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https://www.readbyqxmd.com/read/28429854/application-of-3c-insulin-pump-system-in-combination-with-non-invasive-ventilation-in-the-treatment-of-a-patient-with-type-2-diabetes-and-obstructive-sleep-apnea-syndrome
#1
Peng Dong, Jing Xu, Junhong Wang, Chunhong Zhang
We observed the curative effect of 3C insulin system in combination with non-invasive ventilation in a patient with type 2 diabetes and obstructive sleep apnea syndrome (OSAS). 3C insulin pump is a system of devices that closely monitors and effectively regulates blood glucose levels. Non-invasive ventilation has been shown to be an effective treatment for OSAS. A type 2 diabetic patient with concomitant OSAS was treated with a 3C insulin pump system for real-time continuous glucose monitoring and nocturnal non-invasive ventilation for OSAS...
April 21, 2017: Journal of Diabetes Investigation
https://www.readbyqxmd.com/read/28429850/association-of-obstructive-sleep-apnea-with-arterial-stiffness-and-nondipping-blood-pressure-in-patients-with-hypertension
#2
Raimundo Jenner, Fernanda Fatureto-Borges, Valéria Costa-Hong, Heno F Lopes, Sandra H Teixeira, Elias Marum, Dante A M Giorgi, Fernanda M Consolim-Colombo, Luiz A Bortolotto, Geraldo Lorenzi-Filho, Eduardo M Krieger, Luciano F Drager
Whether sex influences the association of obstructive sleep apnea (OSA) with markers of cardiovascular risk in patients with hypertension is unknown. In this study, 95 hypertensive participants underwent carotid-femoral pulse wave velocity, 24-hour ambulatory blood pressure monitoring, echocardiogram, and polysomnography after a 30-day standardized treatment with hydrochlorothiazide plus enalapril or losartan. OSA was present in 52 patients. Compared with non-OSA patients, pulse wave velocity values were higher in the OSA group (men: 11...
April 21, 2017: Journal of Clinical Hypertension
https://www.readbyqxmd.com/read/28429032/obstructive-sleep-apnoea-and-type-2-diabetes-mellitus-are-they-connected
#3
Yingjuan Mok, Chee Wei Tan, Hang Siang Wong, Choon How How, Kah Leong Alvin Tan, Pon Poh Hsu
Obstructive sleep apnoea (OSA), a sleep-related breathing condition, is diagnosed based on a patient's apnoea-hypopnea index from a sleep study, and the presence or absence of symptoms. Diabetes mellitus (DM) and OSA share a significant common risk factor, obesity, with all three conditions contributing to the risk of developing cardiovascular diseases. The pathophysiological links between OSA and DM are still unclear, but intermittent hypoxia may be an important mechanism. More awareness of the possible link between OSA and DM is needed, given their increasing prevalence locally and worldwide...
April 2017: Singapore Medical Journal
https://www.readbyqxmd.com/read/28423486/tick-host-conflict-immunoglobulin-e-antibodies-to-tick-proteins-in-patients-with-anaphylaxis-to-tick-bite
#4
Lourdes Mateos-Hernández, Margarita Villar, Angel Moral, Carmen García Rodríguez, Teresa Alfaya Arias, Verónica de la Osa, Francisco Feo Brito, Isabel G Fernández de Mera, Pilar Alberdi, Francisco Ruiz-Fons, Alejandro Cabezas-Cruz, Agustín Estrada-Peña, José de la Fuente
Tick-borne infectious diseases and allergies are a growing problem worldwide. Tick bite allergy has been associated with the direct effect of immunoglobulin E (IgE) response to tick salivary antigens, or secondary to the induction of allergy to red meat consumption through IgE antibodies against the carbohydrate α-Gal (Gal α 1-3Gal β 1-(3)4GlcNAc-R). However, despite the growing burden of this pathology, the proteins associated with anaphylaxis to tick bite have not been characterized. To address this question, a comparative proteomics approach was used to characterize tick proteins producing an IgE antibody response in a healthy individual with record of tick bites, which had not resulted in any allergic reactions, and two patients with anaphylactic reactions to Rhipicephalus bursa or Hyalomma marginatum tick bites...
March 28, 2017: Oncotarget
https://www.readbyqxmd.com/read/28422345/therapeutic-efficacy-of-twin-block-and-fixed-oral-appliances-in-patients-with-obstructive-sleep-apnea-syndrome
#5
George Umemoto, Hideo Toyoshima, Yuji Yamaguchi, Naoko Aoyagi, Chikara Yoshimura, Kouta Funakoshi
PURPOSE: To compare the efficacy of twin-block (i.e., allows mouth opening) and fixed (i.e., maintains mouth closure) mandibular advancement splints (MASs) for the treatment of obstructive sleep apnea-hypopnea syndrome (OSA). MATERIALS AND METHODS: From 2011 to 2013, 23 patients with OSA in the twin-block group, and from 2013 to 2015, 29 patients in the fixed MAS group were included. All patients underwent polysomnography before and after 3 months of treatment. The two sets of polysomnographic and cephalometric variables were compared...
April 19, 2017: Journal of Prosthodontics: Official Journal of the American College of Prosthodontists
https://www.readbyqxmd.com/read/28419387/effect-of-continuous-positive-airway-pressure-treatment-on-health-related-quality-of-life-and-sleepiness-in-high-cardiovascular-risk-individuals-with-sleep-apnea-best-apnea-interventions-for-research-bestair-trial
#6
Ying Y Zhao, Rui Wang, Kevin J Gleason, Eldrin F Lewis, Stuart F Quan, Claudia M Toth, Michael Morrical, Michael Rueschman, Jia Weng, James H Ware, Murray A Mittleman, Susan Redline
Study Objectives: The long term effect of continuous positive airway pressure (CPAP) on health-related quality of life (HRQOL) in patients with high cardiovascular disease risk and obstructive sleep apnea (OSA) without severe sleepiness is uncertain. We aimed to determine the effect of CPAP treatment on HRQOL in individuals with moderate or severe OSA and cardiovascular disease (CVD) or multiple CVD risk factors without severe sleepiness. Methods: In this randomized, controlled, parallel group study, 169 participants were assigned to treatment with CPAP or the control group (conservative medical therapy [CMT] or CMT with sham CPAP)...
April 17, 2017: Sleep
https://www.readbyqxmd.com/read/28419320/therapeutic-cpap-level-predicts-upper-airway-collapsibility-in-patients-with-obstructive-sleep-apnea-therapeutic-cpap-predicts-upper-airway-collapsibility
#7
Shane A Landry, Simon A Joosten, Danny J Eckert, Amy S Jordan, Scott A Sands, David P White, Atul Malhotra, Andrew Wellman, Garun S Hamilton, Bradley A Edwards
Study Objectives: Upper airway collapsibility is a key determinant of obstructive sleep apnea (OSA) which can influence the efficacy of certain non-CPAP treatment for OSA. However, there is no simple way to measure this variable clinically. The present study aimed to develop a clinically implementable tool to evaluate the collapsibility of a patient's upper airway. Methods: Collapsibility, as characterized by the passive pharyngeal critical closing pressure (Pcrit), was measured in 46 patients with OSA...
April 13, 2017: Sleep
https://www.readbyqxmd.com/read/28418014/the-relationship-between-allergic-status-and-adenotonsillar-regrowth-a-retrospective-research-on-children-after-adenotonsillectomy
#8
Zirong Huo, Jun Shi, Yilai Shu, Mingliang Xiang, Jingrong Lu, Hao Wu
Adenotonsillar regrowth in children after adenotonsillectomy (T&A) for obstructive sleep apnea (OSA) is often seen in clinical treatment, however, the relationship between allergic disease and adenotonsillar regrowth remains unclear. In this retrospective study, children were assigned to either the recurrence or control group, and subdivided by age at operation. Among children over 36 months, those in the recurrence group had more allergic disease and higher IgE, IL-4, and IL-5 levels than the same-aged children in control group...
April 18, 2017: Scientific Reports
https://www.readbyqxmd.com/read/28417661/corrective-nasal-surgery-after-maxillomandibular-advancement-for-obstructive-sleep-apnea-experience-from-379-cases
#9
Stanley Yung-Chuan Liu, Pi-Jung Lee, Michael Awad, Robert W Riley, Soroush Zaghi
Objective Efficacy of maxillomandibular advancement (MMA) in the treatment of obstructive sleep apnea (OSA) is associated with degree of maxillary advancement. Large maxillary advancement leads to profound changes of the nasolabial region. We present the incidence and indications of post-MMA corrective nasal surgery in a large cohort. Study Design Case series with chart review. Setting University medical center. Subjects and Methods A total of 379 subjects with OSA underwent MMA at Stanford Hospital (surgeons: S...
April 1, 2017: Otolaryngology—Head and Neck Surgery
https://www.readbyqxmd.com/read/28416044/treatment-of-ptsd-related-osa-with-cpap-is-associated-with-only-a-modest-improvement-in-ptsd-possible-adjunctive-treatment-with-mood-stabilizers
#10
Madhulika A Gupta
No abstract text is available yet for this article.
April 12, 2017: Journal of Clinical Sleep Medicine: JCSM: Official Publication of the American Academy of Sleep Medicine
https://www.readbyqxmd.com/read/28409851/response-to-a-combination-of-oxygen-and-a-hypnotic-as-treatment-for-obstructive-sleep-apnoea-is-predicted-by-a-patient-s-therapeutic-cpap-requirement
#11
Shane A Landry, Simon A Joosten, Scott A Sands, David P White, Atul Malhotra, Andrew Wellman, Garun S Hamilton, Bradley A Edwards
BACKGROUND AND OBJECTIVE: Upper airway collapsibility predicts the response to several non-continuous positive airway pressure (CPAP) interventions for obstructive sleep apnoea (OSA). Measures of upper airway collapsibility cannot be easily performed in a clinical context; however, a patient's therapeutic CPAP requirement may serve as a surrogate measure of collapsibility. The present work aimed to compare the predictive use of CPAP level with detailed physiological measures of collapsibility...
April 13, 2017: Respirology: Official Journal of the Asian Pacific Society of Respirology
https://www.readbyqxmd.com/read/28408103/effect-of-cpap-on-diastolic-function-in-coronary-artery-disease-patients-with-nonsleepy-obstructive-sleep-apnea-a-randomized-controlled-trial
#12
Helena Glantz, Magnus C Johansson, Erik Thunström, Cecilia Wallentin Guron, Harun Uzel, Mustafa Saygin, Johan Herlitz, Yüksel Peker
BACKGROUND: Obstructive sleep apnea (OSA) has been associated with worse diastolic function in patients with coronary artery disease (CAD). This analysis determined whether continuous positive airway pressure (CPAP) treatment would improve diastolic function in CAD patients with nonsleepy OSA. METHODS: Between December 2005 and November 2010, 244 revascularized CAD patients with nonsleepy OSA (apnea-hypopnea index (AHI) ≥15/h, Epworth Sleepiness Scale [ESS] score<10) were randomly assigned to CPAP or no-CPAP...
March 25, 2017: International Journal of Cardiology
https://www.readbyqxmd.com/read/28407080/genome-wide-changes-in-microrna-expression-during-short-and-prolonged-heat-stress-and-recovery-in-contrasting-rice-cultivars
#13
Satendra K Mangrauthia, Sailaja Bhogireddy, Surekha Agarwal, Vishnu V Prasanth, S R Voleti, Sarla Neelamraju, Desiraju Subrahmanyam
MicroRNAs (miRNAs) are known to regulate expression of genes under stress. We report here the deep sequencing of small RNAs expressed during control, short and prolonged heat stress and recovery. Genome-wide identification of miRNAs in tolerant (Nagina 22) and susceptible (Vandana) rice cultivars was performed in 16 samples representing root and shoot of 13-day-old seedlings. The expression profile of miRNAs was analysed in 36 pairwise combinations to identify the genotype-, treatment- and tissue-dependent expression of miRNAs...
April 12, 2017: Journal of Experimental Botany
https://www.readbyqxmd.com/read/28406882/impact-of-patient-education-on-compliance-with-positive-airway-pressure-treatment-in-obstructive-sleep-apnea
#14
Sema Saraç, Gülgün Çetintaş Afşar, Özlem Oruç, Özgür Bilgin Topçuoğlu, Cüneyt Saltürk, Yüksel Peker
BACKGROUND We addressed the impact of patient education followed by frequent visits on compliance with positive airway pressure (PAP) treatment in patients with obstructive sleep apnea (OSA) in a Turkish sleep clinic cohort. MATERIAL AND METHODS This single-center, randomized, controlled study was conducted in Istanbul, Turkey between June 2014 and April 2015. Among 115 eligible OSA patients (mean age 51.0±9.3 years; 75.5% men), 63 were randomized to standard support (SS) group (general information about OSA and PAP treatment at baseline), and 52 to educational support (ES) group (additional polysomnography chart viewing from both diagnostic and titration nights)...
April 13, 2017: Medical Science Monitor: International Medical Journal of Experimental and Clinical Research
https://www.readbyqxmd.com/read/28399695/the-effect-of-adenotonsillectomy-on-obstructive-sleep-apnea-in-children-with-down-syndrome
#15
Mosaad Abdel-Aziz, Khaled Azooz, Nader Naguib, Ramez Reda, Ahmed Kamel
OBJECTIVE: Children with Down syndrome (DS) are liable to develop obstructive sleep apnea (OSA) due to many anatomical airway abnormalities. The tonsils and adenoid occupy part of the airway space, and their removal may be helpful in relieving airway obstruction. The aim of this study was to assess the effectiveness of adenotonsillectomy in the treatment of OSA in those children. METHODS: Fifty DS children with difficult breathing were recruited, and they were subjected to polysomnographic examination (PSG)...
April 11, 2017: Acta Oto-laryngologica
https://www.readbyqxmd.com/read/28399379/physiology-of-arousal-in-osa-and-potential-impacts-for-sedative-treatment
#16
Amy S Jordan, Fergal J O'Donoghue, Jennifer M Cori, John Trinder
Treatment options for patients with obstructive sleep apnea (OSA) intolerant of continuous positive airway pressure (CPAP) are limited. Thus, new therapies are sought. Recently, there has been interest in using sedatives to delay arousal from sleep, allowing upper airway dilator muscle recruitment sufficient to re-open the airway while maintaining sleep. In this review the rationale for sedative use and prior sedative studies in OSA are presented, along with a description of six factors that may determine sedative treatment success...
April 11, 2017: American Journal of Respiratory and Critical Care Medicine
https://www.readbyqxmd.com/read/28398157/effects-of-continuous-positive-airway-pressure-on-fatigue-in-two-patients-with-obstructive-sleep-apnea-presenting-with-chronic-fatigue-case-report-and-lessons-learned-from-a-failed-trial
#17
Els Tobback, Liesbeth Delesie, Ignace Hanoulle, Dirk Vogelaers, Dirk Pevernagie, An Mariman
INTRODUCTION: Patients referred to tertiary care for multidisciplinary investigation of unexplained chronic fatigue are not seldom diagnosed with obstructive sleep apnoea (OSA). As standard treatment for OSA, continuous positive airway pressure (CPAP) has been shown to decrease daytime sleepiness in OSA patients. However, the effect on fatigue as major complaint in chronic fatigue patients without excessive daytime sleepiness, is not fully understood nor explored. CASE REPORT: A prospective cross-over trial using effective and sham CPAP treatment periods in patients with unexplained chronic fatigue and OSA was interrupted because of poor recruitment and retainment due to complex design issues...
April 11, 2017: Acta Clinica Belgica
https://www.readbyqxmd.com/read/28397553/preoperative-drug-induced-sleep-endoscopy-improves-the-surgical-approach-to-treatment-of-obstructive-sleep-apnea
#18
Colin Huntley, David Chou, Karl Doghramji, Maurits Boon
OBJECTIVE: Drug induced sleep endoscopy (DISE) allows for preoperative evaluation of the specific site and character of upper airway obstruction in obstructive sleep apnea (OSA). We aim to assess the impact DISE has on customizing the surgical plan and evaluate its role in surgical success. METHODS: We retrospectively reviewed patients undergoing surgery for OSA. We compared those patients undergoing preoperative DISE to those that did not to assess procedures performed and surgical outcomes...
April 1, 2017: Annals of Otology, Rhinology, and Laryngology
https://www.readbyqxmd.com/read/28395403/-distribution-of-electroencephalograph-power-density-in-patients-with-severe-obstructive-sleep-apnea-during-different-sleep-stages
#19
Y Deng, X Tian, B Y Chen, N Zhou, M Xia, W W Bai, M M Dou, X Y Liu
Objective: To investigate the variation of electroencephalograph(EEG) power density during different sleep stages in OSA for understanding of the mechanisms underlying the brain dysfunction in OSA as well as its earlier diagnosis and treatment. Methods: Sixteen-channel EEGs from OSA patients and normal controls in stage wake, sleep stage 1, sleep stage 2, sleep stage 3 and rapid eye movement stage were analyzed by time-frequency analysis method. The EEG power density in different frequency bands (including δ, θ, α, σ, β and γ) was respectively compared between the 2 groups...
April 12, 2017: Chinese Journal of Tuberculosis and Respiratory Diseases
https://www.readbyqxmd.com/read/28392811/prevalence-of-cardiovascular-disorders-in-iranian-patients-suffering-from-obstructive-sleep-apnea
#20
Gholamreza Shirani, Seyyedeh Pouya Morovati, Ahmad Reza Shamshiri, Mehdi Nouri, Narges Ezzati Givi, Mohammad Farhadi
OBJECTIVES: Obstructive sleep apnea (OSA) can lead to various cardiovascular disorders (CVD) such as hypertension. There is no documented data about this relationship among the Iranian population. The aim of this study was to obtain comprehensive information about the severity of OSA as a cause of CVD and its relationship with other important risk factors. MATERIALS AND METHODS: In this cross sectional study, we studied patients with OSA and apnea/hypopnea index of 5 or more...
June 2016: Journal of Dentistry of Tehran University of Medical Sciences
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