keyword
MENU ▼
Read by QxMD icon Read
search

Infection in orthopedics

keyword
https://www.readbyqxmd.com/read/28223804/decreased-bacterial-growth-on-titanium-nanoscale-topographies-created-by-ion-beam-assisted-evaporation
#1
Michelle Stolzoff, Jason E Burns, Arash Aslani, Eric J Tobin, Congtin Nguyen, Nicholas De La Torre, Negar H Golshan, Katherine S Ziemer, Thomas J Webster
Titanium is one of the most widely used materials for orthopedic implants, yet it has exhibited significant complications in the short and long term, largely resulting from poor cell-material interactions. Among these many modes of failure, bacterial infection at the site of implantation has become a greater concern with the rise of antibiotic-resistant bacteria. Nanostructured surfaces have been found to prevent bacterial colonization on many surfaces, including nanotextured titanium. In many cases, specific nanoscale roughness values and resulting surface energies have been considered to be "bactericidal"; here, we explore the use of ion beam evaporation as a novel technique to create nanoscale topographical features that can reduce bacterial density...
2017: International Journal of Nanomedicine
https://www.readbyqxmd.com/read/28222919/specific-infectious-organisms-associated-with-poor-outcomes-in-treatment-for-hip-periprosthetic-infection
#2
Daniel J Cunningham, Joseph J Kavolus, Michael P Bolognesi, Samuel S Wellman, Thorsten M Seyler
BACKGROUND: Periprosthetic hip infection treatment remains a significant challenge for orthopedics. Some studies have suggested that methicillin resistance and gram-negative organism type are associated with increased treatment failure. The aim of this research is to determine if specific organisms were associated with poor outcomes in treatment for hip periprosthetic infection. METHODS: Records were reviewed of all patients between 2005 and 2015 who underwent treatment for infected partial or total hip arthroplasty...
January 26, 2017: Journal of Arthroplasty
https://www.readbyqxmd.com/read/28222067/designation-and-validation-of-a-posterior-anatomical-plate-for-the-anterior-column-of-the-acetabulum
#3
Lifeng Zhang, Chuangxin Lin, Shenglu Cao, Yiran Wang, Geng Peng, Yongqiang Xu, Yongzeng Feng, Gang Wang
BACKGROUND Surgical treatment of acetabular fractures is one of the greatest challenges for orthopedic surgeons. Fixation of most displaced fractures requires extensive exposure, which may lead to complications, including blood loss, neural or vascular injury, postoperative infection, wound healing problems, and heterotopic bone formation. MATERIAL AND METHODS This study was conducted to certify an anatomic plate with an anterior column lag screw guiding device to repair the posterior acetabulum. Complete pelvic spiral computed tomography (CT) scan data were collected from 56 patients...
February 21, 2017: Medical Science Monitor: International Medical Journal of Experimental and Clinical Research
https://www.readbyqxmd.com/read/28215487/executive-summary-of-management-of-prosthetic-joint-infections-clinical-practice-guidelines-by-the-spanish-society-of-infectious-diseases-and-clinical-microbiology-seimc
#4
Javier Ariza, Javier Cobo, Josu Baraia-Etxaburu, Natividad de Benito, Guillermo Bori, Javier Cabo, Pablo Corona, Jaime Esteban, Juan Pablo Horcajada, Jaime Lora-Tamayo, Oscar Murillo, Julián Palomino, Jorge Parra, Carlos Pigrau, José Luis Del Pozo, Melchor Riera, Dolores Rodríguez, Mar Sánchez-Somolinos, Alex Soriano, M Dolores Del Toro, Basilio de la Torre
The incidence of prosthetic joint infection (PJI) is expected to increase in the coming years. PJI has serious consequences for patients, and high costs for the health system. The complexity of these infections makes it necessary to organize the vast quantity of information published in the last several years. The indications for the choice of a given surgical strategy and the corresponding antimicrobial therapy are specifically reviewed. The authors selected clinically relevant questions and then reviewed the available literature in order to give recommendations according to a pre-determined level of scientific evidence...
February 16, 2017: Enfermedades Infecciosas y Microbiología Clínica
https://www.readbyqxmd.com/read/28214254/normothermia-in-arthroplasty
#5
REVIEW
Mark W Allen, David J Jacofsky
Since the initial design of surgical theaters, the thermal environment of the operating suite itself has been an area of concern and robust discussion. In the 1950s, correspondence in the British Medical Journal discussed the most suitable design for a surgeon's cap to prevent sweat from dripping onto the surgical field. These deliberations stimulated questions about the effects of sweat-provoking environments on the efficiency of the surgical team, not to mention the effects on the patient. Although these benefits translate to implant-based orthopedic surgery, they remain poorly understood and, at times, ignored...
January 17, 2017: Journal of Arthroplasty
https://www.readbyqxmd.com/read/28206933/use-of-antibiotic-impregnated-absorbable-beads-and-tissue-coverage-of-complex-wounds
#6
Terris L White, Alfred T Culliford, Martin Zomaya, Gary Freed, Christopher P Demas
The treatment of complex wounds is commonplace for plastic surgeons. Standard management is debridement of infected and devitalized tissue and systemic antibiotic therapy. In cases where vital structures are exposed within the wound, coverage is obtained with the use of vascularized tissue using both muscle and fasciocutaneous flaps. The use of nondissolving polymethylmethacrylate and absorbable antibiotic-impregnated beads has been shown to deliver high concentrations of antibiotics with low systemic levels of the same antibiotic...
November 1, 2016: American Surgeon
https://www.readbyqxmd.com/read/28195958/rehospitalization-in-the-first-year-following-veteran-and-service-member-tbi-a-va-tbi-model-systems-study
#7
Johanna Tran, Flora Hammond, Kristen Dams-OʼConnor, Xinyu Tang, Blessen Eapen, Marissa McCarthy, Risa Nakase-Richardson
OBJECTIVE: To determine the incidence and causes of rehospitalization following military or Veteran traumatic brain injury (TBI). SETTING: Department of Veterans Affairs (VA) Veterans Health Administration Polytrauma Rehabilitation Centers (VHA PRCs). PARTICIPANTS: Consecutive sample of VHA TBI Model System participants (N = 401). DESIGN: Prospective observational cohort study. MAIN MEASURES: Number and type of rehospitalizations in first year post-TBI...
February 10, 2017: Journal of Head Trauma Rehabilitation
https://www.readbyqxmd.com/read/28195606/use-of-articulating-spacer-technique-in-revision-total-knee-arthroplasty-complicated-by-sepsis-a-systematic-meta-analysis
#8
John C Spivey, George N Guild, Giles R Scuderi
Periprosthetic infection after total knee arthroplasty is a devastating complication, and 2-stage exchange is the standard of care in North America. Articulating spacers are effective in treating periprosthetic joint infections, but the optimal articulating spacer construct has yet to be identified. The authors performed a systematic review using MEDLINE, MEDLINE In-Process, EMBASE, BIOSIS, ClinicalTrials.gov, and Cochrane Database of Systematic Reviews. They identified 34 articles meeting inclusion criteria, producing 1016 spacers for comparison...
February 13, 2017: Orthopedics
https://www.readbyqxmd.com/read/28185243/staphylococcal-protein-a-promotes-osteoclastogenesis-through-mapk-signaling-during-bone-infection
#9
Yuan Wang, Xin Liu, Ce Dou, Zhen Cao, Chuan Liu, Shiwu Dong, Jun Fei
Bone infection is a common and serious complication in the orthopedics field, which often leads to excessive bone destruction and non-union. Osteoclast is the only type of cells which have the function of bone resorption. Its over activation is closely related to excessive bone loss. Staphylococcus aureus (S.aureus) is a major pathogen causing bone infection, which can produce a large number of strong pathogenic substances staphylococcal protein A (SPA). However, few studies were reported about the effects of SPA on osteoclastogenesis...
February 10, 2017: Journal of Cellular Physiology
https://www.readbyqxmd.com/read/28169939/precise-measurement-of-the-outer-diameters-of-antibiotic-laden-cement-nails-produced-by-various-sized-thoracostomy-catheter-molds
#10
Cory M Czajka, Ian N Bauer, Stephen J Warner, Robin N Goytia, Mark R Brinker
OBJECTIVES: At our institution, custom made antibiotic-laden cement nails fabricated during surgery using a thoracostomy catheter as a mold is commonly employed to treat long bone infection. As the outer diameter of the nails produced has not previously been described, we designed a study to measure the outer diameter of antibiotic-laden cement nails fashioned using commercially available and commonly utilized thoracostomy catheters of various sizes. METHODS: Six thoracostomy catheters from two different manufactures (Argyle™ PVC Thoracic Catheters, Covidien Ltd...
January 24, 2017: Journal of Orthopaedic Trauma
https://www.readbyqxmd.com/read/28166064/incidence-and-risk-factors-of-surgical-site-infections-in-kathmandu-university-hospital-kavre-nepal
#11
S Shrestha, P Wenju, R Shrestha, R M Karmacharya
Background Surgical site infections (SSI) are the common nosocomial infection in surgical patients, and are a significant source of postoperative morbidity resulting in increased hospital stay, morbidity and cost. Objective The objective of this study was to obtain the incidence of SSI and determine various risks factors influencing the SSI rate with special reference to the National Nosocomial Infections Surveillance System risk index in Kathmandu University Hospital, Kavre, Nepal. Method Six hundred and thirty eight patients who underwent various surgeries in Dhulikhel Hospital, Kathmandu University Hospital during a three-month period were included...
April 2016: Kathmandu University Medical Journal (KUMJ)
https://www.readbyqxmd.com/read/28159606/recent-coating-developments-for-combination-devices-in-orthopedic-and-dental-applications-a-literature-review
#12
Eric J Tobin
Orthopedic and dental implants have been used successfully for decades to replace or repair missing or damaged bones, joints, and teeth, thereby restoring patient function subsequent to disease or injury. However, although device success rates are generally high, patient outcomes are sometimes compromised due to device-related problems such as insufficient integration, local tissue inflammation, and infection. Many different types of surface coatings have been developed to address these shortcomings, including those that incorporate therapeutic agents to provide localized delivery to the surgical site...
January 31, 2017: Advanced Drug Delivery Reviews
https://www.readbyqxmd.com/read/28155060/fast-resorbable-antibiotic-loaded-hydrogel-coating-to-reduce-post-surgical-infection-after-internal-osteosynthesis-a-multicenter-randomized-controlled-trial
#13
Kostantinos Malizos, Michael Blauth, Adrian Danita, Nicola Capuano, Riccardo Mezzoprete, Nicola Logoluso, Lorenzo Drago, Carlo Luca Romanò
BACKGROUND: Infection is one of the main reasons for failure of orthopedic implants. Antibacterial coatings may prevent bacterial adhesion and biofilm formation, according to various preclinical studies. The aim of the present study is to report the first clinical trial on an antibiotic-loaded fast-resorbable hydrogel coating (Defensive Antibacterial Coating, DAC(®)) to prevent surgical site infection, in patients undergoing internal osteosynthesis for closed fractures. MATERIALS AND METHODS: In this multicenter randomized controlled prospective study, a total of 256 patients in five European orthopedic centers who were scheduled to receive osteosynthesis for a closed fracture, were randomly assigned to receive antibiotic-loaded DAC or to a control group (without coating)...
February 2, 2017: Journal of Orthopaedics and Traumatology: Official Journal of the Italian Society of Orthopaedics and Traumatology
https://www.readbyqxmd.com/read/28154812/qivas-therapy-for-treatment-of-implant-associated-mdr-bacterial-infection
#14
Varun Chouhan
INTRODUCTION: Orthopedic implant-associated infections are difficult to treat, both physically and psychologically, for the patient and the surgeon as well. Organisms capable of forming biofilms tend to be more virulent and have ability of causing chronic infections. Chronic implant associated infections are very difficult to treat, requires a lot of time, money and other resources. Chronic infections produce a lot of morbidity and sometimes mortality to the patient. CASE REPORT: A 40-year-old male treated for bilateral acetabular fracture sustained after fall from height due to an episode of seizure...
April 2016: Journal of Orthopaedic Case Reports
https://www.readbyqxmd.com/read/28141587/osteoarticular-and-soft-tissue-melioidosis-in-malaysia-clinical-characteristics-and-molecular-typing-of-the-causative-agent
#15
AbdelRahman Mohammad Zueter, Mahmoud Abumarzouq, Mohd Imran Yusof, Wan Faisham Wan Ismail, Azian Harun
INTRODUCTION: Melioidosis involving bone, joints, and soft tissue is rare and reported usually following dissemination of disease from infection elsewhere in the body; to a lesser degree, it can also be reported as the primary manifestation of melioidosis. METHODOLOGY: The orthopedic registry at Hospital University Sains Malaysia from 2008 until 2014 was retrospectively reviewed and was followed by molecular typing of Burkholderia pseudomallei. RESULTS: Out of 20 cases identified, 19 patients were confirmed to have osteoarticular and/or soft-tissue melioidosis...
January 30, 2017: Journal of Infection in Developing Countries
https://www.readbyqxmd.com/read/28137325/interhospital-comparison-of-surgical-site-infection-rates-in-orthopedic-surgery
#16
Jozica Skufca, Jukka Ollgren, Mikko J Virtanen, Kaisa Huotari, Outi Lyytikäinen
OBJECTIVE To investigate whether comparison by deep or adjusted deep surgical site infection (SSI) rates in orthopedic surgeries are a better basis for feedback to Finnish hospitals than overall SSI rates DESIGN Retrospective cohort study SETTING Hospitals conducting surveillance of hip arthroplasties (HPROs) and knee arthroplasties (KPROs) in the Finnish Hospital Infection Program METHODS We analyzed surveillance data for 73,227 HPROs and 56,860 KPROs performed in 18 hospitals during 1999-2014. For each hospital, the overall, deep, and adjusted deep SSI rates with 95% confidence intervals (CIs) were calculated, and the hospital ranks were simulated in the Bayesian framework...
January 31, 2017: Infection Control and Hospital Epidemiology
https://www.readbyqxmd.com/read/28135373/elution-profiles-of-two-methods-of-antibiotic-tibial-nail-preparations
#17
Matthew R Karek, Nancy M Jackson, Jeffrey C Flynn, Rahul Vaidya, David C Markel
Interlocking nails coated with antibiotic-supplemented cement provide effective treatment of infected long bone nonunion, but the thicker coating on guidewires may provide greater antibacterial activity. This study compared the properties of cement cured on each construct by evaluating 2-cm segments of 8-mm interlocking nails and 3.5-mm guidewires coated with antibiotic-supplemented cement. Each construct (n=7 for each group) was coated with polymethylmethacrylate cement (Simplex; Stryker Orthopaedics, Mahwah, New Jersey) containing either 1 g tobramycin or 1 g vancomycin powder plus 2...
January 30, 2017: Orthopedics
https://www.readbyqxmd.com/read/28133966/fabrication-of-antibacterial-and-antiwear-hydroxyapatite-coatings-via-in-situ-chitosan-mediated-pulse-electrochemical-deposition
#18
Ling Yan, Yi Xiang, Jia Yu, Yingbo Wang, Wenguo Cui
Although bioinert titanium has been widely applied in orthopedics and related fields, its usage is limited by its unsatisfying osteoinductivity, anti-infection capability, and wear-resistance. Osteoinductive apatite coating can be fabricated on a titanium surface by electrochemical methods, but this causes bacterial adhesion and poor wear-resistance. On the basis of pulse electrochemical technology, a wear-resistance and antibacterial osteoinductive coating was fabricated through codeposition of hydroxyapatite (HA) and nano-Ag effectuated by the cohybridization ofchitosan (CS) with Ag(+) and Ca(2+)...
January 30, 2017: ACS Applied Materials & Interfaces
https://www.readbyqxmd.com/read/28132729/malnutrition-an-underestimated-factor-in-the-inpatient-treatment-of-traumatology-and-orthopedic-patients-a-prospective-evaluation-of-1055-patients
#19
Christoph Ihle, Thomas Freude, Christian Bahrs, Eva Zehendner, Janick Braunsberger, Hans Konrad Biesalski, Christine Lambert, Ulrich Stöckle, Elke Wintermeyer, Julia Grünwald, Leonard Grünwald, Gunnar Ochs, Ingo Flesch, Andreas Nüssler
INTRODUCTION: Suboptimal nutritional status is often observed among hospitalized patients across all medical specialties. The objective of the present study was to (1) analyze the prevalence of malnutrition in hospitalized orthopedic and trauma patients and (2) to evaluate the relationship between malnutrition and selected clinical outcomes. MATERIALS AND METHODS: The prospective field study was conducted between 06/2014 and 06/2015 in a German level I trauma center (Department of Traumatology, Septic Trauma Surgery and Arthroplasty) with a total number of 1055 patients...
January 22, 2017: Injury
https://www.readbyqxmd.com/read/28130825/magnesium-alloy-az91-exhibits-antimicrobial-properties-in-vitro-but-not-in-vivo
#20
Emily K Brooks, Richard Ahn, Menachem E Tobias, Lisa A Hansen, Nicole R Luke-Marshall, Linda Wild, Anthony A Campagnari, Mark T Ehrensberger
Magnesium alloys hold great promise for developing orthopedic implants that are biocompatible, biodegradable, and mechanically similar to bone tissue. This study evaluated the in vitro and in vivo antimicrobial properties of magnesium-9%aluminum-1%zinc (AZ91) and commercially pure titanium (cpTi) against Acinetobacter baumannii (Ab307). The in vitro results showed that as compared to cpTi, incubation with AZ91 significantly reduced both the planktonic (cpTi = 3.45e8, AZ91 = 8.97e7, p < 0.001) colony forming units (CFU) and biofilm-associated (cpTi = 3...
January 27, 2017: Journal of Biomedical Materials Research. Part B, Applied Biomaterials
keyword
keyword
85842
1
2
Fetch more papers »
Fetching more papers... Fetching...
Read by QxMD. Sign in or create an account to discover new knowledge that matter to you.
Remove bar
Read by QxMD icon Read
×

Search Tips

Use Boolean operators: AND/OR

diabetic AND foot
diabetes OR diabetic

Exclude a word using the 'minus' sign

Virchow -triad

Use Parentheses

water AND (cup OR glass)

Add an asterisk (*) at end of a word to include word stems

Neuro* will search for Neurology, Neuroscientist, Neurological, and so on

Use quotes to search for an exact phrase

"primary prevention of cancer"
(heart or cardiac or cardio*) AND arrest -"American Heart Association"