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Endocrinology & Diabetes

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https://www.readbyqxmd.com/read/28725272/brazilian-guidelines-on-prevention-of-cardiovascular-disease-in-patients-with-diabetes-a-position-statement-from-the-brazilian-diabetes-society-sbd-the-brazilian-cardiology-society-sbc-and-the-brazilian-endocrinology-and-metabolism-society-sbem
#1
REVIEW
Marcello Casaccia Bertoluci, Rodrigo Oliveira Moreira, André Faludi, Maria Cristina Izar, Beatriz D Schaan, Cynthia Melissa Valerio, Marcelo Chiara Bertolami, Ana Paula Chacra, Marcus Vinicius Bolivar Malachias, Sérgio Vencio, José Francisco Kerr Saraiva, Roberto Betti, Luiz Turatti, Francisco Antonio Helfenstein Fonseca, Henrique Tria Bianco, Marta Sulzbach, Adriana Bertolami, João Eduardo Nunes Salles, Alexandre Hohl, Fábio Trujilho, Eduardo Gomes Lima, Marcio Hiroshi Miname, Maria Teresa Zanella, Rodrigo Lamounier, João Roberto Sá, Celso Amodeo, Antonio Carlos Pires, Raul D Santos
BACKGROUND: Since the first position statement on diabetes and cardiovascular prevention published in 2014 by the Brazilian Diabetes Society, the current view on primary and secondary prevention in diabetes has evolved as a result of new approaches on cardiovascular risk stratification, new cholesterol lowering drugs, and new anti-hyperglycemic drugs. Importantly, a pattern of risk heterogeneity has emerged, showing that not all diabetic patients are at high or very high risk. In fact, most younger patients who have no overt cardiovascular risk factors may be more adequately classified as being at intermediate or even low cardiovascular risk...
2017: Diabetology & Metabolic Syndrome
https://www.readbyqxmd.com/read/28724173/a-comparative-study-between-myo-inositol-and-metformin-in-the-treatment-of-insulin-resistant-women
#2
K Nas, L Tűű
OBJECTIVE: Insulin resistance (IR) is a common disorder, which can impair female fertility and is characterized by phenotypic heterogeneity. Life-style treatment and insulin sensitizers are commonly used in the management of women with IR and consequent hyperinsulinemia, in order to restore the normal endocrinological and clinical parameters. Metformin (MET) is considered one of the first approaches to this pathology but new evidences are showing promising results using myo-inositol (MYO) in the management of this pathology...
June 2017: European Review for Medical and Pharmacological Sciences
https://www.readbyqxmd.com/read/28721140/serum-adipokines-and-vitamin-d-levels-in-patients-with-type-1-diabetes-mellitus
#3
Mohamed M Ismail, Tamer A Abdel Hamid, Alshaymaa A Ibrahim, Huda Marzouk
INTRODUCTION: Adiponectin, leptin and resistin are adipokines that play important roles in the regulation of lipid and carbohydrate metabolism in type 2 diabetes (T2DM). However, their influence in type 1 diabetes mellitus is still unknown. The aim of this study was to measure serum adiponectin, leptin and resistin levels and to investigate their relationships with vitamin D and other clinical and laboratory parameters in patients with type 1 diabetes. MATERIAL AND METHODS: Fifty subjects with type 1 diabetes and 50 healthy age- and sex-matched subjects were selected from the Endocrinology Outpatient Clinic of Cairo University Pediatrics Hospital...
June 2017: Archives of Medical Science: AMS
https://www.readbyqxmd.com/read/28719837/prescription-trends-and-the-selection-of-initial-oral-antidiabetic-agents-for-patients-with-newly-diagnosed-type-2-diabetes-a-nationwide-study
#4
C-H Liu, S-T Chen, C-H Chang, L-M Chuang, M-S Lai
OBJECTIVES: The aim of this study was to examine the characteristics of patients, physicians, and medical facilities, and their association with prescriptions that do not include metformin as the initial oral antidiabetic agent. STUDY DESIGN: Observational, cross-sectional study. METHODS: Patients with incident type 2 diabetes between January 1, 2006, and December 31, 2010, were identified from the Taiwan National Insurance Research Database...
July 15, 2017: Public Health
https://www.readbyqxmd.com/read/28718236/dose-comparison-and-side-effect-profile-of-metformin-extended-release-versus-metformin-immediate-release
#5
Maliha Hameed, Khurshid Khan, Sadia Salman, Nasir Mehmood
BACKGROUND: Diabetes Mellitus type 2 is very common worldwide, with majority of cases in Asia Pacific region. Metformin is the first line therapy, along with lifestyle modification for all type 2 diabetics as recommended by ADA. Metformin is available as conventional Metformin Immediate Release (MIR) and Metformin Extended Release (MXR). Metformin XR has better gastrointestinal tolerability and fewer side effects as compared to Metformin IR, with similar efficacy regarding anti-hyperglycaemic effects...
April 2017: Journal of Ayub Medical College, Abbottabad: JAMC
https://www.readbyqxmd.com/read/28712186/glycaemic-control-of-type-2-diabetic-patients-during-ramazan-fasting
#6
Uzma Malik, Nasir Mahmood, Khurshid Ahmed Khan, Maliha Hameed, Fawad Ahmed Randhawa, Sadia Salman, Amna Riaz, Khadija Waheed, Aqeela Rasheed
BACKGROUND: Among five main pillars of Islam Fasting is one of the key elements, all healthy adult Muslims have to observe fast from dawn till dusk during the holy month of Ramadan. According to a 2009 demographic study, Islam has 1.57 billion believers, making up 23% of the world population of 6.8 billion, and is growing by 3% per year. EPIDIAR (epidemiology of diabetes and Ramadan) study showed that 43% patients with type 1 and 79% patients with type2 diabetes observe fast during the month of Ramadan...
January 2017: Journal of Ayub Medical College, Abbottabad: JAMC
https://www.readbyqxmd.com/read/28690897/a-case-of-multiple-myeloma-presenting-with-diabetes-insipidus
#7
Rudrajit Paul, Aditya V Ruia, Asim Saha, Jayati Mondal, T J Sau, Indranil Thakur, Kunal Haldar
Multiple myeloma (MM) can present with involvement of the central nervous system in the form of nerve palsy, plasma cell masses or, rarely, with endocrinological effects due to involvement of the pituitary gland. Usually, in such cases, the disease has a rapid progression and poor prognosis. We report a 52-year-old man who was admitted to the Kolkata Medical College, Kolkata, India, in 2016 with a prolonged low-grade fever and hypernatremia. Shortly afterwards, the patient began to complain of increased urinary frequency and drowsiness...
May 2017: Sultan Qaboos University Medical Journal
https://www.readbyqxmd.com/read/28689519/insulin-resistance-and-glucose-levels-in-subjects-with-subclinical-hypothyroidism
#8
Sikandar Hayat Khan, Nadeem Fazal, Aamir Ijaz, Syed Mohsin Manzoor, Naveed Asif, Tariq Rafi, Muhammad Yasir, Najmusaquib Khan Niazi
OBJECTIVE: To compare insulin resistance and glycemic indicators among subjects with euthyroidism and subclinical hypothyroidism. STUDY DESIGN: Comparative cross-sectional study. PLACE AND DURATION OF STUDY: Department of Pathology and Medicine, PNS Hafeez, Islamabad, in collaboration with the Department of Chemical Pathology and Endocrinology at the Armed Forces Institute of Pathology (AFIP), Rawalpindi, from December 2015 to September 2016...
June 2017: Journal of the College of Physicians and Surgeons—Pakistan: JCPSP
https://www.readbyqxmd.com/read/28687199/leveraging-syntax-to-better-capture-the-semantics-of-elliptical-coordinated-compound-noun-phrases
#9
Catherine Blake, Tom Rindflesch
Full-text scientific articles are increasingly available, but capturing the meaning conveyed within an article automatically remains a bottleneck for semantic search and reasoning systems. In this paper we consider elliptical coordinated compound noun phrases that authors use to save space in an article. Systems that do not attend to coordination would incorrectly interpret "breast or lung cancer" as a body part (breast) and a disease (lung cancer) rather than two diseases. The algorithmic approach introduced in this paper uses a generate-and-test strategy where candidate expansions for forward, backward and complex ellipses are generated from syntactic dependencies...
July 4, 2017: Journal of Biomedical Informatics
https://www.readbyqxmd.com/read/28680865/diabetes-self-management-education-experience-of-people-with-diabetes
#10
Leila Mardanian Dehkordi, Samereh Abdoli
Introduction: Diabetes self-management education (DSME) is a major factor which can affects quality of life of people with diabetes (PWD). Understanding the experience of PWD participating in DSME programs is an undeniable necessity in providing effective DSME to this population. The Aim of the study was to explore the experiences of PWD from a local DSME program in Iran. Methods: This study applied a descriptive phenomenological approach. The participants were PWD attending a well-established local DSME program in an endocrinology and diabetes center in Isfahan, Iran...
June 2017: Journal of Caring Sciences
https://www.readbyqxmd.com/read/28680863/adherence-to-insulin-self-administration-and-associated-factors-among-diabetes-mellitus-patients-at-tikur-anbessa-specialized-hospital
#11
Yusuf Gerada, Zuriyash Mengistu, Asrat Demessie, Atsede Fantahun, Kahsu Gebrekirstos
BACKGROUND: The goals of diabetes treatment are to keep blood glucose levels as near normal as possible while avoiding complications. Despite the benefits of insulin therapy, many people with diabetes don't adhere to treatment. Some avoid insulin therapy or refuse to start it. Several studies investigating adherence to chronic disease treatment have evidenced that patients often discontinue their medications or even do not take them at all because they consider them ineffective or experience untoward side effects...
2017: Journal of Diabetes and Metabolic Disorders
https://www.readbyqxmd.com/read/28677414/self-reported-compensation-techniques-for-carbohydrate-exercise-and-alcohol-behaviors-in-patients-with-type-1-diabetes-on-insulin-pump-therapy
#12
Danielle Groat, Hiral Soni, Maria Adela Grando, Bithika Thompson, Curtiss B Cook
Studies have found variability in self-care behaviors in patients with type 1 diabetes, particularly when incorporating exercise and alcohol consumption. The objective of this study was to provide results from a survey to understand (1) insulin pump behaviors, (2) reported self-management behaviors for exercise and alcohol, and (3) perceptions of the effects of exercise and alcohol on blood glucose (BG) control. Fourteen participants from an outpatient endocrinology practice were recruited and administered an electronic survey...
July 1, 2017: Journal of Diabetes Science and Technology
https://www.readbyqxmd.com/read/28675669/a-two-year-audit-of-outcomes-of-pituitary-surgery-at-an-australian-teaching-hospital
#13
Timothy M E Davis, Imran Badshah, Jocelyn Drinkwater, Emily Kusich, Erin Latkovic, Neville Knuckey
BACKGROUND: There is evidence that cure rates and complications are influenced by the case load in neurosurgical centres performing transsphenoidal pituitary surgery. Although Australian centres may perform relatively small numbers of these procedures, there have been few published audits of their performance. AIMS: To conduct an audit of surgery for pituitary tumours between 2012 and 2014 in the only public hospital neurosurgical unit in the state of Western Australia...
July 4, 2017: Internal Medicine Journal
https://www.readbyqxmd.com/read/28670540/effect-of-vitamin-d-supplementation-on-vascular-functions-and-oxidative-stress-in-type-2-diabetic-patients-with-vitamin-d-deficiency
#14
Nishanthi Anandabaskar, Sandhiya Selvarajan, Steven Aibor Dkhar, Sadish Kumar Kamalanathan, Kadhiravan Tamilarasu, Zachariah Bobby
BACKGROUND: Vitamin D levels are reported to have an inverse liaison with the risk of cardiovascular diseases. Hence, we aimed to evaluate the effect of Vitamin D supplementation on changes in vascular functions and oxidative stress in type 2 diabetic patients with Vitamin D deficiency. SUBJECTS AND METHODS: One hundred and three patients with type 2 diabetes attending endocrinology outpatients department in a tertiary care hospital were screened for Vitamin D deficiency...
July 2017: Indian Journal of Endocrinology and Metabolism
https://www.readbyqxmd.com/read/28650348/an-update-on-type-2-diabetes-management-in-primary-care
#15
Jeffrey Waddell
Diabetes mellitus is a chronic disease impacting glucose metabolism. Type 2 diabetes mellitus (T2DM) stems from the inability of the body to utilize endogenous insulin properly. Approximately 90% to 95% of newly diagnosed cases of diabetes are T2DM. This article focuses on the initial treatment of T2DM based on the 2017 American Association of Clinical Endocrinologists and the American College of Endocrinology clinical practice guidelines. The 2017 update includes changes and additions regarding psychosocial management, physical activity, surgery, and hypoglycemia...
June 22, 2017: Nurse Practitioner
https://www.readbyqxmd.com/read/28648011/-relationship-between-carotid-plaque-and-diabetic-retinopathy-in-type-2-diabetes-mellitus-patients
#16
Y Y Xiao, M K Yuan, P Xi, B Gao
Objective: To analyze the relevant factors for diabetic retinopathy. Methods: The data of type 2 diabetes mellitus patients undergoing general examination and ophthalmology specialist consultation were collected from the inpatients of Department of Endocrinology in Beijing Airport Hospital between 2013 and 2016, and the relevant factors of diabetic retinopathy were retrospectively analyzed. Results: A total of 432 cases were analyzed, including 168 cases of non-diabetic retinopathy and 264 cases of diabetic retinopathy...
June 27, 2017: Zhonghua Yi Xue za Zhi [Chinese medical journal]
https://www.readbyqxmd.com/read/28645354/-acromegaly-and-cushing-s-disease-persistence-of-comorbidities-after-the-control-of-hypersecretion
#17
C Rochette, F Castinetti, T Brue
Acromegaly and Cushing's disease lead to common and distinct comorbidities. Currently available treatments lead to the control of hyper secretion in the majority of cases. However, the prevalence of the comorbidities does not always go back to the one of the normal population after remission. For instance, about 1/3 of acromegalic patients with diabetes and half of patients with Cushing's disease and diabetes will have normal blood glucose values after remission. In contrast, high blood pressure frequently recovers after remission in both diseases...
October 2016: Annales D'endocrinologie
https://www.readbyqxmd.com/read/28639064/whole-lipid-profile-and-not-only-hdl-cholesterol-is-impaired-in-children-with-coexisting-type-1-diabetes-and-untreated-celiac-disease
#18
Silvana Salardi, Giulio Maltoni, Stefano Zucchini, Dario Iafusco, Angela Zanfardino, Santino Confetto, Sonia Toni, Maximiliano Zioutas, Marco Marigliano, Vittoria Cauvin, Roberto Franceschi, Ivana Rabbone, Barbara Predieri, Riccardo Schiaffini, Alessandro Salvatoni
AIMS: Low HDL cholesterol (HDL-C) levels have been described in patients with coexisting type 1 diabetes mellitus (T1DM) and celiac disease (CD). Data on other possible lipid abnormalities that could further increase cardiovascular risk in these patients are scarce and incomplete. Aim of this retrospective multicenter study was to evaluate whole lipid profiles, besides HDL-C, in children with T1DM associated with biopsy-proven CD, and to investigate the influence of age and degree of adherence to gluten-free diet (GFD) on lipid changes...
June 21, 2017: Acta Diabetologica
https://www.readbyqxmd.com/read/28637825/we-know-more-than-we-can-tell-about-diabetes-and-vascular-disease-the-2016-edwin-bierman-award-lecture
#19
Clay F Semenkovich
The Edwin Bierman Award Lecture is presented in honor of the memory of Edwin L. Bierman, MD, an exemplary scientist, mentor, and leader in the field of diabetes, obesity, hyperlipidemia, and atherosclerosis. The award and lecture recognizes a leading scientist in the field of macrovascular complications and contributing risk factors in diabetes. Clay F. Semenkovich, MD, the Irene E. and Michael M. Karl Professor and Chief of the Division of Endocrinology, Metabolism and Lipid Research at Washington University School of Medicine in St...
July 2017: Diabetes
https://www.readbyqxmd.com/read/28625907/long-standing-isolated-autoimmune-hypothalamitis-diagnosed-with-endoscopic-transventricular-biopsy-a-case-report
#20
Lorenzo Bertulli, Giulio Andrea Bertani, Umberto Gianelli, Giovanna Mantovani, Paolo Maria Rampini, Marco Locatelli
BACKGROUND: Autoimmune hypothalamitis, which is among the causes of acquired central diabetes insipidus, has been described very rarely in the literature. This condition is probably provoked by the production of anti-vasopressin secreting cells antibodies and anti-hypothalamus antibodies, and is often associated with pituitary or polyendocrine autoimmunity. Correct diagnosis and immediate treatment are essential in order to avoid the progression of the pathological process. CASE DESCRIPTION: A woman diagnosed with central diabetes insipidus 12 year ago, suffering from panhypopituitarism and mild memory deficit came to our attention...
June 15, 2017: World Neurosurgery
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