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Endocrinology & Diabetes

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https://www.readbyqxmd.com/read/28625907/long-standing-isolated-autoimmune-hypothalamitis-diagnosed-with-endoscopic-transventricular-biopsy-a-case-report
#1
Lorenzo Bertulli, Giulio Andrea Bertani, Umberto Gianelli, Giovanna Mantovani, Paolo Maria Rampini, Marco Locatelli
BACKGROUND: Autoimmune hypothalamitis, which is among the causes of acquired central diabetes insipidus, has been described very rarely in the literature. This condition is probably provoked by the production of anti-vasopressin secreting cells antibodies and anti-hypothalamus antibodies, and is often associated with pituitary or polyendocrine autoimmunity. Correct diagnosis and immediate treatment are essential in order to avoid the progression of the pathological process. CASE DESCRIPTION: A woman diagnosed with central diabetes insipidus 12 year ago, suffering from panhypopituitarism and mild memory deficit came to our attention...
June 15, 2017: World Neurosurgery
https://www.readbyqxmd.com/read/28617043/eveningness-is-associated-with-greater-depressive-symptoms-in-type-2-diabetes-patients-a-study-in-two-different-ethnic-cohorts
#2
Sunee Saetung, Hataikarn Nimitphong, Nantaporn Siwasaranond, Areesa Manodpitipong, Stephanie J Crowley, Megan M Hood, Sirimon Reutrakul
BACKGROUND: Eveningness is associated with greater depressive symptoms in the general population. Depression and type 2 diabetes (T2D) commonly coexist. We aimed to explore the association between morningness/eveningness and depressive symptoms in T2D patients in the United States and in Thailand. PARTICIPANTS: T2D patients (n=182) from an endocrinology clinic in Chicago, Illinois and six hospitals in Thailand (n=251) were enrolled. METHODS: Diabetes history was collected...
June 15, 2017: Behavioral Sleep Medicine
https://www.readbyqxmd.com/read/28615771/comparative-study-of-psychiatric-manifestations-among-type-i-and-type-ii-diabetic-patients
#3
Rupesh Chaudhary, Pankaj Kumar, Akhil Chopra, Sandeep Chabbra, Parminder Singh
BACKGROUND: Anxiety and depressive disorders belong to the most common psychiatric disorders worldwide. They are generally seen in individuals who suffer from chronic diseases, such as diabetes mellitus (DM). The prevalence of depression among diabetics ranges from 8.5% to 32.5%, while that for anxiety it is up to 30%. In this study, we try to compare the mental health problems faced by those with Type I and Type II DM. MATERIALS AND METHODS: Fifty patients diagnosed with Type I diabetes (T1D) and Type II diabetes each presenting to Medicine and Endocrinology Department were assessed with Hamilton Depression Rating Scale (HAM-D) for depression and Hamilton Anxiety Rating Scale (HAM-A) for anxiety...
May 2017: Indian Journal of Psychological Medicine
https://www.readbyqxmd.com/read/28610556/toileting-behaviors-and-overactive-bladder-in-patients-with-type-2-diabetes-a-cross-sectional-study-in-china
#4
Dongjuan Xu, Ran Cheng, Aixia Ma, Meng Zhao, Kefang Wang
BACKGROUND: Overactive bladder is more prevalent in patients with type 2 diabetes than in those without diabetes. Unhealthy toileting behaviors may be associated with the development and worsening of overactive bladder symptoms. However, little is known about the relationships between toileting behaviors and overactive bladder in patients with diabetes. This study aimed to identify unhealthy toileting behaviors that patients with type 2 diabetes adopted to empty their bladders and investigate the relationships between toileting behaviors and overactive bladder...
June 13, 2017: BMC Urology
https://www.readbyqxmd.com/read/28608050/metabolic-and-androgen-profile-in-underweight-women-with-polycystic-ovary-syndrome
#5
Olympia E Anastasiou, Ali Canbay, Dagmar Fuhrer, Susanne Reger-Tan
INTRODUCTION: Polycystic ovary syndrome (PCOS) is a disorder associated with insulin resistance and obesity. Aim of our study is to clarify the prevalence of underweight in PCOS patients and whether metabolic and androgen profiles of PCOS differ depending on normal or low body weight. METHODS: Out of 1269 consecutive patients with PCOS recruited from the Department of Endocrinology and Metabolism at the University of Duisburg-Essen, 19 patients (1.5%) were underweight and were compared to 375 lean PCOS subjects (29...
June 12, 2017: Archives of Gynecology and Obstetrics
https://www.readbyqxmd.com/read/28606343/pharmacologic-management-of-type-2-diabetes-mellitus-available-therapies
#6
James Thrasher
Choices for the treatment of type 2 diabetes mellitus (T2DM) have multiplied as our understanding of the underlying pathophysiologic defects has evolved. Treatment should target multiple defects in T2DM and follow a patient-centered approach that considers factors beyond glycemic control, including cardiovascular risk reduction. The American Association of Clinical Endocrinologists/American College of Endocrinology and the American Diabetes Association recommend an initial approach consisting of lifestyle changes and monotherapy, preferably with metformin...
July 1, 2017: American Journal of Cardiology
https://www.readbyqxmd.com/read/28604326/screening-for-gestational-diabetes-mellitus-in-a-south-african-population-prevalence-comparison-of-diagnostic-criteria-and-the-role-of-risk-factors
#7
Sumaiya Adam, Paul Rheeder
BACKGROUND: The prevalence of gestational diabetes mellitus (GDM) is increasing. Most major world organisations now recommend universal screening for GDM based on the International Association of Diabetes in Pregnancy Study Groups (IADPSG) criteria. Currently there is a lack of consensus on the diagnostic criteria for GDM used in South Africa (SA). The Society for Endocrinology, Metabolism and Diabetes of South Africa's revised guidelines recommend the use of the IADPSG criteria for the diagnosis of GDM...
May 24, 2017: South African Medical Journal, Suid-Afrikaanse Tydskrif Vir Geneeskunde
https://www.readbyqxmd.com/read/28601583/should-we-officially-recognise-obesity-as-a-disease
#8
EDITORIAL
The Lancet Diabetes Endocrinology
No abstract text is available yet for this article.
June 7, 2017: Lancet Diabetes & Endocrinology
https://www.readbyqxmd.com/read/28593616/new-insights-on-diabetes-in-turner-syndrome-results-from-an-observational-study-in-adulthood
#9
Daniela Ibarra-Gasparini, Paola Altieri, Emanuela Scarano, Annamaria Perri, Antonio M Morselli-Labate, Uberto Pagotto, Laura Mazzanti, Renato Pasquali, Alessandra Gambineri
OBJECTIVE: To explore the characteristics of diabetes mellitus in adults with Turner syndrome. DESIGN: Observational study consisting of a prospective phase after the access of adults with Turner syndrome to the Endocrinology Unit (median period of follow-up 15.6, interquartile range: 12.0-24.5 months) and a retrospective collection of data from the diagnosis of Turner syndrome until the time of access to the Endocrinology Unit. A total of 113 Italian Turner syndrome patients were included in the study...
June 7, 2017: Endocrine
https://www.readbyqxmd.com/read/28592005/-type-2-diabetes-in-the-child-and-adolescent-consensus-in-china
#10
(no author information available yet)
No abstract text is available yet for this article.
June 2, 2017: Zhonghua Er Ke za Zhi. Chinese Journal of Pediatrics
https://www.readbyqxmd.com/read/28591390/long-term-follow-up-of-growth-hormone-secreting-pituitary-adenomas-submitted-to-endoscopic-endonasal-surgery
#11
Caroline Martins Dos Santos Leopoldo, Felippe Martins Dos Santos Leopoldo, Américo Rubens Leite Dos Santos, José Carlos Esteves Veiga, José Viana Lima, Nilza Maria Scalissi, Paulo Roberto Lazarini, Ricardo Landini Lutaif Dolci
Objective: The aim of this study was to evaluate the results of the endoscopic transsphenoidal technique for growth hormone (GH)-secreting adenomas. Methods: A retrospective analysis based on medical records of 23 acromegalic patients submitted to endoscopic transsphenoidal surgery. Biochemical control was defined as basal GH < 1ng/ml, nadir GH < 0.4ng/ml after glucose load and age-adjusted IGF-1 normal at the last follow-up. Results: The overall endocrinological remission rate was 39...
May 2017: Arquivos de Neuro-psiquiatria
https://www.readbyqxmd.com/read/28589154/prolonged-ketosis-in-a-patient-with-euglycemic-diabetic-ketoacidosis-secondary-to-dapagliflozin
#12
Shreya Pujara, Adriana Ioachimescu
Since the approval of sodium-glucose cotransporter 2 (SGLT2) inhibitors by the US Food and Drug Administration for type 2 diabetes, there have been several reports of euglycemic diabetic ketoacidosis in patients using this class of medication. We present a case of euglycemic diabetic ketoacidosis where ketonemia and glucosuria persisted well beyond the expected effect of dapagliflozin. Our patient is a 50-year-old woman with type 2 diabetes since age 35 who was taking metformin and dapagliflozin. She presented with fatigue, constipation, and 3 days of reduced oral intake...
April 2017: Journal of Investigative Medicine High Impact Case Reports
https://www.readbyqxmd.com/read/28588968/who-and-national-lists-of-essential-medicines-in-mexico-central-and-south-america-and-the-caribbean-are-they-adequate-to-promote-paediatric-endocrinology-and-diabetes-care
#13
Amanda Rowlands, Alejandra Acosta-Gualandri, Jaime Guevara-Aguirre, Jean-Pierre Chanoine
Paediatric endocrinology and diabetes is a paediatric specialty with less common conditions and higher cost medicines. Access to medicines for our specialty in low and middle income countries remains limited. We analysed the content of the WHO (children and adults) and of all available national Model Lists of Essential Medicines (EMLs) for Mexico, the Caribbean, Central and South America from a paediatric endocrinology and diabetes standpoint. A master list of medicines deemed necessary in paediatric endocrinology and diabetes was established and compared with the WHO and national EMLs, taking into account the gross national income...
November 2016: BMJ Global Health
https://www.readbyqxmd.com/read/28588159/ramadan-perspective-epidemiology-and-education-in-diabetes-rapeed-study
#14
N I Siddiqui, M Kamrul-Hasan, M A Hossain, P K Chanda, M A Bakar, M Rahman, M A Kader
Ramadan fasting is one of the five pillars of Islam and is obligatory for all healthy adult and adolescent Muslims. A significant number of patients with diabetes observe fasting during Ramadan. The objectives of this Ramadan Perspective Epidemiology and Education in Diabetes (RAPEED) study were to find out the current knowledge, attitude, and practices about Ramadan fasting among people with diabetes in Bangladesh. This retrospective cross-sectional study recruited 648 subjects with diabetes mellitus attending the Endocrinology outpatient department of a tertiary level hospital of Bangladesh within two months of the end of Ramadan in 2016...
April 2017: Mymensingh Medical Journal: MMJ
https://www.readbyqxmd.com/read/28585130/factors-associated-with-peripheral-neuropathy-in-type-2-diabetes-subclinical-versus-confirmed-neuropathy
#15
Yogendranathsing Unmar, Mohammad Ishraq Zafar, Feng Gao
This study determined the prevalence of diabetic peripheral neuropathy (DPN) and subclinical DPN (sDPN) in patients with type 2 diabetes mellitus (T2DM) using nerve conduction study (NCS) as a diagnostic tool. We also investigated the factors associated with the development of sDPN and compared factors between the sDPN and confirmed DPN (cDPN). This cross-sectional study involved 240 T2DM patients who were successively admitted to the endocrinology wards of Wuhan Union Hospital over the period of January to December 2014...
June 2017: Journal of Huazhong University of Science and Technology. Medical Sciences
https://www.readbyqxmd.com/read/28574011/coexistence-of-celiac-disease-type-1-diabetes-mellitus-in-children
#16
Preeti Singh, Anju Seth, Praveen Kumar, Sushma Sajjan
BACKGROUND & OBJECTIVES: Type 1 diabetes mellitus (T1DM) and celiac disease (CD) tend to co-exist due to similar underlying genetic predisposition. Failure to recognize CD in patients with T1DM predisposes them to complications. The present study was aimed to assess children with T1DM for the presence of CD. METHODS: This was a retrospective analysis of the records of children with T1DM attending paediatric endocrinology clinic at a tertiary care hospital in north India from January 2006 to May 2014...
January 2017: Indian Journal of Medical Research
https://www.readbyqxmd.com/read/28569356/effects-of-laparoscopic-sleeve-gastrectomy-on-parathyroid-hormone-vitamin-d-calcium-phosphorus-and-albumin%C3%A2-levels
#17
Mehmet Mihmanli, Riza Gurhan Isil, Canan Tulay Isil, Sinan Omeroglu, Pinar Sayin, Sibel Oba, Feyza Yener Ozturk, Yuksel Altuntas
BACKGROUND: Laparoscopic sleeve gastrectomy (LSG) reduces obesity-related co-morbidities, such as diabetes, hypertension, and hyperlipidemia. Endocrinological abnormalities may occur as undesired side effects. Most centers routinely prescribe folic acid, cyanocobalamin (vitB12), and protein replacement in the postoperative period, but 25-OH-vitamin-D3 (vitD) and intact parathyroid hormone (iPTH) levels are not routinely followed up. The aim of this study was to identify the effects of LSG on iPTH, vitD, calcium (Ca), phosphorus (P), alkaline phosphatase (ALP), and albumin levels...
May 31, 2017: Obesity Surgery
https://www.readbyqxmd.com/read/28566439/mechanisms-in-endocrinology-the-sexually-dimorphic-role-of-androgens-in-human-metabolic-disease
#18
Lina Schiffer, Punith Kempegowda, Wiebke Arlt, Michael W O'Reilly
Female androgen excess and male androgen deficiency manifest with an overlapping adverse metabolic phenotype, including abdominal obesity, insulin resistance, type 2 diabetes mellitus, non-alcoholic fatty liver disease and an increased risk of cardiovascular disease. Here we review the impact of androgens on metabolic target tissues in an attempt to unravel the complex mechanistic links with metabolic dysfunction; we also evaluate clinical studies examining the associations between metabolic disease and disorders of androgen metabolism in men and women...
May 31, 2017: European Journal of Endocrinology
https://www.readbyqxmd.com/read/28565889/renal-function-markers-and-metformin-eligibility
#19
Carlos Tavares Bello, Ricardo Castro Fonseca, Francisco Sousa Santos, João Sequeira Duarte, Jorge Azinheira, Carlos Vasconcelos
BACKGROUND: Metformin is the cornerstone of the pharmacological therapy for type 2 Diabetes (T2D). It belongs to the biguanide class of drugs and it improves hepatic insulin resistance and enhances GLP-1 and peptide YY secretion. Although being considered safe regarding hypoglycemic risk, renal dysfunction remains the main obstacle to its use due to the underlying risk of lactic acidosis. In the recent past many authors used creatinine values as the decisive marker when it came to choose between pharmacological agents in DM...
May 31, 2017: Minerva Endocrinologica
https://www.readbyqxmd.com/read/28553599/serum-vitamin-b12-levels-in-type-2-diabetes-patients-on-metformin-compared-to-those-never-on-metformin-a-cross-sectional-study
#20
Nishant Raizada, Viveka P Jyotsna, Vishnubhatla Sreenivas, Nikhil Tandon
CONTEXT: There are limited data about the effect of metformin use on serum Vitamin B12 levels in type 2 diabetes patients from India. AIMS: We studied serum Vitamin B12 levels in patients with type 2 diabetes mellitus who were receiving metformin and compared them to those never treated with metformin. SUBJECTS AND METHODS: A total of 183 patients ("metformin" group 121, "no metformin" group 63) of type 2 diabetes from the endocrinology clinic of a tertiary care center in North India were studied...
May 2017: Indian Journal of Endocrinology and Metabolism
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