keyword
MENU ▼
Read by QxMD icon Read
search

hnc

keyword
https://www.readbyqxmd.com/read/28102098/a-randomized-double-blind-placebo-controlled-trial-of-fruit-and-vegetable-concentrates-on-intermediate-biomarkers-in-head-and-neck-cancer
#1
Mridul Datta, Edward G Shaw, Glenn J Lesser, L Douglas Case, Mara Z Vitolins, Charles Schneider, Bart Frizzell, Christopher Sullivan, Mark Lively, Elizabeth Franzmann, Jennifer J Hu
BACKGROUND: Head and neck cancer (HNC) patients are at an increased risk for developing second primary tumors (SPTs). Diets rich in fruits and vegetables (FVs) may lower HNC risk. FV concentrates may offer a potential alternative to increasing FV intake. METHODS: We conducted a randomized, double-blind, placebo-controlled trial to evaluate whether Juice PLUS+ (JP; a commercial product with multiple FV concentrates) has an effect on p27 and Ki-67, biomarkers associated with the risk of SPTs...
January 1, 2017: Integrative Cancer Therapies
https://www.readbyqxmd.com/read/28095814/risk-factors-for-aspiration-pneumonia-after-definitive-chemoradiotherapy-or-bio-radiotherapy-for-locally-advanced-head-and-neck-cancer-a-monocentric-case-control-study
#2
Sadayuki Kawai, Tomoya Yokota, Yusuke Onozawa, Satoshi Hamauchi, Akira Fukutomi, Hirofumi Ogawa, Tsuyoshi Onoe, Tetsuro Onitsuka, Takashi Yurikusa, Akiko Todaka, Takahiro Tsushima, Yukio Yoshida, Yosuke Kito, Keita Mori, Hirofumi Yasui
BACKGROUND: Chemoradiotherapy (CRT) and bio-radiotherapy (BRT) are recognized as standard therapies for head and neck cancer (HNC). Aspiration pneumonia after CRT or BRT is a common late adverse event. Our aim in this study was to evaluate the cause-specific incidence of aspiration pneumonia after CRT or BRT and to identify its clinical risk factors. METHODS: We performed a retrospective analysis of 305 patients with locally advanced HNC treated by CRT or BRT between August 2006 and April 2015...
January 17, 2017: BMC Cancer
https://www.readbyqxmd.com/read/28095728/dental-prophylaxis-and-osteoradionecrosis
#3
C T Chang, S P Liu, C H Muo, C H Tsai, Y F Huang
The aim of this study was to investigate the association of different dental prophylactic modalities and osteoradionecrosis (ORN) and determine the risk of ORN under different timing periods of scaling, with the use chlorhexidine mouth rinse after surgery and with different strategies of fluoride gel application in head and neck cancer (HNC) participants. A cohort of 18,231 HNC participants, including 941 ORN patients and 17,290 matched control cases, were enrolled from a Longitudinal Health Insurance Database for Catastrophic Illness Patients (LHID-CIP) in Taiwan...
January 1, 2017: Journal of Dental Research
https://www.readbyqxmd.com/read/28081302/education-and-support-needs-in-patients-with-head-and-neck-cancer-a-multi-institutional-survey
#4
Joe Jabbour, Chris Milross, Puma Sundaresan, Ardalan Ebrahimi, Heather L Shepherd, Haryana M Dhillon, Gary Morgan, Bruce Ashford, Muzib Abdul-Razak, Eva Wong, Michael Veness, Carsten E Palme, Cate Froggatt, Ruben Cohen, Rafael Ekmejian, Jessica Tay, David Roshan, Jonathan R Clark
BACKGROUND: Head and neck cancer (HNC) encompasses a diverse group of tumors, and thus providing appropriate and tailored information to patients before, during, and after treatment is a challenge. The objective of the current study was to characterize the experience and unmet needs of patients with HNC with regard to information and support provision. METHODS: A 28-question, cross-sectional survey was completed by patients treated for HNC at 1 of 4 institutions in New South Wales, Australia (Chris O'Brien Lifehouse and Liverpool, Westmead, and Wollongong hospitals)...
January 12, 2017: Cancer
https://www.readbyqxmd.com/read/28079435/bioelectrical-impedance-analysis-of-head-and-neck-cancer-patients-at-presentation
#5
Marie Lundberg, Pia Nikander, Katja Tuomainen, Helena Orell-Kotikangas, Antti Mäkitie
CONCLUSION: Finnish head and neck cancer (HNC) patients show signs of severe malnutrition already at presentation, measured by bioelectric impedance analysis (BIA). BIA may be a practical method to detect malnutrition, analyze body composition, and to identify high-risk patients in this population. OBJECTIVES: BIA is a validated method for evaluating body composition and detecting malnutrition. Low phase angle (PA) is associated with increased mortality and morbidity...
January 12, 2017: Acta Oto-laryngologica
https://www.readbyqxmd.com/read/28079429/association-between-late-effects-assessed-by-physicians-and-quality-of-life-reported-by-head-and-neck-cancer-survivors
#6
Rikke Daugaard, Trille Kjaer, Christoffer Johansen, Jane Christiansen, Elo Andersen, Anni L Nielsen, Susanne O Dalton
BACKGROUND: Many survivors of head-and-neck cancer (HNC) suffer from late effects. Their overall quality of life deteriorates during treatment, followed by a slow recovery up to five years after treatment. We examined the association between the severity of physician-assessed late effects and the health-related quality of life (HRQoL) reported by survivors of HNC. MATERIAL AND METHODS: The analysis was based on data collected during follow-up for 136 survivors of cancer in the oral cavity, pharynx, larynx, or salivary glands...
January 12, 2017: Acta Oncologica
https://www.readbyqxmd.com/read/28071621/assessment-of-the-sociodemographic-characteristics-and-efficacy-of-screening-for-oral-head-and-neck-potential-malignant-lesions-in-apparently-healthy-adults-in-jos-nigeria
#7
A A Adoga, O A Silas, J P Yaro, E T Okwori, A A Iduh, C J Mgbachi
BACKGROUND: The efficacy of screening for oral, head and neck cancers (HNCs) in adequately identifying high-risk groups is controversial. OBJECTIVES: This study aims to review our experience with a free oral, HNC-screening program to determine the sociodemographic characteristics of the participants and the effectiveness of this program to improve future programs. MATERIALS AND METHODS: A prospective cross-sectional survey of participants in a free oral, HNC screening exercise was performed in the years 2009, 2012, and 2013...
April 2016: Indian Journal of Cancer
https://www.readbyqxmd.com/read/28057599/aspirin-plus-sorafenib-potentiates-cisplatin-cytotoxicity-in-resistant-head-and-neck-cancer-cells-through-xct-inhibition
#8
Jong-Lyel Roh, Eun Hye Kim, Hyejin Jang, Daiha Shin
The nonsteroidal anti-inflammatory drug aspirin and the multikinase inhibitor sorafenib have both shown experimental and clinical anticancer activities. The present study investigated whether aspirin and sorafenib synergize to potentiate cisplatin treatment in resistant head and neck cancer (HNC) cells. The effects of aspirin, sorafenib and cisplatin, and combinations thereof were assessed by measuring cell viability, death, glutathione (GSH) and reactive oxygen species (ROS) levels, protein and mRNA expression, genetic inhibition and overexpression of cystine-glutamate antiporter (xCT) and tumor xenograft mouse models...
January 3, 2017: Free Radical Biology & Medicine
https://www.readbyqxmd.com/read/28049332/solvation-of-mg-in-helium-4-are-there-meta-stable-mg-dimers
#9
Eckhard Krotscheck, Robert E Zillich
Experiments with (4)He nanodroplets doped with Mg atoms were interpreted as the observation of the formation of weakly bound magnesium complexes. We present results for single Mg and Mg dimer solvation using the hypernetted chain/Euler-Lagrange (HNC-EL) method as well as path integral Monte Carlo simulations. We find that the phonon-mediated, indirect Mg-Mg interaction adds an oscillatory component to the direct Mg-Mg interaction. We undertake a step-by-step examination of the ingredients of the calculation of the phonon-induced interaction, comparing the results of semi-analytic HNC-EL calculations for bulk and single impurity results with experiments as well as Monte Carlo data...
December 28, 2016: Journal of Chemical Physics
https://www.readbyqxmd.com/read/28048452/we-fg-202-07-an-mri-based-approach-to-quantify-radiation-induced-normal-tissue-injury-applied-to-trismus-after-head-and-neck-cancer-radiotherapy
#10
M Thor, N Tyagi, V Hazoglou, Z Saleh, N Riaz, N Lee, J Deasy
PURPOSE: The aim of this study was to investigate if quantitative MRI-derived metrics from four masticatory muscles could explain mouth-opening limitation/trismus following intensity-modulated radiotherapy (IMRT) for head and neck cancer (HNC). METHODS: Fifteen intensity-based MRI metrics were derived from the masseter, lateral and medial pterygoid, and temporalis in T1-weighted scans acquired pre- and post gadolinium injection (T1Pre, T1Post) of 16, of in total 20, patients (8 symptomatic; 8 asymptomatic age/sex/tumor location-matched) treated with IMRT to 70 Gy (median) for HNC in 2005-2009...
June 2016: Medical Physics
https://www.readbyqxmd.com/read/28047669/we-h-brc-07-validation-of-a-commercial-atlas-based-auto-segmentation-package-for-automated-contour-quality-control
#11
S Berry, K Jedruszczuk, H Veeraraghavan, A Apte, Z Saleh, M Hunt
PURPOSE: To investigate whether a commercial atlas based auto-segmentation (ABAS) package can be used for automated review and quality control (QC) of physician segmentations, and if so, to determine action levels for future clinical implementation. METHODS: 42 head and neck cancer (HNC) patient plan CT scans with manually defined expert physician organ at risk (OAR) segmentations were retrospectively identified. Five representative patients were selected as ABAS models and were subsequently applied to each of the remaining 37 studies, resulting in 5 auto-segmentations (AS) per patient...
June 2016: Medical Physics
https://www.readbyqxmd.com/read/28047431/su-f-r-51-radiomics-in-ct-perfusion-maps-of-head-and-neck-cancer
#12
M Nesteruk, O Riesterer, R Bundschuh, P Veit-Haibach, M Huellner, G Studer, S Stieb, S Glatz, M Pruschy, M Guckenberger, S Tanadini-Lang
PURPOSE: The aim of this study was to test the predictive value of radiomics features of CT perfusion (CTP) for tumor control, based on a preselection of radiomics features in a robustness study. METHODS: 11 patients with head and neck cancer (HNC) and 11 patients with lung cancer were included in the robustness study to preselect stable radiomics parameters. Data from 36 HNC patients treated with definitive radiochemotherapy (median follow-up 30 months) was used to build a predictive model based on these parameters...
June 2016: Medical Physics
https://www.readbyqxmd.com/read/28046681/su-f-j-192-a-quick-and-effective-method-to-validate-patient-s-daily-setup-and-geometry-changes-prior-to-proton-treatment-delivery-based-on-water-equivalent-thickness-projection-imaging-wetpi-for-head-neck-cancer-hnc-patient
#13
G Liu, A Qin, J Zhang, X Li, J Zhou, D Yan, B Teo, P Chen, D Krauss, P Kabolizadeh, T Guerrero, C Stevens, J Liang, X Ding
PURPOSE: With the implementation of Cone-beam Computed-Tomography (CBCT) in proton treatment, we introduces a quick and effective tool to verify the patient's daily setup and geometry changes based on the Water-Equivalent-Thickness Projection-Image(WETPI) from individual beam angle. METHODS: A bilateral head neck cancer(HNC) patient previously treated via VMAT was used in this study. The patient received 35 daily CBCT during the whole treatment and there is no significant weight change...
June 2016: Medical Physics
https://www.readbyqxmd.com/read/28046611/su-f-t-205-effectiveness-of-robust-treatment-planning-to-account-for-inter-fractional-variation-in-intensity-modulated-proton-therapy-for-head-neck-cancer
#14
X Li, J Zhang, A Qin, J Liang, J Zhou, D Yan, P Chen, D Krauss, X Ding
PURPOSE: To evaluate the potential benefits of robust optimization in intensity modulated proton therapy(IMPT) treatment planning to account for inter-fractional variation for Head Neck Cancer(HNC). METHODS: One patient with bilateral HNC previous treated at our institution was used in this study. Ten daily CBCTs were selected. The CT numbers of the CBCTs were corrected by mapping the CT numbers from simulation CT via Deformable Image Registration. The planning target volumes(PTVs) were defined by a 3mm expansion from clinical target volumes(CTVs)...
June 2016: Medical Physics
https://www.readbyqxmd.com/read/28046569/we-ab-207b-08-exploring-and-refining-the-quantec-guideline-to-reduce-severe-hyposalivation-following-imrt-for-head-and-neck-cancer
#15
M Thor, A Owosho, H Rosenburg, S Yom, J Oh, N Riaz, J Tsai, N Lee, J Huryn, C Estilo, J Deasy
PURPOSE: The aim of this study was to investigate the usefulness of the QUANTEC guideline to prevent xerostomia after intensity-modulated radiotherapy (IMRT) for head and neck cancer (HNC) with respect to follow-up time. In addition, we explored alternative guidelines to further reduce xerostomia. METHODS: The QUANTEC guideline suggests a mean dose to the contralateral (Dmeancontra) parotid<20 Gy, or Dmeancontra and Dmean to the ipsilateral parotid (Dmeanipsi)<25 Gy...
June 2016: Medical Physics
https://www.readbyqxmd.com/read/28045631/head-and-neck-cancer
#16
Peter F Svider, Michael A Blasco, S Naweed Raza, Mahdi Shkoukani, Ammar Sukari, George H Yoo, Adam J Folbe, Ho-Sheng Lin, Andrew M Fribley
Despite a considerable expansion in our therapeutic repertoire for management of other malignancies, mortality from head and neck cancer (HNC) has not significantly improved in recent decades. Upon normalizing National Institutes of Health-awarded R01 and R01-equivalent grants by incidence, thyroid cancer ($214) and HNC ($1329) received the fewest funding dollars. Upon adjusting funding totals by mortality, HNC was 7th out of 9 cancers evaluated ($6138). These findings highlight HNC as an underfunded disease versus other cancers...
January 2017: Otolaryngology—Head and Neck Surgery
https://www.readbyqxmd.com/read/28039504/end-of-life-care-for-head-and-neck-cancer-patients-a-population-based-study
#17
Tzu-Lung Kuo, Ching-Heng Lin, Rong-San Jiang, Ting-Ting Yen, Chen-Chi Wang, Kai-Li Liang
PURPOSE: Head and neck cancers (HNCs) usually present a poor prognosis and cause high morbidity rates. Recent surveys have demonstrated that HNC incidence rates are still on the increase in many countries. Our study objective was to assess the end-of-life care for patients with HNCs in Taiwan. METHODS: Data was retrieved from Taiwan's National Health Insurance Research Database, where we identified patients who had been diagnosed with HNCs from January 1997 to December 2010...
December 30, 2016: Supportive Care in Cancer: Official Journal of the Multinational Association of Supportive Care in Cancer
https://www.readbyqxmd.com/read/28025390/prevalence-of-hpv-infection-in-racial-ethnic-subgroups-of-head-and-neck-cancer-patients
#18
Camille Ragin, Jeffrey C Liu, Gieira Jones, Olubunmi Shoyele, Bukola Sowunmi, Rachel Kennett, Harry J M Groen, Denise Gibbs, Elizabeth Blackman, Michael Esan, Margaret S Brandwein, Karthik Devarajan, Francesco Bussu, Rebecca Chernock, Chih-Yen Chien, Marc A Cohen, El-Mofty Samir, Suzuki Mikio, Gypsyamber D'Souza, Pauline Funchain, Charis Eng, Susanne M Gollin, Angela Hong, Yuh-S Jung, Maximilian Krüger, James Lewis, Patrizia Morbini, Santo Landolfo, Massimo Rittà, Jos Straetmans, Krisztina Szarka, Ruth Tachezy, Francis P Worden, Deborah Nelson, Samuel Gathere, Emanuela Taioli
The landscape of HPV infection in racial/ethnic subgroups of head and neck cancer (HNC) patients has not been evaluated carefully. In this study, a meta-analysis examined the prevalence of HPV in HNC patients of African ancestry. Additionally, a pooled analysis of subject-level data was also performed to investigate HPV prevalence and patterns of p16 (CDNK2A) expression amongst different racial groups. Eighteen publications (N = 798 Black HNC patients) were examined in the meta-analysis, and the pooled analysis included 29 datasets comprised of 3,129 HNC patients of diverse racial/ethnic background...
December 26, 2016: Carcinogenesis
https://www.readbyqxmd.com/read/28024728/laryngeal-tumours-and-radiotherapy-dose-to-the-cricopharyngeus-are-predictive-of-death-from-aspiration-pneumonia
#19
Jolyne O'Hare, Julia Maclean, Michal Szczesniak, Rashmi Gupta, Peter Wu, Harry Quon, Ian Cook, Peter Graham
OBJECTIVES: Aspiration pneumonia is an under-reported treatment sequelae following radiotherapy for head and neck cancer (HNC) patients. This study aims to investigate its incidence and risk factors in this population. MATERIALS AND METHODS: A retrospective review of all HNC patients that had received radiotherapy or chemo radiotherapy with radical intent at a single institution was undertaken (n=206). Dose delivered to the pharyngeal constrictors, base of tongue and cricopharyngeus was calculated and compared between those patients who had died from aspiration pneumonia and those who are alive or had died from other causes...
January 2017: Oral Oncology
https://www.readbyqxmd.com/read/28024718/patterns-of-dysphagia-and-acute-toxicities-in-patients-with-head-and-neck-cancer-undergoing-helical-imrt%C3%A2-concurrent-chemotherapy
#20
Laura B Moroney, Jennifer Helios, Elizabeth C Ward, Jane Crombie, Leesa F Wockner, Clare L Burns, Ann-Louise Spurgin, Claire Blake, Lizbeth Kenny, Brett G M Hughes
BACKGROUND: There is limited prospective data reporting the extent of treatment related toxicities associated with helical Intensity Modulated Radiotherapy (H-IMRT) for head and neck cancer (HNC). The study aim was to investigate severity, peak incidence and recovery patterns of dysphagia and related toxicities in patients undergoing H-IMRT±chemotherapy to examine when patients are experiencing symptoms requiring supportive clinical care. METHODS: Prospective study of 212 patients undergoing H-IMRT...
January 2017: Oral Oncology
keyword
keyword
86260
1
2
Fetch more papers »
Fetching more papers... Fetching...
Read by QxMD. Sign in or create an account to discover new knowledge that matter to you.
Remove bar
Read by QxMD icon Read
×

Search Tips

Use Boolean operators: AND/OR

diabetic AND foot
diabetes OR diabetic

Exclude a word using the 'minus' sign

Virchow -triad

Use Parentheses

water AND (cup OR glass)

Add an asterisk (*) at end of a word to include word stems

Neuro* will search for Neurology, Neuroscientist, Neurological, and so on

Use quotes to search for an exact phrase

"primary prevention of cancer"
(heart or cardiac or cardio*) AND arrest -"American Heart Association"