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Pelvic girdle

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https://www.readbyqxmd.com/read/28803818/a-homozygous-dpm3-mutation-in-a-patient-with-alpha-dystroglycan-related-limb-girdle-muscular-dystrophy
#1
P Y K Van den Bergh, Y Sznajer, V Van Parys, W van Tol, R A Wevers, D J Lefeber, L Xu, M Lek, D G MacArthur, K Johnson, L Phillips, A Töpf, V Straub
Defects of O-linked glycosylation of alpha-dystroglycan cause a wide spectrum of muscular dystrophies ranging from severe congenital muscular dystrophy associated with abnormal brain and eye development to mild limb girdle muscular dystrophy. We report a female patient who developed isolated pelvic girdle muscle weakness and wasting, which became symptomatic at age 42. Exome sequencing uncovered a homozygous c.131T > G (p.Leu44Pro) substitution in DPM3, encoding dolichol-P-mannose (DPM) synthase subunit 3, leading to a 50% reduction of enzymatic activity...
July 17, 2017: Neuromuscular Disorders: NMD
https://www.readbyqxmd.com/read/28796694/myoepithelioma-of-soft-tissue-with-both-squamous-and-adipocytic-metaplasia
#2
Ashley Elsensohn, Joshua H Mo, Tyler J Maly, Patrick K Lee, Sebastien de Feraudy
Soft tissue, or cutaneous, myoepitheliomas are rare tumors arising solely from a myoepithelial origin. These neoplasms are typically associated with uncertain differentiation and can contain cellular morphologies that include spindle, plasmacytoid, epithelioid, or clear cell forms. Soft tissue myoepitheliomas are commonly found on the lower limbs and in the pelvic girdle but can occur throughout the body. A small minority display heterogenous differentiation, typically osseous or cartilaginous in nature. Squamous and adipocytic cell types are much rarer...
August 3, 2017: American Journal of Dermatopathology
https://www.readbyqxmd.com/read/28775180/sick-leave-and-medication-use-in-pregnancy-a-european-web-based-study
#3
Bich Thuy Truong, Angela Lupattelli, Petter Kristensen, Hedvig Nordeng
BACKGROUND AND OBJECTIVE: A comparison of sick leave in pregnancy between countries is difficult as most studies have been conducted in single countries in Scandinavia. The objective of this study was to explore patterns of and reasons for sick leave during pregnancy on a multinational level, focusing on medication use but also differences in sick leave policies. DESIGN AND SETTING: Cross-sectional, web-based study in 12 European countries from October 2011 to February 2012...
August 3, 2017: BMJ Open
https://www.readbyqxmd.com/read/28774422/polymyalgia-rheumatica
#4
REVIEW
Miguel A González-Gay, Eric L Matteson, Santos Castañeda
Polymyalgia rheumatica is an inflammatory disease that affects the shoulder, the pelvic girdles, and the neck, usually in individuals older than 50 years. Increases in acute phase reactants are typical of polymyalgia rheumatica. The disorder might present as an isolated condition or in association with giant cell arteritis. Several diseases, including inflammatory rheumatic and autoimmune diseases, infections, and malignancies can mimic polymyalgia rheumatica. Imaging techniques have identified the presence of bursitis in more than half of patients with active disease...
July 31, 2017: Lancet
https://www.readbyqxmd.com/read/28761797/correlated-evolution-of-sternal-keel-length-and-ilium-length-in-birds
#5
Tao Zhao, Di Liu, Zhiheng Li
The interplay between the pectoral module (the pectoral girdle and limbs) and the pelvic module (the pelvic girdle and limbs) plays a key role in shaping avian evolution, but prior empirical studies on trait covariation between the two modules are limited. Here we empirically test whether (size-corrected) sternal keel length and ilium length are correlated during avian evolution using phylogenetic comparative methods. Our analyses on extant birds and Mesozoic birds both recover a significantly positive correlation...
2017: PeerJ
https://www.readbyqxmd.com/read/28718250/qing-qi-rickshaw-a-boon-or-bane-for-public-transportation-a-study-of-road-traffic-injury-patterns-involving-qing-qi-rickshaws-in-karachi-pakistan
#6
Muhammad Muzzammil, Muhammad Saeed Minhas, Jahanzeb Effendi, Syed Jahanzeb, Ayesha Mughal, Abdul Qadir
BACKGROUND: The three-wheeler Qing-qi and Compressed Natural Gas (CNG) auto-rickshaws were introduced in Karachi to meet the transportation demand of the growing population. These vehicles have directly or indirectly been implicated in a number of road traffic violations as well as road accidents. This study aims to describe the crash characteristics and injury patterns for Qing-qi rickshaw occupants and other road users hit by Qing-qi rickshaw in Karachi, Pakistan. METHODS: An Observational/ Descriptive study was conducted at Accident & Emergency and Orthopaedic Surgery Department, Jinnah Post Graduate Medical Centre, Karachi Pakistan from July 2014 to June 2015...
April 2017: Journal of Ayub Medical College, Abbottabad: JAMC
https://www.readbyqxmd.com/read/28676358/anatomy-and-physiology-of-the-pelvic-floor
#7
REVIEW
Sarah M Eickmeyer
Understanding the anatomic relationship of the pelvic floor muscles with the pelvic girdle, spine, and hips aids the rehabilitation provider in diagnosis, management, and appropriate referrals. The bony anatomy of the pelvic girdle consists of 3 bones and 3 joints. The pelvic floor muscles are comprised mainly of the levator ani muscles with somatic innervation from the lumbosacral plexus. The bony and muscular pelvis is highly interconnected to the hip and gluteal musculature, which together provide support to the internal organs and core muscles...
August 2017: Physical Medicine and Rehabilitation Clinics of North America
https://www.readbyqxmd.com/read/28674657/variation-in-the-pelvic-and-pectoral-girdles-of-australian-oligo-miocene-mekosuchine-crocodiles-with-implications-for-locomotion-and-habitus
#8
Michael D Stein, Adam Yates, Suzanne J Hand, Michael Archer
Australian Oligo-Miocene mekosuchines (Crocodylia; Crocodyloidea) display wide diversity in cranial shape and inferred hunting strategies. Terrestrial habitus has been inferred for these distinctive predators. A direct morphological signal for locomotion can be expected in the postcrania, particularly the pelvic and pectoral girdles. Here we describe fossil materials of the girdles, which chart their morphological variation in the subfamily from Eocene through to Middle Miocene. Over this period, both girdles undergo significant morphological changes...
2017: PeerJ
https://www.readbyqxmd.com/read/28674644/europatitan-eastwoodi-a-new-sauropod-from-the-lower-cretaceous-of-iberia-in-the-initial-radiation-of-somphospondylans-in-laurasia
#9
Fidel Torcida Fernández-Baldor, José Ignacio Canudo, Pedro Huerta, Miguel Moreno-Azanza, Diego Montero
The sauropod of El Oterillo II is a specimen that was excavated from the Castrillo de la Reina Formation (Burgos, Spain), late Barremian-early Aptian, in the 2000s but initially remained undescribed. A tooth and elements of the axial skeleton, and the scapular and pelvic girdle, represent it. It is one of the most complete titanosauriform sauropods from the Early Cretaceous of Europe and presents an opportunity to deepen our understanding of the radiation of this clade in the Early Cretaceous and study the paleobiogeographical relationships of Iberia with Gondwana and with other parts of Laurasia...
2017: PeerJ
https://www.readbyqxmd.com/read/28671155/low-back-pain-in-pregnant-women-attending-antenatal-clinic-the-aminu-kano-teaching-hospital-experience
#10
Mustapha Ibrahim Usman, Muhammad Kabir Abubakar, Shamsuddeen Muhammad, Ayyuba Rabiu, Ibrahim Garba
BACKGROUND: The profound physiologic effects of pregnancy affect the musculoskeletal system. Pregnant women are at increased risks of low back/pelvic girdle pains. OBJECTIVE: To determine the incidence of low back/pelvic girdle pains among pregnant women. MATERIALS AND METHODS: This was a cross-sectional study conducted from May 1 to June 30, 2016, among consenting pregnant women at Aminu Kano Teaching Hospital. Ethical approval was obtained from the Hospital Ethics Committee...
July 2017: Annals of African Medicine
https://www.readbyqxmd.com/read/28660634/effects-of-phylogeny-and-locomotor-style-on-the-allometry-of-body-mass-and-pelvic-dimensions-in-birds
#11
Matthew V Anten-Houston, Marcello Ruta, D Charles Deeming
The pelvic girdle provides physical support and attachment for the hind limb musculature. In birds there is variability in pelvic morphology across different orders and this has been used as evidence for various types of locomotion. However, the morphological variation of pelvic bones has yet to be studied systematically in birds. Therefore, we investigated basic allometric relationships among female body mass (as a size proxy) and various pelvic measurements in a phylogenetic context. We also examined in detail the inter-relationships among various pelvic measurements...
June 28, 2017: Journal of Anatomy
https://www.readbyqxmd.com/read/28649268/muscle-development-in-the-shark-scyliorhinus-canicula-implications-for-the-evolution-of-the-gnathostome-head-and-paired-appendage-musculature
#12
Janine M Ziermann, Renata Freitas, Rui Diogo
BACKGROUND: The origin of jawed vertebrates was marked by profound reconfigurations of the skeleton and muscles of the head and by the acquisition of two sets of paired appendages. Extant cartilaginous fish retained numerous plesiomorphic characters of jawed vertebrates, which include several aspects of their musculature. Therefore, myogenic studies on sharks are essential in yielding clues on the developmental processes involved in the origin of the muscular anatomy. RESULTS: Here we provide a detailed description of the development of specific muscular units integrating the cephalic and appendicular musculature of the shark model, Scyliorhinus canicula...
2017: Frontiers in Zoology
https://www.readbyqxmd.com/read/28610361/description-of-a-new-species-of-gymnotocinclus-from-the-rio-tocantins-basin-with-phylogenetic-analysis-of-the-subfamily-hypoptopomatinae-siluriformes-loricariidae
#13
Fábio F Roxo, Gabriel S C Silva, Luz Eneida Ochoa, Cláudio H Zawadzki
Gymnotocinclus canoeiro n. sp. of the Hypoptopomatinae is described from small tributaries of the upper rio Tocantins basin. It is distinguished from G. anosteos by having five characters: (1) the presence of body dermal plates, (2) the pectoral girdle not exposed in ventral view, (3) the pelvic spine longer than pectoral spine in males, (4) the pectoral fin with seven to eight branched rays, and (5) the presence of an adipose fin. Furthermore, maximum likelihood (ML) analysis was used to estimate a molecular phylogeny from previously published data of one nuclear (F-Reticulon 4) and three mitochondrial (16S RNA, COI and CytB) genes...
May 17, 2017: Zootaxa
https://www.readbyqxmd.com/read/28583280/clinical-value-of-fdg-pet-ct-for-the-evaluation-of-rheumatic-diseases-rheumatoid-arthritis-polymyalgia-rheumatica-and-relapsing-polychondritis
#14
REVIEW
Kazuo Kubota, Hiroyuki Yamashita, Akio Mimori
FDG is a tracer for visualizing glucose metabolism. PET/CT using FDG is widely used for the diagnosis of cancer, because glycolysis is elevated in cancer cells. Similarly, active inflammatory tissue also exhibits elevated glucose metabolism because of glycolysis in activated macrophages and proliferating fibroblasts. Elevated FDG uptake by active inflammatory tissues, such as those affected by arthritis, vasculitis, lymphadenitis, and chondritis, has enabled the diagnosis of inflammatory diseases using FDG-PET/CT...
July 2017: Seminars in Nuclear Medicine
https://www.readbyqxmd.com/read/28582642/movement-of-the-sacroiliac-joint-during-the-active-straight-leg-raise-test-in-patients-with-long-lasting-severe-sacroiliac-joint-pain
#15
Thomas J Kibsgård, Stephan M Röhrl, Olav Røise, Bengt Sturesson, Britt Stuge
BACKGROUND: The Active Straight Leg Raise is a functional test used in the assessment of pelvic girdle pain, and has shown to have good validity, reliability and responsiveness. The Active Straight Leg Raise is considered to examine the patients' ability to transfer load through the pelvis. It has been hypothesized that patients with pelvic girdle pain lack the ability to stabilize the pelvic girdle, probably due to instability or increased movement of the sacroiliac joint. This study examines the movement of the sacroiliac joints during the Active Straight Leg Raise in patients with pelvic girdle pain...
August 2017: Clinical Biomechanics
https://www.readbyqxmd.com/read/28575052/myogenic-differentiation-of-vcp-disease-induced-pluripotent-stem-cells-a-novel-platform-for-drug-discovery
#16
Katrina J Llewellyn, Angèle Nalbandian, Lan N Weiss, Isabela Chang, Howard Yu, Bibo Khatib, Baichang Tan, Vanessa Scarfone, Virginia E Kimonis
Valosin Containing Protein (VCP) disease is an autosomal dominant multisystem proteinopathy caused by mutations in the VCP gene, and is primarily associated with progressive muscle weakness, including atrophy of the pelvic and shoulder girdle muscles. Currently, no treatments are available and cardiac and respiratory failures can lead to mortality at an early age. VCP is an AAA ATPase multifunction complex protein and mutations in the VCP gene resulting in disrupted autophagic clearance. Due to the rarity of the disease, the myopathic nature of the disorder, ethical and practical considerations, VCP disease muscle biopsies are difficult to obtain...
2017: PloS One
https://www.readbyqxmd.com/read/28567473/body-contouring-after-massive-weight-loss-a-personal-integrated-approach
#17
Manuel Maia, Diana Costa Santos
BACKGROUND: After massive weight loss, patients typically presented with skin redundancy, which causes enormous esthetic, physical, medical and psychological problems. The growing number of patients with these sequelae triggered an increase in the search for body contouring procedures, which in turn produced an important development in the post-bariatric reconstructive surgery. METHODS: The author describes the principles of a personal approach in post-bariatric reconstructive surgery...
May 31, 2017: Aesthetic Plastic Surgery
https://www.readbyqxmd.com/read/28551465/spinal-fusion-limits-upper-body-range-of-motion-during-gait-without-inducing-compensatory-mechanisms-in-adolescent-idiopathic-scoliosis-patients
#18
R M Holewijn, I Kingma, M de Kleuver, J J P Schimmel, N L W Keijsers
INTRODUCTION: Previous studies show a limited alteration of gait at normal walking speed after spinal fusion surgery for adolescent idiopathic scoliosis (AIS), despite the presumed essential role of spinal mobility during gait. This study analyses how spinal fusion affects gait at more challenging walking speeds. More specifically, we investigated whether thoracic-pelvic rotations are reduced to a larger extent at higher gait speeds and whether compensatory mechanisms above and below the stiffened spine are present...
May 17, 2017: Gait & Posture
https://www.readbyqxmd.com/read/28547886/the-suction-mechanism-of-the-pipid-frog-pipa-pipa-linnaeus-1758
#19
David Cundall, Edward Fernandez, Frances Irish
Most suction-feeding, aquatic vertebrates create suction by rapidly enlarging the oral cavity and pharynx. Forceful enlargement of the pharynx is powered by longitudinal muscles that retract skeletal elements of the hyoid, more caudal branchial arches, and, in many fish, the pectoral girdle. This arrangement was thought to characterize all suction-feeding vertebrates. However, it does not exist in the permanently aquatic, tongueless Pipa pipa, an Amazonian frog that can catch fish. Correlating high-speed (250 and 500 fps) video records with anatomical analysis and functional tests shows that fundamental features of tetrapod body design are altered to allow P...
May 25, 2017: Journal of Morphology
https://www.readbyqxmd.com/read/28544276/pregnancy-and-pelvic-girdle-pain-analysis-of-pelvic-belt-on-pain
#20
Jeanne Bertuit, Charlotte Eloise Van Lint, Marcel Rooze, Véronique Feipel
AIMS: To analyse pain and functional capacity in women with pelvic girdle pain and to evaluate the effect of pelvic belt on these parameters. Two types of belts were to compare. BACKGROUND: Pelvic girdle pain is very common during pregnancy. To prevent and relieve pelvic pain, women can use a set of techniques and tools such as a pelvic belt. While scientific evidence is lacking, commercial industries suggest the effectiveness of pelvic belts. DESIGN: Randomized control trial...
May 25, 2017: Journal of Clinical Nursing
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