this study is to find the value of routine stool studies in the evaluation of symptomatic patients and the clinical implications of such pathogens in patients with ileal pouches. Methods: Consecutive ileal pouch-anal anastomosis (IPAA) patients who had stool tests out of a 2283-case registry from 2002 to 2015 were included in the study. Patients with positive stool cultures were compared with controls (symptomatic without positive stool culture) in a 1:4 ratio...
May 2018: Gastroenterology Report
https://www.readbyqxmd.com/read/29742859/small-bowel-obstruction-after-ileal-pouch-anal-anastomosis-with-a-loop-ileostomy-in-patients-with-ulcerative-colitis
#9
Hitoshi Kameyama, Yoshifumi Hashimoto, Yoshifumi Shimada, Saki Yamada, Ryoma Yagi, Yosuke Tajima, Takuma Okamura, Masato Nakano, Kohei Miura, Masayuki Nagahashi, Jun Sakata, Takashi Kobayashi, Shin-Ichi Kosugi, Toshifumi Wakai
PURPOSE: Small bowel obstruction (SBO) remains a common complication after pelvic or abdominal surgery. However, the risk factors for SBO in ulcerative colitis (UC) surgery are not well known. The aim of the present study was to clarify the risk factors associated with SBO after ileal pouch-anal anastomosis (IPAA) with a loop ileostomy for patients with UC. METHODS: The medical records of 96 patients who underwent IPAA for UC between 1999 and 2011 were reviewed...
April 2018: Annals of Coloproctology
https://www.readbyqxmd.com/read/29742857/a-common-complication-after-an-ileal-pouch-anal-anastomosis-with-a-loop-ileostomy-in-patients-with-ulcerative-colitis-small-bowel-obstruction
#10
Chang-Nam Kim
No abstract text is available yet for this article.
April 2018: Annals of Coloproctology
https://www.readbyqxmd.com/read/29718244/burden-of-ulcerative-colitis-on-functioning-and-well-being-a-systematic-literature-review-of-the-sf-36%C3%A2-health-survey
#11
Aaron Yarlas, David T Rubin, Julian Panés, James O Lindsay, Séverine Vermeire, Martha Bayliss, Joseph C Cappelleri, Stephen Maher, Andrew G Bushmakin, Lea Ann Chen, Marco DiBonaventura
Background and Aims: This review is the first to evaluate the burden of ulcerative colitis [UC] on patients' quality of life by synthesizing data from studies comparing scores from the SF-36® Health Survey, a generic measure assessing eight quality-of-life domains, between UC patients and matched reference samples. Methods: A systematic review of the published literature identified articles reporting SF-36 domains or physical and mental component summary scores [PCS, MCS] from UC and reference samples...
April 27, 2018: Journal of Crohn's & Colitis
https://www.readbyqxmd.com/read/29718243/the-impact-of-age-at-time-of-ileal-pouch-anal-anastomosis-on-short-and-long-term-outcomes-in-adults
#12
Nicholas P McKenna, Kellie L Mathis, John H Pemberton, Amy L Lightner
Background: There is limited knowledge on ileal pouch anal anastomosis (IPAA) function when performed on patients older than age 50 years. The aim of this study was to determine if surgery on those older than age 50 years impacts short-term complications or long-term function. Methods: A retrospective review of all patients undergoing IPAA for chronic ulcerative colitis at a single tertiary referral center between 2002 and 2013 was conducted. Short-term postoperative complications and long-term function and quality of life were analyzed according to age at pouch formation (age >50 vs age ≤50 years)...
April 26, 2018: Inflammatory Bowel Diseases
https://www.readbyqxmd.com/read/29697787/delayed-ileal-pouch-anal-anastomosis-has-a-lower-30-day-adverse-event-rate-analysis-from-the-national-surgical-quality-improvement-program
#13
Bharati Kochar, Edward L Barnes, Anne F Peery, Katherine S Cools, Joseph Galanko, Mark Koruda, Hans H Herfarth
Background: Ulcerative colitis (UC) patients requiring colectomy often have a staged ileal pouch anal anastomosis (IPAA). There are no prospective data comparing timing of pouch creation. We aimed to compare 30-day adverse event rates for pouch creation at the time of colectomy (PTC) with delayed pouch creation (DPC). Methods: Using prospectively collected data from 2011-2015 through the National Surgical Quality Improvement Program, we conducted a cohort study including subjects aged ≥18 years with a postoperative diagnosis of UC...
April 25, 2018: Inflammatory Bowel Diseases
https://www.readbyqxmd.com/read/29688472/management-of-pouchitis-and-other-common-complications-of-the-pouch
#14
Robin L Dalal, Bo Shen, David A Schwartz
Restorative proctocolectomy with ileal pouch-anal anastomosis (IPAA) has become the preferred surgical treatment for refractory or complicated ulcerative colitis (UC) and familial adenomatous polyposis (FAP). Pouchitis is the most common complication of this procedure and can occur in about 50% of patients. Treatment of pouchitis depends on the phenotype of disease. Pouchitis can be classified as acute, chronic/refractory, or secondary pouchitis, which includes pouchitis occurring due to Crohn's disease (CD)...
April 23, 2018: Inflammatory Bowel Diseases
https://www.readbyqxmd.com/read/29668894/endoscopic-treatment-of-ileal-pouch-sinus
#15
Nan Lan, Bo Shen
Background and aims: Pouch sinus is a serious complication in patients undergoing ileal pouch-anal anastomosis. The aim of this study was to verify the efficacy and safety of endoscopic needle knife sinusotomy (NKSi) in the management of pouch sinus. Methods: All consecutive patients with a pouch sinus treated with NKSi from 2008 to 2016 were identified. The primary outcomes were complete healing of the sinus and pouch survival. Results: A total of 109 patients were included...
June 8, 2018: Inflammatory Bowel Diseases
https://www.readbyqxmd.com/read/29660321/reliability-among-central-readers-in-the-evaluation-of-endoscopic-disease-activity-in-pouchitis
#16
Mark A Samaan, Bo Shen, Mahmoud H Mosli, Guangyong Zou, William J Sandborn, Lisa M Shackelton, Sigrid Nelson, Larry Stitt, Stuart Bloom, Darrell S Pardi, Paolo Gionchetti, James Lindsay, Simon Travis, Ailsa Hart, Mark S Silverberg, Brian G Feagan, Geert R D'Haens, Vipul Jairath
BACKGROUND & AIMS: Pouchitis is a common adverse event after proctocolectomy with ileal pouch anal anastomosis for ulcerative colitis. Evaluation of pouchitis disease activity and response to treatment requires use of validated indices. We assessed the reliability of items evaluating endoscopic pouchitis disease activity. METHODS: Twelve panelists used a modified RAND appropriateness methodology to rate the appropriateness of items evaluating endoscopic pouchitis disease activity derived from a systematic review, and also identified additional potential endoscopic items based on expert opinion...
April 13, 2018: Gastrointestinal Endoscopy
https://www.readbyqxmd.com/read/29650924/-endoscopy-assisted-partial-duodenal-resection-for-duodenal-adenoma-in-a-patient-with-familial-adenomatous-polyposis
#17
Tomoaki Hirashima, Shinobu Ohnuma, Hideaki Karasawa, Kazuhiro Watanabe, Hirofumi Imoto, Takeshi Aoki, Katsuyoshi Kudoh, Naoki Tanaka, Munenori Nagao, Hiroaki Musha, Fuyuhiko Motoi, Takashi Kamei, Takeshi Naitoh, Michiaki Unno
We here report a case of endoscopy-assisted partial duodenal resection for duodenal adenoma in a patient with familial adenomatous polyposis(FAP). A male underwent total proctocolectomy with ileal pouch anal anastomosis in 1997. Since 2004, duodenal adenomas occurred and the atypical grade of adenoma was gradually aggravated. Therefore, he underwent endoscopy-assisted partial duodenal resection in 2013. The pathological finding of the specimen showed well-differentiated tubular adenocarcinoma(pM, ly0, v0). No recurrence has been observed at 4 years after the operation...
March 2018: Gan to Kagaku Ryoho. Cancer & Chemotherapy
https://www.readbyqxmd.com/read/29627174/short-term-outcomes-in-children-undergoing-restorative-proctocolectomy-with-ileal-pouch-anal-anastomosis
#18
Katerina Dukleska, Loren Berman, Allison A Aka, Charles D Vinocur, Erin A Teeple
INTRODUCTION: Patients with familial adenomatous polyposis (FAP) and ulcerative colitis (UC) commonly undergo restorative proctocolectomy with ileal-pouch anal anastomosis (RP-IPAA). We sought to describe patient characteristics and postoperative outcomes in this patient population. METHODS: Using the National Surgical Quality Improvement Program-Pediatric Participant Use Files from 2012 to 2015, children who were 6-18years old who underwent RP-IPAA for FAP or UC were identified...
March 7, 2018: Journal of Pediatric Surgery
https://www.readbyqxmd.com/read/29617820/fecal-incontinence-in-inflammatory-bowel-disease-a-systematic-review-and-meta-analysis
#19
Phillip Gu, M Ellen Kuenzig, Gilaad G Kaplan, Mark Pimentel, Ali Rezaie
Background: Understanding of the prevalence, pathophysiology, and management of fecal incontinence (FI) in inflammatory bowel disease (IBD) patients without an ileal pouch anal anastomosis (IPAA) is suboptimal. We conducted a systematic review and meta-analysis on the prevalence, pathophysiology, and management of primary FI in IBD patients without IPAA. Methods: We searched MEDLINE, EMBASE, and Cochrane Database of Systematic Reviews (1966 through March 2017) for studies on the prevalence, physiology, or management of FI in IBD patients without IPAA...
May 18, 2018: Inflammatory Bowel Diseases
https://www.readbyqxmd.com/read/29564356/chinese-research-into-severe-ulcerative-colitis-has-increased-in-quantity-and-complexity
#20
Cheng-Xin Luo, Zhong-Hui Wen, Yu Zhen, Zhu-Jun Wang, Jing-Xi Mu, Min Zhu, Qin Ouyang, Hu Zhang
AIM: To investigate the current state of research output from Chinese studies into severe ulcerative colitis (SUC) using a bibliometric analysis of publications. METHODS: The contents of the Chinese periodical databases WANFANG, VIP, and China National Knowledge Infrastructure were searched for all papers regarding UC or SUC published in last the 15 years (from 2001 to 2015). The number of publications in each year was recorded to assess the temporal trends of research output...
March 16, 2018: World Journal of Clinical Cases
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