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Transcatheter mitral valve repair

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https://www.readbyqxmd.com/read/28770396/mitro-aortic-pathology-a%C3%A2-point-of-view-for-a%C3%A2-fully-transcatheter-staged-approach
#1
REVIEW
G D'Ancona, L Paranskaya, A Öner, S Kische, H Ince
Severe aortic valve stenosis (AVS) and mitral valve regurgitation (MVR) often coexist. Although a fully percutaneous treatment for the two conditions, by means of transcatheter aortic valve implantation (TAVI) followed by MitraClip, can be appealing in selected high-risk candidates, critical and strategical reasoning should be applied. In a 3-year period we have developed a single-centre experience of 14 patients who were managed with a staged percutaneous approach to treat severe AVS and MVR. The average interval from TAVI to MitraClip repair was 101 ± 12 days...
August 2, 2017: Netherlands Heart Journal
https://www.readbyqxmd.com/read/28762229/-percutaneous-edge-to-edge-mitral-valve-repair-new-transcatheter-approach-and-nursing-experience-in-patients-with-severe-mitral-regurgitation-and-prohibitive-surgical-risk
#2
Hsiu-Fen Huang, Hui-Yun Yu, Ching-Wei Lee, Hui-Chuang Chang, Mei-Ling Lin, Shin-Huey Wung
Open-heart surgery and conservative medical treatments have been the traditional, mainstay treatments for patients with severe mitral regurgitation (MR). Transcatheter edge-to-edge mitral repair is a novel technique. Using the transcatheter approach allows delivery of the clip into the left ventricle and the clipping of the orifice of the MR. The heart failure symptoms and outcomes of patients improve after this procedure. Compared to open-heart surgery, the mitral clip achieves similar MR reduction results with a significantly lower rate of complications...
August 2017: Hu Li za Zhi the Journal of Nursing
https://www.readbyqxmd.com/read/28757798/mitral-valve-replacement-current-and-future-perspectives
#3
REVIEW
Johan van der Merwe, Filip Casselman
The favorable outcomes achieved with modern mitral valve repair techniques redefined the role of mitral valve replacement. Various international databases report a significant decrease in replacement procedures performed compared with repairs, and contemporary guidelines limit the application of surgical mitral valve replacement to pathology in which durable repair is unlikely to be achieved. The progressive paradigm shift toward endoscopic and robotic mitral valve surgery is also paralleled by rapid developments in transcatheter devices, which is progressively expanding from experimental approaches to becoming clinical reality...
2017: Open Journal of Cardiovascular Surgery
https://www.readbyqxmd.com/read/28673783/combined-mitraclip-implantation-and-left-atrial-appendage-occlusion-using-the-watchman-device-a-case-series-from-a-referral-center
#4
Ana Rita G Francisco, Eduardo Infante de Oliveira, Miguel Nobre Menezes, Pedro Carrilho Ferreira, Pedro Canas da Silva, Ângelo Nobre, Fausto J Pinto
INTRODUCTION: Patients referred for percutaneous transcatheter mitral valve repair using the MitraClip(®) system frequently have atrial fibrillation, which imposes additional challenges due to the need for oral anticoagulation. Left atrial appendage occlusion is currently regarded as a non-inferior alternative to anticoagulation in patients with non-valvular atrial fibrillation and both high thromboembolic and bleeding risk. Considering that both MitraClip implantation and left atrial appendage occlusion are percutaneous techniques that require transseptal puncture, it is technically attractive to consider their concomitant use...
July 2017: Portuguese Journal of Cardiology: An Official Journal of the Portuguese Society of Cardiology
https://www.readbyqxmd.com/read/28666613/the-economics-of-transcatheter-valve-interventions
#5
REVIEW
Maneesh Sud, Derrick Y Tam, Harindra C Wijeysundera
A subset of patients who require correction of a stenotic or incompetent valve are deemed to be at excessive surgical risk, which precludes surgical repair or replacement. Transcatheter valve interventions are viable alternatives in these patients. However, these technologies are costly, and in the setting of a constrained Canadian health care budget, economic value is an important consideration to allow for fair allocation of scarce resources. Accordingly, we review the economic literature on transcatheter valve interventions, targeting a general audience...
March 25, 2017: Canadian Journal of Cardiology
https://www.readbyqxmd.com/read/28656784/the-spectrum-of-mitral-valve-pathologies-relevance-for-surgical-and-structural-interventions
#6
Sho Torii, Maria E Romero, Hiroyoshi Mori, Emanuel Harari, Frank D Kolodgie, Aloke V Finn, Renu Virmani
The mitral valve apparatus, both functionally and morphologically is composed of a constellation of individual structures, including the annulus, anterior and posterior leaflets, chordae tendineae, and papillary muscles. Most also include the left ventricular wall and the left atrium which are essential for the valve to function normally. Areas covered: The commonest conditions responsible for mitral valve dysfunction in the Western World are degenerative and functional mitral regurgitation, which are discussed in detail...
July 4, 2017: Expert Review of Cardiovascular Therapy
https://www.readbyqxmd.com/read/28645469/transcatheter-mitral-valve-repair-with-mitraclip-for-symptomatic-functional-mitral-valve-regurgitation
#7
REVIEW
Rodrigo Mendirichaga, Vikas Singh, Vanessa Blumer, Manuel Rivera, Alex P Rodriguez, Mauricio G Cohen, William W O'Neill, Sammy Elmariah
Transcatheter edge-to-edge mitral valve repair (TMVr) with MitraClip has proved to be safe and effective for high-risk surgical patients with severe symptomatic degenerative mitral regurgitation. There is paucity of data regarding its use in functional mitral regurgitation (FMR). The objective of this study was to evaluate the use of MitraClip in patients with symptomatic moderate or severe FMR and a high surgical risk. Medical libraries were systematically searched for studies assessing the use of MitraClip for patients with symptomatic moderate or severe FMR and a high surgical risk...
August 15, 2017: American Journal of Cardiology
https://www.readbyqxmd.com/read/28625371/cardiovascular-events-and-hospital-resource-utilization-pre-and-post-transcatheter-mitral-valve-repair-in-high-surgical-risk-patients
#8
MULTICENTER STUDY
Sreekanth Vemulapalli, Steven J Lippmann, Mitchell Krucoff, Adrian F Hernandez, Lesley H Curtis, Elyse Foster, Atif Qasim, Andrew Wang, Donald D Glower, Ted Feldman, Bradley G Hammill
MitraClip is an approved therapy for mitral regurgitation (MR); however, health care resource utilization pre- and post-MitraClip remains understudied. METHODS: Patients with functional and degenerative MR at high surgical risk in the EVEREST II High-Risk Registry and REALISM Continued-Access Study were linked to Medicare data. Pre- and post-MitraClip all-cause death, stroke, myocardial infarction, heart failure (HF), and bleeding hospitalizations were identified. Inpatient costs, adjusted to 2010 US dollars, were calculated, and event rate ratios and cost ratios were estimated with multivariable modeling...
July 2017: American Heart Journal
https://www.readbyqxmd.com/read/28607001/acute-mitral-regurgitation-secondary-to-papillary-muscle-tear-is-transcatheter-edge-to-edge-mitral-valve-repair-a-new-paradigm
#9
Javier A Valle, Rhonda L Miyasaka, John D Carroll
No abstract text is available yet for this article.
June 2017: Circulation. Cardiovascular Interventions
https://www.readbyqxmd.com/read/28600091/transcatheter-aortic-valve-replacement-and-mitraclip-to-reverse-heart-failure
#10
REVIEW
Sukhdeep Basra, Molly Szerlip
Valvular heart diseases such as aortic stenosis and mitral regurgitation are often associated with heart failure, which in turn increases patients' Surgical Thoracic Society (STS) score. A high STS score means the patient is high risk for surgical aortic valve replacement and mitral valve repair/replacement. Transcatheter aortic valve replacement and percutaneous mitral valve repair offer a minimally invasive alternative for the treatment of valvular heart disease in patients with severe heart failure. We aim to review the current evidence on the safety, efficacy, and outcomes of these devices in patients with severe heart failure...
July 2017: Interventional cardiology clinics
https://www.readbyqxmd.com/read/28589570/transapical-transcatheter-valve-in-ring-implantation-following-mitral-annuloplasty
#11
Steffen Pfeiffer, Laszlo Gazdag, Jürgen Jessl, Giuseppe Santarpino
Despite advances in surgical techniques for mitral valve repair, more than 20% of patients require reoperation within 10 years due to recurrence of severe mitral regurgitation. However, reoperations on the mitral valve are often associated with increased morbidity and mortality. We report a transapical mitral valve-in-ring implantation in a patient who had undergone mitral valve repair for ischemic mitral regurgitation using a complete semi-rigid Memo 3D mitral ring (LivaNova Group, Milan, Italy).
July 2017: Journal of Cardiac Surgery
https://www.readbyqxmd.com/read/28566474/mitral-valve-repair-for-degenerative-mitral-valve-disease-surgical-approach-patient-selection-and-long-term-outcomes
#12
REVIEW
Gonçalo F Coutinho, Manuel J Antunes
Mitral valve repair (MVRepair) has become the procedure of choice to correct severe degenerative mitral regurgitation (MR), due to its documented superiority to valve replacement regarding long-term survival, freedom from valve-related adverse events and preservation of left ventricular (LV) function. The refinement of MVRepair techniques has rendered almost all valves (more than 95%) amenable to repair with a 15-year freedom from reoperation of 90%. The concept of 'centres of excellence for MVRepair' has emerged, encouraging referring doctors to select the most experienced institutions or individual surgeons to deal with the most complex cases, based on repair volume, appropriate peri-procedural imaging and data regarding expected outcomes (repair, mortality and durability of repair)...
May 31, 2017: Heart: Official Journal of the British Cardiac Society
https://www.readbyqxmd.com/read/28545291/-review-on-recent-progress-of-transcatheter-mitral-valve-repair
#13
R Q Zhuge, Y J Wu
No abstract text is available yet for this article.
April 24, 2017: Zhonghua Xin Xue Guan Bing za Zhi
https://www.readbyqxmd.com/read/28532777/predictive-value-of-age-adjusted-charlson-co-morbidity-index-for-1-3-and-5-year-mortality-in-patients-requiring-transcatheter-mitral-valve-repair
#14
MULTICENTER STUDY
Mike Saji, Marc R Katz, Gorav Ailawadi, Dale E Fowler, Michael Ragosta, D Scott Lim
Co-morbidities increase markedly with aging, and they often negatively affect its prognosis. Although mortality with transcatheter mitral valve repair (TMVr) is significantly less than for open mitral valve surgery in patients at high surgical risk, it remains a concern to identify which patients will benefit from this treatment. Some prognostic metrics have been reported to guide better patient selection; however, universal risk stratification measures have not been established. This study aimed to determine if age-adjusted Charlson co-morbidity index (CCI) could predict mortality in patients who underwent TMVr and to assess its discriminatory performance in long-term outcomes...
July 15, 2017: American Journal of Cardiology
https://www.readbyqxmd.com/read/28511922/simultaneous-transseptal-para-ring-leak-closure-and-transcatheter-mitral-valve-implantation-for-the-treatment-of-surgical-mitral-repair-failure
#15
James Roy, Mehdi Eskandari, Mark Monaghan, Olaf Wendler, Jonathan Byrne, Philip MacCarthy
Repeat cardiac surgery in patients with a previous sternotomy is associated with significant morbidity and mortality. While transcatheter aortic valve implantation in high risk surgical patients is now well established, experience with transcatheter mitral valve replacement is still at an early stage. Although many successful reports of transcatheter mitral valve replacements now exist, the predominant approach has been via a transapical approach. It is likely that, as with the evolution of favoured access routes for transcatheter aortic therapies, future directions for transcatheter mitral valves will focus on smaller delivery systems favouring the transvenous transseptal approach where possible...
April 6, 2017: Heart, Lung & Circulation
https://www.readbyqxmd.com/read/28506938/dynamic-transcatheter-mitral-valve-repair-a-new-concept-to-treat-functional-mitral-regurgitation-using-an-adjustable-spacer
#16
Miriam Silaschi, Niki Nicou, Mehdi Eskandari, Omar Aldalati, Christopher Seguin, Thomas Piemonte, Theresa McDonagh, Rafal Dworakowski, Jonathan Byrne, Philip MacCarthy, Mark Monaghan, Olaf Wendler
We report about the first-in-man implantation of the Mitra-SpacerTM (Cardiosolutions Inc., West Bridgewater, MA/USA). It was implanted transapically. FMR was reduced to moderate degree. At two-months, while in NYHA II, LVEF had improved, but FMR increased and 2mL was added, reducing FMR to mild degree. Despite anticoagulation, thrombi developed around the device and the valve was replaced at eight-months. The Mitra-SpacerTM successfully bridged this patient to surgery after LVEF had recovered.
May 16, 2017: EuroIntervention
https://www.readbyqxmd.com/read/28504236/switzerland-coronary-and-structural-heart-interventions-from-2010-to-2015
#17
Fabio Rigamonti, Gregor Fahrni, Micha Maeder, Stéphane Cook, Daniel Weilenmann, Peter Wenaweser, Christian Röthlisberger, Roberto Corti, Hans Rickli, Christoph Kaiser, Marco Roffi
In 2015, Switzerland had a population of 8.3 million inhabitants. Since the first coronary angioplasty performed by Andreas Grüntzig in Zurich in 1977, the number of percutaneous procedures has steadily increased. The aim of this report is to summarise the current state of catheter-based cardiac interventions in adults in the country and to detail trends between 2010 and 2015. Since 1987, the Working Group for Interventional Cardiology of the Swiss Society of Cardiology has collected annually aggregate data from all facilities with cardiac catheterisation laboratories in the country...
May 15, 2017: EuroIntervention
https://www.readbyqxmd.com/read/28483264/transcatheter-aortic-valve-insertion-after-previous-mitral-valve-operation
#18
Kevin L Greason, Gurpreet S Sandhu, Vuyisile T Nkomo, Katherine S King, David L Joyce, Eric E Williamson, David R Holmes
OBJECTIVE: There are limited data on transcatheter aortic valve insertion after previous mitral valve operation. To better understand the associated procedural risks, we reviewed our single-center experience. METHODS: We retrospectively reviewed the records of 772 consecutive patients who received transcatheter aortic valve insertion from November 2008 through August 2016. There were 18 (2%) patients who had previous mitral valve operation that included valve repair in 4 patients (22%) and replacement in 14 (78%)...
April 4, 2017: Journal of Thoracic and Cardiovascular Surgery
https://www.readbyqxmd.com/read/28473116/elevated-mitral-valve-pressure-gradient-after-mitraclip-implantation-deteriorates-long-term-outcome-in-patients-with-severe-mitral-regurgitation-and-severe%C3%A2-heart-failure
#19
Michael Neuss, Thomas Schau, Akihiro Isotani, Markus Pilz, Maren Schöpp, Christian Butter
OBJECTIVES: This single-center study was performed to analyze the effect of an increased transvalvular gradient after the MitraClip (MC) (Abbott Laboratories, Abbott Park, Illinois) procedure on patient outcome during follow-up. BACKGROUND: Percutaneous transcatheter repair of the mitral valve with the MC device has been established as a novel technique for patients with severe mitral regurgitation and high surgical risk. This study investigated the influence of an increased pressure gradient after MC implantation on the long-term outcome of patients...
May 8, 2017: JACC. Cardiovascular Interventions
https://www.readbyqxmd.com/read/28471277/ongoing-and-future-directions-in-percutaneous-treatment-of-mitral-regurgitation
#20
REVIEW
Shingo Kuwata, Maurizio Taramasso, Andrea Guidotti, Fabian Nietlispach, Francesco Maisano
Mitral regurgitation (MR) is one of the major valvular disease. Although surgical mitral valve (MV) repair is the standard of care for patients with severe MR, an unmet need exists in the management of patients with severe symptomatic MR and high surgical risk. Transcatheter MV therapies are alternative treatment option in such patients with moderate to severe and symptomatic MR. Areas covered: Literatures to direct the reader to important further reading were searched with relevant websites; www.ncbi.nlm.nih...
June 2017: Expert Review of Cardiovascular Therapy
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