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https://www.readbyqxmd.com/read/29045341/effect-of-antihypertensive-treatment-on-24-h-blood-pressure-variability-pooled-individual-data-analysis-of-ambulatory-blood-pressure-monitoring-studies-based-on-olmesartan-mono-or-combination-treatment
#1
Stefano Omboni, Kazuomi Kario, George Bakris, Gianfranco Parati
OBJECTIVE: To evaluate the impact of olmesartan alone or combined with one to three antihypertensive drugs on 24-h blood pressure variability (BPV) and on distribution of BP reduction in a pooled individual data analysis of 10 double-blind, randomized, ambulatory BP monitoring (ABPM) studies. METHODS: ABPMs were performed before and after 6-12 weeks of treatment with placebo (n = 119), active control monotherapy [n = 1195, angiotensin-converting enzyme inhibitors (ACEIs), angiotensin II receptor blockers (ARBs), dihydropyridine calcium channel blockers (DCCBs)], or DCCBs), olmesartan monotherapy (n = 1410), active control dual combination [n = 79, DCCB + thiazide diuretic (TD)], olmesartan dual combination (n = 637, DCCB or TD), and triple combination therapy (n = 102, DCCB+TD)...
October 16, 2017: Journal of Hypertension
https://www.readbyqxmd.com/read/29043559/nonfunctioning-adrenal-incidentaloma-affecting-central-blood-pressure-and-arterial-stiffness-parameters
#2
Tolga Akkan, Mustafa Altay, Yasemin Ünsal, Murat Dağdeviren, Esin Beyan
PURPOSE: Recently, cardiovascular risk is thought to be increased in patients with nonfunctioning adrenal incidentaloma (NFAI). There are no sufficient studies in the literature to evaluate this situation in NFAI patients without cardiovascular risk. The objective of this study is to compare peripheral and central blood pressure and arterial stiffness between patients with NFAI and healthy volunteers (of a similar age, gender and body mass index as the NFAI group) who have no traditional cardiovascular risk factors and autonomous cortisol secretion, with pulse wave analysis (PWA)...
October 17, 2017: Endocrine
https://www.readbyqxmd.com/read/29040398/correlation-of-blood-pressure-variability-as-measured-by-clinic-self-measurement-at-home-and-ambulatory-blood-pressure-monitoring
#3
J Abellán-Huerta, L Prieto-Valiente, S Montoro-García, J Abellán-Alemán, F Soria-Arcos
Background: Blood pressure variability (BPV) has been postulated as a potential predictor of cardiovascular outcomes. No agreement exists as to which measurement method is best for BPV estimation. We attempt to assess the correlation between BPV obtained at the doctor's office, self-measurement at home (SMBP) and ambulatory BP monitoring (ABPM). Methods: Eight weekly clinic BP measurements, two SMBP series and one 24-hour ABPM recording were carried out in a sample of treated hypertensive patients...
October 10, 2017: American Journal of Hypertension
https://www.readbyqxmd.com/read/29033973/comparison-of-central-ambulatory-home-and-office-blood-pressure-measurement-as-risk-markers-for-mild-cognitive-impairment-in-hypertensive-patients
#4
Teodora Yaneva-Sirakova, Latchezar Traykov, Julia Petrova, Dobrin Vassilev
AIMS: We compared the role of central blood pressure (BP), ambulatory BP monitoring (ABPM), home-measured BP (HMBP) and office BP measurement as risk markers for the development of mild cognitive impairment (MCI). METHODS: 70 hypertensive patients on combination medical therapy were studied. Their mean age was 64.97 ± 8.88 years. Eighteen (25.71%) were males and 52 (74.28%) females. All of the patients underwent full physical examination, laboratory screening, echocardiography, and office, ambulatory, home and central BP measurement...
May 2017: Dementia and Geriatric Cognitive Disorders Extra
https://www.readbyqxmd.com/read/29033414/spontaneous-regression-of-allergic-bronchopulmonary-mycosis-due-to-curvularia-lunata
#5
Shingo Nasu, Shingo Satoh, Kazunori Shimizu, Osamu Matsuno, Hiroshi Morishita, Takashi Yaguchi, Kunimitsu Kawahara, Hiroto Matsuoka
Allergic bronchopulmonary mycosis (ABPM) is a pulmonary hypersensitivity disease mainly caused by Aspergillus fumigatus. The mainstay treatment for ABPM is systemic corticosteroid therapy. A 25-year-old man presented with pulmonary infiltrates. His peripheral eosinophil, total serum IgE, and serum Aspergillus-specific IgE levels were elevated. The patient tested positive in a skin test for Aspergillus. However, sputum cultures revealed a Curvularia lunata infection. We therefore diagnosed ABPM possibly caused by C...
October 16, 2017: Internal Medicine
https://www.readbyqxmd.com/read/29020251/differential-blood-pressure-effects-of-ibuprofen-naproxen-and-celecoxib-in-patients-with-arthritis-the-precision-abpm-prospective-randomized-evaluation-of-celecoxib-integrated-safety-versus-ibuprofen-or-naproxen-ambulatory-blood-pressure-measurement-trial
#6
Frank Ruschitzka, Jeffrey S Borer, Henry Krum, Andreas J Flammer, Neville D Yeomans, Peter Libby, Thomas F Lüscher, Daniel H Solomon, M Elaine Husni, David Y Graham, Deborah A Davey, Lisa M Wisniewski, Venu Menon, Rana Fayyad, Bruce Beckerman, Dinu Iorga, A Michael Lincoff, Steven E Nissen
Aims: Non-steroidal anti-inflammatory drugs (NSAIDs), both non-selective and selective cyclooxygenase-2 (COX-2) inhibitors, are among the most widely prescribed drugs worldwide, but associate with increased blood pressure (BP) and adverse cardiovascular (CV) events. PRECISION-ABPM, a substudy of PRECISION was conducted at 60 sites, to determine BP effects of the selective COX-2 inhibitor celecoxib vs. the non-selective NSAIDs naproxen and ibuprofen. Methods and results: In this double-blind, randomized, multicentre non-inferiority CV-safety trial, 444 patients (mean age 62 ± 10 years, 54% female) with osteoarthritis (92%) or rheumatoid arthritis (8%) and evidence of or at increased risk for coronary artery disease received celecoxib (100-200 mg bid), ibuprofen (600-800 mg tid), or naproxen (375-500 mg bid) with matching placebos in a 1: 1: 1 allocation, to assess the effect on 24-h ambulatory BP after 4 months...
August 28, 2017: European Heart Journal
https://www.readbyqxmd.com/read/29018827/low-levels-of-usual-physical-activity-are-associated-with-higher-24%C3%A2-h-blood-pressure-in-type-2-diabetes-mellitus-in-a-cross-sectional-study
#7
Alessandra Teixeira Neto Zucatti, Tatiana Pedroso de Paula, Luciana Verçoza Viana, Rafael DallAgnol, Felipe Vogt Cureau, Mirela Jobim Azevedo, Jorge Luiz Gross, Beatriz D Schaan, Cristiane Bauermann Leitao
The aim of this study is to evaluate the association between usual physical activity and 24 h blood pressure (BP) profile in people with type 2 diabetes mellitus (DM). This is a cross-sectional study of 151 participants with type 2 DM. Usual physical activity was assessed by step counting and self-reported questionnaire. BP was measured in office and by 24 h ambulatory BP monitoring (ABPM; 24 h, daytime and nighttime). Mean participant age was 61.1 ± 8.4 years, 64% was women, and mean duration of diabetes was 14...
2017: Journal of Diabetes Research
https://www.readbyqxmd.com/read/28992284/plasma-homocysteine-levels-are-associated-with-circadian-blood-pressure-variation-in-chinese-hypertensive-adults
#8
Yi-Fei Dong, Bi-Ming Zhan, Qing-Yun Hao, Zhao-Hui Ruan, Zi-Xuan Xu, Ming Deng, Da-Wei Chen, Ye-Qing Zou, Jing Chen, Ping Li, Xiao-Shu Cheng
BACKGROUND: Homocysteine-lowering intervention with folate was recently shown to be able to increase day-night difference of blood pressure (BP) in humans indicating a potential relationship between homocysteine and circadian BP variation. We thus sought to investigate the association between plasma total homocysteine level (tHcy) and circadian BP variation in hypertensive adults. METHODS: We enrolled 244 eligible dipping and 249 nondipping BP status adults from 560 adults who were randomly sampled from 5,233 Chinese hypertensive adults who received ambulatory BP monitoring (ABPM)...
July 11, 2017: American Journal of Hypertension
https://www.readbyqxmd.com/read/28985342/the-effect-of-head-and-neck-radiotherapy-on-blood-pressure-and-orthostatic-hypotension-in-patients-with-head-and-neck-tumors
#9
Avshalom Leibowitz, Ehud Grossman, Anat Berkovitch, Meital Levartovski, Sarit Appel, Yehonatan Sharabi, Iris Gluck
Background: Radiotherapy (RT) plays a key role in the management of head and neck cancer (HNC), especially in locally advanced disease. Patients undergoing head and neck RT, especially elderly ones, are suffering from low and labile blood pressure (BP) during the treatment. They complain of weakness and fatigue and are prone to recurrent falls. The aim of this study was to characterized BP changes during RT period. Methods: Patients with HNC, recieving radiation to the neck, were recruited from Sheba medical center RT unit...
August 29, 2017: American Journal of Hypertension
https://www.readbyqxmd.com/read/28982776/blood-pressure-response-to-cpap-treatment-in-subjects-with-obstructive-sleep-apnoea-the-predictive-value-of-24-h-ambulatory-blood-pressure-monitoring
#10
Anabel L Castro-Grattoni, Gerard Torres, Montserrat Martínez-Alonso, Ferran Barbé, Cecilia Turino, Alicia Sánchez-de-la-Torre, Anunciacion Cortijo, Joaquin Duran-Cantolla, Carlos Egea, Gonzalo Cao, Manuel Sánchez-de-la-Torre
The reduction in blood pressure (BP) with continuous positive airway pressure (CPAP) is modest and highly variable. In this study, we identified the variables that predict BP response to CPAP.24-h ambulatory BP monitoring (ABPM), C-reactive protein (CRP), leptin, adiponectin and 24-h urinary catecholamine were measured before and after 6 months of CPAP in obstructive sleep apnoea (OSA) patients.Overall, 88 middle-aged, obese male patients with severe OSA (median apnoea-hypopnoea index 42 events·h(-1)) were included; 28...
October 2017: European Respiratory Journal: Official Journal of the European Society for Clinical Respiratory Physiology
https://www.readbyqxmd.com/read/28958009/masked-hypertension-is-associated-with-cognitive-decline-in-geriatric-age-g-mash-cog-study-geriatric-masked-hypertension-and-cognition
#11
Mert Esme, Burcu Balam Yavuz, Bunyamin Yavuz, Serkan Asil, Rana Tuna Dogrul, Fatih Sumer, Mustafa Kemal Kilic, Muhammet Cemal Kizilarslanoglu, Hacer Dogan Varan, Aykut Sagir, Cafer Balci, Meltem Halil, Mustafa Cankurtaran
Background: Masked hypertension is described as high ambulatory blood pressure measurements (ABPM) where office blood pressure measurements are normal. Effect of hypertension on cognitive functions is well known. However, the effect of masked hypertension on cognitive functions is unclear. The aim of this study is to examine the relationship between masked hypertension and cognitive functions. Methods: One hundred-two normotensive patients admitted to the Geriatric Medicine outpatient clinic were included...
August 8, 2017: Journals of Gerontology. Series A, Biological Sciences and Medical Sciences
https://www.readbyqxmd.com/read/28935634/assessment-of-left-ventricular-function-and-peripheral-vascular-arterial-stiffness-in-patients-with-dipper-and-non-dipper-hypertension
#12
Yan Chen, Ju-Hua Liu, Zhe Zhen, Yuan Zuo, Qingshan Lin, Mingya Liu, Chunting Zhao, Min Wu, Gaozhen Cao, Run Wang, Hung-Fat Tse, Kai-Hang Yiu
A non-dipper pattern of high blood pressure is associated with increased risk of organ damage and cardiovascular disease in patients with hypertension. The aim of the study was to evaluate the left ventricular (LV) remodeling and function and arterial stiffness in a dipper/non-dipper pattern of high blood pressure in patients with hypertension. A total of 183 hypertensive patients with no history of adverse cardiovascular events were divided into two groups based on 24 hours ambulatory blood pressure monitoring (ABPM): 66 patients with a dipper pattern and 117 patients with non-dipper pattern...
September 20, 2017: Journal of Investigative Medicine: the Official Publication of the American Federation for Clinical Research
https://www.readbyqxmd.com/read/28935191/circadian-rhythm-and-autonomic-dysfunction-in-presymptomatic-and-early-huntington-s-disease
#13
Elena Bellosta Diago, Jesús Pérez Pérez, Sonia Santos Lasaosa, Alejandro Viloria Alebesque, Saül Martínez Horta, Jaime Kulisevsky, Javier López Del Val
INTRODUCTION: Sleep and circadian rhythm disturbances are common in patients with neurodegenerative diseases such as Huntington's disease (HD). The aim of this study was to evaluate variability in circadian blood pressure (BP) to determine the association between abnormal circadian BP and sleep quality in patients with HD. METHODS: Cross-sectional, multicenter study of 38 HD mutation carriers (23 premanifest and 15 early stage patients) who were compared to 38 age- and sex-matched controls...
September 15, 2017: Parkinsonism & related Disorders
https://www.readbyqxmd.com/read/28914629/association-between-ambulatory-blood-pressure-values-and-central-aortic-pressure-in-a-large-population-of-normotensive-and-hypertensive-patients
#14
Ana Rouxinol-Dias, Sara Araújo, José A Silva, Loide Barbosa, Jorge Polónia
OBJECTIVE: Our aim was to examine the association of ambulatory blood pressure monitoring (ABPM) and central blood pressure (CBP) data in a large set of normotensive and hypertensive patients and its relation with pulse wave velocity (PWV). PATIENTS AND METHODS: This cross-sectional study was carried out in a single centre and included 2864 individuals who carried out an ABPM, measurement of CBP from the aortic waveform (SphygmoCor) and carotid-femoral PWV (Complior)...
September 13, 2017: Blood Pressure Monitoring
https://www.readbyqxmd.com/read/28911024/ambulatory-pulse-pressure-predicts-the-development-of-left-ventricular-diastolic-dysfunction-in-over-20-years-of-follow-up
#15
Tero J W Pääkkö, Reko J Renko, Juha S Perkiömäki, Y Antero Kesäniemi, Antti S Ylitalo, Jarmo A Lumme, Heikki V Huikuri, Heikki Ruskoaho, Olli Vuolteenaho, Olavi H Ukkola
BACKGROUND: Ambulatory blood pressure (ABP) has been shown to have an association with left ventricular diastolic dysfunction (LVDD) in cross-sectional assessments. We evaluated the association between ABP measurement (ABPM) and the development of LVDD during over 20 years of follow up in 414 middle-aged subjects from OPERA cohort. METHODS: ABPM, clinical, and anthropometric measurements were performed in baseline. Echocardiographic measurements were performed at baseline and during follow-up and E/E' ≥15 was considered indicating significant LVDD...
October 1, 2017: American Journal of Hypertension
https://www.readbyqxmd.com/read/28904878/the-effects-of-different-physical-activities-on-atrial-fibrillation-in-patients-with-hypertension-and-chronic-kidney-disease
#16
Márcio Galindo Kiuchi, Shaojie Chen, Neil Alexander Hoye
BACKGROUND: Atrial fibrillation (AF) is highly common, and is most frequently observed in individuals with hypertension and structural cardiac disease. Sympathetic hyperactivity plays a fundamental role in the progression, maintenance and aggravation of arrhythmia. Endurance exercise training clearly lowers sympathetic activity in sympathoexcitatory disease states, and is well-tolerated by patients with chronic kidney disease (CKD). METHODS: We assessed 50 CKD patients with hypertension...
September 2017: Kidney Research and Clinical Practice
https://www.readbyqxmd.com/read/28886852/prevalence-of-hypertension-in-professional-drivers-from-the-racer-abpm-study
#17
Anna E Platek, Filip M Szymanski, Krzysztof J Filipiak, Marcin Kotkowski, Anna Rys, Karolina Semczuk-Kaczmarek, Karolina Adamkiewicz
Professional drivers are a group exposed to many cardiovascular risk factors. Nonsystematic working hours, stress, low physical activity, and unhealthy dietary habits are common among professional drivers. These translate into high risk of cardiovascular disease. The aim of the current analysis was to establish the prevalence of arterial hypertension in a group of continuous professional drivers. The RACER (Risk of Adverse Cardiovascular Events among professional dRivers in Poland) study is a prospective study focused on assessing cardiovascular risk factors in professional drivers...
August 8, 2017: American Journal of Cardiology
https://www.readbyqxmd.com/read/28876375/twenty-four-hour-blood-pressure-in-obese-patients-with-moderate-to-severe-obstructive-sleep-apnea
#18
Claudia M Correa, Ronaldo A Gismondi, Ana Rosa Cunha, Mario F Neves, Wille Oigman
BACKGROUND: Obesity, systemic arterial hypertension (SAH) and obstructive sleep apnea (OSA) are closely related. Up to 70% of patients with OSA may be asymptomatic, and there is evidence that these patients have cardiovascular disease, especially nocturnal SAH. OBJECTIVES: The aim of this study was to evaluate 24-hour blood pressure circadian variation in asymptomatic, obese individuals with moderate-to-severe OSA and compare it with that in individuals with mild OSA or without OSA...
September 4, 2017: Arquivos Brasileiros de Cardiologia
https://www.readbyqxmd.com/read/28870547/association-of-ambulatory-blood-pressure-monitoring-parameters-with-the-framingham-stroke-risk-profile
#19
Georgios Tsivgoulis, Maria Pikilidou, Aristeidis H Katsanos, Kimon Stamatelopoulos, Fotios Michas, Aikaterini Lykka, Christina Zompola, Angeliki Filippatou, Efstathios Boviatsis, Konstantinos Voumvourakis, Nikolaos Zakopoulos, Efstathios Manios
The Framingham Stroke Risk Profile (FSRP) is a novel and reliable tool for estimating the 10-year probability for incident stroke in stroke-free individuals, while the predictive value of ambulatory blood pressure monitoring (ABPM) for first-ever and recurrent stroke has been well established. We sought to evaluate cross-sectionally the association of ABPM parameters with FSRP score in a large sample of 2343 consecutive stroke-free individuals (mean age: 56.0±12.9, 49.1% male) who underwent 24-hour ABPM. True hypertensives showed significantly higher FSRP (11...
September 15, 2017: Journal of the Neurological Sciences
https://www.readbyqxmd.com/read/28865784/bedtime-chronotherapy-with-conventional-hypertension-medications-to-target-increased-asleep-blood-pressure-results-in-markedly-better-chronoprevention-of-cardiovascular-and-other-risks-than-customary-on-awakening-therapy
#20
REVIEW
Michael H Smolensky, Ramón C Hermida, Diana E Ayala, Artemio Mojón, José R Fernández
The bases for bedtime hypertension chronotherapy (BHCT) as superior chronoprevention against cardiovascular disease (CVD) are: (1) correlation between blood pressure (BP) and various risks is greater for ambulatory BP monitoring (ABPM) than office BP measurements (OBPM); (2) asleep BP mean is a better predictor of CVD risk than ABPM awake and 24-hour means and OBPM; and (3) targeting of asleep BP by BHCT with one or more conventional medications versus usual on-awakening therapy better reduces major and total CVD events...
October 2017: Heart Failure Clinics
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