keyword
MENU ▼
Read by QxMD icon Read
search

Institutional review boards

keyword
https://www.readbyqxmd.com/read/29029314/small-aneurysms-account-for-the-majority-and-increasing-percentage-of-aneurysmal-subarachnoid-hemorrhage-a-25-year-single-institution-study
#1
Matthew T Bender, Haley Wendt, Thomas Monarch, Narlin Beaty, Li-Mei Lin, Judy Huang, Alexander Coon, Rafael J Tamargo, Geoffrey P Colby
BACKGROUND: Prospective studies of unruptured aneurysms have shown very low rates of rupture for small aneurysms (<10 mm) and suggested that the risk of treatment outweighs benefit. However, common clinical practice shows that patients with aneurysmal subarachnoid hemorrhage (aSAH) frequently have small aneurysms. OBJECTIVE: To investigate trends in size and location of ruptured aneurysms over a 25-yr period. METHODS: A prospective, Institutional Review Board-approved database of all patients presenting to our institution with aSAH from 1991 to 2016 was analyzed...
October 6, 2017: Neurosurgery
https://www.readbyqxmd.com/read/29029287/survival-in-response-to-multimodal-therapy-in-anaplastic-thyroid-cancer
#2
Naiyarat Prasongsook, Aditi Kumar, Ashish V Chintakuntlawar, Robert L Foote, Jan Kasperbauer, Julian Molina, Yolanda Garces, Daniel Ma, Michelle A Neben Wittich, Joseph Rubin, Ronald Richardson, John Morris, Ian Hay, Vahab Fatourechi, Bryan McIver, Mabel Ryder, Geoffrey Thompson, Clive Grant, Melanie Richards, Thomas J Sebo, Michael Rivera, Vera Suman, Sarah M Jenkins, Robert C Smallridge, Keith C Bible
Context: Historical outcomes in anaplastic thyroid cancer (ATC) have been dismal. Objective: To define whether initial intensive multimodal therapy combining surgery, chemotherapy, and radiation might be associated with improved ATC survival. Design: Multimodal therapy was offered to all newly-diagnosed ATC patients treated at the Mayo Clinic, 2003-2015; multimodal vs. palliative therapy was individualized considering clinical status and patient preferences...
October 5, 2017: Journal of Clinical Endocrinology and Metabolism
https://www.readbyqxmd.com/read/29028467/expanding-ethics-review-processes-to-include-community-level-protections-a-case-study-from-flint-michigan
#3
Kent D Key
As the Flint community endeavors to recover and move forward in the aftermath of the Flint water crisis, distrust of scientific and governmental authorities must be overcome. Future community engagement in research will require community-level protections ensuring that no further harm is done to the community. A community ethics review explores risks and benefits and complements institutional review board (IRB) review. Using the case of Flint, I describe how community-level ethical protections can reestablish a community's trust...
October 1, 2017: AMA Journal of Ethics
https://www.readbyqxmd.com/read/29027400/surgical-and-oncologic-outcomes-after-robotic-radical-hysterectomy-as-compared-to-open-radical-hysterectomy-in-the-treatment-of-early-cervical-cancer
#4
Chirag A Shah, Tiffany Beck, John B Liao, Nadia V Giannakopoulos, Dan Veljovich, Pam Paley
OBJECTIVE: The use of robotic radical hysterectomy has greatly increased in the treatment of early stage cervical cancer. We sought to compare surgical and oncologic outcomes of women undergoing robotic radical hysterectomy compared to open radical hysterectomy. METHODS: The clinic-pathologic, treatment, and recurrence data were abstracted through an Institutional Review Board-approved protocol at 2 separate large tertiary care centers in Seattle, Swedish Medical Center and the University of Washington...
November 2017: Journal of Gynecologic Oncology
https://www.readbyqxmd.com/read/29026353/association-of-body-mass-index-and-postoperative-acute-kidney-injury-in-patients-undergoing-laparoscopic-surgery
#5
Maged Y Argalious, Natalya Makarova, Alexander Leone, Jacek Cywinski, Ehab Farag
BACKGROUND: Whether the deleterious effects of carbon dioxide pneumoperitoneum on the kidneys are exacerbated in the obese population remains unknown. We hypothesized that increased body mass index (BMI) is associated with an increased incidence of postoperative acute kidney injury (AKI) in patients undergoing noncardiac laparoscopic surgery. METHODS: Following institutional review board approval, we analyzed data on 8,543 adult patients with American Society of Anesthesiologists physical status scores of I-IV who had inpatient noncardiac laparoscopic surgery from 2005-2014...
2017: Ochsner Journal
https://www.readbyqxmd.com/read/29025276/once-daily-versus-twice-daily-enoxaparin-for-the-treatment-of-acute-venous-thromboembolism-in-cancer-patients
#6
Katherine Fuller, Stephanie Malecki, Lisa Anselmo, Matthew E Borrego, Bernadette Jakeman, Allison Burnett
BACKGROUND: No randomized controlled trials have investigated enoxaparin once versus twice daily for venous thromboembolism (VTE) treatment in cancer patients. OBJECTIVE: To compare the safety and efficacy of enoxaparin 1 mg/kg twice daily versus enoxaparin 1.5 mg/kg/day for the treatment of acute VTE in cancer patients. METHODS: This was a single-center, retrospective, observational cohort study. Adults with active cancer and an acute VTE were included...
October 1, 2017: Annals of Pharmacotherapy
https://www.readbyqxmd.com/read/29025089/oral-ketamine-for-acute-pain-management-after-amputation-surgery
#7
Asokumar Buvanendran, Jeffrey S Kroin, Arvind Rajagopal, Sherry J Robison, Mario Moric, Kenneth J Tuman
Objective: Intravenous ketamine has been shown to provide postoperative analgesia in many clinical trials, in particular to reduce opioid consumption. The primary objective of this pilot study is to determine if multiple dosing over a three-day perioperative period with oral ketamine is a safe treatment method for acute pain after amputation surgery. Methods: Three consented subjects (age 57-60 years) undergoing elective amputation of the lower extremity were included in the study (Institutional Review Board and Food and Drug Administration Investigational New Drug approved)...
September 14, 2017: Pain Medicine: the Official Journal of the American Academy of Pain Medicine
https://www.readbyqxmd.com/read/29020709/absorbaseal%C3%A2-vascular-closure-device-a-novel-device-for-hemostasis-following-interventional-peripheral-vascular-procedures
#8
Emily Benham, Koen Deloose, Joren Callaert, Marc Bosiers, Tiffany Cox, Amy Lincourt, B Todd Heniford
INTRODUCTION: Vascular closure devices (VCDs) are designed to achieve rapid hemostasis during percutaneous coronary and peripheral vascular procedures. Studies demonstrate that VCDs improve time to hemostasis (TTH) and time to ambulation (TTA) in comparison to standard manual compression. The available products, however, typically have 13-17 steps in their application, often require hemostatic collagen or other agents as part of the process, and can result in significant scarring at the puncture site that can impact future access...
October 12, 2017: Surgical Technology International
https://www.readbyqxmd.com/read/29019891/study-protocol-for-a-randomized-controlled-pilot-trial-on-the-semiocclusive-treatment-of-fingertip-amputation-injuries-using-a-novel-finger-cap
#9
Jurek Schultz, Susann Leupold, Xina Grählert, Roland Pfeiffer, Uta Schwanebeck, Percy Schröttner, Barbara Djawid, Wladislav Artsimovich, Karol Kozak, Guido Fitze
INTRODUCTION: Fingertip amputation injuries are common in all ages. Conservatively treated fingertips can regenerate skin and soft tissues to form a functionally and cosmetically excellent new fingertip. Little is known about this ability that, in humans, is confined to the fingertips. Even less is known about the role of the bacteria that regularly colonize these wounds without negative impact on regeneration and healing.As an alternative to surgery, self-adhesive film dressings are commonly used to establish a wet chamber around the injury...
October 2017: Medicine (Baltimore)
https://www.readbyqxmd.com/read/29019706/institutional-scientific-review-of-cancer-clinical-research-protocols-a-unique-requirement-that-affects-activation-timelines
#10
Ning Ning, Jingsheng Yan, Martin F Dietrich, Xian-Jin Xie, David E Gerber
PURPOSE: The National Cancer Institute (NCI) requirement that clinical trials at NCI-designated cancer centers undergo institutional scientific review in addition to institutional review board evaluation is unique among medical specialties. We sought to evaluate the effect of this process on protocol activation timelines. METHODS: We analyzed oncology clinical trials that underwent full board review by the Harold C. Simmons Comprehensive Cancer Center Protocol Review and Monitoring Committee (PRMC) from January 1, 2009, through June 30, 2013...
October 11, 2017: Journal of Oncology Practice
https://www.readbyqxmd.com/read/29018070/hypothermic-oxygenated-machine-perfusion-hope-for-orthotopic-liver-transplantation-of-human-liver-allografts-from-extended-criteria-donors-ecd-in-donation-after-brain-death-dbd-a-prospective-multicentre-randomised-controlled-trial-hope-ecd-dbd
#11
Zoltan Czigany, Wenzel Schöning, Tom Florian Ulmer, Jan Bednarsch, Iakovos Amygdalos, Thorsten Cramer, Xavier Rogiers, Irinel Popescu, Florin Botea, Jiří Froněk, Daniela Kroy, Alexander Koch, Frank Tacke, Christian Trautwein, Rene H Tolba, Marc Hein, Ger H Koek, Cornelis H C Dejong, Ulf Peter Neumann, Georg Lurje
INTRODUCTION: Orthotopic liver transplantation (OLT) has emerged as the mainstay of treatment for end-stage liver disease. In an attempt to improve the availability of donor allografts and reduce waiting list mortality, graft acceptance criteria were extended increasingly over the decades. The use of extended criteria donor (ECD) allografts is associated with a higher incidence of primary graft non-function and/or delayed graft function. As such, several strategies have been developed aiming at reconditioning poor quality ECD liver allografts...
October 10, 2017: BMJ Open
https://www.readbyqxmd.com/read/29016373/cancer-yield-of-incidental-breast-lesions-detected-on-chest-computed-tomography
#12
Terrance T Healey, Saurabh Agarwal, Ronak Patel, Lisa Ratanaprasatporn, Linda Ratanaprasatporn, Ana P Lourenco
OBJECTIVE: This study aimed to determine the cancer yield for abnormal breast findings initially identified on chest computed tomography (CT). MATERIALS AND METHODS: This institutional review board-approved, Health Insurance Portability and Accountability Act-compliant study retrospectively reviewed reports of 41,217 consecutive chest CT examinations done from January 1, 2006, to December 31, 2011, to identify those with breast findings noted in the impression of the report...
October 7, 2017: Journal of Computer Assisted Tomography
https://www.readbyqxmd.com/read/29016370/heavily-calcified-coronary-arteries-advanced-calcium-subtraction-improves-luminal-visualization-and-diagnostic-confidence-in-dual-energy-coronary-computed-tomography-angiography
#13
Domenico De Santis, Kwang Nam Jin, U Joseph Schoepf, Katharine L Grant, Carlo N De Cecco, John W Nance, Thomas J Vogl, Andrea Laghi, Moritz H Albrecht
OBJECTIVES: The aim of this study was to evaluate a prototype dual-energy computed tomography calcium subtraction algorithm and its impact on luminal visualization in patients with heavily calcified coronary arteries. MATERIALS AND METHODS: Twenty-nine patients (62% male; mean age, 64 ± 7 years) who had undergone dual-energy coronary computed tomography angiography were retrospectively included in this institutional review board-approved, Health Insurance Portability and Accountability Act-compliant study...
October 9, 2017: Investigative Radiology
https://www.readbyqxmd.com/read/28993391/evaluating-a-novel-integrated-community-of-care-icoc-for-patients-from-an-urbanised-low-income-community-in-singapore-using-the-participatory-action-research-par-methodology-a-study-protocol
#14
Lian Leng Low, Adlina Maulod, Kheng Hock Lee
INTRODUCTION: Poorer health outcomes and disproportionate healthcare use in socioeconomically disadvantaged patients is well established. However, there is sparse literature on effective integrated care interventions that specifically target these high-risk individuals. The Integrated Community of Care (ICoC) is a novel care model that integrates hospital-based transitional care with health and social care in the community for high-risk individuals living in socially deprived communities...
October 8, 2017: BMJ Open
https://www.readbyqxmd.com/read/28993074/obtaining-waivers-of-parental-consent-a-strategy-endorsed-by-gay-bisexual-and-queer-adolescent-males-for-health-prevention-research
#15
Dalmacio Flores, Ross McKinney, Joyell Arscott, Julie Barroso
BACKGROUND: Requiring parental consent in studies with sexual minority youth (SMY) can sometimes be problematic as participants may have yet to disclose their sexual orientation, may not feel comfortable asking parents' permission, and may promote a self-selection bias. PURPOSE: We discuss rationale for waiving parental consent, strategies to secure waivers from review boards, and present participants' feedback on research without parents' permission. METHODS: We share our institutional review board proposal in which we made a case that excluding SMY from research violates ethical research principles, does not recognize their autonomy, and limits collection of sexuality data...
September 18, 2017: Nursing Outlook
https://www.readbyqxmd.com/read/28991760/centenary-of-the-birth-of-academician-prof-dr-isak-tadzer-founder-of-the-pathophysiology-and-nuclear-medicine-in-macedonia
#16
Borislav Karanfilski
Academician Prof. Dr. Isak Tadzer was born a hundred years ago on December 24, 1916 in Sofia. He completed the primary and secondary education at the German College in Sofia. In 1935 he began his studies at the Medical Faculty in Vienna, which he had to stop because of the annexation of Austria to Germany in 1938. He returned to Bulgaria where he continued his studies and graduated from the Medical Faculty in Sofia in 1941. During the War, 1941-1944, he was forcedly mobilized and he worked as a doctor in several villages...
September 1, 2017: Prilozi (Makedonska Akademija Na Naukite i Umetnostite. Oddelenie za Medicinski Nauki)
https://www.readbyqxmd.com/read/28990417/risk-indicators-and-effects-of-hypertension-on-hiv-aids-disease-progression-among-patients-seen-at-kenyatta-hospital-hiv-care-center
#17
Angeline Chepchirchir, Walter Jaoko, Joshua Nyagol
There is paucity of data on prevalence of hypertension and its effects on HIV/AIDS progression among patients at Kenyatta National Hospital (KNH), Kenya. This was a cross sectional study conducted between January and May 2015 at the KNH HIV Care Centre. Ethical approval was obtained from institutional ethics review board. HIV positive adult patients were recruited sequentially, and written informed consent obtained from each participant. Systematic sampling was used to select participants who were screened for blood pressure, body mass index (BMI) and lifestyle characteristics...
October 9, 2017: AIDS Care
https://www.readbyqxmd.com/read/28989010/global-health-education-for-medical-students-when-learning-objectives-include-research
#18
Alison M Bales, Anthony R Oddo, David J Dennis, Robert C Siska, Echo VanderWal, Harry VanderWal, Nompumelelo Dlamini, Ronald J Markert, Mary C McCarthy
BACKGROUND: The Luke Commission, a provider of comprehensive mobile health outreach in rural Swaziland, focuses on human immunodeficiency virus testing and prevention, including the performance of over 100 circumcisions weekly. Educational objectives for medical student global health electives are essential. Learning research methodology while engaging in clinical activities reinforces curriculum goals. Medical care databases can produce clinically significant findings affecting international health policy...
October 5, 2017: Journal of Surgical Education
https://www.readbyqxmd.com/read/28987694/on-the-effect-of-computed-tomography-resolution-to-distinguish-between-abdominal-aortic-aneurysm-wall-tissue-and-calcification-a-proof-of-concept
#19
H E Barrett, E M Cunnane, J M O Brien, M A Moloney, E G Kavanagh, M T Walsh
PURPOSE: The purpose of this study is to determine the optimal target CT spatial resolution for accurately imaging abdominal aortic aneurysm (AAA) wall characteristics, distinguishing between tissue and calcification components, for an accurate assessment of rupture risk. MATERIALS AND METHODS: Ruptured and non-ruptured AAA-wall samples were acquired from eight patients undergoing open surgical aneurysm repair upon institutional review board approval and informed consent was obtained from all patients...
October 2017: European Journal of Radiology
https://www.readbyqxmd.com/read/28987684/material-density-iodine-images-in-dual-energy-ct-detection-and-characterization-of-hypervascular-liver-lesions-compared-to-magnetic-resonance-imaging
#20
Daniela Muenzel, Grace C Lo, Hei Shun Yu, Anushri Parakh, Manuel Patino, Avinash Kambadakone, Ernst J Rummeny, Dushyant V Sahani
PURPOSE: To determine the diagnostic potential of Material Density (MD) iodine images in dual-energy CT (DECT) for the detection and characterization of hypervascular liver lesions compared to monenergetic 65keV images, using MRI as the standard. MATERIALS AND METHODS: The study complied with HIPAA guidelines and was approved by the institutional review board. Fifty-two patients (36 men, 16 women; age range, 29-87 years) with 236 hypervascular liver lesions (benign, n=31; malignant, n=205; mean diameter, 29...
October 2017: European Journal of Radiology
keyword
keyword
86132
1
2
Fetch more papers »
Fetching more papers... Fetching...
Read by QxMD. Sign in or create an account to discover new knowledge that matter to you.
Remove bar
Read by QxMD icon Read
×

Search Tips

Use Boolean operators: AND/OR

diabetic AND foot
diabetes OR diabetic

Exclude a word using the 'minus' sign

Virchow -triad

Use Parentheses

water AND (cup OR glass)

Add an asterisk (*) at end of a word to include word stems

Neuro* will search for Neurology, Neuroscientist, Neurological, and so on

Use quotes to search for an exact phrase

"primary prevention of cancer"
(heart or cardiac or cardio*) AND arrest -"American Heart Association"