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https://www.readbyqxmd.com/read/28878733/clinical-approach-to-supranuclear-brainstem-saccadic-gaze-palsies
#1
REVIEW
Alexandra Lloyd-Smith Sequeira, John-Ross Rizzo, Janet C Rucker
Failure of brainstem supranuclear centers for saccadic eye movements results in the clinical presence of a brainstem-mediated supranuclear saccadic gaze palsy (SGP), which is manifested as slowing of saccades with or without range of motion limitation of eye movements and as loss of quick phases of optokinetic nystagmus. Limitation in the range of motion of eye movements is typically worse with saccades than with smooth pursuit and is overcome with vestibular-ocular reflexive eye movements. The differential diagnosis of SGPs is broad, although acute-onset SGP is most often from brainstem infarction and chronic vertical SGP is most commonly caused by the neurodegenerative condition progressive supranuclear palsy...
2017: Frontiers in Neurology
https://www.readbyqxmd.com/read/28873936/parent-perception-of-two-eye-gaze-control-technology-systems-in-young-children-with-cerebral-palsy-pilot-study
#2
Petra Karlsson, Margaret Wallen
Eye-gaze control technology enables people with significant physical disability to access computers for communication, play, learning and environmental control. This pilot study used a multiple case study design with repeated baseline assessment and parents' evaluations to compare two eye-gaze control technology systems to identify any differences in factors such as ease of use and impact of the systems for their young children. Five children, aged 3 to 5 years, with dyskinetic cerebral palsy, and their families participated...
2017: Studies in Health Technology and Informatics
https://www.readbyqxmd.com/read/28871881/a-child-with-right-ear-pain-and-a-gaze-palsy
#3
John Solms, Monaliza Evangelista, Anand Gourishankar
No abstract text is available yet for this article.
October 2017: Clinical Pediatrics
https://www.readbyqxmd.com/read/28862491/eye-gaze-control-technology-for-children-adolescents-and-adults-with-cerebral-palsy-with-significant-physical-disability-findings-from-a-systematic-review
#4
Petra Karlsson, Abigail Allsop, Betty-Jean Dee-Price, Margaret Wallen
PURPOSE: The primary objective of this systematic review was to examine the effectiveness of eye-gaze control technology for facilitating communication across different social contexts for people with cerebral palsy and significant physical disability. METHODS: Systematic review. RESULTS: The search identified 756 potentially eligible articles, of which two, low level articles were eligible. One study reported positive results for achieving communication goals for children with cerebral palsy...
September 1, 2017: Developmental Neurorehabilitation
https://www.readbyqxmd.com/read/28841851/combined-brown-syndrome-and-superior-oblique-palsy-without-a-trochlear-nerve-case-report
#5
Hee Kyung Yang, Jae Hyoung Kim, Ji-Soo Kim, Jeong-Min Hwang
BACKGROUND: Congenital Brown syndrome is characterized by limited elevation particularly during adduction. The pathogenesis of congenital Brown syndrome is still controversial. CASE PRESENTATION: A 6-year-old boy had been tilting his head to the left since infancy. He showed right hypertropia (RHT) of 2 prism diopters (Δ) in the primary position. He showed RHT 6Δ in right gaze, RHT 2Δ in left gaze, RHT 12Δ in right head tilt, and orthotropia in left head tilt...
August 25, 2017: BMC Ophthalmology
https://www.readbyqxmd.com/read/28832711/horizontal-gaze-palsy-and-progressive-scoliosis-magnetic-resonance-imaging-features-and-surgical-treatment
#6
Benedito Jamilson Araújo Pereira, Ulysses Caus Batista, Fúlvio Nicolau Bechelli, Carlos Alberto Afonso Ribeiro, Carlos Vanderlei Medeiros de Holanda, Paulo Eduardo Carvalho Galvão
No abstract text is available yet for this article.
August 17, 2017: Einstein
https://www.readbyqxmd.com/read/28830896/patient-with-niemann-pick-disease-type-c-over-20-years-follow-up
#7
Kazuo Abe, Norio Sakai
We report a 37-year-old woman with Niemann-Pick disease type C (NPC) 1. At the age of 8 years, she presented slow running followed by both fingers dystonia at the age of 10 years. At the age of 16 years, she developed declined scholastic achievement. On her first visit at the age of 17 years, she showed dystonia, ataxic gait and vertical supranuclear gaze palsy. We suspected it was NPC. She presented atrophies in the frontal lobes, brainstem and cerebellum in a brain MRI. She presented hepatomegalies and splenomegalies in an abdominal CT...
August 22, 2017: BMJ Case Reports
https://www.readbyqxmd.com/read/28808164/supranuclear-gaze-palsy-and-horizontal-ocular-oscillations-in-creutzfeldt-jakob-disease
#8
Asya I Wallach, Hannah Park, Janet C Rucker, Horacio Kaufmann
No abstract text is available yet for this article.
August 15, 2017: Neurology
https://www.readbyqxmd.com/read/28794985/vertical-gaze-palsy-due-to-medication-error
#9
Shishir Rao, Meghan Harper-Shankie, Rajkumar Agarwal
We present a teenage boy with recent onset of seizures, who was erroneously treated with a large dose of an antiseizure medication as a result of drug mix-up. The ensuing drug toxicity caused vertical gaze palsy, an unusual manifestation related to overdose of the agent. Timely recognition of the error and discontinuation of the drug resulted in complete recovery to baseline.
2017: Epilepsy & Behavior Case Reports
https://www.readbyqxmd.com/read/28744253/novel-eye-movement-disorders-in-whipple-s-disease-staircase-horizontal-saccades-gaze-evoked-nystagmus-and-esotropia
#10
Aasef G Shaikh, Fatema F Ghasia
Whipple's disease, a rare systemic infectious disorder, is complicated by the involvement of the central nervous system in about 5% of cases. Oscillations of the eyes and the jaw, called oculo-masticatory myorhythmia, are pathognomonic of the central nervous system involvement but are often absent. Typical manifestations of the central nervous system Whipple's disease are cognitive impairment, parkinsonism mimicking progressive supranuclear palsy with vertical saccade slowing, and up-gaze range limitation. We describe a unique patient with the central nervous system Whipple's disease who had typical features, including parkinsonism, cognitive impairment, and up-gaze limitation; but also had diplopia, esotropia with mild horizontal (abduction more than adduction) limitation, and vertigo...
2017: Frontiers in Neurology
https://www.readbyqxmd.com/read/28728290/-advances-in-research-of-divergence-insufficiency
#11
Y P Li, W Zhang
Divergence insufficiency is acquired esotropia at distance fixation with symptomatic uncrossed diplopia but fusion at near. It can be divided into two forms: primary isolated form and secondary form associated with neurologic abnormalities, also called divergence palsy. The clinical features of divergence insufficiency include small esotropia only at distance but orthotropia or small esophoria at near, comitant deviation at lateral gaze, reduced divergence fusion, full abduction and normal saccadic velocities in abduction...
July 11, 2017: [Zhonghua Yan Ke za Zhi] Chinese Journal of Ophthalmology
https://www.readbyqxmd.com/read/28713055/anterior-and-nasal-transposition-of-inferior-oblique-muscle-in-cases-of-superior-oblique-palsy
#12
Rohit Saxena, Medha Sharma, Digvijay Singh, Pradeep Sharma
PURPOSE: To report long-term outcome of inferior oblique anterior and nasal transposition in superior oblique palsy. METHODS: The medical records of patients with superior oblique palsy who underwent inferior oblique anterior nasal transposition were reviewed retrospectively. A comprehensive ophthalmic evaluation, including prism bar cover test and measurement of torsion, was performed for all cases. One-year postoperative results were evaluated for alignment in primary gaze, contralateral gaze, and upgaze; reduction in inferior oblique overaction and changes in fundus torsion to assess long-term outcome of the procedure...
August 2017: Journal of AAPOS: the Official Publication of the American Association for Pediatric Ophthalmology and Strabismus
https://www.readbyqxmd.com/read/28702192/freezing-of-gait-is-an-early-clinical-feature-of-progressive-supranuclear-palsy
#13
Yasushi Osaki, Yukari Morita, Yuka Miyamoto, Kounosuke Furuta, Hirokazu Furuya
BACKGROUND AND AIM: Early clinical diagnosis of progressive supranuclear palsy (PSP) remains challenging. AIM: We attempted to identify any sign or symptom to diagnose PSP earlier. METHODS: A total of 401 patients, 40 with PSP and 361 with other neurodegenerative disorders, were included. We followed these patients for at least 1 year since 2009. We reviewed the signs and symptoms of patients with PSP in a standardized manner, and observed four manifestations: "vertical supranuclear gaze abnormality," "movement disorders," "pseudobulbar palsy" and "dementia of frontal type...
May 2017: Neurology and Clinical Neuroscience
https://www.readbyqxmd.com/read/28690585/saccadic-impairments-in-patients-with-the-norrbottnian-form-of-gaucher-s-disease-type-3
#14
Josefine Blume, Stanislav Beniaminov, Cecilia Kämpe Björkvall, Maciej Machaczka, Per Svenningsson
BACKGROUND: Chronic neuronopathic Gaucher's disease type 3 (GD3) is relatively frequent in northern Sweden. Besides multiple other neurological symptoms, horizontal gaze palsy or oculomotor apraxia is common in GD3. OBJECTIVE: To characterize the saccades in patients with Norrbottnian GD3 with respect to their neurological and cognitive status using a computer-based eye-tracking technique. METHODS: Horizontal and vertical reflexive saccades as well as antisaccades of nine GD3 patients [4M/5F; 41...
2017: Frontiers in Neurology
https://www.readbyqxmd.com/read/28687220/one-vs-two-muscle-surgery-for-presumed-unilateral-fourth-nerve-palsy-associated-with-moderate-angle-hyperdeviations
#15
David L Nash, Sarah R Hatt, David A Leske, Laura May, Erick D Bothun, Brian G Mohney, Michael C Brodsky, Jonathan M Holmes
PURPOSE: To compare one-muscle versus two-muscle surgery for moderate-angle hyperdeviations due to presumed unilateral fourth nerve palsy. DESIGN: Retrospective chart review METHODS: 73 patients (5 to 86 years) underwent either one- or two-muscle surgery at our institution, for moderate hyperdeviation, due to presumed unilateral fourth nerve palsy, measuring 14 to 25 PD in straight ahead gaze at distance fixation. Six week and 1-year motor success was defined as zero vertical deviation or 1-4 PD undercorrection at distance, overcorrection as any reversal of hypertropia, and undercorrection as >4 PD...
July 4, 2017: American Journal of Ophthalmology
https://www.readbyqxmd.com/read/28681792/vertical-gaze-palsy-due-to-acute-bilateral-thalamic-infarct-without-midbrain-ischemia
#16
Shakya Bhattacharjee, Kher Lik Ng
No abstract text is available yet for this article.
July 2017: Neurology India
https://www.readbyqxmd.com/read/28681278/are-we-overlooking-masked-bilateral-congenital-superior-oblique-palsy-in-children-is-it-possible-to-diagnose-before-surgery
#17
Kadriye Erkan Turan, Hande Taylan Sekeroglu, Ali Sefik Sanac
PURPOSE: To describe the characteristics of children who had subsequent contralateral superior oblique underaction (SOUA) and inferior oblique overaction (IOOA) after unilateral inferior oblique weakening surgery and to identify suggestive clinical features for masked bilateral fourth nerve palsy. METHODS: The medical records of children who underwent unilateral inferior oblique tenotomy as a single procedure for unilateral superior oblique palsy were all reviewed...
July 5, 2017: International Ophthalmology
https://www.readbyqxmd.com/read/28661425/characterizing-computer-access-using-a-one-channel-eeg-wireless-sensor
#18
Alberto J Molina-Cantero, Jaime Guerrero-Cubero, Isabel M Gómez-González, Manuel Merino-Monge, Juan I Silva-Silva
This work studies the feasibility of using mental attention to access a computer. Brain activity was measured with an electrode placed at the Fp1 position and the reference on the left ear; seven normally developed people and three subjects with cerebral palsy (CP) took part in the experimentation. They were asked to keep their attention high and low for as long as possible during several trials. We recorded attention levels and power bands conveyed by the sensor, but only the first was used for feedback purposes...
June 29, 2017: Sensors
https://www.readbyqxmd.com/read/28634598/previously-unrecognized-behavioral-phenotype-in-gaucher-disease-type-3
#19
Magy Abdelwahab, Michael Potegal, Elsa G Shapiro, Igor Nestrasil
OBJECTIVE: To provide a comprehensive description of abnormal behaviors in patients with Gaucher disease type 3 (GD3) and relate these behaviors to demographic, neurodevelopmental, and neurologic characteristics. METHODS: Thirty-four Egyptian patients with GD3 (mean age of 7.9 years) were enrolled in the study. They were selected based on parent report and/or physician observation of one or more abnormal behaviors documented in 2 settings and by 2 different individuals and/or by video recording...
June 2017: Neurology. Genetics
https://www.readbyqxmd.com/read/28632466/neuropsychological-profiles-of-children-with-cerebral-palsy
#20
Kristine Stadskleiv, Reidun Jahnsen, Guro L Andersen, Stephen von Tetzchner
PURPOSE: To explore factors contributing to variability in cognitive functioning in children with cerebral palsy (CP). METHOD: A geographical cohort of 70 children with CP was assessed with tests of language comprehension, visual-spatial reasoning, attention, working memory, memory, and executive functioning. Mean age was 9;9 years (range 5;1-17;7), 54.3% were girls, and 50.0% had hemiplegic, 25.7% diplegic, 12.9% quadriplegic, and 11.4% dyskinetic CP. For the participants with severe motor impairments, assessments were adapted for gaze pointing...
February 21, 2017: Developmental Neurorehabilitation
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