keyword
https://read.qxmd.com/read/35530507/the-gut-microbiota-in-liver-transplantation-recipients-during-the-perioperative-period
#21
JOURNAL ARTICLE
Zhiyong Lai, Zongkun Chen, Anhong Zhang, Zhiqiang Niu, Meng Cheng, Chenda Huo, Jun Xu
Background: Chronic liver disease is a global problem, and an increasing number of patients receive a liver transplant yearly. The characteristics of intestinal microbial communities may be affected by changes in the pathophysiology of patients during the perioperative. Methods: We studied gut fecal microbial community signatures in 37 Chinese adults using 16S rRNA sequencing targeting V3-V4 hypervariable regions, with a total of 69 fecal samples. We analyzed the Alpha and Beta diversities of various groups...
2022: Frontiers in Physiology
https://read.qxmd.com/read/35357106/perioperative-enteral-immunonutrition-with-probiotics-favors-the-nutritional-inflammatory-and-functional-statuses-in-digestive-system-surgery
#22
JOURNAL ARTICLE
Zhen Huang, Yi Wang
BACKGROUND AND OBJECTIVES: This study aimed to evaluate the effects of enteral immunonutrition (EIN) on the nutritional status of patients during the perioperative period of digestive system surgery. METHODS AND STUDY DESIGN: The clinical data of 102 patients who underwent gastrointestinal surgery between August 2017 and February 2021 were retrospectively analyzed. According to the nutritional support regimen, the patients were divided into an enteral nutrition (EN) group (50 patients) and an EIN group (52 patients)...
March 2022: Asia Pacific Journal of Clinical Nutrition
https://read.qxmd.com/read/35341415/probiotics-improve-postoperative-adaptive-immunity-in-colorectal-cancer-patients-a-systematic-review-and-meta-analysis
#23
JOURNAL ARTICLE
Jie Chen, Huamin Liang, Jiaying Lu, Yanping He, Renxu Lai
There is no consensus on the effect of the probiotics on postoperative adaptive immunity in patients undergoing surgical resection for CRC. We aimed to systematically evaluate the effect of probiotics on postoperative adaptive immunity in perioperative CRC patients. The main end points were postoperative serum IgG, IgA, IgM, CD4+ T-cells, CD8+ T-cells and CD4+ -to-CD8+ ratio. Meta-analysis was performed with a fixed or random effects model. We included six randomized controlled trials (RCTs) with 492 perioperative CRC patients...
2022: Nutrition and Cancer
https://read.qxmd.com/read/35091321/effect-of-perioperative-probiotic-supplements-on-postoperative-short-term-outcomes-in-gastric-cancer-patients-receiving-neoadjuvant-chemotherapy-a-double-blind-randomized-controlled-trial
#24
JOURNAL ARTICLE
Gan Liu, Shougen Cao, Xiaodong Liu, Zequn Li, Yulong Tian, Xingqi Zhang, Hao Zhong, Yanbing Zhou
OBJECTIVES: Surgery can significantly improve the prognosis of patients with gastric cancer. However, some patients are at a later stage at diagnosis and need to receive neoadjuvant chemotherapy (NACT). Previous studies have shown that NACT may lead to more postoperative complications. Probiotics have the potential to reduce postoperative complications and infections, but no similar clinical trials have been conducted in patients with gastric cancer receiving NACT. The aim of this study was to investigate the effect of probiotics on postoperative infections and other short-term outcomes in patients with gastric cancer receiving NACT...
April 2022: Nutrition
https://read.qxmd.com/read/35014851/-espen-guideline-clinical-nutrition-in-inflammatory-bowel-disease
#25
JOURNAL ARTICLE
Stephan C Bischoff, Johanna Escher, Xavier Hébuterne, Stanisław Kłęk, Zeljko Krznaric, Stéphane Schneider, Raanan Shamir, Kalina Stardelova, Nicolette Wierdsma, Anthony E Wiskin, Alastair Forbes, Miguel Montoro, Rosa Burgos Peláez
INTRODUCTION: the ESPEN guideline offers a multidisciplinary focus on clinical nutrition in inflammatory bowel disease (IBD). METHODOLOGY: the guideline is based on a extensive systematic review of the literature, but relies on expert opinion when objective data are lacking or inconclusive. The conclusions and 64 recommendations have been subject to full peer review and a Delphi process, in which uniformly positive responses (agree or strongly agree) were required...
January 11, 2022: Nutrición Hospitalaria: Organo Oficial de la Sociedad Española de Nutrición Parenteral y Enteral
https://read.qxmd.com/read/34940074/probiotics-evaluation-in-oncological-surgery-a-systematic-review-of-36-randomized-controlled-trials-assessing-21-diverse-formulations
#26
REVIEW
Elise Cogo, Mohamed Elsayed, Vivian Liang, Kieran Cooley, Christilynn Guerin, Athanasios Psihogios, Peter Papadogianis
BACKGROUND: Objectives were to evaluate probiotics safety and efficacy in oncological surgery. METHODS: Systematic review methodology guided by Cochrane, PRISMA, SWiM, and CIOMS. Protocol registered on PROSPERO (CRD42018086168). RESULTS: 36 RCTs (on 3305 participants) and 6 nonrandomized/observational studies were included, mainly on digestive system cancers. There was evidence of a beneficial effect on preventing infections, with 70% of RCTs' (21/30) direction of effect favoring probiotics...
December 7, 2021: Current Oncology
https://read.qxmd.com/read/34897739/case-presentation-and-panel-discussion-nutrition-issues-in-cancer
#27
JOURNAL ARTICLE
Manpreet S Mundi, Jeffrey I Mechanick, Jayshil J Patel, Alessandro Laviano, Robert G Martindale, Teresa A Zimmers
Advances in treatment of malignancy including novel pharmacologic therapies and surgical interventions has led to significant improvement in survival. As cancer becomes a chronic disease, nutrition interventions play an increasingly important role in short- and long-term outcomes. The current manuscript presents a case of a 66-year-old male with new diagnosis of pancreatic cancer diagnosed incidentally in the setting of COVID-19. Expert panelists in the field of nutrition discuss optimal strategies for diagnosis of malnutrition along with preoperative, perioperative, and postoperative optimization of nutrition...
November 2021: JPEN. Journal of Parenteral and Enteral Nutrition
https://read.qxmd.com/read/34485364/effects-of-perioperative-probiotics-and-synbiotics-on-pancreaticoduodenectomy-patients-a-meta-analysis-of-randomized-controlled-trials
#28
JOURNAL ARTICLE
Gang Tang, Linyu Zhang, Jie Tao, Zhengqiang Wei
Post-pancreaticoduodenectomy infections cause mortality, morbidity, and prolonged antibiotic use. Probiotics or synbiotics may be advantageous for preventing postoperative infections, but their benefits on pancreaticoduodenectomy outcomes are controversial. This study evaluated the efficacy of probiotics and synbiotics in pancreaticoduodenectomy. The Embase, Web of Science, PubMed, and Cochrane Library databases were comprehensively searched for randomized controlled trials (RCTs) that evaluated the effects of probiotics or synbiotics on pancreaticoduodenectomy as of April 16, 2021...
2021: Frontiers in Nutrition
https://read.qxmd.com/read/34173254/effects-of-oral-probiotics-administration-on-the-expression-of-transforming-growth-factor-%C3%AE-and-the-proinflammatory-cytokines-interleukin-6-interleukin-17-and-tumor-necrosis-factor-%C3%AE-in-skin-wounds-in-rats
#29
JOURNAL ARTICLE
Eliane Tagliari, Letícia Fuganti Campos, Thais Andrade Costa Casagrande, Taise Fuchs, Lúcia de Noronha, Antonio Carlos L Campos
BACKGROUND: Cytokines and growth factors play key roles during the tissue repair process. We aim to evaluate the effect of perioperative oral of probiotics, on the healing process in skin wound in rats, by histological aspects, and by the expression of TGF-β, and the pro-inflammatory cytokines IL6, IL7, and TNF-α. METHODS: 72 adult male Wistar rats were split into two groups control (n = 36) and probiotic group (n = 36). Each group was subdivided into three subgroups with 12 animals each according to euthanasia day: 3rd, 7th, and 10th postoperative(PO) day...
March 2022: JPEN. Journal of Parenteral and Enteral Nutrition
https://read.qxmd.com/read/34061274/probiotic-related-bacteremia-after-major-hepatectomy-for-biliary-cancer-a-report-of-two-cases
#30
JOURNAL ARTICLE
Mitsuhiro Shimura, Masamichi Mizuma, Kei Nakagawa, Shuichi Aoki, Takayuki Miura, Tatsuyuki Takadate, Kyohei Ariake, Shimpei Maeda, Kei Kawaguchi, Kunihiro Masuda, Masaharu Ishida, Hideo Ohtsuka, Takanori Morikawa, Takashi Kamei, Michiaki Unno
BACKGROUND: Probiotics have been reported to be beneficial for the prevention of postoperative complications and are often used during the perioperative period. Among the probiotic-related adverse events, bacteremia is rare. Here, we report two cases of probiotic-related bacteremia after major hepatectomy for biliary cancer. CASE PRESENTATION 1: A 74-year-old man was referred to our hospital to be treated for gallbladder cancer. Neoadjuvant chemotherapy, two courses of gemcitabine plus S-1 combination therapy, was administered...
June 1, 2021: Surgical Case Reports
https://read.qxmd.com/read/33947121/nanoceutical-adjuvants-as-wound-healing-material-precepts-and-prospects
#31
REVIEW
Kaushita Banerjee, Radha Madhyastha, Yuichi Nakajima, Masugi Maruyama, Harishkumar Madhyastha
Dermal wound healing describes the progressive repair and recalcitrant mechanism of 12 damaged skin, and eventually, reformatting and reshaping the skin. Many probiotics, nutritional supplements, metal nanoparticles, composites, skin constructs, polymers, and so forth have been associated with the improved healing process of wounds. The exact mechanism of material-cellular interaction is a point of immense importance, particularly in pathological conditions such as diabetes. Bioengineered alternative agents will likely continue to dominate the outpatient and perioperative management of chronic, recalcitrant wounds as new products continue to cut costs and improve the wound healing process...
April 29, 2021: International Journal of Molecular Sciences
https://read.qxmd.com/read/33935619/urinary-tract-infection-in-women
#32
REVIEW
Krzysztof Czajkowski, Magdalena Broś-Konopielko, Justyna Teliga-Czajkowska
Urinary tract infection (UTI) is one of the most common infections afflicting women. UTI often accompanies vaginal infections and is frequently caused by pathogens originating in the digestive tract. The paper discusses the prevalence of UTI in various patient populations, including postmenopausal, pregnant, diabetic, epileptic, and perioperative female patients. Current UTI treatment and prevention guidelines both for primary and recurring UTIs were reviewed. Antibiotic treatment duration should be minimized, with the exact dosage and time schedule depending on the type of infection...
April 2021: Menopause Review
https://read.qxmd.com/read/33922897/the-effect-of-perioperative-administration-of-probiotics-on-colorectal-cancer-surgery-outcomes
#33
REVIEW
Louise Pitsillides, Gianluca Pellino, Paris Tekkis, Christos Kontovounisios
The perioperative care of colorectal cancer (CRC) patients includes antibiotics. Although antibiotics do provide a certain protection against infections, they do not eliminate them completely, and they do carry risks of microbial resistance and disruption of the microbiome. Probiotics can maintain the microbiome's balance postoperatively by maintaining intestinal mucosal integrity and reducing bacterial translocation (BT). This review aims to assess the role of probiotics in the perioperative management of CRC patients...
April 25, 2021: Nutrients
https://read.qxmd.com/read/33692578/effects-of-a-perioperative-antibiotic-and-veterinary-probiotic-on-fecal-dysbiosis-index-in-dogs
#34
JOURNAL ARTICLE
Brittany Lucchetti, Selena L Lane, Amie Koenig, Jennifer Good, Jan S Suchodolski, Benjamin M Brainard
Although widely used, the effects of perioperative antibiotics on the gastrointestinal microbiome are still being researched. The role of probiotics to ameliorate adverse effects of perioperative antibiotics is unclear. The dysbiosis index (DI), based on a quantitative polymerase chain reaction (qPCR) technique, is used to assess gastrointestinal health. The DI in dogs receiving perioperative antibiotics and the effects of concurrent probiotics were evaluated in this study. This was a prospective study of 20 dogs undergoing hemilaminectomy...
March 2021: Canadian Veterinary Journal. la Revue Vétérinaire Canadienne
https://read.qxmd.com/read/33512803/probiotic-synbiotic-treatment-and-postoperative-complications-in-colorectal-cancer-patients-systematic-review-and-meta-analysis-of-randomized-controlled-trials
#35
JOURNAL ARTICLE
Efrat L Amitay, Prudence R Carr, Anton Gies, Dana Clarissa Laetsch, Hermann Brenner
Colorectal cancer (CRC) is a leading cause of morbidity and mortality. Post-CRC resection complications and lower quality of life (QoL) are associated with a lower long-term survival. Perioperative administration of probiotics/synbiotics might lower prevalence of side effects and improve QoL and survival among CRC patients. Medline, Web of Science, Cochrane database, Embase, and clinical trials registries were searched in January 2020. Altogether, 16 randomized placebo-controlled probiotic/synbiotic clinical trials that included patients undergoing CRC surgery and investigated postoperative complications and QoL side effects were found...
December 2020: Clinical and Translational Gastroenterology
https://read.qxmd.com/read/33506929/effects-of-lactobacillus-rhamnosus-gg-on-early-postoperative-outcome-after-pylorus-preserving-pancreatoduodenectomy-a-randomized-trial
#36
JOURNAL ARTICLE
M Folwarski, M Dobosz, S Małgorzewicz, K Skonieczna-Żydecka, K Kaźmierczak-Siedlecka
OBJECTIVE: Pancreatoduodenectomy (PPPD) remains one of the most complex surgical procedures with high complication rates. Infectious complications, postoperative ileus and delayed gastric emptying in the perioperative period have a significant impact on the recovery from the treatment. Probiotics (PB) are known to have a beneficial effect as supportive therapy in major abdominal surgery but the evidence in pancreatic surgery is still limited. The aim of the study was to assess the influence of postoperative administration of PB on the early outcomes after PPPD...
January 2021: European Review for Medical and Pharmacological Sciences
https://read.qxmd.com/read/33503110/effect-of-supplementation-with-probiotics-on-colonic-anastomoses-in-rats-morphological-and-tensiometric-study
#37
JOURNAL ARTICLE
Tiago Jacometo Coelho de Castilho, Gustavo Henrique Doná Rodrigues de Almeida, Eneri Vieira de S L Mello, Antônio Carlos L Campos
BACKGROUND: The use of probiotics positively modifies the composition and function of intestinal flora, improving the quality of intestinal anastomosis. AIM: To evaluate the impact of probiotic use on intestinal anastomosis of rats. METHOD: Thirty-six adult male Wistar rats (Rattus norvegicus albinus, Rodentia Mammalia) were used, with body weight ranging from 220-320 g. The animals were housed and acclimated individually in boxes receiving water and ration ad libitum...
2021: Brazilian Archives of Digestive Surgery: ABCD
https://read.qxmd.com/read/33204004/post-hoc-analysis-of-a-randomized-controlled-trial-on-the-impact-of-pre-transplant-use-of-probiotics-on-outcomes-after-liver-transplantation
#38
JOURNAL ARTICLE
M Grąt, K Grąt, M Krawczyk, Z Lewandowski, M Krasnodębski, Ł Masior, W Patkowski, K Zieniewicz
Perioperative use of probiotics serves as efficient prophylaxis against postoperative infections after liver transplantation, yet data on long-term effects of pre-transplant probiotic intake is lacking. The aim of this study was to assess the effects of pre-transplant probiotic administration on long-term results of liver transplantation. This was secondary analysis of a randomized trial. Patients were randomized to receive either 4-strain probiotic or placebo before liver transplantation. Five year graft survival was set as the primary end-point...
November 17, 2020: Scientific Reports
https://read.qxmd.com/read/32824268/effects-of-both-pro-and-synbiotics-in-liver-surgery-and-transplantation-with-special-focus-on-the-gut-liver-axis-a-systematic-review-and-meta-analysis
#39
JOURNAL ARTICLE
Judith Kahn, Gudrun Pregartner, Peter Schemmer
The gut-liver axis is of upmost importance for the development of infections after surgery. Further bacterial translocation due to surgery-related dysbiosis is associated with limited detoxification function of the liver compromising outcome of surgical therapy. After liver surgery, about 30% of patients develop a bacterial infection, with the risk of bacteremia or even sepsis-associated liver failure and mortality in >40%. The potential benefit of pro-/synbiotics given before surgery is still under debate...
August 15, 2020: Nutrients
https://read.qxmd.com/read/32667528/effects-of-probiotics-supplementation-on-skin-wound-healing-in-diabetic-rats
#40
JOURNAL ARTICLE
Letícia Fuganti Campos, Eliane Tagliari, Thais Andrade Costa Casagrande, Lúcia de Noronha, Antônio Carlos L Campos, Jorge Eduardo F Matias
BACKGROUND: Example of wound contraction area at: A) day of surgery in the control group; B) 7PO in the control group; C) day of surgery in the probiotic group; D) 7PO in probiotic group. Chronic wounds in patients with Diabetes Mellitus often become incurable due to prolonged and excessive production of inflammatory cytokines. The use of probiotics modifies the intestinal microbiota and modulates inflammatory reactions. AIM: To evaluate the influence of perioperative supplementation with probiotics in the cutaneous healing process in diabetic rats...
July 8, 2020: Brazilian Archives of Digestive Surgery: ABCD
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