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thallium media

Radosław Mazur, Monika Sadowska, Łucja Kowalewska, Agnieszka Abratowska, Hazem M Kalaji, Agnieszka Mostowska, Maciej Garstka, Beata Krasnodębska-Ostręga
BACKGROUND: Heavy metal exposure affect plant productivity by interfering, directly and indirectly, with photosynthetic reactions. The toxic effect of heavy metals on photosynthetic reactions has been reported in wide-ranging studies, however there is paucity of data in the literature concerning thallium (Tl) toxicity. Thallium is ubiquitous natural trace element and is considered the most toxic of heavy metals; however, some plant species, such as white mustard (Sinapis alba L.) are able to accumulate thallium at very high concentrations...
2016: BMC Plant Biology
María Teresa Luján Pino, Clarisa Marotte, Sandra Viviana Verstraeten
We have reported recently that the proliferation of PC12 cells exposed to micromolar concentrations of Tl(I) or Tl(III) has different outcomes, depending on the absence (EGF(-) cells) or the presence (EGF(+) cells) of epidermal growth factor (EGF) added to the media. In the current work, we investigated whether EGF supplementation could also modulate the extent of Tl(I)- or Tl(III)-induced cell apoptosis. Tl(I) and Tl(III) (25-100 μM) decreased cell viability in EGF(-) but not in EGF(+) cells. In EGF(-) cells, Tl(I) decreased mitochondrial potential, enhanced H2O2 generation, and activated mitochondrial-dependent apoptosis...
July 13, 2016: Archives of Toxicology
Kenji Matsumoto, Shoichi Ehara, Mikumo Sakaguchi, Kenichiro Otsuka, Takao Hasegawa, Kenei Shimada, Minoru Yoshiyama
BACKGROUND: The presence of cardiac involvement in sarcoidosis, a multisystem granulomatous disease of unknown etiology, is associated with very poor prognosis. Therefore, early detection of cardiac sarcoidosis (C-sar) is very important for effective treatment. Recently, the value of late gadolinium enhancement (LGE) on cardiac magnetic resonance (CMR), which allows visualization of even minute amounts of myocardial damage, has been emphasized in diagnosing C-sar. Although the presence of LGE has been added as a minor criterion for diagnosing C-sar in the most recent Japan Ministry of Health and Welfare (JMHW) guidelines, its clinical utility remains unknown...
June 2015: Osaka City Medical Journal
María T L Pino, Sandra V Verstraeten
The effects of thallium [Tl(I) and Tl(III)] on the PC12 cell cycle were evaluated without (EGF(-)) or with (EGF(+)) media supplementation with epidermal growth factor (EGF). The following markers of cell-cycle phases were analyzed: cyclin D1 (G1 ); E2F-1, cyclin E and cytosolic p21 (G1 →S transition); nuclear PCNA and cyclin A (S); and cyclin B1 (G2). The amount of cells in each phase and the activation of the signaling cascade triggered by EGF were also analyzed. Tl(I) and Tl(III) (5-100 μM) caused dissimilar effects on PC12 cell proliferation...
August 2015: Journal of Applied Toxicology: JAT
Christos Kokkinos, Anastasios Economou
The present work describes the trace analysis of Tl(I) in acidic medium (0.05 mol L(-1) nitric acid) by square wave anodic stripping voltammetry (SWASV) at a tin film sensor with novel configuration. This "green" electroanalytical device features on-chip metal film electrodes (a Sn-film working electrode, a Ag-film reference electrode and a Pt-film counter electrode), fabricated by sputtering the respective metals on a silicon chip. The effect of preconcentration time, preconcentration potential and SW stripping parameters on the Tl(I) detection was studied in detail...
July 2014: Talanta
Y Du, J M Links, L Becker, A F DiPaula, T Frank, K H Schuleri, A C Lardo, E C Frey
BACKGROUND: Simultaneous (201)Tl/(99m)Tc-sestamibi dual-isotope myocardial perfusion SPECT imaging can reduce imaging time and produce perfectly registered rest/stress images. However, crosstalk from (99m)Tc into (201)Tl images can significantly reduce (201)Tl image quality. We have developed a model-based compensation (MBC) method to compensate for this crosstalk. The method has previously been validated with phantom and simulation studies. In this study, we evaluated the MBC method using a canine model...
April 2014: Journal of Nuclear Cardiology: Official Publication of the American Society of Nuclear Cardiology
Katerina Bačeva, Trajče Stafilov, Robert Sajn, Claudiu Tănăselia
A systematic study was carried out to investigate air deposition and to explore the natural distribution and enrichment (contamination) with trace elements in the small area (cca. 13 km(2)) of an antimony-arsenic-thallium mineralization outcrop at an abandoned mine "Allchar." The mine is located on the northwestern part of Kožuf Mount, Republic of Macedonia. The locality of Allchar is unique in its mineral composition; besides a very intriguing mineral, lorandite, there are 45 other minerals, some of which are rare...
December 2013: Environmental Science and Pollution Research International
Brian K Crownover, Jennifer L Bepko
Risks of diagnostic imaging include cancer from radiation exposure and nephrogenic systemic fibrosis. The increase in volume of imaging between 1980 and 2006 has led to a sixfold increase in annual per capita radiation exposure. It is predicted that 2 percent of future cancers will be caused by radiation from computed tomography (CT) exposure. Gadolinium contrast media should be avoided in patients with stage 4 or 5 chronic kidney disease because of the risk of nephrogenic systemic fibrosis. Appropriate use of imaging based on guidelines for specific clinical conditions can reduce these risks...
April 1, 2013: American Family Physician
Ko Higuchi, Michinobu Nagao, Yoshio Matsuo, Takeshi Kamitani, Masato Yonezawa, Mikako Jinnouchi, Yuzo Yamasaki, Koichiro Abe, Shingo Baba, Yasushi Mukai, Taiki Higo, Kenji Sunagawa, Hiroshi Honda
PURPOSE: To investigate myocardial viability in chronic ischemic heart disease by myocardial perfusion and regional contraction analysis using 256-slice MSCT coronary angiography (CCTA). METHODS: In 30 patients with prior myocardial infarction (MI), CCTA with retrospective ECG-gating and stress-redistribution thallium-201 SPECT were performed. Using the same raw data as used for CCTA, myocardial perfusion imaging (CT-MPI) was reconstructed at four phases during the cardiac cycle...
February 2013: Japanese Journal of Radiology
Hassanatu B Mansaray, Christina Y Tang, Dragoslav Vidovic, Amber L Thompson, Simon Aldridge
The interaction of 2,6-dimesitylpyridine with Tl(I) and In(I) cations has been investigated with a view to developing tractable molecular M(I) compounds which are soluble in organic media. In stark contrast to isosteric and isoelectronic terphenyl systems, complexes featuring the [(2,6-Mes(2)py)M](+) fragment feature very weak metal-ligand interactions in the solid state, as revealed by M-N distances of the order of 2.45 Å (M = In) and 2.64 Å (M = Tl). While additional weak π interactions are observed with arene solvate molecules in these systems, the related 2:1 complex [(2,6-Mes(2)py)(2)In][BAr(f)(4)] features an In(I) center wholly encapsulated by the bulky Mes(2)py donors, and even longer In-N distances [2...
December 3, 2012: Inorganic Chemistry
Andrew Turner, Oliver Furniss
Thallium(I) has been added to cultures of the marine macroalga, Ulva lactuca, for a period of 48 h and the accumulation of the metal and its effects on the photochemical efficiency of photosystem II (PS II) measured. Thallium elicited a measurable toxic response above concentrations of 10 μg L⁻¹ in both coastal seawater (salinity 33) and estuarine water (salinity 20). The accumulation of Tl was defined by a linear relationship with aqueous Tl and accumulation factors of about 900 mL g⁻¹ in both media...
December 2012: Marine Pollution Bulletin
Siavash Nouroozi, Hassan Biglary, Behzad Haghighi
In this work, a new simple and sensitive flow injection method is developed for the determination of homocysteine with spectrofluorimetric detection technique. This method is based on the oxidation of homocysteine with Tl (III) in acidic media, producing fluorescence reagent, TlCl(3)(2-) (λ(ex) = 237 nm, λ(em) = 419 nm). The effects of chemical parameters (including pH of the solutions, the buffer, Tl (III) and potassium chloride concentrations), instrumental parameters (such as flow rate of the solutions, reaction coil length, and sample loop volume) and temperature on the fluorescence intensity as an analytical signal are studied and optimized...
January 2012: Journal of Fluorescence
Matthias Regenfus, Christian Schlundt, Johannes von Erffa, Michaela Schmidt, Udo Reulbach, Torsten Kuwert, Werner G Daniel, Michael Schmid
Delayed contrast-enhanced cardiovascular magnetic resonance (DE-CMR) allows assessment of reversibility of myocardial dysfunction. Comparative data to other modalities is scarce. Purpose of this study was to compare DE-CMR and (201)Thallium single photon emission computed tomography (SPECT) for prediction of reversible left ventricular (LV) dysfunction in patients with chronic ischaemic heart disease. Fifty-four patients with LV dysfunction (mean ejection fraction (EF) 35 ± 8%) scheduled to undergo myocardial revascularization underwent DE-CMR and SPECT...
August 2012: International Journal of Cardiovascular Imaging
Sergey M Korotkov, Nils-Erik L Saris
The Tl(+)-induced opening of the MPTP in Ca(2+)-loaded rat liver mitochondria energized by respiration on the substrates succinate or glutamate plus malate was recorded as increased swelling and dissipation of mitochondrial membrane potential as well as decreased state 4, or state 3, or 2,4-dinitrophenol-stimulated respiration. These effects of Tl(+) increased in nitrate media containing monovalent cations in the order of Li(+) < NH (4) (+) ≤ Na(+) < K(+). They were potentiated by inorganic phosphate and diminished by the MPTP inhibitors (ADP, CsA, Mg(2+), Li(+), rotenone, EGTA, and ruthenium red) both individually and more potently in their combinations...
April 2011: Journal of Bioenergetics and Biomembranes
Mi-Hyun Hwang, Dereje Damte, Min-Hee Cho, Young-Hoan Kim, Seung-Chun Park
Composition of culture medium for mass production of Mycoplasma hyopneumoniae was optimized using a response surface methodology (RSM). Initially, the influence of glucose, thallium acetate, fresh yeast extract, horse serum, and porcine serum on the production of mycoplasmal protein was assessed using a 'one factor at a time' technique. Next, factors with a significant effect, including fresh yeast extract, and horse and porcine sera, were selected for further optimization using a central composite design (CCD) of RSM...
December 2010: Journal of Veterinary Science
A O Sherstobitov, A V Lapin, V V Glazunov, A A Nikiforov
Mechanisms of transport of monovalent thallium across the membrane of oocyte of the lamprey Lampetra fluviatilis were studied by using 204Tl. Transport of Tl+ in lamprey oocytes has been shown to be realized by at least two pathways: through Na/K-pump and by the mechanism of Na,K,Cl-cotransport. In the standard Ringer solution (mM): 4 KCl, 140 NaCl, 0.5 CaCl2, 5 glucose, 10 Tris-HCl--in the presence of oubain, the coefficient of the 204Tl stationary distribution (cell/medium) was within the range of 2.3-2.5, while the time necessary to reach its 50 % value amounted to 40-5 min at 20 degrees C...
May 2010: Zhurnal Evoliutsionnoĭ Biokhimii i Fiziologii
A L Iudin, P V Vasil'ev, Iu A Pokrovskiĭ
Currently employed methods of tomographic diagnostics for the evaluation of effectiveness of the treatment of laryngeal and laryngopharyngeal cancer are described. The authors underscore that increasingly more attention tends to be given to magnetoresonance imaging (MRI) and especially X-ray computer tomography (CT) due to their wide application and high informative value whereas nuclear medicine techniques, such as single-photon emission CT using thallium-200, 11C-methionine and (18)F-positron emission tomography, are considered to be less important despite their great diagnostic potentialities...
2010: Vestnik Otorinolaringologii
Satoshi Okayama, Hiroyuki Kawata, Ji Hee Sung, Sadanori Okada, Taku Nishida, Kenji Onoue, Tsunenari Soeda, Shiro Uemura, Yoshihiko Saito
Apical hypertrophic cardiomyopathy (HCM) is an uncommon variant of HCM characterized by hypertrophy located in the left ventricular apex that occurs at a rate of about 30% in the Japanese population. Although the prognosis of most patients with apical HCM is relatively benign, it can be poor if apical left ventricular aneurysms develop. However, the mechanism of aneurysmal formation is unclear. We describe two patients with apical HCM and dissimilar findings in 201Thallous chloride ((201)TlCl) and (123)I-betamethyl-p-iodophenyl-pentadecanoic acid ((123)I-BMIPP) dual single-photon emission computed tomography (dual-SPECT), but no myocardial fibrosis on contrast-enhanced magnetic resonance images (MRI)...
2010: Cardiology Journal
Shih-Tai Chang, Chi-Ming Chu, Jen-Te Hsu, Ju-Feng Hsiao, Chang-Min Chung, Cheng Ho, Yun-Shing Peng, Pao-Yin Chen, Jia-Jen Shee
INTRODUCTION: There is growing evidence of a link between erectile dysfunction (ED) and coronary artery disease (CAD). AIMS: The purpose of this study was to explore the independent determinants of CAD in ED outpatients. METHODS: This study enrolled 243 patients, ranging in age from 21 to 81 years old, suffering from ED as diagnosed by the International Index of Erectile Function (IIEF) scores. All patients underwent exercise stress tests or thallium-201 single-photon emission computed tomography perfusion imagings...
April 2010: Journal of Sexual Medicine
Zekiye Hasbek, Bulent Turgut, Taner Erselcan, Kenan Yalta, Izzet Tandogan, Gurkan Ozer, Umit Ozdemir, Nergiz Hacer Turgut
AIM: The aim of this study was to evaluate the myocardial viability in nondiabetic patients with chronic coronary artery disease (CCAD) or past myocardial infarction (MI), using thallium-201 infusion myocardial perfusion single-photon emission computed tomography (MPSPECT) imaging after oral glucose application (Glu+Tl-infusion). MATERIALS AND METHODS: In this study, 33 nondiabetic patients (three female, 30 male, mean age: 55.24+/-11 years, range: 33-77 years) with MI history or known CCAD were included...
October 2009: Nuclear Medicine Communications
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