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Transcatheter mitral valve implantation

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https://www.readbyqxmd.com/read/28187474/new-mitral-annuloplasty-ring-enables-oversizing-of-transcatheter-heart-valve-and-prevents-central-or-paravalvular-leakage
#1
Georg Daniel Duerr, Jan-Malte Sinning, Armin Georg Welz, Fritz Mellert
Background Transcatheter valve-in-ring strategies have been developed to treat recurrent mitral regurgitation (MR) after failing surgical annuloplasty. However, suboptimal THV expansion with consecutive paravalvular leakage (PVL) is a procedure-immanent issue. Methods A rigid, saddle-shaped ring was cut at four locations. The segments were reconnected with pull-springs, rearranged to the original shape, and covered with a sewing cuff. The length of the annuloplasty ring construct, including extended pull-springs, was defined by the perimeter of an appropriate THV...
February 10, 2017: Thoracic and Cardiovascular Surgeon
https://www.readbyqxmd.com/read/28186289/surgical-antegrade-transcatheter-mitral-valve-implantation-for-symptomatic-mitral-valve-disease-and-heavily-calcified-annulus
#2
Bettina Langhammer, Christoph Huber, Stephan Windecker, Thierry Carrel
No abstract text is available yet for this article.
February 1, 2017: European Journal of Cardio-thoracic Surgery
https://www.readbyqxmd.com/read/28132982/impact-of-mitral-annular-displacement-on-left-ventricular-diastolic-function-improvement-after-transcatheter-aortic-valve-implantation
#3
Hiroto Utsunomiya, Hirotsugu Mihara, Yuji Itabashi, Robert J Siegel, Tarun Chakravarty, Hasan Jilaihawi, Raj R Makkar, Takahiro Shiota
BACKGROUND: The clinical significance of left ventricular (LV) diastolic function (DF) improvement after transcatheter aortic valve implantation (TAVI) is not fully elucidated. We sought to investigate the long-term clinical and hemodynamic effects of post-TAVI DF improvement and to identify its determinants.Methods and Results:Clinical and serial echocardiographic data before and after TAVI were retrospectively reviewed together with measurement of mitral annular displacement (MAD) representing longitudinal myocardial function in 98 patients with severe aortic stenosis and ejection fraction >55%...
January 27, 2017: Circulation Journal: Official Journal of the Japanese Circulation Society
https://www.readbyqxmd.com/read/28117283/prognostic-impact-of-invasive-hemodynamic-measurements-in-combination-with-clinical-and-echocardiographic-characteristics-on-2-year-clinical-outcomes-of-patients-undergoing-transcatheter-aortic-valve-implantation
#4
Anna Franzone, Crochan J O'Sullivan, Stefan Stortecky, Dik Heg, Jonas Lanz, René Vollenbroich, Fabien Praz, Raffaele Piccolo, Masahiko Asami, Eva Roost, Lorenz Räber, Marco Valgimigli, Stephan Windecker, Thomas Pilgrim
AIMS: To evaluate the prognostic utility of right heart catheterization (RHC)-derived measures among patients undergoing transcatheter aortic valve implantation (TAVI). METHODS AND RESULTS: Data of 469 patients included in the Bern TAVI Registry between August 2007 and December 2012 and undergoing pre-operative RHC were analyzed. The relationship between hemodynamic parameters and survival was evaluated with Cox proportional hazard models. At 2-year follow-up, 118 patients had died (25...
January 25, 2017: EuroIntervention
https://www.readbyqxmd.com/read/28117279/first-percutaneous-micra-leadless-pacemaker-implantation-and-tricuspid-valve-repair-with-mitraclip-nt-for-lead-associated-severe-tricuspid-regurgitation
#5
Gilbert H L Tang, Ryan Kaple, Martin Cohen, Tanya Dutta, Cenap Undemir, Hasan Ahmad, Angelica Poniros, Joanne Bennett, Cheng Feng, Steven Lansman
AIMS: Pacemaker lead-associated severe tricuspid regurgitation (TR) can lead to right heart failure and poor prognosis. Surgery in these patients carries significant morbidities. We describe a successful treatment of symptomatic severe TR by leadless pacemaker implantation followed by tricuspid valve (TV) repair with the MitraClip NT. METHODS AND RESULTS: A 71-year-old frail female with poor functional status, chronic atrial fibrillation and permanent pacemaker implantation in 2012 presented with symptomatic moderate-severe mitral regurgitation (MR) and severe TR with the pacemaker lead as the culprit...
February 3, 2017: EuroIntervention
https://www.readbyqxmd.com/read/28112459/deep-sedation-vs-general-anesthesia-in-232-patients-undergoing-percutaneous-mitral-valve-repair-using-the-mitraclip-%C3%A2-system
#6
Patrick Horn, Katharina Hellhammer, Michael Minier, Monika A Stenzel, Verena Veulemans, Tienush Rassaf, Peter Luedike, Julia Pohl, Jan Balzer, Tobias Zeus, Malte Kelm, Ralf Westenfeld
OBJECTIVES: To investigate in a series of 232 patients whether the MitraClip(®) procedure can be performed safely using deep sedation (DS) without general anesthesia (GA). BACKGROUND: Transcatheter mitral valve repair using the MitraClip(®) system is a safe and effective therapy for severe mitral regurgitation (MR) in patients who are at high operative risk or are unsuitable for surgery. For these patients, avoidance of GA might be beneficial. METHODS: Between 2011 and 2015, we performed 232 MitraClip(®) procedures for the treatment of severe MR...
January 23, 2017: Catheterization and Cardiovascular Interventions
https://www.readbyqxmd.com/read/28108573/transcatheter-mitral-valve-implantation-a-percutaneous-transapical-system
#7
Huangdong Dai, Katharina Huenges, Saskia Pokorny, Gunther Fischer, Jochen Cremer, Anja Metzner, Derk Frank, Georg Lutter
OBJECTIVES: Despite recent achievements, implantation of a transcatheter mitral valved stent remains challenging. In this study, we present a different approach for implantation of a percutaneous mitral valved stent. METHODS: Percutaneous transapical access is combined with, respectively, a left-transatrial, right-transatrial/transseptal or transfemoral/transseptal approach for mitral valve stent implantation and secure fixation. The apical fixation and occlusion are ensured with an Amplatzer occluder...
January 19, 2017: Interactive Cardiovascular and Thoracic Surgery
https://www.readbyqxmd.com/read/28105998/simultaneous-transfemoral-aortic-and-transseptal-mitral-valve-replacement-utilising-sapien-3-valves-in-native-aortic-and-mitral-valves
#8
Mohammad Bashir, Gardar Sigurdsson, Phillip A Horwitz, Firas Zahr
AIMS: Concomitant severe calcific aortic and mitral stenosis is a relatively uncommon but very challenging valvular heart disease to manage. We sought to evaluate the feasibility of a fully percutaneous approach to replace both stenotic native mitral and aortic valves using SAPIEN 3 valves. METHODS AND RESULTS: An 87-year-old woman with chronic kidney disease stage 3, pul-monary hypertension, chronic obstructive pulmonary disease, a permanent pacemaker, and atrial fibrillation was referred with Class III heart failure symptoms...
January 20, 2017: EuroIntervention
https://www.readbyqxmd.com/read/28100340/-outcome-comparison-of-different-therapy-procedures-in-surgical-high-risk-elderly-patients-with-severe-aortic-stenosis
#9
Y Q Ye, Y T Wang, Z Li, M Y Wang, H Y Xu, W J Zhang, Q R Liu, G N Niu, Y J Wu
Objective: To compare the outcome of surgical high-risk elderly patients with severe aortic stenosis(SAS) treated by different therapy procedures, including transcatheter aortic valve implantation(TAVI), surgical aortic valve replacement(SAVR), and drug therapy. Methods: We retrospectively analyzed the clinical data of 242 surgical high-risk elderly (age ≥65 years old) SAS patients hospitalized in Fuwai Hospital between September 2012 and June 2015. According to the treatment method, patients were divided into TAVI group (81 cases), SAVR group (59 cases) and drug therapy group (102 cases)...
January 25, 2017: Zhonghua Xin Xue Guan Bing za Zhi
https://www.readbyqxmd.com/read/28099289/orthogonal-views-of-coronary-vessels-a-method-for-imaging-the-delivery-of-blood-cardioplegia-using-transesophageal-echocardiography
#10
Luiz F Maracaja Neto, Raj Modak, Robert B Schonberger
Coronary blood flow can be disrupted during cardiac interventions such as mitral valve surgeries, left atrial appendage ligation, transcatheter aortic valve implantation, and aortic procedures involving reimplantation of coronary buttons. Although difficult to accomplish, coronary imaging using transesophageal echocardiography can be performed by the use of orthogonal imaging with the ability for real-time tilt for angle adjustment. The technique described herein allows imaging of the right coronary artery, left main coronary artery bifurcation, left anterior descending, and circumflex coronary arteries...
January 17, 2017: Anesthesia and Analgesia
https://www.readbyqxmd.com/read/28096837/sutureless-aortic-valve-and-mitral-valve-repair-in-redo-cases-really-an-off-label-approach
#11
Júlia Čanádyová, Aleš Mokráček, Vojtěch Kurfirst
Sutureless aortic valve replacement (AVR) was developed as an alternative treatment option to conventional open-heart surgery and transcatheter aortic valve implantation for "gray zone" patients. The need for concurrent mitral valve surgery is generally viewed as a contraindication to sutureless AVR. The purpose of this brief paper is to report our experiences with sutureless valves in patients after previous cardiac procedures with degenerated aortic bioprostheses and concomitant mitral valve disease.
December 2016: Kardiochirurgia i Torakochirurgia Polska, Polish Journal of Cardio-Thoracic Surgery
https://www.readbyqxmd.com/read/28077510/mitral-implant-of-the-inovare-transcatheter-heart-valve-in-failed-surgical-bioprostheses-a-novel-alternative-for-valve-in-valve-procedures
#12
Diego Felipe Gaia, Ademir Massarico Braz, Matheus Simonato, Danny Dvir, João Roberto Breda, Gustavo Calado Ribeiro, Carolina Baeta Ferreira, José Augusto Marcondes Souza, Enio Buffolo, José Honório Palma
OBJECTIVES: Reoperative procedure for the treatment of a failed mitral bioprosthesis is associated with considerable risk. In some cases, mortality is high and might contraindicate the benefit of the procedure. The minimally invasive valve-in-valve (ViV) transcatheter mitral valve implant offers an alternative less-invasive approach, reducing morbidity and mortality. The objective of this paper was to evaluate the mitral ViV approach using the Braile Inovare prosthesis. METHODS: The transcatheter balloon-expandable Braile Inovare prosthesis was used in 12 cases...
January 10, 2017: Interactive Cardiovascular and Thoracic Surgery
https://www.readbyqxmd.com/read/28077468/integrated-imaging-of-echocardiography-and-computed-tomography-to-grade-mitral-regurgitation-severity-in-patients-undergoing-transcatheter-aortic-valve-implantation
#13
Philippe J van Rosendael, Suzanne E van Wijngaarden, Vasileios Kamperidis, William K F Kong, Melissa Leung, Nina Ajmone Marsan, Victoria Delgado, Jeroen J Bax
AIMS: Quantitative mitral regurgitation (MR) grading remains challenging. This study evaluated the concept of integrating echocardiography and computed tomography for grading MR severity. Specifically, an integrated parameter was developed that combines the true cross-sectional mitral regurgitant orifice area (ROA) assessed with multi-detector row computed tomography (MDCT) with flow data from echocardiography. METHODS AND RESULTS: Systolic MDCT data of 73 patients, referred for transcatheter aortic valve implantation (TAVI) who also had MR, were evaluated...
January 10, 2017: European Heart Journal
https://www.readbyqxmd.com/read/28045671/bioprosthetic-aortic-paravalvular-leak-is-valve-in-valve-another-solution
#14
Anwar Tandar, David A Bull, Frederick G P Welt
Paravalvular leak (PVL) following aortic valve implantation is a rare complication but may cause potentially serious consequences. It occurs in 2%-10% of surgical aortic valve replacements and 7%-17% of surgical mitral valve replacements. Transcatheter valve replacement data show that significant PVL occurs in 6%-8% of cases. The management of significant PVL has traditionally involved repeat surgical repair. However, many of these patients are considered too high risk to undergo a repeat surgical procedure; hence, a percutaneous transcatheter approach has often been utilized to treat these patients...
January 2017: Journal of Invasive Cardiology
https://www.readbyqxmd.com/read/28043429/results-of-cryoablation-for-atrial-fibrillation-concomitant-with-video-assisted-minimally-invasive-mitral-valve-surgery
#15
Giovanni Marchetto, Matteo Anselmino, Chiara Rovera, Samuel Mancuso, Davide Ricci, Marina Antolini, Mara Morello, Fiorenzo Gaita, Mauro Rinaldi
Interest in minimally invasive video-assisted mitral valve surgery (MIMVS) is rapidly growing. Data on concomitant atrial fibrillation (AF) ablation to MIMVS are still lacking. The present study investigates the long-term results of AF cryoablation concomitant to MIMVS. From October 2006-September 2014, 68 patients with mitral valve disease (age 65.9 ± 11.1 years, 34 men out of 68 patients, Euroscore log 5.4 ± 4.5) and drug-resistant AF underwent MIMVS via right minithoracotomy and concomitant left-sided AF endocardial cryoablation (Cryoflex Medtronic, Minneapolis, MN)...
July 2016: Seminars in Thoracic and Cardiovascular Surgery
https://www.readbyqxmd.com/read/28040318/transcatheter-mitral-valve-replacement-for-patients-with-symptomatic%C3%A2-mitral%C3%A2-regurgitation-a-global-feasibility-trial
#16
David W M Muller, Robert Saeid Farivar, Paul Jansz, Richard Bae, Darren Walters, Andrew Clarke, Paul A Grayburn, Robert C Stoler, Gry Dahle, Kjell A Rein, Marty Shaw, Gregory M Scalia, Mayra Guerrero, Paul Pearson, Samir Kapadia, Marc Gillinov, Augusto Pichard, Paul Corso, Jeffrey Popma, Michael Chuang, Philipp Blanke, Jonathon Leipsic, Paul Sorajja
BACKGROUND: Symptomatic mitral regurgitation (MR) is associated with high morbidity and mortality that can be ameliorated by surgical valve repair or replacement. Despite this, many patients with MR do not undergo surgery. Transcatheter mitral valve replacement (TMVR) may be an option for selected patients with severe MR. OBJECTIVES: This study aimed to examine the effectiveness and safety of TMVR in a cohort of patients with native valve MR who were at high risk for cardiac surgery...
January 31, 2017: Journal of the American College of Cardiology
https://www.readbyqxmd.com/read/28039339/concomitant-mitral-annular-calcification-and-severe-aortic-stenosis-prevalence-characteristics-and-outcome-following-transcatheter-aortic-valve-replacement
#17
Yigal Abramowitz, Yoshio Kazuno, Tarun Chakravarty, Hiroyuki Kawamori, Yoshio Maeno, David Anderson, Zev Allison, Geeteshwar Mangat, Wen Cheng, Ambarish Gopal, Hasan Jilaihawi, Michael J Mack, Raj R Makkar
AIMS: Calcified aortic stenosis (AS) and mitral annular calcification (MAC) have certain similar etiology and pathophysiological mechanisms. MAC is frequently encountered in pre-procedural computed tomography (CT) imaging of patients that undergo transcatheter aortic valve replacement (TAVR), but its prognostic implications for these patients have not been thoroughly investigated. This study sought to evaluate the prevalence of MAC among patients with severe AS and to assess the clinical implications of MAC on these patients during and following TAVR...
December 30, 2016: European Heart Journal
https://www.readbyqxmd.com/read/28009960/percutaneous-closure-of-massive-mitral-paravalvular-leak
#18
Tomás Benito-González, Rodrigo Estévez-Loureiro, Armando Pérez de Prado, Emilse Martínez-Paz, Carmen Garrote Coloma, Felipe Fernández-Vázquez
A 59-year-old male with a history of mitral valve replacement several years previously was admitted to the authors' institution with symptoms of advanced heart failure. Echocardiography showed a severe paravalvular dehiscence and surgery was discouraged due to high perioperative risk. A first transcatheter leak closure was unsuccessful despite the correct deployment of various occluding devices. A second percutaneous attempt was carried out with implantation of three Amplatzer Vascular Plug® III devices (five occluders were positioned in total within the oblong defect), leading to a mild residual leakage...
July 2016: Journal of Heart Valve Disease
https://www.readbyqxmd.com/read/28007276/mitral-valve-replacement-with-sapien-3-transcatheter-valve-in-severe-mitral-annular-calcification
#19
Marek Polomsky, Konstantinos P Koulogiannis, Robert M Kipperman, Barry M Cohen, Christopher J Magovern, James P Slater, Steve Xydas, Leo Marcoff, John M Brown
Transcatheter valve implantation in the mitral position with severe calcific mitral stenosis has been described in patients who are at an increased risk for conventional mitral valve surgical procedures. We report the direct deployment of the Sapien 3 valve in the mitral position with severe mitral annular calcification through a sternotomy in an arrested heart in two cases.
January 2017: Annals of Thoracic Surgery
https://www.readbyqxmd.com/read/27998844/transcatheter-implantation-of-aortic-valve-prostheses-into-degenerated-mitral-valve-bioprostheses-and-failed-annuloplasty-rings-outcomes-according-to-access-route-and-mitral-valve-academic-research-consortium-mvarc-criteria
#20
Christian Frerker, Tobias Schmidt, Michael Schlüter, Ralf Bader, Jury Schewel, Dimitry Schewel, Thomas Thielsen, Felix Kreidel, Hannes Alessandrini, Friederike Schlingloff, Ulrich Schäfer, Karl-Heinz Kuck
AIMS: The study sought to assess outcomes of transcatheter mitral valve-in-valve implantation (TMVIV) for degenerated bioprostheses and transcatheter mitral valve-in-ring implantation (TMVIR) for failed annuloplasty rings according to access route and the Mitral Valve Academic Research Consortium (MVARC) criteria. METHODS AND RESULTS: Twenty-four patients (72±13 years; eight men [33%]) underwent TMVIV (n=14) or TMVIR (n=10) for mitral regurgitation (MR; n=17) or stenosis (n=7) using balloon-expandable bioprostheses...
December 20, 2016: EuroIntervention
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