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https://www.readbyqxmd.com/read/29655447/ocular-myasthenia
#1
REVIEW
Mohammed Al-Haidar, Michael Benatar, Henry J Kaminski
Ocular myasthenia is a form of myasthenia gravis in which weakness is restricted to the ocular muscles and may produce significant visual disability. Patients present with fluctuating ptosis, diplopia, or a combination of both. Examination may show any type of ocular motility deficit ranging from isolated muscle palsy to complete ophthalmoplegia. Cogan lid twitch, enhanced ptosis, peek sign, and saccadic fatigue are specific examination findings that support the clinical diagnosis of myasthenia gravis. Confirmation of the diagnosis is challenging with autoantibody serology, and repetitive nerve stimulation studies are often negative...
May 2018: Neurologic Clinics
https://www.readbyqxmd.com/read/29600186/symptomatic-accommodative-and-binocular-dysfunctions-from-the-use-of-flat-panel-displays
#2
Esteban Porcar, Juan Carlos Montalt, Álvaro M Pons, Enrique España-Gregori
AIM: To determine the presence of symptomatic accommodative and non-strabismic binocular dysfunctions (ANS BD) in a non-presbyopic population of video display unit (VDU) users with flat-panel displays. METHODS: One hundred and one VDU users, aged between 20 to 34y, initially participated in the study. This study excluded contact-lens wearers and subjects who had undergone refractive surgery or had any systemic or ocular disease. First, subjects were asked about the type and nature of eye symptoms they experienced during VDU use...
2018: International Journal of Ophthalmology
https://www.readbyqxmd.com/read/29600179/safety-and-efficacy-of-posterior-sub-tenon-s-carboplatin-injection-versus-intravitreal-melphalan-therapy-in-the-management-of-retinoblastoma-with-secondary-vitreous-seeds
#3
Azza Mohamed Ahmed Said, Mohamed Gamil Aly, Hazem Omar Rashed, Anwaar Mahmoud Rady
AIM: To evaluate the safety and efficacy of posterior sub-Tenon's carboplatin injection compared to intravitreal melphalan injection in the management of retinoblastoma (RB) with secondary vitreous seeds. The outcome measures were vitreous seeds regression, need for other treatment modalities to achieve ocular salvage and treatment side effects. METHODS: A prospective interventional comparative nonrandomized study included RB eyes developed secondary vitreous seeds during the period of follow up...
2018: International Journal of Ophthalmology
https://www.readbyqxmd.com/read/29590687/comparative-study-of-the-usefulness-of-the-binocular-spot-vision-screener-autorefractor-in-the-detection-of-childhood-visual-disorders
#4
Nathalie Voide, Nicole Hoeckele, Pierre-François Kaeser
BACKGROUND: The Spot Vision Screener (SVS) is designed to detect significant ametropia, anisometropia, and strabismus in non-dilated eyes. This study evaluates the efficacy of the SVS in paediatric visual screening. PATIENTS AND METHODS: All children screened during the paediatric visual screening day in Lausanne in 2016 were evaluated with the SVS, conventional monocular autorefractors, and clinical orthoptic examination. Recommendations for a further eye examination of the SVS were compared with those issued from traditional clinical screenings (monocular refraction and orthoptic examination)...
March 28, 2018: Klinische Monatsblätter Für Augenheilkunde
https://www.readbyqxmd.com/read/29582260/orbital-apex-syndrome-secondary-to-optic-nerve-cysticercosis
#5
Pratik Chaugule, D Ravi Varma, Preeti Patil Chhablani
A 22-year-old male presented to us with complaints of sudden painful loss of vision in left eye 10 days ago along with inward deviation of the left eye. Best-corrected visual acuity (BCVA) in right eye was 20/20 and 20/50 in left eye. Left eye showed limitation of abduction, a relative afferent pupillary defect, normal anterior segment with optic disc oedema. Contrast-enhanced MRI of the brain and orbit showed thickening of left optic nerve along with a cystic lesion near the orbital apex with a central iso- to hyperintense spot resembling a scolex...
March 26, 2018: International Ophthalmology
https://www.readbyqxmd.com/read/29582258/strabismus-surgery-for-diplopia-in-chronic-progressive-external-ophthalmoplegia
#6
Klio I Chatzistefanou, Dimitrios Brouzas, Ioannis Asproudis, Efthimia Tsina, Konstantinos D Droutsas, Chryssanthi Koutsandrea
BACKGROUND: To report midterm outcomes of strabismus strategy for management of diplopia in chronic progressive external ophthalmoplegia and specific surgical planning rationale. DESIGN: Retrospective interventional case series. RESULTS: Two patients, a 26-year-old male and a 36-year-old female, diagnosed with chronic progressive external ophthalmoplegia presented with blepharoptosis and intermittent diplopia. Ocular motility examination was significant for bilateral profound impairment of adduction with relative preservation of abduction, infraduction and elevation...
March 26, 2018: International Ophthalmology
https://www.readbyqxmd.com/read/29547465/orbital-plates-and-screws-causing-globe-fixation-a-rare-and-delayed-complication-of-craniomaxillofacial-surgery
#7
Varun Chandra, Danielle Buck, Rahul Chakrabarti, Alan McNab
A 24-year-old woman presented with a 1-year history of gradually increasing pain on eye movements, worse on the right. She had a significant background of undergoing intracranial correction of orbital hypertelorism with internal fixation of the lateral orbital rims at the age of 6 years. Imaging was consistent with bilateral metallic foreign bodies from both lateral orbital rims protruding into the globes. The patient underwent removal of bilateral plates and screws, with a significant improvement of symptoms and ocular motility postoperatively...
March 14, 2018: Ophthalmic Plastic and Reconstructive Surgery
https://www.readbyqxmd.com/read/29538190/low-grade-malignant-fibrous-histiocytoma-originating-from-the-medial-rectus-muscle
#8
Jianhua Yan
PURPOSE: Fibrous histiocytomas (FHs) involving the orbit are uncommon. To our knowledge, here the authors report the first patient with an orbital low-grade malignant FH originating from the medial rectus muscle. METHODS: A clinical report relating clinical features as well as imaging and histopathologic findings is presented. RESULTS: A 26-year-old female presented with a left eye proptosis that had been present for 4 months. A small left exotropia was observed and ocular motility evaluation revealed a -3 adduction and -1 abduction of the left eye...
March 13, 2018: Journal of Craniofacial Surgery
https://www.readbyqxmd.com/read/29505103/interventions-for-eye-movement-disorders-due-to-acquired-brain-injury
#9
REVIEW
Fiona J Rowe, Kerry Hanna, Jennifer R Evans, Carmel P Noonan, Marta Garcia-Finana, Caroline S Dodridge, Claire Howard, Kathryn A Jarvis, Sonia L MacDiarmid, Tallat Maan, Lorraine North, Helen Rodgers
BACKGROUND: Acquired brain injury can cause eye movement disorders which may include: strabismus, gaze deficits and nystagmus, causing visual symptoms of double, blurred or 'juddery' vision and reading difficulties. A wide range of interventions exist that have potential to alleviate or ameliorate these symptoms. There is a need to evaluate the effectiveness of these interventions and the timing of their implementation. OBJECTIVES: We aimed to assess the effectiveness of any intervention and determine the effect of timing of intervention in the treatment of strabismus, gaze deficits and nystagmus due to acquired brain injury...
March 5, 2018: Cochrane Database of Systematic Reviews
https://www.readbyqxmd.com/read/29467810/brown-syndrome-following-upper-eyelid-ptosis-repair
#10
Yao Wang, Timothy J McCulley, Jefferson J Doyle, Jessica Chang, Michael S Lee, Collin M McClelland
Brown syndrome is characterised by impaired supraduction worse in adduction due to a restricted superior oblique tendon passing through the trochlea. A few reports have previously described Brown syndrome after upper eyelid surgery, including blepharoplasty and ptosis repair. The authors describe two additional cases of Brown syndrome following ptosis repair. The first case is a 65-year-old woman with new-onset vertical binocular diplopia following bilateral levator advancement surgery. Ocular motility examination demonstrated moderate impairment of elevation in adduction...
February 2018: Neuro-ophthalmology
https://www.readbyqxmd.com/read/29427106/the-neuropathology-of-spinocerebellar-ataxia-type-3-machado-joseph-disease
#11
Arnulf H Koeppen
Spinocerebellar ataxia type 3 (SCA-3)/Machado-Joseph disease (MJD), the most common autosomal dominant ataxia, affects many regions of the brain and spinal cord. Similar to SCA-1, SCA-2, SCA-6, SCA-7, and SCA-17, the mutation consists of a pathogenic translated cytosine-adenine-guanine (CAG) trinucleotide repeat expansion. Almost invariably, the substantia nigra and the dentate nucleus of the cerebellum bear the brunt of the disease, and these lesions account for the Parkinsonian and ataxic phenotypes. Lesions of motor nuclei in the brain stem cause the complex disturbance of ocular motility and weakness of the tongue...
2018: Advances in Experimental Medicine and Biology
https://www.readbyqxmd.com/read/29419638/permanent-versus-bioresorbable-implants-in-orbital-floor-blowout-fractures
#12
Sophia Seen, Stephanie Ming Young, Shao Jin Teo, Stephanie S Lang, Shantha Amrith, Thiam-Chye Lim, Gangadhara Sundar
PURPOSE: To compare the outcomes of bioresorbable and permanent implants in the reconstruction of isolated orbital floor blowout fractures. METHODS: Retrospective series of all patients who had orbital floor fracture repair in a single tertiary trauma center from January 2005 to December 2014. The authors reviewed the case notes and CT scans of patients with orbital floor fracture repair with either bioresorbable or permanent implants. Main outcome measures were enophthalmos, diplopia, and ocular motility restriction 1...
February 6, 2018: Ophthalmic Plastic and Reconstructive Surgery
https://www.readbyqxmd.com/read/29396245/combined-immunosuppression-and-radiotherapy-in-thyroid-eye-disease-cirted-a-multicentre-2-%C3%A3-2-factorial-double-blind-randomised-controlled-trial
#13
Rathie Rajendram, Peter N Taylor, Victoria J Wilson, Nicola Harris, Olivia C Morris, Marjorie Tomlinson, Sue Yarrow, Helen Garrott, Helen M Herbert, Andrew D Dick, Anne Cook, Rao Gattamaneni, Rajni Jain, Jane Olver, Steven J Hurel, Fion Bremner, Suzannah R Drummond, Ewan Kemp, Diana M Ritchie, Nichola Rumsey, Daniel Morris, Carol Lane, Nachi Palaniappan, Chunhei Li, Julie Pell, Robert Hills, Daniel G Ezra, Mike J Potts, Sue Jackson, Geoffrey E Rose, Nicholas Plowman, Catey Bunce, Jimmy M Uddin, Richard W J Lee, Colin M Dayan
BACKGROUND: Standard treatment for thyroid eye disease is with systemic corticosteroids. We aimed to establish whether orbital radiotherapy or antiproliferative immunosuppression would confer any additional benefit. METHODS: CIRTED was a multicentre, double-blind, randomised controlled trial with a 2 × 2 factorial design done at six centres in the UK. Adults with active moderate-to-severe thyroid eye disease associated with proptosis or ocular motility restriction were recruited to the trial...
April 2018: Lancet Diabetes & Endocrinology
https://www.readbyqxmd.com/read/29386493/-a-case-of-wernicke-encephalopathy-with-hypoacusia-and-mr-high-intensity-of-the-inferior-colliculi-that-normalized-after-thiamine-administration
#14
Takuma Nakamura, Keisuke Imai, Masashi Hamanaka, Hidekazu Yamazaki, Takehiro Yamada, Toshiki Mizuno
A 61-year-old man was admitted to our institution with progressive hypoacusia, double vision, and lightheadedness. Neurological examination on day 6 of his illness showed severe hypoacusia, mild confusion, ocular motility disorder, truncal ataxia and absence of a deep tendon reflex. MRI fluid-attenuated inversion recovery imaging revealed symmetrical high intensities in the tectum of the midbrain, involving the bilateral inferior colliculi and the bilateral medial thalami, which suggested Wernicke encephalopathy (WE)...
January 31, 2018: Rinshō Shinkeigaku, Clinical Neurology
https://www.readbyqxmd.com/read/29373868/-chronic-progressive-external-ophthalmoplegia-ptosis-problems-with-diagnostics-and-treatment
#15
Markus J Pfeiffer
Ptosis is often the first symptom of chronic progressive external ophthalmoplegia (CPEO), a rare muscle disorder. As the disease progresses, it can lead to ocular motility defects. Ptosis is present in the early stages of the disease and can be corrected by levator surgery. Due to the rarity of CPEO (< 1% of ptosis patients), further diagnostic steps with muscle biopsy and genetic analysis of mitochondrial DNA are usually not considered in the early phase. Intraoperative abnormal observations during ptosis surgery and postoperative motility problems are signs of CPEO...
January 2018: Klinische Monatsblätter Für Augenheilkunde
https://www.readbyqxmd.com/read/29369530/ophthalmological-data-on-4-5-to-7-year-old-danish-children
#16
Lisbeth Sandfeld, Hanne Weihrauch, Gitte Tubaek, Panteleimon Mortzos
PURPOSE: To report normative data on visual acuity (VA) for near and distance, refraction, ocular alignment, ocular motility and stereo acuity in a cohort of children aged 4.5-7 years. METHODS: A total of 950 children with normal development from the municipality of Roskilde, Denmark, were invited to participate in an ophthalmic cross-sectional population-based survey, of which 445 children in the age of 54-87 months participated with a complete ocular examination including cycloplegia...
January 25, 2018: Acta Ophthalmologica
https://www.readbyqxmd.com/read/29369153/deep-orbital-sub-q-hyaluronic-acid-filler-injection-for-enophthalmic-sighted-eyes-in-parry-romberg-syndrome
#17
Ilan Feldman, Vladimir A Sheptulin, Yaroslav O Grusha, Raman Malhotra
PURPOSE: The authors present a consecutive series of deep orbital Sub-Q injections to treat enophthalmic sighted eyes in Parry-Romberg syndrome patients. METHODS: Retrospective, interventional case series in 2 centers. Data were collected on patient demographics, Parry-Romberg syndrome onset age, previous orbital and eyelid surgeries, diplopia, ocular movement restriction before and after the injection, number of injections, interval between injections, indication for any top-up or dissolution of filler, and any other complications...
January 23, 2018: Ophthalmic Plastic and Reconstructive Surgery
https://www.readbyqxmd.com/read/29344068/clinical-versus-evidence-based-rehabilitation-options-for-post-stroke-visual-impairment
#18
REVIEW
K L Hanna, F J Rowe
The aim of this study was to identify which treatments for post-stroke visual impairment have a supportive evidence base, and which are being used in practice without supportive evidence. A systematic review of the literature reporting on the available treatment options was compared against the visual treatments used in the Vision In Stroke (VIS) study. Treatments were identified for visual field, visual neglect, visual perception and ocular motility disorders. Visual scanning therapies for hemianopia and neglect have an established evidence base...
December 2017: Neuro-ophthalmology
https://www.readbyqxmd.com/read/29325382/-knapp-procedure-and-modified-knapp-procedure-with-foster-suture-for-the-treatment-of-double-elevator-palsy
#19
Y P Li, W Zhang, J Ding, H Z Ma, K X Zhao
Objective: To investigate the efficacy of Knapp procedure and modified Knapp procedure with Foster suture in the treatment of double elevator palsy(DEP). Methods: Retrospective study. Twenty-two patients with congenital DEP were underwent Knapp procedure ( n= 15) and modified Knapp procedure( n= 7). The clinical data were retrospectively analyzed, including the preoperative and postoperative vertical deviation in the primary position, ocular motility, and binocular vision. Results: The average vertical deviation in the primary position was (34...
December 11, 2017: [Zhonghua Yan Ke za Zhi] Chinese Journal of Ophthalmology
https://www.readbyqxmd.com/read/29320823/first-blindness-cases-of-horses-infected-with-setaria-digitata-nematoda-filarioidea-in-the-republic-of-korea
#20
Jihun Shin, Kyu-Sung Ahn, Guk-Hyun Suh, Ha-Jung Kim, Hak-Sub Jeong, Byung-Su Kim, Eunsang Choi, Sung-Shik Shin
Ocular setariases of cattle were reported but those of equine hosts have never been reported in the Republic of Korea (Korea). We found motile worms in the aqueous humor of 15 horses (Equus spp.) from 12 localities in southern parts of Korea between January 2004 and November 2017. After the affected animals were properly restrained under sedation and local anesthesia, 10 ml disposable syringe with a 16-gauge needle was inserted into the anterior chamber of the affected eye to successfully remove the parasites...
December 2017: Korean Journal of Parasitology
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