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idiopathic intermediate uveitis

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https://www.readbyqxmd.com/read/27886802/advancements-in-the-management-of-uveitis
#1
REVIEW
Sergio Schwartzman
Uveitis may exist as a clinical manifestation of an underlying systemic disease or may represent an idiopathic entity, sometimes with a very characteristic pattern. Different forms of uveitis have been defined on the basis of three important variables: chronicity, anatomic location, and underlying etiology. The evolving understanding of the immune system has resulted in a more targeted approach to manage patients with different forms of uveitis, although clearly this approach is at a very early stage. Altered patterns of cellular processing and different cytokine expression, including TNF, IL-1, IL-2, IL-6, and IL17, have been defined in uveitis, and this has laid the pathway for targeted therapy...
April 2016: Best Practice & Research. Clinical Rheumatology
https://www.readbyqxmd.com/read/27782772/clinical-patterns-and-causes-of-intraocular-inflammation-in-a-uveitis-patient-cohort-from-egypt
#2
Rowayda M Amin, Mohamed Gowieda, Ahmed Bedda, Ahmed Kamel, Alaa Radwan
PURPOSE: To analyze the patterns and causes of intraocular inflammation in patients attending uveitis referral clinics in Egypt. METHODS: The study included 454 patients with uveitis examined both at the Department of Ophthalmology, Alexandria Faculty of Medicine, and tertiary uveitis referral clinics in Cairo and the International Eye Clinic in Upper Egypt, between August 2013 and March 2016. All patients had a comprehensive ocular examination and systemic work-up...
October 26, 2016: Ocular Immunology and Inflammation
https://www.readbyqxmd.com/read/27782762/epidemiology-and-clinical-features-of-uveitis-from-urban-populations-in-south-india
#3
Swapnali Sabhapandit, Somasheila I Murthy, Vivek M Singh, Ketaki Gaitonde, Madhumita Gopal, Kerul Marsonia, Shajeera Sajid, Kalpana Babu
PURPOSE: To report the epidemiology of uveitis in two urban centers in South India. METHODS: Case records seen between January 2014 and December 2014 at two tertiary eye centers in South India were retrospectively reviewed. RESULTS: A total of 1123 patients in the study population had uveitis. Anterior uveitis was seen in 48.9%, posterior in 20.5%, intermediate in 17.3%, and panuveitis in 13.3%. Of these cases, 68.4% were acute uveitis. Pediatric uveitis constituted 6...
October 26, 2016: Ocular Immunology and Inflammation
https://www.readbyqxmd.com/read/27726522/the-spectrum-of-uveitis-in-southern-vietnam
#4
Myhanh Nguyen, Jay Siak, Soon-Phaik Chee, Vo Quang Hong Diem
PURPOSE: To describe the pattern of uveitis among Vietnamese at two eye hospitals in Southern Vietnam. METHODS: We retrospectively reviewed the charts of 212 consecutive uveitis cases that presented to two eye hospitals in Ho Chi Minh City, Vietnam, from July 2011 to February 2015. The patients were identified from a database maintained by the hospitals. Patients with keratitis, episcleritis, orbital inflammation, post-surgical endophthalmitis, traumatic iritis, and corneal graft rejection were excluded...
October 11, 2016: Ocular Immunology and Inflammation
https://www.readbyqxmd.com/read/27601874/a-10-year-review-of-pediatric-uveitis-at-a-hispanic-dominated-tertiary-pediatric-ophthalmic-clinic
#5
Kruti P Dajee, Jennifer Landau Rossen, Monica L Bratton, Jess T Whitson, Yu-Guang He
PURPOSE: The aim of this study was to evaluate the characteristics and outcomes of pediatric uveitis cases at a large tertiary referral center in Dallas, TX, USA. MATERIALS AND METHODS: The authors performed a retrospective chart review between 2001 and 2011 to identify children with uveitis. RESULTS: A total of 46 children (68 eyes) with uveitis were identified. Sixty-seven percent were Hispanic, and the mean age was 9.2 years. The majority of cases were idiopathic (74%)...
2016: Clinical Ophthalmology
https://www.readbyqxmd.com/read/27598822/phacoemulsification-with-intraocular-lens-implantation-in-pediatric-uveitis-a-retrospective-study
#6
Sudha K Ganesh, Saurabh Mistry
PURPOSE: To analyze the outcome of phacoemulsification with primary posterior chamber intraocular lens (IOL) implantation without primary posterior capsulorhexis in older children with uveitis. METHODS: Retrospective study of children with uveitis who underwent phacoemulsification with IOL implantation between January 2006 and May 2014. RESULTS: Twenty-one eyes of 16 children were included. Mean age at cataract surgery was 10.9 years. Juvenile idiopathic arthritis was associated in 37...
September 6, 2016: Ocular Immunology and Inflammation
https://www.readbyqxmd.com/read/27555706/demographic-and-clinical-features-of-pediatric-uveitis-at-a-tertiary-referral-center-in-iran
#7
Mansour Rahimi, Marjan Oustad, Afsaneh Ashrafi
PURPOSE: To determine the clinical features and distribution of uveitis in the pediatric age group at a referral eye care center in Shiraz, South Iran. MATERIALS AND METHODS: All new cases of uveitis in patients 18-year-old or younger referred from January 2007 to December 2013 were enrolled in this study. The patient underwent a complete history of systemic and ocular diseases, comprehensive ophthalmic examination. Patients were classified according to the International Uveitis Study Group definitions...
July 2016: Middle East African Journal of Ophthalmology
https://www.readbyqxmd.com/read/27467180/a-focus-on-the-epidemiology-of-uveitis
#8
Theodora Tsirouki, Anna Dastiridou, Chrysanthos Symeonidis, Ourania Tounakaki, Irini Brazitikou, Christos Kalogeropoulos, Sofia Androudi
PURPOSE: Uveitis is a common, sight-threatening inflammatory ocular disease and includes multiple heterogeneous clinical entities. The prevalence of various types of uveitis depends upon multiple factors, such as age, sex, race, geographic distribution, environmental influence, genetics, and social habits. Epidemiologic research of uveitis is necessary to understand the etiology and immunopathogenesis of this group of diseases. The present study attempts to concentrate on the most recent information on the epidemiology of uveitis and compare it with previous knowledge...
July 28, 2016: Ocular Immunology and Inflammation
https://www.readbyqxmd.com/read/27432171/adalimumab-for-the-treatment-of-refractory-noninfectious-paediatric-uveitis
#9
Alicia Muñoz-Gallego, Estefanía Barral, Eugenia Enríquez, Pilar Tejada, Ana Barceló, Jaime de Inocencio
To report the experience of our center with the use of adalimumab (ADA) for the treatment of severe refractory noninfectious paediatric uveitis. The study is a retrospective case series of all paediatric patients with refractory uveitis who were treated with ADA at the Paediatric Uveitis Unit of our center from 2008 to 2015. We present 12 patients (6 Juvenile idiopathic arthritis-associated uveitis, 4 idiopathic panuveitis, 1 early-onset sarcoidosis-associated panuveitis, and 1 intermediate uveitis), with uveitis in 19/24 eyes...
July 18, 2016: International Ophthalmology
https://www.readbyqxmd.com/read/27419535/the-pattern-of-uveitis-among-chinese-malays-and-indians-in-singapore
#10
Jay Siak, Anne Jansen, Samanthila Waduthantri, Chin-Sheng Teoh, Aliza Jap, Soon-Phaik Chee
PURPOSE: To describe the pattern of uveitis among Chinese, Malays, and Indians at a tertiary referral institution in Singapore. METHODS: Charts between January 1997 and December 2010 were retrospectively reviewed. Charts between January 2014 and December 2014 were prospectively reviewed. RESULTS: A total of 1249 and 148 charts were retrospectively and prospectively reviewed, respectively. The top causes of anterior uveitis (AU) were HLA-B27, idiopathic, and CMV AU...
July 15, 2016: Ocular Immunology and Inflammation
https://www.readbyqxmd.com/read/27335142/clinical-features-of-uveitis-in-children-and-adolescents-at-a-tertiary-referral-centre-in-tokyo
#11
Hiroshi Keino, Takayo Watanabe, Wakako Taki, Makiko Nakayama, Tomoko Nakamura, Kunimasa Yan, Annabelle A Okada
OBJECTIVES: To analyse clinical features, systemic associations, treatment and visual outcomes of uveitis in children and adolescents at a tertiary centre in Tokyo. METHODS: Clinical records of 64 patients under the age of 20 years who presented between 2001 and 2013 to the Ocular Inflammation Service of the Kyorin Eye Center, Tokyo were reviewed retrospectively. RESULTS: Of the 64 patients, there was a predominance of girls (70%) and bilateral disease (81%)...
June 22, 2016: British Journal of Ophthalmology
https://www.readbyqxmd.com/read/27070829/clinical-patterns-of-uveitis-in-a-tertiary-center-in-north-china
#12
Fei Gao, Chan Zhao, Gangwei Cheng, Minghang Pei, Xinshu Liu, Min Wang, Shanshan Jia, Meifen Zhang
PURPOSE: To analyze the spectrum of uveitis at a tertiary hospital in northern China. METHODS: This study is a retrospective study from June 2014 to February 2015. A total of 606 consecutive patients with uveitis were screened for etiologies and classified according to the anatomic sites of inflammation. RESULTS: The mean age at presentation was 33.8 ± 15.5 years old. Males and females were almost equally affected. Panuveitis was the most common anatomic diagnosis, followed by anterior, posterior, and intermediate uveitis...
April 12, 2016: Ocular Immunology and Inflammation
https://www.readbyqxmd.com/read/27051493/pars-planitis-epidemiology-clinical-characteristics-management-and-visual-prognosis
#13
REVIEW
Pinar Cakar Ozdal, Nilufer Berker, Ilknur Tugal-Tutkun
Pars planitis is an idiopathic chronic intermediate uveitis which predominantly affects children and adolescents, and accounts for 5-26.7% of pediatric uveitis. Although an autoimmune process with a genetic predisposition has been suggested, its etiology still remains unknown. The most common presenting symptoms are floaters and blurred vision. Diffuse vitreous cells, haze, snowballs and snowbanks are typical findings of pars planitis. Peripheral retinal vasculitis, optic disc edema and anterior segment inflammation are other well-known findings...
October 2015: Journal of Ophthalmic & Vision Research
https://www.readbyqxmd.com/read/26910754/patterns-of-uveitis-in-a-tertiary-care-referral-institute-in-saudi-arabia
#14
Hassan A Al Dhibi, Hanan N Al Shamsi, Ammar M Al-Mahmood, Hassan M Al Taweel, Mohammed A Al Shamrani, J Fernando Arevalo, Vishali Gupta, The Kkesh Uveitis Survey Study Group
PURPOSE: To present the pattern, causes and complications of uveitis in one of the tertiary eye centers in Saudi Arabia. METHODS: In this retrospective study, clinical records of randomly selected cases of uveitis attending the King Khaled Eye Specialist Hospital, Saudi Arabia, from 2001 to 2010, were reviewed. RESULTS: Our series included 888 out of 1286 cases of uveitis. Among them, there were 390 men (43.9%) with a mean age of 39.6 ± 11 (range: 6-94 years)...
February 24, 2016: Ocular Immunology and Inflammation
https://www.readbyqxmd.com/read/26408195/patterns-of-uveitis-at-the-apex-institute-for-eye-care-in-india-results-from-a-prospectively-enrolled-patient-data-base-2011-2013
#15
Pradeep Venkatesh, Varun Gogia, Bhavin Shah, Shikha Gupta, Pradeep Sagar, Satpal Garg
The purpose of the study was to identify the clinical and etiological profile of uveitis at the apex institute for eye care in India. This is a prospective, prevalence study. 980 consecutive patients with uveitis referred to uvea clinic, Dr. RP Centre for Ophthalmic Sciences (Ophthalmology division, All India Institute of Medical Sciences). Demographic data of each patient were noted and a thorough ocular examination including slit lamp examination and dilated fundus evaluation was carried out. OCT and fluorescein angiography were undertaken whenever indicated...
June 2016: International Ophthalmology
https://www.readbyqxmd.com/read/26349156/-complete-and-permanent-regression-of-persistent-uveitic-cystoid-macular-edema-after-single-intravitreal-iniection-of-aflibercept-in-patient-previously-treated-with-multiple-intravitreal-injections-of-ranibizumab-and-bevacizumab
#16
Marcin Swituła
A case report of a twenty-year-old man with quiescent, idiopathic intermediate uveitis in his right eye treated with systemic corticosteroids and persistent cystoid macular edema, admitted for further treatment due to chronic reduction in visual acuity, is presented. A therapy involving intravitreal injections of ranibizumab (Lucentis), followed by bevacizumab (Avastin) was started, leading to transient improvement of visual acuity and edema reduction confirmed in optical coherent tomography. A de cision of switching to intravitreal aflibercept (Eylea) was made...
2015: Klinika Oczna
https://www.readbyqxmd.com/read/26309888/results-of-intravitreal-dexamethasone-implant-0-7-mg-ozurdex%C3%A2-in-non-infectious-posterior-uveitis
#17
Yew Chong Yap, Thomas Papathomas, Ahmed Kamal
AIM: To evaluate the safety and efficacy of dexamethasone implant in patients with non-infectious posterior uveitis with cystoid macular edema (CME). METHODS: Retrospective analysis of patients reports with CME secondary to non-infectious uveitis treated with dexamethasone implant. Data included type of posterior uveitis, any systemic immunosuppressive therapy, Early Treatment Diabetic Retinopathy Study (ETDRS) best-corrected visual acuity (BCVA), central macular thickness (CMT) on optical coherence tomography (OCT) and signs of intraocular inflammation at baseline and then at 2wk postoperatively and monthly thereafter...
2015: International Journal of Ophthalmology
https://www.readbyqxmd.com/read/26309876/clinical-characteristics-of-intermediate-uveitis-in-adult-turkish-patients
#18
Esra Kardes, Betül Ilkay Sezgin Akcay, Kansu Bozkurt, Cihan Unlu, Gurkan Erdogan, Gulunay Akcali
AIM: To describe the clinical characteristics of Turkish patients with intermediate uveitis (IU) and to investigate the effect of clinical findings and complications on final visual acuity (VA). METHODS: We retrospectively analyzed the medical records of patients with IU who had at least 6mo of follow-up and were older than 16y. RESULTS: A total of 78 eyes of 45 patients were included in the study and the mean follow-up period was 19.4mo. The mean age at the time of presentation was 42...
2015: International Journal of Ophthalmology
https://www.readbyqxmd.com/read/26255577/the-association-of-race-with-childhood-uveitis
#19
Sheila T Angeles-Han, Courtney McCracken, Steven Yeh, Kirsten Jenkins, Daneka Stryker, Curtis Travers, Kelly Rouster-Stevens, Larry B Vogler, Scott R Lambert, Carolyn Drews-Botsch, Sampath Prahalad
PURPOSE: To identify risk factors for a severe uveitis course among children with noninfectious uveitis. DESIGN: Retrospective cohort study. METHOD: This was a retrospective analysis of a prospectively collected database. Records of 94 children with uveitis were reviewed at enrollment and every 3-6 months (2011-2015). Severe uveitis was defined as a history of ocular complications or a visual acuity (VA) of ≤20/200. Children were compared by disease, VA, complications, and race...
November 2015: American Journal of Ophthalmology
https://www.readbyqxmd.com/read/26233598/acute-anterior-uveitis-and-spondyloarthritis-more-than-meets-the-eye
#20
REVIEW
Muhammad A Khan, Muhammad Haroon, James T Rosenbaum
Ankylosing spondylitis (AS) and related forms of spondyloarthritis (SpA) are associated with some extra-articular features, and the most common symptomatic association is with acute anterior uveitis (AAU). Thus, approximately 40 % of patients with AS will experience a sudden onset of a unilateral anterior uveitis sometime during the course of their disease. Patients with AAU, especially those who are HLA-B27 positive, should be questioned about inflammatory low back pain and also evaluated for other clinical features of SpA...
September 2015: Current Rheumatology Reports
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