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https://www.readbyqxmd.com/read/28793953/the-spectrum-of-biopsy-proven-secondary-glomerular-diseases-a-cross-sectional-study-in-china%C3%A2
#1
Ping Wang, Lijun Tang, Jing Yao, Hong Su, Yipeng Liu, Xianglei Kong, Wenbin Li, Meiyu Cui, Qing Sun, Junhui Zhen, Dongmei Xu
AIMS: The distribution of the spectrum of chronic kidney disease (CKD) has been found to vary with time. Limited information is available regarding the changing spectrum of secondary glomerular diseases (SGDs). To further investigate changes in the spectrum of SGDs, we performed a cross-sectional study. METHODS: From June 2010 to May 2015, 5,935 patients from 37 hospitals in Shandong Province were involved in this study. The study was divided into five periods according to 1-year intervals...
August 10, 2017: Clinical Nephrology
https://www.readbyqxmd.com/read/28781836/urticaria-vasculitis-in-a-child-a-case-report-and-literature-review
#2
Adrián Imbernón-Moya, Elena Vargas-Laguna, Fernando Burgos, Eva Fernández-Cogolludo, Antonio Aguilar-Martínez, Miguel Ángel Gallego-Valdés
Annular urticarial lesions in a child must establish a main differential diagnosis with urticaria multiforme, common urticaria, acute hemorrhagic edema of infancy, erythema marginatum, erythema annulare centrifugum, annular erythema in childhood, erythema multiforme, Sweet's syndrome, Schönlein-Henoch purpura, erythematosus lupus, several systemic vasculitis, and serum sickness.
August 2017: Clinical Case Reports
https://www.readbyqxmd.com/read/28774183/annals-express-altered-mean-platelet-volume-in-children-with-henoch-schonlein-purpura-and-its-association-with-disease-activity
#3
Xiang Shi, Wen Chao Li, Li Jun Mo, Xiao Hong Li, Yu Zhen Luo, Liu Qun Qin, Zheng Yang, Wu Ning Mo
BACKGROUND: Henoch-Schonlein purpura (HSP) is a systemic small-vessel vasculitis that occurs mainly in children. A review of the literature has suggested a correlation between mean platelet volume (MPV) and several inflammatory disorders. However, to the best of our knowledge, any potential correlation between MPV and HSP has not been reported in the literature. Therefore, our study aimed to evaluate the role of MPV levels in patients with HSP. METHODS: This study included 97 children with HSP and 120 healthy individuals as controls...
January 1, 2017: Annals of Clinical Biochemistry
https://www.readbyqxmd.com/read/28771805/cutaneous-small-vessel-vasculitis-in-two-children-with-inflammatory-bowel-disease-case-series-and-review-of-the-literature
#4
Tina Ho, Lauren A V Orenstein, Markus D Boos, Kevin P White, Nicole Fett
Cutaneous small-vessel vasculitis (CSVV) is an infrequent manifestation of pediatric inflammatory bowel disease (IBD). We report two cases of CSVV associated with ulcerative colitis, review the literature, and discuss the diagnostic evaluation of children who present with CSVV and abdominal pain. After excluding more common causes of CSVV and abdominal pain in children, including immunoglobulin A vasculitis (previously Henoch-Schönlein purpura), infectious colitis, and drug-induced vasculitis, alternative diagnoses such as CSVV secondary to IBD or systemic vasculitis with gastrointestinal involvement must be considered...
August 2, 2017: Pediatric Dermatology
https://www.readbyqxmd.com/read/28761605/henoch-schonlein-purpura-associated-with-primary-active-epstein-barr-virus-infection-a-case-report
#5
Burcu Karakayali, Sila Yilmaz, Deniz Çakir, Pembe Gül Günes, Sirin Güven, Ismail Islek
Henoch-Schönlein purpura (HSP) is the most common form of childhood vasculitis. Various viral and bacterial infections, drugs, vaccines, food allergy and even insect bites have been considered as triggering factors in pathogenesis of HSP. Epstein-Barr virus (EBV) infection, which is associated with HSP, have been rarely reported. Herein we present HSP patient possibly caused by EBV infection. A 8-year old boy was admitted to our department with fever, rashes on legs and arms and intermittent mild abdominal pain...
2017: Pan African Medical Journal
https://www.readbyqxmd.com/read/28754494/safety-and-immunogenicity-of-a-mrna-rabies-vaccine-in-healthy-adults-an-open-label-non-randomised-prospective-first-in-human-phase-1-clinical-trial
#6
Martin Alberer, Ulrike Gnad-Vogt, Henoch Sangjoon Hong, Keyvan Tadjalli Mehr, Linus Backert, Greg Finak, Raphael Gottardo, Mihai Alexandru Bica, Aurelio Garofano, Sven Dominik Koch, Mariola Fotin-Mleczek, Ingmar Hoerr, Ralf Clemens, Frank von Sonnenburg
BACKGROUND: Vaccines based on mRNA coding for antigens have been shown to be safe and immunogenic in preclinical models. We aimed to report results of the first-in-human proof-of-concept clinical trial in healthy adults of a prophylactic mRNA-based vaccine encoding rabies virus glycoprotein (CV7201). METHODS: We did an open-label, uncontrolled, prospective, phase 1 clinical trial at one centre in Munich, Germany. Healthy male and female volunteers (aged 18-40 years) with no history of rabies vaccination were sequentially enrolled...
July 25, 2017: Lancet
https://www.readbyqxmd.com/read/28731865/-joining-the-spots-in-adults-and-young-tots-a-clinicopathological-study-of-henoch-sch%C3%A3-nlein-purpura-iga-vasculitis
#7
Priyanka P Kedia, Rajalakshmi Tirumalae, Divya Puttegowda, Meryl Antony
INTRODUCTION: Henoch-Schönlein Purpura (HSP; IgA vasculitis), the most common vasculitis of childhood, has a wide spectrum of clinical manifestations ranging from palpable purpura with abdominal pain and arthritis to the more morbid renal involvement. AIMS AND OBJECTIVES: To study and correlate the clinical presentation, laboratory values, skin and renal histopathology and immunofluoroscence findings in HSP. MATERIAL AND METHODS: A total of 44 cases of HSP from March 2011 to February 2014 were studied for the above features along with their clinical outcomes...
August 2017: American Journal of Dermatopathology
https://www.readbyqxmd.com/read/28731667/-henoch-schonlein-purpura-involving-the-penis-a-case-report
#8
Borja Croche Santander, Elena Campos, Adela Sánchez, Laura Marcos, Isabel Díaz, Cristóbal Toro
Schonlein-Henoch purpura accounts for the majority of cases of systemic vasculitis in children. Classical presentation is characterized by palpable purpura, glomerulonephritis, arthralgias and abdominal pain. Although genitourinary manifestations, in form of testicular and scrotal involvement, have been widely described, penile involvement remains an extremely rare complication. We report a case of a 6-year-old boy who presented with purpuric rash on the glans, prepuce and penile shaft, with painful edema in the penile region...
August 1, 2017: Archivos Argentinos de Pediatría
https://www.readbyqxmd.com/read/28711558/four-cancers-and-a-rash-henoch-sch%C3%A3-nlein-purpura
#9
Richard K Kim, Alyssa R Thomas, Mary Elizabeth Card, Divyanshu Malhotra, Jürgen L Holleck
No abstract text is available yet for this article.
July 12, 2017: American Journal of Medicine
https://www.readbyqxmd.com/read/28709416/warfarin-induced-toxic-epidermal-necrolysis-in-combination-therapy-of-henoch-sch%C3%A3-nlein-purpura-nephritis-a-case-report
#10
Katsuaki Kasahara, Yoshimitsu Gotoh, Yoshiyuki Kuroyanagi, China Nagano
BACKGROUND: Toxic epidermal necrolysis (TEN) is a rare life-threatening condition almost exclusively attributed to drugs. The main etiologic factors for TEN are sulphonamides, anticonvulsants, and antibiotics; however, there are no published reports of warfarin causing TEN. CASE PRESENTATION: We present the case of a 3-year-old patient who developed TEN while receiving treatment for Henoch-Schönlein purpura nephritis (HSPN). With multiple-drug therapy comprising prednisolone, mizoribine, dipyridamole, and warfarin, it is difficult to detect which drug is the causative agent...
July 14, 2017: BMC Nephrology
https://www.readbyqxmd.com/read/28702966/possible-role-of-helicobacter-pylori-in-diseases-of-dermatological-interest
#11
C Guarneri, J Lotti, M Fioranelli, M G Roccia, T Lotti, F Guarneri
Helicobacter pylori is a gram-negative, flagellate, microaerophilic bacterium identified for the first time about 30 years ago, as a pathogenic factor of gastritis and peptic ulcer. Soon after, it was linked to several gastrointestinal and extra-gastrointestinal diseases (hematological, cardiovascular, neurological, pulmonary and ocular diseases, obesity, diabetes mellitus, growth retardation and extragastric MALT lymphoma). Association and possible cause-effect correlation with H. pylori infection were suggested in diseases of dermatological interest such as chronic urticaria, rosacea, Henoch-Schoenleins purpura, idiopathic thrombocytopenic purpura, cutaneous and oral lichen planus, atopic dermatitis, recurrent aphthous stomatitis, systemic sclerosis, psoriasis, Sjögrens syndrome, Behçet's disease, pruritus, alopecia areata, primary cutaneous marginal zone B-cell lymphomas, vitiligo, chronic prurigo, multiformis, prurigo nodularis, leukocytoclastic vasculitis, prurigo pigmentosa, eczema nummulare, primary cutaneous MALT-type lymphoma, sublamina densa-type linear IgA bullous dermatosis, Sweet's syndrome, cutaneous T-cell pseudolymphoma and pemphigus vulgaris...
April 2017: Journal of Biological Regulators and Homeostatic Agents
https://www.readbyqxmd.com/read/28700526/urinary-macrophage-migration-inhibitory-factor-as-a-noninvasive-biomarker-in-pediatric-henoch-sch%C3%A3-nlein-purpura-nephritis
#12
Jiapei Wang, Yunyan Li, Yuanling Chen, Xiahua Dai, Yazhen Di, Mengjiao Shen, Qianqian Ying, Shiwei Fu, Yinjie Li
PURPOSES: The aims of this study were to investigate urinary macrophage migration inhibitory factor (MIF) levels and their clinical significance in Henoch-Schönlein purpura (HSP) children with or without nephritis (N) and to assess the influence of steroid treatment on the urine MIF levels of HSPN patients. METHODS: Group I comprised 35 children with HSPN who were examined twice (A before treatment and B after steroid treatment). Group II comprised 41 children with HSP...
August 2017: Journal of Clinical Rheumatology: Practical Reports on Rheumatic & Musculoskeletal Diseases
https://www.readbyqxmd.com/read/28697838/-hypertension-and-intermittent-convulsions-for-one-month-in-a-school-age-child
#13
Mao-Qiang Tian, Shu-Yi Liu, Juan Li, Xiao-Mei Shu
Childhood polyarteritis nodosa (PAN) is a rare systemic vasculitis and the delayed diagnosis and treatment will cause high incidence of sequelae and high mortality. This article reports a girl with childhood PAN due to posterior reversible encephalopathy syndrome (PRES). The girl aged ten years was admitted to the hospital due to hypertension and convulsions for one month. She had complaints of headache, vomiting, and blurred vision before convulsions. At six months before admission, a mass was observed in the neck...
July 2017: Zhongguo Dang Dai Er Ke za Zhi, Chinese Journal of Contemporary Pediatrics
https://www.readbyqxmd.com/read/28697834/-association-of-serum-vitamin-d-level-with-severity-and-treatment-in-children-with-henoch-sch%C3%A3-nlein-purpura
#14
Li Fan, Heng Liu, Yu-Chuan Wang, Li Chen, Jing-Jing Zhou, Yu-Xia Cui
OBJECTIVE: To investigate the association of serum vitamin D [25-(OH)D3] level with the severity and treatment in children with Henoch-Schönlein purpura (HSP). METHODS: A total of 50 children with newly-diagnosed HSP between January and December, 2015 were enrolled as HSP group, and 49 healthy children were enrolled as control group. Fasting serum samples were collected, and ELISA was used to measure serum 25-(OH)D3 level. According to the serum 25-(OH)D3 level, the HSP group were further divided into normal group (>20 ng/mL) (n=9), insufficiency group (15-20 ng/mL) (n=15), deficiency group (≤15 ng/mL) (n=25), and severe deficiency group (≤5 ng/mL) (n=1)...
July 2017: Zhongguo Dang Dai Er Ke za Zhi, Chinese Journal of Contemporary Pediatrics
https://www.readbyqxmd.com/read/28691415/association-of-ace-vegf-and-ccl2-gene-polymorphisms-with-henoch-schonlein-purpura-and-evaluating-the-possible-interaction-effects-of-these-loci-in-hsp-patients
#15
Tahereh Mohammadian, Mortaza Bonyadi, Elahe Nabat, Mandana Rafeey
BACKGROUND: Henoch-Schonlein purpura (HSP) is a multisystem, small vessel, leucocytoclastic vasculitis. It is predominantly a childhood vasculitis, rarely reported in adults. Studies have shown that several different genetic factors such as genes involved in inflammatory system and renin-angiotensin system (RAS) are important in the pathogenesis of Henoch-Schönlein purpura. OBJECTIVES: The purpose of this study was to evaluate the independent effect of three gene polymorphisms including CCL2-2518 C/T, VEGF-634G/C and ACE(I/D) with HSP disease and their possible joint interactions in developing the disease...
June 27, 2017: Advances in Clinical and Experimental Medicine: Official Organ Wroclaw Medical University
https://www.readbyqxmd.com/read/28680829/azathioprine-treatment-in-two-children-with-henoch-sch%C3%A3-nlein-purpura-nephritis
#16
COMMENT
Meltem A Melikoğlu, Mehmet Melikoğlu, Emine E Ergul
No abstract text is available yet for this article.
June 2017: Kidney Research and Clinical Practice
https://www.readbyqxmd.com/read/28678983/prevalence-and-characteristics-of-nonblanching-palpable-skin-lesions-with-a-linear-pattern-in-children-with-henoch-sch%C3%A3-nlein-syndrome
#17
Gregorio P Milani, Sebastiano A G Lava, Vera Ramelli, Mario G Bianchetti
Importance: Linear nonblanching skin lesions are thought to occur very rarely in patients with Henoch-Schönlein syndrome. Objective: To examine the prevalence and characteristics of linear nonblanching skin lesions in children with Henoch-Schönlein syndrome. Design, Setting, and Participants: A prospective case series was conducted at the ambulatory practice of a hospitalist between January 1, 2010, and December 31, 2015, among 31 consecutive children with Henoch-Schönlein syndrome...
July 5, 2017: JAMA Dermatology
https://www.readbyqxmd.com/read/28661927/koebner-phenomenon-in-a-young-boy-with-henoch-sch%C3%A3-nlein-purpura
#18
Ankur Kumar Jindal, Anju Gupta, Ranjana W Minz
No abstract text is available yet for this article.
August 2017: Journal of Clinical Rheumatology: Practical Reports on Rheumatic & Musculoskeletal Diseases
https://www.readbyqxmd.com/read/28654132/henoch-sch%C3%A3-nlein-purpura-a-literature-review
#19
Liv Eline Hetland, Kjærsti Sørensen Susrud, Kim Hein Lindahl, Anette Bygum
Henoch-Schönlein purpura is the most common childhood vasculitis, but may also affect adults. This article reviews the literature since 2011 on advances in diagnosis, clinical disease manifestations, pathophysiology and treatment of Henoch-Schönlein purpura. The clinical manifestations are thought to arise from IgA depositions in blood vessel walls in the affected organs, mostly skin, gastrointestinal tract, joints and kidneys. Corticosteroids may be effective in rapid resolution of renal manifestations and treating joint and abdominal pain, but they are not proven effective for treating organ manifestations and complications, such as glomerulonephritis, bowel infarction or intussusception...
June 27, 2017: Acta Dermato-venereologica
https://www.readbyqxmd.com/read/28648955/undergraduate-nursing-students-attitudes-and-preparedness-toward-caring-for-dying-persons-a-longitudinal-study
#20
Ingela Henoch, Christina Melin-Johansson, Ingrid Bergh, Susann Strang, Kristina Ek, Kina Hammarlund, Carina Lundh Hagelin, Lars Westin, Jane Österlind, Maria Browall
Nursing education needs to prepare students for care of dying patients. The aim of this study was to describe the development of nursing students' attitudes toward caring for dying patients and their perceived preparedness to perform end-of-life care. A longitudinal study was performed with 117 nursing students at six universities in Sweden. The students completed the Frommelt Attitude Toward Care of the Dying Scale (FATCOD) questionnaire at the beginning of first and second year, and at the end of third year of education...
June 17, 2017: Nurse Education in Practice
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