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vitamin c serum

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https://www.readbyqxmd.com/read/29143130/two-threshold-levels-of-vitamin-d-and-the-prevalence-of-comorbidities-in-outpatients-of-a-tertiary-hospital
#1
I N Furuie, M J J Mauro, S Petruzziello, S C Riechi, R R Petterle, C L Boguszewski, V Z C Borba
This study evaluated the number of comorbidities between two normal values of 25OHD in outpatients during 1 year of 25OHD measurements. Five hundred twenty-nine outpatients were included, patients with 25OHD ≥ 20 and < 30 ng/mL had the higher number of comorbidities, suggesting that for this specific population, 25OHD ≥ 30 ng/mL would be more appropriate. INTRODUCTION : This study evaluated the comorbidities between two values of 25OHD in outpatients of a tertiary hospital. METHODS: This is a cross-sectional study with measures of 25OHD in 1-year period, excluding 25OHD < 20 and > 50 ng/mL, clinical research participants, and liver disease and chronic renal failure patients...
November 15, 2017: Osteoporosis International
https://www.readbyqxmd.com/read/29137635/the-association-between-serum-25-hydroxyvitamin-d3-concentration-and-serum-lipids-in-the-rural-population-of-china
#2
Huina Ge, Hualei Sun, Teng Wang, Xinxin Liu, Xing Li, Fei Yu, Han Han, Jun Wang, Wenjie Li
BACKGROUND: Vitamin D deficiency is implicated in some diseases, including cardiovascular. Few studies have assessed the correlation between 25-hydroxyvitamin D3 [25(OH) D3] and serum lipids. In this study, we explored the correlation between serum 25(OH) D3 concentrations and serum lipids with a typical sample of the rural population in China. METHODS: Face-to-face research was used to gather some basic information. Fasting serum concentrations of 25-(OH) D3, total cholesterol (TC), triglyceride (TG), HDL cholesterol (HDL-C) and, LDL cholesterol (LDL-C) tested in the laboratory...
November 14, 2017: Lipids in Health and Disease
https://www.readbyqxmd.com/read/29136033/sun-exposure-in-pigs-increases-the-vitamin-d-nutritional-quality-of-pork
#3
D Enette Larson-Meyer, Bennett C Ingold, Samanta R Fensterseifer, Kathleen J Austin, Perry J Wechsler, Bruce W Hollis, Andrew J Makowski, Brenda M Alexander
There is a high prevalence of vitamin D insufficiency and deficiency worldwide likely because of both limited sun-exposure and inadequate dietary intake. Meat, including pork, is not typically considered a dietary source of vitamin D, possibly because of management practices that raise pigs in confinement. This experiment determined the vitamin D content of loin and subcutaneous adipose tissue in sun-exposed finisher pigs. Two separate groups of pigs were used. The first group (28 white Landrace-Duroc) was assigned at random to either sunlight exposure (SUN) in spring and summer or confinement per standard practice (Control)...
2017: PloS One
https://www.readbyqxmd.com/read/29134617/vascular-calcification-is-not-related-to-serum-fetuin-a-and-osteopontin-levels-in-hemodialysis-patients
#4
O Ulutas, M C Taskapan, A Dogan, T Baysal, H Taskapan
INTRODUCTION: Vascular calcification (VC) in hemodialysis (HD) patients is a sign of severe cardiovascular disease and can predict cardiovascular outcomes. Fetuin-A and osteopontin (OPN) inhibit VC. Serum fetuin-A levels are lower in patients with end-stage kidney disease (ESKD) and in those who are on chronic HD therapy. However, there are limited data concerning OPN in patients who are on dialysis. The aim of our study was to determine VC in HD patients, the relationship between VC and 25-OH-vitamin D, fetuin-A, and OPN levels, and independent predictors of VC...
November 13, 2017: International Urology and Nephrology
https://www.readbyqxmd.com/read/29134242/serum-parathyroid-hormone-is-associated-with-increased-cortical-porosity-of-the-inner-transitional-zone-at-the-proximal-femur-in-postmenopausal-women-the-troms%C3%A3-study
#5
M Osima, T T Borgen, M Lukic, G Grimnes, R M Joakimsen, E F Eriksen, Å Bjørnerem
Serum parathyroid hormone (PTH) was associated with increased bone turnover markers and cortical porosity of the inner transitional zone at the proximal femur. These results suggest that PTH through increased intracortical bone turnover leads to trabecularisation of inner cortical bone in postmenopausal women. INTRODUCTION: Vitamin D deficiency leads to secondary hyperparathyroidism and increased risk for fractures, whereas its association with cortical porosity is less clear. We tested (i) whether serum 25-hydroxyvitamin D (25(OH)D) and PTH were associated with cortical porosity and (ii) whether the associations of 25(OH)D) and PTH with fracture risk are dependent on cortical porosity...
November 14, 2017: Osteoporosis International
https://www.readbyqxmd.com/read/29128341/vitamin-d-and-health-care-costs-results-from-two-independent-population-based-cohort-studies
#6
A Hannemann, H Wallaschofski, M Nauck, P Marschall, S Flessa, H J Grabe, C O Schmidt, S E Baumeister
BACKGROUND & AIMS: Vitamin D deficiency is associated with higher morbidity. However, there is few data regarding the effect of vitamin D deficiency on health care costs. This study examined the cross-sectional and longitudinal associations between the serum 25-hydroxy vitamin D concentration (25OHD) and direct health care costs and hospitalization in two independent samples of the general population in North-Eastern Germany. METHODS: We studied 7217 healthy individuals from the 'Study of Health in Pomerania' (SHIP n = 3203) and the 'Study of Health in Pomerania-Trend' (SHIP-Trend n = 4014) who had valid 25OHD measurements and provided data on annual total costs, outpatient costs, hospital stays, and inpatient costs...
October 31, 2017: Clinical Nutrition: Official Journal of the European Society of Parenteral and Enteral Nutrition
https://www.readbyqxmd.com/read/29126718/vitamin-d-and-antiphospholipid-syndrome-a-retrospective-cohort-study-and-meta-analysis
#7
REVIEW
Leyre Riancho-Zarrabeitia, Maite Cubería, Pedro Muñoz, Marcos López-Hoyos, Silvia García-Canale, Mayte García-Unzueta, José L Hernández, Víctor M Martínez-Taboada
OBJECTIVES: (a) To determine serum 25-OH vitamin D (vitD) levels in primary antiphospholipid syndrome (APS) and to compare them with patients with positive antiphospholipid serology who do not meet clinical criteria for APS, and with healthy controls. (b) To analyze the association of vitD levels with both the clinical manifestations and the immunological profile of patients with primary APS. (c) To perform a meta-analysis evaluating potential differences in serum vitD levels between APS and controls as well as the frequency of vitD deficiency in APS patients...
October 12, 2017: Seminars in Arthritis and Rheumatism
https://www.readbyqxmd.com/read/29123173/effect-of-vitamin-d-supplementation-on-inflammation-and-nuclear-factor-kappa-b-activity-in-overweight-obese-adults-a-randomized-placebo-controlled-trial
#8
Aya Mousa, Negar Naderpoor, Josphin Johnson, Karly Sourris, Maximilian P J de Courten, Kirsty Wilson, Robert Scragg, Magdalena Plebanski, Barbora de Courten
In-vitro studies suggest that vitamin D reduces inflammation by inhibiting nuclear factor kappa-B (NFκB) activity. Yet, no trials have examined the effects of vitamin D supplementation on NFκB activity in-vivo in humans. We conducted a double-blind randomized trial (RCT) examining effects of vitamin D supplementation on inflammatory markers and NFκB activity in peripheral blood mononuclear cells (PBMCs). Sixty-five overweight/obese, vitamin D-deficient (25-hydroxyvitamin D [25(OH)D] ≤ 50 nmol/L) adults were randomized to a single 100,000 IU bolus followed by 4,000 IU daily cholecalciferol or matching placebo for 16 weeks...
November 9, 2017: Scientific Reports
https://www.readbyqxmd.com/read/29118583/the-association-of-serum-vitamin-d-concentration-and-ventricular-dysfunction-among-patients-with-acute-coronary-syndrome
#9
Kamal Khademvatani, Mirhosein Seyed Mohammadzad, Zahra Yekta, Omid Hadizadeh
Objective: To determine if vitamin D deficiency was associated with higher odds of left ventricular dysfunction among patients with acute coronary syndrome (ACS) and, if so, to determine whether this association was mediated by increased inflammation as measured by C-reactive protein (CRP) and white blood cell count (WBC). Methods: This was a cross-sectional study of 170 participants with ACS. Multiple logistic regression was used to examine the association between the outcome of ventricular performance and serum vitamin D concentrations...
2017: Therapeutics and Clinical Risk Management
https://www.readbyqxmd.com/read/29116467/vitamin-d-supplementation-decreases-serum-27-hydroxycholesterol-in-a-pilot-breast-cancer-trial
#10
Catherine C Going, Ludmila Alexandrova, Kenneth Lau, Christine Y Yeh, David Feldman, Sharon J Pitteri
PURPOSE: 27-hydroxycholesterol (27HC), an endogenous selective estrogen receptor modulator (SERM), drives the growth of estrogen receptor-positive (ER+) breast cancer. 1,25-dihydroxyvitamin D (1,25(OH)2D), the active metabolite of vitamin D, is known to inhibit expression of CYP27B1, which is very similar in structure and function to CYP27A1, the synthesizing enzyme of 27HC. Therefore, we hypothesized that 1,25(OH)2D may also inhibit expression of CYP27A1, thereby reducing 27HC concentrations in the blood and tissues that express CYP27A1, including breast cancer tissue...
November 7, 2017: Breast Cancer Research and Treatment
https://www.readbyqxmd.com/read/29110607/serum-carotenoids-and-risks-of-diabetes-and-diabetic-retinopathy-in-a-chinese-population-sample
#11
C She, F Shang, K Zhou, N Liu
OBJECTIVE: Diabetes mellitus (DM) and diabetic retinopathy (DR) are associated with oxidative stress and carotenoids have antioxidant properties. This study aimed to test the relationship between serum carotenoid concentrations and the risk for DM and DR. METHODS: This is a cross-sectional study of the Chinese urban population. A total of 747 subjects, consisting of 272 DR patients, 190 diabetic patients without retinopathy, and 285 non-diabetes mellitus healthy controls, were recruited to this study...
November 5, 2017: Current Molecular Medicine
https://www.readbyqxmd.com/read/29108191/-an-interpretation-of-the-aasld-practice-guideline-on-the-diagnosis-and-management-of-nonalcoholic-fatty-liver-disease-in-2017
#12
Y M Nan, N Fu, W C Li, L L Kong, X W Yuan, S Y Zhang, L D Liu, Y Lu, L Y Cui
The American Association for the Study of Liver Diseases (AASLD) updated and published the Practice Guidance for the Diagnosis and Management of Nonalcoholic Fatty Liver Disease (NAFLD) in July 2017, which provides recommendations for the accurate diagnosis, treatment, and effective prevention of NAFLD. Related metabolic diseases should be considered during the initial evaluation of patients suspected of NAFLD. Noninvasive diagnostic techniques including transient elastography, magnetic resonance elastography, and serum biochemical models should be used to evaluate the development and progression of liver fibrosis in patients with NAFLD...
September 20, 2017: Zhonghua Gan Zang Bing za Zhi, Zhonghua Ganzangbing Zazhi, Chinese Journal of Hepatology
https://www.readbyqxmd.com/read/29106966/single-step-preparation-of-selected-biological-fluids-for-the-high-performance-liquid-chromatographic-analysis-of-fat-soluble-vitamins-and-antioxidants
#13
Giacomo Lazzarino, Salvatore Longo, Angela Maria Amorini, Valentina Di Pietro, Serafina D'Urso, Giuseppe Lazzarino, Antonio Belli, Barbara Tavazzi
Fat-soluble vitamins and antioxidants are of relevance in health and disease. Current methods to extract these compounds from biological fluids mainly need use of multi-steps and multi organic solvents. They are time-consuming and difficult to apply to treat simultaneously large sample number. We here describe a single-step, one solvent extraction of fat-soluble vitamins and antioxidants from biological fluids, and the chromatographic separation of all-trans-retinoic acid, 25-hydroxycholecalciferol, all-trans-retinol, astaxanthin, lutein, zeaxanthin, trans-β-apo-8'-carotenal, γ-tocopherol, β-cryptoxanthin, α-tocopherol, phylloquinone, lycopene, α-carotene, β-carotene and coenzyme Q10...
December 8, 2017: Journal of Chromatography. A
https://www.readbyqxmd.com/read/29105489/effect-of-different-periods-of-chronic-heat-stress-with-or-without-vitamin-c-supplementation-on-bone-and-selected-serum-parameters-of-broilers
#14
Najmeh Mosleh, Tahoora Shomali, Fahimeh Nematollahi, Zahra Ghahramani, Mohammad Saeid Ahrari Khafi, Fatemeh Namazi
This study evaluates the effect of different periods of chronic heat stress (CHS) on selected bone and serum parameters of broilers with or without vitamin C administration. Ninety 23 day old-chickens were randomly allocated into 7 groups: 1. control, 2. short term CHS (5 days), 3. short term CHS + vitamin C (12 g/100L drinking water of a 50% product) 4. medium term CHS (10 days), 5. medium term CHS + vitamin C, 6. long term CHS (20 days) and 7. long term CHS + vitamin C. In heat stressed groups the temperature was increased to 39±1°C for 8h/day...
November 6, 2017: Avian Pathology: Journal of the W.V.P.A
https://www.readbyqxmd.com/read/29104377/seasonal-variation-in-vitamin-d-in-association-with-age-inflammatory-cytokines-anthropometric-parameters-and-lifestyle-factors-in-older-adults
#15
Leticia Elizondo-Montemayor, Elena C Castillo, Carlos Rodríguez-López, José R Villarreal-Calderón, Merit Gómez-Carmona, Sofia Tenorio-Martínez, Bianca Nieblas, Gerardo García-Rivas
Vitamin D deficiency is present even in sunny regions. Ageing decreases pre-vitamin D production in the skin and is associated with altered cytokine profile. We performed a multivariate analysis considering lifestyle factors, anthropometric, and inflammatory markers according to seasonal variation in Mexican healthy older adults. The same cohort was followed during 12 months. Vitamin D deficiency/insufficiency was found in 91.3% of the subjects despite living in appropriate latitude (25°40'0″N). 25(OH)D levels remained below <30 ng/mL through all seasons...
2017: Mediators of Inflammation
https://www.readbyqxmd.com/read/29099117/deficiencia-de-vitamina-d-en-madres-y-neonatos-mexicanos
#16
E C Ochoa-Correa, P A García-Hernández, J Z Villarreal-Pérez, C Treviño-Garza, I Rodríguez-Balderrama, L E Martínez-de Villarreal, C A Zapata-Castilleja, M E De la O-Cavazos
Objective: The purpose of this study is to establish the prevalence of vitamin D deficiency and their newborns and analyze the risk factors related to this deficiency. Methods: This is an observational, transversal, and prospective study. It included 191 puerperal women and their full-term newborns. Serum 25 hydroxyvitamin D values were analyzes by enzyme immunoassay. Results: 61% of the puerperal presented deficiency and 26% insufficiency of vitamin D...
2017: Gaceta Médica de México
https://www.readbyqxmd.com/read/29095011/consumption-of-nutrients-with-antioxidant-action-and-its-relationship-with-lipid-profile-and-oxidative-stress-in-student-users-of-a-university-restaurant
#17
Sueli Maria Teixeira Lima, Kaluce Gonçalves De Sousa Almondes, Kyria Jayanne Clímaco Cruz, Heila Dias de Sousa Pinho Aguiar, Camila Maria Simplício Revoredo, Betzabeth Slater, Jennifer Beatriz Silva Morais, Dilina Do Nascimento Marreiro, Nadir Do Nascimento Nogueira
INTRODUCTION: The relationship between diet and health has aroused scientific interest, especially the consumption of antioxidant nutrients naturally present in foods, because of its action against the deleterious effects of free radicals in the body. OBJECTIVE: This study aimed to estimate the intake of antioxidant nutrients and its relationship with lipid profile and oxidative stress in student users of a university restaurant in comparison with non-users. METHODS: This cross-sectional study involved 145 university students divided into two groups: users of the university restaurant (group 1, n = 73) and non-users (group 2, n = 72)...
July 28, 2017: Nutrición Hospitalaria: Organo Oficial de la Sociedad Española de Nutrición Parenteral y Enteral
https://www.readbyqxmd.com/read/29092993/the-effect-of-a-single-early-high-dose-vitamin-d-supplement-on-fracture-union-in-patients-with-hypovitaminosis-d-a-prospective-randomised-trial
#18
N Haines, L B Kempton, R B Seymour, M J Bosse, C Churchill, K Hand, J R Hsu, D Keil, J Kellam, N Rozario, S Sims, M A Karunakar
AIMS: To evaluate the effect of a single early high-dose vitamin D supplement on fracture union in patients with hypovitaminosis D and a long bone fracture. PATIENTS AND METHODS: Between July 2011 and August 2013, 113 adults with a long bone fracture were enrolled in a prospective randomised double-blind placebo-controlled trial. Their serum vitamin D levels were measured and a total of 100 patients were found to be vitamin D deficient (< 20 ng/ml) or insufficient (< 30 ng/mL)...
November 2017: Bone & Joint Journal
https://www.readbyqxmd.com/read/29091879/protective-effect-of-the-hydroalcoholic-extract-of-tripodanthus-acutifolius-in-hypercholesterolemic-wistar-rats
#19
Ritiéle Pinto Coelho, Denise Lima Feksa, Patrícia Martinez Oliveira, Angélica Aparecida da Costa Güllich, Bruna Cocco Pilar, Jacqueline da Costa Escobar Piccoli, Vanusa Manfredini
Cardiovascular disease (CVD) are a major public health problem, as they are among the leading causes of mortality worldwide. Tripodanthus acutifolius (TA) is a hemiparasite plant used for medicinal purposes with great antioxidant capacity. However, little is known about its hypolipemic effect. Thus, the aim of this study was to evaluate the effects of the hydroalcoholic extract of Tripodanthus acutifolius leaves in hypercholesterolemic Wistar rats. The animals were divided into: (1) NC (Normocaloric Control); (2) HC (Hypercaloric Control); (3) Oral Simvastatin Suspension 10mg/kg (SIM); (4) TA extract 50mg/kg (TA 50mg/kg) and (5) TA 100mg/kg...
October 26, 2017: Biomedicine & Pharmacotherapy, Biomédecine & Pharmacothérapie
https://www.readbyqxmd.com/read/29091513/apple-cider-vinegar-attenuates-oxidative-stress-and-reduces-the-risk-of-obesity-in-high-fat-fed-male-wistar-rats
#20
Ben Hmad Halima, Gara Sonia, Khlifi Sarra, Ben Jemaa Houda, Ben Slama Fethi, Aouidet Abdallah
Metabolic syndrome is a serious consequence of obesity characterized by increased cardiovascular risk factors such as hypertension, dyslipidemia, and glucose intolerance. While diets enriched with natural antioxidants showed beneficial effects on oxidative stress, blood pressure, and serum lipid composition, diet supplementation with synthetic antioxidants showed contradictive results. Thus, we tested, in this study, whether a daily dosage of Apple Cider Vinegar (ACV) would affect cardiovascular risk factor associated with obesity in high-fat diet (HFD)-induced hyperlipidemic Wistar rats...
November 1, 2017: Journal of Medicinal Food
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