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https://www.readbyqxmd.com/read/28631268/network-for-investigation-of-delirium-across-the-u-s-advancing-the-field-of-delirium-with-a-new-interdisciplinary-research-network
#1
EDITORIAL
Donna M Fick, Andrew D Auerbach, Michael S Avidan, Jan Busby-Whitehead, E Wesley Ely, Richard N Jones, Edward R Marcantonio, Dale M Needham, Pratik Pandharipande, Thomas N Robinson, Eva M Schmitt, Thomas G Travison, Sharon K Inouye
No abstract text is available yet for this article.
June 20, 2017: Journal of the American Geriatrics Society
https://www.readbyqxmd.com/read/28612089/the-intensive-care-delirium-research-agenda-a-multinational-interprofessional-perspective
#2
REVIEW
Pratik P Pandharipande, E Wesley Ely, Rakesh C Arora, Michele C Balas, Malaz A Boustani, Gabriel Heras La Calle, Colm Cunningham, John W Devlin, Julius Elefante, Jin H Han, Alasdair M MacLullich, José R Maldonado, Alessandro Morandi, Dale M Needham, Valerie J Page, Louise Rose, Jorge I F Salluh, Tarek Sharshar, Yahya Shehabi, Yoanna Skrobik, Arjen J C Slooter, Heidi A B Smith
Delirium, a prevalent organ dysfunction in critically ill patients, is independently associated with increased morbidity. This last decade has witnessed an exponential growth in delirium research in hospitalized patients, including those critically ill, and this research has highlighted that delirium needs to be better understood mechanistically to help foster research that will ultimately lead to its prevention and treatment. In this invited, evidence-based paper, a multinational and interprofessional group of clinicians and researchers from within the fields of critical care medicine, psychiatry, pediatrics, anesthesiology, geriatrics, surgery, neurology, nursing, pharmacy, and the neurosciences sought to address five questions: (1) What is the current standard of care in managing ICU delirium? (2) What have been the major recent advances in delirium research and care? (3) What are the common delirium beliefs that have been challenged by recent trials? (4) What are the remaining areas of uncertainty in delirium research? (5) What are some of the top study areas/trials to be done in the next 10 years? Herein, we briefly review the epidemiology of delirium, the current best practices for management of critically ill patients at risk for delirium or experiencing delirium, identify recent advances in our understanding of delirium as well as gaps in knowledge, and discuss research opportunities and barriers to implementation, with the goal of promoting an integrated research agenda...
June 13, 2017: Intensive Care Medicine
https://www.readbyqxmd.com/read/28550403/healthcare-utilization-and-costs-in-ards-survivors-a-1-year-longitudinal-national-us-multicenter-study
#3
A Parker Ruhl, Minxuan Huang, Elizabeth Colantuoni, Taruja Karmarkar, Victor D Dinglas, Ramona O Hopkins, Dale M Needham
PURPOSE: To evaluate (1) post-discharge healthcare utilization and estimated costs in ARDS survivors, and (2) the association between patient and intensive care-related variables, and 6-month patient status, with subsequent hospitalization and costs. METHODS: Longitudinal cohort study enrolling from four ARDSNet trials in 44 US hospitals. Healthcare utilization was collected via structured interviews at 6 and 12 months post-ARDS, and hospital costs estimated via the Medical Expenditure Panel Survey...
May 26, 2017: Intensive Care Medicine
https://www.readbyqxmd.com/read/28542632/evaluation-of-a-strategy-for-enrolling-the-families-of-critically-ill-patients-in-research-using-limited-human-resources
#4
Alison E Turnbull, Mohamed D Hashem, Anahita Rabiee, An To, Caroline M Chessare, Dale M Needham
RATIONALE: Clinical trials of interventions aimed at the families of intensive care unit (ICU) patients have proliferated but recruitment for these trials can be challenging. OBJECTIVES: To evaluate a strategy for recruiting families of patients currently being treated in an ICU using limited human resources and time-varying daily screening over 7 consecutive days. METHODS: We screened the Johns Hopkins Hospital medical ICU census 7 days per week to identify eligible family members...
2017: PloS One
https://www.readbyqxmd.com/read/28537429/core-outcome-measures-for-clinical-research-in-acute-respiratory-failure-survivors-an-international-modified-delphi-consensus-study
#5
Dale M Needham, Kristin A Sepulveda, Victor D Dinglas, Caroline M Chessare, Lisa Aronson Friedman, Clifton O Bingham Iii, Alison E Turnbull
RATIONALE: Research evaluating acute respiratory failure (ARF) survivors' outcomes after hospital discharge has substantial heterogeneity in measurement instruments used, creating barriers to synthesizing study data. OBJECTIVES: To identify a minimum set of core outcome measures that are essential to include in all clinical research studies evaluating ARF survivors after discharge. METHODS: A three-round modified Delphi consensus process with 77 participants (47% female, 55% outside USA), including clinical researchers from >16 countries across 6 continents, patients/caregivers, clinicians, and research funders...
May 24, 2017: American Journal of Respiratory and Critical Care Medicine
https://www.readbyqxmd.com/read/28480212/understanding-early-goal-directed-mobilization-in-the-surgical-intensive-care-unit
#6
EDITORIAL
Navya Reddy Alugubelli, Awsse Al-Ani, Dale M Needham, Ann M Parker
No abstract text is available yet for this article.
April 2017: Annals of Translational Medicine
https://www.readbyqxmd.com/read/28463657/instrumental-activities-of-daily-living-after-critical-illness-a-systematic-review
#7
Ramona O Hopkins, Mary R Suchyta, Biren B Kamdar, Emily Darowski, James C Jackson, Dale M Needham
BACKGROUND: Poor functional status is common after critical illness, and can adversely impact intensive care unit (ICU) survivors' abilities to live independently. Instrumental activities of daily living (IADL), which encompass complex tasks necessary for independent living are a particularly important component of post-ICU functional outcome. OBJECTIVE: To conduct a systematic review of studies evaluating IADLs in survivors of critical illness. DATA SOURCES: We searched PubMed, CINAHL, Cochrane Library, SCOPUS, and Web of Science for all relevant English-language studies published through December 31, 2016...
May 2, 2017: Annals of the American Thoracic Society
https://www.readbyqxmd.com/read/28448673/network-for-investigation-of-delirium-across-the-u-s-nidus-advancing-the-field-of-delirium-with-a-new-interdisciplinary-research-network
#8
EDITORIAL
Donna M Fick, Andrew D Auerbach, Michael S Avidan, Jan Busby-Whitehead, E Wesley Ely, Richard N Jones, Edward R Marcantonio, Dale M Needham, Pratik Pandharipande, Thomas N Robinson, Eva M Schmitt, Thomas G Travison, Sharon K Inouye
No abstract text is available yet for this article.
May 1, 2017: Journal of Gerontological Nursing
https://www.readbyqxmd.com/read/28448162/joblessness-and-lost-earnings-after-ards-in-a-1-year-national-multicenter-study
#9
Biren B Kamdar, Minxuan Huang, Victor D Dinglas, Elizabeth Colantuoni, Till M von Wachter, Ramona O Hopkins, Dale M Needham
RATIONALE: Following acute respiratory distress syndrome (ARDS), joblessness is common, but poorly understood. OBJECTIVES: To evaluate the timing of return to work following ARDS, and associated risk factors, lost earnings, and changes in healthcare coverage Methods: Over 12-month longitudinal follow-up, ARDS survivors from 43 U.S. ARDSNet hospitals provided employment and healthcare coverage data via structured telephone interviews. Factors associated with the timing of return to work were assessed using Fine and Gray regression analysis...
April 27, 2017: American Journal of Respiratory and Critical Care Medicine
https://www.readbyqxmd.com/read/28444070/brazilian-version-of-the-functional-status-score-for-the-icu-translation-and-cross-cultural-adaptation
#10
Vinicius Zacarias Maldaner da Silva, Jose Aires de Araújo, Gerson Cipriano, Mariela Pinedo, Dale M Needham, Jennifer M Zanni, Fernando Silva Guimarães
Objective: The aim of the present study was to translate and cross-culturally adapt the Functional Status Score for the intensive care unit (FSS-ICU) into Brazilian Portuguese. Methods: This study consisted of the following steps: translation (performed by two independent translators), synthesis of the initial translation, back-translation (by two independent translators who were unaware of the original FSS-ICU), and testing to evaluate the target audience's understanding...
January 2017: Revista Brasileira de Terapia Intensiva
https://www.readbyqxmd.com/read/28379571/safety-and-feasibility-of-a-protocolized-approach-to-in-bed-cycling-exercise-in-the-intensive-care-unit-quality-improvement-project
#11
Ibtehal Kimawi, Bryanna Lamberjack, Archana Nelliot, Amy Lee Toonstra, Jennifer Zanni, Minxuan Huang, Earl Mantheiy, Michelle E Kho, Dale M Needham
Background: : In-bed, supine cycle ergometry as a part of early rehabilitation in the intensive care unit (ICU) appears to be safe, feasible, and beneficial, but no standardized protocol exists. A standardized protocol may help guide use of cycle ergometry in the ICU. Objective: We investigated whether a standardized protocol for in-bed cycling is safe and feasible, and results in cycling for a longer duration and achieves a higher resistance. Design: A quality improvement (QI) project was conducted...
March 31, 2017: Physical Therapy
https://www.readbyqxmd.com/read/28375853/core-domains-for-clinical-research-in-acute-respiratory-failure-survivors-an-international-modified-delphi-consensus-study
#12
Alison E Turnbull, Kristin A Sepulveda, Victor D Dinglas, Caroline M Chessare, Clifton O Bingham, Dale M Needham
OBJECTIVES: To identify the "core domains" (i.e., patient outcomes, health-related conditions, or aspects of health) that relevant stakeholders agree are essential to assess in all clinical research studies evaluating the outcomes of acute respiratory failure survivors after hospital discharge. DESIGN: A two-round consensus process, using a modified Delphi methodology, with participants from 16 countries, including patient and caregiver representatives. Prior to voting, participants were asked to review 1) results from surveys of clinical researchers, acute respiratory failure survivors, and caregivers that rated the importance of 19 preliminary outcome domains and 2) results from a qualitative study of acute respiratory failure survivors' outcomes after hospital discharge, as related to the 19 preliminary outcome domains...
June 2017: Critical Care Medicine
https://www.readbyqxmd.com/read/28355099/validity-of-the-posttraumatic-stress-symptoms-14-instrument-in-acute-respiratory-failure-survivors
#13
Ann M Parker, Sina Nikayin, O Joseph Bienvenu, Dale M Needham
No abstract text is available yet for this article.
June 2017: Annals of the American Thoracic Society
https://www.readbyqxmd.com/read/28291092/measuring-patient-mobility-in-the-icu-using-a-novel-noninvasive-sensor
#14
Andy J Ma, Nishi Rawat, Austin Reiter, Christine Shrock, Andong Zhan, Alex Stone, Anahita Rabiee, Stephanie Griffin, Dale M Needham, Suchi Saria
OBJECTIVES: To develop and validate a noninvasive mobility sensor to automatically and continuously detect and measure patient mobility in the ICU. DESIGN: Prospective, observational study. SETTING: Surgical ICU at an academic hospital. PATIENTS: Three hundred sixty-two hours of sensor color and depth image data were recorded and curated into 109 segments, each containing 1,000 images, from eight patients. INTERVENTIONS: None...
April 2017: Critical Care Medicine
https://www.readbyqxmd.com/read/28289812/the-icm-research-agenda-on-intensive-care-unit-acquired-weakness
#15
Nicola Latronico, Margaret Herridge, Ramona O Hopkins, Derek Angus, Nicholas Hart, Greet Hermans, Theodore Iwashyna, Yaseen Arabi, Giuseppe Citerio, E Wesley Ely, Jesse Hall, Sangeeta Mehta, Kathleen Puntillo, Johannes Van den Hoeven, Hannah Wunsch, Deborah Cook, Claudia Dos Santos, Gordon Rubenfeld, Jean-Louis Vincent, Greet Van den Berghe, Elie Azoulay, Dale M Needham
We present areas of uncertainty concerning intensive care unit-acquired weakness (ICUAW) and identify areas for future research. Age, pre-ICU functional and cognitive state, concurrent illness, frailty, and health trajectories impact outcomes and should be assessed to stratify patients. In the ICU, early assessment of limb and diaphragm muscle strength and function using nonvolitional tests may be useful, but comparison with established methods of global and specific muscle strength and physical function and determination of their reliability and normal values would be important to advance these techniques...
March 13, 2017: Intensive Care Medicine
https://www.readbyqxmd.com/read/28231030/safety-of-patient-mobilization-and-rehabilitation-in-the-intensive-care-unit-systematic-review-with-meta-analysis
#16
Peter Nydahl, Thiti Sricharoenchai, Saurabh Chandra, Firuzan Sari Kundt, Minxuan Huang, Magdalena Fischill, Dale M Needham
BACKGROUND: Early mobilization and rehabilitation of patients in intensive care units (ICUs) may improve physical function, and reduce the duration of delirium, mechanical ventilation, and ICU length of stay. However, safety concerns are an important barrier to widespread implementation. OBJECTIVES: To synthesize safety data regarding patient mobilization and rehabilitation in the ICU, including falls, removal of endotracheal tubes, removal or dysfunction of intravascular catheters, removal of other catheters/tubes, cardiac arrest, hemodynamic changes, and desaturation...
May 2017: Annals of the American Thoracic Society
https://www.readbyqxmd.com/read/28219336/participant-retention-practices-in-longitudinal-clinical-research-studies-with-high-retention-rates
#17
Martha Abshire, Victor D Dinglas, Maan Isabella A Cajita, Michelle N Eakin, Dale M Needham, Cheryl Dennison Himmelfarb
BACKGROUND: There is a need for improving cohort retention in longitudinal studies. Our objective was to identify cohort retention strategies and implementation approaches used in studies with high retention rates. METHODS: Longitudinal studies with ≥200 participants, ≥80% retention rates over ≥1 year of follow-up were queried from an Institutional Review Board database at a large research-intensive U.S. university; additional studies were identified through networking...
February 20, 2017: BMC Medical Research Methodology
https://www.readbyqxmd.com/read/28204767/core-domains-in-evaluating-patient-outcomes-after-acute-respiratory-failure-international-multidisciplinary-clinician-consultation
#18
Carol L Hodgson, Alison E Turnbull, Theodore J Iwashyna, Ann Parker, Wesley Davis, Clifton O Bingham, Nicola R Watts, Simon Finfer, Dale M Needham
No abstract text is available yet for this article.
February 1, 2017: Physical Therapy
https://www.readbyqxmd.com/read/28108621/are-physical-measures-related-to-patient-centred-outcomes-in-ards-survivors
#19
Kitty S Chan, Lisa Aronson Friedman, Victor D Dinglas, Catherine L Hough, Carl Shanholtz, E Wesley Ely, Peter E Morris, Pedro A Mendez-Tellez, James C Jackson, Ramona O Hopkins, Dale M Needham
OBJECTIVE: To inform selection of physical measures for studies of acute respiratory distress syndrome (ARDS) survivors within 12 months of ARDS. METHODS: Secondary analysis of data from 6-month survivors participating in a US multicentre prospective study (ARDSNet Long-Term Outcome Study, N=134) or a multisite prospective study in Baltimore, Maryland, USA (Improving Care of Acute Lung Injury Patients, N=99). Physical measures, assessed at 6-month follow-up, were categorised according to the WHO's International Classification of Disability and Health: body functions and structures, activity and participation...
January 20, 2017: Thorax
https://www.readbyqxmd.com/read/28067712/muscle-weakness-and-5-year-survival-in-acute-respiratory-distress-syndrome-survivors
#20
MULTICENTER STUDY
Victor D Dinglas, Lisa Aronson Friedman, Elizabeth Colantuoni, Pedro A Mendez-Tellez, Carl B Shanholtz, Nancy D Ciesla, Peter J Pronovost, Dale M Needham
OBJECTIVES: To longitudinally evaluate the association of post-ICU muscle weakness and associated trajectories of weakness over time with 5-year survival. DESIGN: Longitudinal prospective cohort study over 5 years of follow-up. SETTING: Thirteen ICUs in four hospitals in Baltimore, MD. PATIENTS: One hundred fifty-six acute respiratory distress syndrome survivors. INTERVENTIONS: None. MEASUREMENTS AND MAIN RESULTS: Strength was evaluated with standardized manual muscle testing using the Medical Research Council sum score (range, 0-60; higher is better), with post-ICU weakness defined as sum score less than 48...
March 2017: Critical Care Medicine
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