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https://www.readbyqxmd.com/read/29332433/slippage-of-tightrope-button-in-syndesmotic-fixation-of-weber-c-malleolar-fractures-a-case-series
#1
Mas'uud Ibnu Samsudin, Ming Quan Wayne Yap, Ang Wei Luong, Ernest Beng Kee Kwek
BACKGROUND: Tightrope fixation is an emerging technique for syndesmotic fixation with promising results. However, our case series highlights the slippage of Tightrope buttons as a complication of suture button syndesmotic fixation of Weber C malleolar fractures using limited contact dynamic compression (LCDCP) plates. METHODS: We report a series of cases from our database in which slippage of the Tightrope button through the LCDCP holes in Weber C malleolar fractures was noted...
January 1, 2018: Foot & Ankle International
https://www.readbyqxmd.com/read/29303021/therapeutic-effect-of-acetazolamide-an-aquaporin-1-inhibitor-on-adjuvant-induced-arthritis-in-rats-by-inhibiting-nf-%C3%AE%C2%BAb-signal-pathway
#2
Li Cai, Wei-Na Chen, Rong Li, Cheng-Mu Hu, Chao Lei, Chun-Mei Li
OBJECTIVES: Previous studies have shown that aquaporin 1 (AQP1) is up-regulated in synovium and cartilage of rheumatoid arthritis (RA) patients and that AQP1 may be involved in joint swelling and synovial inflammation. This study was aimed to investigate the potential therapeutic effect of acetazolamide (AZ, an AQP1 inhibitor) on rat adjuvant-induced arthritis (AIA) and explore its related mechanisms. MATERIALS AND METHODS: Rat AIA was induced by complete Freund's adjuvant...
January 5, 2018: Immunopharmacology and Immunotoxicology
https://www.readbyqxmd.com/read/29274315/clinical-tests-have-limited-predictive-value-for-chronic-ankle-instability-when-conducted-in-the-acute-phase-of-a-first-time-lateral-ankle-sprain-injury
#3
Cailbhe Doherty, Chris Bleakley, Jay Hertel, Brian Caulfield, John Ryan, Eamonn Delahunt
OBJECTIVE: To evaluate whether a battery of clinical assessments for acute lateral ankle sprain (LAS) can be used to predict long-term recovery. DESIGN: Cohort study SETTING: University biomechanics laboratory PARTICIPANTS: Eighty-two individuals were assessed using a clinical test battery within two-weeks of incurring a first-time LAS. MAIN OUTCOME MEASURES: The clinical test battery included scores on the 'talar-glide' (deg), anterior-drawer, talar-tilt, figure-of-eight [figure8] for swelling (mm), knee-to-wall (mm) and hand-held goniometric range-of-motion [inversion; eversion; plantar-flexion (in degrees)]...
December 20, 2017: Archives of Physical Medicine and Rehabilitation
https://www.readbyqxmd.com/read/29259651/a-case-of-painful-ankle-swelling-cytomorphological-clues-and-pitfalls
#4
Biswajit Dey, Archana Hemant Deshpande, Pushpanjali Ojha, Chitrawati Bal Gargade, Jitendra Singh Nigam, Amit Ray
No abstract text is available yet for this article.
2017: CytoJournal
https://www.readbyqxmd.com/read/29244676/severe-metal-hypersensitivity-following-internal-fixation-of-an-ankle-fracture-a-case-report
#5
Bradley M Kruckeberg, Taylor J Ridley, Lee M Reichel
CASE: A 67-year-old woman underwent internal fixation of an ankle fracture. Ten days postoperatively, the patient developed systemic hives, difficulty breathing, and oral swelling. At 8 weeks postoperatively, the hardware was removed because of a suspected metal hypersensitivity. Despite experiencing perioral edema and difficulty breathing after the hardware removal, she had complete resolution of the symptoms at the 2-week, 6-week, and 12-month follow-up appointments. CONCLUSION: Hypersensitivities to metal-based implants can develop and cause local and systemic reactions...
April 2017: JBJS Case Connector
https://www.readbyqxmd.com/read/29204240/a-rare-case-of-diffuse-neurofibroma-masquerading-as-a-hemangioma-a-radiological-perspective
#6
Shaista Siddiqui, Zafar Ahmad Khan, Shagufta Wahab, Kafil Akhtar, Farhat Huma Ansari, Nani Lampung
Diffuse neurofibroma is a rarely encountered subtype of neurofibroma but the most common to be misdiagnosed. Its imaging appearance is very similar to that of a vascular malformation, and it is often labelled one until a biopsy proves it to be otherwise. The infrequency of its association with neurofibromatosis makes it a rare and difficult diagnosis. Here, we report the case of a 16-year-old girl who presented with the complaint of a gradually progressive swelling around the right ankle and heel, which was initially diagnosed as a case of a vascular malformation...
December 2017: Journal of Ultrasound
https://www.readbyqxmd.com/read/29197923/a-rare-case-of-an-acute-soleus-arcade-syndrome-complicated-by-a-ganglion-cyst-diagnosis-by-dynamic-ultrasound
#7
Leonhard Gruber, Alexander Loizides, Stephanie Klien, Thomas Trieb, Michael Koller, Wolfgang Löscher, Hannes Gruber
The soleus arcade syndrome is a rare compression neuropathy of the tibial nerve that often remains undiagnosed due to low clinical awareness and difficult diagnosis. We present the case of a female patient admitted with acute worsening of a pre-existing sensory tibial neuropathy and acute tibial nerve palsy after knee joint injection. After a knee magnetic resonance imaging remained non-diagnostic, dynamic ultrasonography was performed. Constriction by the soleus arcade and proximal swelling of the tibial nerve could be demonstrated during plantarflexion of the ankle by means of a dynamic examination in the standing patient...
November 29, 2017: Medical Ultrasonography
https://www.readbyqxmd.com/read/29195062/compressive-stockings-after-hindfoot-and-ankle-surgery
#8
Florian Grubhofer, Sabrina Catanzaro, Regula Schüpbach, Mohamed A Imam, Stephan Wirth
BACKGROUND: Swelling and pain are common after foot and ankle procedures. We hypothesized that compressive stockings (CS) treatment after hindfoot surgery would positively influence patient outcomes. METHODS: We undertook this randomized controlled trial in 87 consecutive patients to analyze the clinical effect of CS after hindfoot and ankle surgery and evaluate CS-wearing compliance using sensors that were implanted into CS. Ankle swelling, pain status, quality of life (SF-36 score), and the American Orthopaedic Foot & Ankle Score (AOFAS) were set as the primary end points...
November 1, 2017: Foot & Ankle International
https://www.readbyqxmd.com/read/29164814/a-thrombin-receptor-derived-imaging-agent-detects-subclinical-arthritis-in-mice
#9
Beth Friedman, Michael A Whitney, Elamprakash N Savariar, Christa Caneda, Paul Steinbach, Qing Xiong, Dina V Hingorani, Jessica Crisp, Stephen R Adams, Michael Kenner, Csilla N Lippert, Quyen T Nguyen, Monica Guma, Roger Y Tsien, Maripat Corr
OBJECTIVE: Functional imaging of synovitis could improve both early detection of rheumatoid arthritis (RA) and long-term outcomes. Motivated by the intersection of inflammation with coagulation protease activation, we examine coagulation protease activities in arthritic mice with a dual fluorescent Ratiometric thrombin-Activatable Cell Penetrating Peptide (RACPPNleTPRSFL ). METHOD: Mice with chronic transgenic K/BxN arthritis, or with arthritis on Day 1 of passive serum transfer induced arthritis (STIA), were imaged in vivo for Cy5 em: Cy7 em ratiometric fluorescence from proteolytic cleavage and activation of RACPPNleTPRSFL ...
November 22, 2017: Arthritis & Rheumatology
https://www.readbyqxmd.com/read/29145862/l161982-alleviates-collagen-induced-arthritis-in-mice-by-increasing-treg-cells-and-down-regulating-interleukin-17-and-monocyte-chemoattractant-protein-1-levels
#10
Liang Chen, Xianglei Wu, Jun Zhong, Dongqing Li
BACKGROUND: To investigate the effects and potential mechanism of L161982 (a kind of EP4 antagonist) on the collagen-induced arthritis (CIA) mice model. METHODS: The CIA mice model were first established by immunizing with Chicken Type II Collagen on DBA/1 mice. The CIA groups were administered once a day for 2 weeks with either 5 mg/kg L161982 by intraperitoneal injections (IP), 200 U celecoxib by intragastrical injections, or 100 μl PBS (IP). At the end of the study, total arthritis score and histopathologic examination were assessed to determine CIA severity...
November 16, 2017: BMC Musculoskeletal Disorders
https://www.readbyqxmd.com/read/29142816/unilateral-pulmonary-edema-in-a-patient-with-worsening-tricuspid-valve-regurgitation-a-secret-inside-pulmonary-veins
#11
Elvira Resciniti, Ilaria Caso, Iside Scarfò, Giuseppe Di Pasquale, Giovanni La Canna
We present the case of a 69-year-old patient who was referred to the Department of Echocardiography for surgical treatment of severe tricuspid valve regurgitation (TVR) with advanced congestive heart failure. In 2013 the patient underwent unsuccessful percutaneous ablation for permanent atrial fibrillation. In 2015, following numerous episodes of atrial fibrillation and congestive heart failure with left pleural effusion, the patient was admitted to another center. A transthoracic echocardiogram showed severe TVR and moderate precapillary pulmonary hypertension, confirmed at right cardiac catheterization...
October 2017: Journal of Cardiovascular Echography
https://www.readbyqxmd.com/read/29138302/disruption-of-the-opal-stop-codon-attenuates-chikungunya-virus-induced-arthritis-and-pathology
#12
Jennifer E Jones, Kristin M Long, Alan C Whitmore, Wes Sanders, Lance R Thurlow, Julia A Brown, Clayton R Morrison, Heather Vincent, Kayla M Peck, Christian Browning, Nathaniel Moorman, Jean K Lim, Mark T Heise
Chikungunya virus (CHIKV) is a mosquito-borne alphavirus responsible for several significant outbreaks of debilitating acute and chronic arthritis and arthralgia over the past decade. These include a recent outbreak in the Caribbean islands and the Americas that caused more than 1 million cases of viral arthralgia. Despite the major impact of CHIKV on global health, viral determinants that promote CHIKV-induced disease are incompletely understood. Most CHIKV strains contain a conserved opal stop codon at the end of the viral nsP3 gene...
November 14, 2017: MBio
https://www.readbyqxmd.com/read/29129457/acute-effects-of-graduated-elastic-compression-stockings-in-patients-with-symptomatic-varicose-veins-a-randomised-double-blind-placebo-controlled-trial
#13
Stavros K Kakkos, Marios Timpilis, Panayiotis Patrinos, Konstantinos M Nikolakopoulos, Chrysanthi P Papageorgopoulou, Anastasia K Kouri, Ioannis Ntouvas, Spyros I Papadoulas, George C Lampropoulos, Ioannis A Tsolakis
OBJECTIVES: To investigate the effectiveness of graduated elastic compression stockings (GECS) below the knee in improving symptoms in patients with varicose veins in the absence of high quality evidence. METHODS: This was a randomised double blind placebo controlled trial. Thirty patients with no experience of elastic stockings, presenting with primary varicose veins causing calf pain or aching were randomised to a GECS (18-21 mmHg at the ankle level, n=15) or a placebo stocking (0 mmHg, n=15)...
November 10, 2017: European Journal of Vascular and Endovascular Surgery
https://www.readbyqxmd.com/read/29105657/gait-training-after-spinal-cord-injury-safety-feasibility-and-gait-function-following-8-weeks-of-training-with-the-exoskeletons-from-ekso-bionics
#14
Carsten Bach Baunsgaard, Ulla Vig Nissen, Anne Katrin Brust, Angela Frotzler, Cornelia Ribeill, Yorck-Bernhard Kalke, Natacha León, Belén Gómez, Kersti Samuelsson, Wolfram Antepohl, Ulrika Holmström, Niklas Marklund, Thomas Glott, Arve Opheim, Jesus Benito, Narda Murillo, Janneke Nachtegaal, Willemijn Faber, Fin Biering-Sørensen
STUDY DESIGN: Prospective quasi-experimental study, pre- and post-design. OBJECTIVES: Assess safety, feasibility, training characteristics and changes in gait function for persons with spinal cord injury (SCI) using the robotic exoskeletons from Ekso Bionics. SETTING: Nine European rehabilitation centres. METHODS: Robotic exoskeleton gait training, three times weekly over 8 weeks. Time upright, time walking and steps in the device (training characteristics) were recorded longitudinally...
November 6, 2017: Spinal Cord
https://www.readbyqxmd.com/read/29096125/biaxial-mechanical-behavior-of-bovine-saphenous-venous-valve-leaflets
#15
Jiaqi Lu, Hsiao-Ying Shadow Huang
Chronic venous disease is caused by chronic venous insufficiency (CVI), which results in significant symptoms such as venous ulcers, ankle eczema, leg swelling, etc. Venous valve incompetence is a major cause of CVI. When the valves of veins in the leg become incompetent (i.e., do not close properly), blood is able to flow backwards (i.e., reflux), which results in blood pooling in the lower extremities, distal venous hypertension, and CVI. Current clinical therapies, such as surgical venous valve reconstruction and bioprosthetic venous valve replacement, are highly invasive and only moderately successful...
October 24, 2017: Journal of the Mechanical Behavior of Biomedical Materials
https://www.readbyqxmd.com/read/29083363/a-pseudotumoral-lesion-diagnosed-for-a-hypertrofic-fibrosis-at-the-proximal-stump-in-anterior-tibialis-tendon-missed-rupture-a-case-report
#16
Elena M Samaila, Filippo Luiso, Giacomo Trivellin, Matteo Brunelli, Bruno Magnan
The Anterior Tibialis is the most important muscle in ankle dorsiflexion. The anterior tibialis tendon (ATT)'s rupture is an infrequent condition which can be both traumatic and spontaneous. Clinic is poor and it is necessary to confirm the suspect by US or MRI. The reported case refers to a 40 years old man who had a direct trauma at ankle and midfoot which was originally conservatively treated for an ankle sprain. Three months later he returned with pain, swelling and paresthesia. MRI was performed showing a neoformation in the contest of ATT's rupture...
October 18, 2017: Acta Bio-medica: Atenei Parmensis
https://www.readbyqxmd.com/read/29079237/surgical-treatment-of-confirmed-intraosseous-lipoma-of-the-calcaneus-a-case-series
#17
Osman Emre Aycan, Abdi Keskin, Sami Sökücü, Devrim Özer, Fevziye Kabukçuoğlu, Yavuz Selim Kabukçuoğlu
Intraosseous lipoma of the calcaneus is a benign lesion formed by mature adipose tissue. When the lesion is symptomatic, the most frequent presentation is localized pain and soft tissue swelling. Because these lesions can regress spontaneously, conservative treatment methods are recommended. Operative excision is mostly required for painful lesions and pathologic fractures. The data from 14 patients with calcaneal intraosseous lipoma, who had undergone surgery in our clinic, were evaluated retrospectively. Using Milgram's classification system, 9 lesions were classified as stage 1, 4 as stage 2, and 1 as stage 3...
November 2017: Journal of Foot and Ankle Surgery: Official Publication of the American College of Foot and Ankle Surgeons
https://www.readbyqxmd.com/read/29071964/-effect-of-moxibustion-on-serum-il-17-and-tnf-%C3%AE-levels-in-collagen-induced-arthritis-rats
#18
Yuan Yin, Tian-Wei Chen, Rui Zhang, Wen-Zhu Ma
OBJECTIVE: To observe the influence of moxibustion on serum interleukin -17 (IL-17) and tumor necrosis factor alpha (TNF-α) levels in collagen-induced arthritis (CIA) rats, so as to study its mechanism underlying improvement of rheumatoid arthritis. METHODS: A total of 40 male Wistar rats were used in the present study, and 8 rats were randomly selected as a normal control group. The other 32 rats were modeled. The primary immunity emulsion was made with mixed Type Ⅱ chicken collagen and complete Freund's adjuvant, and 0...
April 25, 2017: Zhen Ci Yan Jiu, Acupuncture Research
https://www.readbyqxmd.com/read/29063748/new-data-on-chronic-venous-disease-a-new-place-for-cyclo-3%C3%A2-fort
#19
Stravos K Kakkos, Eliete Bouskela, Arkadiusz Jawien, Andrew N Nicolaides
With our increasing knowledge of the epidemiology, pathophysiology, investigation and clinical aspects of chronic venous disease (CVD) and new data on the various therapies available, an update of the recommendations on CVD and its management appears to be necessary. The symposium "New Data on Chronic Venous Disease, New Place for Cyclo 3® Fort", held at the annual meeting of the European Venous Forum (EVF) on June 30th, 2017 in Porto, Portugal, reported the recent developments on Ruscus+HMC+Vit C (Cyclo 3® Fort), including the results of a series of in vivo pharmacological experiments and a recent meta-analysis...
October 23, 2017: International Angiology: a Journal of the International Union of Angiology
https://www.readbyqxmd.com/read/29061135/prognostic-factors-for-recovery-following-acute-lateral-ankle-ligament-sprain-a-systematic-review
#20
Jacqueline Yewande Thompson, Christopher Byrne, Mark A Williams, David J Keene, Micheal Maia Schlussel, Sarah E Lamb
BACKGROUND: One-third of individuals who sustain an acute lateral ankle ligament sprain suffer significant disability due to pain, functional instability, mechanical instability or recurrent sprain after recovery plateaus at 1 to 5 years post injury. The identification of early prognostic factors associated with poor recovery may provide an opportunity for early-targeted intervention and improve outcome. METHODS: We performed a comprehensive search of AMED, EMBASE, Psych Info, CINAHL, SportDiscus, PubMed, CENTRAL, PEDro, OpenGrey, abstracts and conference proceedings from inception to September 2016...
October 23, 2017: BMC Musculoskeletal Disorders
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