keyword
MENU ▼
Read by QxMD icon Read
search

Institutional review boards

keyword
https://www.readbyqxmd.com/read/29907488/correlation-of-regional-lung-ventilation-and-gas-transfer-to-red-blood-cells-implications-for-functional-avoidance-radiation-therapy-planning
#1
Leith J Rankine, Ziyi Wang, Bastiaan Driehuys, Lawrence B Marks, Chris R Kelsey, Shiva K Das
PURPOSE: To investigate the degree to which lung ventilation and gas exchange are regionally correlated, using the emerging technology of hyperpolarized (HP)-129 Xe magnetic resonance imaging (MRI). METHODS AND MATERIALS: Hyperpolarized-129 Xe MRI studies were performed on 17 institutional review board-approved human subjects, including 13 healthy volunteers, 1 emphysema patient, and 3 non-small cell lung cancer patients imaged before and approximately 11 weeks after radiation therapy (RT)...
April 14, 2018: International Journal of Radiation Oncology, Biology, Physics
https://www.readbyqxmd.com/read/29907419/comparison-of-breast-density-between-synthesized-versus-standard-digital-mammography
#2
Irfanullah Haider, Matthew Morgan, Anna McGow, Matthew Stein, Maryam Rezvani, Phoebe Freer, Nan Hu, Laurie Fajardo, Nicole Winkler
PURPOSE: To evaluate perceptual difference in breast density classification using synthesized mammography (SM) compared with standard or full-field digital mammography (FFDM) for screening. MATERIALS AND METHODS: This institutional review board-approved, retrospective, multireader study evaluated breast density on 200 patients who underwent baseline screening mammogram during which both SM and FFDM were obtained contemporaneously from June 1, 2016, through November 30, 2016...
June 12, 2018: Journal of the American College of Radiology: JACR
https://www.readbyqxmd.com/read/29907398/using-correlative-properties-of-neighboring-pixels-to-enhance-contrast-to-noise-ratio-of-abnormal-hippocampus-in-patients-with-intractable-epilepsy-and-mesial-temporal-sclerosis
#3
Matthew S Parsons, Aseem Sharma, Charles Hildebolt
RATIONALE AND OBJECTIVES: To test whether an image-processing algorithm can aid in visualization of mesial temporal sclerosis on magnetic resonance imaging by selectively increasing contrast-to-noise ratio (CNR) between abnormal hippocampus and normal brain. MATERIALS AND METHODS: In this Institutional Review Board-approved and Health Insurance Portability and Accountability Act-compliant study, baseline coronal fluid-attenuated inversion recovery images of 18 adults (10 females, eight males; mean age 41...
June 12, 2018: Academic Radiology
https://www.readbyqxmd.com/read/29907216/liquid-chromatography-mass-spectroscopy-in-the-diagnosis-of-biliary-atresia-in-children-with-hyperbilirubinemia
#4
Jamie Golden, Jessica A Zagory, Michael Fenlon, Catherine J Goodhue, Yi Xiao, Xiaowei Fu, Kasper S Wang, Christopher P Gayer
BACKGROUND: Biliary atresia (BA) is difficult to distinguish from other causes of cholestasis. We evaluated the use of liquid chromatography-mass spectroscopy (LC-MS) and bile acid profiles in the rapid, noninvasive diagnosis of BA. MATERIALS AND METHODS: Following Institutional Animal Care and Use Committee and Institutional Review Board approval, we used LC-MS to measure 26 bile acids in serum and stool samples from experimental models of BA and in urine, stool, and serum samples from non-cholestatic and cholestatic human infants...
August 2018: Journal of Surgical Research
https://www.readbyqxmd.com/read/29906528/cd300c-co-stimulates-ige-mediated-basophils-activation-and-its-expression-is-increased-in-cow%C3%A2-s-milk-allergy
#5
Olatz Zenarruzabeitia, Joana Vitallé, Iñigo Terrén, Ane Orrantia, Itziar Astigarraga, Leire Dopazo, Carlos Gonzalez, Laura Santos-Díez, Carlos Tutau, Pedro M Gamboa, Agurtzane Bilbao, Francisco Borrego
BACKGROUND: Basophils express high-affinity IgE receptors (FcεRI), which play an essential role in allergic diseases. To design promising immunomodulatory therapies, it is important to characterize new cell surface receptors that modulate immunoglobulin (Ig)E-mediated basophil activation threshold. OBJECTIVES: To analyze the expression of CD300 receptors on human basophils and their implication in IgE-mediated basophil activation processes. METHODS: Blood samples from healthy and cow´s milk allergic patients were collected through the Basque Biobank under an institutional review board-approved protocol...
June 12, 2018: Journal of Allergy and Clinical Immunology
https://www.readbyqxmd.com/read/29903924/detection-and-characteristics-of-temporal-encephaloceles-in-patients-with-refractory-epilepsy
#6
Z M Campbell, J M Hyer, S Lauzon, L Bonilha, M V Spampinato, M Yazdani
BACKGROUND AND PURPOSE: Temporal encephaloceles are increasingly visualized during neuroimaging assessment of individuals with refractory temporal lobe epilepsy, and their identification could indicate an intracranial abnormality that may be related to a potential seizure focus. Careful review by an experienced neuroradiologist may yield improved detection of TEs, and other clinical, neurophysiologic, and radiologic findings may predict their presence. MATERIALS AND METHODS: Data were reviewed retrospectively in patients at our institution who were presented at a multidisciplinary conference for refractory epilepsy between January 1, 2010, and December 31, 2016...
June 14, 2018: AJNR. American Journal of Neuroradiology
https://www.readbyqxmd.com/read/29903698/characteristics-of-adults-use-of-facebook-and-the-potential-impact-on-health-behavior-secondary-data-analysis
#7
Kelly Bosak, Shin Hye Park
BACKGROUND: Social influences are a primary factor in the adoption of health behaviors. Social media platforms, such as Facebook, disseminate information, raise awareness, and provide motivation and support for positive health behaviors. Facebook has evolved rapidly and is now a part of many individuals' daily routine. The high degree of individual engagement and low attrition rate of this platform necessitate consideration for a potentially positive impact on health behavior. OBJECTIVE: The aim of this paper is to investigate the use of Facebook by adults...
June 14, 2018: Interactive Journal of Medical Research
https://www.readbyqxmd.com/read/29902956/the-real-time-irb-a-collaborative-innovation-to-decrease-irb-review-time
#8
Ryan Spellecy, Ann Marie Eve, Emily R Connors, Reza Shaker, David C Clark
Lengthy review times for institutional review boards (IRBs) are a well-known barrier to research. In response to numerous calls to reduce review times, we devised "Real-Time IRB," a process that drastically reduces IRB review time. In this, investigators and study staff attend the IRB meeting and make changes to the protocol while the IRB continues its meeting, so that final approval can be issued at the meeting. This achieved an overall reduction in time from submission to the IRB to final approval of 40%...
June 1, 2018: Journal of Empirical Research on Human Research Ethics: JERHRE
https://www.readbyqxmd.com/read/29902953/irb-oversight-of-patient-centered-outcomes-research-a-national-survey-of-irb-chairpersons
#9
Joel S Weissman, Eric G Campbell, I Glenn Cohen, Holly Fernandez Lynch, Emily A Largent, Avni Gupta, Ronen Rozenblum, Melissa Abraham, Karen Spikes, Maureen Fagan, Martie Carnie
Patient-centered outcomes research (PCOR) is becoming increasingly common. However, there is little evidence regarding what novel ethical challenges, if any, are posed by PCOR with relevance to institutional review board (IRB) oversight and human subjects protections. This article reports the results of a national survey of all IRB chairpersons from research-intensive institutions in the United States. Findings address the responsibilities of IRBs and the challenges associated with PCOR review and oversight...
June 1, 2018: Journal of Empirical Research on Human Research Ethics: JERHRE
https://www.readbyqxmd.com/read/29901722/genitourinary-surgical-workload-at-deployed-u-s-facilities-in-iraq-and-afghanistan-2002-2016
#10
Caryn A Turner, Jean A Orman, Zsolt T Stockinger, Steven J Hudak
Introduction: Genitourinary surgery constitutes approximately 1.15% of procedures performed for combat injuries. During forward deployment, surgeons usually deploy without urology support. To better understand the training and skills maintenance needs for genitourinary procedures by describing in detail the genitourinary surgical workload during 15 years of combat operations and compare our findings with those from previously published articles. Material and Methods: A retrospective analysis of the Department of Defense Trauma Registry (DoDTR) was performed for all Roles 2 and 3 medical treatment facilities in Iraq and Afghanistan, from January 2002 to May 2016...
June 13, 2018: Military Medicine
https://www.readbyqxmd.com/read/29901610/chinese-herbal-medicine-for-the-treatment-of-henoch-sch%C3%A3-nlein-purpura-nephritis-in-children-a-prospective-cohort-study-protocol
#11
Jun Zhang, Jing Lv, Shuang Pang, Xiaohong Bai, Fang Yuan, Yubin Wu, Hong Jiang, Guanqi Yang, Shaoqing Zhang
INTRODUCTION: Henoch-Schönlein purpura nephritis (HSPN) involves the renal impairment of Henoch-Schönlein purpura and can easily relapse into life-threatening late nephropathy in severe cases. Although there is a lack of validated evidence for its effectiveness, Chinese herbal medicine (CHM) is one of the most commonly used methods in China to treat HSPN. It is thus need to report the protocol of a prospective cohort trial using CHM to investigate the effectiveness, safety and advantages for children with HSPN...
June 2018: Medicine (Baltimore)
https://www.readbyqxmd.com/read/29901509/magnetic-resonance-imaging-features-of-endometrial-polyps-frequency-of-occurrence-and-interobserver-reliability
#12
Patricia Balcacer, Kirsten A Cooper, Steffen Huber, Michael Spektor, Jay K Pahade, Gary M Israel
OBJECTIVE: This study aimed to evaluate magnetic resonance imaging (MRI) features and interobserver agreement of endometrial polyps. METHODS: After institutional review board approval, our database was searched for women older than 18 years who underwent MRI pelvis and pelvic surgical intervention from 2012 to 2016. Seventy-two patients with polyps and 75 controls composed the study cohort. Two radiologists evaluated the MRIs retrospectively for polyps. Polyp characteristics and enhancement were assessed...
June 12, 2018: Journal of Computer Assisted Tomography
https://www.readbyqxmd.com/read/29900820/outcomes-of-renal-salvage-for-penetrating-renal-trauma-a-single-institution-experience
#13
S Johar Raza, Perry Xu, Justin Barnes, Robert Fisher, Allison May, Oussama Darwish, Brian Dang, Prajakta Adsul, Carl A Freeman, Sameer A Siddiqui
INTRODUCTION: Conservative management of penetrating renal trauma is emerging, with data originating from centers with variable level of trauma care. This study reviews the outcomes of renal salvage after penetrating trauma at a level I trauma center. MATERIALS AND METHODS: An institutional review board approved trauma registry at Saint Louis University Hospital was retrospectively analyzed, for patients with penetrating renal trauma from 2009 to 2014. Patients were divided into nephrectomy group (NG) or non-nephrectomy group (non-NG), and compared...
June 2018: Canadian Journal of Urology
https://www.readbyqxmd.com/read/29898866/back-to-the-future-the-cecil-culp-technique-for-salvage-penile-reconstructive-procedures
#14
D A Weiss, C J Long, J R Frazier, A R Shukla, A K Srinivasan, T F Kolon, H DiCarlo, J P Gearhart, D A Canning
INTRODUCTION: Re-operative penile reconstruction is challenging and requires tension-free skin closure. The repair popularized by Cecil and Culp in the 1940s, using the scrotum to provide a temporary vascularized bed for complex hypospadias repairs, fell out of favor due to temporal trends towards single-stage repairs and concern for utilizing hair-bearing skin on the penile shaft. OBJECTIVE: It was hypothesized that a modified Cecil-Culp (CC) concept of penile scrotalization, leaving the penis attached to the scrotum for 1 year rather than 6 weeks as originally described, improves outcomes with this reconstruction for ventral skin deficiency or poor vascular support...
May 30, 2018: Journal of Pediatric Urology
https://www.readbyqxmd.com/read/29898002/qtc-interval-prolongation-in-critically-ill-patients-prevalence-risk-factors-and-associated-medications
#15
Flávia Medeiros Fernandes, Eliane Pereira Silva, Rand Randall Martins, Antonio Gouveia Oliveira
PURPOSE: To investigate the prevalence and risk factors of acquired long QT syndrome (LQTS) on admission to a general Intensive Care Unit (ICU), and to assess the risk of LQTS associated with prescribed medications. METHODS: Prospective observational, cross-sectional study approved by the Institutional Review Board. Between May 2014 and July 2016, 412 patients >18 years-old consecutively admitted to the ICU of a university hospital were included. LQTS was defined as a QT interval on the admission electrocardiogram corrected using Bazett's formula (QTc) >460 ms for men and >470 ms for women...
2018: PloS One
https://www.readbyqxmd.com/read/29895651/telemedicine-for-the-management-of-neuropsychiatric-symptoms-in-long-term-care-facilities-the-detect-study-methods-of-a-cluster-randomised-controlled-trial-to-assess-feasibility
#16
Antoine Piau, Fati Nourhashemi, Adélaïde De Mauléon, Achille Tchalla, Claude Vautier, Bruno Vellas, Maryline Duboue, Nadège Costa, Pierre Rumeau, Benoit Lepage, Maria Soto Martin
INTRODUCTION: Neuropsychiatric symptoms (NPSs) in elderly patients with dementia are frequent in long-term care facilities (LTCFs) and are associated with adverse events. Telemedicine is an emerging way to provide consultation and care to dependent LTCF residents who may not have easy access to specialty services. Several studies have evaluated telemedicine for dementia care but to date, no study has evaluated its impact in the management of NPS in patients with dementia living in LTCF...
June 12, 2018: BMJ Open
https://www.readbyqxmd.com/read/29895523/the-collaborative-role-of-north-american-departments-of-pediatrics-in-global-child-health
#17
REVIEW
Sophia P Gladding, Patrick T McGann, Andrea Summer, Christiana M Russ, Omolara T Uwemedimo, Martha Matamoros Aguilar, Rana Chakraborty, Molly Moore, Mary Lieh-Lai, Robert Opoka, Cynthia Howard, Chandy C John
Appeals for health equity call for departments of pediatrics to improve the health of all children including those from underserved communities in North America and around the world. Consequently, North American (NA) departments of pediatrics have a role in global child health (GCH) which focuses on providing health care to underserved children worldwide. In this review, we describe how NA departments of pediatrics can collaboratively engage in GCH education, clinical practice, research, and advocacy and summarize best practices, challenges, and next steps for engaging in GCH in each of these areas...
June 12, 2018: Pediatrics
https://www.readbyqxmd.com/read/29895289/intravenous-morphine-versus-intravenous-paracetamol-after-cardiac-surgery-in-neonates-and-infants-a-study-protocol-for-a-randomized-controlled-trial
#18
Gerdien A Zeilmaker-Roest, Joost van Rosmalen, Monique van Dijk, Erik Koomen, Nicolaas J G Jansen, Martin C J Kneyber, Sofie Maebe, Greet van den Berghe, Dirk Vlasselaers, Ad J J C Bogers, Dick Tibboel, Enno D Wildschut
BACKGROUND: Morphine is worldwide the analgesic of first choice after cardiac surgery in children. Morphine has unwanted hemodynamic and respiratory side effects. Therefore, post-cardiac surgery patients may potentially benefit from a non-opioid drug for pain relief. A previous study has shown that intravenous (IV) paracetamol is effective and opioid-sparing in children after major non-cardiac surgery. The aim of the study is to test the hypothesis that intermittent IV paracetamol administration in children after cardiac surgery will result in a reduction of at least 30% of the cumulative morphine requirement...
June 13, 2018: Trials
https://www.readbyqxmd.com/read/29894441/nurse-practitioner-triage-of-the-neurosurgical-patient-a-patient-centered-care-delivery-model
#19
Jody L Miniard, Kathleen Ballman
BACKGROUND: Nurse practitioners (NPs) are helping to bridge the gap not only in primary care but also in specialty practice. In an outpatient, neurosurgical spinal clinic in the midwest, patient volume exceeded provider availability, and to rectify this problem, a proposal for an NP triage system and an NP-led spinal clinic was presented. PURPOSE: The aim of this project was to use NPs to facilitate patient triage in an outpatient neurosurgical practice to expedite patients' access to care and ultimately improve patient satisfaction, outcomes, and healthcare expenditure...
June 12, 2018: Journal of Neuroscience Nursing: Journal of the American Association of Neuroscience Nurses
https://www.readbyqxmd.com/read/29891569/erectile-dysfunction-as-an-independent-predictor-of-future-cardiovascular-events-the-multi-ethnic-study-of-atherosclerosis
#20
S M Iftekhar Uddin, Mohammadhassan Mirbolouk, Zeina Dardari, David I Feldman, Miguel Cainzos-Achirica, Andrew P DeFilippis, Philip Greenland, Ron Blankstein, Kevin L Billups, Martin Miner, Khurram Nasir, Michael J Blaha
Vascular erectile dysfunction (ED) and cardiovascular disease (CVD) share common risk factors including obesity, hypertension, metabolic syndrome, diabetes mellitus, and smoking. ED and CVD also have common underlying pathological mechanisms, including endothelial dysfunction, inflammation, and atherosclerosis.1 Despite these close relationships, the evidence documenting ED as an independent predictor of future CVD events is limited.We therefore leveraged the MESA study (Multi-Ethnic Study of Atherosclerosis), an ethnically diverse, community-based, multisite prospective cohort study, to examine the value of self-reported ED for predicting incident coronary heart disease (CHD) and CVD in those free of these CVD events at baseline...
June 11, 2018: Circulation
keyword
keyword
86132
1
2
Fetch more papers »
Fetching more papers... Fetching...
Read by QxMD. Sign in or create an account to discover new knowledge that matter to you.
Remove bar
Read by QxMD icon Read
×

Search Tips

Use Boolean operators: AND/OR

diabetic AND foot
diabetes OR diabetic

Exclude a word using the 'minus' sign

Virchow -triad

Use Parentheses

water AND (cup OR glass)

Add an asterisk (*) at end of a word to include word stems

Neuro* will search for Neurology, Neuroscientist, Neurological, and so on

Use quotes to search for an exact phrase

"primary prevention of cancer"
(heart or cardiac or cardio*) AND arrest -"American Heart Association"