keyword
MENU ▼
Read by QxMD icon Read
search

neuropsychiatric aspects of

keyword
https://www.readbyqxmd.com/read/27932026/gene-environment-interactions-in-cortical-interneuron-development-and-dysfunction-a-review-of-preclinical-studies
#1
REVIEW
Lydia J Ansen-Wilson, Robert J Lipinski
Cortical interneurons (cINs) are a diverse group of locally projecting neurons essential to the organization and regulation of neural networks. Though they comprise only ∼20% of neurons in the neocortex, their dynamic modulation of cortical activity is requisite for normal cognition and underlies multiple aspects of learning and memory. While displaying significant morphological, molecular, and electrophysiological variability, cINs collectively function to maintain the excitatory-inhibitory balance in the cortex by dampening hyperexcitability and synchronizing activity of projection neurons, primarily through use of the inhibitory neurotransmitter gamma-aminobutyric acid (GABA)...
December 5, 2016: Neurotoxicology
https://www.readbyqxmd.com/read/27905952/mental-health-and-urban-living-in-sub-saharan-africa-major-depressive-episodes-among-the-urban-poor-in-ouagadougou-burkina-faso
#2
Géraldine Duthé, Clémentine Rossier, Doris Bonnet, Abdramane Bassiahi Soura, Jamaica Corker
BACKGROUND: In sub-Saharan African cities, the epidemiological transition has shifted a greater proportion of the burden of non-communicable diseases, including mental and behavioral disorder, to the adult population. The burden of major depressive disorder and its social risk factors in the urban sub-Saharan African population are not well understood and estimates vary widely. We conducted a study in Ouagadougou, Burkina Faso, in order to estimate the prevalence of major depressive episodes among adults in this urban setting...
May 5, 2016: Population Health Metrics
https://www.readbyqxmd.com/read/27889010/neuropsychiatric-aspects-of-concussion
#3
REVIEW
Rajiv Radhakrishnan, Amir Garakani, Lawrence S Gross, Marcia K Goin, Janet Pine, Andrew E Slaby, Calvin R Sumner, David A Baron
Over the past decade, concussion has become the most widely discussed injury in contact sports. However, concussions also occur in several other settings, such as non-contact sports, elderly individuals, young children, military personnel, and victims of domestic violence. Concussion is frequently undiagnosed as a cause of psychiatric morbidity, especially when the patient has no history of loss of consciousness or direct head trauma. Almost all of the extant literature focuses on traumatic brain injury and assumes that concussion is merely a mild form of traumatic brain injury, which has resulted in a lack of understanding about what concussion is, and how to diagnose, monitor, and treat its varied neuropsychiatric symptoms...
December 2016: Lancet Psychiatry
https://www.readbyqxmd.com/read/27877000/psychiatric-aspects-of-toxoplasmosis-an-indian-perspective
#4
Ajish G Mangot
Toxoplasma gondii is one of the well-studied parasites because of its medical and veterinary importance, and its suitability as a model for cell biology and molecular studies. Latent toxoplasmosis in an immunocompetent host was considered benign until recently. The importance of this parasite has been steadily rising in the field of psychiatry and neurology as it has been implicated in numerous neuropsychiatric disorders. Researchers in India have unfortunately restricted themselves to finding the prevalence of toxoplasma antibodies in special populations and animals...
December 2016: Journal of Parasitic Diseases: Official Organ of the Indian Society for Parasitology
https://www.readbyqxmd.com/read/27837170/differential-contributions-of-vasopressin-v1a-and-oxytocin-receptors-in-the-amygdala-to-pain-related-behaviors-in-rats
#5
Bryce Cragg, Guangchen Ji, Volker Neugebauer
Neuroplastic changes in the amygdala account for emotional-affective aspects of pain and involve neuropeptides such as calcitonin gene-related peptide and corticotropin-releasing factor. Another neuropeptide system, central arginine vasopressin, has been implicated in neuropsychiatric disorders, but its role in pain-related emotional expression and neuroplasticity remains to be determined. Here, we tested the hypothesis that arginine vasopressin in the amygdala contributes to pain-related emotional-affective responses, using stereotaxic applications of arginine vasopressin and antagonists for G-protein coupled vasopressin V1A and oxytocin receptors in adult male Sprague-Dawley rats...
2016: Molecular Pain
https://www.readbyqxmd.com/read/27833539/validity-of-quinpirole-sensitization-rat-model-of-ocd-linking-evidence-from-animal-and-clinical-studies
#6
REVIEW
Ales Stuchlik, Dominika Radostová, Hana Hatalova, Karel Vales, Tereza Nekovarova, Jana Koprivova, Jan Svoboda, Jiri Horacek
Obsessive-compulsive disorder (OCD) is a neuropsychiatric disorder with 1-3% prevalence. OCD is characterized by recurrent thoughts (obsessions) and repetitive behaviors (compulsions). The pathophysiology of OCD remains unclear, stressing the importance of pre-clinical studies. The aim of this article is to critically review a proposed animal model of OCD that is characterized by the induction of compulsive checking and behavioral sensitization to the D2/D3 dopamine agonist quinpirole. Changes in this model have been reported at the level of brain structures, neurotransmitter systems and other neurophysiological aspects...
2016: Frontiers in Behavioral Neuroscience
https://www.readbyqxmd.com/read/27787875/posterior-fossa-syndrome-review-of-the-behavioral-and-emotional-aspects-in-pediatric-cancer-patients
#7
REVIEW
Jane C Lanier, Annah N Abrams
Medulloblastoma, the most common malignant brain tumor of childhood, occurs in the posterior fossa, the part of the intracranial cavity that contains the brainstem and the cerebellum. The cerebellum is involved in many complex aspects of human behavior and function, and when it is disrupted or insulted, this can lead to significant sequelae in children with posterior fossa tumors. A constellation of impairing and distressing symptoms, including mutism, ataxia/hypotonia, and emotional lability, develops in approximately 25% of children after the surgical resection of posterior fossa tumors...
October 27, 2016: Cancer
https://www.readbyqxmd.com/read/27783238/putting-the-pieces-together-in-gilles-de-la-tourette-syndrome-exploring-the-link-between-clinical-observations-and-the-biological-basis-of-dysfunction
#8
REVIEW
Rowshanak Hashemiyoon, Jens Kuhn, Veerle Visser-Vandewalle
Gilles de la Tourette syndrome is a complex, idiopathic neuropsychiatric disorder whose pathophysiological mechanisms have yet to be elucidated. It is phenotypically heterogeneous and manifests more often than not with both motor and behavioral impairment, although tics are its clinical hallmark. Tics themselves present with a complex profile as they characteristically wax and wane and are often preceded by premonitory somatosensory sensations to which it is said a tic is the response. Highly comorbid with obsessive-compulsive disorder and attention deficit-hyperactivity disorder, it is purported to be an epigenetic, neurodevelopmental spectrum disorder with a complex genetic profile...
October 25, 2016: Brain Topography
https://www.readbyqxmd.com/read/27773782/obesity-current-and-potential-pharmacotherapeutics-and-targets
#9
REVIEW
Vidya Narayanaswami, Linda P Dwoskin
Obesity is a global epidemic that contributes to a number of health complications including cardiovascular disease, type 2 diabetes, cancer and neuropsychiatric disorders. Pharmacotherapeutic strategies to treat obesity are urgently needed. Research over the past two decades has increased substantially our knowledge of central and peripheral mechanisms underlying homeostatic energy balance. Homeostatic mechanisms involve multiple components including neuronal circuits, some originating in hypothalamus and brain stem, as well as peripherally-derived satiety, hunger and adiposity signals that modulate neural activity and regulate eating behavior...
October 20, 2016: Pharmacology & Therapeutics
https://www.readbyqxmd.com/read/27736679/prevalence-of-driving-under-the-influence-of-psychoactive-substances-and-road-traffic-crashes-among-brazilian-crack-using-drivers
#10
Juliana Nichterwitz Scherer, Roberta Silvestrin, Felipe Ornell, Vinícius Roglio, Tanara Rosangela Vieira Sousa
BACKGROUND: Substance use disorders are associated with the increased risk of driving under the influence (DUI), but little is known about crack-cocaine and its relationship with road traffic crashes (RTC). METHOD: A multicenter sample of 765 crack-cocaine users was recruited in six Brazilian capitals in order to estimate the prevalence of DUI and RTC involvement. Legal, psychiatric, and drug-use aspects related with traffic safety were evaluated using the Addiction Severity Index - 6th version (ASI-6) and the Mini International Neuropsychiatric Interview...
October 1, 2016: Drug and Alcohol Dependence
https://www.readbyqxmd.com/read/27719860/psychologic-functional-forms-of-memory-disorder
#11
J Griem, J Stone, A Carson, M D Kopelman
In this chapter, we discuss the wide variety of patients who may attend a memory clinic or other health services presenting with memory symptoms but who do not have dementia. These diagnoses may include a wide range of neurologic and neuropsychiatric disorders; in this chapter we will focus on other causes of memory symptoms which may be labeled psychologic or functional, or be more obviously part of an established psychiatric disorder. We describe the differential categorization recently posited by Stone et al...
2017: Handbook of Clinical Neurology
https://www.readbyqxmd.com/read/27718271/neuropsychiatric-aspects-of-22q11-2-deletion-syndrome-considerations-in-the-prenatal-setting
#12
Anne S Bassett, Gregory Costain, Christian R Marshall
Most major neuropsychiatric outcomes of concern to families are not detectable by prenatal ultrasound. The introduction of genome-wide chromosomal microarray analysis to prenatal clinical diagnostic testing has increased the detection of pathogenic 22q11.2 deletions, which cause the most common genomic disorder. The recent addition of this and other microdeletions to non-invasive prenatal screening methods using cell-free fetal DNA has further propelled interest in outcomes. Conditions associated with 22q11...
October 8, 2016: Prenatal Diagnosis
https://www.readbyqxmd.com/read/27714914/a-pilot-study-of-potential-brain-donor-satisfaction-and-attitudes-towards-telephone-assessment
#13
Helen Costello, Gillian M Hayes, Elizabeth Highton-Williamson, Shirley Nurock, Dave Hanbury, Paul T Francis
OBJECTIVE: Test the feasibility of assessing cognition, psychiatric symptoms and daily living skills of potential brain donors by telephone and compare satisfaction and attitudes across telephone and face-to-face assessment. METHOD: Data were collected from 108 healthy participants from the Brains for Dementia Research cohort. Purposive sampling was used to assess feasibility and a randomised control trial design compared satisfaction and attitudes towards telephone and face-to-face assessment...
October 7, 2016: International Journal of Geriatric Psychiatry
https://www.readbyqxmd.com/read/27682995/prader-willi-syndrome-mental-health-research-strategy-workshop-proceedings-the-state-of-the-science-and-future-directions
#14
Lauren Schwartz, Anthony Holland, Elisabeth Dykens, Theresa Strong, Elizabeth Roof, Jessica Bohonowych
: This paper reports on the 'Prader-Willi Syndrome (PWS) Mental Health Research Strategy Workshop' that took place in March 2015. PWS is characterized by a complex phenotype affecting multiple systems with a high prevalence of maladaptive behaviours, and neuropsychiatric illness. Prader Willi syndrome results from the absence of paternally derived alleles located at the imprinted chromosomal locus, 15q11-13. The goal of the workshop was to highlight the state of the science of the mental health of people with this rare neurodevelopmental disorder...
September 29, 2016: Orphanet Journal of Rare Diseases
https://www.readbyqxmd.com/read/27676211/determinants-of-quality-of-life-in-young-onset-dementia-results-from-a-european-multicenter-assessment
#15
Joany Millenaar, Lara Hvidsten, Marjolein E de Vugt, Knut Engedal, Geir Selbæk, Torgeir Bruun Wyller, Aud Johannessen, Per Kristian Haugen, Christian Bakker, Deliane van Vliet, Raymond T C M Koopmans, Frans R J Verhey, Hege Kersten
BACKGROUND: Promoting adaptation, improving well-being and maintaining an optimal quality of life (QOL) is an important aspect in dementia care. The purpose of this study was to identify determinants of QOL in young onset dementia, and to assess differences in QoL domains between people with Alzheimer's disease (AD) and frontotemporal dementia (FTD). METHODS: In total 135 persons with AD and 58 persons with FTD were included from two prospective cohort studies. QOL was assessed with the proxy reported quality of life in Alzheimer's disease questionnaire (QoL-AD)...
September 27, 2016: Aging & Mental Health
https://www.readbyqxmd.com/read/27606315/altered-brain-structure-function-relationships-underlie-executive-dysfunction-in-22q11-2-deletion-syndrome
#16
Rachel K Jonas, Maria Jalbrzikowski, Caroline A Montojo, Arati Patel, Leila Kushan, Carolyn C Chow, Therese Vesagas, Carrie E Bearden
22q11.2 deletion syndrome (22q11DS) is a neurogenetic disorder associated with elevated rates of developmental neuropsychiatric disorders and impaired executive function (EF). Disrupted brain structure-function relationships may underlie EF deficits in 22q11DS. We administered the Behavior Rating Inventory of Executive Function (BRIEF) to assess real-world EF in patients with 22q11DS and matched controls (n = 86; age 6-17 years), along with cognitive measures that tap behavioral regulation and metacognition aspects of EF...
December 2015: Molecular Neuropsychiatry
https://www.readbyqxmd.com/read/27602003/executive-dysfunctions-the-role-in-attention-deficit-hyperactivity-and-post-traumatic-stress-neuropsychiatric-disorders
#17
REVIEW
Lía Martínez, Edward Prada, Corina Satler, Maria C H Tavares, Carlos Tomaz
Executive functions (EFs) is an umbrella term for various cognitive processes controlled by a complex neural activity, which allow the production of different types of behaviors seeking to achieve specific objectives, one of them being inhibitory control. There is a wide consensus that clinical and behavioral alterations associated with EF, such as inhibitory control, are present in various neuropsychiatric disorders. This paper reviews the research literature on the relationship between executive dysfunction, frontal-subcortical neural circuit changes, and the psychopathological processes associated with attention deficit hyperactivity disorder (ADHD) and post-traumatic stress disorder (PTSD)...
2016: Frontiers in Psychology
https://www.readbyqxmd.com/read/27574128/alterations-in-anxiety-and-social-behaviour-in-npas4-deficient-mice-following-photochemically-induced-focal-cortical-stroke
#18
T S Klarić, E J Jaehne, S A Koblar, B T Baune, M D Lewis
In addition to causing widespread cell death and loss of brain function, cerebral ischaemia also induces extensive neuroplasticity. In humans, stroke is often accompanied by severe cognitive and psychiatric changes that are thought to arise as a consequence of this infarct-induced remodelling. A candidate for producing these post-stroke neuropsychiatric changes is Npas4, an activity-dependent transcription factor involved in synaptic plasticity whose expression is aberrantly up-regulated following ischaemic injury...
January 1, 2017: Behavioural Brain Research
https://www.readbyqxmd.com/read/27546201/cognitive-and-social-functioning-deficits-after-anti-n-methyl-d-aspartate-receptor-encephalitis-an-exploratory-case-series
#19
Gemma L McKeon, James G Scott, Donna M Spooner, Alexander E Ryan, Stefan Blum, David Gillis, Daman Langguth, Gail A Robinson
BACKGROUND: Anti-N-methyl-D-aspartate receptor (NMDAR) encephalitis is a recently described life-threatening autoimmune disorder associated with a characteristic multi-stage neuropsychiatric syndrome. Although it is known that the majority of patients experience neuropsychological disturbance post-treatment, some aspects of the cognitive profile remain unclear. METHODS: This study sought to investigate patterns of cognitive functioning in a sample of anti-NMDAR encephalitis patients...
September 2016: Journal of the International Neuropsychological Society: JINS
https://www.readbyqxmd.com/read/27531975/on-the-effect-of-sex-on-prefrontal-and-cerebellar-neurometabolites-in-healthy-adults-an-mrs-study
#20
Dominique Endres, Ludger Tebartz van Elst, Bernd Feige, Stephan Backenecker, Kathrin Nickel, Anna Bubl, Thomas Lange, Irina Mader, Simon Maier, Evgeniy Perlov
In neuropsychiatric research, the aspects of sex have received increasing attention over the past decade. With regard to the neurometabolic differences in the prefrontal cortex and the cerebellum of both men and women, we performed a magnetic resonance spectroscopic (MRS) study of a large group of healthy subjects. For neurometabolic measurements, we used single-voxel proton MRS. The voxels of interest (VOI) were placed in the pregenual anterior cingulate cortex (pACC) and the left cerebellar hemisphere. Absolute quantification of creatine (Cre), total choline (t-Cho), glutamate and glutamine (Glx), N-acetylaspartate, and myo-inositol (mI) was performed...
2016: Frontiers in Human Neuroscience
keyword
keyword
86012
1
2
Fetch more papers »
Fetching more papers... Fetching...
Read by QxMD. Sign in or create an account to discover new knowledge that matter to you.
Remove bar
Read by QxMD icon Read
×

Search Tips

Use Boolean operators: AND/OR

diabetic AND foot
diabetes OR diabetic

Exclude a word using the 'minus' sign

Virchow -triad

Use Parentheses

water AND (cup OR glass)

Add an asterisk (*) at end of a word to include word stems

Neuro* will search for Neurology, Neuroscientist, Neurological, and so on

Use quotes to search for an exact phrase

"primary prevention of cancer"
(heart or cardiac or cardio*) AND arrest -"American Heart Association"