Kevin P Kennedy, Jeanne L Alexander, Amir Garakani, Lawrence S Gross, David L Mintz, Tapan Parikh, Janet H Pine, Calvin R Sumner, David A Baron
PURPOSE OF REVIEW: Vitamin B12 (B12, cobalamin) deficiency has been associated with neuropsychiatric symptoms, suggesting a role for B12 supplementation both as a treatment for psychiatric symptoms due to B12 deficiency and as an augmentation strategy for pharmacological treatments of psychiatric disorders. This critical review discusses the major causes of B12 deficiency, the range of psychiatric and non-psychiatric manifestations of B12 deficiency, the indications for testing B12 levels, and the evidence for B12 supplementation for major psychiatric disorders...
May 2, 2024: Current Psychiatry Reports