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Allergic bronchopulmonary aspergillosis

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https://www.readbyqxmd.com/read/28370596/identifying-rare-diseases-using-electronic-medical-records-the-example-of-allergic-bronchopulmonary-aspergillosis
#1
Andrew Maguire, Michelle E Johnson, David W Denning, Germano L C Ferreira, Adrian Cassidy
PURPOSE: The purpose of the study is to evaluate whether primary care electronic medical records (EMRs) from patients with severe asthma can be used to identify allergic bronchopulmonary aspergillosis (ABPA) cases. METHODS: This cross-sectional feasibility study was conducted in adults with active and severe asthma registered with the Clinical Practice Research Datalink. A set of keywords flagged terms potentially indicative of ABPA in free-text comments of patients' EMRs to produce a grid on the basis of keywords' hit or miss...
March 31, 2017: Pharmacoepidemiology and Drug Safety
https://www.readbyqxmd.com/read/28360463/prevalence-of-aspergillus-hypersensitivity-and-allergic-bronchopulmonary-aspergillosis-in-patients-with-bronchial-asthma-at-a-tertiary-care-center-in-north-india
#2
Alok Nath, Ajmal Khan, Zia Hashim, Jeetendra Kumar Patra
BACKGROUND: The prevalence of Aspergillus hypersensitivity (AH) and allergic bronchopulmonary aspergillosis (ABPA) has been variably reported. Systematic data regarding Aspergillus sensitization and ABPA are lacking from this part of the country. OBJECTIVES: The aim of this study was to evaluate the prevalence of AH and ABPA in Uttar Pradesh. SETTING AND DESIGN: This was prospective observational study. All patients attending outpatient Department of Pulmonary Medicine of our institute were included in the study...
March 2017: Lung India: Official Organ of Indian Chest Society
https://www.readbyqxmd.com/read/28328160/co-morbidities-in-severe-asthma-clinical-impact-and-management
#3
REVIEW
Celeste Porsbjerg, Andrew Menzies-Gow
Patients with severe asthma represent a minority of the total asthma population, but carry a majority of the morbidity and healthcare costs. Achieving better asthma control in this group of patients is therefore of key importance. Systematic assessment of patients with possible severe asthma to identify treatment barriers and triggers of asthma symptoms, including co-morbidities, improves asthma control and reduces healthcare costs and is recommended by international guidelines on management of severe asthma...
March 22, 2017: Respirology: Official Journal of the Asian Pacific Society of Respirology
https://www.readbyqxmd.com/read/28325727/effect-of-allergic-bronchopulmonary-aspergillosis-on-fev1-in-children-and-adolescents-with-cystic-fibrosis-a-european-cystic-fibrosis-society-patient-registry-analysis
#4
Athanasios G Kaditis, Michael Miligkos, Anna Bossi, Carla Colombo, Elpis Hatziagorou, Nataliya Kashirskaya, Isabelle de Monestrol, Muriel Thomas, Meir Mei-Zahav, George Chrousos, Anna Zolin
OBJECTIVE: To evaluate the effect of allergic bronchopulmonary aspergillosis (ABPA) on FEV1 percent predicted in children and adolescents with cystic fibrosis. DESIGN: Longitudinal data analysis (2008-2010). SETTING: Patients participating in the European Cystic Fibrosis Society Patient Registry. PARTICIPANTS: 3350 patients aged 6-17 years. MAIN OUTCOME MEASURE: FEV1percent predicted was the main outcome measure (one measurement per year per child)...
March 21, 2017: Archives of Disease in Childhood
https://www.readbyqxmd.com/read/28320038/-allergic-bronchopulmonary-aspergillosis
#5
Günter Menz, Hans-Werner Duchna
No abstract text is available yet for this article.
March 2017: Pneumologie
https://www.readbyqxmd.com/read/28299723/mold-and-human-health-a-reality-check
#6
REVIEW
Andrea T Borchers, Christopher Chang, M Eric Gershwin
There are possibly millions of mold species on earth. The vast majority of these mold spores live in harmony with humans, rarely causing disease. The rare species that does cause disease does so by triggering allergies or asthma, or may be involved in hypersensitivity diseases such as allergic bronchopulmonary aspergillosis or allergic fungal sinusitis. Other hypersensitivity diseases include those related to occupational or domiciliary exposures to certain mold species, as in the case of Pigeon Breeder's disease, Farmer's lung, or humidifier fever...
March 16, 2017: Clinical Reviews in Allergy & Immunology
https://www.readbyqxmd.com/read/28279664/combination-omalizumab-and-mepolizumab-therapy-for-refractory-allergic-bronchopulmonary-aspergillosis
#7
Matthew C Altman, Jake Lenington, Steve Bronson, Andrew G Ayars
No abstract text is available yet for this article.
March 6, 2017: Journal of Allergy and Clinical Immunology in Practice
https://www.readbyqxmd.com/read/28258742/current-and-future-approaches-to-large-airways-imaging-in-adults-and-children
#8
REVIEW
T Semple, A Calder, C M Owens, S Padley
"Large airways disease" is a catch-all phrase encompassing a wide variety of pathology affecting the trachea, main, lobar, segmental, and proximal sub-segmental bronchi. Relevant pathologies can be divided into focal or diffuse processes and many conditions have classic appearances on computed tomography (CT). We provide a review of the imaging specifics of a wide range of large airway pathologies in adult, childhood, and fetal life with examples of common and rare pathologies ranging from well-known entities such as cystic fibrosis and allergic bronchopulmonary aspergillosis to rarities such as Williams-Campbell, primary ciliary dyskinesia, and congenital high-airway obstruction syndrome (CHAOS)...
May 2017: Clinical Radiology
https://www.readbyqxmd.com/read/28243758/burden-of-serious-fungal-infections-in-guatemala
#9
N Medina, B Samayoa, D Lau-Bonilla, D W Denning, R Herrera, D Mercado, B Guzmán, J C Pérez, E Arathoon
Guatemala is a developing country in Central America with a high burden of HIV and endemic fungal infections; we attempted to estimate the burden of serious fungal infections for the country. A full literature search was done to identify epidemiology papers reporting fungal infections from Guatemala. We used specific populations at risk and fungal infection frequencies in the population to estimate national rates. The population of Guatemala in 2013 was 15.4 million; 40% were younger than 15 and 6.2% older than 60...
February 27, 2017: European Journal of Clinical Microbiology & Infectious Diseases
https://www.readbyqxmd.com/read/28220322/serious-fungal-infections-in-the-philippines
#10
M C R Batac, D Denning
The Philippines is a low middle-income, tropical country in Southeast Asia. Infectious diseases remain the main causes of morbidity, including tuberculosis. AIDS/HIV prevalence is still low at <1%, but is rapidly increasing. Fungal disease surveillance has not been done, and its burden has never been estimated. This becomes more important as the population of immunocompromised patients increases, drawn from patients with AIDS, TB, malignancies, and autoimmune diseases requiring chronic steroid use. Using the methodology of the LIFE program ( www...
February 21, 2017: European Journal of Clinical Microbiology & Infectious Diseases
https://www.readbyqxmd.com/read/28202251/high-incidence-of-non-tuberculous-mycobacteria-positive-cultures-among-adolescent-with-cystic-fibrosis
#11
Zoé Cavalli, Quitterie Reynaud, Romain Bricca, Raphaële Nove-Josserand, Stéphane Durupt, Philippe Reix, Marie Perceval, Michèle Pérouse de Montclos, Gérard Lina, Isabelle Durieu
BACKGROUND: We evaluated the prevalence of non-tuberculous mycobacteria (NTM)-positive cultures among our cystic fibrosis (CF) center patients, reviewed risk factors for NTM positivity, and determined its impact on lung function evolution. METHODS: From 2009 to 2014, CF adults and children attending the CF center of Lyon (France) and having at least one positive NTM isolate were included. Each case was matched by age and gender with two CF patients with no NTM isolate (controls)...
February 12, 2017: Journal of Cystic Fibrosis: Official Journal of the European Cystic Fibrosis Society
https://www.readbyqxmd.com/read/28188493/serious-fungal-infections-in-chile
#12
E Alvarez Duarte, D W Denning
The incidence and prevalence of fungal infections in Chile are unknown. Here, we have estimated the burden of serious fungal diseases from data obtained from clinical reports, WHO reports, Chilean census, OECD reports and comprehensive literature search available on PubMed and SciELO, among other scientific resources. Due the lack of official data about fungal diseases, frequencies were calculated based on the specific populations at risk. Recurrent vulvovaginal candidiasis (>4 episodes/year) is estimated to occur in 3108/100,000...
February 10, 2017: European Journal of Clinical Microbiology & Infectious Diseases
https://www.readbyqxmd.com/read/28188492/serious-fungal-infections-in-portugal
#13
R Sabino, C Verissímo, J Brandão, C Martins, D Alves, C Pais, D W Denning
There is a lack of knowledge on the epidemiology of fungal infections worldwide because there are no reporting obligations. The aim of this study was to estimate the burden of fungal disease in Portugal as part of a global fungal burden project. Most published epidemiology papers reporting fungal infection rates from Portugal were identified. Where no data existed, specific populations at risk and fungal infection frequencies in those populations were used in order to estimate national incidence or prevalence, depending on the condition...
February 10, 2017: European Journal of Clinical Microbiology & Infectious Diseases
https://www.readbyqxmd.com/read/28188491/serious-fungal-infections-in-peru
#14
B Bustamante, D W Denning, P E Campos
Epidemiological data about mycotic diseases are limited in Peru and estimation of the fungal burden has not been previously attempted. Data were obtained from the Peruvian National Institute of Statistics and Informatics, UNAIDS and from the Ministry of Health's publications. We also searched the bibliography for Peruvian data on mycotic diseases, asthma, COPD, cancer and transplants. Incidence or prevalence for each fungal disease were estimated in specific populations at risk. The Peruvian population for 2015 was 31,151,543...
February 10, 2017: European Journal of Clinical Microbiology & Infectious Diseases
https://www.readbyqxmd.com/read/28178715/infectious-causes-of-right-middle-lobe-syndrome
#15
Aatif Rashid, Sowmya Nanjappa, John N Greene
Right middle lobe (RML) syndrome is defined as recurrent or chronic obstruction or infection of the middle lobe of the right lung. Nonobstructive causes of middle lobe syndrome include inflammatory processes and defects in the bronchial anatomy and collateral ventilation. We report on 2 case patients with RML syndrome, one due to infection with Mycobacterium avium complex followed by M asiaticum infection and the other due to allergic bronchopulmonary aspergillosis. A history of atopy, asthma, or chronic obstructive pulmonary disease has been reported in up to one-half of those with RML...
January 2017: Cancer Control: Journal of the Moffitt Cancer Center
https://www.readbyqxmd.com/read/28178337/prospective-multicenter-german-study-on-pulmonary-colonization-with-scedosporium-lomentospora-species-in-cystic-fibrosis-epidemiology-and-new-association-factors
#16
Carsten Schwarz, Claudia Brandt, Elisabeth Antweiler, Alexander Krannich, Doris Staab, Sabina Schmitt-Grohé, Rainald Fischer, Dominik Hartl, Anja Thronicke, Kathrin Tintelnot
BACKGROUND: An increasing rate of respiratory colonization and infection in cystic fibrosis (CF) is caused by fungi of the Scedosporium apiospermum species complex or Lomentospora prolificans (Sac-Lp). These fungi rank second among the filamentous fungi colonizing the CF airways, after Aspergillus fumigatus. However, the epidemiology, clinical relevance and risk of pulmonary colonization with Sac-Lp are rarely understood in CF. The objective of the present prospective multicenter study was to study pathogen distribution and determine association factors of pulmonary Sac-Lp colonization in patients with CF...
2017: PloS One
https://www.readbyqxmd.com/read/28166077/a-rare-case-of-bilateral-aspergillomas-in-a-patient-of-ankylosing-spondylitis
#17
A Das, S Pandit, S K Das, S Basuthakur, S Das
Pulmonary involvement by Aspergillus sp. mainly includes allergic bronchopulmonary aspergillosis, aspergilloma, and invasive aspergillosis. Aspergilloma (Fungal ball) is the most common form of aspergillous pulmonary involvement, which occurs in preexisting pulmonary cavities, especially secondary to pulmonary tuberculosis. Ankylosing spondylitis is a rare cause of upper lobe fibro-cavitary lesions in pulmonary parenchyma. It may also lead to development of fungal balls in pulmonary cavities. Most common presentation is mild to massive hemoptysis; dyspnoea, chronic cough, expectoration may be other presentation; even the patient may remain asymptomatic...
April 2016: Kathmandu University Medical Journal (KUMJ)
https://www.readbyqxmd.com/read/28161745/serious-fungal-infections-in-canada
#18
S F Dufresne, D C Cole, D W Denning, D C Sheppard
There are currently no nationwide epidemiological data on fungal infections in Canada. We estimated the burden of serious fungal diseases using literature review and modeling, as per a methodology previously described by the LIFE program ( http://www.LIFE-worldwide.org ). Among the population of Canada (35.5 million in 2014), it was estimated that approximately 1.8% are affected by a serious fungal infection. Recurrent vulvovaginal candidiasis, severe asthma with fungal sensitization, and allergic bronchopulmonary aspergillosis are the most frequent infections, with population prevalences of 498,688 (1403/100,000), 73,344 (206/100,000), and 61,854 (174/100,000) cases, respectively...
February 4, 2017: European Journal of Clinical Microbiology & Infectious Diseases
https://www.readbyqxmd.com/read/28161744/burden-of-serious-fungal-infections-in-bangladesh
#19
H C Gugnani, D W Denning, R Rahim, A Sadat, M Belal, M S Mahbub
In Bangladesh there are several published papers on superficial mycoses. Deep mycoses are also recognized as an important emerging problem. Here, we estimate the annual incidence and prevalence of serious fungal infections in Bangladesh. Demographic data were obtained from world population reports and the data on TB and HIV extracted from the online publications on tuberculosis in Bangladesh and Asia Pacific research statistical data information resources AIDS Data HUB. All the published papers on fungal infections in Bangladesh were identified through extensive search of literature...
February 4, 2017: European Journal of Clinical Microbiology & Infectious Diseases
https://www.readbyqxmd.com/read/28161743/serious-fungal-infections-in-korea
#20
K Huh, Y E Ha, D W Denning, K R Peck
Information on the incidence and prevalence of fungal infections is of critical value in public health policy. However, nationwide epidemiological data on fungal infections are scarce, due to a lack of surveillance and funding. The objective of this study was to estimate the disease burden of fungal infections in the Republic of Korea. An actuarial approach using a deterministic model was used for the estimation. Data on the number of populations at risk and the frequencies of fungal infections in those populations were obtained from national statistics reports and epidemiology papers...
February 4, 2017: European Journal of Clinical Microbiology & Infectious Diseases
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