podagra

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No abstract text is available yet for this article.

Although the classic location of gouty tophi is the great toe (podagra), gouty tophi of the ear also is common and is worth including in the differential diagnosis in patients presenting with ear lesions. Other entities presenting as papules or nodules on the ear include chondrodermatitis nodularis helicis (CNH), actinic keratosis, basal cell carcinoma, squamous cell carcinoma, verruca vulgaris, amyloids, rheumatoid nodules, and elastotic nodules. If tophaceous gout is suspected, alcohol fixation of the biopsy specimen is preferable, as it enables visualization of characteristic needle-shaped urate crystals...

The foot is the target organ of a variety of internal diseases. Of upmost importance is the diabetic foot syndrome (DFS). Its complex pathophysiology is driven by the diabetic neuropathy, a vastly worsening effect is contributed by infection and ischemia. Seemingly localised lesions have the potential for phlegmone and septicaemia if not diagnosed and drained early. The acral lesions of peripheral artery occlusive disease (PAOD) have unique features as well. However, their life-threatening potential is lower than that of DFS even if the limb is critical...

SESSION TYPE: Airway Student/Resident Case Report PostersPRESENTED ON: Tuesday, October 23, 2012 at 01:30 PM - 02:30 PMINTRODUCTION: Joint disease affecting adults with Cystic Fibrosis (CF) may present as episodic arthritis and/or hypertrophic pulmonary osteoarthropathy (HPOA). Gout is rarely reported in adults with CF. We report an adult CF patient who presented to us with Podagra.CASE PRESENTATION: A thirty year old white man with CF presented with severe pain in left big toe and redness for one week. He denied trauma to left foot...

OBJECTIVE: We sought to examine primary care providers' gout knowledge and reported treatment patterns in comparison with current treatment recommendations. METHODS: We conducted a national survey of a random sample of US primary care physicians to assess their treatment of acute, intercritical and tophaceous gout using published European and American gout treatment recommendations and guidelines as a gold standard. RESULTS: There were 838 respondents (response rate of 41%), most of whom worked in private practice (63%) with >16 years experience (52%)...

Gout is an ancient disease. Despite significant advances in the understanding of its risk factors, etiology, pathogenesis, prevention, and treatment, millions of people with gout experience repeated attacks of acute arthritis and other complications. The incidence of gout is increasing, most likely reflecting increasing rates of obesity and other lifestyle factors, including diet. Comorbid conditions that often accompany gout, including chronic kidney disease and diabetes mellitus, present challenges for the management of gout...

The prevalence of gout increases with age. Up to 7% of men > 65 and 3% of women > 85 have gout. Risk of gout increases significantly with increasing serum uric acid levels. Alcohol consumption and purine-rich foods such as red meat and seafood increase the risk of incident gout significantly. Loop and thiazide diuretics are also associated with increased risk. Gout is frequently associated with the metabolic syndrome. Dehydration, increasing creatinine levels, and surgery are also known to precipitate flares...

Gout is an often-overlooked and undertreated inflammatory arthritis that is most frequently managed in the primary care office. Its initial clinical presentation may include acute-onset pain that is most typically associated with the big toe (podagra) or knee. Most patients with gout can be successfully treated from the primary care physician's office with little or no need for referral to a rheumatology practice. Prompt recognition, diagnosis, and management can greatly improve the lives of patients with gout...

The purpose of this study is to determine the diagnostic properties of the clinical gout diagnosis (CGD) proposal in patients with gout and other rheumatic diseases. We investigated the presence of current or past history of the previously published CGD criteria: (1) >1 attack of acute arthritis, (2) mono/oligoarthritis attacks, (3) rapid progression of pain and swelling (<24 h), (4) podagra, (5) erythema, (6) unilateral tarsitis, (7) probable tophi, and (8) hyperuricemia. CGD was established in patients with greater than or equal to four out of eight of these criteria...

Crystal-induced arthritis (CIA) is easy to diagnose as soon as the physician might suspect the diagnosis. Indeed, CIA can be readily ascertained since one single gold standard is available: identification of microcrystals in synovial fluid or in other materials (tophus, synovial tissue biopsy, periarticular tissues). It is therefore mandatory to perform joint aspiration and to get synovial fluid sample for microscopic examination. Monosodium urate crystals are the key feature of gout, and calcium pyrophosphate (CPP) crystals are associated with CPP disease, also called "chondrocalcinosis" in France...

Joint diseases in antiquity and the Renaissance were generally known by the all-encompassing term, gout (podagra or gotta). Only in later centuries was there a differentiation in the types of joint diseases, distinguishing gout in the modern sense from other arthritic and rheumatic disorders. The present article illustrates one pictorial representation of joint disease from the early sixteenth century, a case that seems typical of gouty tophi.

This invited paper provides a summary of a keynote lecture delivered at the 2011 Australasian Podiatry Conference. Gout is the most prevalent inflammatory arthropathy. It displays a striking predilection to affect the first metatarsophalangeal joint as well as joints within the mid-foot and ankle. A number of factors are known to reduce urate solubility and enhance nucleation of monosodium urate crystals including decreased temperature, lower pH and physical shock, all of which may be particularly relevant to crystal deposition in the foot...

Clinically, gout is generally considered as a preferential male disease. However, it definitely does not occur exclusively in males. Our aim was to assess differences in the clinical features of gout arthritis between female and male patients. Five electronic databases were searched to identify relevant original studies published between 1977 and 2007. The included studies had to focus on adult patients with primary gout arthritis and on sex differences in clinical features. Two reviewers independently assessed eligibility and quality of the studies...

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Inscriptions of Sanationes from Sanctuaries of god Asclepius, testifying to the gratitude of patients to the divinity, present a situation, albeit fragmentary, of main diseases which physicians thought incurable or hardly curable. Sterility, calvities, worms, paralysis, as well as clinical disorders caused by rheuma appear, along with gout/podagra, in many inscriptions too. To counter them, patients asked for the intervention of Asclepius.

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The majority of patients with gout are cared for by primary care physicians. Although both the physician and patient may easily recognize the acute arthritis of gout, errors in selecting the most appropriate medication and proper dose are common. The clinical stages of gout include asymptomatic hyperuricemia, intermittent gouty arthritis, and chronic tophaceous gout. Treatment of gout is usually considered after the first attack of arthritis, typically podagra. The aims of treatment are to alleviate the pain and inflammation associated with acute attacks, prevent future attacks, and decrease uric acid levels...

Insteroidic antiphlogistic medicines occupies significant segment on pharmacy market. They have been in clinical practice since 1980-es, and are still widely used in treatment of systemic collagenous; myalgia; radiculitis, bursitis, arthritis, podagra and etc. To display the tendency of market development - the goal of the research - we studied the demand and supply in insteroidic antiphlogistic medicines in Kutaisi. The assortments in retail chemist's shops was studied. We also studied price lists and questionnaires of wholesale pharmacy institutions and requirements for the following medicines: aspirin, paracetamol, indometacin, diclophenak, ketoprofen, naproxen, meloksikam, nimesulid, piroksikam...