keyword
MENU ▼
Read by QxMD icon Read
search

Decision aid

keyword
https://www.readbyqxmd.com/read/29667359/predicting-responses-to-mechanical-ventilation-for-preterm-infants-with-acute-respiratory-illness-using-artificial-neural-networks
#1
Katharine Brigham, Samir Gupta, John C Brigham
Infants born prematurely are particularly susceptible to respiratory illness due to underdeveloped lungs, which can often result in fatality. Preterm infants in acute stages of respiratory illness typically require mechanical ventilation assistance, and the efficacy of the type of mechanical ventilation and its delivery has been the subject of a number clinical studies. With recent advances in machine learning approaches, particularly deep learning, it may be possible to estimate future responses to mechanical ventilation in real-time, based on ventilation monitoring up to the point of analysis...
April 17, 2018: International Journal for Numerical Methods in Biomedical Engineering
https://www.readbyqxmd.com/read/29666787/cardiac-output-monitoring-in-preterm-infants
#2
REVIEW
Matthew McGovern, Jan Miletin
Maintaining optimal circulatory status is a key component of preterm neonatal care. Low-cardiac output (CO) in the preterm neonate leads to inadequate perfusion of vital organs and has been linked to a variety of adverse outcomes with heightened acute morbidity and mortality and adverse neurodevelopmental outcomes. Having technology available to monitor CO allows us to detect low-output states and potentially intervene to mitigate the unwanted effects of reduced organ perfusion. There are many technologies available for the monitoring of CO in the preterm neonatal population and while many act as useful adjuncts to aid clinical decision-making no technique is perfect...
2018: Frontiers in Pediatrics
https://www.readbyqxmd.com/read/29665552/emission-of-volatile-organic-compounds-from-plants-shows-a-biphasic-pattern-within-an-hormetic-context
#3
Evgenios Agathokleous, Mitsutoshi Kitao, Edward J Calabrese
Biogenic volatile organic compounds (BVOCs) are released to the atmosphere from vegetation. BVOCs aid in maintaining ecosystem sustainability via a series of functions, however, VOCs can alter tropospheric photochemistry and negatively affect biological organisms at high concentrations. Due to their critical role in ecosystem and environmental sustainability, BVOCs receive particular attention by global change biologists. To understand how plant VOC emissions affect stress responses within a dose-response context, dose responses should be evaluated...
April 14, 2018: Environmental Pollution
https://www.readbyqxmd.com/read/29665288/dilute-russel-viper-venom-time-analysis-in-a-haematology-laboratory-an-audit
#4
W Kruger, P W A Meyer, J G Nel
INTRODUCTION: To determine whether the current set of evaluation criteria used for dilute Russel Viper Venom Time (dRVVT) investigations in the routine laboratory meet expectation and identify possible shortcomings. METHODS: All dRVVT assays requested from January 2015 to December 2015 were appraised in this cross-sectional study. The raw data panels were compared with the new reference interval, established in 2016, to determine the sequence of assays that should have been performed...
April 17, 2018: International Journal of Laboratory Hematology
https://www.readbyqxmd.com/read/29665151/validation-of-the-pediatric-nexus-ii-head-ct-decision-instrument-for-selective-imaging-of-pediatric-patients-with-blunt-head-trauma
#5
Malkeet Gupta, William R Mower, Robert M Rodriguez, Gregory W Hendey
BACKGROUND: Data suggests that clinicians, when evaluating pediatric patients with blunt head trauma, may be over-ordering head computed tomography. Prior decision instruments aimed at aiding clinicians in safely forgoing CTs may be paradoxically increasing CT utilization. This study evaluated a novel decision instrument that aims for high sensitivity while also improving specificity over prior instruments. METHODS: We conducted a planned secondary analysis of the NEXUS Head CT decision instrument (DI) among patients less than 18 years old...
April 17, 2018: Academic Emergency Medicine: Official Journal of the Society for Academic Emergency Medicine
https://www.readbyqxmd.com/read/29664179/developing-and-pilot-testing-a-shared-decision-making-intervention-for-dialysis-choice
#6
Jeanette Finderup, Jens K D Jensen, Kirsten Lomborg
BACKGROUND: Evidence is inconclusive on how best to guide the patient in decision-making around haemodialysis and peritoneal dialysis choice. International guidelines recommend involvement of the patient in the decision to choose the dialysis modality most suitable for the individual patient. Nevertheless, studies have shown lack of involvement of the patient in decision-making. OBJECTIVES: To develop and pilot test an intervention for shared decision-making targeting the choice of dialysis modality...
April 17, 2018: Journal of Renal Care
https://www.readbyqxmd.com/read/29663250/fluid-filled-versus-gas-filled-intragastric-balloons-as-obesity-interventions-a-network-meta-analysis-of-randomized-trials
#7
Fateh Bazerbachi, Samir Haffar, Tarek Sawas, Eric J Vargas, Ravinder Jeet Kaur, Zhen Wang, Larry J Prokop, M Hassan Murad, Barham K Abu Dayyeh
BACKGROUND: Four commercially available intragastric balloons have been used for the management of obesity and underwent randomized controlled trials (RCTs), and we aimed to compare them using a network meta-analysis approach. METHODS: Several databases were queried from inception to May 26, 2017, and we included RCTs enrolling patients treated with Orbera, Heliosphere, ReShape Duo, and Obalon compared with another balloon, sham, or open-label control group. Two investigators independently abstracted data...
April 16, 2018: Obesity Surgery
https://www.readbyqxmd.com/read/29663054/field-evaluation-of-three-sources-of-genetic-resistance-to-sudden-death-syndrome-of-soybean
#8
Lillian F Brzostowski, Timothy I Pruski, Glen L Hartman, Jason P Bond, Dechun Wang, Silvia R Cianzio, Brian W Diers
Despite numerous challenges, field testing of three sources of genetic resistance to sudden death syndrome of soybean provides information to more effectively improve resistance to this disease in cultivars. Sudden death syndrome (SDS) of soybean [Glycine max (L.) Merrill] is a disease that causes yield loss in soybean growing regions across the USA and worldwide. While several quantitative trait loci (QTL) for SDS resistance have been mapped, studies to further evaluate these QTL are limited. The objective of our research was to map SDS resistance QTL and to test the effect of mapped resistance QTL on foliar symptoms when incorporated into elite soybean backgrounds...
April 16, 2018: TAG. Theoretical and Applied Genetics. Theoretische und Angewandte Genetik
https://www.readbyqxmd.com/read/29659341/impediments-to-effective-altruism-the-role-of-subjective-preferences-in-charitable-giving
#9
Jonathan Z Berman, Alixandra Barasch, Emma E Levine, Deborah A Small
Charity could do the most good if every dollar donated went to causes that produced the greatest welfare gains. In line with this proposition, the effective-altruism movement seeks to provide individuals with information regarding the effectiveness of charities in hopes that they will contribute to organizations that maximize the social return of their donation. In this research, we investigated the extent to which presenting effectiveness information leads people to choose more effective charities. We found that even when effectiveness information is made easily comparable across options, it has a limited impact on choice...
April 1, 2018: Psychological Science
https://www.readbyqxmd.com/read/29659067/computer-aided-diagnosis-of-prostate-cancer-using-a-deep-convolutional-neural-network-from-multiparametric-mri
#10
Yang Song, Yu-Dong Zhang, Xu Yan, Hui Liu, Minxiong Zhou, Bingwen Hu, Guang Yang
BACKGROUND: Deep learning is the most promising methodology for automatic computer-aided diagnosis of prostate cancer (PCa) with multiparametric MRI (mp-MRI). PURPOSE: To develop an automatic approach based on deep convolutional neural network (DCNN) to classify PCa and noncancerous tissues (NC) with mp-MRI. STUDY TYPE: Retrospective. SUBJECTS: In all, 195 patients with localized PCa were collected from a PROSTATEx database...
April 16, 2018: Journal of Magnetic Resonance Imaging: JMRI
https://www.readbyqxmd.com/read/29657202/outcomes-of-immunosuppression-in-iga-nephropathy-based-on-the-oxford-classification
#11
Dharmenaan Palamuthusingam, Clare Castledine, Sarah Lawman
Numerous studies have addressed the predictive value of pathology findings from the Oxford Classification. Whether this influences treatment choice has not been determined. We evaluated patients with IgA nephropathy who were immunosuppressed and correlated our findings with both clinical and histological features as per the Oxford Classification. This was a retrospective observational study of 45 patients who had biopsy-proven IgA nephropathy with a mean follow-up of 2.6 years. Primary outcomes were time to end-stage renal disease (ESRD) or a 50% rise in serum creatinine...
March 2018: Saudi Journal of Kidney Diseases and Transplantation
https://www.readbyqxmd.com/read/29656722/toward-a-contingency-model-for-hospital-based-health-technology-assessment-evidence-from-adhophta-project
#12
Americo Cicchetti, Valentina Iacopino, Silvia Coretti, Alessandra Fiore, Marco Marchetti, Laura Sampietro-Colom, Kristian Kidholm, Jean-Blaise Wasserfallen, Rabia Kahveci, Esa Halmesmäki, Magdalene Rosenmöller, Claudia Wild, Raul-Allan Kivet
OBJECTIVES: Hospital-based health technology assessment (HB-HTA) is becoming increasingly relevant because of its role in managing the introduction and withdrawal of health technologies. The organizational arrangement in which HB-HTA activities are conducted depends on several contextual factors, although the dominant models have several similarities. The aims of this study were to explore, describe, interpret, and explain seven cases of the application of HB-HTA logic and to propose a classification for HB-HTA organizational models which may be beneficial for policy makers and HTA professionals...
April 16, 2018: International Journal of Technology Assessment in Health Care
https://www.readbyqxmd.com/read/29655996/a-genomic-clinicopathologic-nomogram-for-the-preoperative-prediction-of-lymph-node-metastasis-in-bladder-cancer
#13
Shao-Xu Wu, Jian Huang, Zhuo-Wei Liu, Hai-Ge Chen, Pi Guo, Qing-Qing Cai, Jun-Jiong Zheng, Hai-De Qin, Zao-Song Zheng, Xin Chen, Rui-Yun Zhang, Si-Liang Chen, Tian-Xin Lin
Preoperative lymph node (LN) status is important for the treatment of bladder cancer (BCa). Here, we report a genomic-clinicopathologic nomogram for preoperatively predicting LN metastasis in BCa. In the discovery stage, 325 BCa patients from TCGA were involved and LN-status-related mRNAs were selected. In the training stage, multivariate logistic regression analysis was used to developed a genomic-clinicopathologic nomogram for preoperative LN metastasis prediction in the training set (SYSMH set, n=178). In the validation stage, we validated the nomogram using two independent sample sets (SYSUCC set, n=142; RJH set, n=104) with respect to its discrimination, calibration and clinical usefulness...
March 31, 2018: EBioMedicine
https://www.readbyqxmd.com/read/29652252/on-the-application-of-the-expected-log-likelihood-gain-to-decision-making-in-molecular-replacement
#14
Robert D Oeffner, Pavel V Afonine, Claudia Millán, Massimo Sammito, Isabel Usón, Randy J Read, Airlie J McCoy
Molecular-replacement phasing of macromolecular crystal structures is often fast, but if a molecular-replacement solution is not immediately obtained the crystallographer must judge whether to pursue molecular replacement or to attempt experimental phasing as the quickest path to structure solution. The introduction of the expected log-likelihood gain [eLLG; McCoy et al. (2017), Proc. Natl Acad. Sci. USA, 114, 3637-3641] has given the crystallographer a powerful new tool to aid in making this decision. The eLLG is the log-likelihood gain on intensity [LLGI; Read & McCoy (2016), Acta Cryst...
April 1, 2018: Acta Crystallographica. Section D, Structural Biology
https://www.readbyqxmd.com/read/29651521/-spondylotic-cervical-myelopathy-indication-of-surgical-treatment
#15
REVIEW
W Pepke, H Almansour, M Richter, M Akbar
BACKGROUND: The pathogenesis of cervical spondylotic myelopathy (CSM) is often multifactorial. Hence, the treatment of this disease requires a differentiated surgical approach in order to adequately address the underlying pathology. PURPOSE: The aim of this review is to identify factors that influence the choice of treatment strategy and to summarize them in an algorithm that serves as a decision aid in choosing the optimal indication for surgical treatment. An attempt is made to define the threshold values for the indication of surgical treatment and to discuss the ideal timing for performing surgery...
April 12, 2018: Der Orthopäde
https://www.readbyqxmd.com/read/29650602/primary-care-of-adults-with-intellectual-and-developmental-disabilities-2018-canadian-consensus-guidelines
#16
William F Sullivan, Heidi Diepstra, John Heng, Shara Ally, Elspeth Bradley, Ian Casson, Brian Hennen, Maureen Kelly, Marika Korossy, Karen McNeil, Dara Abells, Khush Amaria, Kerry Boyd, Meg Gemmill, Elizabeth Grier, Natalie Kennie-Kaulbach, Mackenzie Ketchell, Jessica Ladouceur, Amanda Lepp, Yona Lunsky, Shirley McMillan, Ullanda Niel, Samantha Sacks, Sarah Shea, Katherine Stringer, Kyle Sue, Sandra Witherbee
OBJECTIVE: To update the 2011 Canadian guidelines for primary care of adults with intellectual and developmental disabilities (IDD). METHODS: Family physicians and other health professionals experienced in the care of people with IDD reviewed and synthesized recent empirical, ecosystem, expert, and experiential knowledge. A system was developed to grade the strength of recommendations. RECOMMENDATIONS: Adults with IDD are a heterogeneous group of patients and have health conditions and factors affecting their health that can vary in kind, manifestation, severity, or complexity from those of others in the community...
April 2018: Canadian Family Physician Médecin de Famille Canadien
https://www.readbyqxmd.com/read/29650315/radiomics-based-features-for-pattern-recognition-of-lung-cancer-histopathology-and-metastases
#17
José Raniery Ferreira Junior, Marcel Koenigkam-Santos, Federico Enrique Garcia Cipriano, Alexandre Todorovic Fabro, Paulo Mazzoncini de Azevedo-Marques
BACKGROUND AND OBJECTIVES: lung cancer is the leading cause of cancer-related deaths in the world, and its poor prognosis varies markedly according to tumor staging. Computed tomography (CT) is the imaging modality of choice for lung cancer evaluation, being used for diagnosis and clinical staging. Besides tumor stage, other features, like histopathological subtype, can also add prognostic information. In this work, radiomics-based CT features were used to predict lung cancer histopathology and metastases using machine learning models...
June 2018: Computer Methods and Programs in Biomedicine
https://www.readbyqxmd.com/read/29649241/discovery-of-urinary-biomarkers-to-discriminate-between-exogenous-and-semi-endogenous-thiouracil-in-cattle-a-parallel-like-randomized-design
#18
Lieven Van Meulebroek, Jella Wauters, Beata Pomian, Julie Vanden Bussche, Philippe Delahaut, Eric Fichant, Lynn Vanhaecke
In the European Union, the use of thyreostats for animal fattening purposes has been banned and monitoring plans have been established to detect potential abuse. However, this is not always straightforward as thyreostats such as thiouracil may also have a semi-endogenous origin. Therefore, this study aimed at defining urinary metabolites, which may aid in defining the origin of detected thiouracil. Hereto, a parallel-like randomized in vivo study was conducted in which calves (n = 8) and cows (n = 8) were subjected to either a control treatment, rapeseed-enriched diet to induce semi-endogenous formation, or thiouracil treatment...
2018: PloS One
https://www.readbyqxmd.com/read/29649184/immunopathological-characterization-of-muscle-biopsy-samples-from-immune-mediated-necrotizing-myopathy-patients
#19
Qiong Wang, Yue Li, Suqiong Ji, Fang Feng, Bitao Bu
BACKGROUND Immune-mediated necrotizing myopathy (IMNM) is a relatively new proposed category of idiopathic inflammatory myopathies (IIMs), characterized by the presence of abundant necrotic muscle fibers, myophagocytosis, and sparse inflammatory infiltrates. The aim of our study was to analyze the immunopathological characteristics of IMNM by detecting biopsy samples from a cohort of patients, and to delineate the pathways involved in the pathogenesis. MATERIAL AND METHODS A retrospective evaluation of muscle biopsy samples, clinical and laboratory data, and immunohistochemical analysis of macrophages MHC-I and MAC, was performed for all patients diagnosed as having IMNM but without a prior exposure to statins...
April 12, 2018: Medical Science Monitor: International Medical Journal of Experimental and Clinical Research
https://www.readbyqxmd.com/read/29649079/in-search-of-mobile-applications-for-urogynecology-providers
#20
Shannon L Wallace, Shailja Mehta, Sara Farag, Robert S Kelley, Katherine T Chen
INTRODUCTION: Thousands of medical applications (apps) are available for mobile devices. Finding accurate, health care provider-centered apps may be time consuming and frustrating for urogynecologists. The objective of this study was to identify and evaluate urogynecology (urogyn) apps using a modified APPLICATIONS scoring system. MATERIALS AND METHODS: Urogyn apps were identified from the Apple iTunes and Google Play Stores using the following 10 MeSH terms: urogynecology, incontinence, prolapse, urinary tract infection, pelvic surgery, fecal incontinence, defecation disorder, voiding disorder, urethral diverticulum, and fistula...
April 11, 2018: Female Pelvic Medicine & Reconstructive Surgery
keyword
keyword
85847
1
2
Fetch more papers »
Fetching more papers... Fetching...
Read by QxMD. Sign in or create an account to discover new knowledge that matter to you.
Remove bar
Read by QxMD icon Read
×

Search Tips

Use Boolean operators: AND/OR

diabetic AND foot
diabetes OR diabetic

Exclude a word using the 'minus' sign

Virchow -triad

Use Parentheses

water AND (cup OR glass)

Add an asterisk (*) at end of a word to include word stems

Neuro* will search for Neurology, Neuroscientist, Neurological, and so on

Use quotes to search for an exact phrase

"primary prevention of cancer"
(heart or cardiac or cardio*) AND arrest -"American Heart Association"