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Transcatheter mitral valve replacement

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https://www.readbyqxmd.com/read/29041893/-transcatheter-implantation-of-mitral-valve-prostheses-current-status-of-the-problem
#1
M A Karaskov, Y I Zhuravleva, V A Bogachev-Prokophiev, P D Demidov
Mitral valve disease is highly prevalent and quickly leads to development of severe heart failure. Mitral valve disease of degenerative or ischemic etiology affects 7.5 and 9.3% of population older than 65 and 75 years, respectively. "Open" (with cardiopulmonary bypass) surgical repair or valve replacement are not possible in almost half of affected patients because of their complications and concomitant diseases responsible for extremely high risk of these interventions. In the last decade, minimally invasive endovascular technology - transcatheter aortic valve implantation (TAVI) - has been widely introduced for correction of aortic valve disease in similar category of patients...
August 2017: Kardiologiia
https://www.readbyqxmd.com/read/29033384/transcatheter-mitral-valve-replacement-looking-beyond-the-implant
#2
Darren Mylotte
No abstract text is available yet for this article.
October 13, 2017: EuroIntervention
https://www.readbyqxmd.com/read/29027633/multi-modality-imaging-in-the-evaluation-and-treatment-of-mitral-regurgitation
#3
REVIEW
Marc-André Bouchard, Claudia Côté-Laroche, Jonathan Beaudoin
Mitral regurgitation (MR) is frequent and associated with increased mortality and morbidity when severe. It may be caused by intrinsic valvular disease (primary MR) or ventricular deformation (secondary MR). Imaging has a critical role to document the severity, mechanism, and impact of MR on heart function as selected patients with MR may benefit from surgery whereas other will not. In patients planned for a surgical intervention, imaging is also important to select candidates for mitral valve (MV) repair over replacement and to predict surgical success...
October 13, 2017: Current Treatment Options in Cardiovascular Medicine
https://www.readbyqxmd.com/read/29019612/unveiling-transthyretin-cardiac-amyloidosis-and-its-predictors-among-elderly-patients-with-severe-aortic-stenosis-undergoing-transcatheter-aortic-valve-replacement
#4
Adam Castaño, David L Narotsky, Nadira Hamid, Omar K Khalique, Rachelle Morgenstern, Albert DeLuca, Jonah Rubin, Codruta Chiuzan, Tamim Nazif, Torsten Vahl, Isaac George, Susheel Kodali, Martin B Leon, Rebecca Hahn, Sabahat Bokhari, Mathew S Maurer
Aims: Transthyretin cardiac amyloidosis (ATTR-CA) has been reported in patients with aortic stenosis (AS) but its prevalence and phenotype are not known. We examine elderly patients with severe symptomatic AS undergoing transcatheter aortic valve replacement (TAVR) and determine the prevalence and phenotype of ATTR-CA non-invasively. Methods and results: We performed technetium-99m pyrophosphate (99mTc-PYP) cardiac scintigraphy prospectively on patients who underwent TAVR, to screen for ATTR-CA...
October 7, 2017: European Heart Journal
https://www.readbyqxmd.com/read/28987742/systematic-review-of-transcatheter-aortic-valve-replacement-after-previous-mitral-valve-surgery
#5
John J Squiers, Srinivasa Potluri, William T Brinkman, J Michael DiMaio
No abstract text is available yet for this article.
September 14, 2017: Journal of Thoracic and Cardiovascular Surgery
https://www.readbyqxmd.com/read/28982562/prosthetic-mitral-surgical-valve-in-transcatheter-aortic-valve-replacement%C3%A2-recipients-a-multicenter-analysis
#6
Ignacio J Amat-Santos, Carlos Cortés, Luis Nombela Franco, Antonio J Muñoz-García, Jose Suárez De Lezo, Enrique Gutiérrez-Ibañes, Vicenç Serra, Mariano Larman, Raúl Moreno, Jose M De La Torre Hernandez, Rishi Puri, Pilar Jimenez-Quevedo, José M Hernández García, Juan H Alonso-Briales, Bruno García, Dae-Hyun Lee, Paol Rojas, Teresa Sevilla, Renier Goncalves, Silvio Vera, Itziar Gómez, Josep Rodés-Cabau, José A San Román
OBJECTIVES: The aim of this study was to determine the prognosis and specific complications of patients with prosthetic mitral valves (PMVs) undergoing transcatheter aortic valve replacement (TAVR). BACKGROUND: TAVR is performed relatively often in patients with PMVs, but specific risks are not well described. METHODS: A multicenter analysis was conducted, including patients with severe symptomatic aortic stenosis who underwent TAVR at 10 centers...
October 9, 2017: JACC. Cardiovascular Interventions
https://www.readbyqxmd.com/read/28982555/transseptal-transcatheter-mitral-valve-replacement-using-balloon-expandable-transcatheter-heart-valves-a-step-by-step-approach
#7
REVIEW
Marina Urena, Dominique Himbert, Eric Brochet, Jose Luis Carrasco, Bernard Iung, Patrick Nataf, Alec Vahanian
Transcatheter mitral valve replacement (TMVR) using balloon-expandable valves has become an alternative therapy for selected patients with mitral valve disease. Up to now, the transapical approach has been the preferred route, but the transseptal approach is becoming increasingly popular due to its reduced invasiveness and increased safety. However, transseptal TMVR procedures are technically challenging, and little is known about the screening process required before this therapy. The authors provide operators with a step-by-step approach from the screening process to follow-up care for transseptal TMVR procedures...
October 9, 2017: JACC. Cardiovascular Interventions
https://www.readbyqxmd.com/read/28974668/acute-severe-mitral-stenosis-immediately-after-transcatheter-aortic-valve-implantation
#8
Johann Auer, Michael Grund, Rudolf Puschmann, Robert Berent
An 86-year-old female patient was referred for treatment of symptomatic severe aortic stenosis. The heart team decided to perform transfemoral transcatheter aortic valve implantation. A 25 mm transcatheter aortic valve was implanted, but the valve migrated low into the left ventricular outflow tract. The subsequent removal and replacement procedures are described.
October 2017: Journal of Invasive Cardiology
https://www.readbyqxmd.com/read/28970276/outcomes-of-persistent-pulmonary-hypertension-following-transcatheter-aortic-valve-replacement
#9
Ahmad Masri, Islam Abdelkarim, Michael S Sharbaugh, Andrew D Althouse, Jeffrey Xu, Wei Han, Stephen Y Chan, William E Katz, Frederick W Crock, Matthew E Harinstein, Dustin E Kliner, Forozan Navid, Joon S Lee, Thomas G Gleason, John T Schindler, João L Cavalcante
OBJECTIVES: To determine the prevalence and factors associated with persistent pulmonary hypertension (PH) following transcatheter aortic valve replacement (TAVR) and its relationship with long-term mortality. METHODS: Consecutive patients who underwent TAVR from July 2011 through January 2016 were studied. The prevalence of baseline PH (mean pulmonary artery pressure ≥25 mm Hg on right heart catheterisation) and the prevalence and the predictors of persistent≥moderate PH (pulmonary artery systolic pressure (PASP)>45 mm Hg on 1 month post-TAVR transthoracic Doppler echocardiography) were collected...
September 29, 2017: Heart: Official Journal of the British Cardiac Society
https://www.readbyqxmd.com/read/28969897/current-status-of-endovascular-training-for-cardiothoracic-surgery-residents-in-the-united-states
#10
Panos N Vardas, Ada C Stefanescu Schmidt, Xiaoying Lou, Andrew B Goldstone, Gregory Pattakos, Amy G Fiedler, Elizabeth H Stephens, Vakhtang Tchantchaleishvili
BACKGROUND: Endovascular interventions for cardiovascular pathology are becoming increasingly relevant to cardiothoracic surgery. This study assessed the perceived prevalence and efficacy of endovascular skills training and identified differences among training paradigms. METHODS: Trainee responses to questions in the 2016 In-Service Training Examination survey regarding endovascular training were analyzed based on the four different cardiothoracic surgery training pathways: traditional 2- and 3-year thoracic, integrated 6-year, and combined 4+3 general and thoracic residency programs...
September 29, 2017: Annals of Thoracic Surgery
https://www.readbyqxmd.com/read/28965619/transcatheter-aortic-valve-replacement-in-patients-with-aortic-stenosis-and-mitral-regurgitation
#11
Kreton Mavromatis, Vinod H Thourani, Amanda Stebbins, Sreekanth Vemulapalli, Chandan Devireddy, Robert A Guyton, Roland Matsouaka, Nima Ghasemzadeh, Peter C Block, Bradley G Leshnower, James P Stewart, John S Rumsfeld, Stamatios Lerakis, Vasilis Babaliaros
BACKGROUND: Many patients undergoing transcatheter aortic valve replacement (TAVR) for aortic stenosis also have significant mitral regurgitation (MR). We sought to understand the association of concomitant MR with TAVR clinical outcomes, as well changes in MR following TAVR. METHODS: Patients who underwent TAVR in the US Transcatheter Valve Therapy Registry from January 3, 2012, to December 31, 2013, were studied, with longer-term clinical outcomes from Center for Medicare Services data...
September 29, 2017: Annals of Thoracic Surgery
https://www.readbyqxmd.com/read/28942390/imaging-for-structural-heart-procedures-focus-on-computed-tomography
#12
John Mooney, Stephanie L Sellers, Mickaël Ohana, João L Cavalcante, Chesnal D Arepalli, Rominder Grover, Ung Kim, Kapilan Selvakumar, Philipp Blanke, Jonathon A Leipsic
The success and continued rapid clinical integration of transcatheter valve technologies relies on imaging modalities to guide safe and effective device deployment. In particular, cardiac imaging, using both echocardiography and CT, is an integral resource for the multidisciplinary team. These modalities can provide valuable insight for the proceduralist at each stage of transcatheter-based valve insertion, as they can be used reliably to define the anatomy of interest and its relationship to surrounding structures, determine accurate device sizing, assess patients for valve-in-valve procedures, and screen for adverse features or procedural contraindications...
September 24, 2017: EuroIntervention
https://www.readbyqxmd.com/read/28942384/transcatheter-mitral-valve-replacement-device-landscape-and-early-results
#13
Amisha Patel, Vinayak Bapat
Mitral regurgitation (MR) is the second most common valvular heart disease in the western world with a prevalence in the USA alone of two to four million people. MR is age-dependent and hence the MR burden is expected to increase with the increase in life expectancy observed in Europe and the USA. Medical and surgical treatment has been the cornerstone of the treatment as untreated MR results in poor prognosis. However, only a fraction of patients are offered surgical treatment due to high risk. With the success of transcatheter aortic valve implantation (TAVI), many transcatheter options have emerged to provide a less invasive option for these patients...
September 24, 2017: EuroIntervention
https://www.readbyqxmd.com/read/28936446/transcatheter-mitral-valve-replacement-still-a-long-way-to-go
#14
EDITORIAL
Thierry Carrel
No abstract text is available yet for this article.
September 2017: Annals of Translational Medicine
https://www.readbyqxmd.com/read/28923785/transcatheter-mitral-valve-replacement-of-navigate-bioprosthesis-in-a-preclinical-model
#15
Haytham Elgharably, Jose L Navia, Cristian Baeza, Gabriel Maluenda, Samir Kapadia, Jerzy Sadowski, Krzysztof Bartuś, Cesare Beghi, Kalathi Thyagarajan, Ryan Bertwell, Rodolfo C Quijano
AIMS: To test the feasibility of trans-catheter mitral valve implantation of the NaviGate device in acute and chronic preclinical models. METHODS AND RESULTS: We evaluated the NaviGate valved stent implantation in the mitral position in an acute swine model (n=24, ≤ 5 days) through three different approaches: trans-atrial, trans-apical, and trans-septal, and in a chronic swine model (n=12, >10 days) through a trans-atrial approach. The NaviGate implantation procedures were successful in 83% of the acute model studies (n=20) and 83% of the chronic model studies (n=10)...
September 19, 2017: EuroIntervention
https://www.readbyqxmd.com/read/28917512/grabbing-the-transcatheter-valve-skirt-bail-out-technique-for-valve-embolization-during-valve-in-valve-transcatheter-mitral-valve-replacement
#16
Norihiko Kamioka, Jose Miguel Iturbe, Frank Corrigan, Stamatios Lerakis, Jessica Forcillo, Vinod Thourani, Peter Block, Vasilis Babaliaros
No abstract text is available yet for this article.
September 6, 2017: JACC. Cardiovascular Interventions
https://www.readbyqxmd.com/read/28903993/mitral-regurgitation-in-patients-with-severe-aortic-stenosis-diagnosis-and-management
#17
REVIEW
Anna Sannino, Paul A Grayburn
Severe aortic stenosis (AS) and mitral regurgitation (MR) frequently coexist. Although some observational studies have reported that moderate or severe MR is associated with higher mortality, the optimal management of such patients is still unclear. Simultaneous replacement of both aortic and mitral valves is linked to significantly higher morbidity and mortality. Recent advances in minimally invasive surgical or transcatheter therapies for MR allow for staged procedures in which surgical or transcatheter aortic valve replacement (SAVR/TAVR) is done first and MR severity re-evaluated afterwards...
September 13, 2017: Heart: Official Journal of the British Cardiac Society
https://www.readbyqxmd.com/read/28895061/valvular-heart-disease-in-women-differential-remodeling-and-response-to-new-therapies
#18
REVIEW
Jaya Chandrasekhar, George Dangas, Roxana Mehran
In the United States, valvular heart disease (VHD) has a prevalence of 2.5%, most commonly presenting as aortic stenosis (AS) or mitral valve regurgitation (MR) and increasingly observed to be of a degenerative etiology. Women frequently have latent symptoms despite significant disease, and it is therefore pertinent to consider both clinical symptoms and imaging findings for decision-making on treatment. Indeed, significant advances have been made in noninvasive imaging allowing for more accurate diagnosis and disease prognostication...
September 11, 2017: Current Treatment Options in Cardiovascular Medicine
https://www.readbyqxmd.com/read/28890667/role-of-3d-echocardiography-in-cardiac-surgery-strengths-and-limitations
#19
REVIEW
Edwin Wilberforce Turton, Jörg Ender
PURPOSE OF REVIEW: This review aims to highlight the general and specific strengths and limitations of intraoperative 3D echocardiography. This article explains the value of real-time three-dimensional transesophageal echocardiography (RT 3D TEE) during cardiac surgery and cardiac interventions. RECENT FINDINGS: Recently published recommendations and guidelines include the use of RT 3D TEE. RT 3 D TEE provides additional value particularly for guidance during cardiac interventions (i...
2017: Current Anesthesiology Reports
https://www.readbyqxmd.com/read/28879526/intracardiac-echocardiography-for-structural-heart-and-electrophysiological-interventions
#20
REVIEW
Craig Basman, Yuvrajsinh J Parmar, Itzhak Kronzon
PURPOSE OF REVIEW: With an increasing number of interventional procedures performed for structural heart disease and cardiac arrhythmias each year, echocardiographic guidance is necessary for safe and efficient results. The purpose of this review article is to overview the principles of intracardiac echocardiography (ICE) and describes the peri-interventional role of ICE in a variety of structural heart disease and electrophysiological interventions. RECENT FINDINGS: Both transthoracic (TTE) and transesophageal echocardiography have limitations...
September 6, 2017: Current Cardiology Reports
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