keyword
https://read.qxmd.com/read/38479218/adverse-events-associated-with-device-assisted-hyoid-and-tongue-base-suspension-for-obstructive-sleep-apnea
#21
JOURNAL ARTICLE
Jane Y Tong, Wiktoria A Gocal, Sunny J Haft
PURPOSE: Hyoid and tongue base suspension may treat obstructive sleep apnea (OSA). This study summarizes device-related adverse events associated with the AIRvance and AIRLIFT systems used for hyoid and tongue base suspension. MATERIALS AND METHODS: The U.S. Food and Drug Administration's Manufacturer and User Facility Device Experience (MAUDE) database was queried for reports describing adverse events associated with hyoid or tongue base suspension from January 2012 to December 2022...
February 27, 2024: American Journal of Otolaryngology
https://read.qxmd.com/read/38472700/pulmonary-hypertension-in-newly-diagnosed-obstructive-sleep-apnea-chronic-obstructive-pulmonary-disease-overlap-syndrome-patients-attending-a-tertiary-care-centre-a-cross-sectional-analysis
#22
JOURNAL ARTICLE
Jyothi Reshma S, Sunny George, Santhosh Kumar P
INTRODUCTION: Overlap syndrome is the association of obstructive sleep apnea (OSA) with chronic obstructive pulmonary disorder and with other chronic respiratory diseases. Patients with overlap syndrome have a worse prognosis compared with chronic obstructive pulmonary disorder or OSA alone. Additionally, patients with combined chronic obstructive pulmonary disorder and OSA are more likely to develop pulmonary hypertension and right heart failure much earlier than those without overlap...
March 12, 2024: Irish Journal of Medical Science
https://read.qxmd.com/read/38471433/personality-traits-and-pre-treatment-beliefs-and-cognitions-predicting-patient-adherence-to-continuous-positive-airway-pressure-a-systematic-review
#23
REVIEW
P Kasetti, N F Husain, T C Skinner, K Asimakopoulou, J Steier, S A Sathyapala
Adherence to Continuous Positive Airway Pressure (CPAP) for obstructive sleep apnoea (OSA) can be improved by behavioural interventions which modify patients' beliefs and cognitions about OSA, CPAP, and themselves. We have conducted the first systematic review of the literature on beliefs and cognitions held before starting treatment, and personality (which influences the former) that predict the decision to purchase or start CPAP, or CPAP adherence one month or more after CPAP initiation. A systematic search and screen of articles identified 21 eligible publications from an initial 1317...
February 21, 2024: Sleep Medicine Reviews
https://read.qxmd.com/read/38468601/item-response-theory-analysis-of-daytime-sleepiness-as-a-symptom-of-obstructive-sleep-apnea
#24
JOURNAL ARTICLE
Gustaf J Wellhagen, Mats O Karlsson, Maria C Kjellsson, Dirk Garmann, Astrid Bröker, Yang Zhang, Mika Nokela, Gerrit Weimann, Ashraf Yassen
Obstructive sleep apnea (OSA) is a sleep disorder which is linked to many health risks. The gold standard to evaluate OSA in clinical trials is the Apnea-Hypopnea Index (AHI). However, it is time-consuming, costly, and disregards aspects such as quality of life. Therefore, it is of interest to use patient-reported outcomes like the Epworth Sleepiness Scale (ESS), which measures daytime sleepiness, as surrogate end points. We investigate the link between AHI and ESS, via item response theory (IRT) modeling. Through the developed IRT model it was identified that AHI and ESS are not correlated to any high degree and probably not measuring the same sleepiness construct...
March 12, 2024: CPT: Pharmacometrics & Systems Pharmacology
https://read.qxmd.com/read/38461515/patients-perceptions-of-the-importance-of-improvements-and-side-effects-from-mandibular-advancement-device-therapy-for-obstructive-sleep-apnea-and-snoring
#25
JOURNAL ARTICLE
Luca Mezzofranco, Francesca Zalunardo, Sorina Savin, Ludovica Agostini, Antonio Luigi Tiberio Gracco
OBJECTIVE: To assess which improvements and side effects are considered most important by patients with OSA treated with a MAD. METHODS: A specific questionnaire consisting of 20 questions, including 10 questions on improvements and 10 on side effects, was developed and mailed to all subjects (54). RESULTS: 42 patients, participated in the survey by answering the questionnaire. The results showed that patients placed greater importance on the positive outcomes of treatment, with the most significant being the reduction in snoring and improvement in sleep quality...
March 10, 2024: Cranio: the Journal of Craniomandibular Practice
https://read.qxmd.com/read/38460649/a-ph-responsive-tannic-acid-quaternized-carboxymethyl-chitosan-oxidized-sodium-alginate-hydrogels-for-accelerated-diabetic-wound-healing-and-real-time-monitoring
#26
JOURNAL ARTICLE
Zhifei Yang, Chen Wang, Zhiyuan Zhang, Fangzheng Yu, Yu Wang, Jianqiang Ding, Zheng Zhao, Yichao Liu
Treatment of diabetic wounds is a major clinical issue. Diabetic wound dressings have higher requirements for anti-oxidant, antibacterial and wound monitoring properties compared to conventional wound dressings. In this study, a novel tannic acid (TA)/quaternized carboxymethyl chitosan (QCMCS)/oxidized sodium alginate (OSA)@carbon quantum dots (CQD) (TA/QCMCS/OSA@CQD) hydrogels for promoting diabetic wound healing and real-time monitoring have been developed. The TA/QCMCS/OSA@CQD hydrogels exhibited excellent self-healing, antibacterial and antioxidant properties...
March 7, 2024: International Journal of Biological Macromolecules
https://read.qxmd.com/read/38460418/pharmacological-interventions-for-pediatric-obstructive-sleep-apnea-osa-network-meta-analysis
#27
REVIEW
Yuxiao Zhang, Siqi Leng, Qian Hu, Yingna Li, Yumeng Wei, You Lu, Di Qie, Fan Yang
IMPORTANCE: Pediatric obstructive sleep apnea (OSA) is a common disease that can have significant negative impacts on a child's health and development. A comprehensive evaluation of different pharmacologic interventions for the treatment of OSA in children is still lacking. OBJECTIVE: This study aims to conduct a comprehensive systematic review and network meta-analysis of pharmacological interventions for the management of obstructive sleep apnea in pediatric population...
February 6, 2024: Sleep Medicine
https://read.qxmd.com/read/38460066/effect-of-continuous-positive-airway-pressure-on-blood-pressure-in-patients-with-resistant-hypertension-and-obstructive-sleep-apnea-an-updated-meta-analysis
#28
REVIEW
Ling Sun, Ya-Fei Chang, Yun-Fei Wang, Quan-Xin Xie, Xian-Zhong Ran, Chun-Yang Hu, Bin Luo, Bin Ning
PURPOSE OF REVIEW: The effect of continuous positive airway pressure (CPAP) on resistant hypertension in patients at high risk with obstructive sleep apnea (OSA) needs further investigation. We aimed to determine the effect of CPAP on blood pressure in patients with resistant hypertension and OSA. Databases including PubMed, EMBASE, MEDLINE, the Cochrane Library, and CMB were searched. Data were pooled using a random-effects or fixed-effects model to derive weighted mean differences (WMDs) and 95% confidence intervals (CIs)...
March 9, 2024: Current Hypertension Reports
https://read.qxmd.com/read/38457003/obstructive-sleep-apnea-the-effect-of-bariatric-surgery-after-five-years-a-prospective-multicenter-trial
#29
JOURNAL ARTICLE
Pipsa Peromaa-Haavisto, Markku Luostarinen, Risto Juusela, Henri Tuomilehto, Jyrki Kössi
BACKGROUND: The prevalence of obstructive sleep apnea (OSA) is high among the bariatric surgery candidates. Obesity is the most important individual risk factor for OSA. The aim of this study was to investigate the effect of a laparoscopic Roux-en-Y gastric bypass (LRYGB) on OSA 5 years after the surgery. PATIENTS AND METHODS: In this prospective multicenter study, standard overnight cardiorespiratory recording was conducted to 150 patients at baseline prior to bariatric surgery...
March 8, 2024: Obesity Surgery
https://read.qxmd.com/read/38451037/defining-the-shape-of-the-mylohyoid-muscle-a-morphometric-imaging-study
#30
JOURNAL ARTICLE
Linda C Magaña, Barton F Branstetter, Ryan J Soose
OBJECTIVES: Implantable hypoglossal nerve stimulation (HNS) therapy is an evolving therapeutic alternative for patients with refractory obstructive sleep apnea (OSA). The muscular anatomy of this region has implications for surgical access through this zone as well as positioning and anchoring of hardware in this area. The purpose of this study was to radiologically describe the topography of the mylohyoid muscle and adjacent structures across a wide age spectrum. METHODS: We retrospectively evaluated computed tomography scans of the neck in 102 patients who were imaged for reasons unrelated to the floor of mouth or submental space...
March 7, 2024: Laryngoscope
https://read.qxmd.com/read/38450516/case-report-of-hypoglossal-nerve-stimulation-therapy-failure-due-to-significant-underlying-central-sleep-apnea
#31
Dhruba Banerjee, Chang-Hoon Lee, Kyoungbin Im
Hypoglossal nerve stimulation (HNS) is indicated for obstructive sleep apnea (OSA) but is ineffective in treating central sleep apnea (CSA). We describe two patients implanted with HNS after being diagnosed with OSA at outside sleep labs and failing a trial of continuous positive airway pressure (CPAP) therapy. Despite successful HNS implantation, the patients continued to have persistent symptoms with residual apnea-hypopnea indices above 25 events/h. Although OSA was the presenting diagnosis, we discovered a significant CSA component in the original diagnostic sleep data upon careful review...
March 7, 2024: Journal of Clinical Sleep Medicine: JCSM: Official Publication of the American Academy of Sleep Medicine
https://read.qxmd.com/read/38449471/a-comprehensive-review-of-solriamfetol-to-treat-excessive-daytime-sleepiness
#32
REVIEW
Mitchell C Fuller, Samuel Carlson, Haley Pysick, Vince Berry, Andrew Tondryk, Hayden Swartz, Elyse M Cornett, Adam M Kaye, Omar Viswanath, Ivan Urits, Alan D Kaye
PURPOSE OF REVIEW: This is a comprehensive review of the literature regarding the use of Solriamfetol for excessive daytime sleepiness. It covers the background and current therapeutic approaches to treating excessive daytime sleepiness, the management of common comorbidities, and the existing evidence investigating the use of Solriamfetol for this purpose. RECENT FINDINGS: Excessive daytime sleepiness leads to worse quality of life, a medical sequela and significant economic cost...
March 4, 2024: Psychopharmacology Bulletin
https://read.qxmd.com/read/38448183/-research-status-of-glucagon-like-peptide-1-receptor-agonists-on-obstructive-sleep-apnea
#33
JOURNAL ARTICLE
B N Zhou, X Liu, K Hu
Obstructive sleep apnea (OSA) is the most common sleep-disordered breathing disease. Continuous positive airway pressure (CPAP) is the gold standard for treatment, but compliance is suboptimal. Therefore, new therapeutic strategies need to be explored. OSA is often associated with multiple comorbidities, particularly type 2 diabetes and obesity. Effective weight loss is known to be crucial in reversing OSA and its associated comorbidities. However, sustained weight loss is difficult to achieve with lifestyle changes alone...
March 12, 2024: Chinese Journal of Tuberculosis and Respiratory Diseases
https://read.qxmd.com/read/38448064/sociological-determinants-of-adherence-to-continuous-positive-airway-pressure-in-the-management-of-sleep-apnoea-syndrome-protocol-for-a-transdisciplinary-prospective-observational-study
#34
JOURNAL ARTICLE
Sebastien Bailly, Alison Foote, Monique Mendelson, Andry Rakotovao, Jean Christian Borel, Jean Louis Pepin, Renaud Tamisier, Helena Revil
INTRODUCTION: Obstructive sleep apnoea syndrome (OSAS) is a chronic multiorgan pathology that has a negative impact on quality of life. Continuous positive airway pressure (CPAP) is the first-line treatment for OSAS. However, CPAP termination rates remain very high, and adherence to therapy is a major issue. To date, studies targeting predictive factors of CPAP adherence by OSAS patients mainly include clinical data. The social, socioeconomic, psychological, and home environment aspects have been far less studied and largely underestimated...
March 5, 2024: BMJ Open
https://read.qxmd.com/read/38447086/sleep-apnea-and-incident-stroke-in-a-national-cohort-of-black-and-white-adults
#35
JOURNAL ARTICLE
Rebecca Robbins, Ya Yuan, Dayna A Johnson, D Leann Long, Jennifer Molano, Dawn Kleindorfer, Megan E Petrov, Virginia J Howard
BACKGROUND AND OBJECTIVES: Racial/ethnic differences have been documented in the relationship between obstructive sleep apnea (OSA) and stroke incidence, yet racial differences in OSA symptoms or treatment and their relationship with stroke incidence are underexplored and may contribute to stroke disparities. We comprehensively examined OSA symptoms and their relationships to stroke incidence by race/ethnicity. METHODS: Data were collected from the REasons for Geographic and Racial Differences in Stroke (REGARDS) study, a population-based cohort of Black and White individuals in the United States...
March 26, 2024: Neurology
https://read.qxmd.com/read/38440629/barbed-suspension-bridge-pharyngoplasty-introducing-a-novel-technique-for-barbed-pharyngoplasty
#36
JOURNAL ARTICLE
Vikas K Agrawal, Rahul R Gupta
Surgical management of Obstructive Sleep Apnea (OSA) and Snoring has undergone many major and minor changes over a period of last decade. The most common surgical approach for OSA is uvulopalatopharyngoplasty (Stuck et al. in Sleep Med 50:152-165, 2018). The main goals of treatment of OSA are to decrease the risk of deleterious health effects and improve quality of sleep (Evans et al. in Otolaryngol Clin North Am 53: 319-328, 2020). Since bimanual surgical techniques in the depth of oral cavity have been tricky, search for a less demanding & easy to learn technique is always on...
February 2024: Indian Journal of Otolaryngology and Head and Neck Surgery
https://read.qxmd.com/read/38440610/an-evaluation-of-obstructive-sleep-apnea-patient-s-quality-of-life-following-continuous-positive-airway-pressure-and-uvulopalatopharyngoplasty
#37
JOURNAL ARTICLE
Arezu Najafi, Moin Ala, Amin Amali, Nafiseh Hivechi, Reihaneh Heidari, Yousef Mokary
AIMS: Obstructive sleep apnea (OSA) is characterized by episodic sleep state-dependent upper airway collapse. OSA can markedly decrease quality of life (QoL) and productivity. Continuous Positive Airway Pressure (CPAP) has been used as an effective treatment for OSA. Recently, uvulopalatopharyngoplasty (UPPP) treatment has emerged as effective management among patients with OSA, especially non-adherent ones to conventional therapies such as CPAP. Our aim was to determine whether CPAP and UPPP treatment could improve the quality of life in patients with moderate OSA...
February 2024: Indian Journal of Otolaryngology and Head and Neck Surgery
https://read.qxmd.com/read/38440565/understanding-correlation-of-polysomnography-parameters-with-drug-induced-sleep-endoscopy-in-obstructive-sleep-apnea
#38
JOURNAL ARTICLE
Sampurna Ghosh, Srinivas Kishore
The aim of this study was to analyze drug-induced sleep endoscopy (DISE) findings performed in 64 patients and to evaluate the association of DISE findings with PSG parameters. This retrospective, single center, observational study included patients with obstructive sleep apnoea (OSA) who have undergone DISE as part of surgical planning. DISE was performed using dexmedetomidine infusion. The data were documented as per VOTE (velum, oropharynx, tongue base and epiglottis) classification. The patient characteristics and level 2 Polysomnography (PSG) findings were analyzed with DISE findings...
February 2024: Indian Journal of Otolaryngology and Head and Neck Surgery
https://read.qxmd.com/read/38440255/prevalence-of-central-sleep-apnea-among-veterans-and-response-rate-to-continuous-positive-airway-pressure-therapy
#39
JOURNAL ARTICLE
Nesrine Adly Ibrahim, Abdulghani Sankari, Ahmad Aldwaikat, Nishtha Pandya, Susmita Chowdhuri, Anan Salloum, Jennifer L Martin, Salam Zeineddine, M Safwan Badr
STUDY OBJECTIVES: Sleep-disordered breathing (SDB) is common in the Veteran population. In this retrospective study, we investigated the prevalence of comorbid central and obstructive SDB and the response rate to PAP among Veterans. METHODS: Veterans were screened from a single VA medical center who had polysomnography (PSG) study from 2017 to 2021 to ascertain the presence, severity, and type of SDB by measuring the apnea-hypopnea index (AHI) and central apnea index (CAI)...
2024: Sleep advances: a journal of the Sleep Research Society
https://read.qxmd.com/read/38440203/a-multifaceted-approach-to-seizure-management-in-a-patient-with-down-syndrome-obstructive-sleep-apnea-and-hypothyroidism-a-case-report
#40
Takafumi Uchi, Shingo Konno, Hideo Kihara, Hideki Sugimoto
In this case study, a 16-year-old male with Down syndrome (DS) faced persistent nocturnal seizures despite anti-seizure medications and treatment for concurrent hypothyroidism. Obstructive sleep apnea (OSA), a common issue in patients with Down syndrome, was revealed as a trigger of the seizures. The implementation of continuous positive airway pressure (CPAP) therapy along with medication adjustments led to a significant decrease in seizure frequency, highlighting the importance of a comprehensive approach to seizure management in patients with complex medical conditions...
March 2024: Curēus
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