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https://www.readbyqxmd.com/read/27873521/a-case-of-recurrent-urticaria-due-to-formaldehyde-release-from-root-canal-disinfectant
#1
Ji Hoon Jang, Seung Hyun Park, Hang Jea Jang, Sung Geun Lee, Jin Han Park, Jae Won Jeong, Chan Sun Park
Although formaldehyde is well known to cause type 4 hypersensitivity, immunoglobulin E (IgE)-mediated hypersensitivity to formaldehyde is rare. Here, we report a case of recurrent generalized urticaria after endodontic treatment using a para-formaldehyde (PFA)-containing root canal sealant and present a review of previous studies describing cases of immediate hypersensitivity reactions to formaldehyde. A 50-year-old man visited our allergy clinic for recurrent generalized urticaria several hours after endodontic treatment...
January 2017: Yonsei Medical Journal
https://www.readbyqxmd.com/read/27785085/treatment-challenges-in-the-management-of-moderate-to-severe-plaque-psoriasis-role-of-secukinumab
#2
REVIEW
Mona Malakouti, Sharon E Jacob, Nancy J Anderson
Psoriasis is a chronic inflammatory skin disease that has a negative impact on psychosocial well-being and cardiometabolic health. Treatment options for moderate-to-severe psoriasis have expanded with the development of interleukin-17 (IL-17) inhibitors, the first of which is now available - secukinumab. Secukinumab is a fully human monoclonal immunoglobulin G1 κ antibody that selectively inhibits the ligand IL-17A. In head-to-head studies, it is more effective than etanercept and ustekinumab, particularly in achieving Psoriasis Area and Severity Index (PASI) 90/100 and achieving PASI 50/75 as early as week 4...
2016: Clinical, Cosmetic and Investigational Dermatology
https://www.readbyqxmd.com/read/27732749/is-kiwifruit-allergy-a-matter-in-kiwifruit-cultivating-regions-a-population-based-study
#3
Mehtap Haktanir Abul, Selim Dereci, Sadan Hacisalihoglu, Fazil Orhan
BACKGROUND: Although kiwifruit is known as a common cause of food allergy, population-based studies concerning the prevalence of kiwifruit allergy do not exist. We aimed to determine the prevalence and clinical characteristics of IgE-mediated kiwifruit allergy in 6-18-year-old urban schoolchildren in a region where kiwifruit is widely cultivated. METHODS: This cross-sectional study recruited 20,800 of the randomly selected 6-18-year-old urban schoolchildren from the Rize city in the eastern Black Sea region of Turkey during 2013...
October 12, 2016: Pediatric Allergy and Immunology
https://www.readbyqxmd.com/read/27590896/cannabis-sativa-allergy-looking-through-the-fog
#4
Ine I Decuyper, Athina L Van Gasse, Nathalie Cop, Vito Sabato, Margaretha Faber, Christel Mertens, Chris H Bridts, Margo M Hagendorens, Luc De Clerck, H P Rihs, Didier G Ebo
IgE-mediated Cannabis (C. sativa, marihuana) allergy seems to be on the rise. Both active and passive exposure to cannabis allergens may trigger a C. sativa sensitization and/or allergy. The clinical presentation of a C. sativa allergy varies from mild to life-threatening reactions and often seems to depend on the route of exposure. In addition, sensitization to cannabis allergens can result in various cross-allergies, mostly for plant foods. This clinical entity, designated as the "cannabis-fruit/vegetable syndrome" might also imply cross-reactivity with tobacco, natural latex and plant-food derived alcoholic beverages...
September 3, 2016: Allergy
https://www.readbyqxmd.com/read/27585420/benzodiazepine-allergy-with-anesthesia-administration-a-review-of-current-literature
#5
Elliot Haybarger, Andrew S Young, Joseph A Giovannitti
The incidence of anaphylactic/anaphylactoid reactions has been reported to vary between 1 : 3500 and 1 : 20,000 cases with a mortality rate ranging from 3 to 9%. Clinical signs present as skin rash, urticaria, angioedema, bronchospasm, tachycardia, bradycardia, and hypotension. Rapid identification and treatment are crucial to overall patient prognosis, as delayed intervention is associated with increased mortality. Diagnosis may be confirmed with clinical presentation, serum tryptase levels, and skin test results...
2016: Anesthesia Progress
https://www.readbyqxmd.com/read/27580724/-mucosal-diseases-from-an-allergological-perspective
#6
I Schwarz, D Bokanovic, W Aberer
The oral allergy syndrome is one of the most common form of food allergy and manifests as contact urticaria of the oral mucosa after consumption of cross reacting foods. Whereas allergic contact stomatitis often occurs due to dental materials, allergic contact cheilitis is usually a reaction due to topical therapeutics like herpes ointments or lip care products. As late type reactions are more frequent than immediate type reactions in the anogenital mucosa, contact dermatitis in this area should be identified via epicutaneous testing...
October 2016: Der Hautarzt; Zeitschrift Für Dermatologie, Venerologie, und Verwandte Gebiete
https://www.readbyqxmd.com/read/27469013/content-of-asthmagen-natural-rubber-latex-allergens-in-commercial-disposable-gloves
#7
C Bittner, Marcial Velasco Garrido, L H Krach, V Harth
The use of natural rubber latex (NRL) gloves in many occupations may lead to latex sensitization, allergic asthma, and skin reactions. Due to their good properties and environmental safety NRL gloves are still being used in the healthcare setting, but also in the food industry, by hairdressers, cleaners, etc. The aim of our study was to assess the protein and NRL allergen content in commercial gloves by different methods, including a new assay. Twenty commercially available NRL gloves were analyzed. Protein extraction was performed according to the international standard ASTM D-5712...
July 29, 2016: Advances in Experimental Medicine and Biology
https://www.readbyqxmd.com/read/27436328/occupational-skin-disease-among-australian-healthcare-workers-a-retrospective-analysis-from-an-occupational-dermatology-clinic-1993-2014
#8
Claire L Higgins, Amanda M Palmer, Jennifer L Cahill, Rosemary L Nixon
BACKGROUND: Healthcare workers (HCWs) are at risk of developing occupational skin disease (OSD). OBJECTIVES: To ascertain the causes of OSD in Australian HCWs in a tertiary referral clinic. METHODS: A retrospective review was performed of patients assessed at the Occupational Dermatology Clinic in Melbourne from 1993 to 2014. RESULTS: Of 685 HCWs assessed in the clinic over a period of 22 years, 555 (81.0%) were diagnosed with OSD...
October 2016: Contact Dermatitis
https://www.readbyqxmd.com/read/27388267/influence-of-material-properties-on-gloves-bacterial-barrier-efficacy-in-the-presence-of-microperforation
#9
Michael Hermann Bardorf, Bernd Jäger, Eric Boeckmans, Axel Kramer, Ojan Assadian
BACKGROUND: Medical examination gloves and surgical gloves protect the wearer directly and the patient indirectly from the risk of contamination. Because of concerns related to latex allergy, an increasing trend toward the use of synthetic gloves made of materials other than latex is observable. However, currently it is unknown if the physical properties of different materials may influence bacterial passage in case of a glove puncture. METHODS: We examined 9 different medical examination gloves from various manufacturers made of nitrile (n = 4), latex (n = 3), or neoprene (n = 2)...
December 1, 2016: American Journal of Infection Control
https://www.readbyqxmd.com/read/27354157/-latex-allergy-in-a-paediatric-hospital-characteristics-and-risk-factors
#10
Michael Bailey, Ximena Norambuena, Gigia Roizen, Jorge Rodríguez, Arnoldo Quezada
INTRODUCTION: The prevalence of latex sensitisation varies according to the population studied. There are various risk factors that increase latex sensitisation, such as genetic risk, atopy, and multiple surgeries. OBJECTIVE: To characterise patients referred to an Immunology Unit with suspected latex allergy, and to analyse their clinical features and risk factors. PATIENTS AND METHOD: A retrospective, descriptive study was conducted on children suspected of latex allergy...
June 25, 2016: Revista Chilena de Pediatría
https://www.readbyqxmd.com/read/27352907/prevalence-of-delayed-type-and-immediate-type-hypersensitivity-in-healthcare-workers-with-hand-eczema
#11
Kristina S Ibler, Gregor B E Jemec, Lene H Garvey, Tove Agner
BACKGROUND: Occupational contact dermatitis is common in healthcare workers. Although irritant contact dermatitis resulting from wet work is the most frequently reported cause, healthcare workers also constitute high-risk group for the development of allergic contact dermatitis and contact urticaria. OBJECTIVES: To evaluate the prevalence of delayed-type and immediate-type hypersensitivity in 120 healthcare workers with hand eczema. METHODS: One hundred and twenty healthcare workers from three major hospitals in Denmark with self-reported hand eczema within the last year participated in the study...
October 2016: Contact Dermatitis
https://www.readbyqxmd.com/read/27279821/differentiating-of-cross-reactions-in-patients-with-latex-allergy-with-the-use-of-isac-test
#12
Marta Chełmińska, Krzysztof Specjalski, Anna Różyło, Agata Kołakowska, Ewa Jassem
INTRODUCTION: Differentiating between cross-reactivity and double sensitization is still a challenging issue in allergology. AIM: To differentiate cross-reactions accompanying latex allergy with the use of the ISAC test. MATERIAL AND METHODS: Thirty-nine patients reporting immediate allergic reactions to latex were enrolled into the study (group A). The control group was comprised of 41 patients with allergic diseases not associated with latex (group B) and 20 healthy individuals (group C)...
April 2016: Postȩpy Dermatologii i Alergologii
https://www.readbyqxmd.com/read/27241513/content-of-asthmagen-natural-rubber-latex-allergens-in-commercial-disposable-gloves
#13
C Bittner, M V Garrido, L H Krach, V Harth
The use of natural rubber latex (NRL) gloves in many occupations may lead to latex sensitization, allergic asthma, and skin reactions. Due to their good properties and environmental safety NRL gloves are still being used in the healthcare setting, but also in the food industry, by hairdressers, cleaners, etc. The aim of our study was to assess the protein and NRL allergen content in commercial gloves by different methods, including a new assay. Twenty commercially available NRL gloves were analyzed. Protein extraction was performed according to the international standard ASTM D-5712...
2016: Advances in Experimental Medicine and Biology
https://www.readbyqxmd.com/read/27181074/epidemiology-of-perioperative-anaphylaxis
#14
Paul Michel Mertes, Gerald W Volcheck, Lene H Garvey, Tonomori Takazawa, Peter R Platt, Anne B Guttormsen, Charles Tacquard
Anaphylactic reactions may be either of immune (allergy, usually IgE-mediated, sometimes IgG-mediated) or non-immune origin. The incidence of anaphylactic reactions during anaesthesia varies between countries ranging from 1/1250 to 1/18,600 per procedure. In France, the estimated incidence of allergic reactions is 100.6 [76.2-125.3]/million procedure with a high female predominance (male: 55.4 [42.0-69.0], female: 154.9 [117.2-193.1]). The proportion of IgE-mediated allergic reactions seems to be relatively similar between countries, ranging from 50 to 60%...
September 2016: La Presse Médicale
https://www.readbyqxmd.com/read/27179970/a-case-of%C3%A2-severe%C3%A2-nsaid-exacerbated-respiratory-disease-nerd-following-a-dental-procedure-in-a-child
#15
G King, A Byrne, P Fleming
BACKGROUND: An allergic reaction following a dental procedure is a rare event. A local anaesthetic (LA) may initially be suspected as a causative agent but allergy to dental LA solutions is extremely rare. CASE REPORT: This report concerns a 13 year old child who underwent dental treatment and was exposed to Lignospan Special(®) LA, mouthwash, latex gloves, ibuprofen medication, and a Magnum(®) (almond) ice cream all within 45 min. He subsequently developed acute symptoms of nasal rhinorrhoea, facial flushing, peri-orbital and lip angioedema, followed by throat tightness and wheeze (respiratory compromise)...
August 2016: European Archives of Paediatric Dentistry: Official Journal of the European Academy of Paediatric Dentistry
https://www.readbyqxmd.com/read/27174758/-latex-sensitization-prevalence-through-prick-test-in-patients-with-genitourinary-malformations-and-more-than-3-surgeries
#16
Ana Paola Macías-Robles, Ana Rocío Morán-Mendoza
BACKGROUND: Latex allergy is a public health issue. It presents elevated prevalence in known risk groups, especially in those patients with spine bifida condition, urinal malformation and for those with orthopedic problems - multiple surgeries. Health Services in Mexico do not have the enough studies about prevalence and risk associated to latex allergy. OBJECTIVE: Determine latex sensitization prevalence through PRICK test in patients with genitourinary malformations and more than 3 surgeries in UMAE pediatric CMNO unit, considering too related factors...
April 2016: Revista Alergia Mexico: Organo Oficial de la Sociedad Mexicana de Alergia e Inmunología, A.C
https://www.readbyqxmd.com/read/27152604/a-regional-approach-to-unmet-needs-in-anaphylaxis
#17
P Minale, D Bignardi, C Troise, S Voltolini, P Dignetti
Allergic diseases are under-diagnosed and undertreated despite their wide prevalence, and particularly anaphylaxis is often under-estimated. Evidence-based anaphylaxis guidelines developed by principal allergy organizations agree on increased prevalence of anaphylaxis, especially in patients younger than 18 years (18-27,30): this trend highlights the need for actions on anaphylaxis management and prevention (3,4). Lack of prompt connection between emergency department and allergy unit after discharge, and of a dedicated ICD-9th identification code (18-26), can delay diagnosis and treatment of anaphylaxis (28,29)...
May 2016: European Annals of Allergy and Clinical Immunology
https://www.readbyqxmd.com/read/27103909/occupational-health-related-concerns-among-surgeons
#18
REVIEW
Anjuman Gul Memon, Zahid Naeem, Atif Zaman, Faryal Zahid
The surgeon's daily workload renders him/her susceptible to a variety of the common work-related illness. They are exposed to a number of occupational hazards in their professional work. These hazards include sharp injuries, blood borne pathogens, latex allergy, laser plumes, hazardous chemicals, anesthetic gases, equipment hazards, static postures, and job related stressors. However, many pay little attention to their health, and neither do they seek the appropriate help when necessary. It is observed that occupational hazards pose a huge risk to the personal well-being of surgeons...
April 2016: International Journal of Health Sciences
https://www.readbyqxmd.com/read/27102974/occupational-allergic-contact-dermatitis-in-a-2-year-follow-up-study-how-well-does-the-patient-remember-the-result-of-patch-testing
#19
Line Brok, Kim K B Clemmensen, Tanja K Carøe, Niels E Ebbehøj, Tove Agner
BACKGROUND: Patch testing is mandatory for diagnosing contact dermatitis. It is, however, crucial that patients understand and remember the result of the test. OBJECTIVES: The aim of our study was to evaluate the impact of patch testing with respect to patients' ability to remember patch test results and the results of natural rubber latex protein allergy after 2 years. METHODS: One hundred and ninety-nine patients diagnosed with relevant occupational epoxy or rubber chemical contact allergy, or allergy to natural rubber latex protein, were invited to participate in a questionnaire study about their knowledge of contact allergies after 2 years...
April 21, 2016: Contact Dermatitis
https://www.readbyqxmd.com/read/27090058/treating-ige-mediated-diseases-via-targeting-ige-expressing-b-cells-using-an-anti-c%C3%AE%C2%B5mx-antibody
#20
REVIEW
Sean S Liour, Andrew Tom, Yueh-Hsuan Chan, Tse Wen Chang
Targeting the IgE pathway is a clinically validated strategy for treating IgE-mediated diseases. Omalizumab, an anti-IgE antibody, which binds to free IgE and prevents the binding of IgE to FcεRI on mast cells and basophils has been approved for severe persistent allergic asthma and chronic spontaneous (idiopathic) urticaria. The therapeutic efficacy of anti-IgE has also been reported in allergic rhinitis, allergic bronchopulmonary aspergillosis, latex allergy, atopic dermatitis, allergic urticaria, anaphylaxis, and others...
August 2016: Pediatric Allergy and Immunology
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