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https://www.readbyqxmd.com/read/28078489/identification-and-profiling-of-conserved-and-novel-micrornas-involved-in-oil-and-oleic-acid-production-during-embryogenesis-in-carya-cathayensis-sarg
#1
Zhengjia Wang, Ruiming Huang, Zhichao Sun, Tong Zhang, Jianqin Huang
MicroRNAs (miRNAs) are important regulators of plant development and fruit formation. Mature embryos of hickory (Carya cathayensis Sarg.) nuts contain more than 70% oil (comprising 90% unsaturated fatty acids), along with a substantial amount of oleic acid. To understand the roles of miRNAs involved in oil and oleic acid production during hickory embryogenesis, three small RNA libraries from different stages of embryogenesis were constructed. Deep sequencing of these three libraries identified 95 conserved miRNAs with 19 miRNA*s, 7 novel miRNAs (as well as their corresponding miRNA*s), and 26 potentially novel miRNAs...
January 11, 2017: Functional & Integrative Genomics
https://www.readbyqxmd.com/read/28077426/nut-consumption-and-lung-cancer-risk-results-from-two-large-observational-studies
#2
Jennifer T Lee, Gabriel Y Lai, Linda M Liao, Amy F Subar, Pier Alberto Bertazzi, Angela C Pesatori, Neal D Freedman, Maria Teresa Landi, Tram Kim Lam
BACKGROUND: Epidemiological evidence on the association between nut consumption and lung cancer risk is limited. METHODS: We investigated this relationship in the Environment And Genetics in Lung cancer Etiology (EAGLE) study, a population-based case-control study, and the National Institutes of Health (NIH) American Association of Retired Persons (AARP) Diet and Health Study, a prospective cohort. We identified 2098 lung cases for EAGLE and 18,533 incident cases in AARP...
January 11, 2017: Cancer Epidemiology, Biomarkers & Prevention
https://www.readbyqxmd.com/read/28073703/development-of-sesame-tolerance-and-cosensitization-of-sesame-allergy-with-peanut-and-tree-nut-allergy-in-children
#3
Karen Thursday S Tuano, Kristin H Dillard, Danielle Guffey, Carla M Davis
No abstract text is available yet for this article.
December 2016: Annals of Allergy, Asthma & Immunology
https://www.readbyqxmd.com/read/28071638/smokeless-tobacco-use-and-perceptions-of-risk-among-students-in-mumbai-municipal-schools
#4
M L Rose, D Chadha, T D Bhutia
INTRODUCTION: Nearly 15% of youth in India use tobacco. However, few studies have explored the use, knowledge, and attitudes of smokeless tobacco use among youth. AIM: To determine the patterns of use as well as knowledge and perceptions of smokeless tobacco among youth in Mumbai attending municipal schools. MATERIALS AND METHODS: A cross-sectional survey was performed among 1053 students in the 8th and 9th grades in 16 municipal schools in Mumbai to determine the knowledge and perceptions about smokeless tobacco products as well as the patterns of use...
April 2016: Indian Journal of Cancer
https://www.readbyqxmd.com/read/28070926/identification-and-implication-of-an-allergenic-pr-10-protein-from-walnut-in-birch-pollen-associated-walnut-allergy
#5
Andrea Wangorsch, Annette Jamin, Jonas Lidholm, Nora Gräni, Claudia Lang, Barbara Ballmer-Weber, Stefan Vieths, Stephan Scheurer
SCOPE: English walnut (Juglans regia) belongs to the most important allergenic tree nuts. Co-sensitization with birch (Betula verrucosa) pollen has been reported. We aimed to identify a walnut allergen homologous to the major birch pollen allergen Bet v 1. METHODS AND RESULTS: A cDNA encoding a Bet v 1-homologous allergen (Jug r 5) in walnut kernels was cloned by RT-PCR. Jug r 5 was expressed in E.coli, purified by column chromatography and characterized by CD-spectroscopy...
January 9, 2017: Molecular Nutrition & Food Research
https://www.readbyqxmd.com/read/28070311/optimization-of-production-and-quality-evaluation-of-maize-based-snack-supplemented-with-soybean-and-tiger-nut-cyperus-esculenta-flour
#6
Olugbenga O Awolu, Olufunmilayo S Omoba, Olumide Olawoye, Modupe Dairo
Optimization of the production and evaluation of the quality of maize-based snack supplemented with soy and tigernut flour was carried out. Experimental design for the composite flour was carried out using optimal design model of response surface methodology. The variables were toasted maize flour (75-85%), soy flour (10-20%), and tigernut flour (5-10%); while the responses were proximate composition and mineral contents. Three blends were selected from optimization results; runs 2, 7, and 11. The functional properties, pasting properties, antioxidant, antinutritional, and amino acid profile of the three blends were evaluated...
January 2017: Food Science & Nutrition
https://www.readbyqxmd.com/read/28069523/a-chronic-increase-of-corticosterone-age-dependently-reduces-systemic-dna-damage-from-oxidation-in-rats
#7
Anders Jorgensen, Otto Kalliokoski, Kristin Forsberg, Katrine Breitenstein, Allan Weimann, Trine Henriksen, Jann Hau, Gitta Wörtwein, Henrik Enghusen Poulsen, Martin Balslev Jorgensen
Stress and depression are associated with an acceleration of brain and bodily aging; effects which have been attributed to chronic elevations of glucocorticoids. We tested the hypothesis that a three week administration of stress-associated levels of corticosterone (CORT, the principal rodent glucocorticoid) would increase systemic and CNS DNA and RNA damage from oxidation; a phenomenon known to be centrally involved in the aging process. We also hypothesized that older individuals would be more sensitive to this effect and that the chronic CORT administration would exacerbate age-related memory decline...
January 7, 2017: Free Radical Biology & Medicine
https://www.readbyqxmd.com/read/28069272/smarcb1-ini1-deficient-sinonasal-carcinoma-shows-methylation-of-rassf1-gene-a-clinicopathological-immunohistochemical-and-molecular-genetic-study-of-a-recently-described-entity
#8
Jan Laco, Marcela Chmelařová, Hana Vošmiková, Kateřina Sieglová, Ivana Bubancová, Pavel Dundr, Kristýna Němejcová, Jaroslav Michálek, Petr Čelakovský, Radovan Mottl, Igor Sirák, Milan Vošmik, Aleš Ryška
The aim of the study was detailed clinicopathological investigation of SMARCB1/INI1-deficient sinonasal carcinomas, including molecular genetic analysis of mutational status and DNA methylation of selected protooncogenes and tumor suppressor genes by means of next generation sequencing (NGS) and methylation-specific multiplex ligation-dependent probe amplification (MS-MLPA). A total of 4/56 (7%) cases of SMARCB1/INI1-deficient carcinomas were detected among 56 sinonasal carcinomas diagnosed over a 19year period using immunohistochemical screening...
October 25, 2016: Pathology, Research and Practice
https://www.readbyqxmd.com/read/28065493/dietary-protein-sources-and-risk-for-incident-chronic-kidney-disease-results-from-the-atherosclerosis-risk-in-communities-aric-study
#9
Bernhard Haring, Elizabeth Selvin, Menglu Liang, Josef Coresh, Morgan E Grams, Natalia Petruski-Ivleva, Lyn M Steffen, Casey M Rebholz
OBJECTIVE: Dietary protein restriction is recommended for patients with moderate to severe renal insufficiency. Long-term data on the relationship between dietary protein sources and risk for incident kidney disease in individuals with normal kidney function are largely missing. This study aimed to assess the association between dietary protein sources and incident chronic kidney disease (CKD). DESIGN: Prospective cohort. SETTING: Atherosclerosis Risk in Communities study participants from 4 US communities...
January 5, 2017: Journal of Renal Nutrition
https://www.readbyqxmd.com/read/28064201/a-method-for-classifying-user-reported-electronic-cigarette-liquid-flavors
#10
Jessica M Yingst, Susan Veldheer, Erin Hammett, Shari Hrabovsky, Jonathan Foulds
BACKGROUND: Along with the growth in popularity of electronic cigarette devices (e-cigs), the variety of e-cig liquids (e-liquid) available to users has also grown. Although some studies have published data about the use of flavored e-liquid, there is no standardized way to group flavors making it difficult to interpret the data and replicate results across studies. The current study describes a method to classify user-reported e-liquid flavors and presents the resulting proportion of users in each flavor group in a large online survey of e-cig users...
January 6, 2017: Nicotine & Tobacco Research: Official Journal of the Society for Research on Nicotine and Tobacco
https://www.readbyqxmd.com/read/28062704/radiosensitization-by-the-atr-inhibitor-azd6738-through-generation-of-acentric-micronuclei
#11
Magnus T Dillon, Holly E Barker, Malin Pedersen, Hind Hafsi, Shreerang A Bhide, Kate L Newbold, Christopher M Nutting, Martin McLaughlin, Kevin J Harrington
AZD6738 is an orally active ATR inhibitor (ATRi) currently in phase I clinical trials. We found in vitro growth inhibitory activity of this ATRi in a panel of human cancer cell lines. We demonstrated radiosensitization by AZD6738 to single radiation fractions in multiple cancer cell lines independent of both p53 and BRCA2 status by the clonogenic assay. Radiosensitization by AZD6738 to clinically relevant doses of fractionated radiation was demonstrated in vitro using a 3D tumor spheroid model and, in vivo, AZD6738 radiosensitized by abrogating the radiation-induced G2 cell-cycle checkpoint and inhibiting homologous recombination...
January 2017: Molecular Cancer Therapeutics
https://www.readbyqxmd.com/read/28060373/small-round-blue-cell-tumors-of-the-sinonasal-tract-a-differential-diagnosis-approach
#12
Lester Dr Thompson
One of the most challenging diagnostic categories within tumors of the sinonasal tract is the small round blue cell tumors. Biopsies are usually small and limited, resulting in considerable diagnostic difficulty for practicing surgical pathologists. These tumors share several overlapping histologic and immunophenotypic findings while also showing considerable variation within and between cases. Specific tumor site of origin, imaging findings, and clinical findings must be combined with the histology and pertinent ancillary studies if the correct diagnosis is to be reached...
January 2017: Modern Pathology: An Official Journal of the United States and Canadian Academy of Pathology, Inc
https://www.readbyqxmd.com/read/28057404/normal-tissue-complication-probability-ntcp-modelling-of-severe-acute-mucositis-using-a-novel-oral-mucosal-surface-organ-at-risk
#13
J A Dean, L C Welsh, K H Wong, A Aleksic, E Dunne, M R Islam, A Patel, P Patel, I Petkar, I Phillips, J Sham, U Schick, K L Newbold, S A Bhide, K J Harrington, C M Nutting, S L Gulliford
AIMS: A normal tissue complication probability (NTCP) model of severe acute mucositis would be highly useful to guide clinical decision making and inform radiotherapy planning. We aimed to improve upon our previous model by using a novel oral mucosal surface organ at risk (OAR) in place of an oral cavity OAR. MATERIALS AND METHODS: Predictive models of severe acute mucositis were generated using radiotherapy dose to the oral cavity OAR or mucosal surface OAR and clinical data...
January 2, 2017: Clinical Oncology: a Journal of the Royal College of Radiologists
https://www.readbyqxmd.com/read/28057106/-dietary-intake-status-of-chinese-lactating-women-during-the-first-month-postpartum-in-2013
#14
Y F Duan, S Jiang, J Wang, L Y Zhao, X H Pang, Y Bi, S A Yin, Z Y Yang
Objective: To assess the dietary intake status of Chinese lactating women during the first month postpartum. Methods: Data were extracted from Chinese National Nutrition and Health Surveillance, children aged 0-5 years and lactating women (2013). A total of 55 counties from 30 provinces in China (excluding the Tibet Autonomous Region) were selected using a multi-stage stratified cluster randomization sampling method. A group of 3 623 lactating women, at 1-6 months after delivery, were investigated in the study...
December 6, 2016: Zhonghua Yu Fang Yi Xue za Zhi [Chinese Journal of Preventive Medicine]
https://www.readbyqxmd.com/read/28056164/analysis-of-sea-almond-terminalia-catappa-cracking-sites-used-by-wild-burmese-long-tailed-macaques-macaca-fascicularis-aurea
#15
Tiago Falótico, Noemi Spagnoletti, Michael Haslam, Lydia V Luncz, Suchinda Malaivijitnond, Michael Gumert
Nut-cracking is shared by all non-human primate taxa that are known to habitually use percussive stone tools in the wild: robust capuchins (Sapajus spp.), western chimpanzees (Pan troglodytes verus), and Burmese long-tailed macaques (Macaca fascicularis aurea). Despite opportunistically processing nuts, Burmese long-tailed macaques predominantly use stone tools to process mollusks in coastal environments. Here, we present the first comprehensive survey of sea almond (Terminalia catappa) nut-cracking sites created by macaques...
January 5, 2017: American Journal of Primatology
https://www.readbyqxmd.com/read/28054652/using-the-target-constituent-removal-combined-with-bioactivity-assay-strategy-to-investigate-the-optimum-arecoline-content-in-charred-areca-nut
#16
Wei Peng, Yu-Jie Liu, Mei-Bian Hu, Dan Yan, Yong-Xiang Gao, Chun-Jie Wu
Charred areca nut (CAN) is used to treat dyspepsia and abdominal distension in children. However, reports revealed that arecoline, the most important active constituent of CAN, possesses potential toxicities. This study was designed to investigate the optimum arecoline content in CAN, using the "target constituent removal combined with bioactivity assay" strategy. Based on PTLC method, we prepared CAN lacking all arecoline (WAC-100R) and a series of different ratios of arecoline-removed CAN samples (WAC-Rx)...
January 5, 2017: Scientific Reports
https://www.readbyqxmd.com/read/28050496/the-insight-for-initiation-and-maintenance-of-areca-nut-chewing-habit-and-its-effects-on-oral-health-status-among-school-age-population-in-western-rajasthan-india
#17
Abhishek Singhvi, Ashish Joshi, Neeta Bagul, Sanya Bhatia, Gurdeep Singh, Rajkumari Gupta
INTRODUCTION: Areca nut is highly carcinogenic according to International Agency for Research on Cancer (IARC). Its usage is continuously increasing in children and adolescents in India. AIM: The aim of the study was to understand the reasons for the development of the areca nut chewing habit at early age. MATERIALS AND METHODS: A total of 2846 subjects were surveyed from rural government schools between ages of 4 to18 years in Western Rajasthan, India...
November 2016: Journal of Clinical and Diagnostic Research: JCDR
https://www.readbyqxmd.com/read/28048625/tu-h-206-02-novel-linearly-filled-derenzo-pet-phantom-design
#18
S Graves, B Cox, M Farhoud, H Valdovinos, J Jeffery, K Eliceiri, T Barnhart, R Nickles
PURPOSE: To design a linearly-filled Derenzo positron emission tomography (PET) phantom, eliminating the extraneous radioisotope volumes in a conventional reservoir-type design. This activity reduction combined with the elimination of bubbles in smaller phantom channels would significantly reduce personnel dose, radioisotope cost, and would improve image quality by reducing out-of-slice activity scatter. METHODS: A computer-aided design (CAD) was created of a modular Derenzo phantom consisting of three phantom layers with gaskets between the layers...
June 2016: Medical Physics
https://www.readbyqxmd.com/read/28047324/tu-fg-201-05-varian-mpc-as-a-statistical-process-control-tool
#19
A Carver, C Rowbottom
PURPOSE: Quality assurance in radiotherapy requires the measurement of various machine parameters to ensure they remain within permitted values over time. In Truebeam release 2.0 the Machine Performance Check (MPC) was released allowing beam output and machine axis movements to be assessed in a single test. We aim to evaluate the Varian Machine Performance Check (MPC) as a tool for Statistical Process Control (SPC). METHODS: Varian's MPC tool was used on three Truebeam and one EDGE linac for a period of approximately one year...
June 2016: Medical Physics
https://www.readbyqxmd.com/read/28036057/green-tea-and-other-tea-polyphenols-effects-on-sebum-production-and-acne-vulgaris
#20
REVIEW
Suzana Saric, Manisha Notay, Raja K Sivamani
Polyphenols are antioxidant molecules found in many foods including nuts, fruits, vegetables, chocolate, wine, and tea. Polyphenols have antimicrobial, anti-inflammatory, and antineoplastic properties. Recent studies suggest that tea polyphenols may be used for reducing sebum production in the skin and for treatment of acne vulgaris. This review examines the evidence for use of topically and orally ingested tea polyphenols against sebum production and for acne treatment and prevention. The PubMed database was searched for studies on tea polyphenols, sebum secretion, and acne vulgaris...
December 29, 2016: Antioxidants (Basel, Switzerland)
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