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Perioperative antibiotics

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https://www.readbyqxmd.com/read/28816833/perioperative-use-of-erythromycin-reduces-cognitive-decline-after-coronary-artery-bypass-grafting-surgery-a-pilot-study
#1
Evanthia Thomaidou, Helena Argiriadou, Georgios Vretzakis, Kalliopi Megari, Nikolaos Taskos, Georgios Chatzigeorgiou, Kyriakos Anastasiadis
OBJECTIVES: Adverse neurologic outcome can be a debilitating complication after cardiac surgery. The aim of this study was to investigate the potential neuroprotective action of erythromycin, a well known antibiotic agent, regarding postoperative cognitive decline in patients undergoing cardiac surgery. METHODS: Forty patients scheduled for elective coronary artery bypass grafting surgery were prospectively randomly assigned in 2 groups: the erythromycin group (n = 19) who received erythromycin at a dose of 25 mg/kg before and after surgery and the control group (n = 21) who did not receive it...
August 14, 2017: Clinical Neuropharmacology
https://www.readbyqxmd.com/read/28814707/-transurethral-injection-using-deflux-for-vesicoureteral-reflux-in-three-adult-women-with-frequent-febrile-urinary-tract-infections
#2
Yoko Saito, Jun-Ichi Teranishi, Yohei Kumano, Masahiro Yasui, Syohei Mori, Shuko Yoneyama, Ayako Gobara, Takashi Kawahara, Hiroji Uemura
We report three patients with frequent febrile urinary tract infections (fUTI) who underwent transurethral injection therapy with Deflux for vesicoureteral reflux (VUR). The first case was in a 52-yearold woman who was initially diagnosed with right grade II and left grade I VUR at 18 years of age. She frequently experienced fUTI due to VUR. The second case was in a 29-year-old woman. At age 23,she was diagnosed with right grade III VUR when she developed fUTI. After that,she repeatedly developed fUTI. The third case was in a 40-year-old woman who had frequently experienced fUTI since 25 years of age and had gradually become antibiotics-resistant...
July 2017: Hinyokika Kiyo. Acta Urologica Japonica
https://www.readbyqxmd.com/read/28803455/effect-of-positive-perioperative-donor-and-recipient-respiratory-bacterial-cultures-on-early-post-transplant-outcomes-in-lung-transplant-recipients
#3
Crystal K Howell, Christopher A Paciullo, Marshall G Lyon, David Neujahr, Peter Lyu, George Cotsonis, Michael Hurtik
BACKGROUND: It is standard practice to administer prophylactic antibiotics post lung transplantation. However, no studies have evaluated the impact of culture positivity. The purpose of this study was to evaluate early post-transplant outcomes of culture-positive and culture-negative lung transplant (LT) recipients and the appropriateness of the empiric regimens used. METHODS: Adult patients who received an LT at Emory University Hospital between January 1, 2010 and August 31, 2015 were reviewed and stratified into three groups: (i) culture-positive appropriate empiric treatment, (ii) culture-positive inappropriate empiric treatment, and (iii) culture-negative...
August 13, 2017: Transplant Infectious Disease: An Official Journal of the Transplantation Society
https://www.readbyqxmd.com/read/28802796/antibacterial-prophylaxis-for-gram-positive-and-gram-negative-infections-in-cranial-surgery-a-meta-analysis
#4
REVIEW
Pranav Abraham, Nayan Lamba, Michael Acosta, Joanna Gholmie, Hassan Y Dawood, Matthew Vestal, Kevin Huang, Maher Hulou, Morteza Asgarzadeh, Hasan Zaidi, Rania A Mekary, Timothy R Smith
BACKGROUND: Perioperative antibiotic prophylaxis against gram positive and gram negative infections is considered standard of care in the perioperative management of patients undergoing cranial surgery. The antibiotic regimen which best reduces the risk of surgical site infections (SSIs) remains controversial. OBJECTIVES: A systematic literature review and meta-analysis were conducted to examine the effect of various prophylactic antibiotics on infection incidence among patients undergoing cranial surgeries...
August 9, 2017: Journal of Clinical Neuroscience: Official Journal of the Neurosurgical Society of Australasia
https://www.readbyqxmd.com/read/28800838/noncompliance-with-surgical-antimicrobial-prophylaxis-guidelines-a-jordanian-experience-in-cesarean-deliveries
#5
Mariam Hantash Abdel Jalil, Khawla Abu Hammour, Mervat Alsous, Rand Hadadden, Wedad Awad, Faris Bakri, Kamil Fram
BACKGROUND: Surgical site infections are common, especially in developing countries. Nevertheless, up to 60% of surgical site infections can be prevented with appropriate perioperative care, which includes among other measures using suitable surgical antimicrobial prophylaxis (SAP). METHODS: After a short interview with patients and retrospective review of medical charts, compliance with 6 SAP parameters was assessed for appropriateness; those parameters are indication, choice, dose, time of administration, intraoperative redosing interval, and duration of prophylaxis in 1,173 operations...
August 8, 2017: American Journal of Infection Control
https://www.readbyqxmd.com/read/28797044/what-can-we-learn-from-sonication-results-of-breast-implants
#6
Frederike M J Reischies, Robert Krause, Judith Holzer, Fabian Tiefenbacher, Raimund Winter, Gertraud Eylert, Tobias Meikl, Alexandru Tuca, Martin J Köfer, Lars P Kamolz, David B Lumenta
BACKGROUND: Different research groups have identified microorganisms on breast implants by sonication with significant correlation to the rate of capsular contracture. This substantiated the hypothesis of an infectious etiology of capsular contracture. However, no clinical consequence has been drawn from these results yet. Aim of this study was to review sonication results from breast implants and to evaluate the current preoperative antibiotic regime for breast-implant surgery. METHODS: We compared breast implant sonication culture results from published reports and our own database...
2017: PloS One
https://www.readbyqxmd.com/read/28781211/perioperative-antibiotic-use-in-diabetic-patients-a-retrospective-review-of-670-surgeries
#7
Justine S Ko, Samantha Zwiebel, Brigid Wilson, Devra B Becker
PURPOSE: Carpal tunnel syndrome (CTS) has a high incidence in diabetic patients, with a reported incidence up to 21%. In severe cases of CTS, patients may undergo carpal tunnel release (CTR) surgery, which involves the risk of infection and other complications. To decrease the risk of infection, some physicians provide prophylactic antibiotics. Our study examines the effects of prophylactic antibiotic use, especially in a high-risk, diabetic population. METHODS: A total of 469 CTR surgeries performed by plastic surgery specialists were reviewed for diabetic status at the time of surgery and perioperative antibiotic use...
July 8, 2017: Journal of Plastic, Reconstructive & Aesthetic Surgery: JPRAS
https://www.readbyqxmd.com/read/28780782/endophthalmitis-prophylaxis-for-cataract-surgery
#8
Aravind Haripriya, Zervin R Baam, David F Chang
Endophthalmitis after cataract surgery is a rare but potentially devastating complication. There is great variability in endophthalmitis prophylaxis practice patterns worldwide. Treatment varies globally and is based on the microbiological profile and availability of formulations. Periocular povidone-iodine antisepsis is universally adopted and considered the standard of care in most practices. Perioperative topical antibiotics are also very popular despite the lack of level 1 evidence confirming efficacy. Based on growing observational evidence, routine intracameral antibiotic prophylaxis is increasing, especially where approved commercial intraocular preparations are available...
July 2017: Asia-Pacific Journal of Ophthalmology
https://www.readbyqxmd.com/read/28767803/perioperative-care-in-bariatric-surgery-in-the-context-of-the-acerto-project-reality-versus-surgeons-assumptions-in-a-cuiab%C3%A3-hospital
#9
Jacqueline Jéssica De-Marchi, Mardem Machado De-Souza, Alberto Bicudo Salomão, José Eduardo de Aguilar Nascimento, Anyelle Almada Selleti, Erik de-Albuquerque, Katia Bezerra Veloso Mendes
Objective: to assess the level of knowledge among bariatric surgeons, about the recommendations of the ACERTO Project, correlating their assumptions on their perioperative prescriptions and the reality, according to the patients charts. Method: we conducted a prospective, longitudinal, observational study comparing the assumptions of bariatric surgeons obtained through responses on a specific questionnaire with the reality found in clinical data from the hospital records...
May 2017: Revista do Colégio Brasileiro de Cirurgiões
https://www.readbyqxmd.com/read/28721286/open-stone-surgery-a-still-in-use-approach-for-complex-stone-burden
#10
Özer Ural Çakici, Kemal Ener, Murat Keske, Serkan Altinova, Abdullah Erdem Canda, Mustafa Aldemir, Arslan Ardicoglu
INTRODUCTION: Urinary stone disease is a major urological condition. Endourologic techniques have influenced the clinical approach and outcomes. Open surgery holds a historic importance in the management of most conditions. However, complex kidney stone burden may be amenable to successful results with open stone surgery. In this article, we report our eighteen cases of complex urinary stone disease who underwent open stone removal. MATERIAL AND METHODS: A total of 1701 patients have undergone surgical treatment for urinary stone disease in our clinic between July 2012 and July 2016, comprising eighteen patients who underwent open stone surgery...
June 30, 2017: Central European Journal of Urology
https://www.readbyqxmd.com/read/28716178/short-term-morbidity-after-the-endoscopic-modified-lothrop-draf-iii-procedure-compared-with-draf-iia
#11
Aria Jafari, Kathryn R Tringale, Bharat A Panuganti, Joseph R Acevedo, John Pang, Adam S DeConde
BACKGROUND: The endoscopic modified Lothrop (Draf-III) surgery has improved treatment of recalcitrant frontal sinus disease, with favorable safety and long-term results. However, the short-term clinical and quality-of-life morbidity after Draf-III relative to less-extensive procedures has yet to be investigated. OBJECTIVE: To evaluate the surgical and quality-of-life outcomes, including the burden of follow-up care, in patients who underwent endoscopic modified Lothrop (Draf-III), and compared these results with a less-extensive intervention, the endoscopic frontal sinusotomy (Draf-IIa)...
July 1, 2017: American Journal of Rhinology & Allergy
https://www.readbyqxmd.com/read/28708024/quality-improvement-initiative-preventative-surgical-site-infection-protocol-in-vascular-surgery
#12
David Parizh, Enrico Ascher, Syed Ali Raza Rizvi, Anil Hingorani, Michael Amaturo, Eric Johnson
Objective A quality improvement initiative was employed to decrease single institution surgical site infection rate in open lower extremity revascularization procedures. SUMMARY BACKGROUND DATA: In an attempt to lower patient morbidity, we developed and implemented the Preventative Surgical Site Infection Protocol in Vascular Surgery. Surgical site infections lead to prolonged hospital stays, adjunctive procedure, and additive costs. We employed targeted interventions to address the common risk factors that predispose patients to post-operative complications...
January 1, 2017: Vascular
https://www.readbyqxmd.com/read/28700780/distinction-of-risk-factors-for-superficial-vs-organ-space-surgical-site-infections-after-pancreatic-surgery
#13
Irmina A Elliott, Carmen Chan, Tara A Russell, Amanda M Dann, Jennifer L Williams, Lauren Damato, Hallie Chung, Mark D Girgis, O Joe Hines, Howard A Reber, Timothy R Donahue
Importance: Surgical site infection (SSI) rates are increasingly used as a quality metric. However, risk factors for SSI in pancreatic surgery remain undefined. Objective: To stratify superficial and organ-space SSIs after pancreatectomy and investigate their modifiable risk factors. Design, Setting, and Participants: This retrospective analysis included 201 patients undergoing pancreatic surgery at a university-based tertiary referral center from July 1, 2013, through June 30, 2015, and 10 371 patients from National Surgical Quality Improvement Program-Hepatopancreaticobiliary (NSQIP-HPB) Collaborative sites from January 1, 2014, through December 31, 2015...
July 12, 2017: JAMA Surgery
https://www.readbyqxmd.com/read/28697103/chlorhexidine-alcohol-compared-with-povidone-iodine-for-preoperative-topical-antisepsis-for-abdominal-hysterectomy
#14
Shitanshu Uppal, Ali Bazzi, R Kevin Reynolds, John Harris, Mark D Pearlman, Darrell A Campbell, Daniel M Morgan
OBJECTIVE: To compare preoperative chlorhexidine-alcohol topical antiseptic agent with povidone-iodine in patients undergoing abdominal hysterectomy for benign indications. METHODS: A retrospective cohort study of patients undergoing abdominal hysterectomy from July 2012 to February 2015 in the Michigan Surgical Quality Collaborative was performed. The primary exposure was the use of chlorhexidine-alcohol or povidone-iodine. The primary outcome was surgical site infection within 30 days...
August 2017: Obstetrics and Gynecology
https://www.readbyqxmd.com/read/28692690/risk-of-surgical-site-infection-acute-kidney-injury-and-clostridium-difficile-infection-following-antibiotic-prophylaxis-with-vancomycin-plus-a-beta-lactam-versus-either-drug-alone-a-national-propensity-score-adjusted-retrospective-cohort-study
#15
MULTICENTER STUDY
Westyn Branch-Elliman, John E Ripollone, William J O'Brien, Kamal M F Itani, Marin L Schweizer, Eli Perencevich, Judith Strymish, Kalpana Gupta
BACKGROUND: The optimal regimen for perioperative antimicrobial prophylaxis is controversial. Use of combination prophylaxis with a beta-lactam plus vancomycin is increasing; however, the relative risks and benefits associated with this strategy are unknown. Thus, we sought to compare postoperative outcomes following administration of 2 antimicrobials versus a single agent for the prevention of surgical site infections (SSIs). Potential harms associated with combination regimens, including acute kidney injury (AKI) and Clostridium difficile infection (CDI), were also considered...
July 2017: PLoS Medicine
https://www.readbyqxmd.com/read/28687504/infected-abdominal-aortic-aneurysms-treated-with-extra-anatomic-prosthesis-bypass-in-the-retroperitoneum
#16
You-Fei Qi, Zhan-Xiang Xiao, Chang Shu, Jie Yue, Sa-Hua Liu, Hao Chen, Zhao-Fan Zeng, Wen-Bo Zhang
BACKGROUND: Infected abdominal aortic aneurysms (iAAAs) are rare but life-threatening diseases. The purpose of the present study was to report our experience of extra-anatomic prosthesis bypass in the retroperitoneum as a treatment for iAAAs. METHODS: Data of 8 consecutive patients diagnosed with iAAAs and treated by an extra-anatomic prosthesis bypass in the retroperitoneum were retrospectively collected. Operative details were as follows: one side of the retroperitoneal space was selected to build a track and a bifurcated ePTFE prosthesis was placed through the track...
July 4, 2017: Annals of Vascular Surgery
https://www.readbyqxmd.com/read/28684074/the-impact-of-surgical-intervention-and-antibiotics-on-mronj-stage-ii-and-iii-retrospective-study
#17
Matthias Zirk, Matthias Kreppel, Johannes Buller, Julij Pristup, Franziska Peters, Timo Dreiseidler, Max Zinser, Joachim E Zöller
OBJECTIVES: Metastatic bone disease and osteoporosis are the main indications for bisphosphonates and anti-resorptive agent therapy. Inhibition of bone turnover and angiogenesis are mainly responsible for the development of Medication Related Osteonecrosis of Jaws (MRONJ) as therapeutic side-effect. Yet, the role of infection for the development and recurrence of MRONJ is not fully elucidated. The aim of this retrospective study is to explore if a difference in antibiotic regimes has an impact on the surgical intervention needed to achieve a painless stable stage of the disease...
June 4, 2017: Journal of Cranio-maxillo-facial Surgery
https://www.readbyqxmd.com/read/28677576/methods-to-reduce-postoperative-surgical-site-infections-after-head-and-neck-oncology-surgery
#18
REVIEW
Richard B Cannon, Jeffrey J Houlton, Eduardo Mendez, Neal D Futran
Head and neck cancer surgery is often a complex multi-step procedure that includes major resections, vascularised tissue reconstruction, and extensive neck dissection. The upper aerodigestive tract mucosal lining is often disrupted during surgery, which requires the management of a clean-contaminated field and the need to reconstruct the mucosal lining. With bacterial contamination, surgical site infections (SSI) are a serious complication that can result in delayed wound healing, wound breakdown, fistula formation, and compromised tissue reconstruction...
July 2017: Lancet Oncology
https://www.readbyqxmd.com/read/28676409/enterococci-in-orthopaedic-infections-who-is-at-risk-getting-infected
#19
Ilker Uçkay, Daniela Pires, Americo Agostinho, Nastassia Guanziroli, Mehmet Öztürk, Placido Bartolone, Philippe Tscholl, Michael Betz, Didier Pittet
Some orthopaedic patients might be at risk for enterococcal infections and might benefit from adapted perioperative prophylaxis. METHODS: We performed a single-center cohort of adult patients with orthopaedic infections. RESULTS: Among 2740 infection episodes, 665 surgeries (24%) involved osteosynthesis material, including total joint arthroplasties. The recommended perioperative prophylaxis was cefuroxime (or vancomycin in case of documented MRSA body carriage)...
July 1, 2017: Journal of Infection
https://www.readbyqxmd.com/read/28660816/the-role-of-antimicrobial-sutures-in-preventing-surgical-site-infection
#20
D Leaper, P Wilson, O Assadian, C Edmiston, M Kiernan, A Miller, G Bond-Smith, J Yap
INTRODUCTION Healthcare associated infections (HCAIs) are falling following widespread and enforced introduction of guidelines, particularly those that have addressed antibiotic resistant pathogens such as methicillin resistant Staphylococcus aureus or emergent pathogens such as Clostridium difficile, but no such decline has been seen in the incidence of surgical site infection (SSI), either in the UK, the EU or the US. SSI is one of the HCAIs, which are all avoidable complications of a surgical patient's pathway through both nosocomial and community care...
July 2017: Annals of the Royal College of Surgeons of England
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