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https://www.readbyqxmd.com/read/29759435/temporal-trends-in-and-factors-associated-with-use-of-single-versus-dual-coil-implantable-cardioverter-defibrillator-leads-data-from-the-ncdr-icd-registry
#1
Sean D Pokorney, Craig S Parzynski, James P Daubert, Donald D Hegland, Paul D Varosy, Jeptha P Curtis, Sana M Al-Khatib
OBJECTIVES: This analysis evaluated temporal trends and factors associated with the use of dual-coil implantable cardioverter-defibrillator (ICD) leads. BACKGROUND: Data suggest that dual-coil ICD leads are not associated with lower mortality and can be more difficult to extract than single-coil leads. METHODS: A total of 435,772 patients at 1,690 hospitals underwent ICD lead insertion in the National Cardiovascular Data Registry's ICD Registry between April 2010 and December 2015...
June 2017: JACC. Clinical Electrophysiology
https://www.readbyqxmd.com/read/29755626/the-impact-of-admission-serum-creatinine-on-major-adverse-clinical-events-in-st-segment-elevation-myocardial-infarction-patients-undergoing-primary-percutaneous-coronary-intervention
#2
Poornima Vinod, Taylor Kann, Shyam Polaconda, Alibel Bello, Mohamed Khayata, Fernando Munoz, Vinod Krishnappa, Rupesh Raina
Background: Impaired renal function has been shown in previous studies to be an independent predictor of cardiovascular adverse events amongst patients admitted for percutaneous coronary intervention (PCI) following ST-segment elevation myocardial infarction (STEMI). This study investigates the impact of admission serum creatinine (SCr) on major cardiovascular outcomes among STEMI patients undergoing PCI. Methods: A retrospective study of patients admitted for PCI following STEMI was conducted using the National Cardiovascular Database Action Registry (NCDR) at Cleveland Clinic Akron General (CCAG) Hospital...
April 2018: Cardiology Research
https://www.readbyqxmd.com/read/29724164/signs-symptoms-and-treatment-patterns-across-serial-ambulatory-cardiology-visits-in-patients-with-heart-failure-insights-from-the-ncdr-pinnacle%C3%A2-registry
#3
Larry A Allen, Fengming Tang, Philip Jones, Tracie Breeding, Angelo Ponirakis, Stuart J Turner
BACKGROUND: Due to a relative lack of outpatient heart failure (HF) clinical registries, we aimed to describe symptoms, signs, and medication treatment among ambulatory patients with heart failure (HF) over time. METHODS: Using health records from 234 PINNACLE (Practice Innovation and Clinical Excellence) U.S. cardiology practices (2008-2014), serial visits for patients with HF were characterized. Symptoms, signs, and HF medications (angiotensin-converting enzyme inhibitors [ACEI], angiotensin receptor blockers [ARB], beta blockers [BB], and diuretics) were compared between visits...
May 3, 2018: BMC Cardiovascular Disorders
https://www.readbyqxmd.com/read/29603575/time-trends-in-service-provision-and-survival-outcomes-for-renal-cancer-patients-treated-by-nephrectomy-in-england-2000-2010
#4
Ray C J Hsu, Matthew Barclay, Molly A Loughran, Georgios Lyratzopoulos, Vincent J Gnanapragasam, James N Armitage
OBJECTIVE: To describe the temporal trends in nephrectomy practice and outcomes for English renal cell carcinoma (RCC) patients. PATIENTS & METHODS: Adult RCC nephrectomy patients treated between 2000 and 2010 were identified in the National Cancer Data Repository (NCDR) and Hospital Episode Statistics (HES) and followed up for death through 2015 (n=30,763). We estimated the annual frequency for each nephrectomy type, the hospital and surgeon numbers and their case volumes...
March 30, 2018: BJU International
https://www.readbyqxmd.com/read/29480207/age-at-death-and-causes-of-death-in-patients-with-huntington-disease-in-norway-in-1986-2015
#5
Olga Karin Solberg, Petra Filkuková, Jan C Frich, Kristin J Billaud Feragen
BACKGROUND: The literature offers discrepant findings regarding age at death in individuals with Huntington disease (HD). OBJECTIVE: To study the age at death and causes of death in males and females with a diagnosis of HD in Norway. METHODS: Registry study of deaths in 1986-2015 using data from two national registries: the Norwegian Cause of Death Registry (NCDR) and the registry of the Centre for Rare Disorders (CRD), Oslo University Hospital...
2018: Journal of Huntington's Disease
https://www.readbyqxmd.com/read/29359497/adoption-of-the-transradial-approach-for-percutaneous-coronary-intervention-and-rates-of-vascular-complications-following-transfemoral-procedures-insights-from-ncdr
#6
Marwan Badri, Timothy Shapiro, Yongfei Wang, Karl E Minges, Jeptha P Curtis, William A Gray
OBJECTIVES: This study was designed to examine the association between adopting the transradial approach for percutaneous coronary intervention (PCI) and rates of vascular complications following transfemoral PCI. BACKGROUND: Recent studies raised concerns that operators adopting the transradial approach may lose their transfemoral access skills and experience increased rates of vascular complications. METHODS: Retrospective analysis of data from the NCDR CathPCI Registry to examine the rates of vascular complications among physicians who were femoral operators (>90% of cases) in 2010-2011 and later adopted the transradial approach to PCI among low-, intermediate-, or high-level adopters (≤33%, 34-66%, and >66%, respectively) in 2014-2015...
January 23, 2018: Catheterization and Cardiovascular Interventions
https://www.readbyqxmd.com/read/29224646/association-of-insurance-type-with-receipt-of-oral-anticoagulation-in-insured-patients-with-atrial-fibrillation-a-report-from-the-american-college-of-cardiology-ncdr-pinnacle-registry
#7
MULTICENTER STUDY
Celina M Yong, Yuyin Liu, Patricia Apruzzese, Gheorghe Doros, Christopher P Cannon, Thomas M Maddox, Anil Gehi, Jonathan C Hsu, Steven A Lubitz, Salim Virani, Mintu P Turakhia
BACKGROUND: It is poorly understood whether insurance type may be a major contributor to the underuse of oral anticoagulation (OAC) among patients with atrial fibrillation (AF), particularly for novel oral anticoagulants (NOACs). METHODS: We performed a retrospective cohort registry study of patients with insurance, AF, CHA2 DS2 -VASc ≥2, and at least one outpatient encounter recorded in the ACC NCDR's PINNACLE Registry between January 1, 2011 and December 31, 2014...
January 2018: American Heart Journal
https://www.readbyqxmd.com/read/29211243/evidence-of-hidden-leprosy-in-a-supposedly-low-endemic-area-of-brazil
#8
Fred Bernardes, Natália Aparecida de Paula, Marcel Nani Leite, Thania Loyola Cordeiro Abi-Rached, Sebastian Vernal, Moises Batista da Silva, Josafá Gonçalves Barreto, John Stewart Spencer, Marco Andrey Cipriani Frade
OBJECTIVES: Show that hidden endemic leprosy exists in a municipality of inner São Paulo state (Brazil) with active surveillance actions based on clinical and immunological evaluations. METHODS: The study sample was composed by people randomly selected by a dermatologist during medical care in the public emergency department and by active surveillance carried out during two days at a mobile clinic. All subjects received a dermato-neurological examination and blood sampling to determine anti-PGL-I antibody titers by enzyme-linked immunosorbent assay (ELISA)...
December 2017: Memórias do Instituto Oswaldo Cruz
https://www.readbyqxmd.com/read/29179731/can-routine-data-be-used-to-support-cancer-clinical-trials-a-historical-baseline-on-which-to-build-retrospective-linkage-of-data-from-the-tact-cruk-01-001-breast-cancer-trial-and-the-national-cancer-data-repository
#9
Lucy Suzanne Kilburn, Maria Aresu, Jane Banerji, Peter Barrett-Lee, Paul Ellis, Judith Margaret Bliss
BACKGROUND: Randomised clinical trials (RCTs) are the gold standard for evaluating new cancer treatments. They are, however, expensive to conduct, particularly where long-term follow-up of participants is required. Tracking participants via routine datasets could provide a cost-effective alternative for ascertaining follow-up information required to evaluate disease outcomes. This project explores the potential for routine data to inform cancer trials, using, the historical National Cancer Data Repository (NCDR) for English NHS sites and, for validation, mature data available from the TACT trial...
November 23, 2017: Trials
https://www.readbyqxmd.com/read/29105329/if-you-prick-us-do-we-not-bleed
#10
EDITORIAL
Ameera Ahmed, Timothy D Henry
Women have higher post PCI bleeding complications which in turn contributes to higher post PCI mortality. Bivalirudin decreases bleeding events in both men and women when compared to use of both heparin and GPI but bleeding avoidance strategies such as radial artery access or avoiding GPI may modify that benefit. The NCDR bleeding risk score incorporates gender and is predictive of both bleeding complications and mortality. The ideal strategy to reduce bleeding will depend on the specific patient, local practice patterns, and ideally cost effectiveness...
November 1, 2017: Catheterization and Cardiovascular Interventions
https://www.readbyqxmd.com/read/29102582/variation-in-the-adoption-of-transradial-access-for-st-segment-elevation-myocardial-infarction-insights-from-the-ncdr-cathpci-registry
#11
Javier A Valle, Lisa A Kaltenbach, Steven M Bradley, Robert W Yeh, Sunil V Rao, Hitinder S Gurm, Ehrin J Armstrong, John C Messenger, Stephen W Waldo
OBJECTIVES: The study sought to define patient, operator, and institutional factors associated with transradial access (TRA) in ST-segment elevation myocardial infarction (STEMI) percutaneous coronary intervention (PCI), the variation in use across operators and institutions, and the relationship with mortality and bleeding. BACKGROUND: TRA for PCI in STEMI is underutilized. Factors associated with TRA are not well described, nor is there variation across operators and institutions or their relationship with outcomes...
November 27, 2017: JACC. Cardiovascular Interventions
https://www.readbyqxmd.com/read/29102348/coronary-venous-dissection-from-left-ventricular-lead-placement-during-cardiac-resynchronization-therapy-with-defibrillator-implantation-and-associated-in-hospital-adverse-events-from-the-ncdr-icd-registry
#12
Jonathan C Hsu, Paul D Varosy, Haikun Bao, Thomas A Dewland, Jeptha P Curtis, Gregory M Marcus
Coronary venous dissection is a known complication of left ventricular lead placement during implantation of a cardiac resynchronization with defibrillator (CRT-D) system. A large-scale evaluation of the prevalence of coronary venous dissection and associated in-hospital clinical outcomes has not been performed. We sought to identify predictors of coronary venous dissection and evaluate subsequent in-hospital adverse events in those with the complication. We studied 140,991 first-time CRT-D recipients in the implantable cardioverter-defibrillator (ICD) Registry implanted between 2006 and 2011...
January 1, 2018: American Journal of Cardiology
https://www.readbyqxmd.com/read/29070501/centers-for-medicare-and-medicaid-services-decision-to-reconsider-coverage-indications-for-icds-where-to-now
#13
Sana M Al-Khatib, Anne M Gillis, Anne B Curtis
No abstract text is available yet for this article.
January 23, 2018: Circulation
https://www.readbyqxmd.com/read/28987459/long-term-morbidity-and-mortality-after-implantable-cardioverter-defibrillator-implantation-with-procedural-complication-a-report-from-the-national-cardiovascular-data-registry
#14
Ryan Kipp, Jonathan C Hsu, James Freeman, Jeptha Curtis, Haikun Bao, Kurt S Hoffmayer
BACKGROUND: Long-term outcomes and predictors of mortality after implantable cardioverter-defibrillator (ICD) implantation related complication are unclear. OBJECTIVE: The purpose of this study was to determine the risk of mortality and hospitalization after complication during ICD implantation and identify predictors of adverse outcomes. METHODS: We performed a retrospective registry study of Medicare beneficiaries who were first-time ICD recipients enrolled in the National Cardiovascular Data Registry ICD Registry between January 2006 and March 2010...
October 5, 2017: Heart Rhythm: the Official Journal of the Heart Rhythm Society
https://www.readbyqxmd.com/read/28961690/ncdr-a-comprehensive-resource-of-non-coding-rnas-involved-in-drug-resistance
#15
Enyu Dai, Feng Yang, Jing Wang, Xu Zhou, Qian Song, Weiwei An, Lihong Wang, Wei Jiang
Summary: As a promising field of individualized therapy, non-coding RNA pharmacogenomics promotes the understanding of different individual responses to certain drugs and acts as a reasonable reference for clinical treatment. However, relevant information is scattered across the published literature, which is inconvenient for researchers to explore non-coding RNAs that are involved in drug resistance. To address this, we systemically identified validated and predicted drug resistance-associated microRNAs and long non-coding RNAs through manual curation and computational analysis...
August 17, 2017: Bioinformatics
https://www.readbyqxmd.com/read/28917495/complications-associated-with-implantable-cardioverter-defibrillators-in-adults-with-congenital-heart-disease-or-left-ventricular-noncompaction-cardiomyopathy-from-the-ncdr-%C3%A2-implantable-cardioverter-defibrillator-registry
#16
MULTICENTER STUDY
Marye J Gleva, Yongfei Wang, Jeptha P Curtis, Charles I Berul, Charles B Huddleston, Jeanne E Poole
Patients with childhood heart disease are living longer and entering adulthood, and may undergo implantable cardioverter-defibrillator (ICD) implantation to reduce the risk of sudden death. We evaluated the characteristics of adult patients with congenital heart disease or left ventricular noncompaction cardiomyopathy (LVNC) in the National Cardiovascular Disease Registry ICD Registry and determined ICD-related in-hospital complications. Patients with LVNC or transposition of the great arteries, tetralogy of Fallot, Ebstein's anomaly, atrial septal defect, ventricular septal defect, or common ventricle were identified in the registry...
November 15, 2017: American Journal of Cardiology
https://www.readbyqxmd.com/read/28886925/the-ncdr-icd%C3%A2-registry-a-foundation-for-quality%C3%A2-improvement
#17
EDITORIAL
Frederick M Masoudi, William J Oetgen
No abstract text is available yet for this article.
August 31, 2017: Journal of the American College of Cardiology
https://www.readbyqxmd.com/read/28882885/modeling-major-adverse-outcomes-of-pediatric-and-adult-patients-with-congenital-heart-disease-undergoing-cardiac-catheterization-observations-from-the-ncdr-impact-registry-national-cardiovascular-data-registry-improving-pediatric-and-adult-congenital-treatment
#18
MULTICENTER STUDY
Natalie Jayaram, John A Spertus, Kevin F Kennedy, Robert Vincent, Gerard R Martin, Jeptha P Curtis, David Nykanen, Phillip M Moore, Lisa Bergersen
BACKGROUND: Risk standardization for adverse events after congenital cardiac catheterization is needed to equitably compare patient outcomes among different hospitals as a foundation for quality improvement. The goal of this project was to develop a risk-standardization methodology to adjust for patient characteristics when comparing major adverse outcomes in the NCDR's (National Cardiovascular Data Registry) IMPACT Registry (Improving Pediatric and Adult Congenital Treatment). METHODS: Between January 2011 and March 2014, 39 725 consecutive patients within IMPACT undergoing cardiac catheterization were identified...
November 21, 2017: Circulation
https://www.readbyqxmd.com/read/28870145/real-world-use-and-modeled-impact-of-glucose-lowering-therapies-evaluated-in-recent-cardiovascular-outcomes-trials-an-ncdr%C3%A2-research-to-practice-project
#19
Suzanne V Arnold, Silvio E Inzucchi, Fengming Tang, Darren K McGuire, Sanjeev N Mehta, Thomas M Maddox, Abhinav Goyal, Laurence S Sperling, Daniel Einhorn, Nathan D Wong, Kamlesh Khunti, Carolyn Sp Lam, Mikhail Kosiborod
Aims Recent trials (EMPA-REG OUTCOME and Liraglutide Effect and Action in Diabetes: Evaluation of Cardiovascular Outcome Results [LEADER]) have shown improved cardiovascular (CV) mortality with specific currently available glucose-lowering medications (empagliflozin and liraglutide, respectively), but were limited to selected patient populations. We sought to evaluate the current use and potential real-world impact of empagliflozin (and other sodium-glucose co-transporter 2 inhibitors [SGLT2is]) and liraglutide (and other glucagonlike peptide-1 receptor agonist [GLP-1 RAs]) among patients in the Diabetes Collaborative Registry (DCR)...
October 2017: European Journal of Preventive Cardiology
https://www.readbyqxmd.com/read/28864443/conscious-sedation-versus-general-anesthesia-for-transcatheter-aortic-valve-replacement-insights-from-the-national-cardiovascular-data-registry-society-of-thoracic-surgeons-american-college-of-cardiology-transcatheter-valve-therapy-registry
#20
COMPARATIVE STUDY
Matthew C Hyman, Sreekanth Vemulapalli, Wilson Y Szeto, Amanda Stebbins, Prakash A Patel, Roland A Matsouaka, Howard C Herrmann, Saif Anwaruddin, Taisei Kobayashi, Nimesh D Desai, Prashanth Vallabhajosyula, Fenton H McCarthy, Robert Li, Joseph E Bavaria, Jay Giri
BACKGROUND: Conscious sedation is used during transcatheter aortic valve replacement (TAVR) with limited evidence as to the safety and efficacy of this practice. METHODS: The National Cardiovascular Data Registry Society of Thoracic Surgeons/American College of Cardiology Transcatheter Valve Therapy Registry was used to characterize the anesthesia choice and clinical outcomes of all US patients undergoing elective percutaneous transfemoral TAVR between April 1, 2014, and June 30, 2015...
November 28, 2017: Circulation
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