Geert Spierenburg, Eric L Staals, Emanuela Palmerini, Robert Lor Randall, Steven W Thorpe, Jay S Wunder, Peter C Ferguson, Floortje G M Verspoor, Matthew T Houdek, Nicholas M Bernthal, Bart H W B Schreuder, Hans Gelderblom, Michiel A J van de Sande, Lizz van der Heijden
BACKGROUND: Diffuse-type tenosynovial giant cell tumor (D-TGCT) is a mono-articular, soft-tissue tumor. Although it can behave locally aggressively, D-TGCT is a non-malignant disease. This is the first study describing the natural course of D-TGCT and evaluating active surveillance as possible treatment strategy. METHODS: This retrospective, multicenter study included therapy naïve patients with D-TGCT from eight sarcoma centers worldwide between 2000 and 2019...
January 6, 2024: European Journal of Surgical Oncology