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Ankle swelling

Malek Ghnaimat, Mohannad Alodat, Mohammad Aljazazi, Raad Al-Zaben, Jamal Alshwabkah
The giant cell tumor of the tendon sheath (GCTTS) is a benign lesion which arises from the synovium of a joint, bursa or tendon sheath, with 85% of the tumors occurring in the fingers and 12% of the tumors located in large joints such as the knee and ankle. The GCTTS is usually monoarticular, slowly proliferative and rarely locally aggressive. This paper reports three cases of this rare lesion in the knee. Patients presented with painful swelling in the anterior knee, MRI showed localized soft tissue masses which were able to be excised...
August 2016: Electronic Physician
Sergio Gianesini, Mirko Tessari, Primo Bacciglieri, Anna Maria Malagoni, Erica Menegatti, Savino Occhionorelli, Nino Basaglia, Paolo Zamboni
OBJECTIVE: Despite the fact that muscle pump activation is known to positively impact chronic lower limb edema, objective measurements of standardized exercises for venous-lymphatic rehab are lacking. The aim of this investigation is to determine the effectiveness of an addressed physical activity exploiting the advantages of an aquatic environment. MATERIAL AND METHODS: Thirty-two lower limbs of 16 patients affected by bilateral chronic leg swelling were included (12 females, 4 males)...
October 18, 2016: Phlebology
Rupesh Kumar, Anjana, Meghraj Kundan
INTRODUCTION: Osteochondroma is the most common benign tumour of the bone and is considered as developmental lesion of the bone. Common site of osteochondroma presentation is around the knee but calcaneal osteochondroma as such is a rare entity. Osteochondromas grow during childhood through adolescence, but usually the growth of osteochondroma ends when the epiphyseal plates close. In an adult, growth of an osteochondroma suggests the diagnosis of a malignant transformation. However, it can also present as pressure symptom in later phase of life...
April 2016: Journal of Orthopaedic Case Reports
Abhinav Goyal, Moiz Salahuddin, Yogesh Govil
A 31-year-old female with a history of lupus nephritis on Hydroxychloroquine, Prednisone, and Mycophenolate Mofetil (MMF) for 10 years presented to the hospital for ankle swelling. On day four, she started to have severe, nonbloody, watery diarrhea with abdominal distension and tenderness. Stool PCR was negative for C. difficile. CT abdomen/pelvis showed gaseous distension of the colon without any obstruction. Flexible sigmoidoscopy revealed a normal looking mucosa. Histopathology showed crypt atrophy and increased crypt apoptosis, consistent with MMF colitis...
2016: Case Reports in Gastrointestinal Medicine
Jan Paul Briet, Roderick M Houwert, Michiel G J S Hageman, Falco Hietbrink, David C Ring, Egbert Jan J M Verleisdonk
BACKGROUND: Swelling, tenderness, and ecchymosis don't correlate with time to functional recovery in patients with a lateral ankle sprain. It is established that psychosocial factors such as symptoms of depression and low pain self-efficacy correlate with pain intensity and magnitude of limitations in patients with musculoskeletal disorders. OBJECTIVE: We studied the correlation between pain self-efficacy or symptoms of depression and (1) ankle specific limitations and (2) pain intensity in patients with a lateral ankle sprain...
September 9, 2016: Injury
Werner Blättler, Hans-Jürgen Thomae, Felix Amsler
OBJECTIVE: The core symptoms of venous disease include leg discomfort or pain accompanied by sensations of heavy, weighty, or swollen legs. This suggests the presence of a cause and effect relationship between swelling and pain, resulting in the assumption that a venous disorder is responsible. The aim of this study was to investigate the relationship between leg volume increase and symptoms provoked by a period of stationary standing and also to investigate the effect of medical compression stockings (MCS)...
October 2016: Journal of Vascular Surgery. Venous and Lymphatic Disorders
Xiaoli Han, Dan Su, Xiaoyan Xian, Mingyang Zhou, Xianzhe Li, Jian Huang, Jinhui Wang, Huiyuan Gao
ETHNOPHARMACOLOGICAL RELEVANCE: Saussurea involucrate (Kar. et Kir.) Sch. -Bip is an endangered species of the Compositae family, and this species has long been used for the treatment of rheumatoid arthritis, dysmenorrhea, stomachache, and altitude sickness in Uighur folk and Chinese medicine. AIM OF THE STUDY: This study aimed to investigate the different therapeutic efficacy of alcohol infusion (SEI) and water decoction (SWD) of S. involucrata in treating rheumatoid arthritis using complete Freund's adjuvant (CFA)-induced arthritis (AA) in a rat model...
September 8, 2016: Journal of Ethnopharmacology
Seyed Alireza Mirghasemi, Elly Trepman, Mohammad Saleh Sadeghi, Narges Rahimi, Shervin Rashidinia
: Bone marrow edema syndrome (BMES) is an uncommon and self-limited syndrome characterized by extremity pain of unknown etiology. Symptoms may include sudden or gradual onset of swelling and pain at rest or during activity, usually at night. This syndrome mostly affects middle-aged men and younger women who have pain in the lower extremities. The most common sites involved with BMES, in decreasing order of frequency, are the bones about the hip, knee, ankle, and foot. The diagnosis of BMES is confirmed with magnetic resonance imaging to exclude other causes of bone marrow edema...
September 1, 2016: Foot & Ankle International
Qiao Han, Wang Bing, Yin Di, Li Hua, Li Shi-He, Zheng Yu-Hua, Han Xiu-Guo, Wang Yu-Gang, Fan Qi-Ming, Yang Shih-Mo, Tang Ting-Ting
Gouty arthritis is a rheumatic disease that is characterized by the deposition of monosodium urate (MSU) in synovial joints cause by the increased serum hyperuricemia. This study used a three-dimensional (3D) flowing microfluidic chip to screen the effective candidate against MSU-stimulated human umbilical vein endothelial cell (HUVEC) damage, and found kinsenoside (Kin) to be the leading active component of Anoectochilus roxburghi, one of the Chinese medicinal plant widely used in the treatment of gouty arthritis clinically...
2016: Cell Death & Disease
Fernando Diaz Dilernia, Ezequiel E Zaidenberg, Sebastian Gamsie, Danilo E R Taype Zamboni, Guido S Carabelli, Jorge D Barla, Carlos F Sancineto
Gluteal compartment syndrome (GCS) is extremely rare when compared to compartment syndrome in other anatomical regions, such as the forearm or the lower leg. It usually occurs in drug users following prolonged immobilization due to loss of consciousness. Another possible cause is trauma, which is rare and has only few reports in the literature. Physical examination may show tense and swollen buttocks and severe pain caused by passive range of motion. We present the case of a 70-year-old man who developed GCS after prolonged anterior-posterior pelvis compression...
2016: Case Reports in Orthopedics
Zhe-Qing Dong, Ji Zhu, De-Zhao Lu, Qin Chen, Ying-Ling Xu
BACKGROUND: Rheumatoid arthritis (RA) is a chronic systemic autoimmune disease. Previous study suggested that toll-like receptor (TLR) signaling pathway contributes to the development and progression of RA. In recent years, acupuncture has become one of the most vital treatments of arthralgia. But little is known about the mechanisms of improving RA by acupuncture. STUDY QUESTION: The study studied the effect of electroacupuncture in "Zusanli" and "Kunlun" acupoints on the expression of TLR4, myeloid differentiation factor 88 (MYD88), and NF-κB in adjuvant arthritis rats to clarify the molecular mechanism of acupuncture of RA...
August 29, 2016: American Journal of Therapeutics
Ayako Hirata, Takehisa Ogura, Norihide Hayashi, Sayaka Takenaka, Hideki Ito, Kennosuke Mizushina, Yuki Fujisawa, Naoko Yamashita, Sumie Nakahashi, Munetsugu Imamura, Rie Kujime, Hideto Kameda
OBJECTIVE: Ultrasonography has been prevalently used as a valid and objective modality for joint examination in patients with rheumatoid arthritis (RA). This study aimed to examine and compare the concordance between ultrasound, clinical, and patient-reported assessment of joint synovitis in RA. METHODS: Fifty patients with RA (84% female; median age, 69 years; disease duration, 2.6 years; disease activity score of 28 joints, 3.8) completed the self-evaluation of joint symptoms including pain and considerable stiffness in the (proximal) interphalangeal, metacarpophalangeal, wrist, elbow, shoulder, knee, and ankle joints...
August 26, 2016: Arthritis Care & Research
Yukihiro Toyota, Maasa Tamura, Yohei Kirino, Yumiko Sugiyama, Naomi Tsuchida, Yosuke Kunishita, Daiga Kishimoto, Reikou Kamiyama, Yasushi Miura, Kaoru Minegishi, Ryusuke Yoshimi, Atsuhisa Ueda, Hideaki Nakajima
OBJECTIVES: To clarify the use of musculoskeletal ultrasonography (US) of ankle joints in rheumatoid arthritis (RA). METHODS: Consecutive RA patients with or without ankle symptoms participated in the study. The US, clinical examination (CE), and patients' visual analog scale for pain (pVAS) for ankles were assessed. Prevalence of tibiotalar joint synovitis and tenosynovitis were assessed by grayscale (GS) and power Doppler (PD) US using a semi-quantitative grading (0-3)...
September 1, 2016: Modern Rheumatology
Shishir Suranigi, Kanagasabai Rengasamy, Syed Najimudeen, James Gnanadoss
Osteochondroma or exostosis is the most common benign bone tumor, and occurring frequently in the proximal humerus, tibia, and distal femur. It rarely affects talus. Osteochondroma of talus is a very rare etiology of tarsal tunnel syndrome (TTS). We report a rare case of extensive osteochondroma of the talus in a 60 year old female presenting with multiple swellings around the ankle and symptoms suggestive of tarsal tunnel syndrome. En-block excision of the multiple masses was done. Histopathological examination confirmed the diagnosis of osteochondroma...
June 2016: Archives of Bone and Joint Surgery
Nihal Ozaras, Nuri Havan, Emine Poyraz, Aylin Rezvanı, Teoman Aydın
[Purpose] Spondyloarthritis is a major inflammatory disease followed-up in the rheumatology clinics, foot involvement in spodyloarthritis is common. The functional states of patients with spondyloarthritis are usually evaluated globally. The aim of this study was to assess the foot involvement-related functional limitations in patients with spondyloarthritis. [Subjects and Methods] Patients with ankylosing spondylitis and psoriatic arthritis with foot pain more than 4 weeks who underwent anteroposterior and lateral feet radiography were enrolled into the study...
July 2016: Journal of Physical Therapy Science
Qiaoling Chen, Shuangying Huang, Xiaoli Chen, Lei Feng, Xuxia Zhu
OBJECTIVE: To discuss the clinical effect on swelling and pain after total knee arthroplasty treated with acupoint massage, mild moxibustion and routine detumescence. METHODS: One hundred and twenty patients of knee osteoarthritis (KOA) after total knee arthroplasty (TKA), were randomized into an observation group and a control group, 60 cases in each one. In the control group, after TKA, the routine detumescence was applied, including elastic bandage compression, the operated limb raising exercise, knee joint braking, local ice compress, intermittent pneumatic compression, active ankle pumping and quadriceps contraction exercise, continuous passive mechanical exercise, using stretch socks, oral administration of rivaroxaban tablets, 10 mg, once a day, continuously for 21 to 24 days...
May 2016: Zhongguo Zhen Jiu, Chinese Acupuncture & Moxibustion
Lin Zou, Guichun Zhang, Lifeng Liu, Chen Chen, Xuecheng Cao, Jinfang Cai
To investigate the expression of hypoxia inducible factor (HIF-1α) and vascular endothelial growth factor (VEGF) in the synovium of collagen-induced arthritis (CIA) joint, and whether the PI3K pathway regulates angiogenesis in rheumatoid arthritis or not. A randomized controlled according to the principle of the rats were divided into normal control group (10 rats) and the experimental group (40 rats). The experimental group rats were established as type II collagen plus adjuvant Freund's complete adjuvant-induced arthritis model...
2016: American Journal of Translational Research
Cheng-Yu Chen, Chen-Ming Su, Chin-Jung Hsu, Chien-Chung Huang, Shih-Wei Wang, Shih-Chia Liu, Wei-Cheng Chen, Lih-Jyh Fuh, Chih-Hsin Tang
Angiogenesis is the formation of new capillaries from pre-existing vasculature. The perpetuation of angiogenesis plays a critical role in the pathogenesis of various disease states including rheumatoid arthritis (RA). Cysteine-rich 61 (Cyr61 or CCN1) is an important proinflammatory cytokine in RA. Here, we investigated the role of CCN1 in angiogenesis associated with vascular endothelial growth factor (VEGF) production and osteoblasts. We found higher expression of CCN1 and VEGF in synovial fluid from RA patients compared with healthy controls...
July 28, 2016: Journal of Bone and Mineral Research: the Official Journal of the American Society for Bone and Mineral Research
Se Hee Kim, Sang Sik Choi, Mi Kyung Lee, Jung Eun Kin
Most cases of complex regional pain syndrome (CRPS) occur after some inciting injury. There are a few cases of CRPS after an operation for disc disease. CRPS from a mild herniated intervertebral disc (HIVD) without surgical intervention is even rarer than CRPS after an operation for disc disease.A 22-year-old man was transferred to a pain clinic. He had continuously complained about back and right leg pain. He presented with a skin color change in the right lower leg, intermittent resting tremor, stiffness, and swelling in the right leg...
July 2016: Pain Physician
Rita Katznelson, Shira C Segal, Hance Clarke
Hyperbaric oxygen therapy (HBOT) is a treatment that delivers 100% oxygen at increased atmospheric pressures. The efficacy of HBOT for treating pain has been described in various animal pain models and may have clinical efficacy in the treatment of human chronic pain syndromes. We present our experience with posttraumatic Complex Regional Pain Syndrome (CRPS) type 2 in a patient who underwent 15 sessions of HBOT. A 41-year-old male with one-year history of CRPS of left foot followed by left ankle fracture demonstrated less pain, decreased swelling, less allodynia, and improvement in skin color and range of motion of the lower limb after 3 weeks of HBOT...
2016: Pain Research & Management: the Journal of the Canadian Pain Society
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