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https://www.readbyqxmd.com/read/29352379/magnetic-resonance-with-diffusion-weighted-imaging-improves-assessment-of-focal-liver-lesions-in-patients-with-potentially-resectable-pancreatic-cancer-on-ct
#1
Sun Kyung Jeon, Jeong Min Lee, Ijin Joo, Dong Ho Lee, Su Joa Ahn, Hyunsik Woo, Myoung Seok Lee, Jin-Young Jang, Joon Koo Han
PURPOSE: To investigate added value of MRI to preoperative staging MDCT for evaluation of focal liver lesions (FLLs) in potentially resectable pancreatic ductal adenocarcinomas (PDACs). MATERIALS AND METHODS: In patients with potentially resectable PDACs after staging MDCT (n=167), characteristics of FLLs were scored as benign, indeterminate or metastases on an MDCT set and combined MDCT and MRI set by two readers, independently. Size of hepatic lesions was measured and detection rate of hepatic metastasis unsuspected by MDCT and diagnostic yield of MRI for FLLs were assessed...
January 19, 2018: European Radiology
https://www.readbyqxmd.com/read/29349947/incidence-rate-of-atypical-femoral-fracture-after-bisphosphonates-treatment-in-korea
#2
Young Kyun Lee, Soyeon Ahn, Kyoung Min Kim, Chang Suk Suh, Kyung Hoi Koo
BACKGROUND: Atypical femoral fracture (AFF) has been high-lightened, because it was associated with the long-term use of bisphosphonate. Comparing western countries, the incidence rate of AFF was unclear in East Asian patients. Our purposes were to estimate the incidence rate of radiologically defined AFF in Korea, and to determine the association between occurrence of AFF and long-term use of bisphosphonate. METHODS: We conducted a hospital-based, retrospective cohort study in patients aged ≥ 45 years, who took bisphosphonate...
January 29, 2018: Journal of Korean Medical Science
https://www.readbyqxmd.com/read/29349946/validation-study-of-a-korean-version-of-the-abbreviated-university-of-california-los-angeles-ptsd-reaction-index-abb-ucla-ptsd-ri-for-adolescents
#3
Tae Ho Kim, Doug Hyun Han, Seo Koo Yoo, Jung Jae Lee, Ji Eun Kim, Un Sun Chung
BACKGROUND: We aimed to verify a Korean version of the Abbreviated University of California, Los Angeles, Post-Traumatic Stress Disorder Reaction Index (Abb-UCLA-PTSD RI-Korean version) among Korean adolescents to assess post-traumatic stress in this population. METHODS: We recruited 1,254 adolescents who completed the Abb-UCLA-PTSD RI-Korean version scale, the Child Report of Post-Traumatic Symptoms (CROPS), the Lifetime Incidence of Traumatic Events (LITE), and the Children's Depression Inventory (CDI)...
January 29, 2018: Journal of Korean Medical Science
https://www.readbyqxmd.com/read/29349821/biodegradable-electronic-systems-in-3d-heterogeneously-integrated-formats
#4
Jan-Kai Chang, Hui-Ping Chang, Qinglei Guo, Jahyun Koo, Chih-I Wu, John A Rogers
Biodegradable electronic systems represent an emerging class of technology with unique application possibilities, from temporary biomedical implants to "green" consumer gadgets. This paper introduces materials and processing methods for 3D, heterogeneously integrated devices of this type, with various functional examples in sophisticated forms of silicon-based electronics. Specifically, techniques for performing multilayer assembly by transfer printing and for fabricating layer-to-layer vias and interconnects by lithographic procedures serve as routes to biodegradable, 3D integrated circuits composed of functional building blocks formed using specialized approaches or sourced from commercial semiconductor foundries...
January 19, 2018: Advanced Materials
https://www.readbyqxmd.com/read/29348061/effects-of-wavelength-mixing-ratio-and-photoperiod-on-microalgal-biomass-and-lipid-production-in-a-two-phase-culture-system-using-led-illumination
#5
Phunlap Sirisuk, Chae-Hun Ra, Gwi-Taek Jeong, Sung-Koo Kim
Blue and red light-emitting diodes (LEDs) were used to study the effects of wavelength mixing ratios, photoperiod regimes, and green wavelength stress on Nannochloropsis salina, Isochrysis galbana, and Phaeodactylum tricornutum cell biomass and lipid production. The maximum specific growth rates of I. galbana and P. tricornutum were obtained under a 50:50 mixing ratio of blue and red wavelength LEDs; that of N. salina was obtained under red LED. Maximum cell biomass for N. salina and P. tricornutum was 0.75 and 1...
January 4, 2018: Bioresource Technology
https://www.readbyqxmd.com/read/29341891/long-term-treadmill-exercise-improves-memory-impairment-through-restoration-of-decreased-synaptic-adhesion-molecule-1-2-3-induced-by-transient-cerebral-ischemia-in-the-aged-gerbil-hippocampus
#6
Ji Hyeon Ahn, Joon Ha Park, Jinseu Park, Myoung Cheol Shin, Jun Hwi Cho, In Hye Kim, Jeong-Hwi Cho, Tae-Kyeong Lee, Jae-Chul Lee, Bich Na Shin, Young-Myeong Kim, Choong Hyun Lee, In Koo Hwang, Il Jun Kang, Bai Hui Chen, Bing Chun Yan, Young Joo Lee, Moo-Ho Won, Soo Young Choi
Exercise improves cognitive impairments induced by transient cerebral ischemia and modulates synaptic adhesion molecules. In this study, we investigated effects of long-term treadmill exercise on cognitive impairments and its relation to changes of synaptic cell adhesion molecule (SynCAM) 1/2/3 in the hippocampus after 5 min of transient cerebral ischemia in aged gerbils. Animals were assigned to sedentary and exercised groups, given treadmill exercise for 4 consecutive weeks from 5 days after transient ischemia and evaluated cognitive function through passive avoidance test and Morris water maze test...
January 13, 2018: Experimental Gerontology
https://www.readbyqxmd.com/read/29340839/the-cumulative-incidence-and-risk-factors-of-postoperative-inguinal-hernia-in-patients-undergoing-radical-prostatectomy
#7
Ja Yoon Ku, Chan Ho Lee, Won Young Park, Nam Kyung Lee, Seung Hyun Baek, Hong Koo Ha
BACKGROUND: The aim of this study is to investigate the cumulative incidence and risk factors of postoperative inguinal hernia (PIH) in patients undergoing radical prostatectomy, i.e., laparoscopic prostatectomy (LRP) and robot-assisted laparoscopic prostatectomy (RARP). METHODS: This study included 1124 patients who had undergone radical prostatectomy or transurethral resection of bladder tumor from 2011-2016. We compared the cumulative incidence of PIH in the radical prostatectomy groups (460; LRP 341, RARP 119) and the control group (664; transurethral resection of bladder tumor), and we then analyzed the risk factors (age, operative methods, previous abdominal operative history, thickness and width of external oblique muscle and rectus muscle, thickness of abdominal subcutaneous fat layer at Hesselbach's triangle level, body mass index, prostate-specific antigen, operative time, specimen weight, Gleason score, and pathology T-stage) of PIH in the radical prostatectomy groups...
January 16, 2018: International Journal of Clinical Oncology
https://www.readbyqxmd.com/read/29338929/differential-anxiety-like-behavior-hpa-responsiveness-and-host-resistance-in-mice-with-different-circling-preference
#8
Dongsoo Kim, Hyojin Koo, Kicheol Cheon
Relationships between behavioral sidedness and immune responses in previous studies have differed depending on behavior tests and severity of biological stress in mice. It was necessary to elucidate the psychophysiological mediators that connect behavioral sidedness and immune responses. This study investigated interrelationships among anxiety-like behavior, the HPA axis responsiveness, and host-resistance to bacterial infection. Mice that preferred clockwise circling had lower locomotor activities, higher anxiety-like behavior, and faster activation of the HPA axis than mice that preferred counterclockwise circling...
December 27, 2017: Journal of Neuroimmunology
https://www.readbyqxmd.com/read/29337163/utility-of-ultra-deep-sequencing-for-detection-of-varicella-zoster-virus-antiviral-resistance-mutations
#9
Mélanie Mercier-Darty, David Boutolleau, Raphaël Lepeule, Christophe Rodriguez, Sonia Burrel
We report the first application of ultra-deep sequencing (UDS) to varicella-zoster virus (VZV) genotypic antiviral testing in a case of acyclovir-resistant VZV infection initially detected by Sanger sequencing within a deeply immunocompromised heart transplant recipient. As added-value compared to Sanger analysis, UDS revealed complex dynamics of viral population under antiviral pressure. Varicella-zoster virus (VZV) is a ubiquitous human herpesvirus affecting populations worldwide. VZV is commonly acquired in youth whose primary infection usually manifests as benign varicella (chickenpox)...
January 11, 2018: Antiviral Research
https://www.readbyqxmd.com/read/29333323/alveolar-ridge-preservation-with-an-open-healing-approach-using-single-layer-or-double-layer-coverage-with-collagen-membranes
#10
Ho-Keun Choi, Hag-Yeon Cho, Sung-Jo Lee, In-Woo Cho, Hyun-Seung Shin, Ki-Tae Koo, Hyun-Chang Lim, Jung-Chul Park
Purpose: The aim of this prospective pilot study was to compare alveolar ridge preservation (ARP) procedures with open-healing approach using a single-layer and a double-layer coverage with collagen membranes using radiographic and clinical analyses. Methods: Eleven molars from 9 healthy patients requiring extraction of the maxillary or mandibular posterior teeth were included and allocated into 2 groups. After tooth extraction, deproteinized bovine bone mineral mixed with 10% collagen was grafted into the socket and covered either with a double-layer of resorbable non-cross-linked collagen membranes (DL group, n=6) or with a single-layer (SL group, n=5)...
December 2017: Journal of Periodontal & Implant Science
https://www.readbyqxmd.com/read/29333322/a-randomized-controlled-clinical-study-of-periodontal-tissue-regeneration-using-an-extracellular-matrix-based-resorbable-membrane-in-combination-with-a-collagenated-bovine-bone-graft-in-intrabony-defects
#11
Sulhee Kim, Hyeyoon Chang, Jin Wook Hwang, Sungtae Kim, Ki-Tae Koo, Tae-Il Kim, Yang-Jo Seol, Yong-Moo Lee, Young Ku, Jong-Ho Lee, In-Chul Rhyu
Purpose: The purpose of this study was to investigate the feasibility of regenerative therapy with a collagenated bone graft and resorbable membrane in intrabony defects, and to evaluate the effects of the novel extracellular matrix (ECM)-based membrane clinically and radiologically. Methods: Periodontal tissue regeneration procedure was performed using an ECM-based resorbable membrane in combination with a collagenated bovine bone graft in intrabony defects around the teeth and implants...
December 2017: Journal of Periodontal & Implant Science
https://www.readbyqxmd.com/read/29331412/anti-leukemic-effects-of-ppar%C3%AE-ligands
#12
Somi Ryu, Dae Seong Kim, Myoung Woo Lee, Ji Won Lee, Ki Woong Sung, Hong Hoe Koo, Keon Hee Yoo
The peroxisome proliferator-activated receptor (PPAR) γ, a subtype of PPARs, is a member of the nuclear receptor family. PPARγ and its ligands contribute to various types of diseases including cancer. Given that currently developed therapies against leukemia are not very effective or safe, PPARγ ligands have been shown to be a new class of compounds with the potential to treat hematologic malignancies, particularly leukemia. The capability of PPARγ ligands to induce apoptosis, inhibit proliferation, and promote differentiation of leukemia cells suggests it has significant potential as a drug against leukemia...
January 10, 2018: Cancer Letters
https://www.readbyqxmd.com/read/29330856/reproductive-history-breast-feeding-and-risk-of-triple-negative-breast-cancer-the-breast-cancer-etiology-in-minorities-bem-study
#13
Esther M John, Lisa M Hines, Amanda I Phipps, Jocelyn Koo, Teri A Longacre, Sue A Ingles, Kathy B Baumgartner, Martha L Slattery, Anna H Wu
Few risk factors have been identified for triple negative breast cancer (TNBC) which lacks expression of estrogen receptor (ER), progesterone receptor (PR), and human epidermal growth factor receptor 2 (HER2). This more aggressive subtype disproportionately affects some racial/ethnic minorities and is associated with lower survival. We pooled data from three population-based studies (558 TNBC and 5,111 controls) and examined associations of TNBC risk with reproductive history and breast-feeding. We estimated odds ratios (OR) and 95% confidence intervals (CI) using multivariable logistic regression...
January 13, 2018: International Journal of Cancer. Journal International du Cancer
https://www.readbyqxmd.com/read/29330577/asymptomatic-population-reference-values-for-three-knee-patient-reported-outcomes-measures-evaluation-of-an-electronic-data-collection-system-and-implications-for-future-international-multi-centre-cohort-studies
#14
James M McLean, Oscar Brumby-Rendell, Ryan Lisle, Jacob Brazier, Kieran Dunn, Tiffany Gill, Catherine L Hill, Daniel Mandziak, Jordan Leith
OBJECTIVES: The aim was to assess whether the Knee Society Score, Oxford Knee Score (OKS) and Knee Injury and Osteoarthritis Outcome Score (KOOS) were comparable in asymptomatic, healthy, individuals of different age, gender and ethnicity, across two remote continents. The purpose of this study was to establish normal population values for these scores using an electronic data collection system. HYPOTHESIS: There is no difference in clinical knee scores in an asymptomatic population when comparing age, gender and ethnicity, across two remote continents...
January 12, 2018: Archives of Orthopaedic and Trauma Surgery
https://www.readbyqxmd.com/read/29329888/associations-between-cartilage-proteoglycan-density-and-patient-outcomes-12months-following-anterior-cruciate-ligament-reconstruction
#15
Brian Pietrosimone, Daniel Nissman, Darin A Padua, J Troy Blackburn, Matthew S Harkey, Robert A Creighton, Ganesh M Kamath, Kaitlin Healy, Randy Schmitz, Jeffrey B Driban, Steve W Marshall, Joanne M Jordan, Jeffrey T Spang
BACKGROUND: Lower proteoglycan density (PGD) of the articular cartilage may be an early marker of osteoarthritis following anterior cruciate ligament (ACL) reconstruction (ACL-R). The purpose this study was to determine associations between the Knee Injury and Osteoarthritis Outcomes Score (KOOS) and PGD of the articular cartilage in the femur and tibia 12-months following ACL-R. METHODS: We evaluated KOOS pain, symptoms, function in activities of daily living (ADL), function in sport and recreation (Sport), and quality of life (QOL), as well as PGD using T1rho magnetic resonance imaging in 18 individuals 12...
January 9, 2018: Knee
https://www.readbyqxmd.com/read/29329669/prevalence-and-predictors-of-symptom-resolution-and-functional-restoration-in-the-index-knee-following-knee-arthroplasty-a-longitudinal-study
#16
Daniel L Riddle
OBJECTIVES: To determine the prevalence of a one- to two-year postsurgical pain-free state and pain plus symptom-free state as well as function restoration following knee arthroplasty (KA). A second purpose was to identify predictors of these outcomes. DESIGN: An inception cohort from the Osteoarthritis Initiative (OAI) dataset, a nine-year NIH funded cohort study of persons with or at high risk for knee osteoarthritis was studied. SETTING: Subjects were recruited from the communities of four sites in the Midwest, Eastern and Southeastern United States...
January 9, 2018: Archives of Physical Medicine and Rehabilitation
https://www.readbyqxmd.com/read/29328959/impact-of-individual-and-neighborhood-factors-on-disparities-in-prostate-cancer-survival
#17
Mindy C DeRouen, Clayton W Schupp, Jocelyn Koo, Juan Yang, Andrew Hertz, Salma Shariff-Marco, Myles Cockburn, David O Nelson, Sue A Ingles, Esther M John, Scarlett L Gomez
BACKGROUND: We addressed the hypothesis that individual-level factors act jointly with social and built environment factors to influence overall survival for men with prostate cancer and contribute to racial/ethnic and socioeconomic (SES) survival disparities. METHODS: We analyzed multi-level data, combining (1) individual-level data from the California Collaborative Prostate Cancer Study, a population-based study of non-Hispanic White (NHW), Hispanic, and African American prostate cancer cases (N = 1800) diagnosed from 1997 to 2003, with (2) data on neighborhood SES (nSES) and social and built environment factors from the California Neighborhoods Data System, and (3) data on tumor characteristics, treatment and follow-up through 2009 from the California Cancer Registry...
January 9, 2018: Cancer Epidemiology
https://www.readbyqxmd.com/read/29328299/coherent-modulation-up-to-100-gbd-16qam-using-silicon-organic-hybrid-soh-devices
#18
S Wolf, H Zwickel, C Kieninger, M Lauermann, W Hartmann, Y Kutuvantavida, W Freude, S Randel, C Koos
We demonstrate the generation of higher-order modulation formats using silicon-based inphase/quadrature (IQ) modulators at symbol rates of up to 100 GBd. Our devices exploit the advantages of silicon-organic hybrid (SOH) integration, which combines silicon-on-insulator waveguides with highly efficient organic electro-optic (EO) cladding materials to enable small drive voltages and sub-millimeter device lengths. In our experiments, we use an SOH IQ modulator with a π-voltage of 1.6 V to generate 100 GBd 16QAM signals...
January 8, 2018: Optics Express
https://www.readbyqxmd.com/read/29328155/fast-switching-optically-isotropic-liquid-crystal-nano-droplets-with-improved-depolarization-and-kerr-effect-by-doping-high-k-nanoparticles
#19
Byeonggon Kim, Hyun Gyu Kim, Gyu-Yeop Shim, Ji-Sub Park, Kyung-Il Joo, Dong-Jin Lee, Joun-Ho Lee, Ji-Ho Baek, Byeong Koo Kim, Yoonseuk Choi, Hak-Rin Kim
We proposed and analyzed an optically isotropic nano-droplet liquid crystal (LC) doped with high k nanoparticles (NPs), exhibiting enhanced Kerr effects, which could be operated with reduced driving voltages. For enhancing the contrast ratio together with the light efficiencies, the LC droplet sizes were adjusted to be shorter than the wavelength of visible light to reduce depolarization effects by optical scattering of the LC droplets. Based on the optical analysis of the depolarization effects, the influence of the relationship between the LC droplet size and the NP doping ratio on the Kerr effect change was investigated...
January 10, 2018: Applied Optics
https://www.readbyqxmd.com/read/29328135/autostereoscopic-3d-display-system-with-dynamic-fusion-of-the-viewing-zone-under-eye-tracking-principles-setup-and-evaluation-invited
#20
Ki-Hyuk Yoon, Min-Koo Kang, Hwasun Lee, Sung-Kyu Kim
We study optical technologies for viewer-tracked autostereoscopic 3D display (VTA3D), which provides improved 3D image quality and extended viewing range. In particular, we utilize a technique-the so-called dynamic fusion of viewing zone (DFVZ)-for each 3D optical line to realize image quality equivalent to that achievable at optimal viewing distance, even when a viewer is moving in a depth direction. In addition, we examine quantitative properties of viewing zones provided by the VTA3D system that adopted DFVZ, revealing that the optimal viewing zone can be formed at viewer position...
January 1, 2018: Applied Optics
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