keyword
https://read.qxmd.com/read/38700365/bronchiectasis-in-t%C3%A3-rkiye-data-from-a-multicenter-registry-turkish-adult-bronchiectasis-database
#1
MULTICENTER STUDY
Ebru Çakır Edis, Aykut Çilli, Deniz Kızılırmak, Ayşın Şakar Coşkun, Nurcan Güler, Sedat Çiçek, Can Sevinç, Meltem Çoban Ağca, İnci Gülmez, Benan Çağlayan, Mehmet Kabak, Elif Yelda Özgün Niksarlıoğlu, Nurdan Köktürk, Abdullah Sayıner
BACKGROUND: Bronchiectasis is a chronic lung disease characterized by permanent bronchial wall dilatation. Although it has been known as an orphan disease, it has recently gained attention because of registry-based studies and drug research. AIMS: We aimed to use a multicenter database to analyze and compare data regarding the etiology, associated comorbidities, microbiological characteristics, and preventive strategies of bronchiectasis in Türkiye to those of other countries...
May 3, 2024: Balkan Medical Journal
https://read.qxmd.com/read/38699695/the-relationship-between-lactate-dehydrogenase-and-apolipoprotein-a1-levels-in-patients-with-severe-pneumonia
#2
JOURNAL ARTICLE
Jiang Wang, Ronghua Wang, Ying Zhou, Yao Ma, Chunyan Xiong
BACKGROUND: To investigate the relationship between lactate dehydrogenase and apolipoprotein A1 levels and the condition and prognosis of patients with severe pneumonia. METHODS: Data was collected from 204 patients with severe pneumonia who were hospitalized from January 1, 2019 to December 1, 2021 in Zhaotong First People's Hospital (respiratory intensive care unit (RICU)), and divided into survival group (160 patients) and death group (44 patients) according to their hospitalization outcome...
April 23, 2024: Journal of Medical Biochemistry
https://read.qxmd.com/read/38699425/heatstroke-a-multicenter-study-in-southwestern-china
#3
MULTICENTER STUDY
Lvyuan Shi, Bo Wang, Qin Wu, Jing Yang, Lietao Wang, Dingyuan Wan, Yucong Wang, Zhongxue Feng, Wei Zhang, Li Li, Wenhu Wang, Jun Chen, Xiaohua Ai, Jianwei Zheng, Zhongwei Zhang, Min He
BACKGROUND: An increase in Heatstroke cases occurred in southwest China in 2022 due to factors like global warming, abnormal temperature rise, insufficient power supply, and other contributing factors. This resulted in a notable rise in Heatstroke patients experiencing varying degrees of organ dysfunction. This descriptive study aims to analyze the epidemiology and clinical outcomes of Heatstroke patients in the ICU, providing support for standardized diagnosis and treatment, ultimately enhancing the prognosis of Heatstroke...
2024: Frontiers in Public Health
https://read.qxmd.com/read/38698792/improving-patient-outcomes-following-vital-sign-monitoring-protocol-failure-a-retrospective-cohort-study
#4
JOURNAL ARTICLE
H E Sebastian Seitz-Rasmussen, Morten Føns-Sønderskov, Anne-Marie Kodal, Morten H Bestle
BACKGROUND AND AIMS: Vital sign monitoring needs to be timely and correct to recognize deteriorating patients early and trigger the relevant clinical response. The aim of this study is to retrospectively evaluate compliance specifically toward the regional vital sign monitoring protocol the so called early warning score protocol (EWS-protocol) 72 h before a medical emergency team response (MET-response) and thereby illuminate whether poor compliance translates into a worse patient outcome...
May 2024: Health Science Reports
https://read.qxmd.com/read/38694580/analysis-on-short-term-outcomes-for-cerebral-protection-treatment-in-post-severe-traumatic-brain-injury-patients-a-single-neurosurgical-centre-study
#5
JOURNAL ARTICLE
Ahmad Fikri Muhammad Mustafa, Laila Ab Mukmin, Mohd Zulfakar Mazlan, Abdul Rahman Izaini Ghani, Wan Mohd Nazaruddin Wan Hassan, Mohamad Hasyizan Hassan
BACKGROUND: Severe traumatic brain injury (TBI) is a leading cause of disability worldwide and cerebral protection (CP) management might determine the outcome of the patient. CP in severe TBI is to protect the brain from further insults, optimise cerebral metabolism and prevent secondary brain injury. This study aimed to analyse the short-term Glasgow Outcome Scale (GOS) at the intensive care unit (ICU) discharge and a month after ICU discharge of patients post CP and factors associated with the favourable outcome...
April 2024: Malaysian Journal of Medical Sciences: MJMS
https://read.qxmd.com/read/38694135/predictors-of-intensive-care-unit-admissions-in-patients-presenting-with-coronavirus-disease-2019
#6
JOURNAL ARTICLE
Lahib Douda, Heraa Hasnat, Jennifer Schwank, Sarien Nassar, Nancy M Jackson, Jeffrey C Flynn, Joseph Gardiner, Dawn P Misra, Abdulghani Sankari
Background  Increased mortality rates among coronavirus disease 2019 (COVID-19) positive patients admitted to intensive care units (ICUs) highlight a compelling need to establish predictive criteria for ICU admissions. The aim of our study was to identify criteria for recognizing patients with COVID-19 at elevated risk for ICU admission. Methods  We identified patients who tested positive for COVID-19 and were hospitalized between March and May 2020. Patients' data were manually abstracted through review of electronic medical records...
January 2024: Avicenna Journal of Medicine
https://read.qxmd.com/read/38692709/risk-factors-for-asthma-related-hospital-and-intensive-care-admissions-in-children-adolescents-and-adults-a-cohort-study-using-primary-and-secondary-care-data
#7
JOURNAL ARTICLE
Nikita Simms-Williams, Prasad Nagakumar, Rasiah Thayakaran, Nicola J Adderley, Richard Hotham, Adel H Mansur, Krishnarajah Nirantharakumar, Shamil Haroon
BACKGROUND: Asthma remains a common cause of hospital admissions across the life course. We estimated the contribution of key risk factors to asthma-related hospital and intensive care unit (ICU) admissions in children, adolescents and adults. METHODS: This was a UK-based cohort study using linked primary care (Clinical Practice Research Datalink Aurum) and secondary care (Hospital Episode Statistics Admitted Patient Care) data. Patients were eligible if they were aged 5 years and older and had been diagnosed with asthma...
May 1, 2024: BMJ Open Respiratory Research
https://read.qxmd.com/read/38691362/covid-19-hospitalization-in-hawai-i-and-patterns-of-insurance-coverage-race-and-ethnicity-and-vaccination
#8
JOURNAL ARTICLE
Brock M Santi, Philip A Verhoef
IMPORTANCE: The people of Hawai'i have both high rates of health insurance and high levels of racial and ethnic diversity, but the degree to which insurance status and race and ethnicity contribute to health outcomes in COVID-19 remains unknown. OBJECTIVE: To evaluate the associations of insurance coverage, race and ethnicity (using disaggregated race and ethnicity data), and vaccination with outcomes for COVID-19 hospitalization. DESIGN, SETTING, AND PARTICIPANTS: This retrospective cohort study included hospitalized patients at a tertiary care medical center between March 2020 and March 2022...
May 1, 2024: JAMA Network Open
https://read.qxmd.com/read/38691014/comparison-of-mannitol-and-hypertonic-saline-solution-for-the-treatment-of-suspected-brain-herniation-during-prehospital-management-of-traumatic-brain-injury-patients
#9
JOURNAL ARTICLE
Anais Codorniu, Emilie Charbit, Marie Werner, Arthur James, Jean-Luc Hanouz, Daniel Jost, Armelle Severin, Elodie Lang, Julien Pottecher, Malory Favreau, Emmanuel Weiss, Paer Selim Abback, Jean-Denis Moyer
BACKGROUND AND IMPORTANCE: Occurrence of mydriasis during the prehospital management of traumatic brain injury (TBI) may suggest severe intracranial hypertension (ICH) subsequent to brain herniation. The initiation of hyperosmolar therapy to reduce ICH and brain herniation is recommended. Whether mannitol or hypertonic saline solution (HSS) should be preferred is unknown. OBJECTIVES: The objective of this study is to assess whether HSS, compared with mannitol, is associated with improved survival in adult trauma patients with TBI and mydriasis...
April 30, 2024: European Journal of Emergency Medicine: Official Journal of the European Society for Emergency Medicine
https://read.qxmd.com/read/38689750/development-and-validation-of-a-nomogram-for-predicting-in-hospital-mortality-of-intensive-care-unit-patients-with-liver-cirrhosis
#10
JOURNAL ARTICLE
Xiao-Wei Tang, Wen-Sen Ren, Shu Huang, Kang Zou, Huan Xu, Xiao-Min Shi, Wei Zhang, Lei Shi, Mu-Han Lü
BACKGROUND: Liver cirrhosis patients admitted to intensive care unit (ICU) have a high mortality rate. AIM: To establish and validate a nomogram for predicting in-hospital mortality of ICU patients with liver cirrhosis. METHODS: We extracted demographic, etiological, vital sign, laboratory test, comorbidity, complication, treatment, and severity score data of liver cirrhosis patients from the Medical Information Mart for Intensive Care IV (MIMIC-IV) and electronic ICU (eICU) collaborative research database (eICU-CRD)...
April 27, 2024: World Journal of Hepatology
https://read.qxmd.com/read/38689477/association-of-obesity-and-the-clinical-course-of-hospitalised-covid-19-survivors
#11
JOURNAL ARTICLE
Ali Emamjomeh, Noushin Mohammadifard, Mehdi Abbasi, Mozhde Askari, Marzieh Taheri, Sahel Javanbakht, Mahshid Ahmadian, Maedeh Sayyah, Shirin Mahmoudi, Kamal Heidari, Nizal Sarrafzadegan
Obesity is a risk factor for chronic inflammation and severe pulmonary infections. This study aimed to assess the association between obesity and the clinical courses of hospitalised COVID-19 survivors. This cross-sectional study used the Isfahan COVID Cohort (ICC) baseline data. The ICC is an ongoing, 5-year prospective, longitudinal cohort study conducted on hospitalised COVID-19 survivors in affiliated hospitals of the Medical University of Isfahan (MUI), Iran. Patients aged 19 and over throughout Isfahan County were recruited using a consecutive sampling method 1 month after discharge...
April 30, 2024: Clinical Obesity
https://read.qxmd.com/read/38689361/relationship-between-lactate-to-albumin-ratio-and-28-day-mortality-in-patients-with-exacerbation-of-chronic-obstructive-pulmonary-disease-admitted-to-the-intensive-care-unit
#12
JOURNAL ARTICLE
Jun Xie, Hui Liu, Qian He, Chong Li
AIM: To explore the predictive value of lactate-to-albumin ratio (LAR) on 28-day mortality in patients with exacerbation of chronic obstructive pulmonary disease (AECOPD) admitted to the Intensive Care Unit (ICU). METHODS: According to ICD-9 and ICD-10 diagnosis codes, patients diagnosed with AECOPD in the Medical Information Mart for Intensive Care IV (v.2.2) database were selected. The primary endpoint was 28-day mortality after ICU admission. We used receiver operating characteristic (ROC) curve, Kaplan-Meier (K-M) survival curve, logistic regression analyses and subgroup analysis to assess predictive power of LAR...
April 30, 2024: European Journal of Medical Research
https://read.qxmd.com/read/38689359/association-between-the-neutrophil-to-lymphocyte-ratio-and-in-hospital-mortality-in-patients-with-chronic-kidney-disease-and-coronary-artery-disease-in-the-intensive-care-unit
#13
JOURNAL ARTICLE
Jingjing Luo, Yufan Zhou, Yu Song, Dashuai Wang, Meihong Li, Xinling Du, Jihong Kang, Ping Ye, Jiahong Xia
BACKGROUND: The objective of this study was to investigate the correlation between neutrophil-to-lymphocyte ratios (NLR) and the risk of in-hospital death in patients admitted to the intensive care unit (ICU) with both chronic kidney disease (CKD) and coronary artery disease (CAD). METHODS: Data from the MIMIC-IV database, which includes a vast collection of more than 50,000 ICU admissions occurring between 2008 and 2019, was utilized in the study and eICU-CRD was conducted for external verification...
April 30, 2024: European Journal of Medical Research
https://read.qxmd.com/read/38688808/prescription-of-potentially-inappropriate-medications-after-an-intensive-care-unit-stay-for-acute-respiratory-failure
#14
JOURNAL ARTICLE
Somnath Bose, Danielle Groat, Joanna L Stollings, Patrick Barney, Victor D Dinglas, Valerie M Goodspeed, Harris Carmichael, Mustafa Mir-Kasimov, James C Jackson, Dale M Needham, Samuel M Brown, Carla M Sevin
BACKGROUND: Among survivors of critical illness, prescription of potentially inappropriate medications (PIM) at hospital discharge is thought to be an important, modifiable patient safety concern. To date, there are little empirical data evaluating this issue. RESEARCH QUESTION: The objective of this study was to determine the frequency of PIM prescribed to survivors of acute respiratory failure (ARF) at hospital discharge and explore their association with readmissions or death within 90 days of hospital discharge...
April 29, 2024: Australian Critical Care: Official Journal of the Confederation of Australian Critical Care Nurses
https://read.qxmd.com/read/38686375/association-between-serum-creatinine-to-albumin-ratio-and-short-and-long-term-all-cause-mortality-in-patients-with-acute-pancreatitis-admitted-to-the-intensive-care-unit-a-retrospective-analysis-based-on-the-mimic-iv-database
#15
JOURNAL ARTICLE
Jianjun Wang, Han Li, Huiwen Luo, Ruizi Shi, Sirui Chen, Junchao Hu, Hua Luo, Pei Yang, Xianfu Cai, Yaodong Wang, Xintao Zeng, Decai Wang
BACKGROUND: Serum creatinine (Cr) and albumin (Alb) are important predictors of mortality in individuals with various diseases, including acute pancreatitis (AP). However, most previous studies have only examined the relationship between single Cr or Alb levels and the prognosis of patients with AP. To our knowledge, the association between short- and long-term all-cause mortality in patients with AP and the blood creatinine to albumin ratio (CAR) has not been investigated. Therefore, this study aimed to evaluate the short- and long-term relationships between CAR and all-cause mortality in patients with AP...
2024: Frontiers in Immunology
https://read.qxmd.com/read/38685839/comparing-the-emergency-care-of-iranian-and-afghan-patients-during-the-covid-19-pandemic
#16
COMPARATIVE STUDY
Milad Ahmadi Gohari, Maryam Chegeni, Mohammad Hossein Mehrolhassani, Ali Akbar Haghdoost, Moghaddameh Mirzaee
BACKGROUND: This study investigated the quality of inpatient care provided to Afghan immigrants in Iran during the COVID-19 pandemic (February 2019 to March 2021). For this purpose, the services received by Afghan immigrants were compared with those received by Iranian citizens. METHODS: Two emergency services (traumas with 8080 victims and 8,686 patients hospitalized with severe COVID-19 infection) were taken into consideration. The records of all patients, including the Afghan immigrants, in two referral hospitals in Kerman were reviewed, and the main variables were the length of hospitalization (LoH), intensive care unit (ICU) admission rate, and death rate...
March 1, 2024: Archives of Iranian Medicine
https://read.qxmd.com/read/38683031/cognitive-impairment-following-sedative-overdose
#17
JOURNAL ARTICLE
Patrick T Stewart, Md Bayzidur Rahman, Angela L Chiew, Matt Fitzpatrick, Nicholas J Osborne, Betty S Chan
INTRODUCTION: Patients with sedative overdose may have residual cognitive impairment at the time they are deemed medically cleared for discharge. Impairment could affect the performance of high-risk activities, including driving. The Trail Making Test is an alpha-numeric assessment that can be performed at the bedside to assess cognitive function. We examined whether there were differences in cognitive function when medically cleared between patients that overdosed on sedative and non-sedative drugs...
March 2024: Clinical Toxicology
https://read.qxmd.com/read/38681793/prediction-of-th17-treg-cell-balance-on-length-of-stay-in-intensive-care-units-of-patients-with-sepsis
#18
JOURNAL ARTICLE
Yu Wu, Guosheng Wu, Minyu Li, Yongqing Chang, Miao Yu, Yan Meng, Xiaojian Wan
BACKGROUND: Prolonged length of stay (LOS) of sepsis can drain a hospital's material and human resources. This study investigated the correlations between T helper type 17 (Th17) and regulatory T (Treg) balance with LOS in sepsis. METHODS: A prospective clinical observational study was designed in Changhai Hospital affiliated to Naval Medical University in Shanghai, China, from January to October 2020. The patients diagnosed with sepsis and who met the inclusion and exclusion criteria were recruited and whether the levels of cytokines, procalcitonin, subtypes, and biomarkers of T cells in the peripheral blood were detected...
April 2024: J Intensive Med
https://read.qxmd.com/read/38680729/family-satisfaction-with-care-provided-in-intensive-care-unit-a-multi-center-cross-sectional-study
#19
JOURNAL ARTICLE
Temesgen Misganaw Liyew, Abraham Tarekegn Mersha, Belete Muluadam Admassie, Nurhusen Riskey Arefayne
BACKGROUND: Healthcare provided in medical facilities should prioritize the needs of families, as it enhances the quality of care for the patients. Family satisfaction gauges how effectively healthcare professionals address the perceived needs and expectations of family members. Numerous factors, including information dissemination, communication, family dynamics, patient characteristics, hospital facilities, and the caregiving process, serve as predictors of family satisfaction. Thus, this study seeks to evaluate the satisfaction of families with the care received by patients admitted to the intensive care unit...
2024: Patient related Outcome Measures
https://read.qxmd.com/read/38680712/clinical-characteristics-and-outcomes-in-hospitalized-patients-with-covid-19-and-cancer-history-a-multicenter-cross-sectional-study-in-southwestern-iran
#20
JOURNAL ARTICLE
Javad Zarei, Abbas Sheikhtaheri, Mehrnaz Ahmadi, Maria Cheraghi, Abdolhassan Talaiezadeh, Adeleh Khazami
Background: Cancer patients are more exposed to opportunistic infections, such as COVID-19, due to their poor health status. This study aimed to identify the clinical characteristics of cancer and non-cancer patients with COVID-19 that may lead to death, intubation, and ICU admission. Materials and Methods: A Multicenter Cross-Sectional study was conducted on confirmed COVID-19 adult patients with and without a history of cancer from March 2019 to March 2021. Demographic and clinical features, ICU admission, intubation, and discharge status have been extracted from patients' medical records...
January 1, 2024: International Journal of Hematology-oncology and Stem Cell Research
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