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https://www.readbyqxmd.com/read/29779231/specialist-perioperative-allergy-clinic-services-in-the-uk-2018-results-from-the-royal-college-of-anaesthetists-sixth-national-audit-project-nap6-investigation-of-perioperative-anaphylaxis
#1
W Egner, T M Cook, T Garcez, S Marinho, H Kemp, D N Lucas, K Floss, S Farooque, H Torevell, M Thomas, K Ferguson, S Nasser, S Karanam, K-L Kong, N McGuire, M Bellamy, A Warner, J Hitchman, L Farmer, N J N Harper
BACKGROUND: The Royal College of Anaesthetists 6th National Audit Project examined Grade 3-5 perioperative anaphylaxis for one year in the UK. OBJECTIVE: To describe the causes and investigation of anaphylaxis in the NAP6 cohort, in relation to published guidance and previous baseline survey results. METHODS: We used a secure registry to gather details of Grade 3-5 perioperative anaphylaxis. Anonymous reports were aggregated for analysis and reviewed in detail...
May 19, 2018: Clinical and Experimental Allergy: Journal of the British Society for Allergy and Clinical Immunology
https://www.readbyqxmd.com/read/29777400/ontogeny-of-anastomosed-laticifers-in-the-stem-apex-of-hancornia-speciosa-apocynaceae-a-topographic-approach
#2
Mayara Pereira Gonçalves, Maria Olívia Mercadante-Simões, Leonardo Monteiro Ribeiro
Latex is a complex plant secretion with both ecological and economic importance. There is little information currently available on the cytological aspects of the ontogenesis of anastomosed laticifers, the ducts originating through the lysis of adjacent cell walls. Hancornia speciosa is a tree typical of the Cerrado (neotropical savanna) biome. Its latex has medicinal value and is also used to produce rubber. The ontogenesis of its laticifers and the process of latex synthesis are described here. Structural, cytochemical, and ultrastructural analyses of the stem apex and phytochemical analyses of the latex were performed...
May 18, 2018: Protoplasma
https://www.readbyqxmd.com/read/29773339/quantitation-of-isoprenoids-for-natural-rubber-biosynthesis-in-natural-rubber-latex-by-liquid-chromatography-with-tandem-mass-spectrometry
#3
Xi Zhang, Tianyang Guo, Tong Xiang, Yiyang Dong, Jichuan Zhang, Liqun Zhang
The natural rubber molecule is one of the end products of isoprenoids metabolism in the plant. Dimethylallyl diphosphate (DMAPP) and farnesyl pyrophosphate (FPP) are two typical isoprenoids which control the rate of biosynthesis and the molecular weight of natural rubber. A rapid, nonradioactive method for quantitation of DMAPP and FPP in natural rubber latex by liquid chromatography tandem with mass spectrometry (LC-MS/MS) was reported. DMAPP and FPP were determined in the multiple reaction monitoring mode(MRM)followed by separation with a silica-based C18 column...
May 3, 2018: Journal of Chromatography. A
https://www.readbyqxmd.com/read/29770500/variable-anatomic-configuration-of-the-posterior-spinal-arteries-in-humans
#4
Santiago Rojas, Marisa Ortega, Alfonso Rodríguez-Baeza
INTRODUCTION: Posterior spinal arteries (PSAs) arise from the vertebral (VA) or posterior inferior cerebellar (PICA) artery. We identified variations in their origins and their anastomosis with the first posterior radiculomedullary branches in human spinal cords. MATERIALS AND METHODS: Spinal cords from male and female cadavers (n = 30) were injected with colored latex through the vertebral, ascending cervical, costocervical trunk and segmental arteries. Specimens were fixed in formalin and the spinal arteries were dissected under a surgical microscope...
May 17, 2018: Clinical Anatomy
https://www.readbyqxmd.com/read/29770458/surfactant-effects-on-wettability-of-penicillium-frequentans-formulations-to-improve-brown-rot-biocontrol
#5
Belén Guijarro, Inmaculada Larena, Paloma Melgarejo, Antonieta De Cal
BACKGROUND: Penicillium frequentans could be approach to integrated pest management of brown rot, caused by Monilinia spp. Competition is primary mode of biocontrol activity of P. frequentans, and therefore, it must cover the entire fruit where the pathogen is acting. Our objective was to optimize P. frequentans efficacy, by maximizing fruit surface coverage and retention with the antagonist formulation by surfactant incorporation. RESULTS: Sixteen surfactants were assessed at 3-5 different concentrations and performance of disease-management of brown rot...
May 16, 2018: Journal of the Science of Food and Agriculture
https://www.readbyqxmd.com/read/29768458/burden-of-bacterial-meningitis-in-india-preliminary-data-from-a-hospital-based-sentinel-surveillance-network
#6
Yuvaraj Jayaraman, Balaji Veeraraghavan, Girish Kumar Chethrapilly Purushothaman, Bharathy Sukumar, Boopathi Kangusamy, Ambujam Nair Kapoor, Nivedita Gupta, Sanjay Madhav Mehendale
BACKGROUND: Worldwide, acute bacterial meningitis is a major cause of high morbidity and mortality among under five children, particularly in settings where vaccination for H. influenzae type b, S. pneumoniae and N. meningitidis is yet to be introduced in the national immunization programs. Estimation of disease burden of bacterial meningitis associated with these pathogens can guide the policy makers to consider inclusion of these newer vaccines in the immunization programs. A network of hospital based sentinel surveillance was established to generate baseline data on the burden of bacterial meningitis among children aged less than 5 years in India and to provide a platform for impact assessment following introduction of the Pentavalent and Pneumococcal Conjugate Vaccines (PCV)...
2018: PloS One
https://www.readbyqxmd.com/read/29767525/distribution-of-nanodiamond-inside-the-nanomatrix-in-natural-rubber
#7
Asangi Gannoruwa, Seiichi Kawahara
The distribution of nanodiamond inside a nanomatrix, which is related to the mechanical and viscoelastic properties, is investigated for a natural rubber-nanodiamond composite. The composite is prepared by reacting nanodiamond with deproteinized natural rubber (NR-ND) in the presence of a tert-butylhydroperoxide (TBHPO) / tetraethylenepentamine (TEPA) radical initiator at 30 °C in the latex stage and subsequent drying. The morphology of the composite is observed by 3D transmission electron microscopy (TEM)...
May 16, 2018: Langmuir: the ACS Journal of Surfaces and Colloids
https://www.readbyqxmd.com/read/29765255/distribution-of-pomalidomide-into-semen-of-healthy-male-subjects-after-multiple-doses
#8
Yan Li, Xiaomin Wang, Liangang Liu, Josephine Reyes, Maria Palmisano, Simon Zhou
Objective: To assess whether pomalidomide can distribute into human semen and its duration in human semen. Method: A phase 1, randomized, double-blind, placebo-controlled study (CC-4047-CP-006) was conducted to evaluate the safety, tolerability, and pharmacokinetics of pomalidomide (CC-4047) following multiple daily doses in healthy male subjects. Semen samples were collected on Day -1 and 4 hours after dosing on Day 4 to quantify the pomalidomide concentrations in ejaculate after multiple oral doses of pomalidomide...
2018: Clinical Pharmacology: Advances and Applications
https://www.readbyqxmd.com/read/29764416/safety-of-a-condom-uterine-balloon-tamponade-esm-ubt-device-for-uncontrolled-primary-postpartum-hemorrhage-among-facilities-in-kenya-and-sierra-leone
#9
Aparna Ramanathan, Melody J Eckardt, Brett D Nelson, Moytrayee Guha, Monica Oguttu, Zaid Altawil, Thomas Burke
BACKGROUND: Postpartum hemorrhage is the leading cause of maternal mortality in low- and middle-income countries. While evidence on uterine balloon tamponade efficacy for severe hemorrhage is encouraging, little is known about safety of this intervention. The objective of this study was to evaluate the safety of an ultra-low-cost uterine balloon tamponade package (named ESM-UBT) for facility-based management of uncontrolled postpartum hemorrhage (PPH) in Kenya and Sierra Leone. METHODS: Data were collected on complications/adverse events in all women who had an ESM-UBT device placed among 92 facilities in Sierra Leone and Kenya, between September 2012 and December 2015, as part of a multi-country study...
May 15, 2018: BMC Pregnancy and Childbirth
https://www.readbyqxmd.com/read/29762654/testing-of-disposable-protective-garments-against-isocyanate-permeation-from-spray-polyurethane-foam-insulation
#10
Michael P Mellette, Dhimiter Bello, Yalong Xue, Michael Yost, Anila Bello, Susan Woskie
Background: Diisocyanates (isocyanates), including methylene diphenyl diisocyanate (MDI), are the primary reactive components of spray polyurethane foam (SPF) insulation. They are potent immune sensitizers and a leading cause of occupational asthma. Skin exposure to isocyanates may lead to both irritant and allergic contact dermatitis and possibly contribute to systemic sensitization. More than sufficient evidence exists to justify the use of protective garments to minimize skin contact with aerosolized and raw isocyanate containing materials during SPF applications...
May 12, 2018: Annals of Work Exposures and Health
https://www.readbyqxmd.com/read/29760613/latex-immunotherapy-evidence-of-effectiveness
#11
Eleonora Nucera, Simona Mezzacappa, Alessandro Buonomo, Michele Centrone, Angela Rizzi, Paolo Francesco Manicone, Giampiero Patriarca, Arianna Aruanno, Domenico Schiavino
Introduction: The only etiological and decisive therapy, able to influence the natural history of latex allergy is the specific desensitization. Aim: To verify the clinical efficacy and immunological changes determined by latex sublingual immunotherapy in allergic patients who underwent this treatment for at least 3 years. Material and methods: We enrolled 76 patients (16 males and 60 females, mean age 34 years old) with evidence of a natural rubber latex allergy...
April 2018: Postȩpy Dermatologii i Alergologii
https://www.readbyqxmd.com/read/29752877/characterization-of-rpe-melanin-and-degraded-synthetic-melanin-using-mass-spectrometry-and-in-vitro-biochemical-diagnostics
#12
Sally M Yacout, Kelsey L McIlwain, Shama P Mirza, Elizabeth R Gaillard
With increasing age, there is an observable loss of melanin in retinal pigment epithelial (RPE) cells. It is possible that degradation of the pigment contributes to the pathogenesis of retinal disease, as the cellular antioxidant material is depleted. Functionally, intact melanin maintains protective qualities, while oxidative degradation of melanin promotes reactive oxygen species (ROS) generation and formation of metabolic byproducts, such as melanolipofuscin. Understanding the structural and functional changes to RPE melanin with increasing age may contribute to a better understanding of disease progression and risk factors for conditions such as Age-related macular degeneration (AMD)...
May 12, 2018: Photochemistry and Photobiology
https://www.readbyqxmd.com/read/29750275/endoscopic-endonasal-transclival-approach-to-the-ventral-brainstem-anatomic-study-of-the-safe-entry-zones-combining-fiber-dissection-technique-with-7-tesla-magnetic-resonance-guided-neuronavigation
#13
Alessandro Weiss, Paolo Perrini, Matteo De Notaris, Guadalupe Soria, Alarcon Carlos, Maura Castagna, Lodovico Lutzemberger, Orazio Santo Santonocito, Giuseppe Catapano, Amin Kassam, Alberto Prats Galino
BACKGROUND: Treatment of intrinsic lesions of the ventral brainstem is a surgical challenge that requires complex skull base antero- and posterolateral approaches. More recently, endoscopic endonasal transclival approach (EETA) has been reported in the treatment of selected ventral brainstem lesions. OBJECTIVE: In this study we explored the endoscopic ventral brainstem anatomy with the aim to describe the degree of exposure of the ventral safe entry zones. In addition, we used a newly developed method combining traditional white matter dissection with high-resolution 7T magnetic resonance imaging (MRI) of the same specimen coregistered using a neuronavigation system...
May 10, 2018: Operative Neurosurgery (Hagerstown, Md.)
https://www.readbyqxmd.com/read/29749963/formation-of-spherical-shaped-gan-and-inn-quantum-dots-on-curved-sin-si-surface
#14
Ilgyu Choi, Hyunjoong Lee, Cheul-Ro Lee, Kwang-Un Jeong, Jin Soo Kim
This paper reports the formation of GaN and InN quantum dots (QDs) with symmetric spherical shapes, grown on SiN/Si(111). Spherical QDs are grown by modulating initial growth behavior via gallium and indium droplets functioning as nucleation sites for QDs. Field-emission scanning electron microscope (FE-SEM) images show that GaN and InN QDs are formed on curved SiN/Si(111) instead of on a flat surface similar to balls on a latex mattress. This is considerably different from the structural properties of In(Ga)As QDs grown on GaAs or InP...
May 11, 2018: Nanotechnology
https://www.readbyqxmd.com/read/29748470/effect-of-massoia-massoia-aromatica-becc-bark-on-the-phagocytic-activity-of-wistar-rat-macrophages
#15
Triana Hertiani, Agustinus Yuswanto, Sylvia Utami Tunjung Pratiwi, Harlyanti Muthma'innah Mashar
The essential oil of Massoia ( Massoia aromatica Becc., Lauraceae) bark is a potential immunomodulator in vitro. This study evaluated the potential immunomodulatory effects of Massoia bark infusion on the nonspecific immune response (phagocytosis) of Wistar rats. For the in vitro assay, macrophages were treated with the freeze-dried infusion at the concentrations of 2.5, 5, 10, 20, or 40 µg/mL media. For the in vivo assay, two-month-old male Wistar rats were divided into five groups. The baseline group received distilled water at the dose of 1 mL/100 g body weight (BW), with the herbal product containing Phyllanthus niruri extract that was administered as the positive control at the dose of 0...
May 10, 2018: Scientia Pharmaceutica
https://www.readbyqxmd.com/read/29746633/in-vitro-study-of-force-decay-of-latex-and-non-latex-orthodontic-elastics
#16
Noelia López, Ascensión Vicente, Luis A Bravo, José L Calvo Guirado, Manuel Canteras
No abstract text is available yet for this article.
May 9, 2018: European Journal of Orthodontics
https://www.readbyqxmd.com/read/29743585/evaluating-the-temperature-effects-of-ice-and-heat-tests-on-ptosis-due-to-myasthenia-gravis
#17
Emmanuel Marinos, Katherine Buzzard, Clare L Fraser, Stephen Reddel
AIMS: The aims of this study are as follows: (1) to describe a standardised methodology for the ice test, and where necessary a heat test; (2) to determine the effects of local cooling vs. heating on ptosis in myasthenia gravis (MG) patients. METHODS: Twenty-three MG patients with ptosis were identified from a tertiary referral neuroimmunology clinic, seventeen with significant ptosis ≥2 mm. Latex party balloons were filled with ice and cold tap water for the ice test, or with water heated to 45 °C for the heat test...
May 10, 2018: Eye
https://www.readbyqxmd.com/read/29740228/use-of-wood-vinegar-to-enhance-5-aminolevulinic-acid-production-by-selected-rhodopseudomonas-palustris-in-rubber-sheet-wastewater-for-agricultural-use
#18
Tomorn Nunkaew, Duangporn Kantachote, Sumate Chaiprapat, Teruhiko Nitoda, Hiroshi Kanzaki
This study aimed to produce inexpensive 5-aminolevulinic acid (ALA) in a non-sterile latex rubber sheet wastewater (RSW) by Rhodopseudomonas palustris TN114 and PP803 for the possibility to use in agricultural purposes by investigating the optimum conditions, and applying of wood vinegar (WV) as an economical source of levulinic acid to enhance ALA content. The Box-Behnken Design experiment was conducted under microaerobic-light conditions for 96 h with TN114, PP803 and their mixed culture (1:1) by varying initial pH, inoculum size (% v/v) and initial chemical oxygen demand (COD, mg/L)...
May 2018: Saudi Journal of Biological Sciences
https://www.readbyqxmd.com/read/29738405/effect-of-exercise-on-cognition-conditioning-muscle-endurance-and-balance-in-older-adults-with-mild-cognitive-impairment-a-randomized-controlled-trial
#19
Chandra da Silveira Langoni, Thais de Lima Resende, Andressa Bombardi Barcellos, Betina Cecchele, Mateus Soares Knob, Tatiane do Nascimento Silva, Juliana Nunes da Rosa, Tamiris de Souza Diogo, Irenio Gomes da Silva Filho, Carla Helena Augustin Schwanke
BACKGROUND AND PURPOSE: Mild cognitive impairment (MCI) may be a precursor to dementia; however, its progression may be prevented or slowed with exercise. This study aimed at determining the effects of group aerobic and strength training on cognition, conditioning, muscle endurance, and balance in underprivileged community-dwelling older adults with MCI. METHODS: This was a single-blind, randomized, and matched-pair controlled (gender, age, body mass index, and Addenbrooke's Cognitive Examination-Revised for MCI diagnosis) clinical trial...
May 4, 2018: Journal of Geriatric Physical Therapy
https://www.readbyqxmd.com/read/29731476/prevalence-of-toxoplasma-gondii-and-other-intestinal-parasites-in-cats-in-tokachi-sub-prefecture-japan
#20
Doaa Salman, Wilawan Pumidonming, Eiji Oohashi, Makoto Igarashi
The present study investigated the prevalence of Toxoplasma gondii and other intestinal parasites in cats in the Tokachi subprefecture in Japan. A total of 365 household cats were included in the study, and 353 serum and 351 fecal samples were collected and analyzed. T. gondii IgG antibodies were detected in the sera of 16.14% of cats based on Latex agglutination test and ELISA. For ELISA, T. gondii RH strain tachyzoites lysate and T. gondii SAG2 recombinant protein were used as antigens. Low seropositivity was detected in cats younger than one year and older than 11 years; outdoor and hunter cats showed significantly high seropositivities...
May 2, 2018: Journal of Veterinary Medical Science
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