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Transcatheter mitral valve repair

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https://www.readbyqxmd.com/read/29209786/prognostic-value-of-preprocedural-6-min-walk-test-in-patients-undergoing-transcatheter-mitral-valve-repair-insights-from-the-german-transcatheter-mitral-valve-interventions-registry
#1
Jakob Ledwoch, Jennifer Franke, Edith Lubos, Peter Boekstegers, Miriam Puls, Taoufik Ouarrak, Stephan von Bardeleben, Christian Butter, Joachim Schofer, Ralf Zahn, Hüsseyin Ince, Jochen Senges, Horst Sievert
AIMS: The 6-min walk test (6 MWT) has been established as an important tool for functional assessment in heart failure patients. However, its prognostic impact on the outcome in subjects with mitral regurgitation undergoing transcatheter mitral valve repair is unknown. METHODS: This present work represents a sub-analysis of the German, prospective, multicenter, Transcatheter Mitral Valve Interventions (TRAMI) registry. Of the main study cohort (n = 828) 326 patients underwent 6 MWT prior to the procedure...
December 5, 2017: Clinical Research in Cardiology: Official Journal of the German Cardiac Society
https://www.readbyqxmd.com/read/29191615/percutaneous-mitral-valve-technology-what-s-on-the-horizon
#2
Sadip Pant, Kendra J Grubb
Mitral valve disease is common, with mitral regurgitation (MR) the most frequent pathology. The etiology of MR is diverse, but left untreated results in left ventricular (LV) volume overload, leading to remodeling, dilation of the LV, pulmonary hypertension, heart failure, and death. Mitral regurgitation is a high risk diagnosis, yet a minority of symptomatic patients are referred for discussion of surgical treatment options. Percutaneous repair options are under development to address this clinical need and emphasize correction of the underlying anatomical pathology to restore mitral valve coaptation...
November 27, 2017: Seminars in Thoracic and Cardiovascular Surgery
https://www.readbyqxmd.com/read/29171684/comparison-of-left-atrial-pressure-monitoring-with-dedicated-catheter-versus-steerable-guiding-catheter-during-transcatheter-mitral-valve-repair
#3
Mackram F Eleid, Guy S Reeder, Charanjit S Rihal
OBJECTIVE: The objective of this study was to determine the accuracy of left atrial pressure (LAP) measurement through the manufacturer provided steerable guiding catheter (SGC) during transcatheter mitral valve repair (TMVR). BACKGROUND: LAP measurement during TMVR has been shown to be associated with clinical improvement when measured through a dedicated catheter. METHODS: Simultaneous LAP was performed in consecutive patients using an independent fluid-filled 4F multipurpose catheter and compared to LAP waveforms measured through the manufacturer-provided MitraClip SGC during TMVR (Abbott, Santa Clara, CA)...
November 24, 2017: Catheterization and Cardiovascular Interventions
https://www.readbyqxmd.com/read/29160044/aortic-valve-surgery-of-the-21st-century-sutureless-avr-versus-tavi
#4
Victor S Costache, Catalina Arsenescu, Andreea Costache, Horatiu Moldovan
A new controversy is raising in cardiovascular surgery, whether or not the new generation transcatheter valves used for valve implantation are superior to surgical techniques used for traditional valve replacement. If such a debate is far from being an issue for mitral valve treatment, where minimal invasive, (robotic or video-assisted) mitral valve repair has become the gold standard for mitral valve treatment while transcatheter mitral valve solutions are lagging behind(1-4), there are many voices stating that the future of aortic valve treatment will mainly be transcatheter(5)...
November 20, 2017: Minerva Cardioangiologica
https://www.readbyqxmd.com/read/29156010/mitraclip-removal-surgical-techniques-to-preserve-native-mitral-valve-leaflets
#5
Guido Gelpi, Claudia Romagnoni, Paolo Romitelli, Riccardo Vismara
Transcatheter valve procedures are wide-spreading techniques for the treatment of heart valves pathologies. In case of implantation failure, the transcatheter device often needs to be removed. This procedure, which can alter the biological structure integrity, can limit the option available for the subsequent traditional surgery. One of the most popular devices for transcatheter mitral valve repair is the MitraClip system. In this work, we describe 2 different techniques for the surgical removal of MitraClip...
October 1, 2017: European Journal of Cardio-thoracic Surgery
https://www.readbyqxmd.com/read/29152829/procedural-trends-outcomes-and-readmission-rates-pre-and-post-fda-approval-for-mitraclip-from-the-national-readmission-database-2013-14
#6
Sidakpal S Panaich, Shilpkumar Arora, Apurva Badheka, Varun Kumar, Elad Maor, Claire Raphael, Abhishek Deshmukh, Guy Reeder, Mackram Eleid, Charanjit S Rihal
BACKGROUND: There are sparse clinical data on the procedural trends, outcomes and readmission rates following FDA approval and expansion of Transcatheter mitral valve repair/MitraClip(®) . Whether a complex new technology can be disseminated safely and quickly is controversial. METHODS: The study cohort was derived from the National Readmission Data (NRD) 2013-14. MitraClip(®) was identified using appropriate International Classification of Diseases, 9th Revision, Clinical Modification (ICD-9-CM) codes...
November 20, 2017: Catheterization and Cardiovascular Interventions
https://www.readbyqxmd.com/read/29113720/spanish-cardiac-catheterization-and-coronary-intervention-registry-26th-official-report-of-the-spanish-society-of-cardiology-working-group-on-cardiac-catheterization-and-interventional-cardiology-1990-2016
#7
Ana María Serrador Frutos, Pilar Jiménez-Quevedo, Armando Pérez de Prado, Manuel Pan Álvarez-Ossorio
INTRODUCTION AND OBJECTIVES: The Working Group on Cardiac Catheterization and Interventional Cardiology presents its annual report on the activity data for 2016. METHODS: All Spanish hospitals with catheterization laboratories were invited to voluntarily contribute their activity data. The information was collected online and was analyzed mainly by an independent company. RESULTS: In 2016, 106 centers participated in the national registry; 80 of these centers are public...
November 4, 2017: Revista Española de Cardiología
https://www.readbyqxmd.com/read/29101953/catheterization-laboratory-structural-heart-disease-devices-and-transcatheter-aortic-valve-replacement
#8
REVIEW
Paul N Fiorilli, Saif Anwaruddin, Elizabeth Zhou, Ronak Shah
The cardiac catheterization laboratory is advancing medicine by performing procedures on patients who would usually require sternotomy and cardiopulmonary bypass. These procedures are done percutaneously, allowing them to be performed on patients considered inoperable. Patients have compromised cardiovascular function or advanced age. An anesthesiologist is essential for these procedures in case of hemodynamic compromise. Interventionalists are becoming more familiar with transcatheter aortic valve replacement and the device has become smaller, both contributing to less complications...
December 2017: Anesthesiology Clinics
https://www.readbyqxmd.com/read/29096801/outcomes-with-transcatheter-mitral-valve-repair-in-the-united-states-an-sts-acc-tvt-registry-report
#9
Paul Sorajja, Sreekanth Vemulapalli, Ted Feldman, Michael Mack, David R Holmes, Amanda Stebbins, Saibal Kar, Vinod Thourani, Gorav Ailawadi
BACKGROUND: Post-market surveillance is needed to evaluate the real-world clinical effectiveness and safety of U.S. Food and Drug Administration-approved devices. OBJECTIVES: The authors examined the commercial experience with transcatheter mitral valve repair for the treatment of mitral regurgitation. METHODS: Data from the Society of Thoracic Surgery/American College of Cardiology Transcatheter Valve Therapy Registry on patients commercially treated with transcatheter mitral valve repair were analyzed...
November 7, 2017: Journal of the American College of Cardiology
https://www.readbyqxmd.com/read/29075913/role-of-echocardiography-in-transcatheter-valvular-heart-disease-interventions
#10
REVIEW
Omar K Khalique, Rebecca T Hahn
PURPOSE OF REVIEW: Transcatheter valvular interventions have increased in importance and utility for surgical valve repair and replacement. Cardiac imaging is the most crucial aspect of procedural planning and guidance. Echocardiography is a widely used, portable, and dynamic imaging modality used for many of these interventions. This review will summarize the role echocardiography in structural heart valvular interventions. RECENT FINDINGS: Intraprocedural echocardiographic guidance has been a mainstay of structural heart interventions...
October 27, 2017: Current Cardiology Reports
https://www.readbyqxmd.com/read/29074049/the-dynamic-cardiac-biosimulator-a-method-for-training-physicians-in-beating-heart-mitral-valve-repair-procedures
#11
Alberto M Leopaldi, Krzysztof Wrobel, Giovanni Speziali, Sjoerd van Tuijl, Agne Drasutiene, W Randolph Chitwood
OBJECTIVE: Previously, cardiac surgeons and cardiologists learned to operate new clinical devices for the first time in the operating room or catheterization laboratory. We describe a biosimulator that recapitulates normal heart valve physiology with associated real-time hemodynamic performance. METHODS: To highlight the advantages of this simulation platform, transventricular extruded polytetrafluoroethylene artificial chordae were attached to repair flail or prolapsing mitral valve leaflets...
September 18, 2017: Journal of Thoracic and Cardiovascular Surgery
https://www.readbyqxmd.com/read/29056395/3d-transesophageal-echocardiography-a-new-imaging-tool-for-assessment-of-mitral-regurgitation-and-for-guiding-percutaneous-edge-to-edge-mitral-valve-repair
#12
REVIEW
Francesco F Faletra, Alain Berrebi, Giovanni Pedrazzini, Laura Anna Leo, V L Paiocch, G Cautilli, Gabriele Casso, Tiziano Cassina, Tiziano Moccetti, Joseph F Malouf
Real time three dimensional transesophageal echocardiography (3D TEE) is probably the most powerful and convincing imaging method for understanding the complicated multiform morphology and for evaluating geometry, dynamics and function of degenerative and functional mitral valve (MV) regurgitation. Moreover, color Doppler 3D TEE has been valuable to identify the location of the regurgitant orifice and the severity of the mitral regurgitation. 3D TEE has been shown to be of enormous value in helping surgeons to perform MV repair...
October 19, 2017: Progress in Cardiovascular Diseases
https://www.readbyqxmd.com/read/29041893/-transcatheter-implantation-of-mitral-valve-prostheses-current-status-of-the-problem
#13
M A Karaskov, Y I Zhuravleva, V A Bogachev-Prokophiev, P D Demidov
Mitral valve disease is highly prevalent and quickly leads to development of severe heart failure. Mitral valve disease of degenerative or ischemic etiology affects 7.5 and 9.3% of population older than 65 and 75 years, respectively. "Open" (with cardiopulmonary bypass) surgical repair or valve replacement are not possible in almost half of affected patients because of their complications and concomitant diseases responsible for extremely high risk of these interventions. In the last decade, minimally invasive endovascular technology - transcatheter aortic valve implantation (TAVI) - has been widely introduced for correction of aortic valve disease in similar category of patients...
August 2017: Kardiologiia
https://www.readbyqxmd.com/read/29027633/multi-modality-imaging-in-the-evaluation-and-treatment-of-mitral-regurgitation
#14
REVIEW
Marc-André Bouchard, Claudia Côté-Laroche, Jonathan Beaudoin
Mitral regurgitation (MR) is frequent and associated with increased mortality and morbidity when severe. It may be caused by intrinsic valvular disease (primary MR) or ventricular deformation (secondary MR). Imaging has a critical role to document the severity, mechanism, and impact of MR on heart function as selected patients with MR may benefit from surgery whereas other will not. In patients planned for a surgical intervention, imaging is also important to select candidates for mitral valve (MV) repair over replacement and to predict surgical success...
October 13, 2017: Current Treatment Options in Cardiovascular Medicine
https://www.readbyqxmd.com/read/28982558/transcatheter-and-surgical-management-of%C3%A2-mitral%C3%A2-paravalvular-leak-long-term-outcomes
#15
Mohamad Alkhouli, Charanjit S Rihal, Chad J Zack, Mackram F Eleid, Elad Maor, Mohammad Sarraf, Allison K Cabalka, Guy S Reeder, Donald J Hagler, Joseph F Maalouf, Vuyisile T Nkomo, Hartzell V Schaff, Sameh M Said
OBJECTIVES: The aim of this study was to report the use trends and immediate and long-term outcomes of a large cohort of patients who underwent redo surgery or transcatheter repair of paravalvular leaks (PVLs) at a tertiary referral center. BACKGROUND: Percutaneous treatment of mitral PVL has emerged as an alternative to surgical treatment in high-risk surgical candidates. There are limited data on the utilization trends, safety, and efficacy of both procedures in the management of mitral PVL...
October 9, 2017: JACC. Cardiovascular Interventions
https://www.readbyqxmd.com/read/28969897/current-status-of-endovascular-training-for-cardiothoracic-surgery-residents-in-the-united-states
#16
COMPARATIVE STUDY
Panos N Vardas, Ada C Stefanescu Schmidt, Xiaoying Lou, Andrew B Goldstone, Gregory Pattakos, Amy G Fiedler, Elizabeth H Stephens, Vakhtang Tchantchaleishvili
BACKGROUND: Endovascular interventions for cardiovascular pathology are becoming increasingly relevant to cardiothoracic surgery. This study assessed the perceived prevalence and efficacy of endovascular skills training and identified differences among training paradigms. METHODS: Trainee responses to questions in the 2016 In-Service Training Examination survey regarding endovascular training were analyzed based on the four different cardiothoracic surgery training pathways: traditional 2- and 3-year thoracic, integrated 6-year, and combined 4+3 general and thoracic residency programs...
November 2017: Annals of Thoracic Surgery
https://www.readbyqxmd.com/read/28942384/transcatheter-mitral-valve-replacement-device-landscape-and-early-results
#17
Amisha Patel, Vinayak Bapat
Mitral regurgitation (MR) is the second most common valvular heart disease in the western world with a prevalence in the USA alone of two to four million people. MR is age-dependent and hence the MR burden is expected to increase with the increase in life expectancy observed in Europe and the USA. Medical and surgical treatment has been the cornerstone of the treatment as untreated MR results in poor prognosis. However, only a fraction of patients are offered surgical treatment due to high risk. With the success of transcatheter aortic valve implantation (TAVI), many transcatheter options have emerged to provide a less invasive option for these patients...
September 24, 2017: EuroIntervention
https://www.readbyqxmd.com/read/28931437/acute-reverse-annular-remodeling-during-mitraclip-%C3%A2-therapy-predicts-improved-clinical-outcome-in-heart-failure-patients-a-3d-echocardiography-study
#18
Theresa Herbrand, Silke Eschenhagen, Tobias Zeus, Eva Kehmeier, Katharina Hellhammer, Verena Veulemans, Malte Kelm, Jan Balzer
BACKGROUND: Transcatheter mitral valve repair (TMVR) has been shown to have acute effects on mitral valve geometry in patients with functional mitral regurgitation (FMR). This study investigates the impact of MitraClip(®) therapy-induced annular remodeling on clinical outcome and mitral regurgitation in heart failure patients. METHODS: TMVR was performed successfully in 45 patients with FMR. In this study, mitral valve datasets were obtained before and directly after MitraClip(®) implantation using three-dimensional (3D) transesophageal echocardiography, and were analyzed offline retrospectively using dedicated 3D reconstruction software...
September 20, 2017: European Journal of Medical Research
https://www.readbyqxmd.com/read/28921420/causes-of-an-increased-pressure-gradient-through-the-left-ventricular-outflow-tract-a-west-coast-experience
#19
Sayuki Kobayashi, Yoshihiko Sakai, Isao Taguchi, Hiroto Utsunomiya, Takahiro Shiota
BACKGROUND: Left ventricular outflow tract obstruction (LVOTO) occurs from not only obstructive hypertrophic cardiomyopathy but also other conditions such as sigmoid septum or post mitral valve repair. However, the changes of the LVOT pressure gradient (LVOT PG) in LVOTO with various conditions remain unclear. METHODS: The clinical characteristics and echocardiographic parameters of 73 patients with LVOT PG ≥50 mmHg at rest on Doppler ultrasound were retrospectively investigated...
September 18, 2017: Journal of Echocardiography
https://www.readbyqxmd.com/read/28890667/role-of-3d-echocardiography-in-cardiac-surgery-strengths-and-limitations
#20
REVIEW
Edwin Wilberforce Turton, Jörg Ender
PURPOSE OF REVIEW: This review aims to highlight the general and specific strengths and limitations of intraoperative 3D echocardiography. This article explains the value of real-time three-dimensional transesophageal echocardiography (RT 3D TEE) during cardiac surgery and cardiac interventions. RECENT FINDINGS: Recently published recommendations and guidelines include the use of RT 3D TEE. RT 3 D TEE provides additional value particularly for guidance during cardiac interventions (i...
2017: Current Anesthesiology Reports
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