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cardiac contrast mediums

Marc-Alexander Ohlow, Ahmed Farah, Stefan Richter, Mohamad El-Garhy, Hubertus von Korn, Bernward Lauer
BACKGROUND: In a number of coronary bifurcation lesions, both the main vessel and the side branch (SB) need stent coverage. OBJECTIVES: To analyze the procedural performance and the impact on radiation times (RT) and contrast medium consumption (CMC) of the Axxess™ stent system (Biosensors, Switzerland) treating de novo bifurcation lesions (DBL). METHODS: One hundred and ten consecutive prospectively enrolled cases (Axxess Group) and 110 age, sex, and lesion location matched controls undergoing mandatory (Group A, n = 56) or provisional (Group B, n = 54) SB intervention were analyzed...
September 21, 2016: Catheterization and Cardiovascular Interventions
Markus-Johann Dechant, Natascha van der Werf-Grohmann, Elena Neumann, Ute Spiekerkoetter, Brigitte Stiller, Jochen Grohmann
BACKGROUND: Cardiac catheterisation requiring the use of contrast medium is increasingly utilised in infants with congenital heart disease. Thyroid function in infants is potentially vulnerable to relatively high doses of iodine. METHODS: Single-centre prospective study of 21 patients (10 neonates, 11 infants) exposed to iodine during cardiac catheterisation. Median age was 30days (1-180), median body weight 3.3kg (1.6-7.0). Serum-levels of thyroid-stimulating hormone (TSH), free triiodothyronine (fT3) and free thyroxine (fT4) were measured at baseline before, and at three different times points after intervention...
November 15, 2016: International Journal of Cardiology
Lloyd M Felmly, Carlo N De Cecco, U Joseph Schoepf, Akos Varga-Szemes, Stefanie Mangold, Andrew D McQuiston, Sheldon E Litwin, Richard R Bayer, Thomas J Vogl, Julian L Wichmann
PURPOSE: To investigate feasibility, image quality and safety of low-tube-voltage, low-contrast-volume comprehensive cardiac and aortoiliac CT angiography (CTA) for planning transcatheter aortic valve replacement (TAVR). MATERIALS AND METHODS: Forty consecutive TAVR candidates prospectively underwent combined CTA of the aortic root and vascular access route (270 mgI/ml iodixanol). Patients were assigned to group A (second-generation dual-source CT [DSCT], 100 kV, 60 ml contrast, 4...
August 23, 2016: European Radiology
Michael Bietenbeck, Anca Florian, Cornelius Faber, Udo Sechtem, Ali Yilmaz
Magnetic resonance imaging (MRI) allows for an accurate assessment of both functional and structural cardiac parameters, and thereby appropriate diagnosis and validation of cardiovascular diseases. The diagnostic yield of cardiovascular MRI examinations is often increased by the use of contrast agents that are almost exclusively based on gadolinium compounds. Another clinically approved contrast medium is composed of superparamagnetic iron oxide nanoparticles (IONs). These particles may expand the field of contrast-enhanced cardiovascular MRI as recently shown in clinical studies focusing on acute myocardial infarction (AMI) and atherosclerosis...
2016: International Journal of Nanomedicine
Chetan P Huded, Quentin R Youmans, Ranya N Sweis, Mark J Ricciardi, James D Flaherty
OBJECTIVES: We studied the impact of operator experience on trans-radial (TR) cardiac catheterization performance in contemporary practice. BACKGROUND: TR cardiac catheterization offers advantages over trans-femoral (TF) cardiac catheterization, but the TR approach has been slowly adopted in the United States. METHODS: We reviewed all cases of attempted TR cardiac catheterization at a single tertiary care medical center from May 2008 until April 2015...
July 29, 2016: Catheterization and Cardiovascular Interventions
Emanuela de Cillis, Annamaria Dachille, Francesco Giardinelli, Tommaso Acquaviva, Alessandro Santo Bortone
INTRODUCTION: Transcatheter aortic valve implantation (TAVI) technique represents a real revolution in the field of interventional cardiology and medicine, in particular for the treatment of severe aortic valve stenosis in elderly patients or in patients when the periprocedural risk for the traditional surgical option is considered too high, as an alternative to the traditional aortic valve replacement. Although experience on the valves of the last generation is still limited in terms of time, the data currently available are definitely moving in the direction of a minimum hospital mortality (1%) as well as a drastic reduction in the incidence of complications when compared to the devices of the previous generation...
July 29, 2016: Surgical Technology International
Michele Brunelli, Markus Frommhold, Dieter Back, Marco Mierzwa, Bernard Lauer, J Christoph Geller
A 70-year-old woman with persistent atrial fibrillation underwent pulmonary vein isolation and linear ablation with a contact sensor catheter. During cavotricuspid isthmus ablation, a steam pop resulted in cardiac tamponade, and the patient developed severe hypotension despite successful pericardial puncture and minimal residual pericardial effusion. Right coronary artery angiography revealed extravasal contrast medium accumulation posterior of the Crux Cordis. Emergent cardiac surgery confirmed isolated disruption of the artery in the absence of additional heart perforation...
July 2016: Pacing and Clinical Electrophysiology: PACE
Fu Tsai Chiang, Kuang Hua Chu, Ching Yuan Chen, Chien Yi Chen, Lung Kwang Pan
OBJECTIVE: Taguchi's analysis was adopted to optimize the various factors referring to cardiac angiographic examination used to delineating ductus arteriosus in pediatric patients. SUBJECTS AND METHODS: Thirty-six pediatric patients, 9 male and 27 female, mean age of 6.5±4.7yrs, range 0.6 to 16.6 years were included in the study from January 2004 to April 2005. All patients had patent ductus arteriosus (PDA). Taguchi's L9 orthogonal array was used to generate nine different designs of angiographic levels...
May 2016: Hellenic Journal of Nuclear Medicine
Haruhiko Machida, Rika Fukui, Jianbo Gao, Isao Tanaka, Yun Shen, Shigeru Suzuki, Takuya Ishikawa, Eiko Ueno
OBJECTIVES: The aim of this study was to assess the effect of monochromatic imaging at various energy levels in combination with a motion correction algorithm (MCA) in single-source dual-energy coronary computed tomography angiography (CCTA) with fast switching of tube voltage on the reduction of coronary motion artifacts (CMA) in a phantom setting. MATERIALS AND METHODS: Using this dual-energy computed tomography technique with a phantom comprising models of coronary vessels filled with contrast medium and pulsating at constant heart rates of 60 to 100 beats per minute, we reconstructed monochromatic images of CCTA obtained at 50 to 90 keV with and without use of MCA...
August 2016: Investigative Radiology
Hirofumi Arai, Takamichi Miyamoto, Nobuhiro Hara, Tohru Obayashi
An 89-year-old woman with severe aortic valve stenosis and bradycardia presented with circulatory shock due to cardiac tamponade. We performed pericardiocentesis, and then diagnosed right ventricular perforation by echocardiography with microcavitation contrast medium just before inserting a drainage tube. We then inserted the drainage tube in the appropriate position and withdrew blood-filled fluid. The patient was haemodynamically stabilised, but haemorrhage from the perforation site continued for a few days...
2016: BMJ Case Reports
Sadi Loai, Inga Haedicke, Zahra Mirzaei, Craig A Simmons, Xiao-An Zhang, Hai-Ling Margaret Cheng
PURPOSE: To investigate the feasibility of high-sensitivity cellular MRI of embryonic stem (ES) cells using a novel cell permeable and cell retentive T1 contrast agent. MATERIALS AND METHODS: Mouse ES cells were labeled with a novel manganese porphyrin contrast agent, MnAMP, at 0.1 mM over 2 to 24 h and retained in contrast-free medium for up to 24 h postlabeling. MRI was performed on a 3 Tesla clinical scanner; T1 and T2 relaxation times were measured. Quantification of manganese content was performed using atomic absorption spectroscopy...
May 17, 2016: Journal of Magnetic Resonance Imaging: JMRI
Caroline E Gargett, Shanti Gurung
No abstract text is available yet for this article.
June 2016: Biology of Reproduction
Todd C Pulerwitz, Omar K Khalique, Tamim N Nazif, Anna Rozenshtein, Gregory D N Pearson, Rebecca T Hahn, Torsten P Vahl, Susheel K Kodali, Isaac George, Martin B Leon, Belinda D'Souza, Ming Jack Po, Andrew J Einstein
BACKGROUND: Transcatheter aortic valve replacement (TAVR) is a lifesaving procedure for many patients high risk for surgical aortic valve replacement. The prevalence of chronic kidney disease (CKD) is high in this population, and thus a very low contrast volume (VLCV) computed tomography angiography (CTA) protocol providing comprehensive cardiac and vascular imaging would be valuable. METHODS: 52 patients with severe, symptomatic aortic valve disease, undergoing pre-TAVR CTA assessment from 2013-4 at Columbia University Medical Center were studied, including all 26 patients with CKD (eGFR<30 mL/min) who underwent a novel VLCV protocol (20 mL of iohexol at 2...
July 2016: Journal of Cardiovascular Computed Tomography
Adrien Flahault, Denis Trystram, Marie Fouchard, Bertrand Knebelmann, François Nataf, Dominique Joly
BACKGROUND: Despite a high prevalence of intracranial aneurysm (ICA) in autosomal dominant polycystic kidney disease (ADPKD), rupture events are rare. The current recommendations for ICA screening are based on expert opinions and studies with low levels of evidence. OBJECTIVES: The aim of our study was to describe the attitudes of practicing nephrologists in Europe towards screening for ICA using magnetic resonance angiography (MRA). METHODS: We conducted a web-based survey among 1315 European French-speaking nephrologists and nephrology residents...
2016: PloS One
R J Everett, C G Stirrat, S I R Semple, D E Newby, M R Dweck, S Mirsadraee
Myocardial fibrosis can arise from a range of pathological processes and its presence correlates with adverse clinical outcomes. Cardiac magnetic resonance (CMR) can provide a non-invasive assessment of cardiac structure, function, and tissue characteristics, which includes late gadolinium enhancement (LGE) techniques to identify focal irreversible replacement fibrosis with a high degree of accuracy and reproducibility. Importantly the presence of LGE is consistently associated with adverse outcomes in a range of common cardiac conditions; however, LGE techniques are qualitative and unable to detect diffuse myocardial fibrosis, which is an earlier form of fibrosis preceding replacement fibrosis that may be reversible...
August 2016: Clinical Radiology
V Spagnoli, L Azzalini, V X Tadros, F Picard, H Q Ly
Contrast-induced nephropathy (CIN) is common in hospitalized patients. Its occurrence is associated with an increased hospitalization stay and cost, morbidity and mortality. Thus, preventives strategies remain a major issue. Patients that are referred for cardiac catheterization are among the most vulnerable to develop CIN due to their comorbidities. Moreover, in some cases, such preventives measures cannot be introduced due to emergent clinical settings. After a summary regarding the properties of iodinated contrast medium, the aim of this work was to review the definition, pathophysiology, diagnosis and preventive strategies related to CIN...
April 2016: Annales de Cardiologie et D'angéiologie
Yanming Fan, Qingmin Wei, Junna Cai, Yongtang Shi, Youliang Zhang, Limei Yao, Xiaogang Wang, Shupo Lin, Yilin Li, Jing Lv, Bin Zhou, Ruijuan Du
This study aims to investigate the preventive effect of oral nicorandil on contrast-induced nephropathy (CIN) in patients with renal insufficiency undergoing elective cardiac catheterization. A total of 240 patients with an estimated glomerular filtration rate (eGFR) of 60 mL/min or less, who were undergoing elective cardiac catheterization, were randomly assigned to nicorandil group (n = 120, 10 mg nicorandil, three times daily from 2 days before to 3 days after procedure) or control group (n = 120, matching placebo as the same method)...
February 13, 2016: Heart and Vessels
Kun Wang, Chong-Yang Duan, Jun Wu, Yong Liu, Wei-Jie Bei, Ji-Yan Chen, Peng Cheng He, Yuan-Hui Liu, Ning Tan
BACKGROUND: Neutrophil gelatinase-associated lipocalin (NGAL) accumulates in cortical tubules in acute kidney injury (AKI) patients, with its levels associated with serum creatinine. However, the predictive value of NGAL level for contrast-induced acute kidney injury (CI-AKI) remains unclear. METHODS: A total of 1520 patients from 14 relevant studies retrieved from PUBMED, MEDLINE, EMBASE, Web of Science,, Cochrane Library, and Google Scholar from the inception to November 2014 and 15 data sets were included...
August 2016: Canadian Journal of Cardiology
Alberto Polimeni, Francesco Passafaro, Salvatore De Rosa, Sabato Sorrentino, Daniele Torella, Carmen Spaccarotella, Annalisa Mongiardo, Ciro Indolfi
The radial artery has been increasingly used for its favorable safety profile. However, no conclusive data are available on the optimal sheath size. In particular, it is seemingly difficult to weight both advantages and disadvantages of narrower versus larger sheaths size. Despite several studies were performed to compare the use of 6-Fr to the smaller 5-Fr sheaths, these were mostly small, single center-studies, yielding various results.We performed a comprehensive meta-analysis of all available studies comparing the use of 5-Fr versus 6-Fr sheaths in coronary procedures through the TRA...
December 2015: Medicine (Baltimore)
Jessica E Middlemiss, Karen L Miles, Barry J McDonnell, Yasmin, Kaisa M Maki-Petaja, John R Cockcroft, Ian B Wilkinson, Carmel M McEniery
OBJECTIVES: The positive association between adiposity and hypertension is well recognized. However, not all overweight individuals have elevated blood pressure (BP). Moreover, different factors may be associated with high BP in normal-weight versus overweight individuals. The aim of the current study was to examine the influence of adiposity on the relationship between SBP and underlying haemodynamic mechanisms in young adults. METHOD: Data from 2502 patients were available from the Enigma study...
February 2016: Journal of Hypertension
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