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Hormonal contraception side effectS

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https://www.readbyqxmd.com/read/29732216/can-the-evolution-of-male-contraception-lead-to-a-revolution-review-of-the-current-state-of-knowledge
#1
Mikołaj Frankiewicz, Wojciech Połom, Marcin Matuszewski
Introduction: Great advances in medical research concerning methods of contraception have been achieved in recent years, however, more than 25% of couples worldwide still rely on condoms - a method with poor efficacy. Even though there is a spectrum of 11 different contraceptive methods for women, there are only 4 commonly used by men (condoms, periodic abstinence, withdrawal and vasectomy). In this review, advances and present, state-of-the-art, both hormonal and non-hormonal male contraceptive methods will be presented and evaluated...
2018: Central European Journal of Urology
https://www.readbyqxmd.com/read/29685519/contraception-in-dogs-and-cats
#2
REVIEW
Cheryl S Asa
Although surgical sterilization is the most common approach to reproductive management of dogs and cats in North America and many other places, there is growing interest in nonsurgical and reversible methods. This review summarizes the methods currently available for use as reversible contraception in dogs and cats, along with cautions about reported side effects. The products covered include synthetic steroid hormones, peptide hormone agonists, vaccines, and a barrier method.
April 20, 2018: Veterinary Clinics of North America. Small Animal Practice
https://www.readbyqxmd.com/read/29610676/pregnant-or-recently-pregnant-opioid-users-contraception-decisions-perceptions-and-preferences
#3
Rebecca L Fischbein, Bethany G Lanese, Lynn Falletta, Kelsey Hamilton, Jennifer A King, Deric R Kenne
Background: Multiple factors are linked to extremely high unintended pregnancy rates among women who use opioids, including various barriers to contraception adherence. These include patient level barriers such as lack of knowledge and education about highly effective contraception, and potential provider barriers. Using a mixed-methods framework to examine the contraception-related perceptions and preferences of opioid using women is a necessary next step to understanding this phenomenon...
2018: Contraception and reproductive medicine
https://www.readbyqxmd.com/read/29566064/hormonal-contraception-increases-the-risk-of-psychotropic-drug-use-in-adolescent-girls-but-not-in-adults-a-pharmacoepidemiological-study-on-800-000-swedish-women
#4
Sofia Zettermark, Raquel Perez Vicente, Juan Merlo
The burden of depression and anxiety disorders is greater in women, and female sex hormones have been shown to affect mood. Psychological side effects of hormonal contraception (HC) are also a common complaint in the clinic, but few previous studies have investigated this subject. We therefore wanted to investigate whether use of HC was associated with adverse psychological health outcomes, and whether this association was modified by age. All women aged 12-30 years on 31 December 2010, residing in Sweden for at least four years and with no previous psychiatric morbidity (n = 815 662), were included...
2018: PloS One
https://www.readbyqxmd.com/read/29553474/preventing-pregnancy-in-kenya-through-distribution-and-use-of-the-cyclebeads-mobile-application
#5
Victoria Shelus, Nicki Ashcroft, Sarah Burgess, Monica Giuffrida, Victoria Jennings
CONTEXT: Given the proportion of Kenyan women not using hormonal contraceptives, the country appears to have a substantial need for a modern, natural family planning option. The CycleBeads® mobile phone application (app), a digital platform for the Standard Days Method® of family planning, could help address this issue. METHODS: After the CycleBeads app was promoted in Kenya in May-June 2015, a three-month pilot study was conducted to collect quantitative and qualitative data from 185 female app users...
September 1, 2017: International Perspectives on Sexual and Reproductive Health
https://www.readbyqxmd.com/read/29530557/-endometriosis-medical-treatment-hormonal-treatment-for-the-management-of-pain-and-endometriotic-lesions-recurrence-cngof-has-endometriosis-guidelines
#6
S Geoffron, J Cohen, M Sauvan, G Legendre, J M Wattier, E Daraï, H Fernandez, N Chabbert-Buffet
The available literature, from 2006 to 2017, on hormonal treatment has been analysed as a contribution to the HAS-CNGOF task force for the treatment of endometriosis. Available data are heterogeneous and the general level of evidence is moderate. Hormonal treatment is usually offered as the primary option to women suffering from endometriosis. It cannot be used in women willing to conceive. In women who have not been operated, the first line of hormonal treatment includes combined oral contraceptives (COC) and the levonorgestrel-releasing intra uterine system (52mg LNG-IUS)...
March 2018: Gynecologie, Obstetrique, Fertilite & Senologie
https://www.readbyqxmd.com/read/29517451/assessing-the-efficacy-of-deslorelin-acetate-implants-suprelorin-in-alternative-placement-sites
#7
Veronica B Cowl, Susan L Walker, Yedra Feltrer Rambaud
Hormonal contraception is being increasingly used to manage captive animals in zoological collections. Many of the animals placed on contraception are of genetic importance within captive breeding programs; therefore, it is imperative that the application of contraceptive products minimize potential side effects and facilitate a return to fertility if required. Deslorelin acetate implants (Suprelorin®) are one example of a hormonal contraceptive that is frequently used in captivity as they are easy to use and effective in most species...
March 2018: Journal of Zoo and Wildlife Medicine: Official Publication of the American Association of Zoo Veterinarians
https://www.readbyqxmd.com/read/29496473/etonogestrel-implant-use-in-women-primarily-choosing-a-combined-oral-contraceptive-pill-a-proof-of-concept-trial
#8
Melissa J Chen, Jennifer K Hsia, Mitchell D Creinin
OBJECTIVE: We evaluated a novel concept of initiating the etonogestrel implant as a "back-up" method in women who desire using combined oral contraceptives (COC) but want to decrease their risk of unintended pregnancy with a more effective method. STUDY DESIGN: In this prospective cohort study, we planned to include 20 women as a proof-of-concept. We enrolled both new COC starters and continuing COC users and placed an etonogestrel implant. Participants completed daily bleeding diaries and attended follow-up visits at 1, 3, and 6 months...
February 26, 2018: Contraception
https://www.readbyqxmd.com/read/29483855/the-role-of-levonorgestrel-intrauterine-systems-in-the-treatment-of-symptomatic-fibroids
#9
REVIEW
Wojciech Wrona, Anna Stępniak, Piotr Czuczwar
Uterine fibroids are considered to be the most frequently occurring tumours in females. The majority of fibroids do not require any treatment. When symptomatic, the major ailments include abnormal uterine bleeding, painful menstruation, pelvic pressure or pain, urinary problems, constipation, infertility, and recurrent pregnancy loss. Surgery remains a mainstay of symptomatic uterine fibroids therapy; however, minimally-invasive techniques and pharmacological management have become more available. The levonorgestrel intrauterine system (LNG-IUS) is a T-shaped device with a vertical stem containing a reservoir of levonorgestrel and is widely known for its contraception effect...
December 2017: Przeglad Menopauzalny, Menopause Review
https://www.readbyqxmd.com/read/29445408/needs-and-preferences-of-women-users-of-oral-contraceptives-in-selected-countries-in-central-and-eastern-europe
#10
Tomas Fait, Dmitry Buryak, Monica-Mihaela Cirstoiu, Eva Luczai, Rafal Janczura
Background: The availability of various oral contraceptive (OC) pill formulations with different hormone compositions suggests that there is potential to align a particular product with an individual user's needs and preferences. To explore this concept further, a survey was conducted of current users of OCs to define and confirm areas of specific needs, and to gain insight into their views and preferences for OC formulations. Methods: During November and December 2015, women users (n=615) of OCs in five Central and Eastern European countries were surveyed in face-to-face interviews conducted by experienced interviewers...
2018: Drugs in Context
https://www.readbyqxmd.com/read/29430227/levonorgestrel-releasing-intrauterine-device-related-acute-liver-injury
#11
Hira Imad Cheema, Ashutosh Gupta
Oral contraceptives have long been associated with liver injury. However, very little attention is paid to the metabolic side effects of hormone-releasing intrauterine devices (IUDs). These devices are generally considered safe and commonly used. We report for the first time acute liver injury associated with a levonorgestrel-releasing IUD. Our patient did not have any comorbidities that could have caused or exacerbated liver injury. A detailed workup and liver biopsy remained negative for any other potential cause of liver injury...
September 2017: Case Reports in Gastroenterology
https://www.readbyqxmd.com/read/29359527/treatment-of-premenstrual-mood-changes-in-a-patient-with-schizophrenia-using-dienogest-a-case-report
#12
Yasuhiko Kamada, Ai Sakamoto, Sayoko Kotani, Hisashi Masuyama
Dienogest is a fourth-generation progestin that is used for the treatment of endometriosis. We report a case of premenstrual mood changes in a patient with schizophrenia who was unresponsive to conventional treatment but successfully managed with dienogest. A 37-year-old Japanese woman with schizophrenia was referred to our hospital and diagnosed with premenstrual exacerbation of schizophrenia or coexisting premenstrual dysphoric disorder with schizophrenia. She had already taken maximal doses of selective serotonin reuptake inhibitors and combined oral contraceptives produced intolerable side effects...
April 2018: Journal of Obstetrics and Gynaecology Research
https://www.readbyqxmd.com/read/29355224/rationale-and-design-of-a-multi-center-open-label-randomised-clinical-trial-comparing-hiv-incidence-and-contraceptive-benefits-in-women-using-three-commonly-used-contraceptive-methods-the-echo-study
#13
G Justus Hofmeyr, Charles S Morrison, Jared M Baeten, Tsungai Chipato, Deborah Donnell, Peter Gichangi, Nelly Mugo, Kavita Nanda, Helen Rees, Petrus Steyn, Douglas Taylor
BACKGROUND: In vitro, animal, biological and observational clinical studies suggest that some hormonal methods, particularly depot medroxyprogesterone acetate - DMPA, may increase women's risk of HIV acquisition. DMPA is the most common contraceptive used in many countries worst affected by the HIV epidemic. To provide robust evidence for contraceptive decision-making among women, clinicians and planners, we are conducting the Evidence for Contraceptive Options and HIV Outcomes (ECHO) study in four countries with high HIV incidence and DMPA use: Kenya, South Africa, Swaziland, and Zambia (Clinical Trials...
December 29, 2017: Gates open research
https://www.readbyqxmd.com/read/29347814/-customization-of-hormonal-contraception
#14
Vincenzo DE Leo, Antonio Cianci, Costantino DI Carlo, Valentina Cappelli, Franca Fruzzetti
In the last few years new oral contraceptives have been marketed showing a better safety profile for women. They are the result of important changes made to the old compounds. As far as the estrogenic component, with the aim of decreasing side effects, the dose of ethinyl estradiol has been reduced and synthetic estrogens have been replaced by natural estradiol, further improving the safety profile. Also the progestin component in the last years has been changed in terms of dose, endocrine and metabolic characteristics...
February 2018: Minerva Ginecologica
https://www.readbyqxmd.com/read/29283683/period-prevalence-and-perceived-side-effects-of-hormonal-contraceptive-use-and-the-menstrual-cycle-in-elite-athletes
#15
Daniel Martin, Craig Sale, Simon B Cooper, Kirsty J Elliott-Sale
PURPOSE: To identify the period prevalence of hormonal contraceptive (HC) use and characterise the perceived side effects associated with the menstrual cycle and HC use. METHODS: 430 elite female athletes completed a questionnaire to assess; the period prevalence of HC use, the reasons for initiation and discontinuation of HCs and the side effects experienced by HC and non-HC users. Descriptive statistics, between-group comparisons and associations between categorical variables were calculated...
December 28, 2017: International Journal of Sports Physiology and Performance
https://www.readbyqxmd.com/read/29201429/side-effects-and-the-need-for-secrecy-characterising-discontinuation-of-modern-contraception-and-its-causes-in-ethiopia-using-mixed-methods
#16
Alexandra Alvergne, Rose Stevens, Eshetu Gurmu
Background: Contraceptive discontinuation is a major barrier to reducing global unmet needs for family planning, but the reasons why women discontinue contraception are poorly understood. Here we use data from Ethiopia to investigate (i) the magnitude of contraceptive discontinuation in 2005-2011, (ii) how the risk of discontinuation varies with method type and education level and (iii) the barriers to continuation. Our main hypothesis is that contraceptive discontinuation is driven by the experience of physiological side-effects associated with the use of hormonal contraception, rather than a lack of formal education...
2017: Contraception and Reproductive Medicine
https://www.readbyqxmd.com/read/29092828/how-i-treat-heavy-menstrual-bleeding-associated-with-anticoagulants
#17
Kochawan Boonyawat, Sarah H O'Brien, Shannon M Bates
Anticoagulant-associated heavy menstrual bleeding (HMB) is an underrecognized but not uncommon problem in clinical practice. Premenopausal women should be advised of the potential effect of anticoagulant therapy on menstrual bleeding at the time of treatment initiation. Consequences of HMB should be assessed and treated on an ongoing basis. In the acute setting, the decision to withhold anticoagulants is based on an individual patient's risk of thrombosis and the severity of the bleeding. For women who require long-term anticoagulation, a levonorgestrel intrauterine system, tranexamic acid (during menstrual flow), high-dose progestin-only therapy, or combined hormonal contraceptives are effective for controlling HMB...
December 14, 2017: Blood
https://www.readbyqxmd.com/read/29041977/perceptions-of-and-barriers-to-family-planning-services-in-the-poorest-regions-of-chiapas-mexico-a-qualitative-study-of-men-women-and-adolescents
#18
Emily Dansereau, Alexandra Schaefer, Bernardo Hernández, Jennifer Nelson, Erin Palmisano, Diego Ríos-Zertuche, Alex Woldeab, Maria Paola Zúñiga, Emma Margarita Iriarte, Ali H Mokdad, Charbel El Bcheraoui
BACKGROUND: In the poorest regions of Chiapas, Mexico, 50.2% of women in need of contraceptives do not use any modern method. A qualitative study was needed to design effective and culturally appropriate interventions. METHODS: We used purposive maximum-variation sampling to select eight municipalities with a high proportion of residents in the poorest wealth quintile, including urban, rural, indigenous, and non-indigenous communities. We conducted 44 focus group discussions with 292 women, adolescent women, and men using semi-structured topic guides...
October 17, 2017: Reproductive Health
https://www.readbyqxmd.com/read/28994639/migraine-menopause-and-hormone-replacement-therapy
#19
E Anne MacGregor
Perimenopause marks a period of increased migraine prevalence in women and many women also report troublesome vasomotor symptoms. Migraine is affected by fluctuating estrogen levels with evidence to support estrogen 'withdrawal' as a trigger of menstrual attacks of migraine without aura, while high estrogen levels can trigger migraine aura. Maintaining a stable estrogen environment with estrogen replacement can benefit estrogen-withdrawal migraine particularly in women who would also benefit from relief of vasomotor symptoms...
March 2018: Post Reproductive Health
https://www.readbyqxmd.com/read/28966755/premenstrual-syndrome-symptomatic-and-diagnosed-prevalence-dualistic-treatment-approach-a-cross-sectional-study-in-ukraine
#20
Edith Meszaros Crow, Emilien Jeannot
BACKGROUND: Diagnosing and treatment of premenstrual syndrome (PMS) still pose a challenge in the routine medical practice which usually focuses on single pharmacological therapy. Recent research suggests that the combination of treatments including complementary alternative medicine (CAM) therapies may be more beneficial. The objective of this study was to assess the percentage of diagnosed and nondiagnosed PMS/premenstrual dysphoric disorder (PMDD) based on the presence of adequate symptoms and to compare population using hormonal or pharmaceutical agents versus CAM therapies...
2017: International Journal of Preventive Medicine
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