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https://www.readbyqxmd.com/read/29667882/new-doppler-imaging-technique-for-assessing-angiogenesis-in-breast-tumors-correlation-with-immunohistochemically-analyzed-microvessels-density
#1
Sewha Kim, Hye Jin Lee, Kyung Hee Ko, Ah Young Park, Jieun Koh, Hae Kyoung Jung
Background Microvessel density (MVD) is associated with grade and prognosis in breast tumors. However, conventional color Doppler flow (CDF) imaging has been limited to represent MVD of breast tumors. Purpose To evaluate whether a new Doppler imaging technique (AngioPLUS) can represent MVD of breast tumors. Material and Methods The institutional review board approved this retrospective study, and patients' informed consent was waived. CDF and AngioPLUS were available in pathologically confirmed 55 breast tumors of 53 women...
January 1, 2018: Acta Radiologica
https://www.readbyqxmd.com/read/29667880/motion-artifacts-lesion-type-and-parenchymal-enhancement-in-breast-mri-what-does-really-influence-diagnostic-accuracy
#2
Paola Clauser, Matthias Dietzel, Michael Weber, Clemens G Kaiser, Pascal At Baltzer
Background Motion artifacts can reduce image quality of breast magnetic resonance imaging (MRI). There is a lack of data regarding their effect on diagnostic estimates. Purpose To evaluate factors that potentially influence readers' diagnostic estimates in breast MRI: motion artifacts; amount of fibroglandular tissue; background parenchymal enhancement; lesion size; and lesion type. Material and Methods This Institutional Review Board-approved, retrospective, cross-sectional, single-center study included 320 patients (mean age = 55...
January 1, 2018: Acta Radiologica
https://www.readbyqxmd.com/read/29667115/biopsy-feasibility-trial-for-breast-cancer-pathologic-complete-response-detection-after-neoadjuvant-chemotherapy-imaging-assessment-and-correlation-endpoints
#3
Gaiane M Rauch, Henry M Kuerer, Beatriz Adrada, Lumarie Santiago, Tanya Moseley, Rosalind P Candelaria, Elsa Arribas, Jia Sun, Jessica W T Leung, Savitri Krishnamurthy, Wei T Yang
PURPOSE: This study was designed to present the secondary imaging endpoints of the trial for evaluating mammogram (MMG), ultrasound (US) and image guided biopsy (IGBx) assessment of pathologic complete response (pCR) in breast cancer (BC) patients undergoing neoadjuvant chemotherapy (NAC). METHODS: Patients with T1-3, N0-3, M0 triple-negative or HER2-positive BC who received NAC were enrolled in an Institutional Review Board-approved prospective, clinical trial...
April 17, 2018: Annals of Surgical Oncology
https://www.readbyqxmd.com/read/29666996/comparison-of-t2-relaxation-values-in-subtalar-cartilage-between-patients-with-lateral-instability-of-the-ankle-joint-and-healthy-volunteers
#4
Hyun Su Kim, Young Cheol Yoon, Ki Sun Sung, Min-Ji Kim, Soohyun Ahn
PURPOSE: To evaluate the difference between T2 relaxation values of the subtalar cartilage in lateral ankle instability patients and healthy volunteers. MATERIALS AND METHODS: This institutional review board-approved study included 27 preoperative magnetic resonance imaging (MRI) examinations of 26 patients who underwent Broström operations. Data of previously enrolled healthy volunteers (12 volunteers, 13 MRIs) were used as controls. Two radiologists independently measured T2 values in eight posterior subtalar joint cartilage compartments: central calcaneus anterior (CCA) and posterior (CCP), central talus anterior (CTA) and posterior (CTP), lateral calcaneus anterior (LCA) and posterior (LCP), and lateral talus anterior (LTA) and posterior (LTP)...
April 17, 2018: European Radiology
https://www.readbyqxmd.com/read/29665809/generating-evidence-for-health-policy-in-challenging-settings-lessons-learned-from-four-prevention-of-mother-to-child-transmission-of-hiv-implementation-research-studies-in-nigeria
#5
Nadia A Sam-Agudu, Muktar H Aliyu, Olusegun A Adeyemi, Frank Oronsaye, Bolanle Oyeledun, Amaka G Ogidi, Echezona E Ezeanolue
BACKGROUND: Implementation research (IR) facilitates health systems strengthening and optimal patient outcomes by generating evidence for scale-up of efficacious strategies in context. Thus, difficulties in generating IR evidence, particularly in limited-resource settings with wide disease prevention and treatment gaps, need to be anticipated and addressed. Nigeria is a priority country for the prevention of mother-to-child transmission of HIV (PMTCT). This paper analyses the experiences of four PMTCT IR studies in Nigeria, and proffers solutions to major challenges encountered during implementation...
April 17, 2018: Health Research Policy and Systems
https://www.readbyqxmd.com/read/29664796/long-term-outcomes-with-ifosfamide-based-hypofractionated-preoperative-chemoradiotherapy-for-extremity-soft-tissue-sarcomas
#6
Joseph Daniel Pennington, Fritz C Eilber, Frederick R Eilber, Arun S Singh, Jarred P Reed, Bartosz Chmielowski, Jeffrey J Eckardt, Susan V Bukata, Nicholas M Bernthal, Noah Federman, Scott D Nelson, Sarah M Dry, Pin-Chieh Wang, Michael Luu, Michael T Selch, Michael L Steinberg, Anusha Kalbasi, Mitchell Kamrava
OBJECTIVES: The objective of this study was to analyze outcomes for patients with soft tissue sarcoma of the extremities using neoadjuvant ifosfamide-based chemotherapy and hypofractionated reduced dose radiotherapy, followed by limb-sparing surgery. MATERIALS AND METHODS: An Institutional Review Board (IRB)-approved retrospective review of patients treated at a single institution between 1990 and 2013 was performed. In total, 116 patients were identified who received neoadjuvant ifosfamide-based chemotherapy and 28 Gy in 8 fractions of preoperative radiation (equivalent dose in 2 Gray fractions, 31...
April 16, 2018: American Journal of Clinical Oncology
https://www.readbyqxmd.com/read/29663025/imaging-appearance-of-well-differentiated-liposarcomas-with-myxoid-stroma
#7
Yoav Morag, Corrie Yablon, Monica Kalume Brigido, Jon Jacobson, David Lucas
OBJECTIVE: Describe the imaging appearance of well-differentiated liposarcoma with myxoid stroma (WDLMS) and correlate with histopathology. MATERIALS AND METHODS: A keyword search of the institution medical records was performed from 1 January 2000 to 30 June 2017. The histopathology slides of cases identified in this fashion were then reviewed by a pathologist. Additional cases were prospectively collected from extramural referrals and tumor boards. Diagnostic imaging studies of pathologically proven cases of WDLMS were then reviewed in consensus and correlated with pathology...
April 16, 2018: Skeletal Radiology
https://www.readbyqxmd.com/read/29662834/liver-stiffness-measured-by-two-dimensional-shear-wave-elastography-prognostic-value-after-radiofrequency-ablation-for-hepatocellular-carcinoma
#8
Dong Ho Lee, Jeong Min Lee, Jung-Hwan Yoon, Yoon Jun Kim, Jeong-Hoon Lee, Su Jong Yu, Joon Koo Han
Purpose: To evaluate the prognostic value of liver stiffness (LS) measured using two-dimensional (2D) shear-wave elastography (SWE) in patients with hepatocellular carcinoma (HCC) treated by radiofrequency ablation (RFA). Methods: The Institutional Review Board approved this retrospective study and informed consent was obtained from all patients. A total of 134 patients with up to 3 HCCs ≤5 cm who had undergone pre-procedural 2D-SWE prior to RFA treatment between January 2012 and December 2013 were enrolled...
March 2018: Liver Cancer
https://www.readbyqxmd.com/read/29662741/predictive-factors-for-the-outcome-of-surgical-treatment-of-lumbar-spondylolysis-in-young-sporting-individuals
#9
Ujjwal K Debnath, B E Scammell, Brian J C Freeman, Jeffrey R McConnell
Study Design: Retrospective consecutive case series. Objectives: Only few sporting individuals with symptomatic lumbar pars injuries require surgical repair and it is often difficult to predict the outcome following surgery. The factors that predict the outcome after direct repair of lumbar pars defect was evaluated clinically and statistically. The preoperative background variables both subjective and objective as well as radiological evaluation were used in a multiple regression model to find the strong predictors of postoperative outcome as measured by VAS (visual analogue scores), ODI (Oswestry Disability Index) and SF-36 (Short Form)...
April 2018: Global Spine Journal
https://www.readbyqxmd.com/read/29662728/breastfeeding-and-weaning-practices-in-urban-slums-of-southern-punjab-pakistan
#10
Khalil Ahmed, Muhammad Talha, Zainab Khalid, Mehvish Khurshid, Rizwan Ishtiaq
Objective Proper breastfeeding and weaning practices are effective ways of reducing childhood morbidity and mortality. This study aimed to find out breastfeeding and weaning practices among infants of six months to one year in urban slums of Bahawalpur city. By evaluating the knowledge and attitude of lactating mothers regarding their child feeding habits, modifications and specific interventions can be implemented to improve the breastfeeding and weaning practices of the area. Methods A cross-sectional descriptive study was carried out in the Shahdrah slums of Bahawalpur City after getting approval from the institutional review board of Quaid-e-Azam Medical College, Bahawalpur...
February 13, 2018: Curēus
https://www.readbyqxmd.com/read/29661526/a-retrieval-analysis-of-impingement-in-dual-mobility-liners
#11
Trevor P Scott, Lydia Weitzler, Anthony Salvatore, Timothy M Wright, Geoffrey H Westrich
BACKGROUND: Implant-related impingement is likely a major causative factor of total hip arthroplasty (THA) instability. Dual-mobility (DM) cups can theoretically improve stability in THA, but impingement rates with DM cups are not well studied. We examined retrieved DM THA liners to determine if less evidence existed for prosthetic impingement between the neck and the polyethylene liner than historical studies from our institution on fixed-bearing THAs. METHODS: DM components from 93 THAs were identified from 164 THAs whose DM components were revised between 2008 and 2015 through our institutional review board-approved implant retrieval program...
March 16, 2018: Journal of Arthroplasty
https://www.readbyqxmd.com/read/29661274/granular-cell-tumor-experience-at-a-comprehensive-cancer-center
#12
Ambria S Moten, Sujana Movva, Margaret von Mehren, Hong Wu, Nestor F Esnaola, Sanjay S Reddy, Jeffrey M Farma
BACKGROUND: Granular cell tumors (GCTs) are rare lesions occurring almost anywhere in the body. Multiple case reports have been published. However, there are very few large-scale studies regarding GCT. The aim of this study was to define characteristics, treatment patterns and outcomes of patients with GCT. METHODS: An institutional review board-approved retrospective chart review was performed. Descriptive statistics, chi-square analyses, and Kaplan-Meier survival estimates were produced...
June 2018: Journal of Surgical Research
https://www.readbyqxmd.com/read/29660052/side-to-side-and-end-to-side-double-anastomosis-using-the-parietal-branch-of-the-superficial-temporal-artery-a-novel-technique-for-extracranial-to-intracranial-bypass-surgery-3-dimensional-operative-video
#13
Gregory D Arnone, Ziad A Hage, Fady T Charbel
In this 3-dimensional video, we perform a side-to-side and end-to-side double anastomosis using the parietal-branch of the superficial temporal artery (STA) to provide flow augmentation in a symptomatic 59-yr-old male with bilateral internal carotid artery occlusion at the origin, and left M1 segment occlusion. The patient suffered multiple left hemispheric strokes despite maximal medical therapy and was found to have poor hemodynamic reserve in the left hemisphere during evaluation with regional and global blood oxygenation level-dependent functional magnetic resonance imaging with CO2-challenge as well as quantitative magnetic resonance angiography and noninvasive optimal vessel analysis pre- and post-acetazolamide challenge...
April 12, 2018: Operative Neurosurgery (Hagerstown, Md.)
https://www.readbyqxmd.com/read/29660051/resection-of-right-frontal-arteriovenous-malformation-3-dimensional-operative-video
#14
William T Couldwell
The video demonstrates resection of a Grade II Spetzler-Martin unruptured, medium-sized arteriovenous malformation (AVM). A young woman presented with headaches and seizures. The right frontal lesion measured 4.5 cm in largest dimension and had superficial venous drainage. Partial Onyx embolization, primarily of the anterior cerebral feeding arteries, was performed. Bone removal for exposure allowed identification of indentation from the large superficial draining vein. The video demonstrates careful microsurgical dissection on the AVM/brain interface, with selective interruption of feeding arteries circumferentially...
April 11, 2018: Operative Neurosurgery (Hagerstown, Md.)
https://www.readbyqxmd.com/read/29660010/costs-for-breast-cancer-care-in-the-military-health-system-an-analysis-by-benefit-type-and-care-source
#15
Yvonne L Eaglehouse, Janna Manjelievskaia, Stephanie Shao, Derek Brown, Keith Hofmann, Patrick Richard, Craig D Shriver, Kangmin Zhu
Introduction: Breast cancer care imposes a significant financial burden to U.S. healthcare systems. Health services factors, such as insurance benefit type and care source, may impact costs to the health system. Beneficiaries in the U.S. Military Health System (MHS) have universal healthcare coverage and access to a network of military facilities (direct care) and private practices (purchased care). This study aims to quantify and compare breast cancer care costs to the MHS by insurance benefit type and care source...
April 11, 2018: Military Medicine
https://www.readbyqxmd.com/read/29659947/pediatric-thoracic-trauma-in-iraq-and-afghanistan
#16
Ryan J Keneally, Cynthia H Shields, Albert Hsu, Howard I Prior, Kevin M Creamer
Introduction: The objective of this study is to review available data on pediatric thoracic trauma seen at U.S. military treatment facilities in Iraq and Afghanistan and describe the scope of injuries, patterns seen, and associated mortality. The results were compared with adults injured in Iraq and Afghanistan and other reports of pediatric thoracic trauma in the literature. Materials and Methods: The investigators received approval from the Uniformed Services University of the Health Sciences' institutional review board before the study...
April 6, 2018: Military Medicine
https://www.readbyqxmd.com/read/29659429/spectral-detector-computed-tomography-pulmonary-angiography-improved-diagnostic-assessment-and-automated-estimation-of-window-settings-angiography-of-pulmonary-arteries-from-novel-spectral-detector-computed-tomography-provides-improved-image-quality-if-settings
#17
Nils Große Hokamp, Rivka Kessner, Steven Van Hedent, Frank Philipp Graner, Amit Gupta, Robert Gilkeson
OBJECTIVE: This study aimed to evaluate image quality (IQ) of virtual monoenergetic images (VMIs) from novel spectral detector computed tomography angiography of the pulmonary arteries and to identify appropriate window settings for each kiloelectron volt level. MATERIALS: Forty consecutive patients were included in this institutional review board-approved, Health Insurance Portability and Accountability Act-compliant study.Signal- and contrast-to-noise ratios were calculated within the pulmonary trunk, and pulmonary/lobar/segmental arteries were calculated...
April 13, 2018: Journal of Computer Assisted Tomography
https://www.readbyqxmd.com/read/29659424/utility-of-magnetic-resonance-imaging-for-predicting-severity-of-sciatic-nerve-injury
#18
Shivani Ahlawat, Allan J Belzberg, Laura M Fayad
OBJECTIVE: This study aimed to investigate the diagnostic accuracy of magnetic resonance (MR) imaging for categorizing sciatic peripheral nerve injury (PNI) as high-grade (Sunderland grades IV-V) or low-grade (Sunderland grades I-III) PNI. METHODS: In this institutional review board-approved, Health Insurance Portability and Accountability Act-compliant retrospective study, consecutive MR imaging of the pelvis and thighs, performed for the evaluation of traumatic sciatic neuropathy, was reviewed for sciatic nerve signal intensity, size, architectural distortion, bulbous enlargement, perineural fibrosis, discontinuity, and muscle denervation changes...
April 13, 2018: Journal of Computer Assisted Tomography
https://www.readbyqxmd.com/read/29657891/stereotactic-radiosurgery-for-primary-tumors-of-the-spine-and-spinal-cord-%C3%A2
#19
Erinma Elibe, David Boyce-Fappiano, Samuel Ryu, M Salim Siddiqui, Ian Lee, Jack Rock, Farzan Siddiqui
Purpose: The purpose of this study was to evaluate the role of stereotactic radiosurgery in the treatment of primary tumors of the spine and spinal cord. Methods: An Institutional Review Board approved retrospective analysis of 30 patients with primary spine tumors treated at a single institution was performed. Post-treatment pain, neurological, and radiographic responses were the endpoints. Results: Nine patients were treated for benign tumors, and 21 patients were treated for malignant tumors...
2018: Journal of Radiosurgery and SBRT
https://www.readbyqxmd.com/read/29657862/a-review-of-social-media-methods-and-lessons-learned-from-the-national-children-s-study
#20
REVIEW
Amelia Burke-Garcia, Kate Winseck, Leslie Cooke Jouvenal, David Hubble, Kathryn M Kulbicki
Introduction: Given the reach and influence of social media, the National Children's Study Vanguard Study evaluated the feasibility, acceptability, and cost of using social media to support participant retention. Methods: We describe a social media experiment designed to assess the impact of social media on participant retention, discuss several key considerations for integrating social media into longitudinal research, and review factors that may influence engagement in research-related social media...
August 2017: Journal of Clinical and Translational Science
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