Fernanda Fortes de Araujo, Maha Abdeladhim, Clarissa Teixeira, Kelly Hummer, Matthew D Wilkerson, Roseanne Ressner, Ines Lakhal-Naouar, Michael W Ellis, Claudio Meneses, Saule Nurmukhambetova, Regis Gomes, W David Tolbert, George W Turiansky, Marzena Pazgier, Fabiano Oliveira, Jesus G Valenzuela, Shaden Kamhawi, Naomi Aronson
INTRODUCTION: Cutaneous leishmaniasis is a neglected vector-borne parasitic disease prevalent in 92 countries with approximately one million new infections annually. Interactions between vector saliva and the human host alter the response to infection and outcome of disease. METHODS: To characterize the human immunological responses developed against saliva of Phlebotomus duboscqi , a Leishmania major (L. major) vector, we repeatedly exposed the arms of 14 healthy U...
2024: Frontiers in Immunology