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Auricular cartilage

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https://www.readbyqxmd.com/read/28063220/biological-roles-of-glial-fibrillary-acidic-protein-as-a-biomarker-in-cartilage-regenerative-medicine
#1
Sanshiro Kanazawa, Satoru Nishizawa, Tsuyoshi Takato, Kazuto Hoshi
Glial fibrillary acidic protein (GFAP) is an intermediate filament that is expressed in specifically expressed auricular chondrocytes, which are good cell sources of cartilage regenerative medicine. Although our group uses GFAP as a biomarker of matrix production in the cultured auricular chondrocytes, the biological roles of GFAP in auricular chondrocytes has remained unknown. In this study, we demonstrated the biological functions of GFAP in the human and mouse derived auricles to clarify the significance and role with the chondrocytes of GFAP in order to provide useful information for reliable and safe regenerative medicine...
January 7, 2017: Journal of Cellular Physiology
https://www.readbyqxmd.com/read/28032171/iatrogenic-through-and-through-conchal-defect-secondary-to-auricular-cartilage-graft
#2
Hyung-Suk Ro, Si-Gyun Roh, Jin Yong Shin, Nae-Ho Lee, Kyung-Moo Yang
BACKGROUND: Over the past few years, conchal cartilage has been most often used in rhinoplasty. The donor site complications following conchal cartilage graft harvesting are scar formation, hematoma formation, and delayed wound healing, although hematoma is one of the most important and common complications. A complete conchal defect as a complication of auricular cartilage graft harvesting has not been previously reported in the literature. The authors report an unusual case of an iatrogenic conchal defect resulting from conchal cartilage graft harvesting that was treated using a posterior auricular island flap...
December 28, 2016: Aesthetic Plastic Surgery
https://www.readbyqxmd.com/read/27990114/sparing-surgery-for-the-successful-treatment-of-thyroid-papillary-carcinoma-invading-the-trachea-a-case-report
#3
Denis Kulbakin, Timofey Chekalkin, Marat Muhamedov, Evgeniy Choynzonov, Ji-Hoon Kang, Seung-Baik Kang, Victor Gunther
Published reports on salvage treatment for trachea reconstruction after total thyroidectomy or partial tracheotomy are available, some of them using structures of the trachea itself, auricular cartilage, a musculocutaneous flap, or other methods. In our report, we emphasize the importance of a search for a new material and approach for sparing surgery. The purpose of this article is to describe a case of a successful sparing surgery in a patient with advanced thyroid papillary carcinoma invading the trachea...
September 2016: Case Reports in Oncology
https://www.readbyqxmd.com/read/27987254/application-of-free-serratus-anterior-fascial-flap-for-reconstruction-of-ear-deformity-due-to-hemifacial-microsomia-a-report-of-two-cases
#4
Takashi Nuri, Koichi Ueda, Akira Yamada
Reconstructing congenital auricular defects due to hemifacial microsomia (HFM) is often required to deal with low hairline and defects of the temporal fascia/muscular systems. In this report, we present two cases of HFM patients (16-year-old and 20-year-old) with positional anomaly of the remnant lobule and 95% low hairline, who were treated with serratus anterior fascial flap (SFF) at the second stage of auricular construction. At the first stage, 3D costal cartilage framework was placed following the removal of hair-bearing skin, and was resurfaced with the pericranial flap...
December 17, 2016: Microsurgery
https://www.readbyqxmd.com/read/27930470/correction-of-lying-ears-by-augmentation-of-the-conchoscaphal-angle
#5
Sung-Eun Kim, Chi-Ho Yeo, Taegon Kim, Yong-Ha Kim, Jun Ho Lee, Kyu-Jin Chung
Lying ears are defined as ears that protrude less from the head, and in frontal view, are characterized by lateral positioning of antihelical contour relative to the helical rim. These aesthetically displeasing ears require correction in accord with the goals of otoplasty stated by McDowell. The authors present a case of lying ears treated by correcting the conchomastoid angle using Z-plasty, resection of posterior auricular muscle, and correction of the conchoscaphal angle by releasing cartilage using 2 full-thickness incisions and grafting of a conchal cartilage spacer...
December 7, 2016: Journal of Craniofacial Surgery
https://www.readbyqxmd.com/read/27917821/optimizing-cell-sourcing-for-clinical-translation-of-tissue-engineered-ears
#6
Kerry A Morrison, Benjamin P Cohen, Ope Asanbe, Xue Dong, Alice Harper, Lawrence J Bonassar, Jason A Spector
: Background . Currently, the major impediment to clinical translation of our previously described platform for the fabrication of high fidelity, patient-specific tissue engineered ears is the development of a clinically optimal cell sourcing strategy. A limited autologous auricular chondrocyte (AuC) supply in conjunction with rapid chondrocyte de-differentiation during in vitro expansion currently makes clinical translation more challenging. Mesenchymal stem cells (MSCs) offer significant promise due to their inherent chondrogenic potential, and large availability through minimally invasive procedures...
December 5, 2016: Biofabrication
https://www.readbyqxmd.com/read/27903413/fenestration-of-auricular-cartilage-grafts-to-aid-healing-of-alar-wounds-by-secondary-intention
#7
A M Flynn, R B M Barry
No abstract text is available yet for this article.
November 27, 2016: British Journal of Oral & Maxillofacial Surgery
https://www.readbyqxmd.com/read/27900891/chondrogenesis-of-human-adipose-derived-stem-cells-for-future-microtia-repair-using-co-culture-technique
#8
Bee See Goh, Siti Nurhadis Che Omar, Muhammad Azhan Ubaidah, Lokman Saim, Shamsul Sulaiman, Kien Hui Chua
CONCLUSION: In conclusion, these result showed HADSCs could differentiate into chondrocytes-like cells, dependent on signaling induced by TGF-β3 and chondrocytes. This is a promising result and showed that HADSCs is a potential source for future microtia repair. The technique of co-culture is a positive way forward to assist the microtia tissue. OBJECTIVE: Reconstructive surgery for the repair of microtia still remains the greatest challenge among the surgeons...
November 30, 2016: Acta Oto-laryngologica
https://www.readbyqxmd.com/read/27899950/bone-anchored-titanium-implants-in-patients-with-auricular-defects-three-years-and-27-patients-experience
#9
Emilio Mevio, Luca Facca, Stefano Schettini, Mauro Mullace
Different surgical solutions have been proposed for reconstruction of the auricle following loss of the pinna through traumatic injury or neoplastic disease or in patients with congenital defects. Surgical treatment may involve the insertion of an autogenous rib cartilage framework or the use of a porous polymer material inserted into an expanded postauricular flap. Reconstruction with rib cartilage has yielded good results but requires more than one surgical step, and adverse events can occur both at the donor and at the acceptor site; cases of prosthesis rejection have also been described following application of the polymeric prosthesis...
2016: International Journal of Otolaryngology
https://www.readbyqxmd.com/read/27879225/efficacy-of-posterior-canal-wall-reconstruction-using-autologous-auricular-cartilage-and-bone-p%C3%A3-t%C3%A3-in-chronic-otitis-media-with-cholesteatoma
#10
Min Kwan Baek, Sung Ho Choi, Dong Young Kim, Chang Hyun Cho, Yong Woo Kim, Kwang Ha Moon, Ju Hyoung Lee
OBJECTIVE: This study was designed to investigate the long-term results using the technique of canal wall up mastoidectomy and reconstruction of the posterior canal wall using bone pâté and auricular cartilage in the treatment of chronic otitis media with cholesteatoma. MATERIALS AND METHODS: A retrospective review was performed on 42 patients who underwent canal wall up mastoidectomy and posterior canal wall reconstruction at a single institution between November 2005 and November 2012...
November 23, 2016: Journal of International Advanced Otology
https://www.readbyqxmd.com/read/27875514/domino-flaps-for-repairing-of-secondary-bilateral-cleft-lip-with-severe-columella-deformity
#11
Jiao Wei, Cheng-An Chiang, Da Zhou, Qingfeng Li, Kai Liu
The patients with secondary bilateral cleft lip and nasal deformity always suffer from a serious part of the horizontal and vertical soft tissue deficiencies in the upper lip and nose, especially the columella. Normally, the Abbe flap is used to increase the soft tissue volume of upper lip. However, how to reconstruct the sever columella deficient, how to make full use of the Abbe flap and the remaining soft tissue of the upper lip, are always the problems that need to be solved by plastic surgeons. Twenty-nine patients with secondary bilateral cleft lip and severe columella deficiency were simultaneously reconstructed with several local flaps like dominos that was called "Domino sliding flaps...
January 2017: Journal of Craniofacial Surgery
https://www.readbyqxmd.com/read/27868204/bioengineering-pediatric-scaffold-free-auricular-cartilaginous-constructs
#12
Pedram Akbari, Stephen D Waldman, Sharon L Cushing, Blake C Papsin, Evan J Propst, Joanna F Weber, Herman Yeger, Walid A Farhat
OBJECTIVE: The use of exogenous materials as scaffolds in cartilage tissue engineering has limited the clinical application of resultant constructs due to the risk of postoperative complications. In an effort to minimize such complications, we aim to generate human, scaffold-free auricular cartilaginous constructs. STUDY DESIGN: Laboratory study using pediatric auricular cartilage. METHODS: Remnant, normal pediatric auricular cartilage samples that would have otherwise been discarded were collected and digested to free cells...
November 21, 2016: Laryngoscope
https://www.readbyqxmd.com/read/27865143/the-postauricular-fasciocutaneous-flap-with-an-adipofascial-extension-a-case-report
#13
Mohammed M Al-Qattan, Nawarah Al-Arfaj
INTRODUCTION: A complex defect on the anterior surface of the ear requires flap cover; such as the postauricular skin flap. The postauricular skin flap has never been used with an adipofascial extension. PRESENTATION OF CASE: A 5-year old boy was involved in a car accident resulting in an exposed cartilage of the upper part of the right ear. The defect was covered with a post-auricular fasciocutaneous flap with an adipofascial extension. The adipofascial part of the flap was covered with a skin graft...
2016: International Journal of Surgery Case Reports
https://www.readbyqxmd.com/read/27847738/temporomandibular-joint-chondrosarcoma-a-case-report-and-literature-review
#14
Kyungjin Lee, Seong Hwan Kim, Soung-Min Kim, Hoon Myoung
Chondrosarcoma is a malignant tumor that originates from cartilaginous cells and is characterized by cartilage formation. Only 5% to 10% of chondrosarcoma occurs in the head and neck area, and it is uncommon in the temporomandibular joint area. This report describes an unusual case with a rare, large chondrosarcoma in a 47-year-old woman who presented with painless swelling and trismus. Computed tomography showed a large mass approximately 8.5×6.0 cm in size arising adjacent to the lateral pterygoid plate and condyle...
October 2016: Journal of the Korean Association of Oral and Maxillofacial Surgeons
https://www.readbyqxmd.com/read/27780641/three-layer-reconstruction-of-lower-third-nasal-defects-using-forehead-flap-reversed-nasolabial-flap-and-auricular-cartilage
#15
A Ghassemi, S S Ahmed, H Ghanepur, A Modabber
The reconstruction of a full-thickness defect of the distal third of the nose requires the restoration of all three anatomical layers. A practical method for three-layer reconstruction of the lower third of the nose and the long-term results of this technique are presented herein. A combined reconstruction technique was utilized, including a reverse subcutaneous pedicled nasolabial flap to restore the nasal mucosa, an auricular cartilage graft for structural support, and a forehead flap for cutaneous coverage of the defect...
January 2017: International Journal of Oral and Maxillofacial Surgery
https://www.readbyqxmd.com/read/27752197/use-of-auricular-cartilage-for-closure-of-oroantral-fistula-a-prospective-clinical-study
#16
Hari Ram, Hardik Makadia, Gagan Mehta, Shadab Mohammad, Rakesh Kumar Singh, Nimisha Singh, Geeta Singh
INTRODUCTION: The term oro-antral fistula is understood to mean of fistular canal covered with epithelia which may or may not be filled with granulation tissue or polyposis of the sinus mucous membrane. With the presence of a fistula the sinus is permanently open, which enables the passage of microbial flora of the oral cavity into the maxillary sinus and the occurrence of inflammation with all possible consequences. Every now and then various researchers have proposed innumerable techniques to treat this defect...
September 2016: Journal of Maxillofacial and Oral Surgery
https://www.readbyqxmd.com/read/27739349/costal-cartilage-graft-with-perichondrium-a-possible-anti-adhesive-material
#17
Norio Fukuda, Hirotaka Asato, Kohei Umekawa, Goro Takada, Takeshi Kan, Shoichi Sasaki
BACKGROUND: Adhesion occurs as a part of the wound healing process, but it sometimes compromises patients' daily activities. The authors were looking for materials and methods that could prevent adhesion, and noticed that the costal cartilage has possibility. The anti-adhesive property of the costal cartilage was examined histologically. METHODS: Thirty-five patients with microtia who provided consent for participating in this study were enrolled between April 2008 and March 2015...
October 14, 2016: Journal of Plastic Surgery and Hand Surgery
https://www.readbyqxmd.com/read/27714497/mechanisms-of-ear-trauma-and-reconstructive-techniques-in-105-consecutive-patients
#18
Michail N Kolodzynski, Moshe Kon, Silvan Egger, Corstiaan C Breugem
Acquired auricular deformities may diminish facial esthetics and cause psychological distress. The aim of this article is to provide an overview of the type of injuries and applied reconstructive techniques in a large academic hospital in The Netherlands. A retrospective chart review was conducted for the last 105 patients who underwent auricular reconstruction for an acquired deformity. Data concerning gender, affected side, cause of injury, anatomical region, the previous and further surgeries, type of cartilage, and skin cover used were collected and analyzed...
October 6, 2016: European Archives of Oto-rhino-laryngology
https://www.readbyqxmd.com/read/27708954/relapsing-polychondritis
#19
REVIEW
Hakan Emmungil, Sibel Zehra Aydın
Relapsing polychondritis (RPC) is a unique and rarely observed autoimmune condition regarded as recurrent extensive chondritis of the auricular, nasal, and tracheal cartilages. Moreover, heart, main arteries, skin, and eyes may be involved. Several forms of clinical manifestations may be seen, and the pathogenesis still remains anonymous. A concomitant disease, particularly myelodysplasia or other systemic autoimmune disease can be detected in one-third of the patients with RPC. The treatment of RPC should be considered on personal basis and classified according to disease activity and severity...
December 2015: European Journal of Rheumatology
https://www.readbyqxmd.com/read/27686647/cutaneous-nodular-fasciitis-with-genetic-analysis-a-case-series
#20
Erica Kumar, Nimesh R Patel, Elizabeth G Demicco, Judith V M G Bovee, Andre M Olivera, Dolores H Lopez-Terrada, Steven D Billings, Alexander J Lazar, Wei-Lien Wang
Nodular fasciitis is a benign self-limited myofibroblastic neoplasm, which usually involves the upper extremities and trunk of young patients. These tumors have been shown to harbor a translocation involving the MYH9 and USP6 genes, leading to overexpression of the latter. We report seven cases of nodular fasciitis with cutaneous presentations. All cases involved the dermis, with six involving the superficial subcutis, and one auricular tumor extending into cartilage. All cases showed USP6 rearrangement by fluorescence in situ hybridization; in two of three cases, the characteristic MYH9-USP6 fusion was shown by RT-PCR...
December 2016: Journal of Cutaneous Pathology
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