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Transcatheter mitral valve replacement

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https://www.readbyqxmd.com/read/28417602/novel-use-of-perfusion-balloon-inflation-to-avoid-outflow-tract-obstruction-during-transcatheter-mitral-valve-in-valve-replacement
#1
Howard C Herrmann, Wilson Y Szeto, Harold Litt, William Vernick
Left ventricular outflow tract (LVOT) obstruction is a recognized complication of transcatheter mitral valve-in-valve replacement in previous surgical prostheses. We describe a patient who was high risk for repeat open surgery in whom the LVOT was compromised by a surgical strut and the potential for LVOT obstruction. A novel approach to avoiding this complication was utilized. A perfusion balloon was inflated in the outflow tract to provide an opposing force during mitral valve deployment resulting in less flaring of the strut into the outflow tract thereby improving the neo-LVOT area...
April 18, 2017: Catheterization and Cardiovascular Interventions
https://www.readbyqxmd.com/read/28398395/-transcatheter-mitral-valve-repair-for-patients-not-amenable-to-surgical-correction-epidemiology-diagnosis-equiti-of-access-and-economic-impact
#2
Francesco Bedogni, Sergio Berti, Giovanni Esposito, Alessio Gaetano La Manna, Ugo Limbruno, Alfredo Marchese, Ciro Mauro, Alessandro Salvi, Gennaro Santoro, Giuseppe Tarantini, Fabio Tarantino, Ferdinando Varbella, Roberto Violini, Giuseppe Musumeci
Mitral regurgitation is the most common valvular heart disease in western world, with moderate to severe mitral regurgitation having a deep impact on prognosis, mortality and rehospitalizations. Advanced congestive heart failure is frequently complicated by mitral regurgitation, a pathologic condition that is often under-diagnosed. A significant proportion of patients with severe mitral regurgitation is not eligible for surgery (mitral valve repair or replacement) because of contraindications or excessive surgical risk...
February 2017: Giornale Italiano di Cardiologia
https://www.readbyqxmd.com/read/28396989/cardiac-surgery-2016-reviewed
#3
REVIEW
Torsten Doenst, Yasin Essa, Khalil Jacoub, Alexandros Moschovas, David Gonzalez-Lopez, Hristo Kirov, Mahmoud Diab, Steffen Bargenda, Gloria Faerber
For the year 2016, more than 20,000 published references can be found in Pubmed when entering the search term "cardiac surgery". Publications last year have helped to more clearly delineate the fields where classic surgery and modern interventional techniques overlap. The field of coronary bypass surgery (partially compared to percutaneous coronary intervention) was enriched by five large prospective randomized trials. The value of CABG for complex coronary disease was reconfirmed and for less complex main stem lesions, PCI was found potentially equal...
April 10, 2017: Clinical Research in Cardiology: Official Journal of the German Cardiac Society
https://www.readbyqxmd.com/read/28396198/left-ventricular-access-point-determination-for-a-coaxial-approach-to-the-mitral-annular-landing-zone-in-transcatheter-mitral-valve-replacement
#4
Philipp Blanke, Jong K Park, Paul Grayburn, Christopher Naoum, Kevin Ong, Keshav Kohli, Bjarne L Norgaard, John G Webb, Jeffrey Popma, David Boshell, Paul Sorajja, David Muller, Jonathon Leipsic
INTRODUCTION: To facilitate coaxial device deployment in transcatheter mitral valve replacement (TMVR), a coaxial approach to the mitral annular plane is needed. We sought to establish a method to determine an 'orthogonal' left ventricular (LV) access point for transapical TMVR and to quantitatively characterize its location in patients with severe mitral regurgitation using cardiac computed tomography. METHODS: Cardiac CT data sets of 54 patients with moderate-severe mitral regurgitation evaluated for potential TMVR were analyzed...
April 7, 2017: Journal of Cardiovascular Computed Tomography
https://www.readbyqxmd.com/read/28394759/combined-mitro-aortic-pathology-impact-of-previous-aortic-valve-replacement-upon-outcomes-of-mitra-clip-therapy
#5
Giuseppe D'Ancona, Stephan Kische, Jochen Senges, Taoufik Ouarrak, Miriam Puls, Raffi Bekeredjian, Horst Sievert, Erdal Safak, Jasmin Ortak, Alper Öner, Wolfgang Schillinger, Hüseyin Ince
AIMS: To identify the impact of previous aortic valve replacement (AVR) in Mitra-Clip (MC) patients. METHODS AND RESULTS: Data from the German Transcatheter Mitral Valve Interventions (TRAMI) registry were analyzed in light of previous AVR by means of either standard AVR (SAVR) or transcatheter AVR (TAVR). Out of 791 MC, 68 (8.6%) had been submitted to AVR (68.4% SAVR and 31.6% TAVR). AVR group was significantly older (77.2±8.0 years vs. 75.1±8.6 years; p<0...
April 11, 2017: EuroIntervention
https://www.readbyqxmd.com/read/28387805/transapical-transcatheter-mitral-valve-in-valve-implantation-versus-minimally-invasive-surgery-for-failed-mitral-bioprostheses%C3%A2
#6
Michele Murzi, Sergio Berti, Tommaso Gasbarri, Giuseppe Trianni, Stefano Maffei, Marco Solinas, Danny Dvir, Alfredo Giuseppe Cerillo
OBJECTIVES: The aim of this study was to compare early outcomes and survival of patients undergoing minimally invasive mitral valve replacement through a right anterior minithoracotomy (MIMVR) versus patients undergoing transcatheter transapical mitral valve-in-valve (M-VIV) implantation for a failed mitral bioprostheses. METHODS: From 2005 to 2015, 61 patients with a failed mitral bioprosthesis underwent either MIMVR ( n  = 40 patients, 65.6%) or M-VIV implantation ( n  = 21, 34...
April 6, 2017: Interactive Cardiovascular and Thoracic Surgery
https://www.readbyqxmd.com/read/28377025/diastolic-mitral-regurgitation-following-transcatheter-aortic-valve-replacement-incidence-predictors-and-association-with-clinical-outcomes
#7
Nir Flint, Zach Rozenbaum, Simon Biner, Gad Keren, Shmuel Banai, Ariel Finkelstein, Yan Topilsky, Amir Halkin
BACKGROUND: Diastolic mitral regurgitation (DMR) results from atrioventricular conduction disturbances, acute aortic regurgitation, and/or marked elevation of left ventricular filling pressure. Generally benign, in some clinical circumstances DMR has presumed to result in hemodynamic decompensation. The aforementioned causes of DMR are frequently encountered in patients treated by transcatheter aortic valve replacement (TAVR) but its clinical significance in this setting has not been studied...
April 1, 2017: Journal of Cardiology
https://www.readbyqxmd.com/read/28374279/design-analysis-and-testing-of-a-novel-mitral-valve-for-transcatheter-implantation
#8
Selim Bozkurt, Georgia L Preston-Maher, Ryo Torii, Gaetano Burriesci
Mitral regurgitation is a common mitral valve dysfunction which may lead to heart failure. Because of the rapid aging of the population, conventional surgical repair and replacement of the pathological valve are often unsuitable for about half of symptomatic patients, who are judged high-risk. Transcatheter valve implantation could represent an effective solution. However, currently available aortic valve devices are inapt for the mitral position. This paper presents the design, development and hydrodynamic assessment of a novel bi-leaflet mitral valve suitable for transcatheter implantation...
April 3, 2017: Annals of Biomedical Engineering
https://www.readbyqxmd.com/read/28374178/current-status-of-catheter-based-treatment-of-mitral-valve-regurgitation
#9
REVIEW
Mario Gössl, Robert S Farivar, Richard Bae, Paul Sorajja
PURPOSE OF REVIEW: This review examines the current status of catheter-based repair and replacement for mitral valve disease, with a focus on native primary and secondary mitral valve regurgitation. RECENT FINDINGS: Transcatheter mitral valve repair with the MitraClip®, with >40,000 performed procedures worldwide, has significantly advanced the field of transcatheter therapy for mitral valve regurgitation. Transcatheter mitral valve replacement remains in the early stages of development, mainly due to the complex anatomy and physiology of the mitral valve...
May 2017: Current Cardiology Reports
https://www.readbyqxmd.com/read/28373791/transcatheter-coil-embolization-of-iatrogenic-coronary-artery-left-ventricle-fistula-after-mitral-valve-replacement
#10
Ata Firuzi, Mohammad Javad Alemzadeh-Ansari, Hamid Reza Pouraliakbar
Acquired causes of coronary fistulas are rare disorders and may develop following coronary atherosclerosis, infection, or trauma (iatrogenic). Iatrogenic coronary fistulas may be acquired secondary to surgical or nonsurgical interventions. We describe a case of an iatrogenic coronary artery-left ventricle fistula following mitral valve replacement surgery, presented with ventricular arrhythmia and heart failure. In a unique technique, we implanted three coils with the aid of a Scepter C balloon with inflation at the ostial portion of the left circumflex artery...
April 2017: Journal of the Saudi Heart Association
https://www.readbyqxmd.com/read/28364394/transcatheter-mitral-valve-interventions-current-therapies-and-future-directions
#11
REVIEW
Ramon A Partida, Sammy Elmariah
Transcatheter interventions for the treatment of aortic valve stenosis have become commonplace since the advent of transcatheter aortic valve implantation. However, transcatheter mitral valve therapies have lagged in development due to the complexity of mitral valve anatomy. Transcatheter edge-to-edge leaflet repair using the MitraClip device provides an option for the treatment of severe primary mitral valve regurgitation in high or prohibitive surgical risk patients, and multiple novel approaches are evolving to replace or repair the mitral valve...
May 2017: Current Treatment Options in Cardiovascular Medicine
https://www.readbyqxmd.com/read/28345211/3d-echocardiographic-analysis-of-aortic-annulus-for-transcatheter-aortic-valve-replacement-using-novel-aortic-valve-quantification-software-comparison-with-computed-tomography
#12
Anuj Mediratta, Karima Addetia, Diego Medvedofsky, Robert J Schneider, Eric Kruse, Atman P Shah, Sandeep Nathan, Jonathan D Paul, John E Blair, Takeyoshi Ota, Husam H Balkhy, Amit R Patel, Victor Mor-Avi, Roberto M Lang
BACKGROUND: With the increasing use of transcatheter aortic valve replacement (TAVR) in patients with aortic stenosis (AS), computed tomography (CT) remains the standard for annulus sizing. However, 3D transesophageal echocardiography (TEE) has been an alternative in patients with contraindications to CT. We sought to (1) test the feasibility, accuracy, and reproducibility of prototype 3DTEE analysis software (Philips) for aortic annular measurements and (2) compare the new approach to the existing echocardiographic techniques...
March 27, 2017: Echocardiography
https://www.readbyqxmd.com/read/28336789/percutaneous-therapy-for-tricuspid-regurgitation-a-new-frontier-for-interventional-cardiology
#13
Samir R Kapadia, Amar Krishnaswamy, E Murat Tuzcu
Functional tricuspid regurgitation (FTR) is common, whether in association with mitral or aortic valve disease or presenting as an isolated valvular disease. Several studies have shown that TR is associated with poor patient outcomes, though a cause-and-effect relationship of TR to mortality has not been proven. Similarly the impact of surgical treatment of TR on outcomes needs well-controlled randomized trials that are under planning. The current professional society guidelines for treatment of TR are based on expert opinions with a level of evidence C for all indications...
March 23, 2017: Circulation
https://www.readbyqxmd.com/read/28314622/diastolic-function-and-transcatheter-aortic-valve-replacement
#14
John E A Blair, Prashant Atri, Julie L Friedman, James D Thomas, Kent Brummel, Ranya N Sweis, Issam Mikati, S Chris Malaisrie, Charles J Davidson, James D Flaherty
BACKGROUND: Little is known about baseline diastolic dysfunction and changes in diastolic dysfunction grade after transcatheter aortic valve replacement (TAVR) for aortic stenosis (AS) and its impact on overall outcomes. The aim of this study was to describe baseline diastolic dysfunction and changes in diastolic dysfunction grade that occur with TAVR and their relationship to mortality and rehospitalization. METHODS: This was a single-center study evaluating all TAVRs from January 2012 to June 2014...
March 14, 2017: Journal of the American Society of Echocardiography
https://www.readbyqxmd.com/read/28295972/first-report-of-a-simultaneous-transcatheter-mitral-valve-in-valve-and-aortic-valve-replacement-in-a-left-ventricular-assist-device-patient
#15
Christopher Meduri, James Kauten, Mani Vannan, Vivek Rajagopal
Transcatheter aortic valve replacement is standard of care for patients with severe aortic stenosis at high risk for surgical aortic valve replacement. Although not intended for treatment of primary aortic insufficiency, several transcatheter aortic valve prostheses have been used to treat patients with severe aortic insufficiency (AI), including patients with left ventricular assist devices (LVAD), in whom significant AI is not uncommon. Similarly, transcatheter valve replacements have been used for valve-in-valve treatment, in the pulmonary, aortic, and mitral positions, either via a retrograde femoral approach or antegrade transseptal approach (mitral valve-in-valve)...
March 15, 2017: Catheterization and Cardiovascular Interventions
https://www.readbyqxmd.com/read/28286089/conventional-surgery-for-early-and-late-symptomatic-mitral-valve-stenosis-after-mitraclip-%C3%A2-intervention-an-institutional-experience-with-four-consecutive-patients
#16
Anthony Alozie, Liliya Paranskaya, Bernd Westphal, Alexander Kaminski, Gustav Steinhoff, Mohammad Sherif, Hüseyin Ince, Alper Öner
BACKGROUND: Surgical mitral valve repair is the gold standard for treatment of mitral regurgitation. Recently, the transcatheter treatment of mitral regurgitation with the MitraClip(®) device (Abbot Vascular Structural Heart, Menlo Park, CA) has demonstrated promising results in treating patients not amenable for surgical correction of mitral valve regurgitation. Most patients reported in the literature requiring surgical bailout after MitraClip treatment presented with residual or recurrent mitral valve regurgitation...
February 17, 2017: Heart, Lung & Circulation
https://www.readbyqxmd.com/read/28281857/engineering-challenges-and-the-future-prospects-of-transcatheter-mitral-valve-replacement-technologies-a-comprehensive-review-of-case-studies
#17
Ranjitha Rebecca Jeevan, Bhaskar Mohan Murari
Catheter based Interventional procedures have become an indispensable treatment option for patients contraindicated for surgical heart valve replacement . The broad spectrum of disease that affect the mitral valve have increased the need for a transcatheter mitral valve replacement (TMVR) device. As complex as the mitral valve anatomy is, so are challenges in the development of a TMVR device. Areas covered: This review article analyses the challenges in the development of the TMVR device from an engineering perspective of material and device design...
April 2017: Expert Review of Medical Devices
https://www.readbyqxmd.com/read/28266162/short-term-results-of-alcohol-septal-ablation-as-a-bail-out-strategy-to-treat-severe-left-ventricular-outflow-tract-obstruction-after-transcatheter-mitral-valve-replacement-in-patients-with-severe-mitral-annular-calcification
#18
Mayra Guerrero, Dee Dee Wang, Dominique Himbert, Marina Urena, Amit Pursnani, Georges Kaddissi, Vijay Iyer, Michael Salinger, Tarun Chakravarty, Adam Greenbaum, Raj Makkar, Alec Vahanian, Ted Feldman, William O'Neill
OBJECTIVES: To evaluate the outcomes of the early experience of percutaneous alcohol septal ablation in patients with severe left ventricular outflow tract (LVOT) obstruction post transcatheter mitral valve replacement (TMVR). BACKGROUND: Severe LVOT obstruction with hemodynamic compromise is a complication of TMVR associated with high mortality. Percutaneous alcohol septal ablation has recently been described as a therapeutic option in this setting. METHODS: Multicenter retrospective review of clinical outcomes of patients undergoing alcohol septal ablation to treat LVOT obstruction after TMVR for severe mitral stenosis with severe mitral annular calcification...
March 7, 2017: Catheterization and Cardiovascular Interventions
https://www.readbyqxmd.com/read/28265822/systematic-review-of-model-based-economic-evaluations-of-heart-valve-implantations
#19
Simone A Huygens, Johanna J M Takkenberg, Maureen P M H Rutten-van Mölken
OBJECTIVE: To review the evidence on the cost-effectiveness of heart valve implantations generated by decision analytic models and to assess their methodological quality. METHODS: A systematic review was performed including model-based cost-effectiveness analyses of heart valve implantations. Study and model characteristics and cost-effectiveness results were extracted and the methodological quality was assessed using the Philips checklist. RESULTS: Fourteen decision-analytic models regarding the cost-effectiveness of heart valve implantations were identified...
March 6, 2017: European Journal of Health Economics: HEPAC: Health Economics in Prevention and Care
https://www.readbyqxmd.com/read/28240641/transcatheter-mitral-valve-replacement-with-a-novel-self-expandable-prosthesis-single-institutional-experience-procedural-outcomes-and-follow-up
#20
Gian Paolo Ussia, Valeria Cammalleri, Jawahar L Mehta, Kunal Sarkar, Saverio Muscoli, Pasquale de Vico, Giovanni Ruvolo, Francesco Romeo
AIMS: We report our experience with the CardiAQ prosthetic valve using both transapical and transseptal access. Aim of our study was proving the feasibility, safety and effectiveness of a novel transcatheter mitral valve bioprosthesis. METHODS: Four patients with severe mitral regurgitation, not eligible for mitral valve surgery, were treated with the CardiAQ valve. The procedures were performed under general anaesthesia, fluoroscopic and transesophageal echocardiographic guidance...
February 24, 2017: Journal of Cardiovascular Medicine
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