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https://www.readbyqxmd.com/read/28811317/sleep-duration-and-risk-of-type-2-diabetes
#1
Alicja R Rudnicka, Claire M Nightingale, Angela S Donin, Naveed Sattar, Derek G Cook, Peter H Whincup, Christopher G Owen
BACKGROUND: Associations between sleep duration and type 2 diabetes (T2D) risk markers in childhood have been little studied. We examined associations between self-reported sleep duration and T2D risk markers in children. METHODS: Cross-sectional study of 4525 multiethnic UK children aged 9 to 10 years. Sleep time was calculated from self-reported usual time of going to bed and getting up on a school day, validated in a subset using accelerometers. Fasting blood samples provided levels of serum lipids and insulin, plasma glucose, and HbA1c...
August 15, 2017: Pediatrics
https://www.readbyqxmd.com/read/28810682/effects-of-known-determinants-on-methylene-bisphenyl-isocyanate-mdi-concentration-during-spray-on-truck-bed-lining-processes
#2
Nicholas C Schaal, William J Brazile, Katie L Finnie, James P Tiger
Background: Occupational exposure to methylene bisphenyl isocyanate (MDI) presents serious worker health concerns as it may lead to short- and long-term health effects such as asthma, airway irritation, hypersensitivity pneumonitis, and irritation of skin and mucous membranes. While studies of worker isocyanate exposures during vehicle painting activities are widespread, few studies have investigated the spray-on truck bed-liner (STBL) industry. The purpose of this study was to determine the effectiveness of several ventilation system variables and process characteristics in controlling MDI concentrations in the STBL industry...
August 1, 2017: Annals of Work Exposures and Health
https://www.readbyqxmd.com/read/28806464/beyond-back-to-sleep-ways-to-further-reduce-the-risk-of-sudden-infant-death-syndrome
#3
Fern R Hauck, Kawai O Tanabe
Sudden infant death syndrome (SIDS) remains the leading cause of postneonatal mortality in the United States, despite reduction in rates of more than 50% since the initiation of the "Back to Sleep" (now called "Safe to Sleep") campaign in 1994. In recent years, the rate of decline in SIDS deaths has plateaued, even with the ongoing educational efforts that promote safe sleep and other risk reduction measures. The 2016 American Academy of Pediatrics guidelines for reducing the risk of SIDS focus heavily on sleep practices, bedding, and location, but also include factors that often receive less attention (ie, prenatal care, maternal smoking, alcohol and drug use, and childhood vaccinations)...
August 1, 2017: Pediatric Annals
https://www.readbyqxmd.com/read/28801698/association-between-dementia-and-reduced-walking-ability-and-30-day-mortality-in-patients-with-extended-spectrum-beta-lactamase-producing-escherichia-coli-bacteremia
#4
G Chapelet, A S Boureau, A Dylis, G Herbreteau, S Corvec, E Batard, G Berrut, L de Decker
Previous studies have shown controversial results of factors associated with short-term mortality in patients with extended-spectrum beta-lactamase (ESBL)-producing E. coli bacteremia and no research has investigated the impact of the geriatric assessment criteria on short-term mortality. Our objective was to determine whether dementia and walking ability are associated with 30-day mortality in patients with ESBL-producing E. coli bacteremia. All blood bottle cultures, analyzed from January 2008 to April 2015, in the Bacteriology Department of a 2,600-bed, university-affiliated center, Nantes, France, were retrospectively extracted...
August 12, 2017: European Journal of Clinical Microbiology & Infectious Diseases
https://www.readbyqxmd.com/read/28798032/improved-estrogen-receptor-assessment-by-pet-using-the-novel-radiotracer-4fmfes-in-er-breast-cancer-patients-an-ongoing-phase-ii-clinical-trial
#5
Michel Paquette, Éric Lavallée, Serge Phoenix, René Ouellet, Helena Senta, Johan E van Lier, Brigitte Guérin, Roger Lecomte, Éric E Turcotte
Following encouraging preclinical and human dosimetry results for the novel estrogen receptor (ER) positron emission tomography (PET) radiotracer 4-fluoro-11β-methoxy-16α-[(18)F]fluoroestradiol (4FMFES), a phase II clinical trial was initiated to compare the PET imaging diagnostic potential of 4FMFES to 16α-[(18)F]fluoroestradiol (FES) in ER positive (ER+) breast cancer patients. Methods: Patients diagnosed with ER+ breast cancer (n = 31) were recruited for this study, including six patients that undertook mastectomy and/or axillary node dissection...
August 10, 2017: Journal of Nuclear Medicine: Official Publication, Society of Nuclear Medicine
https://www.readbyqxmd.com/read/28795669/-evaluation-of-volume-overload-in-critical-patients-by-monitoring-change-of-cardiac-output-under-bed-head-raising-combined-with-passive-leg-raising
#6
Long Zhang, Luhao Wang, Weixiong Luo, Meihua Mei, Youjuan Chen, Bin Ouyang
OBJECTIVE: To investigate whether the change of cardiac output (CO) with bed head raising (BHR) combined with passive leg raising (PLR) can be used to assess volume overload in critical patients. METHODS: A prospective observational diagnostic trial was designed. The patients who underwent fluid resuscitation 6 hours or more, and admitted to intensive care unit (ICU) of Meizhou People's Hospital in Guangdong Province from January to December in 2016 were enrolled...
August 2017: Zhonghua Wei Zhong Bing Ji Jiu Yi Xue
https://www.readbyqxmd.com/read/28793935/utilization-of-electronic-health-record-events-to-conduct-a-tuberculosis-contact-investigation-in-a-high-risk-oncology-unit
#7
Shauna C Usiak, Fabian A Romero, Patrice Schwegman, Violet Fitzpatrick, MaryAnn Connor, Janet Eagan, Arthur E Brown, Mini Kamboj
OBJECTIVE To describe the utilization of electronic medical data resources, including health records and nursing scheduling resources, to conduct a tuberculosis (TB) exposure investigation in a high-risk oncology unit. SETTING A 42-bed inpatient unit with a mix of surgical and medical patients at a large tertiary-care cancer center in New York City. PARTICIPANTS High-risk subjects and coworkers exposed to a healthcare worker (HCW) with cavitary smear positive lung TB. RESULTS During the 3-month exposure period, 270 patients were admitted to the unit; 137 of these (50...
August 10, 2017: Infection Control and Hospital Epidemiology
https://www.readbyqxmd.com/read/28790896/a-quantitative-analysis-of-the-distribution-of-crh-neurons-in-whole-mouse-brain
#8
Jie Peng, Ben Long, Jing Yuan, Xue Peng, Hong Ni, Xiangning Li, Hui Gong, Qingming Luo, Anan Li
Corticotropin-releasing hormone (CRH), with widespread expression in the brain, plays a key role in modulating a series of behaviors, including anxiety, arousal, motor function, learning and memory. Previous studies have focused on some brain regions with densely distributed CRH neurons such as paraventricular hypothalamic nucleus (PVH) and bed nuclei of the stria terminalis (BST) and revealed some basic structural and functional knowledge of CRH neurons. However, there is no systematic analysis of brain-wide distribution of CRH neurons...
2017: Frontiers in Neuroanatomy
https://www.readbyqxmd.com/read/28780964/the-contexts-and-early-acheulean-archaeology-of-the-ef-hr-paleo-landscape-olduvai-gorge-tanzania
#9
Ignacio de la Torre, Rosa M Albert, Richard Macphail, Lindsay J McHenry, Michael C Pante, Ágata Rodríguez-Cintas, Ian G Stanistreet, Harald Stollhofen
Renewed fieldwork at the early Acheulean site of EF-HR (Olduvai Gorge, Tanzania) has included detailed stratigraphic studies of the sequence, extended excavations in the main site, and has placed eleven additional trenches within an area of nearly 1 km(2), to sample the same stratigraphic interval as in the main trench across the broader paleo-landscape. Our new stratigraphic work suggests that EF-HR is positioned higher in the Bed II sequence than previously proposed, which has implications for the age of the site and its stratigraphic correlation to other Olduvai Middle Bed II sites...
August 3, 2017: Journal of Human Evolution
https://www.readbyqxmd.com/read/28777415/repositioning-of-central-venous-access-devices-using-a-high-flow-flush-technique-a-clinical-practice-and-cost-review
#10
Timothy R Spencer
BACKGROUND: Malpositioned central venous access device (CVAD) tip locations can cause significant mechanical and chemical vessel-related injuries and complications if left in inappropriate positions.The aim of this study is to determine the use of a high-flow flush technique (HFFT) in successful correction of malpositioned catheters into the lower superior vena cava or cavoatrial junction and provide a cost comparison to interventional/fluoroscopic-based repositioning. METHODS: This is a Retrospective chart and radiographic review of all inserted CVADs found malpositioned between 1996-2014 in a multi-specialty 1000-bed tertiary trauma center in Sydney, Australia...
August 2, 2017: Journal of Vascular Access
https://www.readbyqxmd.com/read/28768499/simultaneous-primary-invasive-cutaneous-aspergillosis-in-two-preterm-twins-case-report-and-review-of-the-literature
#11
Floriane Gallais, Julie Denis, Olfa Koobar, Laurence Dillenseger, Dominique Astruc, Raoul Herbrecht, Ermanno Candolfi, Valérie Letscher-Bru, Marcela Sabou
BACKGROUND: Primary invasive cutaneous aspergillosis is a rare fungal infection that occurs mostly in immunocompromised patients. Newborns of very low birth weight present a high risk for this type of infection due to an immaturity of the cutaneous barrier and of the immune system. CASE PRESENTATION: We describe here a case of simultaneous invasive cutaneous aspergillosis in two preterm twins. Two male preterm bichorionic biamniotic twins (A & B) were born at a general hospital by spontaneous normal delivery at 24 weeks and 6 days of gestation...
August 2, 2017: BMC Infectious Diseases
https://www.readbyqxmd.com/read/28765133/balance-deficiencies-in-women-with-fibromyalgia-assessed-using-computerised-dynamic-posturography-a-cross-sectional-study-in-spain
#12
Marta Pérez-de-Heredia-Torres, Elisabet Huertas-Hoyas, Rosa Martínez-Piédrola, Domingo Palacios-Ceña, Jorge Alegre-Ayala, Montserrat Santamaría-Vázquez, César Fernández-de-Las-Peñas
OBJECTIVES: Our aims were (1) to compare the sensory organisation of balance control and balance strategies between women with fibromyalgia (FM) and healthy women; (2) to investigate which sensory component, that is, vestibular, visual or somato-sensory, is the most affected in FM and (3) to determine the associations between the functional independence measure (FIM) and balance responses in FM. DESIGN: Cross-sectional observational study. SETTING: Urban regional hospital and university (Universidad Rey Juan Carlos, Madrid, Spain)...
August 1, 2017: BMJ Open
https://www.readbyqxmd.com/read/28765106/the-level-of-provision-of-specialist-palliative-care-services-in-scotland-an-international-benchmarking-study
#13
Hamilton Inbadas, José Miguel Carrasco, Michelle Gillies, David Clark
OBJECTIVES: Comparative benchmarking of specialist palliative care (SPC) services across jurisdictions can be used to assess the adequacy of provision. Published in 2016, the Scottish Atlas of Palliative Care unlocks the possibility of benchmarking Scotland's provision against other European Union (EU) countries. Our objectives were to describe the provision of SPC services in Scotland and compare this with other EU countries, assessing coverage against European norms. METHODS: We conducted a secondary analysis of data collected as part for the Scottish Atlas by structured telephone (n=33) or online (n=3) survey with informants from 14 territorial health boards and 15 hospices who provided information about SPC services in their locality...
July 8, 2017: BMJ Supportive & Palliative Care
https://www.readbyqxmd.com/read/28764726/how-many-holes-is-too-many-a-prototype-tool-for-estimating-mosquito-entry-risk-into-damaged-bed-nets
#14
James Sutcliffe, Xin Ji, Shaoman Yin
BACKGROUND: Insecticide-treated bed nets (ITNs) have played an integral role in malaria reduction but how insecticide depletion and accumulating physical damage affect ITN performance is poorly understood. More accurate methods are needed to assess damage to bed nets so that they can be designed, deployed and replaced optimally. METHODS: Video recordings of female Anopheles gambiae in near approach (1-½ cm) to occupied untreated rectangular bed nets in a laboratory study were used to quantify the amount of mosquito activity (appearances over time) around different parts of the net, the per-appearance probability of a mosquito coming close to holes of different sizes (hole encounter) and the per-encounter probability of mosquitoes passing through holes of different sizes (hole passage)...
August 1, 2017: Malaria Journal
https://www.readbyqxmd.com/read/28764270/feasibility-and-complications-of-spinal-anaesthesia-in-percutaneous-nephrolithotomy-our-experience
#15
Manoj Kamal, Pradeep Sharma, Geeta Singariya, Rajesh Jain
INTRODUCTION: Percutaneous Nephrolithotomy (PCNL) is the treatment modality used for the extraction of large renal stones, or multiple calculi or stones resistant to shock wave lithotripsy. The General Anaesthesia (GA) is the standard modality for PCNL. However, few studies conclude that Spinal Anaesthesia (SA) can be an alternative method of anaesthesia with similar incidence of complications. AIM: In our study we evaluated the feasibility of spinal anaesthesia in terms of intraoperative and postoperative results in patients undergoing PCNL...
June 2017: Journal of Clinical and Diagnostic Research: JCDR
https://www.readbyqxmd.com/read/28764107/membrane-fouling-mitigation-in-a-moving-bed-membrane-bioreactor-combined-with-anoxic-biofilter-for-treatment-of-saline-wastewater-from-mariculture
#16
Weilong Song, Hong You, Zhipeng Li, Feng Liu, Peishi Qi, Fang Wang, Yizhu Li
Membrane fouling mitigation in a novel AF-MBMBR system (moving bed membrane bioreactor (10L) coupled with anoxic biofilter (4L)) under high salinity condition (35‰) was systematically investigated. Pre-positioned AF served as a pretreatment induced significant decrease of suspended biomass by 85% and dissolved organic matters by 51.7% in subsequent MBR, which resulted in a reduction of cake layer formation. Based on this, sponge bio-carriers in MBMBR further alleviated the fouling propensity by modifying extracellular polymeric substances (EPS) properties...
July 18, 2017: Bioresource Technology
https://www.readbyqxmd.com/read/28758823/physical-inactivity-and-platelet-function-in-humans-and-brown-bears-a-comparative-study
#17
K Arinell, S Blanc, K G Welinder, O-G Støen, A L Evans, O Fröbert
Physical inactivity increases the risk of thromboembolism. However, good standardized human models on inactivity are in short supply and experimental models are few. Our objective was to investigate how standardized bed rest affects platelet aggregation in humans and to investigate if aggregation is altered in a translational model system - the hibernating brown bear (Ursus arctos). We collected blood from (1) healthy male volunteers participating in a 21-day bed rest study in head-down tilt position (-6°) 24 h a day; (2) free-ranging brown bears captured during winter hibernation and again during active state in summer...
July 31, 2017: Platelets
https://www.readbyqxmd.com/read/28757691/cut-and-place-technique-of-pterygium-excision-with-autograft-without-using-sutures-or-glue-our-experience
#18
Jagdish Bhatia, Mathew Varghese, Bindu Narayanadas, Arti Bhatia
BACKGROUND: Conjunctival sutures used in pterygium surgery are not only time-consuming process but also may lead to local complications such as discomfort, scarring, granuloma, or infection. Plasma-derived products such as fibrin glue may produce possible hypersensitivity reactions whereas the risk of viral transmission remains theoretically possible. We describe a simple method of achieving conjunctival autograft adherence during pterygium surgery avoiding potential complications associated with the use of fibrin glue or sutures...
May 2017: Oman Journal of Ophthalmology
https://www.readbyqxmd.com/read/28754857/enhanced-radiosensitizing-by-sodium-glycididazole-in-a-recurrent-esophageal-carcinoma-tumor-model
#19
Peipei Wu, Jing Liu, Xiaorong Sun, Xiaolin Li, Ligang Xing, Jinming Yu
Re-irradiation is challenging for esophageal cancer patients with local-regional recurrence after initial radiotherapy. The purpose of this study is to establish a recurrent esophageal tumor model and investigate radiosensitizing effects of sodium glycididazole (CMNa). Tumor models were established by pre-irradiation (0 Gy, 10 Gy or 20 Gy) to the right hind leg of the nude mice 24 hours before tumor transplantation (ECA109 human esophageal carcinoma cells). Tumor growth curves were analyzed. Hypoxic microenvironment was exhibited in tumor frozen slides stained for pimonidazole, Hoechst 33342, hematoxylin-eosin and CD34...
July 10, 2017: Oncotarget
https://www.readbyqxmd.com/read/28753806/-68-ga-labeled-prostate-specific-membrane-antigen-ligand-positron-emission-tomography-computed-tomography-for-prostate-cancer-a-systematic-review-and-meta-analysis
#20
REVIEW
Finn E von Eyben, Maria Picchio, Rie von Eyben, Handoo Rhee, Glenn Bauman
CONTEXT: (68)Gallium prostate-specific membrane antigen (PSMA) ligand (68)Ga-HBED-CC-PSMA ((68)Ga-PSMA) is a promising radiotracer for positron emission tomography (PET)/computed tomography (CT) of prostate cancer. OBJECTIVE: To conduct a meta-analysis to evaluate detection rate, diagnostic test accuracy, and adverse effects of (68)Ga-PSMA PET/CT or PET/magnetic resonance imaging (MRI) for staging of prostate cancer and for restaging of rising prostate-specific antigen (PSA) after initial treatment...
November 15, 2016: European Urology Focus
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