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https://www.readbyqxmd.com/read/28346442/identification-of-12-new-susceptibility-loci-for-different-histotypes-of-epithelial-ovarian-cancer
#1
Catherine M Phelan, Karoline B Kuchenbaecker, Jonathan P Tyrer, Siddhartha P Kar, Kate Lawrenson, Stacey J Winham, Joe Dennis, Ailith Pirie, Marjorie J Riggan, Ganna Chornokur, Madalene A Earp, Paulo C Lyra, Janet M Lee, Simon Coetzee, Jonathan Beesley, Lesley McGuffog, Penny Soucy, Ed Dicks, Andrew Lee, Daniel Barrowdale, Julie Lecarpentier, Goska Leslie, Cora M Aalfs, Katja K H Aben, Marcia Adams, Julian Adlard, Irene L Andrulis, Hoda Anton-Culver, Natalia Antonenkova, Gerasimos Aravantinos, Norbert Arnold, Banu K Arun, Brita Arver, Jacopo Azzollini, Judith Balmaña, Susana N Banerjee, Laure Barjhoux, Rosa B Barkardottir, Yukie Bean, Matthias W Beckmann, Alicia Beeghly-Fadiel, Javier Benitez, Marina Bermisheva, Marcus Q Bernardini, Michael J Birrer, Line Bjorge, Amanda Black, Kenneth Blankstein, Marinus J Blok, Clara Bodelon, Natalia Bogdanova, Anders Bojesen, Bernardo Bonanni, Åke Borg, Angela R Bradbury, James D Brenton, Carole Brewer, Louise Brinton, Per Broberg, Angela Brooks-Wilson, Fiona Bruinsma, Joan Brunet, Bruno Buecher, Ralf Butzow, Saundra S Buys, Trinidad Caldes, Maria A Caligo, Ian Campbell, Rikki Cannioto, Michael E Carney, Terence Cescon, Salina B Chan, Jenny Chang-Claude, Stephen Chanock, Xiao Qing Chen, Yoke-Eng Chiew, Jocelyne Chiquette, Wendy K Chung, Kathleen B M Claes, Thomas Conner, Linda S Cook, Jackie Cook, Daniel W Cramer, Julie M Cunningham, Aimee A D'Aloisio, Mary B Daly, Francesca Damiola, Sakaeva Dina Damirovna, Agnieszka Dansonka-Mieszkowska, Fanny Dao, Rosemarie Davidson, Anna DeFazio, Capucine Delnatte, Kimberly F Doheny, Orland Diez, Yuan Chun Ding, Jennifer Anne Doherty, Susan M Domchek, Cecilia M Dorfling, Thilo Dörk, Laure Dossus, Mercedes Duran, Matthias Dürst, Bernd Dworniczak, Diana Eccles, Todd Edwards, Ros Eeles, Ursula Eilber, Bent Ejlertsen, Arif B Ekici, Steve Ellis, Mingajeva Elvira, Kevin H Eng, Christoph Engel, D Gareth Evans, Peter A Fasching, Sarah Ferguson, Sandra Fert Ferrer, James M Flanagan, Zachary C Fogarty, Renée T Fortner, Florentia Fostira, William D Foulkes, George Fountzilas, Brooke L Fridley, Tara M Friebel, Eitan Friedman, Debra Frost, Patricia A Ganz, Judy Garber, María J García, Vanesa Garcia-Barberan, Andrea Gehrig, Aleksandra Gentry-Maharaj, Anne-Marie Gerdes, Graham G Giles, Rosalind Glasspool, Gord Glendon, Andrew K Godwin, David E Goldgar, Teodora Goranova, Martin Gore, Mark H Greene, Jacek Gronwald, Stephen Gruber, Eric Hahnen, Christopher A Haiman, Niclas Håkansson, Ute Hamann, Thomas V O Hansen, Patricia A Harrington, Holly R Harris, Jan Hauke, Alexander Hein, Alex Henderson, Michelle A T Hildebrandt, Peter Hillemanns, Shirley Hodgson, Claus K Høgdall, Estrid Høgdall, Frans B L Hogervorst, Helene Holland, Maartje J Hooning, Karen Hosking, Ruea-Yea Huang, Peter J Hulick, Jillian Hung, David J Hunter, David G Huntsman, Tomasz Huzarski, Evgeny N Imyanitov, Claudine Isaacs, Edwin S Iversen, Louise Izatt, Angel Izquierdo, Anna Jakubowska, Paul James, Ramunas Janavicius, Mats Jernetz, Allan Jensen, Uffe Birk Jensen, Esther M John, Sharon Johnatty, Michael E Jones, Päivi Kannisto, Beth Y Karlan, Anthony Karnezis, Karin Kast, Catherine J Kennedy, Elza Khusnutdinova, Lambertus A Kiemeney, Johanna I Kiiski, Sung-Won Kim, Susanne K Kjaer, Martin Köbel, Reidun K Kopperud, Torben A Kruse, Jolanta Kupryjanczyk, Ava Kwong, Yael Laitman, Diether Lambrechts, Nerea Larrañaga, Melissa C Larson, Conxi Lazaro, Nhu D Le, Loic Le Marchand, Jong Won Lee, Shashikant B Lele, Arto Leminen, Dominique Leroux, Jenny Lester, Fabienne Lesueur, Douglas A Levine, Dong Liang, Clemens Liebrich, Jenna Lilyquist, Loren Lipworth, Jolanta Lissowska, Karen H Lu, Jan Lubinński, Craig Luccarini, Lene Lundvall, Phuong L Mai, Gustavo Mendoza-Fandiño, Siranoush Manoukian, Leon F A G Massuger, Taymaa May, Sylvie Mazoyer, Jessica N McAlpine, Valerie McGuire, John R McLaughlin, Iain McNeish, Hanne Meijers-Heijboer, Alfons Meindl, Usha Menon, Arjen R Mensenkamp, Melissa A Merritt, Roger L Milne, Gillian Mitchell, Francesmary Modugno, Joanna Moes-Sosnowska, Melissa Moffitt, Marco Montagna, Kirsten B Moysich, Anna Marie Mulligan, Jacob Musinsky, Katherine L Nathanson, Lotte Nedergaard, Roberta B Ness, Susan L Neuhausen, Heli Nevanlinna, Dieter Niederacher, Robert L Nussbaum, Kunle Odunsi, Edith Olah, Olufunmilayo I Olopade, Håkan Olsson, Curtis Olswold, David M O'Malley, Kai-Ren Ong, N Charlotte Onland-Moret, Nicholas Orr, Sandra Orsulic, Ana Osorio, Domenico Palli, Laura Papi, Tjoung-Won Park-Simon, James Paul, Celeste L Pearce, Inge Søkilde Pedersen, Petra H M Peeters, Bernard Peissel, Ana Peixoto, Tanja Pejovic, Liisa M Pelttari, Jennifer B Permuth, Paolo Peterlongo, Lidia Pezzani, Georg Pfeiler, Kelly-Anne Phillips, Marion Piedmonte, Malcolm C Pike, Anna M Piskorz, Samantha R Poblete, Timea Pocza, Elizabeth M Poole, Bruce Poppe, Mary E Porteous, Fabienne Prieur, Darya Prokofyeva, Elizabeth Pugh, Miquel Angel Pujana, Pascal Pujol, Paolo Radice, Johanna Rantala, Christine Rappaport-Fuerhauser, Gad Rennert, Kerstin Rhiem, Patricia Rice, Andrea Richardson, Mark Robson, Gustavo C Rodriguez, Cristina Rodríguez-Antona, Jane Romm, Matti A Rookus, Mary Anne Rossing, Joseph H Rothstein, Anja Rudolph, Ingo B Runnebaum, Helga B Salvesen, Dale P Sandler, Minouk J Schoemaker, Leigha Senter, V Wendy Setiawan, Gianluca Severi, Priyanka Sharma, Tameka Shelford, Nadeem Siddiqui, Lucy E Side, Weiva Sieh, Christian F Singer, Hagay Sobol, Honglin Song, Melissa C Southey, Amanda B Spurdle, Zsofia Stadler, Doris Steinemann, Dominique Stoppa-Lyonnet, Lara E Sucheston-Campbell, Grzegorz Sukiennicki, Rebecca Sutphen, Christian Sutter, Anthony J Swerdlow, Csilla I Szabo, Lukasz Szafron, Yen Y Tan, Jack A Taylor, Muy-Kheng Tea, Manuel R Teixeira, Soo-Hwang Teo, Kathryn L Terry, Pamela J Thompson, Liv Cecilie Vestrheim Thomsen, Darcy L Thull, Laima Tihomirova, Anna V Tinker, Marc Tischkowitz, Silvia Tognazzo, Amanda Ewart Toland, Alicia Tone, Britton Trabert, Ruth C Travis, Antonia Trichopoulou, Nadine Tung, Shelley S Tworoger, Anne M van Altena, David Van Den Berg, Annemarie H van der Hout, Rob B van der Luijt, Mattias Van Heetvelde, Els Van Nieuwenhuysen, Elizabeth J van Rensburg, Adriaan Vanderstichele, Raymonda Varon-Mateeva, Ana Vega, Digna Velez Edwards, Ignace Vergote, Robert A Vierkant, Joseph Vijai, Athanassios Vratimos, Lisa Walker, Christine Walsh, Dorothea Wand, Shan Wang-Gohrke, Barbara Wappenschmidt, Penelope M Webb, Clarice R Weinberg, Jeffrey N Weitzel, Nicolas Wentzensen, Alice S Whittemore, Juul T Wijnen, Lynne R Wilkens, Alicja Wolk, Michelle Woo, Xifeng Wu, Anna H Wu, Hannah Yang, Drakoulis Yannoukakos, Argyrios Ziogas, Kristin K Zorn, Steven A Narod, Douglas F Easton, Christopher I Amos, Joellen M Schildkraut, Susan J Ramus, Laura Ottini, Marc T Goodman, Sue K Park, Linda E Kelemen, Harvey A Risch, Mads Thomassen, Kenneth Offit, Jacques Simard, Rita Katharina Schmutzler, Dennis Hazelett, Alvaro N Monteiro, Fergus J Couch, Andrew Berchuck, Georgia Chenevix-Trench, Ellen L Goode, Thomas A Sellers, Simon A Gayther, Antonis C Antoniou, Paul D P Pharoah
To identify common alleles associated with different histotypes of epithelial ovarian cancer (EOC), we pooled data from multiple genome-wide genotyping projects totaling 25,509 EOC cases and 40,941 controls. We identified nine new susceptibility loci for different EOC histotypes: six for serous EOC histotypes (3q28, 4q32.3, 8q21.11, 10q24.33, 18q11.2 and 22q12.1), two for mucinous EOC (3q22.3 and 9q31.1) and one for endometrioid EOC (5q12.3). We then performed meta-analysis on the results for high-grade serous ovarian cancer with the results from analysis of 31,448 BRCA1 and BRCA2 mutation carriers, including 3,887 mutation carriers with EOC...
March 27, 2017: Nature Genetics
https://www.readbyqxmd.com/read/28342925/epidemiology-and-characteristics-of-neurosurgical-conditions-at-mbarara-regional-referral-hospital
#2
Jihad Abdelgadir, Emily R Smith, Maria Punchak, Joao Ricardo Vissoci, Catherine Staton, Alex Muhindo, David Kitya, Lawrence P Park, Michael M Haglund
BACKGROUND: The unmet surgical need, specifically neurosurgical need, in Uganda is significant, yet only two public hospitals currently perform neurosurgery in the country. This study examines the epidemiology and outcomes of neurosurgical conditions presenting to one of 12 regional referral hospitals in Uganda, in an effort to understand the neurosurgical needs of this population. METHODS: The study was conducted at Mbarara Regional Referral Hospital (MRRH), in southwestern Uganda...
March 23, 2017: World Neurosurgery
https://www.readbyqxmd.com/read/28336445/mortality-associated-characteristics-of-traumatic-brain-injury-patients-at-the-university-teaching-hospital-of-kigali-rwanda
#3
Elizabeth Krebs, Charles J Gerardo, Lawrence P Park, Joao Ricardo Nickenig Vissoci, Jean Claude Byiringiro, Fidele Byiringiro, Stephen Rulisa, Nathan Thielman, Catherine Staton
OBJECTIVE: Traumatic Brain Injury (TBI) is a leading cause of death and disability. TBI patients in low and middle- income countries have worse outcomes than those in high-income countries. We aimed to evaluate important clinical indicators associated with mortality for TBI patients at the University Teaching Hospital of Kigali (UTHK) Kigali, Rwanda. METHODS: Prospective consecutive sampling of TBI patients presenting to UTHK Accident and Emergency Department were screened for inclusion criteria: reported head trauma, alteration in consciousness, headache, or visible head trauma...
March 21, 2017: World Neurosurgery
https://www.readbyqxmd.com/read/28332713/the-mitochondrial-pentatricopeptide-repeat-protein-ppr19-is-involved-in-the-stabilization-of-nadh-dehydrogenase-1-transcripts-and-is-crucial-for-mitochondrial-function-and-arabidopsis-thaliana-development
#4
Kwanuk Lee, Ji Hoon Han, Youn-Il Park, Catherine Colas des Francs-Small, Ian Small, Hunseung Kang
Despite the importance of pentatricopeptide repeat (PPR) proteins in organellar RNA metabolism and plant development, the functions of many PPR proteins remain unknown. Here, we determined the role of a mitochondrial PPR protein (At1g52620) comprising 19 PPR motifs, thus named PPR19, in Arabidopsis thaliana. The ppr19 mutant displayed abnormal seed development, reduced seed yield, delayed seed germination, and retarded growth, indicating that PPR19 is indispensable for normal growth and development of Arabidopsis thaliana...
March 23, 2017: New Phytologist
https://www.readbyqxmd.com/read/28322663/factors-affecting-korean-neonatal-infant-pain-care
#5
Haeyoung Min, Catherine Vincent, Alicia K Matthews, Linda L McCreary, Chang G Park, Margot Latimer
This study aimed to translate three English-language instruments-Pain Knowledge and Use (PKU), Collaboration and Satisfaction About Care Decisions (CSACD), and Environmental Complexity Scale (ECS)-into Korean and evaluate the equivalence of the instrument versions. Three Korean translators and two senior reviewers translated the instruments' 56 items using a committee approach. Eight Korean experts evaluated the cultural relevance of the translated instruments using a content validity index (CVI), and 12 Korean neonatal nurses were interviewed to assess their understanding of items...
January 1, 2017: Western Journal of Nursing Research
https://www.readbyqxmd.com/read/28320379/mirnas-associated-with-prostate-cancer-risk-and-progression
#6
REVIEW
Hung N Luu, Hui-Yi Lin, Karina Dalsgaard Sørensen, Olorunseun O Ogunwobi, Nagi Kumar, Ganna Chornokur, Catherine Phelan, Dominique Jones, LaCreis Kidd, Jyotsna Batra, Kosj Yamoah, Anders Berglund, Robert J Rounbehler, Mihi Yang, Sang Haak Lee, Nahyeon Kang, Seung Joon Kim, Jong Y Park, Giuliano Di Pietro
Prostate cancer is the most common malignancy among men in the US. Though considerable improvement in the diagnosis of prostate cancer has been achieved in the past decade, predicting disease outcome remains a major clinical challenge. Recent expression profiling studies in prostate cancer suggest microRNAs (miRNAs) may serve as potential biomarkers for prostate cancer risk and disease progression. miRNAs comprise a large family of about 22-nucleotide-long non-protein coding RNAs, regulate gene expression post-transcriptionally and participate in the regulation of numerous cellular processes...
March 20, 2017: BMC Urology
https://www.readbyqxmd.com/read/28314818/allometric-analysis-detects-brain-size-independent-effects-of-sex-and-sex-chromosome-complement-on-human-cerebellar-organization
#7
Catherine Mankiw, Min Tae M Park, P K Reardon, Ari M Fish, Liv S Clasen, Deanna Greenstein, Jay N Giedd, Jonathan D Blumenthal, Jason P Lerch, M Mallar Chakravarty, Armin Raznahan
The cerebellum is a large hindbrain structure that is increasingly recognized for its contribution to diverse domains of cognitive and affective processing in human health and disease. Although several of these domains are sex-biased, our fundamental understanding of cerebellar sex differences - including their spatial distribution, potential biological determinants, and independence from brain volume variation - lags far behind that for the cerebrum. Here, we harness automated neuroimaging methods for cerebellar morphometrics in 417 individuals to (i) localize normative male-female differences in raw cerebellar volume, (ii) compare these to sex chromosome effects estimated across five rare X-/Y-chromosome aneuploidy (SCA) syndromes, and (iii) clarify brain size-independent effects of sex and SCA on cerebellar anatomy using a generalizable allometric approach which considers scaling relationships between regional cerebellar volume and brain volume in health...
March 17, 2017: Journal of Neuroscience: the Official Journal of the Society for Neuroscience
https://www.readbyqxmd.com/read/28263311/a-subset-of-platinum-containing-chemotherapeutic-agents-kills-cells-by-inducing-ribosome-biogenesis-stress
#8
Peter M Bruno, Yunpeng Liu, Ga Young Park, Junko Murai, Catherine E Koch, Timothy J Eisen, Justin R Pritchard, Yves Pommier, Stephen J Lippard, Michael T Hemann
Cisplatin and its platinum analogs, carboplatin and oxaliplatin, are some of the most widely used cancer chemotherapeutics. Although cisplatin and carboplatin are used primarily in germ cell, breast and lung malignancies, oxaliplatin is instead used almost exclusively to treat colorectal and other gastrointestinal cancers. Here we utilize a unique, multi-platform genetic approach to study the mechanism of action of these clinically established platinum anti-cancer agents, as well as more recently developed cisplatin analogs...
February 27, 2017: Nature Medicine
https://www.readbyqxmd.com/read/28223512/glucosylceramide-synthase-inhibition-alleviates-aberrations-in-synucleinopathy-models
#9
S Pablo Sardi, Catherine Viel, Jennifer Clarke, Christopher M Treleaven, Amy M Richards, Hyejung Park, Maureen A Olszewski, James C Dodge, John Marshall, Elina Makino, Bing Wang, Richard L Sidman, Seng H Cheng, Lamya S Shihabuddin
Mutations in the glucocerebrosidase gene (GBA) confer a heightened risk of developing Parkinson's disease (PD) and other synucleinopathies, resulting in a lower age of onset and exacerbating disease progression. However, the precise mechanisms by which mutations in GBA increase PD risk and accelerate its progression remain unclear. Here, we investigated the merits of glucosylceramide synthase (GCS) inhibition as a potential treatment for synucleinopathies. Two murine models of synucleinopathy (a Gaucher-related synucleinopathy model, Gba(D409V/D409V) and a A53T-α-synuclein overexpressing model harboring wild-type alleles of GBA, A53T-SNCA mouse model) were exposed to a brain-penetrant GCS inhibitor, GZ667161...
March 7, 2017: Proceedings of the National Academy of Sciences of the United States of America
https://www.readbyqxmd.com/read/28142286/neighborhood-social-cohesion-as-a-mediator-of-neighborhood-conditions-on-mothers-engagement-in-physical-activity
#10
Paula J Yuma-Guerrero, Catherine Cubbin, Kirk von Sternberg
OBJECTIVES: The purpose of this study was to determine if social cohesion mediates the effects of neighborhood and household-level socioeconomic status (SES), perceptions of neighborhood safety, and access to parks on mothers' engagement in physical activity (PA). METHOD: Secondary analyses were conducted on cross-sectional data from The Geographic Research on Wellbeing (GROW) study. GROW includes survey data from a diverse sample of 2,750 California mothers. Structural equation modeling was used to test a conceptual multilevel mediation model, proposing social cohesion as a mediator of known predictors of PA...
January 1, 2017: Health Education & Behavior: the Official Publication of the Society for Public Health Education
https://www.readbyqxmd.com/read/28130426/genetic-analysis-of-ten-pedigrees-with-inherited-retinal-degeneration-ird-by-exome-sequencing-and-phenotype-genotype-association
#11
Pooja Biswas, Jacque L Duncan, Bruno Maranhao, Igor Kozak, Kari Branham, Luis Gabriel, Jonathan H Lin, Guilio Barteselli, Mili Navani, John J Suk, Michelle Parke, Catherine Schlechter, Richard Weleber, John R Heckenlively, Gislin Dagnelie, Pauline Lee, S Amer Riazuddin, Radha Ayyagari
PURPOSE: To identify causative mutations and characterize the phenotype associated with the genotype in ten unrelated families with autosomal recessive retinal degeneration. METHODS: Ophthalmic evaluation and DNA isolation was carried out in 10 pedigrees with IRD. Exomes of probands from 8 pedigrees were captured using Nimblegen V2/V3 or Agilent V5+UTR kits, and sequencing was performed on Illumina HiSeq. The DHDDS gene was screened for mutations in the remaining two pedigrees with Ashkenazi Jews ancestry...
January 27, 2017: Physiological Genomics
https://www.readbyqxmd.com/read/28128342/primary-human-placental-trophoblasts-are-permissive-for-zika-virus-zikv-replication
#12
Kjersti M Aagaard, Anismrita Lahon, Melissa A Suter, Ravi P Arya, Maxim D Seferovic, Megan B Vogt, Min Hu, Fabio Stossi, Michael A Mancini, R Alan Harris, Maike Kahr, Catherine Eppes, Martha Rac, Michael A Belfort, Chun Shik Park, Daniel Lacorazza, Rebecca Rico-Hesse
Zika virus (ZIKV) is an emerging mosquito-borne (Aedes genus) arbovirus of the Flaviviridae family. Although ZIKV has been predominately associated with a mild or asymptomatic dengue-like disease, its appearance in the Americas has been accompanied by a multi-fold increase in reported incidence of fetal microcephaly and brain malformations. The source and mode of vertical transmission from mother to fetus is presumptively transplacental, although a causal link explaining the interval delay between maternal symptoms and observed fetal malformations following infection has been missing...
January 27, 2017: Scientific Reports
https://www.readbyqxmd.com/read/28119487/stag1-mutations-cause-a-novel-cohesinopathy-characterised-by-unspecific-syndromic-intellectual-disability
#13
Daphné Lehalle, Anne-Laure Mosca-Boidron, Amber Begtrup, Odile Boute-Benejean, Perrine Charles, Megan T Cho, Amanda Clarkson, Orrin Devinsky, Yannis Duffourd, Laurence Duplomb-Jego, Bénédicte Gérard, Aurélia Jacquette, Paul Kuentz, Alice Masurel-Paulet, Carey McDougall, Sébastien Moutton, Hilde Olivié, Soo-Mi Park, Anita Rauch, Nicole Revencu, Jean-Baptiste Rivière, Karol Rubin, Ingrid Simonic, Deborah J Shears, Thomas Smol, Ana Lisa Taylor Tavares, Paulien Terhal, Julien Thevenon, Koen Van Gassen, Catherine Vincent-Delorme, Marjolein H Willemsen, Golder N Wilson, Elaine Zackai, Christiane Zweier, Patrick Callier, Christel Thauvin-Robinet, Laurence Faivre
BACKGROUND: Cohesinopathies are rare neurodevelopmental disorders arising from a dysfunction in the cohesin pathway, which enables chromosome segregation and regulates gene transcription. So far, eight genes from this pathway have been reported in human disease. STAG1 belongs to the STAG subunit of the core cohesin complex, along with five other subunits. This work aimed to identify the phenotype ascribed to STAG1 mutations. METHODS: Among patients referred for intellectual disability (ID) in genetics departments worldwide, array-comparative genomic hybridisation (CGH), gene panel, whole-exome sequencing or whole-genome sequencing were performed following the local diagnostic standards...
January 24, 2017: Journal of Medical Genetics
https://www.readbyqxmd.com/read/28074415/proceedings-of-r%C3%A3-animation-2017-the-french-intensive-care-society-international-congress
#14
Wulfran Bougouin, Eloi Marijon, Benjamin Planquette, Nicole Karam, Florence Dumas, David Celermajer, Daniel Jost, Lionel Lamhaut, Frankie Beganton, Alain Cariou, Guy Meyer, Xavier Jouven, Côme Bureau, Julien Charpentier, Omar Ben Hadj Salem, Lucie Guillemet, Michel Arnaout, Alexis Ferre, Guillaume Geri, Nicolas Mongardon, Frédéric Pène, Jean-Daniel Chiche, Jean-Paul Mira, Guylaine Labro, François Belon, Vinh-Phuc Luu, Julien Chenet, Guillaume Besch, Marc Puyraveau, Gaël Piton, Gilles Capellier, Maëlle Martin, Jean-Baptiste Lascarrou, Aurélie Le Thuaut, Jean-Claude Lacherade, Laurent Martin-Lefèvre, Maud Fiancette, Isabelle Vinatier, Christine Lebert, Konstantinos Bachoumas, Aihem Yehia, Matthieu Henry-Laguarrigue, Gwenhaël Colin, Jean Reignier, Elodie Privat, Joséphine Escutnaire, Cyrielle Dumont, Valentine Baert, Christian Vilhelm, Hervé Hubert, Vincent Robert-Edan, Karim Lakhal, Andrew Quartin, Brian Hobbs, Cynthia Cely, Cynthia Bell, Tai Pham, Roland Schein, Yimin Geng, Chaan Ng, Stephan Ehrmann, Charlotte Salmon Gandonnière, Julie Boisramé-Helms, Olivier Le Tilly, Isabelle Benz De Bretagne, Emmanuelle Mercier, Julie Mankikian, Anne Bretagnol, Ferhat Meziani, Jean Michel Halimi, Chantal Barin Le Guellec, Stéphane Gaudry, David Hajage, Florence Tubach, Bertrand Pons, Eric Boulet, Alexandre Boyer, Guillaume Chevrel, Nicolas Lerolle, Dorothée Carpentier, Nicolas de Prost, Alexandre Lautrette, Julien Mayaux, Saad Nseir, Jean-Damien Ricard, Didier Dreyfuss, René Robert, Franscesco Garzotto, Eric Kipnis, Ciro Tetta, Claudio Ronco, David Schnell, Bourmaud Aurelie, Marie Reynaud, Christophe Clec'h, Mourad Benyamina, François Vincent, Christophe Mariat, Caroline Bornstain, Stephane Rouleau, Christophe Leroy, Yves Cohen, Jerome Morel, Matthieu Legrand, Jeremy Terreaux, Michaël Darmon, Marie Cantier, Adeline Morisot, Emmanuel Guérot, Emmanuel Canet, Etienne De Montmollin, Guillaume Voiriot, Mathilde Neuville, Jean-François Timsit, Romain Sonneville, Abdallah Fayssoil, Tania Stojkovic, Anthony Behin, Adam Ogna, Frédéric Lofaso, Pascal Laforet, Karim Wahbi, Helene Prigent, Denis Duboc, David Orlikowski, Bruno Eymard, Djillali Annane, Loic Le Guennec, Clémentine Cholet, Nicolas Bréchot, Guillaume Hekimian, Sébastien Besset, Guillaume Lebreton, Ania Nieszkowska, Jean Louis Trouillet, Pascal Leprince, Alain Combes, Charles-Edouard Luyt, Marion Griton, Musa Sesay, Nadia Sibaï De Panthou, Thomas Bienvenu, Matthieu Biais, Karine Nouette-Gaulain, Guillaume Fossat, Florian Baudin, Cécile Coulanges, Sabrine Bobet, Arnaud Dupont, Léa Courtes, Dalila Benzekri, Toufik Kamel, Grégoire Muller, Nicolas Bercault, François Barbier, Isabelle Runge, Marie Skarzynski, Armelle Mathonnet, Thierry Boulain, Youenn Jouan, Noémie Teixera, Claire Hassen-Khodja, Antoine Guillon, Christophe Gaborit, Leslie Grammatico-Guillon, Cécile Rebière, Elie Azoulay, Benoit Misset, Stephane Ruckly, Maïté Garrouste-Orgeas, Nancy Kentish-Barnes, Jacques Duranteau, Marie Thuong, Liliane Joseph, Anne Renault, Olivier Lesieur, Anne-Gaelle Si Larbi, Gérald Viquesnel, Benjamin Zuber, Sophie Marque, Stanislas Kandelman, Nicolas Pichon, Bernard Floccard, Marion Galon, Sylvie Chevret, Nancy Kentish-Barnes, Valérie Seegers, Stéphane Legriel, Samir Jaber, Jean Yves Lefrant, Danielle Reuter, Olivier Guisset, Christophe Cracco, Amélie Seguin, Jacques Durand-Gasselin, Marine Thirion, Zoé Cohen-Solal, Hélène Foulgoc, Julien Rogier, Elsa Delobbe, Frédérique Schortgen, Pierre Asfar, Boisramé-Helms Julie, David Grimaldi, Grelon Fabien, Nadia Anguel, Lasocki Sigismond, Henry-Lagarrigue Matthieu, Frédéric Gonzalez, Legay François, Christophe Guitton, Maleka Schenck, Doise Jean-Marc, Peter Radermacher, Nancy Kentish-Barnes, Joseph Nsiala Makunza, Mejeni Kamdem Nathalie, Akilimali Pierre, Kilembe Manzanza Adolphe, Rafael Mahieu, Thomas Reydel, Angéline Jamet, Nicolas Chudeau, Julien Huntzinger, Steven Grange, Anne Courte, Jérémie Lemarie, Sébastien Gibot, Julia Champey, Jean Dellamonica, Damien Du Cheyron, Damien Contou, Jean-Marc Tadié, Martin Cour, Gaetan Beduneau, Antoine Marchalot, Laurent Guérin, Sebastien Jochmans, Nicolas Terzi, Sebastien Preau, Christian Brun-Buisson, Armand Mekontso Dessap, Meryl Vedrenne-Cloquet, Sophie Breinig, Camille Jung, Maxime Brussieux, Marie-Odile Marcoux, Xavier Durrmeyer, Renaud Blondé, François Angoulvant, Jérôme Grasset, Jérôme Naudin, Stéphane Dauger, Solenn Remy, Karine Kolev-Descamp, Julie Demaret, Guillaume Monneret, Etienne Javouhey, Maryline Chomton, Michaël Sauthier, Emilie Vallieres, Philippe Jouvet, Guillaume Geslain, Isabelle Guellec, Jérôme Rambaud, Matthieu Schmidt, Peter Schellongowski, Amandine Dorget, Nicolo Patroniti, Fabio Silvio Taccone, Dinis Reis Miranda, Jean Reuter, Hélène Prodanovic, Marc Pierrot, Martin Balik, Sunghoon Park, Claude Guérin, Laurent Papazian, Reignier Jean, Louis Ayzac, Anderson Loundou, Jean-Marie Forel, Mehdi Mezidi, Mylène Aublanc, Sophie Perinel-Ragey, Floriane Lissonde, Aurore Louf-Durier, Romain Tapponnier, Hodane Yonis, Remi Coudroy, Jean-Pierre Frat, Florence Boissier, Arnaud W Thille, Flore Richard, Hélène Le Gullou-Guillemette, Jonathan Fahri, Achille Kouatchet, Laetitia Bodet-Contentin, Denis Garot, Déborah Le Pennec, Laurent Vecellio, Elsa Tavernier, Pierre François Dequin, Jonathan Messika, Yolaine Martin, Natacha Maquigneau, Christelle Puechberty, Annabelle Stoclin, Serge Villard, Aline Dechanet, Audrey De Jong, Marion Monnin, Mehdi Girard, Gérald Chanques, Nicolas Molinari, Maxens Decavèle, Sébastien Campion, Roukia Ainsouya, Marie-Cécile Niérat, Mathieu Raux, Thomas Similowski, Alexandre Demoule, Keyvan Razazi, Martial Tchir, Faten May, Guillaume Carteaux, Rougevin-Baville Pauline, Andronikof Marc, Jean Pierre Bedos, Koukabi Mehrsa, Carole Mauger-Briche, François Mijon, Pierre Trouiller, Benjamin Sztrymf, Pierre Cretallaz, Romain Mermillod-Blondin, Dominique Savary, Ines Sedghiani, Hamdi Doghri, Asma Jendoubi, Dhekra Hamdi, Mohamed Ali Cherif, Youssef Zied El Hechmi, Jerbi Zouheir, Nicolas Persico, Francois Maltese, Cécile Ferrigno, Amandine Bablon, Cécile Marmillot, Antoine Roch, Ines Sedghiani, Grégory Papin, Marc Gainnier, Laurent Argaud, Adrie Christophe, Bertrand Souweine, Dany Goldgran-Toledano, Guillaume Marcotte, Anne Sylvie Dumenil, Schwebel Carole, Jerôme Cecchini, Samuel Tuffet, Muriel Fartoukh, Damien Roux, Martial Thyrault, Mekontso Dessap Armand, Simon Chauveau, Nadège Wesner, Laurence Monnier-Cholley, Naïke Bigé, Hafid Ait-Oufella, Bertrand Guidet, Vincent Dubée, Pierre Labroca, Jérémie Lemarié, Gérard Chiesa, Isabelle Laroyenne, Léo Borrini, Rémi Klotz, Quoc Phan Sy, Marie-Christine Cristina, Jean Paysant, Pierre Fillâtre, Arnaud Gacouin, Matthieu Revest, Pierre Tattevin, Erwan Flecher, Yves Le Tulzo, Matthieu Jamme, Fabrice Daviaud, Nathalie Marin, Michael Thy, Baptiste Duceau, Fanny Ardisson, Valade Sandrine, Marion Venot, Benoît Schlemmer, Lara Zafrani, Stéphanie Pons, Lenka Styfalova, Lila Bouadma, Aguila Radjou, Jordane Lebut, Bruno Mourvillier, Richard Dorent, Marie-Pierre Dilly, Patrick Nataf, Michel Wolff, Aëlle Le Gall, Simon Bourcier, Yacine Tandjaoui-Lambiotte, Vincent Das, Mikael Alves, Naïke Bigé, Chtara Kamilia, Ammar Rania, Najeh Baccouch, Olfa Turki, Hmida Chokri Ben, Mabrouk Bahloul, Mounir Bouaziz, Claire Dupuis, Anne Perozziello, Julien Letheulle, Marc Valette, Cécile Herrmann-Storck, Laura Crosby, Khalid Elkoun, Benjamin Madeux, Frédéric Martino, Hélène Migueres, Pascale Piednoir, Matthias Posch, Guillaume Thiery, Minh-Tu Huynh-Ky, Pierre Alexandre Bouchard, Jean-François Sarrazin, François Lellouche, Mai-Anh Nay, Brice Lortat-Jacob, Bertrand Rozec, Marion Colnot, Nicolas Belin, Loïc Barrot, Jean-Christophe Navellou, Cyrille Patry, Claire Chaignat, Melanie Claveau, Frédéric Claude, Cécile Aubron, Zoe Mcquilten, Michael Bailey, Jasmin Board, Heidi Buhr, Bruce Cartwright, Mark Dennis, Paul Forrest, Carol Hodgson, David Mcilroy, Deirdre Murphy, Lynnette Murray, Vincent Pellegrino, David Pilcher, Jayne Sheldrake, Huyen Tran, Shirley Vallance, Jamie Cooper, Camille Bombled, Charles Vidal, Dimitri Margetis, Julien Amour, Domien Coart, Jasperina Dubois, Tom Van Herpe, Dieter Mesotten, Sébastien Bailly, Jc Lucet, Alain Lepape, François L'hériteau, Martine Aupée, Caroline Bervas, Sandrine Boussat, Anne Berger-Carbonne, Anaïs Machut, Anne Savey, Jean-Jacques Tudesq, Sandrine Valade, Lionel Galicier, Cédric De Bazelaire, Nicolas Munoz-Bongrand, Xavier Mignard, Lucie Biard, Djamel Mokart, Martine Nyunga, Fabrice Bruneel, Antoine Rabbat, Pierre Perez, Anne Pascale Meert, Dominique Benoit, Eric Mariotte, Franck Ehooman, Rebecca Hamidfar-Roy, Yannick Hourmant, Arnaud Mailloux, Alexandra Beurton, Jean-Louis Teboul, Valentina Girroto, Galarza Laura, Christian Richard, Xavier Monnet, Vincent Dubée, Hamid Merdji, Julien Dang, Gabriel Preda, Jean-Luc Baudel, Cyrielle Desnos, Michel Zeitouni, Ines Belaroussi, Antoine Parrot, Clarisse Blayau, Jean-Pierre Fulgencio, Christophe Quesnel, Vincent Labbe, Marc Pineton De Chambrun, François Beloncle, Sybille Merceron, Yannick Fedun, Bernard Lecomte, Jérôme Devaquet, Marc Puidupin, Bruno Verdière, Zahir Amoura, Constance Vuillard, Jais Xavier, Delphine Bourlier, Amar David, Sattler Caroline, Montani David, Simmoneau Gerald, Sitbon Olivier, Marc Humbert, Savale Laurent, Olivier Dujardin, Adrien Bouglé, Hamou Nora Ait, Joe Elie Salem, Najoua El-Helali, Zoé Coppere, Aude Gibelin, Clementine Taconet, Michel Djibre, Adel Maamar, Elen Colobert, Pierre Fillatre, Fabrice Uhel, Christophe Camus, Josquin Moraly, Redouane Dahoumane, Eric Maury, Boun Kim Tan, Vivier Emmanuel, Misslin Pauline, Parmeland Laurence, Poirié Philippe, Jean-Ralph Zahar, Haond Catherine, Pommier Christian, Ait-Bouziad Karim, Hocine Mounia, Témime Laura, Vero Hanitra Rasoldier, Guy Mager, Jean-Pierre Eraldi, Stéphanie Gelinotte, François Bougerol, Julien Dehay, Jean-Philippe Rigaud, Pierre Louis Declercq, Julien Michel, Nejla Aissa, Sandrine Henard, Philippe Guerci, Ichraq Latar, Bruno Levy, Nicolas Girerd, Antoine Kimmoun, Saousen Ben Abdallah, Sabrine Nakaa, Kmar Hraiech, Dhouha Ben Braiek, Ali Adhieb, Abdelwaheb M'ghirbi, Ali Ousji, Zeineb Hammouda, Fekri Abroug, Walid Sellami, Zied Hajjej, Walid Samoud, Iheb Labbene, Mustapha Ferjani, Fatma Kaaniche Medhioub, Rania Allela, Najla Ben Algia, Samar Cherif, Delphine Attia, Andrianjafy Herinjatovo, Xavier Laborne Francois, Med Aziz Bouhouri, Mohamed Taoufik Slaoui, A Soufi, K Khaleq, D Hamoudi, A Nsiri, R Harrar, Eric Maury, Suzanne Goursaud, Maxime Gauberti, Paul-Emile Labeyrie, Thomas Gaberel, Véronique Agin, Eric Maubert, Denis Vivien, Clément Gakuba, Anwar Armel, Rchi Abdou, Samira Kalouch, Khalid Yaqini, Aziz Chlilek, Walid Sellami, Soumaya Ben Yedder, Alexandre Tonnelier, Fabien Hervé, Guillaume Halley, Jean-Luc Frances, Mickael Moriconi, Mathieu Saoli, Aude Garnero, Didier Demory, Jean Michel Arnal, Bertrand Canoville, Cédric Daubin, Jennifer Brunet, Hassen Ben Ghezala, Salah Snouda, Chiekh Imen Ben, Moez Kaddour, Islem Ouanes, Mahdi Marzouk, Françoise Haniez, Hélène Jaillet, Henri Maas, Pierre Andrivet, Christian Darné, François Viau, Hassen Ben Ghezala, Islem Ouanes, Laurence Dangers, Claire Montlahuc, Sébastien Perbet, Islem Ouanes, Zeineb Hamouda, Sabrine Nakee, Lamia Ouanes-Besbes, Khaoula Meddeb, Ahmed Khedher, Nesrine Sma, Jihene Ayachi, Messaouda Khelfa, Nesrine Fraj, Hend Ben Lakhal, Hedia Hammed, Raja Boukadida, Hajer Hafsa, Imed Chouchene, Mohamed Boussarsar, Braiek Dhouha Ben, Lamia Ouanes-Besbes, Kaoutar Benatti, A Dafir, W Aissaoui, W Elallame, W Haddad, R Cherkab, C Elkettani, L Barrou, Zakaria Ait Hamou, Xavier Repessé, Cyril Charron, Alix Aubry, Alexis Paternot, Julien Maizel, Michel Slama, Antoine Vieillard-Baron, Ahlem Trifi, Sami Abdellatif, Meriem Fatnassi, Foued Daly, Rochdi Nasri, Khaoula Ben Ismail, Salah Ben Lakhal, Florian Bazalgette, Aurelien Daurat, Claire Roger, Laurent Muller, Denis Doyen, Rémi Plattier, Alexandre Robert, Hervé Hyvernat, Gilles Bernardin, Mathieu Jozwiak, Julia Gimenez, Pablo Mercado, François Depret, Najla Tilouch, Houda Mater, Ben Sik Ali Habiba, Oussama Jaoued, Rim Gharbi, Mohamed Fekih Hassen, Souheil Elatrous, Pierre Pasquier, Quentin Vuillemin, Jean-Vivien Schaal, Thibault Martinez, Sandrine Duron, Marion Trousselard, Pierre-Eric Schwartzbrod, Thomas Baugnon, Laurent Dupic, Caroline Duracher Gout, Laure De Saint Blanquat, Sylvie Séguret, Gaelle Le Ficher, Gilles Orliaguet, Philippe Hubert, Naïke Bigé, Guillaume Leblanc, Raphael Briand, Lucas Brousse, Valentine Brunet, Léonard Chatelain, Dominique Prat, Frédéric Jacobs, Nadège Demars, Olfa Hamzaoui, Guy Moneger, Benjamin Sztrymf, Emilie Duburcq-Gury, Léa Satre-Buisson, Thibault Duburcq, Julien Poissy, Laurent Robriquet, Merce Jourdain, Thierry Sécheresse, Mattéo Miquet, Alexis Simond, Pascal Usseglio, Yamina Hamdaoui, Mohamed Boussarsar, Victoire Desailly, Patrick Brun, Pauline Iglesias, Jérémie Huet, Clémence Masseran, Antoine Claudon, Clément Ebeyer, Thomas Truong, Antoine Tesnière, Alexandre Mignon, Stéphane Gaudry, Dabor Resiere, Ruddy Valentino, Julien Fabre, Benoit Roze, Jean-Louis Ferge, Cyrille Charbatier, Sabia Marie, Michel Scholsser, Signate Aitsatou, Mathieu Raad, Andre Cabie, Hossein Mehdaoui, Clement Cousin, Christophe Rousseau, Jean-François Llitjos, Fanny Alby-Laurent, Julie Toubiana, Nadia Belaidouni, Marlène Cherruault, Jérome Tamburini, Didier Bouscary, Sarah Fert, Eugénie Delile, Emmanuel Besnier, David Coquerel, Rémi Nevière, Vincent Richard, Fabienne Tamion, Chaojie Wei, Huguette Louis, Schmitt Margaux, Albuisson Eliane, Orlowski Sophie, Antoine Kimmoun, Zakaria Riad, Marine Coroir, Bernard Rémy, Bombled Camille, Jeremie Joffre, Philippe Aegerter, Dejan Ilic, Marc Ginet, Caroline Pignard, Philippe Nguyen, Guillaume Mourey, Emmanuel Samain, Sebastien Pili-Floury, Romain Jouffroy, Caill Nicolas, Jean-Claude Alvarez, Maraffi Tomasso, Pascal Philippe, Jean-Herlé Raphalen, J Baud Frédéric, Benoit Vivien, Carli Pierre, Frederic Baud, Hana Fredj, Youssef Blel, Nozha Brahmi, Hassen Ben Ghezala, Anne-Sophie Hanak, Isabelle Malissin, Joel Poupon, Patricia Risede, Lucie Chevillard, Bruno Megarbane, Manel Barghouth, Aymen M'rad, Marwa Ben Hmida, Hafedh Thabet, Hao Liang, Jacques Callebert, Camille Lagard, Bruno Megarbane, Sahar Habacha, Bassem Chatbri, Christophe Camillerapp, Laurence Labat, Marion Soichot, Pierre Garçon, Antoine Goury, Lamia Kerdjana, Sebastian Voicu, Nicolas Deye, Bruno Megarbane, Anwar Armel, Benqqa Anas, Mezgui Othman, S Moumine, S Kalouch, K K Yakini, A Chlilek, Ahmed Hajji, Assaad Louati, Ammar Khaldi, Aida Borgi, Nargess Ghali, Asma Bouziri, Khaled Menif, Jaballah Najla Ben, Anwar Armel, Jeanne Brochon, Mihaela Dumitrescu, Sarah Thévenot, Jean-Pascal Saulnier, Khaled Husseini, Catherine Laland, Julie Cremniter, Anne Bousseau, Olivier Castel, Cassandra Brémaud-Csizmadia, Margot Diss, Aurélie Portefaix, Julien Berthiller, Yves Gillet, Nabil Tabet Aoul, Ali Douah, Zakaria Addou, Houari Youbi, Mohamed Moussati, Kamel Belhabiche, Souad Mir, Sanaa Abada, Zerhouni Amel, Nabil Aouffen, Zina Bouzit, Ahmed H Grati, Gilles F Dhonneur, Mohamed Boussarsar, Nicolas Lau, Ilham Mezhari, Nicolas Roucaud, Matthieu Le Meur, Rémi Paulet, Jean-Michel Coudray, Wahiba Imène Ghomari, Reda Boumlik, Vincent Peigne, Jean-Louis Daban, Mathieu Boutonnet, Bernard Lenoir, Hafiani Yassine, Cheikh Chaigar Mohamed, Allali Khalid, Moussaid Ihssan, Elyoussoufi Said, Salmi Said, Amira Ben Jazia, Jaziri Fatima, Skouri Wafa, Bennasr Maha, Ben Abdelghni Khaoula, Turki Sami, B Abdallah Taeib, Fatma Kaaniche Medhioub, Virginie Rollet-Cohen, Philippe Sachs, Zied Merchaoui, Sylvain Renolleau, Mehdi Oualha, Maxime Eloi, Sandrine Jean, Maryne Demoulin, Cécile Valentin, Julia Guilbert, Hervé Walti, Ricardo Carbajal, Pierre-Louis Leger, Yasemin Karaca-Altintas, Astrid Botte, Julien Labreuche, Elodie Drumez, Patrick Devos, Franck Bour, Francis Leclerc, Ayari Ahmed, Menif Khaled, Assaad Louati, Borgi Aida, Khaldi Ammar, Ghali Narjess, Hajji Ahmed, Bouziri Asma, Nejla Ben Jaballah, Pierre-Louis Leger, Julien Pansiot, Valérie Besson, Bruno Palmier, Olivier Baud, Bruno Cauli, Christiane Charriaut-Marlangue, Amélie Mansuy, Fabrice Michel, Stéphane Le Bel, Julia Boubnova, Fabrice Ughetto, Caroline Ovaert, Virginie Fouilloux, Olivier Paut, Matthias Jacquet-Lagrèze, Nicolas Tiebergien, Najib Hanna, Jean-Noël Evain, Florent Baudin, Sonia Courtil-Teyssedre, Dominique Bompard, Marc Lilot, Laurent Chardonal, Jean-Luc Fellahi, Claire Claverie, Guillaume Pouessel, Aimée Dorkenoo, Jean-Marie Renaudin, Mireille Eb, Antoine Deschildre, Stéphane Leteurtre, Hafiani Yassine, Belkadi Kamal, Oboukhlik Adil, Aalalam Ouafa, Moussaoui Mouhamed, Charkab Rachid, Barrou Lahoucine, Fahmi Dachraoui, Sabrine Nakkaa, Hammouda Zaineb, Dorra Mlika, Olfa Gloulou, Mohamed Boussarsar, Setti-Aouicha Zelmat, Djamila-Djahida Batouche, Belkacem Chaffi, Fatima Mazour, Nadia Benatta, Ines Fathallah, Rafaa Aloui, Aymen Zoubli, Nadia Kouraichi, Ines Fathallah, N Kouraichi, Shireen Salem, Eric Vicaut, Bruno Megarbane, David Ambroise, Anne-Marie Loriot, Emmanuel Bourgogne, Bruno Megarbane, Hatem Ghadhoune, Guissouma Jihene, Insaf Trabelsi, Hend Allouche, Habib Brahmi, Mohamed Samet, Hatem El Ghord, Rodolphe Lebeau, Jean-Louis Laplanche, Nadia Benturquia, Bruno Megarbane, Youssef Blel, A M'rad, Fatma Essafi, A Benabderrahim, Romain Jouffroy, Dabor Resiere, Bruno Sanchez, Jocelyn Inamo, Bruno Megarbane, Djamila-Djahida Batouche, Amel Zerhouni, Kheira Tabeliouna, Amine Negadi, Zahia Mentouri, Fanny Le Gall, Jean-Luc Hanouz, Hervé Normand, Abdo Khoury, Fatimata Seydou Sall, Alban De Luca, Aurore Pugin, Lionel Pazart, Chrystelle Vidal, Franck Leroux, Abdo Khoury, Erwan L'Her, Nicolas Marjanovic, Abdo Khoury, Thibault Desmettre, Christophe Lambert, Sophie Perinel Ragey, Loredana Baboi, Jean-Etienne Bazin, Catherine Koffel, Gilles Dhonneur, Zina Bouzit, Larbi Bradai, Issam Ben Ayed, Fethi Aissa, Hakim Haouache, Yoann Marechal, Patrick Biston, Michael Piagnerelli, Perrine Bortolotti, Delphine Colling, Vincent Colas, Benoit Voisin, Florent Dewavrin, Thierry Onimus, Patrick Girardie, Fabienne Saulnier, Tomas Urbina, Yann Nguyen, Anne-Lise Druoton, Marc Soudant, Damien Barraud, Marie Conrad, Aurélie Cravoisy-Popovic, Lionel Nace, Pierre-Edouard Bollaert, Ruste Martin, Laurent Bitker, Jean-Christophe Richard, David Brossier, Isabelle Goyer, Christopher Marquis, Marie Lampin, Alain Duhamel, Hélène Béhal, Tahar Dhaoui, Véronique Godeffroy, Eve Devouge, Dominique Evrard, Florence Delepoulle, Sylvie Racoussot, Bruno Grandbastien, Marie Lampin, Claire Heilbronner, Emeline Roy, Alexandra Masson, Alice Hadchouel-Duvergé, Virginie Rigourd, Elise Delacroix, Isabelle Wroblewski, Isabelle Pin, Anne Ego, Valerie Payen, Thierry Debillon, Anne Millet, Julien Denot, Véronique Berthelot, Emilie Thueux, Marie Reymond, Alexandra De Larrard, Alain Amblard, Pierre-Louis Leger, Nabil Tabet Aoul, Virginie Lemiale, Johanna Oziel, Noelle Brule, Anne-Sophie Moreau, Takoua Marhbène, Salma Sellami, Amira Jamoussi, Samia Ayed, Emna Mhiri, Leila Slim, Jalila Ben Khelil, Mohamed Besbes, Sylvain Chawki, Aicha Hamdi, Magali Ciroldi, Alice Cottereau, Edouard Obadia, Yoann Zerbib, Claire Andrejak, Sylvie Ricome, Hervé Dupont, François Baudin, Pauline Dureau, Audrey Tanguy, Charlotte Arbelot, Hassen Kais Ben, Ahmed Charfeddine, Benjamin Granger, Lucile Laporte, Coralie Hermetet, Kais Regaieg, Rim Khemakhem, Hedi Chelly, Chaigar Mohammed Cheikh, Hamid Mountij, Kawtar Rghioui, Wafae Haddad, Rachid Cherkab, Houcine Barrou, Aitmouden Naima, Othmani M Bennani, Kais Regaieg, Ahmed Douib, Amal Samet, Pierre-Julien Cungi, Cédric Nguyen, Jean Cotte, Erwan D'aranda, Eric Meaudre, Jean-Phillipe Avaro, Mohamed Taoufik Slaoui, Amel Mokline, Imene Rahmani, Achraf Laajili, Helmi Amri, Lazheri Gharsallah, Bahija Gasri, Sofiene Tlaili, Rym Hammouda, Amen Allah Messadi
No abstract text is available yet for this article.
January 2017: Annals of Intensive Care
https://www.readbyqxmd.com/read/28069024/efficient-method-for-establishing-f1-progeny-from-wild-populations-of-anopheles-mosquitoes
#15
Thiery N Nepomichene, Lala Andrianaivolambo, Sébastien Boyer, Catherine Bourgouin
BACKGROUND: The changing malaria situation in Madagascar requires additional knowledge on the physiology and behaviour of local mosquito vectors. However, the absence of established colonies for several anopheline species present in Madagascar constitutes a limiting factor. To avoid labour intensive work and uncertainty for success of establishing Anopheles colonies from Malagasy species, field collections of blood-fed females and in-tube forced oviposition were combined to reliably produce large numbers of F1 progeny...
January 9, 2017: Malaria Journal
https://www.readbyqxmd.com/read/28052456/frontoparietal-activation-during-visual-conjunction-search-effects-of-bottom-up-guidance-and-adult-age
#16
David J Madden, Emily L Parks, Catherine W Tallman, Maria A Boylan, David A Hoagey, Sally B Cocjin, Micah A Johnson, Ying-Hui Chou, Guy G Potter, Nan-Kuei Chen, Lauren E Packard, Rachel E Siciliano, Zachary A Monge, Michele T Diaz
We conducted functional magnetic resonance imaging (fMRI) with a visual search paradigm to test the hypothesis that aging is associated with increased frontoparietal involvement in both target detection and bottom-up attentional guidance (featural salience). Participants were 68 healthy adults, distributed continuously across 19 to 78 years of age. Frontoparietal regions of interest (ROIs) were defined from resting-state scans obtained prior to task-related fMRI. The search target was defined by a conjunction of color and orientation...
April 2017: Human Brain Mapping
https://www.readbyqxmd.com/read/27998227/optimizing-the-use-of-gene-expression-profiling-in-early-stage-breast-cancer
#17
Hyun-Seok Kim, Christopher B Umbricht, Peter B Illei, Ashley Cimino-Mathews, Soonweng Cho, Nivedita Chowdhury, Maria Cristina Figueroa-Magalhaes, Catherine Pesce, Stacie C Jeter, Charles Mylander, Martin Rosman, Lorraine Tafra, Bradley M Turner, David G Hicks, Tyler A Jensen, Dylan V Miller, Deborah K Armstrong, Roisin M Connolly, John H Fetting, Robert S Miller, Ben Ho Park, Vered Stearns, Kala Visvanathan, Antonio C Wolff, Leslie Cope
Purpose Gene expression profiling assays are frequently used to guide adjuvant chemotherapy decisions in hormone receptor-positive, lymph node-negative breast cancer. We hypothesized that the clinical value of these new tools would be more fully realized when appropriately integrated with high-quality clinicopathologic data. Hence, we developed a model that uses routine pathologic parameters to estimate Oncotype DX recurrence score (ODX RS) and independently tested its ability to predict ODX RS in clinical samples...
December 20, 2016: Journal of Clinical Oncology: Official Journal of the American Society of Clinical Oncology
https://www.readbyqxmd.com/read/27975270/controlling-the-messenger-regulated-translation-of-maternal-mrnas-in-xenopus-laevis-development
#18
Michael D Sheets, Catherine A Fox, Megan E Dowdle, Susanne Imboden Blaser, Andy Chung, Sookhee Park
The selective translation of maternal mRNAs encoding cell-fate determinants drives the earliest decisions of embryogenesis that establish the vertebrate body plan. This chapter will discuss studies in Xenopus laevis that provide insights into mechanisms underlying this translational control. Xenopus has been a powerful model organism for many discoveries relevant to the translational control of maternal mRNAs because of the large size of its oocytes and eggs that allow for microinjection of molecules and the relative ease of manipulating the oocyte to egg transition (maturation) and fertilization in culture...
2017: Advances in Experimental Medicine and Biology
https://www.readbyqxmd.com/read/27918777/global-regional-and-national-cancer-incidence-mortality-years-of-life-lost-years-lived-with-disability-and-disability-adjusted-life-years-for-32-cancer-groups-1990-to-2015-a-systematic-analysis-for-the-global-burden-of-disease-study
#19
Christina Fitzmaurice, Christine Allen, Ryan M Barber, Lars Barregard, Zulfiqar A Bhutta, Hermann Brenner, Daniel J Dicker, Odgerel Chimed-Orchir, Rakhi Dandona, Lalit Dandona, Tom Fleming, Mohammad H Forouzanfar, Jamie Hancock, Roderick J Hay, Rachel Hunter-Merrill, Chantal Huynh, H Dean Hosgood, Catherine O Johnson, Jost B Jonas, Jagdish Khubchandani, G Anil Kumar, Michael Kutz, Qing Lan, Heidi J Larson, Xiaofeng Liang, Stephen S Lim, Alan D Lopez, Michael F MacIntyre, Laurie Marczak, Neal Marquez, Ali H Mokdad, Christine Pinho, Farshad Pourmalek, Joshua A Salomon, Juan Ramon Sanabria, Logan Sandar, Benn Sartorius, Stephen M Schwartz, Katya A Shackelford, Kenji Shibuya, Jeff Stanaway, Caitlyn Steiner, Jiandong Sun, Ken Takahashi, Stein Emil Vollset, Theo Vos, Joseph A Wagner, Haidong Wang, Ronny Westerman, Hajo Zeeb, Leo Zoeckler, Foad Abd-Allah, Muktar Beshir Ahmed, Samer Alabed, Noore K Alam, Saleh Fahed Aldhahri, Girma Alem, Mulubirhan Assefa Alemayohu, Raghib Ali, Rajaa Al-Raddadi, Azmeraw Amare, Yaw Amoako, Al Artaman, Hamid Asayesh, Niguse Atnafu, Ashish Awasthi, Huda Ba Saleem, Aleksandra Barac, Neeraj Bedi, Isabela Bensenor, Adugnaw Berhane, Eduardo Bernabé, Balem Betsu, Agnes Binagwaho, Dube Boneya, Ismael Campos-Nonato, Carlos Castañeda-Orjuela, Ferrán Catalá-López, Peggy Chiang, Chioma Chibueze, Abdulaal Chitheer, Jee-Young Choi, Benjamin Cowie, Solomon Damtew, José das Neves, Suhojit Dey, Samath Dharmaratne, Preet Dhillon, Eric Ding, Tim Driscoll, Donatus Ekwueme, Aman Yesuf Endries, Maryam Farvid, Farshad Farzadfar, Joao Fernandes, Florian Fischer, Tsegaye Tewelde G/Hiwot, Alemseged Gebru, Sameer Gopalani, Alemayehu Hailu, Masako Horino, Nobuyuki Horita, Abdullatif Husseini, Inge Huybrechts, Manami Inoue, Farhad Islami, Mihajlo Jakovljevic, Spencer James, Mehdi Javanbakht, Sun Ha Jee, Amir Kasaeian, Muktar Sano Kedir, Yousef S Khader, Young-Ho Khang, Daniel Kim, James Leigh, Shai Linn, Raimundas Lunevicius, Hassan Magdy Abd El Razek, Reza Malekzadeh, Deborah Carvalho Malta, Wagner Marcenes, Desalegn Markos, Yohannes A Melaku, Kidanu G Meles, Walter Mendoza, Desalegn Tadese Mengiste, Tuomo J Meretoja, Ted R Miller, Karzan Abdulmuhsin Mohammad, Alireza Mohammadi, Shafiu Mohammed, Maziar Moradi-Lakeh, Gabriele Nagel, Devina Nand, Quyen Le Nguyen, Sandra Nolte, Felix A Ogbo, Kelechi E Oladimeji, Eyal Oren, Mahesh Pa, Eun-Kee Park, David M Pereira, Dietrich Plass, Mostafa Qorbani, Amir Radfar, Anwar Rafay, Mahfuzar Rahman, Saleem M Rana, Kjetil Søreide, Maheswar Satpathy, Monika Sawhney, Sadaf G Sepanlou, Masood Ali Shaikh, Jun She, Ivy Shiue, Hirbo Roba Shore, Mark G Shrime, Samuel So, Samir Soneji, Vasiliki Stathopoulou, Konstantinos Stroumpoulis, Muawiyyah Babale Sufiyan, Bryan L Sykes, Rafael Tabarés-Seisdedos, Fentaw Tadese, Bemnet Amare Tedla, Gizachew Assefa Tessema, J S Thakur, Bach Xuan Tran, Kingsley Nnanna Ukwaja, Benjamin S Chudi Uzochukwu, Vasiliy Victorovich Vlassov, Elisabete Weiderpass, Mamo Wubshet Terefe, Henock Gebremedhin Yebyo, Hassen Hamid Yimam, Naohiro Yonemoto, Mustafa Z Younis, Chuanhua Yu, Zoubida Zaidi, Maysaa El Sayed Zaki, Zerihun Menlkalew Zenebe, Christopher J L Murray, Mohsen Naghavi
Importance: Cancer is the second leading cause of death worldwide. Current estimates on the burden of cancer are needed for cancer control planning. Objective: To estimate mortality, incidence, years lived with disability (YLDs), years of life lost (YLLs), and disability-adjusted life-years (DALYs) for 32 cancers in 195 countries and territories from 1990 to 2015. Evidence Review: Cancer mortality was estimated using vital registration system data, cancer registry incidence data (transformed to mortality estimates using separately estimated mortality to incidence [MI] ratios), and verbal autopsy data...
December 3, 2016: JAMA Oncology
https://www.readbyqxmd.com/read/27899635/interpro-in-2017-beyond-protein-family-and-domain-annotations
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Robert D Finn, Teresa K Attwood, Patricia C Babbitt, Alex Bateman, Peer Bork, Alan J Bridge, Hsin-Yu Chang, Zsuzsanna Dosztányi, Sara El-Gebali, Matthew Fraser, Julian Gough, David Haft, Gemma L Holliday, Hongzhan Huang, Xiaosong Huang, Ivica Letunic, Rodrigo Lopez, Shennan Lu, Aron Marchler-Bauer, Huaiyu Mi, Jaina Mistry, Darren A Natale, Marco Necci, Gift Nuka, Christine A Orengo, Youngmi Park, Sebastien Pesseat, Damiano Piovesan, Simon C Potter, Neil D Rawlings, Nicole Redaschi, Lorna Richardson, Catherine Rivoire, Amaia Sangrador-Vegas, Christian Sigrist, Ian Sillitoe, Ben Smithers, Silvano Squizzato, Granger Sutton, Narmada Thanki, Paul D Thomas, Silvio C E Tosatto, Cathy H Wu, Ioannis Xenarios, Lai-Su Yeh, Siew-Yit Young, Alex L Mitchell
InterPro (http://www.ebi.ac.uk/interpro/) is a freely available database used to classify protein sequences into families and to predict the presence of important domains and sites. InterProScan is the underlying software that allows both protein and nucleic acid sequences to be searched against InterPro's predictive models, which are provided by its member databases. Here, we report recent developments with InterPro and its associated software, including the addition of two new databases (SFLD and CDD), and the functionality to include residue-level annotation and prediction of intrinsic disorder...
January 4, 2017: Nucleic Acids Research
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