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https://www.readbyqxmd.com/read/27913509/the-post-thrombotic-syndrome
#1
Susan R Kahn
The post-thrombotic syndrome (PTS) is a frequent, sometimes disabling complication of deep vein thrombosis (DVT) that reduces quality of life and is costly. This article discusses risk factors for PTS after DVT and available means to prevent and treat PTS, with a focus on new information in the field. After DVT, PTS will develop in 20% to 50% of patients, and severe PTS, including venous ulcers, will develop in 5% to 10%. The principal risk factors for PTS are anatomically extensive DVT, recurrent ipsilateral DVT, persistent leg symptoms 1 month after acute DVT, obesity, and older age...
December 2, 2016: Hematology—the Education Program of the American Society of Hematology
https://www.readbyqxmd.com/read/27904827/presentation-of-idiopathic-retroperitoneal-fibrosis-at-a-young-age-a-rare-case-report
#2
Priyanka Minocha, Ankur Setia
Abdominal pain is a very common symptom in all age groups but retroperitoneal fibrosis is a rare differential diagnosis suspected in young patients presenting with nonspecific abdominal pain and symptoms of obstructive uropathy. Presented here is a case of a 16-year-old boy who presented with symptoms of persistent abdominal pain and a previous history of swelling in the left leg. A computed tomography (CT) scan suggested retroperitoneal fibrosis and an exploratory laparotomy and histopathological examination were performed for definitive diagnosis...
November 2016: Intractable & Rare Diseases Research
https://www.readbyqxmd.com/read/27900974/disseminated-mycobacteria-chelonae-infection-in-a-kidney-pancreas-transplant-recipient-a-case-report-and-review-of-the-literature
#3
Shafi Malik, Ananda Ghosh, Shahid Husain
A 40-year-old male with a long-standing history of type 1 diabetes with end-stage renal failure underwent combined kidney-pancreas (KP) transplant from a standard criteria donor. Post-operative course was uncomplicated with good primary function of both transplant grafts. Induction was with thymoglobulin and maintenance immunosuppression was with tacrolimus, mycophenolate mofetil and prednisolone. Nine weeks post-transplant, the patient developed dysfunction of both grafts. Panel reactive antibody testing revealed that the patient had developed a de novo donor-specific antibody and considering an antibody-mediated rejection the patient was treated with intravenous pulse methyl prednisone 500 mg ×3 doses, IV immunoglobulin 2 mg/kg in two divided doses, and ATG 7 mg/kg (total dose of 700 mg)...
November 2016: Saudi Journal of Kidney Diseases and Transplantation
https://www.readbyqxmd.com/read/27885342/venous-adventitial-cystic-disease-a-review-of-45-cases-treated-since-1963
#4
REVIEW
Corey Bascone, Mazen Iqbal, Patrick Narh-Martey, Mauricio Szuchmacher, Michael Cicchillo, Kambhampaty V Krishnasastry
Purpose. To review and identify the most accurate ways of diagnosing and treating adventitial cystic disease (ACD) of the venous system. Methods. Cases of ACD were collected through three popular medical databases, including PubMed, Cochrane, OVID, and MEDLINE. After reviewing the literature, the sites of occurrence of 323 cases of adventitial cystic disease were documented, and all cases of arterial ACD were excluded. The clinical features, treatment, and subsequent course of 45 cases of venous ACD are included in this paper...
2016: International Journal of Vascular Medicine
https://www.readbyqxmd.com/read/27885298/klippel-trenaunay-syndrome-a-case-report
#5
R K Sah, S Sharma, S Ghimire, B B Bagale, M Kayastha, R H Chapagain
Klippel-Trenaunaysyndrome(KTS) is a rare congenital condition usually presenting with port wine stains, excessive growth of bones and soft tissue and varicose veins which most commonly occurs in the legs, but it also may affect the arms, face, head, or internal organs. We report a case of term male neonate with clinical findings of Port-wine stain, multiple cystic swellings with ultrasonographic findings suggestive of vascular malformations and limb abnormalities in the form ofsoft tissue hypertrophy of right upper limb, polydactyly of right hand and syndactyly of left hand consistent withKlippel-Trenaunay syndrome...
May 2016: Journal of Nepal Health Research Council
https://www.readbyqxmd.com/read/27881584/tuberculosis-presenting-as-a-swollen-calf
#6
Deevia Kotecha, Mini Sardar, Mark David Latimer
We report the case of an 83-year-old man who presented with swelling of his left lower leg. Subsequent investigations revealed that the swelling was due to a Mycobacterium tuberculosis abscess in the tibialis anterior muscle.
November 23, 2016: BMJ Case Reports
https://www.readbyqxmd.com/read/27853081/unusual-initial-manifestation-of-acquired-hemophilia-a-a-normal-activated-partial-thromboplastin-time-intramuscular-hematoma-and-cerebral-hemorrhage
#7
Nobuaki Tsuyama, Toshihisa Ichiba, Hiroshi Naito
We herein present a case of acquired hemophilia A with a normal activated partial thromboplastin (aPTT), intramuscular hematoma and cerebral hemorrhage occurring in a 73-year-old man. The patient visited our emergency department with gait disturbance, pain and swelling in his right leg. Computed tomography (CT) and magnetic resonance imaging (MRI) revealed intramuscular hematoma and intracranial hemorrhage. The results of initial coagulation studies were normal, but repeated coagulation studies revealed an isolated prolongation of the aPTT...
2016: Internal Medicine
https://www.readbyqxmd.com/read/27830895/thrombolysis-for-acute-deep-vein-thrombosis
#8
REVIEW
Lorna Watson, Cathryn Broderick, Matthew P Armon
BACKGROUND: Standard treatment for deep vein thrombosis aims to reduce immediate complications. Use of thrombolysis or clot dissolving drugs could reduce the long-term complications of post-thrombotic syndrome (PTS) including pain, swelling, skin discolouration, or venous ulceration in the affected leg. This is the third update of a review first published in 2004. OBJECTIVES: To assess the effects of thrombolytic therapy and anticoagulation compared to anticoagulation alone for the management of people with acute deep vein thrombosis (DVT) of the lower limb as determined by the effects on pulmonary embolism, recurrent venous thromboembolism, major bleeding, post-thrombotic complications, venous patency and venous function...
November 10, 2016: Cochrane Database of Systematic Reviews
https://www.readbyqxmd.com/read/27810694/a-medieval-description-of-metastatic-breast-cancer-from-avicenna-s-view-point
#9
Mohammad M Zarshenas, Afshin Mohammadi-Bardbori
Historically, one of the earliest breast cancer case descriptions comes from an Egyptian manuscript so called "the Edwin Smith Papyrus" dating back to the Pyramid Age. However, apart from all respective documents remained from the antiquity, concepts and standpoints of Avicenna (Ibn Sina; a famous Persian physician) in regard of the cancer are interesting. A case of breast cancer and metastatic condition has been reported by Avicenna in the Canon of Medicine. This report can be considered as a very early report of metastatic or stage IV breast cancer...
October 27, 2016: Breast: Official Journal of the European Society of Mastology
https://www.readbyqxmd.com/read/27801353/endovascular-treatment-of-iliofemoral-deep-vein-thrombosis-in-pregnancy-using-us-guided-percutaneous-aspiration-thrombectomy
#10
Murat Gedikoglu, Levent Oguzkurt
PURPOSE: We aimed to describe ultrasonography (US)-guided percutaneous aspiration thrombectomy in pregnant women with iliofemoral deep vein thrombosis. METHODS: This study included nine pregnant women with acute and subacute iliofemoral deep vein thrombosis, who were severe symptomatic cases with massive swelling and pain of the leg. Patients were excluded from the study if they had only femoropopliteal deep vein thrombosis or mild symptoms of deep vein thrombosis...
November 1, 2016: Diagnostic and Interventional Radiology: Official Journal of the Turkish Society of Radiology
https://www.readbyqxmd.com/read/27793867/non-traumatic-trans-diaphragmatic-intercostal-hernia-and-cor-pulmonale-in-a-patient-with-poorly-controlled-obstructive-sleep-apnoea
#11
Syed Basharath Mehdi, Salem Madi, Jordan Sudworth
Trans-diaphragmatic intercostal hernia is a rare entity. Patient with multiple medical comorbidities, including obstructive sleep apnoea, presents with shortness of breath, leg oedema and a bulging swelling through the right chest wall. CT shows partial herniation of the right lung and liver through intercostal space and an echocardiogram reveals right heart failure. He was treated initially with continuous positive airway pressure with poor response and subsequently treated with adaptive servo ventilation with much better symptomatic relief and treatment tolerance...
October 28, 2016: BMJ Case Reports
https://www.readbyqxmd.com/read/27790498/massive-pulmonary-embolism-in-a-patient-using-warfarin-at-therapeutic-dose
#12
Sunnetcioglu Aysel, Esen Ramazan, Arisoy Ahmet
Warfarin sodium is commonly used for the prevention and treatment of thromboembolism. The efficacy of warfarin therapy depends on maintaining the International Normalised Ratio (INR) within the target range for the indication. A 56-year-old male presented to the emergency department with dyspnea and chest pain, together with pain and swelling in both legs. The patient had been taking warfarin at the therapeutic dose since having undergone an aortic valve replacement four years ago. His vital signs were an arterial pressure of 60/30 heart rate of 138 beats per minute, respiratory rate of 30 per minute and oxygen saturation of 60%...
September 2016: Journal of Clinical and Diagnostic Research: JCDR
https://www.readbyqxmd.com/read/27774697/livedoid-vasculopathy-and-popliteal-artery-occlusion-in-a-patient-with-protein-s-deficiency
#13
Takayuki Nakayama, Kentaro Mizutani, Ichiro Hanamura, Hidefumi Kato, Akiyoshi Takami, Kyosuke Takeshita, Daisuke Watanabe
Livedoid vasculopathy (LV) is a chronic disease with recurrent reticularis and ulcers, mainly affecting the feet and lower legs. The pathogenesis of LV has not been yet thoroughly understood, but thrombosis is thought to play a major role because fibrin deposition within both the wall and lumen of affected vessels is pathologically detected. A 68-year-old woman first presented to our hospital in 2004 with a 6-year history of a reticular rash and ulceration on the lower legs. Screening tests for vasculitis and collagen disease were mostly normal, leading to diagnosis of LV...
October 24, 2016: Journal of Dermatology
https://www.readbyqxmd.com/read/27768206/straight-configuration-saphenous-vein-transposition-to-popliteal-artery-for-vascular-access
#14
Gentian Caco, Dhurata Golemi, Eriola Likaj
INTRODUCTION: The saphenous vein is commonly used as a vascular graft in peripheral artery surgery but rarely used for vascular access. The literature on straight configuration saphenous vein transposition to the popliteal artery is scarce. Here we present two cases of straight configuration saphenous vein transposition to the popliteal artery for vascular access, the surgical technique and respective follow-up. CASE REPORT: Two young men, aged 29 and 36 years, were chosen for lower-limb vascular access for hemodialysis...
October 21, 2016: Journal of Vascular Access
https://www.readbyqxmd.com/read/27765546/intravascular-fibrolipoma-of-the-femoral-vein
#15
Chao Jiang, Leng Ni, Changwei Liu, Congwei Jia, Xining Wu, Jianyi Wang, Bao Liu
Lipoma of the lower leg vein is rare, and the histopathological variant, fibrolipoma, is even rarer. Here, we report an intravascular fibrolipoma located at the junction of the deep femoral vein and the femoral vein in a 50-year-old male patient. Tumor resection and venous reconstruction with a prosthetic graft were performed. Eight months later, the patient was asymptomatic and did not exhibit swelling. To our knowledge, this is the first case report of an intravascular fibrolipoma in the literature. Lower vein venography, computed tomography venography, ultrasonography, and histologic images are presented, along with a description of the procedures employed for tumor resection and venous reconstruction...
October 17, 2016: Annals of Vascular Surgery
https://www.readbyqxmd.com/read/27756859/a-specifically-designed-aquatic-exercise-protocol-to-reduce-chronic-lower-limb-edema
#16
Sergio Gianesini, Mirko Tessari, Primo Bacciglieri, Anna Maria Malagoni, Erica Menegatti, Savino Occhionorelli, Nino Basaglia, Paolo Zamboni
OBJECTIVE: Despite the fact that muscle pump activation is known to positively impact chronic lower limb edema, objective measurements of standardized exercises for venous-lymphatic rehab are lacking. The aim of this investigation is to determine the effectiveness of an addressed physical activity exploiting the advantages of an aquatic environment. MATERIAL AND METHODS: Thirty-two lower limbs of 16 patients affected by bilateral chronic leg swelling were included (12 females, 4 males)...
October 18, 2016: Phlebology
https://www.readbyqxmd.com/read/27756790/the-compartment-syndrome-is-the-intra-compartment-pressure-a-reliable-indicator-for-early-diagnosis
#17
Iftah Nudel, Luis Dorfmann, Gal deBotton
Compartment syndrome (CS) occurs when the pressure in an enclosed compartment increases due to tissue swelling or internal bleeding. As the intra-compartmental pressure (ICP) builds up, the blood flow to the tissue or the organ is compromised, resulting in ischemia, necrosis and damage to the nerves and other tissues. At the present there are no established diagnostic procedures, and clinical observations such as pain, paralysis and even compartment pressure monitoring are an unreliable determinant of the presence of the syndrome...
October 18, 2016: Mathematical Medicine and Biology: a Journal of the IMA
https://www.readbyqxmd.com/read/27699160/cystic-disease-of-the-groin-presenting-as-compression-of-a-femoral-vessel
#18
Hyung-Kee Kim, Deokbi Hwang, Sujin Park, Won-Ju Jeong, An Na Seo, Seung Huh
In this study, we describe our diagnosis and treatment of two patients who presented with femoral vessel compression caused by a cystic lesion in the groin. One case was diagnosed as adventitial cystic disease (ACD) of the common femoral artery resulting in leg claudication and the other was diagnosed as a ganglion cyst (GC) causing femoral vein compression and unilateral leg swelling. The operative findings differed between these two cases with respect to the dissection of the cyst and femoral vessel, but the postoperative histological examination results were similar...
September 2016: Vascular Specialist International
https://www.readbyqxmd.com/read/27689230/-prostate-carcinoma%C3%A2-swelling-of-the-leg%C3%A2-lymphedema-is-the-equation-correct
#19
C Harzendorf, A Schmidt, T Hirsch
Prostate carcinomas are often associated with lymphedemas of the leg following surgical treatment. Lymphedema is treated using complete decongestive therapy (CDT) with manual lymph drainage and compressive bandaging or stockings. Lymphedema resulting from a distinct iliac lymph node metastasis is a rare condition. A 73-year-old patient with a diagnosed prostate carcinoma presented with distinct swelling in the right leg. Iliac and leg vein thrombosis could not be ruled out. An ultrasound image revealed a large lesion surrounding the right iliac arteries...
September 29, 2016: Der Internist
https://www.readbyqxmd.com/read/27688220/effects-of-kinesio-taping-compared-to-arterio-venous-impulse-system%C3%A2-on-limb-swelling-and-skin-temperature-after-total-knee-arthroplasty
#20
Christoph Windisch, Steffen Brodt, Eric Röhner, Georg Matziolis
PURPOSE: It is an established fact that post-operative (p.o.) soft-tissue swelling and lymphoedema after total knee arthroplasty (TKA) have a major influence on the p.o. early functional outcome. Kinesio taping has a proven clinical effect in increasing lymph drainage. Despite the decades of experience gained and the assumed positive effects, hardly any investigations have been conducted to date on the influence of Kinesio taping on the p.o. healing process after TKA. The objective of the present study was to test the hypothesis that Kinesio taping used as a lymph application leads to a reduction of p...
September 29, 2016: International Orthopaedics
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