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https://www.readbyqxmd.com/read/29451342/deleterious-effect-of-anti-angiotensin-ii-type-1-receptor-antibodies-detected-pretransplant-on-kidney-graft-outcomes-is-both-proper-and-synergistic-with-donor-specific-anti-hla-antibodies
#1
Jorge Malheiro, Sandra Tafulo, Leonídio Dias, La Salete Martins, Isabel Fonseca, Idalina Beirão, António Castro-Henriques, António Cabrita
AIM: Both donor-specific antibodies (DSA) and anti-angiotensin II type 1 receptor antibodies (AT1R-abs) have been associated with poor graft outcomes after kidney transplantation (KT). We aimed to understand the impact of pretransplant AT1R-abs with or without concomitant DSA on KT outcomes. METHODS: Seventy-six patients transplanted in 2009 were studied. DSA (MFI>1000) and/or AT1R-abs (>10UI) were detected by solid-phase assays in pre-KT sera. Multivariable Cox regression models were used to determine independent predictors of outcomes: acute rejection (AR) and graft failure...
February 16, 2018: Nephrology
https://www.readbyqxmd.com/read/29443537/a-randomized-clinical-trial-to-evaluate-attached-hamstring-anterior-cruciate-ligament-graft-maturity-with-magnetic-resonance-imaging
#2
Shaohua Liu, Hong Li, Hongyue Tao, Yaying Sun, Shiyi Chen, Jiwu Chen
BACKGROUND: The hamstring tendons are commonly harvested for anterior cruciate ligament (ACL) reconstruction with detachment of the tibial insertion. Retaining the insertion may help to preserve vascularity and viability of the graft and bypass the stages of avascular necrosis and revascularization, which might be beneficial to graft maturity. PURPOSE: To investigate and compare graft maturity by magnetic resonance imaging (MRI) after ACL reconstruction with preservation or detachment of hamstring tendon tibial insertion at up to 2 years...
February 1, 2018: American Journal of Sports Medicine
https://www.readbyqxmd.com/read/29438635/twenty-year-follow-up-study-comparing-operative-versus-nonoperative-treatment-of-anterior-cruciate-ligament-ruptures-in-high-level-athletes
#3
Daan T van Yperen, Max Reijman, Eline M van Es, Sita M A Bierma-Zeinstra, Duncan E Meuffels
BACKGROUND: An anterior cruciate ligament (ACL) rupture has major consequences at midterm follow-up, with an increasing chance of developing an old knee in a young patient. The long-term (≥20 years) effects of the operative and nonoperative treatment of ACL ruptures are still unclear. PURPOSE: To compare the long-term treatment outcomes of operative versus nonoperative treatment of ACL ruptures in high-level athletes. STUDY DESIGN: Cohort study; Level of evidence, 2...
February 1, 2018: American Journal of Sports Medicine
https://www.readbyqxmd.com/read/29421837/all-inside-single-bundle-reconstruction-of-the-anterior-cruciate-ligament-with-the-anterior-half-of-the-peroneus-longus-tendon-compared-to-the-semitendinosus-tendon-a-two-year-follow-up-study
#4
Mingguang Bi, Chen Zhao, Shuijun Zhang, Bin Yao, Zheping Hong, Qing Bi
The anterior half of the peroneus longus tendon (AHPLT) has been reported to be acceptable for ligament reconstruction with respect to strength and safety. However, there is little information regarding the clinical outcomes after using the AHPLT compared with other autograft tendons. A prospective randomized controlled study was performed to compare the results of 62 cases of all-inside anatomical single-bundle anterior cruciate ligament (ACL) reconstruction using the AHPLT and 62 cases using semitendinosus graft with an average of 30...
February 8, 2018: Journal of Knee Surgery
https://www.readbyqxmd.com/read/29380050/tibial-tunnel-placement-in-anatomic-anterior-cruciate-ligament-reconstruction-a-comparison-study-of-outcomes-between-patient-specific-drill-template-versus-conventional-arthroscopic-techniques
#5
Meisong Zhu, Sijing Li, Zexin Su, Xiaoqi Zhou, Peng Peng, Jianyi Li, Jinping Wang, Lijun Lin
INTRODUCTION: Accurate anatomic graft tunnel positioning is essential for the successful application of anatomic anterior cruciate ligament (ACL) reconstruction. The accurate insertion of the tibial tunnel (TT) remains challenging. Here, we explored a novel strategy of patient-specific drill template (PDT) for the placement of TT in ACL reconstruction and assessed its efficacy and accuracy. MATERIALS AND METHODS: TT placement was randomized and performed by use of the PDT technique in 40 patients (PDT group) and the conventional arthroscopic technique in 38 patients (Arthroscopic group)...
January 27, 2018: Archives of Orthopaedic and Trauma Surgery
https://www.readbyqxmd.com/read/29287949/comparison-of-clinical-outcomes-after-anterior-cruciate-ligament-reconstruction-using-a-hybrid-graft-versus-a-hamstring-autograft
#6
Hong-De Wang, Shi-Jun Gao, Ying-Ze Zhang
PURPOSE: This study aimed to compare the clinical outcomes of patients who underwent anterior cruciate ligament (ACL) reconstruction with a hybrid graft versus an autograft after 3 years of follow-up. METHODS: Among 57 patients with an ACL injury who underwent ACL reconstruction, 28 patients received a hybrid graft (gracilis and semitendinosus tendon autograft plus a soft tissue allograft) and 29 patients received an autograft (gracilis and semitendinosus tendon autograft)...
December 26, 2017: Arthroscopy: the Journal of Arthroscopic & related Surgery
https://www.readbyqxmd.com/read/29244525/20-year-outcomes-of-anterior-cruciate-ligament-reconstruction-with-hamstring-tendon-autograft-the-catastrophic-effect-of-age-and-posterior-tibial-slope
#7
Lucy J Salmon, Emma Heath, Hawar Akrawi, Justin P Roe, James Linklater, Leo A Pinczewski
BACKGROUND: No well-controlled studies have compared the long-term outcome of anterior cruciate ligament (ACL) reconstruction with hamstring tendon autograft between adolescents and adults. Increased posterior tibial slopes (PTSs) have been reported in the ACL-injured versus controls, but the effect of PTS on the outcome after reconstruction is relatively unexplored. PURPOSE: To compare the prospective longitudinal outcome of "isolated" ACL ruptures treated with anatomic endoscopic ACL reconstruction using hamstring tendon autograft over 20 years in adolescent and adult cohorts and to examine factors for repeat ACL injury...
December 1, 2017: American Journal of Sports Medicine
https://www.readbyqxmd.com/read/29167416/second-look-arthroscopic-evaluation-and-clinical-outcomes-of-anatomic-anterior-cruciate-ligament-reconstruction-with-autograft-and-hybrid-graft-a-retrospective-study
#8
Hongtao Xu, Jiangtao Dong, Dongmei Xin, Jian Zhang, Kai Kang, Shijun Gao
BACKGROUND Graft choice is very controversial. This study compared the second-look evaluation and clinical outcomes of anatomic ACL-R using a thin autograft versus a thick hybrid graft. MATERIAL AND METHODS Sixty-eight patients who had received ACL-R with hamstring autograft or autograft-allograft hybrid graft accepted second-look arthroscopy were grouped (autograft: n=31, age: 32.8±8.9, Male/Female: 16/15, and hybrid graft: n=37, age: 33.9±8.4, Male/Female: 27/10). Patients were evaluated with the functional score and KT-1000 test before reconstruction...
November 23, 2017: Medical Science Monitor: International Medical Journal of Experimental and Clinical Research
https://www.readbyqxmd.com/read/29159673/double-bundle-anterior-cruciate-ligament-reconstruction-is-better-than-single-bundle-reconstruction-in-terms-of-objective-assessment-but-not-in-terms-of-subjective-score
#9
Faisal Ahmed Hashem El-Sherief, Wael Abdelkarim Aldahshan, Yaser Elsayed Wahd, Ashraf Mohamed Abdelaziz, Hany Abdel Gawwad Soliman, Tohamy Goda Hassan, Hassan Fathy Elbehairy, Adel Hamed Awadallah
PURPOSE: A comparison of clinical outcomes between double-bundle (DB) and single-bundle (SB) anterior cruciate ligament (ACL) reconstruction for patients with ACL injury. METHODS: Sixty patients were treated with either SB (n = 30) or DB (n = 30) ACL reconstruction between 2011 and 2012. The hamstring tendons were autografted with suspensory fixation on the femoral side, while a bio-absorbable interference screw was used for fixation on the tibial side. These patients were evaluated using Lysholm score, International Knee Documentation Committee (IKDC) forms (both objective and subjective), Lachman test, pivot shift test, and KT 1000 arthrometer...
November 20, 2017: Knee Surgery, Sports Traumatology, Arthroscopy: Official Journal of the ESSKA
https://www.readbyqxmd.com/read/29138919/low-re-rupture-rate-with-bptb-autograft-and-semitendinosus-gracilis-autograft-with-preserved-insertions-in-acl-reconstruction-surgery-in-sports-persons
#10
Ravi Gupta, Munish Sood, Anubhav Malhotra, Gladson David Masih, Anil Kapoor, Mukta Raghav, Mehar Dhillon
PURPOSE: To compare the results of bone-patellar tendon-bone graft (BPTB), semitendinosus-gracilis graft with preserved insertions (STGPI) and semitendinosus-gracilis-free graft (STGF) in terms of graft failure, objective mechanical stability, functional outcome, and return to sports in elite and recreational sports persons. It was hypothesized that the STGPI graft provided superior outcome as compared to the other two grafts. METHODS: Two hundred and forty-nine elite and recreational players who underwent ACL reconstruction surgery, with BPTB graft (N = 80), STGPI graft (N = 85), and STGF graft (N = 84) with a minimum follow-up of 2 years, were assessed using clinical tests, knee arthrometer (KT 1000™), single-leg hop test, Lysholm knee score, Tegner's activity scale, and return to sports...
November 14, 2017: Knee Surgery, Sports Traumatology, Arthroscopy: Official Journal of the ESSKA
https://www.readbyqxmd.com/read/29114625/revision-anterior-cruciate-ligament-reconstruction-with-contralateral-hamstring-tendon-grafts-6-years-follow-up
#11
Claudio Legnani, Stefania Zini, Enrico Borgo, Alberto Ventura
Purpose  The purpose of this study was to retrospectively evaluate the clinical outcome of revision anterior cruciate ligament (ACL) reconstruction with contralateral hamstring tendon autografts, specifically with regard to patient satisfaction, return to preinjury activity level, and postoperative functional outcomes. Methods  Between 2004 and 2011, 23 patients underwent revision ACL reconstruction with contralateral autogenous hamstring tendon grafts and were retrospectively reviewed at an average follow-up of 6...
March 2017: Joints
https://www.readbyqxmd.com/read/29067474/restoring-tibiofemoral-alignment-during-acl-reconstruction-results-in-better-knee-biomechanics
#12
Frantzeska Zampeli, Ioannis Terzidis, João Espregueira-Mendes, Jim-Dimitris Georgoulis, Manfred Bernard, Evangelos Pappas, Anastasios D Georgoulis
PURPOSE: Anterior cruciate ligament (ACL) reconstruction (ACLR) aims to restore normal knee joint function, stability and biomechanics and in the long term avoid joint degeneration. The purpose of this study is to present the anatomic single bundle (SB) ACLR that emphasizes intraoperative correction of tibiofemoral subluxation that occurs after ACL injury. It was hypothesized that this technique leads to optimal outcomes and better restoration of pathological tibiofemoral joint movement that results from ACL deficiency (ACLD)...
October 24, 2017: Knee Surgery, Sports Traumatology, Arthroscopy: Official Journal of the ESSKA
https://www.readbyqxmd.com/read/29065270/medial-meniscus-resection-increases-and-medial-meniscus-repair-preserves-anterior-knee-laxity-a-cohort-study-of-4497-patients-with-primary-anterior-cruciate-ligament-reconstruction
#13
Riccardo Cristiani, Erik Rönnblad, Björn Engström, Magnus Forssblad, Anders Stålman
BACKGROUND: There are still controversies regarding the effects on knee laxity of additional meniscus resection or repair in the setting of anterior cruciate ligament reconstruction (ACLR). Hypothesis/Purpose: The purpose was to determine the effects on knee laxity of resection or repair of medial meniscus (MM) or lateral meniscus (LM) injuries in the ACLR knee. The hypothesis was that patients with an additional meniscus resection would have significantly increased postoperative knee laxity versus that of an isolated ACLR, whereas patients with meniscus repair would have laxity comparable to that of an isolated ACLR...
October 1, 2017: American Journal of Sports Medicine
https://www.readbyqxmd.com/read/29051899/surgical-treatment-of-segond-fractures-in-acute-anterior-cruciate-ligament-reconstruction
#14
Andrea Ferretti, Edoardo Monaco, Megan Rianne Wolf, Matteo Guzzini, Angelo De Carli, Daniele Mazza
BACKGROUND: The Segond fracture is an avulsion-type fracture located on the anterolateral aspect of the tibia associated with a ligament recently termed the anterolateral ligament. This injury has been described as pathognomonic for an anterior cruciate ligament (ACL) tear and is associated with a higher grade pivot shift. PURPOSE: To present and report 2-year clinical outcomes of a surgical technique for acute ACL reconstruction with fixation of a concomitant Segond fracture...
October 2017: Orthopaedic Journal of Sports Medicine
https://www.readbyqxmd.com/read/29035543/speciated-monitoring-of-gas-phase-organic-peroxy-radicals-by-chemical-ionization-mass-spectrometry-cross-reactions-between-ch3o2-ch3-co-o2-ch3-3co2-and-c-c6h11o2
#15
Barbara Nozière, David R Hanson
Organic peroxy radicals ("RO2", with R organic) are key intermediates in most oxygen-rich systems, where organic compounds are oxidized (natural environment, flames, combustion engines, living organisms, etc). But, until recently, techniques able to monitor simultaneously and distinguish between RO2 species ("speciated" detection) have been scarce, which has limited the understanding of complex systems containing these radicals. Mass spectrometry using proton transfer ionization has been shown previously to detect individual gas-phase RO2 separately...
October 30, 2017: Journal of Physical Chemistry. A
https://www.readbyqxmd.com/read/29032309/anterior-cruciate-ligament-revision-with-achilles-tendon-allograft-in-young-athletes
#16
S Zaffagnini, A Grassi, G M Marcheggiani Muccioli, T Roberti Di Sarsina, L Macchiarola, M Mosca, M P Neri, M Marcacci
BACKGROUND: Return to sport after revision ACL reconstruction is a controversial topic, several studies reported the results of different techniques and graft in sportsman, presenting an incredibly wide range of return to the same pre-injury activity level, from 0% to 100%. The purpose of this study was to evaluate the clinical outcomes and return to sport rate in young athletes after non anatomic double-bundle revision ACL reconstruction with Achilles allograft. HYPOTHESIS: The present revision technique was effective in terms of stability, return to sport and functional outcomes...
October 13, 2017: Orthopaedics & Traumatology, Surgery & Research: OTSR
https://www.readbyqxmd.com/read/28974333/effect-of-the-timing-of-anterior-cruciate-ligament-reconstruction-on-clinical-and-stability-outcomes-a%C3%A2-systematic-review-and-meta-analysis
#17
Yong Seuk Lee, O-Sung Lee, Seung Hoon Lee, Teo Seow Hui
PURPOSE: The purpose of this systematic review and meta-analysis was to evaluate the effect of the timing of anterior cruciate ligament (ACL) reconstruction on clinical and stability outcomes by analyzing high-quality studies that assessed timing as a primary objective. METHODS: The MEDLINE, EMBASE, and Cochrane database were systematically searched. The inclusion criteria were as follows: (1) English articles, (2) noncomparative study or relevant study reporting clinical and/or stability results, and (3) timing of the ACL reconstruction as a primary objective...
September 30, 2017: Arthroscopy: the Journal of Arthroscopic & related Surgery
https://www.readbyqxmd.com/read/28969952/outcome-of-hamstring-autograft-with-preserved-insertions-compared-with-free-hamstring-autograft-in-anterior-cruciate-ligament-surgery-at-2-year-follow-up
#18
Ravi Gupta, Raj Bahadur, Anubhav Malhotra, Gladson David Masih, Munish Sood, Parmanand Gupta, Vivek Kumar Mathur
PURPOSE: To compare mechanical stability, functional outcome, and level of return to sports activity in patients undergoing anterior cruciate ligament (ACL) reconstruction with a free hamstring graft versus a graft with preserved insertions at 2-year follow-up. METHODS: This study was a prospective, single-blind (the evaluator was blinded), randomized trial of 110 adult professional athletes who were randomly allocated into 2 groups. Group 1 consisted of 55 patients who underwent ACL reconstruction with hamstring tendon autograft with preserved insertions (technique 1), and group 2 consisted of 55 patients who underwent ACL reconstruction with free hamstring tendon autograft (technique 2)...
December 2017: Arthroscopy: the Journal of Arthroscopic & related Surgery
https://www.readbyqxmd.com/read/28951643/acl-reconstruction-using-femoral-rigid-fix-and-tibial-bio-intrafix-devices
#19
Rahul Singh, Sujit Kumar Tripathy, Monappa A Naik, Premjit Sujir, Sharath K Rao
OBJECTIVES: The objective of this study is to report the clinical and functional outcomes of Hamstring graft ACL reconstruction fixed with femoral Rigid-fix and tibial Bio-intrafix devices. METHODS: In a prospective study, the clinical (Lysholm score) and functional outcomes (International Knee Documentation Committee, IKDC) of 44 patients who underwent autologus hamstring graft ACL reconstruction using femoral Rigid-fix and tibial Bio-intrafix devices, were evaluated at the end of one year...
July 2017: Journal of Clinical Orthopaedics and Trauma
https://www.readbyqxmd.com/read/28892648/long-term-outcomes-of-anterior-cruciate-ligament-reconstruction-using-either-synthetics-with-remnant-preservation-or-hamstring-autografts-a-10-year-longitudinal-study
#20
Tianwu Chen, Peng Zhang, Jiwu Chen, Yinghui Hua, Shiyi Chen
BACKGROUND: The optimal graft choice of anterior cruciate ligament (ACL) reconstruction remains controversial. PURPOSE: To compare the outcomes, especially the long-term cumulative failure rate, of ACL reconstruction using either synthetics with remnant preservation or hamstring autografts (4-strand semitendinosus and gracilis tendons). STUDY DESIGN: Cohort study; Level of evidence, 2. METHODS: A total of 133 patients who underwent ACL reconstruction (synthetics: n = 43; hamstring autografts: n = 90) between July 2004 and December 2007 were included...
October 2017: American Journal of Sports Medicine
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