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Nutritional disease

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https://www.readbyqxmd.com/read/29924835/association-between-dry-eye-symptoms-and-suicidal-ideation-in-a-korean-adult-population
#1
Sun-Bi Um, Hyungseon Yeom, Na Hyun Kim, Hyeon Chang Kim, Hyung Keun Lee, Il Suh
PURPOSE: This study assessed the association of dry eyes with depression and suicidal ideation in a Korean adult population. METHODS: Data from 16408 participants (6972 men and 9436 women) aged ≥ 19 years included in the fifth Korea National Health and Nutrition Examination Survey, conducted from 2010-2012, were analyzed. For dry eyes, surveys of previous diagnosis of dry eye disease (DED) by an ophthalmologist and experience of subjective dry eye symptoms were separately used...
2018: PloS One
https://www.readbyqxmd.com/read/29924327/higher-longitudinal-milk-intakes-are-associated-with-increased-height-in-a-birth-cohort-followed-for-17-years
#2
Teresa A Marshall, Alexandra M Curtis, Joseph E Cavanaugh, John J Warren, Steven M Levy
Background: Height is an indicator of nutritional status; linear growth faltering has recognized consequences for cognitive, emotional, and chronic disease risk. Although height is routinely studied in developing countries, less attention is given to height in the United States. Objective: The objective of this study was to identify longitudinal associations between childhood and adolescent beverage intakes, nutrient adequacy, or energy intake and height in a birth cohort...
June 19, 2018: Journal of Nutrition
https://www.readbyqxmd.com/read/29924298/metabolic-signature-of-healthy-lifestyle-and-its-relation-with-risk-of-hepatocellular-carcinoma-in-a-large-european-cohort
#3
Nada Assi, Marc J Gunter, Duncan C Thomas, Michael Leitzmann, Magdalena Stepien, Véronique Chajès, Thierry Philip, Paolo Vineis, Christina Bamia, Marie-Christine Boutron-Ruault, Torkjel M Sandanger, Amaia Molinuevo, Hendriek Boshuizen, Anneli Sundkvist, Tilman Kühn, Ruth Travis, Kim Overvad, Elio Riboli, Augustin Scalbert, Mazda Jenab, Vivian Viallon, Pietro Ferrari
Background: Studies using metabolomic data have identified metabolites from several compound classes that are associated with disease-related lifestyle factors. Objective: In this study, we identified metabolic signatures reflecting lifestyle patterns and related them to the risk of hepatocellular carcinoma (HCC) in the European Prospective Investigation into Cancer and Nutrition (EPIC) cohort. Design: Within a nested case-control study of 147 incident HCC cases and 147 matched controls, partial least squares (PLS) analysis related 7 modified healthy lifestyle index (HLI) variables (diet, BMI, physical activity, lifetime alcohol, smoking, diabetes, and hepatitis) to 132 targeted serum-measured metabolites and a liver function score...
June 18, 2018: American Journal of Clinical Nutrition
https://www.readbyqxmd.com/read/29923978/correlations-between-health-promoting-lifestyle-and-health-related-quality-of-life-among-elderly-people-with-hypertension-in-hengyang-hunan-china
#4
Jianzhi Li, Jiangdong Yu, Xi Chen, Xuewen Quan, Lan Zhou
Hypertension is considered as an important public health problem in developed and developing countries. The disease is closely associated with health-promoting lifestyle (HPL), and it seems that HPL plays an important role in improving health-related quality of life (HRQOL). This cross-sectional study is to investigate the effects of health-promoting lifestyle (HPL) on health-related quality of life in elderly people with hypertension from a community health service center in Hengyang, Hunan, PR China.Totally 530 elderly patients with hypertension from the community health service center were included in this study, who were asked to fill in a questionnaire (504 patients responded)...
June 2018: Medicine (Baltimore)
https://www.readbyqxmd.com/read/29923538/obesity-and-serum-uric-acid-in-secondary-school-age-students-of-srinagarindra-the-princess-mother-school-phayao-thailand
#5
Wanpen Suttikomin, Preeya Leelahagul, Suphawan Khamvang, Chamnong Chaimongkol, Nanticha Chaiwut
Background: Obesity and hyperuricemia are the precipitating factors of multiple disease processes. Studies on the relationship between obesity and hyperuricemia in Thai adolescents are limited. Objective: The objective is to investigate the gender differences in obesity and serum uric acid as well as the relationship between obesity and serum uric acid levels in secondary school-age students. Methods: A cross-sectional study conducted among 689 secondary school-age students; 313 boys and 376 girls...
April 2018: Indian Journal of Public Health
https://www.readbyqxmd.com/read/29923483/enterocutaneous-fistula-treatment-case-report-and-review-of-the-literature
#6
REVIEW
M Assenza, D Rossi, I De Gruttola, C Ballanti
OBJECTIVE: The aim of this work is to evaluate the treatment strategies for a common major surgery complication like the enterocutaneous fistula (ECFs). Since there is not any standard treatment for this common disease and since new therapies, like NPWT and fibrin sealants, have come up a review of all their indications seemed useful. We also present two clinical cases treated in this way. PATIENTS AND METHODS: A research was made in the principle databases such as: "Cochrane", "Pubmed", "Google Scholar" and "Google" using the following Key words "enterocutaneous fistula", "fibrin glue", "VAC", "VAC treatment", "fistula", "conservative treatment", "surgery" and using the MESH Function to search similar key words and expand the research...
May 2018: Il Giornale di Chirurgia
https://www.readbyqxmd.com/read/29922826/differences-in-obesity-prevalence-by-demographics-and-urbanization-in-us-children-and-adolescents-2013-2016
#7
Cynthia L Ogden, Cheryl D Fryar, Craig M Hales, Margaret D Carroll, Yutaka Aoki, David S Freedman
Importance: Differences in childhood obesity by demographics and urbanization have been reported. Objective: To present data on obesity and severe obesity among US youth by demographics and urbanization and to investigate trends by urbanization. Design, Setting, and Participants: Measured weight and height among youth aged 2 to 19 years in the 2001-2016 National Health and Nutrition Examination Surveys, which are serial, cross-sectional, nationally representative surveys of the civilian, noninstitutionalized population...
June 19, 2018: JAMA: the Journal of the American Medical Association
https://www.readbyqxmd.com/read/29922101/metabolic-syndrome-in-adults-with-a-history-of-juvenile-arthritis
#8
Sangeeta Sule, Kevin Fontaine
Objective: The objective of this study was to determine the risk of obesity and metabolic syndrome in adults with a history of juvenile arthritis (JA). Methods: Using the National Health and Nutrition Examination Survey (NHANES), we compared the characteristics of respondents with arthritis (JA vs rheumatoid arthritis [RA]) to those of the control group without arthritis. We used logistic regression analyses, controlling for age, race, and gender, to determine the ORs for metabolic syndrome...
2018: Open Access Rheumatology: Research and Reviews
https://www.readbyqxmd.com/read/29921957/hepatokin1-is-a-biochemistry-based-model-of-liver-metabolism-for-applications-in-medicine-and-pharmacology
#9
Nikolaus Berndt, Sascha Bulik, Iwona Wallach, Tilo Wünsch, Matthias König, Martin Stockmann, David Meierhofer, Hermann-Georg Holzhütter
The epidemic increase of non-alcoholic fatty liver diseases (NAFLD) requires a deeper understanding of the regulatory circuits controlling the response of liver metabolism to nutritional challenges, medical drugs, and genetic enzyme variants. As in vivo studies of human liver metabolism are encumbered with serious ethical and technical issues, we developed a comprehensive biochemistry-based kinetic model of the central liver metabolism including the regulation of enzyme activities by their reactants, allosteric effectors, and hormone-dependent phosphorylation...
June 19, 2018: Nature Communications
https://www.readbyqxmd.com/read/29921799/nutritional-requirements-of-lung-transplant-recipients-challenges-and-considerations
#10
REVIEW
Valerie Jomphe, Larry C Lands, Genevieve Mailhot
An optimal nutritional status is associated with better post-transplant outcomes and survival. Post-lung transplant nutrition management is however particularly challenging as lung recipients represent a very heterogeneous group of patients in terms of age, underlying diseases, weight status and presence of comorbidities. Furthermore, the post-transplant period encompasses several stages characterized by physiological and pathophysiological changes that affect nutritional status of patients and necessitate tailored nutrition management...
June 19, 2018: Nutrients
https://www.readbyqxmd.com/read/29921793/endoplasmic-reticulum-stress-in-metabolic-disorders
#11
REVIEW
Rose Ghemrawi, Shyue-Fang Battaglia-Hsu, Carole Arnold
Metabolic disorders have become among the most serious threats to human health, leading to severe chronic diseases such as obesity, type 2 diabetes, and non-alcoholic fatty liver disease, as well as cardiovascular diseases. Interestingly, despite the fact that each of these diseases has different physiological and clinical symptoms, they appear to share certain pathological traits such as intracellular stress and inflammation induced by metabolic disturbance stemmed from over nutrition frequently aggravated by a modern, sedentary life style...
June 19, 2018: Cells
https://www.readbyqxmd.com/read/29921537/the-oligopeptide-abc-transporter-oppa4-negatively-regulates-the-virulence-factor-ospc-production-of-the-lyme-disease-pathogen
#12
Bibi Zhou, Youyun Yang, Tong Chen, Yongliang Lou, X Frank Yang
Borrelia burgdorferi sensu lato, the agent of Lyme disease, exists in nature through a complex enzootic life cycle that involves both ticks and mammals. The B. burgdorferi genome encodes five Oligopeptide ABC transporters (Opp) that are predicted to be involve in transport of various nutrients. Previously, it was reported that OppA5 is important for the optimal production of OspC, a major virulence factor of B. burgdorferi. In this study, possible role of another Oligopeptide ABC transporter, OppA4 in ospC expression was investigated by construction of an oppA4 deletion mutant and the complemented strain...
June 15, 2018: Ticks and Tick-borne Diseases
https://www.readbyqxmd.com/read/29921470/ttc7a-mutation-must-be-considered-in-patients-with-repeated-intestinal-atresia-associated-with-early-inflammatory-bowel-disease-two-new-case-reports-and-a-literature-review
#13
J Fayard, S Collardeau, Y Bertrand, M-P Cordier, C Malcus, R Dubois, P-Y Mure, G de Saint Basile, T Louazon, B Rohmer, A Lachaux, R Duclaux, N Peretti
TTC7A mutations cause multiple neonatal intestinal atresias with early inflammatory bowel disease and severe combined immunodeficiency. There are no treatment protocols for this rare disease. Two new cases are described for which radical early treatment measures - total enterectomy, home parenteral nutrition, immunoglobulin therapy and intravenous antibiotic prophylaxis - have allowed both patients to develop optimally.
June 16, 2018: Archives de Pédiatrie: Organe Officiel de la Sociéte Française de Pédiatrie
https://www.readbyqxmd.com/read/29921412/superoxide-dismutase-3-protects-mesenchymal-stem-cells-through-enhanced-autophagy-and-regulation-of-foxo3a-trafficking
#14
Gaurav Agrahari, Shyam Kishor Sah, Tae-Yoon Kim
Therapeutic applications of mesenchymal stem cells (MSCs) are limited due to their early death within the first few days of transplantation. Therefore, to improve the efficacy of cell-based therapies, it is necessary to manipulate MSCs so that they can resist various stresses imposed by the microenvironment. Moreover, the role of superoxide dismutase 3 (SOD3) in regulating such survival under different stress conditions remain elusive. In this study, we overexpressed SOD3 in MSCs (SOD3-MSCs) and evaluated its effect under serum starvation conditions...
June 20, 2018: BMB Reports
https://www.readbyqxmd.com/read/29921329/metabolomic-signatures-distinguish-the-impact-of-formula-carbohydrates-on-disease-outcome-in-a-preterm-piglet-model-of-nec
#15
Lee Call, Barbara Stoll, Berthe Oosterloo, Nadim Ajami, Fariha Sheikh, Anja Wittke, Rosaline Waworuntu, Brian Berg, Joseph Petrosino, Oluyinka Olutoye, Douglas Burrin
BACKGROUND: Major risk factors for necrotizing enterocolitis (NEC) include premature birth and formula feeding in the context of microbial colonization of the gastrointestinal tract. We previously showed that feeding formula composed of lactose vs. corn syrup solids protects against NEC in preterm pigs; however, the microbial and metabolic effects of these different carbohydrates used in infant formula has not been explored. OBJECTIVE: Our objective was to characterize the effects of lactose- and corn syrup solid-based formulas on the metabolic and microbial profiles of preterm piglets and to determine whether unique metabolomic or microbiome signatures correlate with severity or incidence of NEC...
June 19, 2018: Microbiome
https://www.readbyqxmd.com/read/29920911/predictors-of-complications-and-mortality-following-left-colectomy-with-primary-stapled-anastomosis-for-cancer-results-of-a-multicentric-study-with-1111-patients
#16
Gianluca Pellino, Matteo Frasson, Alvaro García-Granero, Pablo Granero-Castro, José Luis Ramos Rodríguez, Blas Flor-Lorente, José Bargallo Berzosa, Natalia Alonso Hernández, Francisco Javier Labrador Vallverdú, Pedro Antonio Parra Baños, Guillermo Ais Conde, Eduardo Garcia-Granero
AIM: Reports detailing the morbidity-mortality after left colectomy are sparse and do not allow to draw definitive conclusions. We aimed to identify risk factors for anastomotic leak, perioperative mortality and complications following left colectomy for colonic malignancies. METHOD: We undertook a STROBE-compliant analysis of left colectomies included in the National prospective online database. Forty-two variables were analyzed as potential independent risk factors for anastomotic leak, post-operative morbidity and mortality...
June 19, 2018: Colorectal Disease: the Official Journal of the Association of Coloproctology of Great Britain and Ireland
https://www.readbyqxmd.com/read/29920783/food-intake-and-energy-expenditure-in-growing-cats-with-and-without-a-predisposition-to-overweight
#17
Vivien Ghielmetti, Brigitta Wichert, Simon Rüegg, Diana Frey, Annette Liesegang
Overweight and obesity are multifactorial diseases caused by an imbalance in energy metabolism. An underlying genetic predisposition is often a factor in these conditions. In the cat breeding family of the Institute of Animal Nutrition at the Vetsuisse Faculty, University of Zurich, a segregating overweight phenotype with a genetic contribution was observed. From this breeding family, 26 kittens were followed from birth up to 8 months of age. During this time, food intake was measured using an automatic feeding station, and energy expenditure was investigated using indirect calorimetry at the ages of 4 and 6 months...
June 19, 2018: Journal of Animal Physiology and Animal Nutrition
https://www.readbyqxmd.com/read/29920701/sarcopenia-is-associated-with-the-risk-of-significant-liver-fibrosis-in-metabolically-unhealthy-subjects-with-chronic-hepatitis-b
#18
E Han, Y-H Lee, B K Kim, J Y Park, D Y Kim, S H Ahn, B-W Lee, E S Kang, B-S Cha, K-H Han, S U Kim
BACKGROUND: Sarcopenia is significantly associated with the degree of liver fibrosis. This study investigated the influence of sarcopenia on liver fibrosis in individuals with chronic hepatitis B. METHODS: Data from the Korean National Health and Nutrition Examination Surveys 2008-2011 were analysed. The sarcopenia index (total appendicular skeletal muscle mass [kg]/body mass index [kg/m2 ]) was calculated using dual-energy X-ray absorptiometry. Sarcopenia was defined as the lowest quintile sarcopenia index value (cut-offs: 0...
June 19, 2018: Alimentary Pharmacology & Therapeutics
https://www.readbyqxmd.com/read/29920633/institutional-experience-with-spiral-intestinal-lengthening-and-tailoring
#19
Riccardo Coletta, Bashar Aldeiri, Antonino Morabito
AIM:  The aim of this study was to report our initial experience using spiral intestinal lengthening and tailoring (SILT) technique in selected cases of short bowel syndrome (SBS). MATERIALS AND METHODS:  We analyzed all cases of SBS underwent SILT in our unit since the introduction of the procedure in 2012. We retrospectively analyzed patients' demographics, pre- and postprocedure bowel length, surgical complications, and postoperative parenteral nutrition (PN) requirements...
June 19, 2018: European Journal of Pediatric Surgery
https://www.readbyqxmd.com/read/29920555/metabolic-syndrome-prevalence-and-its-risk-factors-among-adults-in-china-a-nationally-representative-cross-sectional-study
#20
Yaru Li, Liyun Zhao, Dongmei Yu, Zhihong Wang, Gangqiang Ding
OBJECTIVES: The aim of this study was to examine sex disparity in metabolic syndrome prevalence and its risk factors among Chinese adults. METHODS: Using the 2010-2012 China National Nutrition and Health Survey (CNNHS), a nationally representative cross-sectional study on nutrition and non-communicable chronic diseases, a total of 98,042 participants aged 18 years and older were included in the analysis. Dietary information was collected with a food frequency questionnaire (FFQ)...
2018: PloS One
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