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https://www.readbyqxmd.com/read/28808164/supranuclear-gaze-palsy-and-horizontal-ocular-oscillations-in-creutzfeldt-jakob-disease
#1
Asya I Wallach, Hannah Park, Janet C Rucker, Horacio Kaufmann
No abstract text is available yet for this article.
August 15, 2017: Neurology
https://www.readbyqxmd.com/read/28794985/vertical-gaze-palsy-due-to-medication-error
#2
Shishir Rao, Meghan Harper-Shankie, Rajkumar Agarwal
We present a teenage boy with recent onset of seizures, who was erroneously treated with a large dose of an antiseizure medication as a result of drug mix-up. The ensuing drug toxicity caused vertical gaze palsy, an unusual manifestation related to overdose of the agent. Timely recognition of the error and discontinuation of the drug resulted in complete recovery to baseline.
2017: Epilepsy & Behavior Case Reports
https://www.readbyqxmd.com/read/28744253/novel-eye-movement-disorders-in-whipple-s-disease-staircase-horizontal-saccades-gaze-evoked-nystagmus-and-esotropia
#3
Aasef G Shaikh, Fatema F Ghasia
Whipple's disease, a rare systemic infectious disorder, is complicated by the involvement of the central nervous system in about 5% of cases. Oscillations of the eyes and the jaw, called oculo-masticatory myorhythmia, are pathognomonic of the central nervous system involvement but are often absent. Typical manifestations of the central nervous system Whipple's disease are cognitive impairment, parkinsonism mimicking progressive supranuclear palsy with vertical saccade slowing, and up-gaze range limitation. We describe a unique patient with the central nervous system Whipple's disease who had typical features, including parkinsonism, cognitive impairment, and up-gaze limitation; but also had diplopia, esotropia with mild horizontal (abduction more than adduction) limitation, and vertigo...
2017: Frontiers in Neurology
https://www.readbyqxmd.com/read/28728290/-advances-in-research-of-divergence-insufficiency
#4
Y P Li, W Zhang
Divergence insufficiency is acquired esotropia at distance fixation with symptomatic uncrossed diplopia but fusion at near. It can be divided into two forms: primary isolated form and secondary form associated with neurologic abnormalities, also called divergence palsy. The clinical features of divergence insufficiency include small esotropia only at distance but orthotropia or small esophoria at near, comitant deviation at lateral gaze, reduced divergence fusion, full abduction and normal saccadic velocities in abduction...
July 11, 2017: [Zhonghua Yan Ke za Zhi] Chinese Journal of Ophthalmology
https://www.readbyqxmd.com/read/28713055/anterior-and-nasal-transposition-of-inferior-oblique-muscle-in-cases-of-superior-oblique-palsy
#5
Rohit Saxena, Medha Sharma, Digvijay Singh, Pradeep Sharma
PURPOSE: To report long-term outcome of inferior oblique anterior and nasal transposition in superior oblique palsy. METHODS: The medical records of patients with superior oblique palsy who underwent inferior oblique anterior nasal transposition were reviewed retrospectively. A comprehensive ophthalmic evaluation, including prism bar cover test and measurement of torsion, was performed for all cases. One-year postoperative results were evaluated for alignment in primary gaze, contralateral gaze, and upgaze; reduction in inferior oblique overaction and changes in fundus torsion to assess long-term outcome of the procedure...
July 13, 2017: Journal of AAPOS: the Official Publication of the American Association for Pediatric Ophthalmology and Strabismus
https://www.readbyqxmd.com/read/28702192/freezing-of-gait-is-an-early-clinical-feature-of-progressive-supranuclear-palsy
#6
Yasushi Osaki, Yukari Morita, Yuka Miyamoto, Kounosuke Furuta, Hirokazu Furuya
BACKGROUND AND AIM: Early clinical diagnosis of progressive supranuclear palsy (PSP) remains challenging. AIM: We attempted to identify any sign or symptom to diagnose PSP earlier. METHODS: A total of 401 patients, 40 with PSP and 361 with other neurodegenerative disorders, were included. We followed these patients for at least 1 year since 2009. We reviewed the signs and symptoms of patients with PSP in a standardized manner, and observed four manifestations: "vertical supranuclear gaze abnormality," "movement disorders," "pseudobulbar palsy" and "dementia of frontal type...
May 2017: Neurology and Clinical Neuroscience
https://www.readbyqxmd.com/read/28690585/saccadic-impairments-in-patients-with-the-norrbottnian-form-of-gaucher-s-disease-type-3
#7
Josefine Blume, Stanislav Beniaminov, Cecilia Kämpe Björkvall, Maciej Machaczka, Per Svenningsson
BACKGROUND: Chronic neuronopathic Gaucher's disease type 3 (GD3) is relatively frequent in northern Sweden. Besides multiple other neurological symptoms, horizontal gaze palsy or oculomotor apraxia is common in GD3. OBJECTIVE: To characterize the saccades in patients with Norrbottnian GD3 with respect to their neurological and cognitive status using a computer-based eye-tracking technique. METHODS: Horizontal and vertical reflexive saccades as well as antisaccades of nine GD3 patients [4M/5F; 41...
2017: Frontiers in Neurology
https://www.readbyqxmd.com/read/28687220/one-vs-two-muscle-surgery-for-presumed-unilateral-fourth-nerve-palsy-associated-with-moderate-angle-hyperdeviations
#8
David L Nash, Sarah R Hatt, David A Leske, Laura May, Erick D Bothun, Brian G Mohney, Michael C Brodsky, Jonathan M Holmes
PURPOSE: To compare one-muscle versus two-muscle surgery for moderate-angle hyperdeviations due to presumed unilateral fourth nerve palsy. DESIGN: Retrospective chart review METHODS: 73 patients (5 to 86 years) underwent either one- or two-muscle surgery at our institution, for moderate hyperdeviation, due to presumed unilateral fourth nerve palsy, measuring 14 to 25 PD in straight ahead gaze at distance fixation. Six week and 1-year motor success was defined as zero vertical deviation or 1-4 PD undercorrection at distance, overcorrection as any reversal of hypertropia, and undercorrection as >4 PD...
July 4, 2017: American Journal of Ophthalmology
https://www.readbyqxmd.com/read/28681792/vertical-gaze-palsy-due-to-acute-bilateral-thalamic-infarct-without-midbrain-ischemia
#9
Shakya Bhattacharjee, Kher Lik Ng
No abstract text is available yet for this article.
July 2017: Neurology India
https://www.readbyqxmd.com/read/28681278/are-we-overlooking-masked-bilateral-congenital-superior-oblique-palsy-in-children-is-it-possible-to-diagnose-before-surgery
#10
Kadriye Erkan Turan, Hande Taylan Sekeroglu, Ali Sefik Sanac
PURPOSE: To describe the characteristics of children who had subsequent contralateral superior oblique underaction (SOUA) and inferior oblique overaction (IOOA) after unilateral inferior oblique weakening surgery and to identify suggestive clinical features for masked bilateral fourth nerve palsy. METHODS: The medical records of children who underwent unilateral inferior oblique tenotomy as a single procedure for unilateral superior oblique palsy were all reviewed...
July 5, 2017: International Ophthalmology
https://www.readbyqxmd.com/read/28661425/characterizing-computer-access-using-a-one-channel-eeg-wireless-sensor
#11
Alberto J Molina-Cantero, Jaime Guerrero-Cubero, Isabel M Gómez-González, Manuel Merino-Monge, Juan I Silva-Silva
This work studies the feasibility of using mental attention to access a computer. Brain activity was measured with an electrode placed at the Fp1 position and the reference on the left ear; seven normally developed people and three subjects with cerebral palsy (CP) took part in the experimentation. They were asked to keep their attention high and low for as long as possible during several trials. We recorded attention levels and power bands conveyed by the sensor, but only the first was used for feedback purposes...
June 29, 2017: Sensors
https://www.readbyqxmd.com/read/28634598/previously-unrecognized-behavioral-phenotype-in-gaucher-disease-type-3
#12
Magy Abdelwahab, Michael Potegal, Elsa G Shapiro, Igor Nestrasil
OBJECTIVE: To provide a comprehensive description of abnormal behaviors in patients with Gaucher disease type 3 (GD3) and relate these behaviors to demographic, neurodevelopmental, and neurologic characteristics. METHODS: Thirty-four Egyptian patients with GD3 (mean age of 7.9 years) were enrolled in the study. They were selected based on parent report and/or physician observation of one or more abnormal behaviors documented in 2 settings and by 2 different individuals and/or by video recording...
June 2017: Neurology. Genetics
https://www.readbyqxmd.com/read/28632466/neuropsychological-profiles-of-children-with-cerebral-palsy
#13
Kristine Stadskleiv, Reidun Jahnsen, Guro L Andersen, Stephen von Tetzchner
PURPOSE: To explore factors contributing to variability in cognitive functioning in children with cerebral palsy (CP). METHOD: A geographical cohort of 70 children with CP was assessed with tests of language comprehension, visual-spatial reasoning, attention, working memory, memory, and executive functioning. Mean age was 9;9 years (range 5;1-17;7), 54.3% were girls, and 50.0% had hemiplegic, 25.7% diplegic, 12.9% quadriplegic, and 11.4% dyskinetic CP. For the participants with severe motor impairments, assessments were adapted for gaze pointing...
February 21, 2017: Developmental Neurorehabilitation
https://www.readbyqxmd.com/read/28574146/niemann-pick-type-c-as-a-cause-of-progressive-intellectual-and-neurological-deterioration-in-childhood
#14
Anne Marie Winstone, Lesley Ann Stellitano, Christopher Michael Verity
AIM: To describe the cases of Niemann-Pick type C (NP-C) disease in a United Kingdom epidemiological study of progressive intellectual and neurological deterioration in childhood. METHOD: Paediatricians notified cases via the British Paediatric Surveillance Unit between 1997 and 2015. RESULTS: Fifty-three NP-C patients were identified: 29 females, 24 males. Fifteen cases had a systemic presentation (neonatal jaundice and/or hepatosplenomegaly)...
June 2, 2017: Developmental Medicine and Child Neurology
https://www.readbyqxmd.com/read/28544256/intrinsic-functional-connectivity-alterations-in-progressive-supranuclear-palsy-differential-effects-in-frontal-cortex-motor-and-midbrain-networks
#15
Johannes Rosskopf, Martin Gorges, Hans-Peter Müller, Dorothée Lulé, Ingo Uttner, Albert C Ludolph, Elmar Pinkhardt, Freimut D Juengling, Jan Kassubek
BACKGROUND: The topography of functional network changes in progressive supranuclear palsy can be mapped by intrinsic functional connectivity MRI. The objective of this study was to study functional connectivity and its clinical and behavioral correlates in dedicated networks comprising the cognition-related default mode and the motor and midbrain functional networks in patients with PSP. METHODS: Whole-brain-based "resting-state" functional MRI and high-resolution T1-weighted magnetic resonance imaging data together with neuropsychological and video-oculographic data from 34 PSP patients (22 with Richardson subtype and 12 with parkinsonian subtype) and 35 matched healthy controls were subjected to network-based functional connectivity and voxel-based morphometry analysis...
July 2017: Movement Disorders: Official Journal of the Movement Disorder Society
https://www.readbyqxmd.com/read/28499831/resolution-of-hypertropia-with-correction-of-consecutive-horizontal-deviation
#16
Rui Hao, Kanxing Zhao, Wei Zhang
BACKGROUND: To study the resolution of hypertropia in patients who undergo horizontal deviation surgery for consecutive esotropia or consecutive exotropia. METHODS: We retrospectively reviewed the records of 23 patients with consecutive esotropia or exotropia who had concomitant vertical tropia. All patients had had surgery for horizontal deviation that required further surgery to correct consecutive horizontal strabismus and had a minimum of six months of postoperative follow-up...
May 9, 2017: Journal of the Chinese Medical Association: JCMA
https://www.readbyqxmd.com/read/28479825/acute-bilateral-supranuclear-vertical-gaze-palsy-vertical-one-and-a-one-syndrome-report-of-three-cases
#17
Rohan R Mahale, Kiran Buddaraju, Anish Mehta, Mahendra Javali, Purushottam Acharya, Rangasetty Srinivasa
No abstract text is available yet for this article.
April 2017: Journal of Neurosciences in Rural Practice
https://www.readbyqxmd.com/read/28424453/comorbid-human-immunodeficiency-virus-hiv-and-muscle-specific-kinase-musk-myasthenia-gravis-a-case-report-and-literature-review
#18
Michael Sherpa, Ravi K Metai, Viki Kumar, Tinu Hirachan, Kawser U Ahmed, Sharon J Atkinson
BACKGROUND HIV infections with concomitant immunologically-mediated disorders have been frequently described but there has been little research on the association between HIV and myasthenia gravis. MuSK myasthenia gravis coexisting with HIV is an even a rarer entity and can occur as a part of immune restoration disease. We report the case of a patient with asymptomatic HIV infection who presented with new-onset MuSK myasthenia gravis. CASE REPORT A 44-year-old African-American woman with HIV since 2004 and on highly active antiretroviral therapy (HAART) presented to the ED with complains of double vision and difficulty swallowing for 2 weeks...
April 20, 2017: American Journal of Case Reports
https://www.readbyqxmd.com/read/28421028/adult-onset-niemann-pick-disease-type-c-rapid-treatment-initiation-advised-but-early-diagnosis-remains-difficult
#19
Tobias Piroth, Kai Boelmans, Florian Amtage, Michel Rijntjes, Anna Wierciochin, Thomas Musacchio, Cornelius Weiller, Jens Volkmann, Stephan Klebe
Niemann-Pick type C disease (NP-C) presents with heterogeneous neurological and psychiatric symptoms. Adult onset is rare and possibly underdiagnosed due to frequent lack of specific and obvious key symptoms. For both early and adolescent/adult onset, the available data from studies and case reports describe a positive effect of Miglustat (symptom relief or stabilization). However, due to the low frequency of NP-C, experience with this therapy is still limited. We describe two adult-onset cases of NP-C. In both cases, vertical supranuclear gaze palsy was not recognized at symptom onset...
2017: Frontiers in Neurology
https://www.readbyqxmd.com/read/28415165/progressive-supranuclear-gaze-palsy-with-predominant-cerebellar-ataxia-a-case-series-with-videos
#20
Zheyu Xu, Tchoyoson C C Lim, Wing Lok Au, Louis C S Tan
Progressive supranuclear palsy (PSP) with predominant cerebellar ataxia (PSP-C) is a rare phenotype of PSP. The clinical and radiological features of this disorder remain poorly characterized. Through a retrospective case series, we aim to characterize the clinical and radiological features of PSP-C. Four patients with PSP-C were identified: patients who presented with prominent cerebellar dysfunction that disappeared with the progression of the disease. Supranuclear gaze palsy occurred at a mean of 2.0 ± 2...
May 2017: Journal of Movement Disorders
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