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Transcatheter mitral valve repair

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https://www.readbyqxmd.com/read/28398395/-transcatheter-mitral-valve-repair-for-patients-not-amenable-to-surgical-correction-epidemiology-diagnosis-equiti-of-access-and-economic-impact
#1
Francesco Bedogni, Sergio Berti, Giovanni Esposito, Alessio Gaetano La Manna, Ugo Limbruno, Alfredo Marchese, Ciro Mauro, Alessandro Salvi, Gennaro Santoro, Giuseppe Tarantini, Fabio Tarantino, Ferdinando Varbella, Roberto Violini, Giuseppe Musumeci
Mitral regurgitation is the most common valvular heart disease in western world, with moderate to severe mitral regurgitation having a deep impact on prognosis, mortality and rehospitalizations. Advanced congestive heart failure is frequently complicated by mitral regurgitation, a pathologic condition that is often under-diagnosed. A significant proportion of patients with severe mitral regurgitation is not eligible for surgery (mitral valve repair or replacement) because of contraindications or excessive surgical risk...
February 2017: Giornale Italiano di Cardiologia
https://www.readbyqxmd.com/read/28378353/reduction-of-left-ventricular-outflow-tract-obstruction-with-transcatheter-mitral-valve-repair
#2
Megan Coylewright, Elizabeth S O'Neill, John F Robb, Jock N McCullough, Cassie M Tighe, Joshua M Callahan, Timothy A Beaver
Many patients with severe mitral regurgitation cannot undergo conventional mitral valve surgery due to prohibitive surgical risk and are candidates for transcatheter repair with an edge-to-edge technique. Prior reports suggest efficacy with this approach for mitral regurgitation due to hypertrophic cardiomyopathy with left ventricular outflow obstruction. We present a case report of transcatheter mitral valve repair for posterior leaflet prolapse with concomitant left ventricular outflow tract obstruction due to systolic anterior motion of the mitral valve in the absence of hypertrophic cardiomyopathy...
April 2017: Echocardiography
https://www.readbyqxmd.com/read/28374279/design-analysis-and-testing-of-a-novel-mitral-valve-for-transcatheter-implantation
#3
Selim Bozkurt, Georgia L Preston-Maher, Ryo Torii, Gaetano Burriesci
Mitral regurgitation is a common mitral valve dysfunction which may lead to heart failure. Because of the rapid aging of the population, conventional surgical repair and replacement of the pathological valve are often unsuitable for about half of symptomatic patients, who are judged high-risk. Transcatheter valve implantation could represent an effective solution. However, currently available aortic valve devices are inapt for the mitral position. This paper presents the design, development and hydrodynamic assessment of a novel bi-leaflet mitral valve suitable for transcatheter implantation...
April 3, 2017: Annals of Biomedical Engineering
https://www.readbyqxmd.com/read/28374178/current-status-of-catheter-based-treatment-of-mitral-valve-regurgitation
#4
REVIEW
Mario Gössl, Robert S Farivar, Richard Bae, Paul Sorajja
PURPOSE OF REVIEW: This review examines the current status of catheter-based repair and replacement for mitral valve disease, with a focus on native primary and secondary mitral valve regurgitation. RECENT FINDINGS: Transcatheter mitral valve repair with the MitraClip®, with >40,000 performed procedures worldwide, has significantly advanced the field of transcatheter therapy for mitral valve regurgitation. Transcatheter mitral valve replacement remains in the early stages of development, mainly due to the complex anatomy and physiology of the mitral valve...
May 2017: Current Cardiology Reports
https://www.readbyqxmd.com/read/28370526/predictors-for-long-term-survival-after-transcatheter-edge-to-edge-mitral-valve-repair
#5
Mathias Orban, Martin Orban, Hasema Lesevic, Daniel Braun, Simon Deseive, Carolin Sonne, Lisa Hutterer, Christian Grebmer, Alexander Khandoga, Jürgen Pache, Julinda Mehilli, Heribert Schunkert, Adnan Kastrati, Christian Hagl, Axel Bauer, Steffen Massberg, Peter Boekstegers, Michael Nabauer, Ilka Ott, Jörg Hausleiter
OBJECTIVES: To determine predictors for long-term outcome in high-risk patients undergoing transcatheter edge-to-edge mitral valve repair (TMVR) for severe mitral regurgitation (MR). BACKGROUND: There is no data on predictors of long-term outcome in high-risk real-world patients. METHODS: From August 2009 to April 2011, 126 high-risk patients deemed inoperable were treated with TMVR in two high-volume university centers. RESULTS: MR could be successfully reduced to grade ≤2 in 92...
March 28, 2017: Journal of Interventional Cardiology
https://www.readbyqxmd.com/read/28364394/transcatheter-mitral-valve-interventions-current-therapies-and-future-directions
#6
REVIEW
Ramon A Partida, Sammy Elmariah
Transcatheter interventions for the treatment of aortic valve stenosis have become commonplace since the advent of transcatheter aortic valve implantation. However, transcatheter mitral valve therapies have lagged in development due to the complexity of mitral valve anatomy. Transcatheter edge-to-edge leaflet repair using the MitraClip device provides an option for the treatment of severe primary mitral valve regurgitation in high or prohibitive surgical risk patients, and multiple novel approaches are evolving to replace or repair the mitral valve...
May 2017: Current Treatment Options in Cardiovascular Medicine
https://www.readbyqxmd.com/read/28336788/transcatheter-treatment-of-severe-tricuspid-regurgitation-with-the-edge-to-edge-mitraclip-technique
#7
Georg Nickenig, Marek Kowalski, Jörg Hausleiter, Daniel Braun, Joachim Schofer, Ermela Yzeiraj, Volker Rudolph, Kai Friedrichs, Francesco Maisano, Maurizio Taramasso, Neil P Fam, Giovanni Bianchi, Francesco Bedogni, Paolo Denti, Ottavio Alfieri, Azeem Latib, Antonio Colombo, Christoph Hammerstingl, Robert Schueler
Background -Current surgical and medical treatment options for severe tricuspid regurgitation (TR) are limited and additional interventional approaches are required. In the present observational study, the safety and feasibility of transcatheter repair of chronic severe TR with the MitraClip system were evaluated. In addition, the effects on clinical symptoms were assessed. Methods -Patients with heart failure symptoms and severe TR on optimal medical treatment were treated with the MitraClip system. Safety, defined as periprocedural adverse events such as death, myocardial infarction, stroke, or cardiac tamponade, and feasibility, defined as successful implantation of one or more MitraClip devices and reduction of TR by at least one grade, were evaluated before discharge and after 30 days...
March 23, 2017: Circulation
https://www.readbyqxmd.com/read/28329173/mitral-valve-repair-for-secondary-mitral-regurgitation-in-non-ischaemic-dilated-cardiomyopathy-is-associated-with-left-ventricular-reverse-remodelling-and-increase-of-forward-flow
#8
Vasileios Kamperidis, Suzanne E van Wijngaarden, Philippe J van Rosendael, William Kok Fai Kong, Madelien V Regeer, Frank van der Kley, Georgios Sianos, Nina Ajmone Marsan, Jeroen J Bax, Victoria Delgado
Aims: It remains unclear whether surgical or transcatheter mitral valve repair for secondary mitral regurgitation (MR) in patients with non-ischaemic cardiomyopathy reverse the underlying left ventricular (LV) pathophysiology. We hypothesized that mitral valve repair improves LV systolic function and forward flow and induces LV reverse remodelling in this group of patients. Methods and results: Seventy-six patients (65 ± 14 years old, 43% male) with non-ischaemic cardiomyopathy and moderate to severe chronic secondary MR treated successfully with transcatheter or surgical mitral valve repair were evaluated...
February 23, 2017: European Heart Journal Cardiovascular Imaging
https://www.readbyqxmd.com/read/28326526/early-partial-clip-detachment-following-transcatheter-mitral-valve-repair
#9
Adam Rdzanek, Arkadiusz Pietrasik, Piotr Ścisło, Janusz Kochman, Grzegorz Opolski
No abstract text is available yet for this article.
2017: Kardiologia Polska
https://www.readbyqxmd.com/read/28317788/current-status-of-transcatheter-mitral-valve-therapy-in-europe-results-from-an-eapci-survey-part-ii
#10
Anna Sonia Petronio, Piera Capranzano, Emanuele Barbato, Nicolò Piazza, Andreas Baumbach, Michael Haude, Stephan Windecker
AIMS: The European Association of Percutaneous Coronary Interventions (EAPCI) assessed the current status of transcatheter valve therapy in Europe through a web-based survey. Our aim here was to report the results of that survey regarding trends in percutaneous mitral valve repair (PMVR) therapy. METHODS AND RESULTS: Among 301 European centres participating in the overall EAPCI survey, 246 (81.7%) responded to the PMVR section questions. A total of 176 (71.5%) have been undertaking a PMVR programme...
March 20, 2017: EuroIntervention
https://www.readbyqxmd.com/read/28314700/structural-heart-disease-intervention-the-canadian-landscape
#11
Anita W Asgar, Eric Horlick, Kevin McKenzie, Neil Brass, Warren J Cantor, Albert Chan, Anthony Della Siega, Jean Francois Gobeil, Saleem Kassam, Michael P Love, Samer Mansour, Giuseppe Martucci, Najaf Nadeem, Madhu K Natarajan, Vernon Paddock, Josep Rodés-Cabau, Mouhieddin Traboulsi, James L Velianou, Robert C Welsh, David Wood, John G Webb
Cardiovascular disease encompasses coronary artery disease and valvular heart disease, and the prevalence of both increases with age. Over the past decade, the landscape of interventional cardiology has evolved to encompass a new set of percutaneous procedures outside the coronary tree, including transcatheter aortic valve implantation, transcatheter mitral valve repair, and left atrial appendage occlusion. These interventions have sparked a new discipline within interventional cardiology referred to as structural heart disease (SHD) intervention...
December 13, 2016: Canadian Journal of Cardiology
https://www.readbyqxmd.com/read/28303686/afterload-mismatch-after-transcatheter-mitral-valve-repair-with-mitraclip-for-degenerative-mitral-regurgitation-in-acute-cardiogenic-shock
#12
Gilbert H L Tang, Martin Cohen, Tanya Dutta, Cenap Undemir
Acute afterload mismatch after surgery for mitral regurgitation (MR) with transient left ventricular dysfunction is well known, but not described after transcatheter mitral valve repair with MitraClip, except in functional MR and cardiomyopathy. MitraClip to manage acute severe MR and cardiogenic shock has also been rarely reported. We report here a 77-year-old female who presented with acute severe degenerative MR from a flail posterior leaflet, with cardiogenic shock requiring intra-aortic balloon pump support...
March 17, 2017: Catheterization and Cardiovascular Interventions
https://www.readbyqxmd.com/read/28286089/conventional-surgery-for-early-and-late-symptomatic-mitral-valve-stenosis-after-mitraclip-%C3%A2-intervention-an-institutional-experience-with-four-consecutive-patients
#13
Anthony Alozie, Liliya Paranskaya, Bernd Westphal, Alexander Kaminski, Gustav Steinhoff, Mohammad Sherif, Hüseyin Ince, Alper Öner
BACKGROUND: Surgical mitral valve repair is the gold standard for treatment of mitral regurgitation. Recently, the transcatheter treatment of mitral regurgitation with the MitraClip(®) device (Abbot Vascular Structural Heart, Menlo Park, CA) has demonstrated promising results in treating patients not amenable for surgical correction of mitral valve regurgitation. Most patients reported in the literature requiring surgical bailout after MitraClip treatment presented with residual or recurrent mitral valve regurgitation...
February 17, 2017: Heart, Lung & Circulation
https://www.readbyqxmd.com/read/28276754/evaluation-of-valtech-s-transcatheter-mitral-valve-repair-device
#14
REVIEW
Shingo Kuwata, Maurizio Taramasso, Andrea Guidotti, Fabian Nietlispach, Francesco Maisano
Functional mitral regurgitation is a debilitating condition, related to worsening of functional capacity and heart failure symptomatology. Cardioband (Valtech Cardio, Or Yehuda, Israel) is a novel technology designed for transcatheter repair of the mitral valve in the treatment of functional MR. Areas covered: A brief summary to direct the reader to important further reading, relevant websites; www.valtechcardio.com . An article about this device, relevant websites; www.ncbi.nlm.nih.gov/pubmed using search word 'Cardioband'...
March 2017: Expert Review of Medical Devices
https://www.readbyqxmd.com/read/28265822/systematic-review-of-model-based-economic-evaluations-of-heart-valve-implantations
#15
Simone A Huygens, Johanna J M Takkenberg, Maureen P M H Rutten-van Mölken
OBJECTIVE: To review the evidence on the cost-effectiveness of heart valve implantations generated by decision analytic models and to assess their methodological quality. METHODS: A systematic review was performed including model-based cost-effectiveness analyses of heart valve implantations. Study and model characteristics and cost-effectiveness results were extracted and the methodological quality was assessed using the Philips checklist. RESULTS: Fourteen decision-analytic models regarding the cost-effectiveness of heart valve implantations were identified...
March 6, 2017: European Journal of Health Economics: HEPAC: Health Economics in Prevention and Care
https://www.readbyqxmd.com/read/28262577/percutaneous-mitral-repair-with-mitraclip-in-patients-treated-with-transcatheter-aortic-valve-implantation
#16
Fernando Carrasco-Chinchilla, Rodrigo Estévez-Loureiro, Leire Andraka, Dabit Arzamendi, Xavier Freixa, José Suárez de Lezo
No abstract text is available yet for this article.
March 2, 2017: Revista Española de Cardiología
https://www.readbyqxmd.com/read/28216472/effects-of-atrial-fibrillation-and-heart-rate-on-percutaneous-mitral-valve-repair-with-mitraclip-results-from-the-transcatheter-mitral-valve-interventions-trami-registry
#17
Alexander Jabs, Ralph S von Bardeleben, Peter Boekstegers, Miriam Puls, Edith Lubos, Raffi Bekeredjian, Taoufik Ouarrak, Björn Plicht, Holger Eggebrecht, Georg Nickenig, Christian Butter, Rainer Hoffmann, Jochen Senges, Ulrich Hink
AIMS: In patients undergoing percutaneous edge-to-edge mitral valve repair for mitral valve regurgitation (MR), our aim was to evaluate acute and follow-up differences with pre-existing sinus rhythm (SR) or atrial fibrillation (AF), as well as comparisons stratified by baseline heart rate. METHODS AND RESULTS: Seven hundred and sixty patients who underwent a MitraClip procedure were prospectively enrolled in the TRAnscatheter Mitral valve Interventions (TRAMI) registry, and stratified according to baseline heart rhythm and heart rate with a cut-off value of 70 beats per minute...
February 20, 2017: EuroIntervention
https://www.readbyqxmd.com/read/28202256/transseptal-puncture-review-of-anatomy-techniques-complications-and-challenges
#18
REVIEW
Barry O'Brien, Haroon Zafar, Simon De Freitas, Faisal Sharif
In recent years, the transseptal puncture approach has enabled passage of increasingly large and complex devices into the left atrium. Traditional tools remain effective in creating and dilating the initial puncture, with an acceptable safety profile. Even for skilled operators, the procedure is technically demanding and requires sound understanding of atrial anatomy. Intracardiac echocardiography is useful in cases of previous septal repair, poorly defined fossa ovalis anatomy or when considering patent foramen ovale portal crossing...
April 15, 2017: International Journal of Cardiology
https://www.readbyqxmd.com/read/28185392/thrombotic-valvular-dysfunction-with-transcatheter-mitral-interventions-for-postsurgical-failures
#19
Marvin H Eng, Adam Greenbaum, Dee Dee Wang, Janet Wyman, Dnp, Heider Arjomand, Pradeep Yadav, Hassan Nemeh, Gaetano Paone, Mayra Guerrero, William O'Neill
BACKGROUND: Degenerated surgical mitral valve repairs or surgical prostheses are currently being treated with transcatheter mitral valve replacement (TMVR). We report the procedural and mid-term assessment of thirteen cases. METHODS: From 12/2013 to 12/2015, 13 consecutive patients with degenerated mitral valve repair or valve replacement were treated. Patients were assessed for mitral valve academic valve consortium (MVARC) defined outcomes. RESULTS: Immediate procedural MVARC defined technical success was 92%...
February 10, 2017: Catheterization and Cardiovascular Interventions
https://www.readbyqxmd.com/read/28145876/novel-use-of-mitraclip-for-severe-mitral-regurgitation-due-to-infective-endocarditis
#20
Pranav Chandrashekar, Erin A Fender, Mohammed A Al-Hijji, Krishnaswamy Chandrasekaran, Charanjit S Rihal, Mackram F Eleid, Nandan S Anavekar
A 75-year-old man presented with infective endocarditis. Transesophageal echocardiogram (TEE) revealed mild-moderate mitral regurgitation (MR). After 4 weeks of antibiotics, he presented with New York Heart Association class III dyspnea. Repeat TEE demonstrated severe MR. After consultation with Infectious Diseases, it was determined the infection risk was low and transcatheter mitral valve repair (TMVR) was offered. Deployment of two MitraClip devices (Abbott Vascular) resulted in symptom relief. This case demonstrates a potential role of TMVR in treating acute severe MR due to endocarditis...
February 2017: Journal of Invasive Cardiology
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