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pregnancy and retinal detachment

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https://www.readbyqxmd.com/read/29321361/a-novel-contiguous-deletion-involving-ndp-maob-and-efhc2-gene-in-a-patient-with-familial-norrie-disease-bilateral-blindness-and-leucocoria-without-other-deficits
#1
Bei Jia, Liping Huang, Yaoyu Chen, Siping Liu, Cuihua Chen, Ke Xiong, Lanlin Song, Yulai Zhou, Xinping Yang, Mei Zhong
Contiguous microdeletions of the Norrie disease pseudoglioma (NDP) region on chromosome Xp11.3 have been widely confirmed as contributing to the typical clinical features of Norrie disease (ND). However, the precise relation between genotype and phenotype could vary. The contiguous deletion of NDP and its neighbouring genes, MAOA/B and EFHC2, reportedly leads to syndromic clinical features such as microcephaly, intellectual disability, and epilepsy. Herewe report a novel contiguous microdeletion of the NDP region containing the MAOB and EFHC2 genes,which causes eye defects but no cognitive disability...
December 2017: Journal of Genetics
https://www.readbyqxmd.com/read/29205980/retinopathy-of-prematurity-from-recognition-of-risk-factors-to-treatment-recommendations
#2
Reija Fagerholm, Eija Vesti
Retinopathy of prematurity is a proliferative retinal disorder diagnosed exclusively in prematurely born infants. In retinopathy of prematurity, growth of the retinal vasculature is disturbed, leading to hypoxia-induced pathological changes typical of retinopathy of prematurity, in the worst case resulting in retinal detachment. The most typical risk factors predisposing to the disease include hyperoxemia, low levels of insulin-like growth factor 1 (IGF-I), and low birth weight in relation to weeks of pregnancy...
2017: Duodecim; Lääketieteellinen Aikakauskirja
https://www.readbyqxmd.com/read/28894975/reperfusion-of-the-choriocapillaris-observed-using-optical-coherence-tomography-angiography-in-hypertensive-choroidopathy
#3
Miwa Saito, Akihiro Ishibazawa, Reiko Kinouchi, Akitoshi Yoshida
PURPOSE: Optical coherence tomography angiography (OCTA) can visualize the vascular status of the choriocapillaris noninvasively and separately from the other vascular beds. We describe focal ischemia in the choriocapillaris and reperfusion of the area in hypertensive choroidopathy using en-face OCTA. CASE: A 32-year-old woman diagnosed with pregnancy-induced hypertension presented with acute anorthopia in the right eye after delivery via Caesarian section. Fundus examination showed an Elschnig's spot and serous retinal detachment (SRD) in the inferior perifoveal region...
September 11, 2017: International Ophthalmology
https://www.readbyqxmd.com/read/28867885/serious-visual-ocular-complications-in-pre-eclampsia-and-eclampsia
#4
Thangappah Radha Bai Prabhu
INTRODUCTION: Complete loss of vision is an uncommon ocular complication of pre-eclampsia/eclampsia. The conditions which lead to visual loss in pre-eclampsia include cortical blindness, retinal detachment, retinal vascular thrombosis and optic nerve atrophy. OBJECTIVES: The objective was to describe the cause, clinical course and prognosis in blindness complicating pre-eclampsia. METHODOLOGY: This is a prospective observational study conducted at the Govt...
October 2017: Journal of Obstetrics and Gynaecology of India
https://www.readbyqxmd.com/read/28752697/clinical-features-of-pregnancy-associated-retinal-and-choroidal-diseases-causing-acute-visual-disturbance
#5
Young Joo Park, Kyu Hyung Park, Se Joon Woo
PURPOSE: To report clinical features of patients with retinal and choroidal diseases presenting with acute visual disturbance during pregnancy. METHODS: In this retrospective case series, patients who developed acute visual loss during pregnancy (including puerperium) and visited a tertiary hospital from July 2007 to June 2015, were recruited by searching electronic medical records. Patients were categorized according to the cause of visual loss. Clinical features and required diagnostic modalities were analyzed in the retinal and choroidal disease group...
August 2017: Korean Journal of Ophthalmology: KJO
https://www.readbyqxmd.com/read/28626823/a-survey-of-ophthalmologists-and-gynecologists-regarding-termination-of-pregnancy-and-choice-of-delivery-mode-in-the-presence-of-eye-diseases
#6
Seyed-Farzad Mohammadi, Mojgan Letafat-Nejad, Elham Ashrafi, Hanieh Delshad-Aghdam
PURPOSE: To evaluate and compare the attitudes of ophthalmologists and gynecologists in suggesting appropriate approach to pregnancy in different ocular conditions. METHODS: Specialty-specific questionnaires on delivery mode and abortion indications for ophthalmic patients (refractive, vascular, oncologic, retinal, glaucoma, postoperation, posttrauma, and infectious) were designed and distributed among physician staff of Farabi Eye Hospital and Yas Women Hospital in Tehran...
June 2017: Journal of Current Ophthalmology
https://www.readbyqxmd.com/read/28389884/gestational-diabetes-mellitus-is-a-significant-risk-factor-for-long-term-ophthalmic-morbidity
#7
Ofer Beharier, Ruslan Sergienko, Roy Kessous, Irit Szaingurten-Solodkin, Asnat Walfisch, Eden Shusterman, Erez Tsumi, Eyal Sheiner
PURPOSE: To investigate whether patients with a history of gestational diabetes mellitus (GDM) have an increased risk for long-term ophthalmic morbidity. METHODS: Design a population-based study compared the incidence of long-term maternal ophthalmic morbidity in a cohort of women with and without a history of GDM. Setting Soroka University Medical Center. PARTICIPANTS: All singleton pregnancies of women who delivered between 1988 and 2013...
June 2017: Archives of Gynecology and Obstetrics
https://www.readbyqxmd.com/read/28033228/sub-tenon-triamcinolone-acetonide-injection-in-a-pregnant-patient-with-vogt-koyanagi-harada-disease
#8
Tomoko Nakamura, Hiroshi Keino, Annabelle A Okada
PURPOSE: To report a case of new-onset Vogt-Koyanagi-Harada disease treated with sub-Tenon injection of triamcinolone acetonide in a 16-week pregnant patient. METHODS: Review of clinical records. RESULTS: A 33-year-old woman in her 16th week of pregnancy presented with bilateral serous retinal detachments associated with anterior chamber inflammation. Enhanced depth imaging optical coherence topography showed marked choroidal thickening. Headache and tinnitus developed 3 days later...
December 28, 2016: Retinal Cases & Brief Reports
https://www.readbyqxmd.com/read/28002851/prenatal-ultrasonographic-diagnosis-of-cataract-in-utero-manifestations-of-cryptic-disease
#9
Eran Ashwal, Asaf Achiron, Yinon Gilboa, Michal Berkenstadt, Mordecai Rosner, Reuven Achiron
Purpose To report and review our experience with antenatal evaluation for fetuses diagnosed with congenital cataract. Materials and Methods We retrospectively identified pregnancies diagnosed with fetal cataract during antenatal ultrasound. Evaluation of fetal eyes included intraocular anatomy and biometry. Data on fetal malformations, serology and fetal karyotype were collected. Results 8 cases, identified over the course of 10 years, were reviewed. Week 15 was the mean time for diagnosis (range 11 - 34)...
December 21, 2016: Ultraschall in der Medizin
https://www.readbyqxmd.com/read/27926640/preeclampsia-and-long-term-risk-of-maternal-retinal-disorders
#10
Nathalie Auger, William D Fraser, Gilles Paradis, Jessica Healy-Profitós, Ada Hsieh, Marc-André Rhéaume
OBJECTIVE: To evaluate whether preeclampsia is associated with risk of maternal retinal disease in the decades after pregnancy. METHODS: We carried out a longitudinal cohort study of 1,108,541 women who delivered neonates in any hospital in Quebec, Canada, between 1989 and 2013. We tracked women for later hospitalizations until March 31, 2014. Preeclampsia was measured at delivery categorized by severity (mild or severe) and onset (before or at 34 weeks or more of gestation)...
January 2017: Obstetrics and Gynecology
https://www.readbyqxmd.com/read/27800247/bilateral-vision-loss-after-delivery-in-two-cases-severe-preeclampsia-and-hellp-syndrome
#11
Gökhan Çelik, Ahmet Eser, Murat Günay, Nursal Melda Yenerel
Two patients with no symptoms of hypertension in their medical history before pregnancy were referred to the obstetrics emergency clinic with hypertension and visual complaints. After physical examination and laboratory tests, one of the patients was diagnosed with severe preeclampsia while the other was diagnosed with HELLP syndrome (Hemolysis-Elevated Liver enzymes-Low Platelets). Ocular examinations were performed after delivery due to the patients' worsening visual complaints. The severe preeclamptic patient showed bilateral serous retinal detachment (SRD) while the patient with HELLP syndrome showed bilateral macular hemorrhage...
December 2015: Turkish Journal of Ophthalmology
https://www.readbyqxmd.com/read/27778454/quantification-of-fluid-resorption-from-diabetic-macular-oedema-with-foveal-serous-detachment-after-dexamethasone-intravitreal-implant-ozurdex-%C3%A2-in-a-pregnant-diabetic
#12
Delila Hodzic-Hadzibegovic, Shakoor Ba-Ali, Marianne Valerius, Henrik Lund-Andersen
PURPOSE: To quantify the fluid resorption from the centre of the fovea in a pregnant woman with diabetic macular oedema by daily optical coherence tomography (OCT) measurements after the administration of intravitreal dexamethasone implant (Ozurdex(®) ). METHODS: A 36-year-old pregnant woman with type 1 diabetes for 33 years presented with diabetic macular oedema with foveal serous detachment and symptomatic vision loss at 16 gestational weeks. Best-corrected visual acuity (BCVA) in Snellen notation and central retinal volume assessed by optical coherence tomography (OCT, Topcon Corporation) were measured almost on a daily basis the first five weeks after implantation and then 2-3 times per month until childbirth...
May 2017: Acta Ophthalmologica
https://www.readbyqxmd.com/read/27306132/-cesarean-section-and-eye-disorders
#13
Izabella Karska-Basta, Marta Tarasiewicz, Agnieszka Kubicka-Trząska, Joanna Miniewicz, Bożena Romanowska-Dixon
Recently, a growing tendency for cesarean birth has been noted both, in Poland and worldwide. Non-obstetric problems constitute a large part of indications for cesarean section. Many ophthalmologists and obstetricians still believe that high myopia, the presence of peripheral retinal degenerations, history of retinal detachment surgery, diabetic retinopathy, or glaucoma are indications for surgical termination of pregnancy. However, these recommendations are not evidence-based. The literature offers no proof that high myopia and previous retinal surgery increase the risk of retinal detachment during spontaneous vaginal delivery...
2016: Ginekologia Polska
https://www.readbyqxmd.com/read/27057392/considerations-in-management-of-rhegmatogenous-retinal-detachment-in-one-eyed-pregnant-females-a-report-of-two-cases
#14
M Ashish, S Alok, J Elesh, T Shubhi
The aim of this case report is to discuss issues related to management of one eyed pregnant female. A 26-year-old female (Patient A) and 28-year-old female (Patient B) both in second trimester and one eyed presented to our outpatient department with diminution of vision due to rhegmatogenous retinal detachment (RRD). Retina was attached in Patient A following scleral buckling surgery but Patient B required pars plana vitrectomy with silicon oil tamponade. Best corrected visual acuity in both patients did improve from 1/60 to 6/24 and 6/18, respectively at 6 months follow-up...
November 2015: Annals of Medical and Health Sciences Research
https://www.readbyqxmd.com/read/26871904/preeclampsia-and-future-risk-for-maternal-ophthalmic-complications
#15
Ofer Beharier, Ehud Davidson, Ruslan Sergienko, Irit Szaingurten-Solodkin, Roy Kessous, Ron Charach, Nadav J Belfair, Eyal Sheiner
Objective To investigate whether patients with a history of preeclampsia have an increased risk of long-term ophthalmic complications. Study Design A population-based study comparing the incidence of long-term maternal ophthalmic complications in a cohort of women with and without a history of preeclampsia. Results During the study period, a total of 103,183 deliveries met the inclusion criteria; 8.1% (n = 8,324) occurred in patients with a diagnosis of preeclampsia during at least one of their pregnancies...
June 2016: American Journal of Perinatology
https://www.readbyqxmd.com/read/26807496/spontaneous-regression-of-serous-retinal-detachment-associated-with-circumscribed-choroidal-hemangioma-after-childbirth
#16
Isil Sayman Muslubas, Serra Arf, Mumin Hocaoglu, Hakan Ozdemir, Murat Karacorlu
PURPOSE: To report a case of circumscribed choroidal hemangioma complicated by retinal detachment and regressed spontaneously after childbirth. METHODS: Clinical examination, fundus photography, spectral domain optical coherence tomography with enhanced depth imaging, fundus autofluorescence, fluorescein angiography, indocyanine green angiography, and microperimetry. RESULTS: A 41-year-old woman was referred with a 2-week history of decreased vision and scotoma in the left eye...
January 2017: Retinal Cases & Brief Reports
https://www.readbyqxmd.com/read/26697760/fertility-treatments-and-the-risk-for-ophthalmic-complications-a-cohort-study-with-25-year-follow-up
#17
Roy Ratson, Eyal Sheiner, Ehud Davidson, Ruslan Sergienko, Ofer Beharier, Roy Kessous
OBJECTIVE: To investigate whether there is an association between a history of fertility treatments and future risk for long-term maternal ophthalmic complications. STUDY DESIGN: A population-based study compared the incidence of long-term maternal ophthalmic complications in a cohort of women with and without a prior history of fertility treatments, including in vitro fertilization (IVF) and ovulation induction (OI). Deliveries occurred between the years 1988-2013, with a mean follow-up duration of 12 years...
October 2016: Journal of Maternal-fetal & Neonatal Medicine
https://www.readbyqxmd.com/read/26635487/choroidal-thickening-and-macular-serous-retinal-detachment-in-pregnancy-induced-hypertension
#18
Ranko Aoyagi, Takaaki Hayashi, Hiroshi Tsuneoka
OBJECTIVE: The purpose of this study was to report optical coherence tomography (OCT) and angiographic findings in a patient with pregnancy-induced hypertension (PIH). CASE REPORT: A 39-year-old woman, who was diagnosed with PIH, reported blurred and distorted vision at 5 days after an emergency cesarean delivery. OCT revealed a large serous retinal detachment (SRD) that included areas in the macula, along with an increased choroidal thickness noted in both eyes...
2015: International Medical Case Reports Journal
https://www.readbyqxmd.com/read/26595148/choroidal-morphology-in-a-patient-with-hellp-syndrome
#19
Ayaka Kasai, Yukinori Sugano, Ichiro Maruko, Tetsuju Sekiryu
PURPOSE: We report here, the morphological characteristics of the retina and choroid in a patient with hemolysis, elevated liver enzymes, low platelets (HELLP) syndrome, who was not aware of her pregnancy before visiting our hospital. METHODS: Case report. RESULTS: The patient complained of visual disturbances in both eyes for a few days. Extensive serous retinal detachment and hyperreflective foci were observed in both eyes on spectral domain optical coherence tomography (SDOCT)...
2016: Retinal Cases & Brief Reports
https://www.readbyqxmd.com/read/26554764/application-of-optical-coherence-tomography-and-contrast-sensitivity-test-for-observing-fundus-changes-of-patients-with-pregnancy-induced-hypertension-syndrome
#20
Zhixue Wang, Yuanyuan Zou, Wenying Li, Xueyan Wang, Min Zhang, Wenying Wang
This study was aimed to investigate the fundus changes of patients with pregnancy-induced hypertension syndrome (PIHS) using optical coherence tomography (OCT) technology and contrast sensitivity (CS) tests.Ninety-eight patients with PIHS underwent routine eye examinations including vision correction, fundus examination, OCT, and CS tests. The CS test was performed at low, medium, and high frequency, respectively. Moreover, the difference in CS tests between 2 groups was analyzed by independent-samples T test...
November 2015: Medicine (Baltimore)
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