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https://www.readbyqxmd.com/read/28432112/reduction-of-severe-visual-loss-and-complications-following-intra-arterial-chemotherapy-iac-for-refractory-retinoblastoma
#1
M Ashwin Reddy, Zishan Naeem, Catriona Duncan, Fergus Robertson, Jane Herod, Adam Rennie, Alki Liasis, Dorothy Ann Thompson, Mandeep Sagoo
BACKGROUND: Intra-arterial chemotherapy (IAC) for retinoblastoma has been documented as causing visual loss and ocular motility problems. A lack of safety data has precluded its acceptance in all centres. METHODS: Retrospective cohort study of patients with retinoblastoma from 2013 to 2015 who had a healthy foveola and relapsed following systemic chemotherapy. All required IAC. The correlation of complications with doses of melphalan +/- topotecan used and putative catheterisation complications was assessed...
April 21, 2017: British Journal of Ophthalmology
https://www.readbyqxmd.com/read/28410279/ocular-motor-manifestations-of-multiple-sclerosis
#2
Elodie Nerrant, Caroline Tilikete
BACKGROUND: Multiple sclerosis (MS) is a demyelinating disease of the central nervous system leading to disability, especially in young patients. Acute or chronic lesions of MS within the brainstem and the cerebellum frequently result in ocular motor disorders. EVIDENCE ACQUISITION: This review encompasses the spectrum of ocular motor disorders in patients with MS emphasizing prevalence, examination findings, diagnostic features, functional consequences, classification of MS course, and management of these disturbances of ocular motility...
April 13, 2017: Journal of Neuro-ophthalmology: the Official Journal of the North American Neuro-Ophthalmology Society
https://www.readbyqxmd.com/read/28389894/upper-fornix-approach-combined-with-a-superior-lateral-cantholysis-a-minimally-invasive-approach-to-the-superonasal-intraconal-space
#3
Ho-Seok Sa, Ji Won Seo, Sunah Kang
PURPOSE: To present a new minimally invasive approach to the deep superonasal orbit. METHODS: This retrospective study reviewed seven consecutive patients who underwent orbital surgery using an upper conjunctival fornix approach combined with a superior lateral cantholysis for tumors in the superonasal intraconal space. Charts were reviewed for demographic, radiological, clinical, and surgical data including surgical outcome and morbidities for each patient. RESULTS: Six benign tumors of the superonasal intraconal orbit were successfully exposed and removed using this approach, and one malignant tumor was biopsied for diagnosis...
April 7, 2017: Japanese Journal of Ophthalmology
https://www.readbyqxmd.com/read/28375653/an-innovative-method-of-ocular-prosthesis-fabrication-by-bio-cad-and-rapid-3-d-printing-technology-a-pilot-study
#4
Shahid Alam, M Sugavaneswaran, G Arumaikkannu, Bipasha Mukherjee
Ocular prosthesis is either a readymade stock shell or custom made prosthesis (CMP). Presently, there is no other technology available, which is either superior or even comparable to the conventional CMP. The present study was designed to fabricate ocular prosthesis using computer aided design (CAD) and rapid manufacturing (RM) technology and to compare it with custom made prosthesis (CMP). The ocular prosthesis prepared by CAD was compared with conventional CMP in terms of time taken for fabrication, weight, cosmesis, comfort, and motility...
April 4, 2017: Orbit
https://www.readbyqxmd.com/read/28367527/botulinum-toxin-injection-in-the-patients-with-duane-syndrome-type-1
#5
Ahmad Ameri, Farzad Farzbod, Fatemeh Bazvand, Arash Mirmohammadsadeghi, Mohammadreza Akbari, Faramarz Anvari, Simindokht Hosseini
PURPOSE: To evaluate the efficacy of botulinum toxin injection in the patients with type 1 Duane syndrome and identify the predictive factors for success. METHODS: Sixteen patients with esotropic type 1 Duane syndrome without history of ocular surgery were selected for this interventional case series. The botulinum toxin was injected in the medial rectus of all patients. Visual acuity, dry refraction, cyclo-refraction, ocular motility, and amount of deviation were measured...
March 2017: Journal of Current Ophthalmology
https://www.readbyqxmd.com/read/28360792/orbital-myositis-evaluating-five-new-cases-regarding-clinical-and-radiological-features
#6
Özlem Önder, Rıfat Reha Bilgin, Aslı Köşkderelioğlu, Muhteşem Gedizlioğlu
Orbital myositis (OM) is an inflammatory disorder of the extraocular muscles. The signs and symptoms of OM are periorbital pain, eyelid swelling and redness, restricted ocular motility, and strabismus. There are at least two major forms, described by Benedikt GH Schoser, a limited oligosymptomatic ocular myositis (LOOM), which is associated with conjunctival injection only, and severe exophthalmic ocular myositis (SEOM), which presents with additional ptosis, chemosis, and proptosis. We report the clinical and radiological features of five patients with OM who were recently followed in our clinic...
June 2016: Noro Psikiyatri Arsivi
https://www.readbyqxmd.com/read/28350678/ocular-morbidity-in-the-correction-of-orbital-hypertelorism-and-dystopia-a-15-year-experience
#7
Graeme E Glass, Kate A V Hon, Kemmy Schweibert, Richard Bowman, Barry M Jones, David J Dunaway, Jonathan A Britto
BACKGROUND: Complex surgery for appearance change is controversial. Correction of orbital hypertelorism risks diplopia and loss of stereopsis for aesthetic gain. The risk-to-benefit ratio remains ill-defined. The aim of this study was to define specific ocular morbidity following orbital translocation. METHODS: The authors compared stable preoperative and postoperative orthoptic indices (i.e., angle of strabismus, ocular motility, and acuity) for 23 consecutive patients who underwent orbital translocation between 2000 and 2015 and noted the requirement for corrective surgery...
April 2017: Plastic and Reconstructive Surgery
https://www.readbyqxmd.com/read/28336282/-management-of-upper-eyelid-retraction-associated-with-dysthyroid-orbitopathy-during-the-acute-inflammatory-phase-with-botulinum-toxin-type-a
#8
A Nava Castañeda, J L Tovilla Canales, L Garnica Hayashi, A Velasco Y Levy
PURPOSE: To evaluate the efficacy of transconjunctival botulinum toxin type A (BTX-A) in the treatment of upper eyelid retraction in the active inflammatory phase of dysthyroid orbitopathy, establish the ideal dose, and evaluate side effects. METHODS: This is a comparative, prospective study in patients with thyroid orbitopathy, conducted at the Conde Ophthalmology Institute in Valenciana, Mexico. The patients included had dysthyroid orbitopathy in the inflammatory phase, and they were treated with subconjunctival injection of botulinum toxin type A (BTX-A) in the upper eyelid...
April 2017: Journal Français D'ophtalmologie
https://www.readbyqxmd.com/read/28303385/after-effects-of-cerebellar-continuous-theta-burst-stimulation-on-reflexive-saccades-and-smooth-pursuit-in-humans
#9
Silvia Colnaghi, P Colagiorgio, S Ramat, E D'Angelo, G Koch, M Versino
The use of cerebellar repetitive transcranial magnetic stimulation has been attempted for perturbing reflexive and voluntary eye movements, but discrepancies are seen between the results of distinct studies possibly due to the different stimulation sites, intensities, and paradigms. We describe the after effects of 20 and 40 s continuous Theta Burst Stimulation (cTBS) as compared to sham stimulation, applied over the lateral cerebellar vermis and paravermis on Reflexive Saccades (RS) and Smooth Pursuit (SP) eye movements, recorded in the 30 min following stimulation...
March 16, 2017: Cerebellum
https://www.readbyqxmd.com/read/28302533/strabismus-measurements-in-adults-before-and-after-pupil-dilation
#10
Sean S Rivera, Michael S Lee, Scott Lunos, Jill S Anderson, Erick D Bothun
PURPOSE: To determine the effect of dilating drops on strabismus measurements in adults. DESIGN: Prospective cohort study METHODS: Patients age 18 and older with strabismus underwent a standard evaluation of ocular motility, stereopsis, and ocular alignment with alternate prism cover test by a certified orthoptist. After pupil dilation with 2.5% phenylephrine and 1% tropicamide, ocular alignment was re-measured in primary gaze at 6 meters, at 1/3 meter and at 1/3 meter with a +3...
March 13, 2017: American Journal of Ophthalmology
https://www.readbyqxmd.com/read/28299014/deep-orbital-dermoid-cyst-bulging-into-the-superior-orbital-fissure-clinical-presentation-and-management
#11
Ravinder Kumar, Kapil Vyas, Gagan Jaiswal, Abhishek Bhargava, Jyoti Kundu
PURPOSE: To present a case of deep orbital dermoid cyst with emphasis on clinical presentation, imaging spectrum, differential diagnosis and management. CASE REPORT: A 28-year-old female was referred to our hospital with chief complaint of drooping of right eyelid and progressive headache. Ocular motility, visual acuity and fundus examination were normal. computed tomography (CT) and magnetic resonance imaging (MRI) revealed a well-defined, intraosseous deep orbital dermoid cyst (5...
January 2017: Journal of Ophthalmic & Vision Research
https://www.readbyqxmd.com/read/28296806/new-observations-regarding-the-retinopathy-of-genetically-confirmed-kearns-sayre-syndrome
#12
Igor Kozak, Darren T Oystreck, Khaled K Abu-Amero, Sawsan R Nowilaty, Hisham Alkhalidi, Sahar M Elkhamary, Sarar Mohamed, Muddathir H A Hamad, Mustafa A Salih, Emma L Blakely, Robert W Taylor, Thomas M Bosley
PURPOSE: To report novel retinal findings in Kearns-Sayre syndrome and correlate degree of retinopathy with other clinical findings. METHODS: Observational case series of patients from Saudi Arabia with retinal and neuroophthalmologic examinations, medical chart review, and mitochondrial genetic evaluation. RESULTS: The three unrelated patients had progressive external ophthalmoplegia and pigmentary retinopathy bilaterally. Muscle biopsy in two of the cases revealed mitochondrial myopathy...
December 19, 2016: Retinal Cases & Brief Reports
https://www.readbyqxmd.com/read/28293536/early-onset-bilateral-juvenile-myasthenia-gravis-masquerading-as-simple-congenital-ptosis
#13
Md Shahid Alam, Pratheeba Devi Nivean
Myasthenia gravis is an autoimmune disorder affecting the neuromuscular junction. Ocular myasthenia gravis presents as ptosis with extraocular motility restriction and is prone to be misdiagnosed as third nerve palsy or congenital or aponeurotic ptosis. Juvenile ocular myasthenia gravis in very young children is difficult to diagnose and can be easily labeled as a case of congenital ptosis, the more so when the condition is bilateral. We present a case of a two-year-old child who presented with bilateral ptosis and was diagnosed as a case of simple congenital ptosis elsewhere with the advice to undergo tarsofrontalis sling surgery...
2017: GMS Ophthalmology Cases
https://www.readbyqxmd.com/read/28291193/-surgical-rehabilitation-of-patients-with-thyroid-eye-disease-systematic-approach
#14
S E Avetisov, Ya O Grusha, D S Ismailova, P A Kochetkov, S S Danilov, N Yu Sviridenko
AIM: to analyze the results of surgical treatment of patients with thyroid eye disease (TED), including the type of surgery, indications, and outcomes. MATERIAL AND METHODS: Hundred thirty-nine patients with TED (112 females, 27 males) aged 45.8±13.6 years. RESULTS: Bony orbital decompression was performed in 91 patients (128 orbits). After the surgery, visual acuity increased from 0.84±0.47 up to 0.94±0.32 (р<0.05), exophthalmos got reduced by the average of 3...
2017: Vestnik Oftalmologii
https://www.readbyqxmd.com/read/28286306/a-controlled-study-of-the-role-of-cryopreserved-amniotic-membrane-transplant-during-strabismus-reoperations
#15
Rehab Rashad Kassem, Ahmed Mostafa Kamal, Randa Mohamed Abdel-Moneim El-Mofty, Hala Mostafa Elhilali
PURPOSE: To evaluate the effects of using cryopreserved human amniotic membrane (AM) transplant during strabismus reoperations. METHODS: A total of 30 patients with persistent strabismus were included in this prospective study. Patients were divided into two groups of 15 patients each. The AM group underwent strabismus reoperation with wrapping of the muscles with cryopreserved amniotic membrane. Controls underwent strabismus reoperation without an AM wrap. Final follow-up visit was scheduled between 3 and 12 months postoperatively...
April 2017: Journal of AAPOS: the Official Publication of the American Association for Pediatric Ophthalmology and Strabismus
https://www.readbyqxmd.com/read/28251554/a-review-of-minimally-invasive-strabismus-surgery-miss-is-this-the-way-forward
#16
REVIEW
Ioannis Asproudis, Nikolaos Kozeis, Andreas Katsanos, Saurabh Jain, Paris G Tranos, Anastasios-Georgios P Konstas
Minimally invasive surgery is rapidly becoming the norm in medicine, as it often leads to better outcomes and earlier rehabilitation. This article reviews the principles and different techniques employed to perform minimally invasive strabismus surgery (MISS). In these techniques, strabismus surgery is performed through keyhole openings, thus reducing the risk of postoperative corneal complications, minimizing postoperative discomfort, and better preserving muscle function. MISS can be used to perform all types of strabismus surgery, namely rectus muscle recessions, resections, plications, reoperations, retroequatorial myopexy, transpositions, oblique muscle recessions, or plications even in the presence of limited motility...
April 2017: Advances in Therapy
https://www.readbyqxmd.com/read/28237148/slipped-extraocular-muscles-characteristics-and-surgical-outcomes
#17
Christiane Al-Haddad, Maamoun Abdul Fattah
OBJECTIVE: To study the frequency and characteristics of slipped extraocular muscles after strabismus surgery and report the postoperative outcomes longitudinally. DESIGN: Retrospective chart review. PARTICIPANTS: Electronic medical records of 493 patients who underwent strabismus surgery and were found to have a slipped muscle intraoperatively were reviewed. METHODS: Records were retrieved and operative reports were screened for the presence of slipped muscles...
February 2017: Canadian Journal of Ophthalmology. Journal Canadien D'ophtalmologie
https://www.readbyqxmd.com/read/28169905/reconstruction-of-large-orbital-posterior-floor-wall-fracture-considering-orbital-floor-slope-using-endoscope
#18
Jinhwan Park, Jungah Huh, Joonsik Lee, Minwook Chang, Hwa Lee, Minsoo Park, Sehyun Baek
PURPOSE: Reconstruction of a large orbital fracture extending to the posterior wall of the maxillary sinus is difficult and challenging. In this study, the authors present transconjunctival or transcaruncular approach using endoscopy and layered porous polyethylene barrier sheets to manage large orbital floor wall fracture. METHODS: A retrospective review of all patients who underwent reconstruction of large orbital floor wall fractures between June 2009 and July 2015 was conducted...
February 6, 2017: Journal of Craniofacial Surgery
https://www.readbyqxmd.com/read/28165827/clinical-characteristics-treatment-and-outcome-of-trochleitis
#19
Elena Jarrín, Ángel García-García, Francisco J Hurtado-Ceña, José M Rodríguez-Sánchez
BACKGROUND AND PURPOSE: To study the clinical characteristics, treatment options, and outcome of patients with trochleitis in our population. METHODS: Retrospective review of 59 patients diagnosed with trochleitis in the Ramon y Cajal Hospital Emergency Service between 2003 and 2010. Demographic data and trochleitis features were described. The relationship between outcome and treatment options was analyzed by SPSS. RESULTS: The estimated prevalence rate of trochleitis in our area was 12 per 100,000...
March 2017: Strabismus
https://www.readbyqxmd.com/read/28145940/using-the-endoscopic-transconjunctival-and-transcaruncular-approach-to-repair-combined-orbital-floor-and-medial-wall-blowout-fractures
#20
Minwook Chang, Seong Won Yang, Jin-Hwan Park, Joonsik Lee, Hwa Lee, Min Soo Park, Sehyun Baek
PURPOSE: To demonstrate the effectiveness of the endoscopic transcaruncular and transconjunctival approach in the repair of combined medial and inferior orbital wall fractures. METHODS: A retrospective chart review was conducted on 160 patients with combined medial and inferior orbital wall fractures. All patients underwent surgery via an endoscopic transcaruncular and transconjunctival approach without lateral canthotomy, performed by a single surgeon. Porous polyethylene sheets (1...
January 31, 2017: Journal of Craniofacial Surgery
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