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https://www.readbyqxmd.com/read/28056924/anti-arthritic-activity-of-ethanol-extract-of-claoxylon-indicum-on-freund-s-complete-adjuvant-induced-arthritis-in-mice
#1
Yong Chen, Qi-Wen Wang, Jian Zuo, Jian-Wei Chen, Xiang Li
BACKGROUND: Claoxylon indicum Hassk. (Euphorbiaceae), named Diu Le Bang, have functions of dehumidification and relieving swelling pain, and is used as a folk medicine to treat Rheumatoid arthritis (RA), lumbocrural pain and foot edema in the south of China. The aim of the present study was to investigate the anti-arthritic activity of the ethanol extract of Claoxylon indicum (CIE) on mice with adjuvant induced joint arthritis. METHODS: Adjuvant arthritis was induced in mice by subcutaneous injection of complete Freund's adjuvant into the plantar surface of right hind paw...
January 5, 2017: BMC Complementary and Alternative Medicine
https://www.readbyqxmd.com/read/28056277/-direct-medical-costs-and-influencing-factors-in-severe-hand-foot-and-mouth-disease-in-children-aged-between-six-months-and-five-years-old
#2
Y M Zheng, J Yang, Q H Liao
Objective: To estimate the direct medical cost of severe hand, foot and mouth disease (HFMD) in patients aged less than five years. Methods: A stratified sampling method was used to collect data on severe HFMD cases reported in the National HFMD surveillance database between Jan 1, 2012, and Dec 31, 2013. The sampling was referenced with the national aetiologic distribution of Enterovirus A71 (EV-A71), Coxsackievirus A16 (CV-A16) and other Enteroviruses (OEV) for severe HFMD cases and the included cases were distributed among seven geographic regions (Northeast, North China, Northwest, Central China, Southwest, East China and South China)...
January 6, 2017: Zhonghua Yu Fang Yi Xue za Zhi [Chinese Journal of Preventive Medicine]
https://www.readbyqxmd.com/read/28054925/the-wound-trend-scale-a-retrospective-review-of-utility-and-predictive-value-in-the-assessment-and-documentation-of-lower-leg-ulcers
#3
Noreen A Campbell, Donna L Campbell, Andrea Turner
Wound assessment is essential to manage wound care. The Wound Trend Scale (WTS) is a paper-and-pen instrument comprised of 14 parameters designed to guide assessment of findings relevant to lower leg ulcer management and includes an infection screen and cues for physician consultation. To determine its clinical utility, predictive value, and reliability, data were retrospectively analyzed from a random sampling of medical records of patients seen at a Foot and Leg Clinic between January 1, 2007 and December 31, 2008...
December 2016: Ostomy/wound Management
https://www.readbyqxmd.com/read/28010834/acupuncture-treatment-of-a-metatarsus-proximal-end-fracture-a-case-report
#4
Yılmaz Sezgin, Sinan Becel, Fatih Akçay
A tuberosity fracture is an avulsion fracture in an area 1.5 cm proximal to the fifth metatarsus. Six to eight weeks of immobilization may be required. A patient with a short leg plaster splint came to our clinic because of pain. The patient had a diagnosis of a fifth metatarsus fracture. Significant edema, fluctuation on the dorsolateral section of the left foot, and red color changes (0.2- to 0.3-cm diameter) on the skin of the anterolateral tibial area of the affected leg were noted. The locations of these skin changes corresponded to the GB34 (Yanglingguan) and the ST37 (Shanqiuxu) acupoints...
December 2016: Journal of Acupuncture and Meridian Studies
https://www.readbyqxmd.com/read/28005247/efficacy-and-safety-of-low-dose-capecitabine-plus-docetaxel-versus-single-agent-docetaxel-in-patients-with-anthracycline-pretreated-her2-negative-metastatic-breast-cancer-results-from-the-randomized-phase-iii-jo21095-trial
#5
Daigo Yamamoto, Nobuaki Sato, Yoshiaki Rai, Yutaka Yamamoto, Mitsue Saito, Hiroji Iwata, Norikazu Masuda, Shoji Oura, Junichiro Watanabe, Satoshi Hattori, Yoshimasa Matsuura, Katsumasa Kuroi
PURPOSE: The randomized phase III JO21095 trial compared the efficacy and safety of low-dose capecitabine plus docetaxel combination therapy (XT) versus single-agent administration of docetaxel in anthracycline-pretreated HER2-negative metastatic breast cancer. METHODS: Patients were randomized to either low-dose XT (capecitabine 825 mg/m(2) twice daily, days 1-14; docetaxel 60 mg/m(2), day 1 every 3 weeks) or docetaxel (70 mg/m(2), day 1 every 3 weeks). The primary objective was to demonstrate superior progression-free survival (PFS) with low-dose XT versus single-agent docetaxel...
February 2017: Breast Cancer Research and Treatment
https://www.readbyqxmd.com/read/28002322/the-effect-of-polydeoxyribonucleotide-prolotherapy-on-posterior-tibial-tendon-dysfunction-after-ankle-syndesmotic-surgery-a-case-report
#6
Tae-Ha Lim, Hyung Rae Cho, Keum Nae Kang, Chang Joon Rhyu, Sung Won Chon, Young Su Lim, Jee In Yoo, Jung-Won Kim, Young Uk Kim
RATIONALE: Ankle syndesmotic injuries occasionally require long-term therapy for recovery and can result in tendon injury. Posterior tibial tendon dysfunction (PTTD) is an acquired deformity that can cause flatfoot deformity. The current nonoperative management of PTTD includes nonsteroidal antiinflammatory drugs (NSAIDs), orthopedic devices. Although various treatment options have been attempted, optimal treatments for each stage of the condition are debated. Polydeoxyribonucleotide (PDRN) is effective in healing of chronic wounds associated with tissue damage by attracting tissue growth factors...
December 2016: Medicine (Baltimore)
https://www.readbyqxmd.com/read/27998302/immunoglobulin-g4-related-constrictive-pericarditis-identified-by-cytological-examination-of-pericardial-effusion-a-case-report
#7
Kazunori Horie, Norio Tada, Keiichirou Yamaguchi, Keitarou Inazawa, Mareyuki Endo, Naoto Inoue
BACKGROUND: Immunoglobulin G4-related disease is increasingly recognized as a systemic autoimmune disorder characterized by immunoglobulin G4-positive lymphocyte infiltration. Organ biopsy and histopathology are the most important diagnostic methods; however, the significance of a cytological examination in immunoglobulin G4-related disease cases is still unclear. CASE PRESENTATION: A 73-year-old Asian man who was a former tobacco smoker presented with progressive exertional dyspnea, systemic edema, and pericardial effusion...
December 20, 2016: Journal of Medical Case Reports
https://www.readbyqxmd.com/read/27940460/minimal-change-disease
#8
Marina Vivarelli, Laura Massella, Barbara Ruggiero, Francesco Emma
Minimal change disease (MCD) is a major cause of idiopathic nephrotic syndrome (NS), characterized by intense proteinuria leading to edema and intravascular volume depletion. In adults, it accounts for approximately 15% of patients with idiopathic NS, reaching a much higher percentage at younger ages, up to 70%-90% in children >1 year of age. In the pediatric setting, a renal biopsy is usually not performed if presentation is typical and the patient responds to therapy with oral prednisone at conventional doses...
December 9, 2016: Clinical Journal of the American Society of Nephrology: CJASN
https://www.readbyqxmd.com/read/27927089/an-evaluation-of-the-anti-inflammatory-antipyretic-and-analgesic-effects-of-hydroethanol-leaf-extract-of-albizia-zygia-in-animal-models
#9
Wonder Kofi Mensah Abotsi, Stanley Benjamin Lamptey, Stephen Afrane, Eric Boakye-Gyasi, Ruth Uwa Umoh, Eric Woode
CONTEXT: The leaves of Albizia zygia (DC.) J.F. Macbr. (Leguminosae-Mimosoideae) are used in Ghanaian traditional medicine for the treatment of pain, inflammatory disorders and fever (including malaria). OBJECTIVES: The present study evaluated the anti-inflammatory, antipyretic and analgesic effects of the hydroethanol leaf extract of Albizia zygia (AZE) in animal models. MATERIALS AND METHODS: The anti-inflammatory and antipyretic effects of AZE were examined in the carrageenan-induced foot oedema model and the baker's yeast-induced pyrexia test respectively...
December 2017: Pharmaceutical Biology
https://www.readbyqxmd.com/read/27826325/enterovirus-71-infection-and-neurological-complications
#10
REVIEW
Kyung Yeon Lee
Since the outbreak of the enterovirus 71 (EV71) infection in Malaysia in 1997, large epidemics of EV71 have occurred in the Asia-Pacific region. Many children and infants have died from serious neurological complications during these epidemics, and EV71 infection has become a serious public health problem in these areas. EV71 infection causes hand, foot and mouth disease (HFMD) in children, and usually resolves spontaneously. However, EV71 occasionally involves the central nervous system (CNS), and induces diverse neurological complications such as brainstem encephalitis, aseptic meningitis, and acute flaccid paralysis...
October 2016: Korean Journal of Pediatrics
https://www.readbyqxmd.com/read/27818360/n-terminal-pro-b-type-natriuretic-peptide-for-the-prognostic-prediction-of-severe-enterovirus-71-associated-hand-foot-and-mouth-disease
#11
Jun Qiu, Xiulan Lu, Pingping Liu, Xinping Zhang, Chao Zuo, Zhenghui Xiao
OBJECTIVE: The aim of this study was to determine whether N-terminal pro-B-type natriuretic peptide (NT-proBNP) can predict impending brainstem encephalitis, pulmonary edema, pulmonary hemorrhage, cardiopulmonary failure, and death in children with severe enterovirus 71 (EV71)-associated hand, foot, and mouth disease (HFMD). METHODS: Plasma NT-proBNP levels of 282 children with severe EV71-associated HFMD were measured. RESULTS: NT-proBNP levels were significantly higher in patients with elevated blood glucose (>7...
January 2017: International Journal of Infectious Diseases: IJID
https://www.readbyqxmd.com/read/27801415/-comparative-evaluation-of-the-intensity-of-reparative-processes-in-the-lower-extremity-soft-tissues-of-diabetic-patients-receiving-local-negative-pressure-wound-treatment-and-standard-wound-care
#12
G R Galstyan, A Yu Tokmakova, E L Zaitseva, L P Doronina, I A Voronkova, R V Molchkov
AIM: To study the intensity of soft tissue repair in patients with diabetic foot syndrome (DFS) during local negative pressure wound treatment versus standard wound care. SUBJECTS AND METHODS: The investigators estimated the clinical (wound sizes, local tissue oxygenation), histological (light microscopy), and immunohistochemical (CD31, CD68, MMP-9, and TIMP-1) markers for reparative processes in patients with DFS during vacuum therapy versus standard wound care...
2016: Terapevticheskiĭ Arkhiv
https://www.readbyqxmd.com/read/27770823/body-mass-index-and-extent-of-mri-detected-inflammation-opposite-effects-in-rheumatoid-arthritis-versus-other-arthritides-and-asymptomatic-persons
#13
Lukas Mangnus, Wouter P Nieuwenhuis, Hanna W van Steenbergen, Tom W J Huizinga, Monique Reijnierse, Annette H M van der Helm-van Mil
BACKGROUND: In the population a high body mass index (BMI) has been associated with slightly increased inflammatory markers. Within rheumatoid arthritis (RA), however, a high BMI has been associated with less radiographic progression; this phenomenon is unexplained. We hypothesized that the phenomenon is caused by an inverse relationship between BMI and inflammation in hand and foot joints with RA. To explore this hypothesis, local inflammation was measured using magnetic resonance imaging (MRI) in early arthritis patients presenting with RA or other arthritides and in asymptomatic volunteers...
October 22, 2016: Arthritis Research & Therapy
https://www.readbyqxmd.com/read/27706779/clinical-significance-of-combined-liver-function-and-high-sensitivity-c-reactive-protein-measurement-in-children-with-hand-foot-mouth-disease
#14
F X Han, J H Gao, J H Gai
Hand-foot-mouth disease (HFMD) is a common pediatric disease responsible for the development of rashes or herpes on the hand, foot, and mouth. Severe complications of HFMD include myocarditis, pulmonary edema, aseptic meningoencephalitis, and even death. Therefore, early diagnosis of HFMD is of particular importance. In this study, we determined the clinical value of the combined detection of liver function and high-sensitivity C-reactive protein (hs-CRP) expression in children with HFMD. Three hundred children with HFMD were recruited to this study between July 2013 and July 2015 and divided into the mild and severe HFMD groups (N = 150 per group)...
September 23, 2016: Genetics and Molecular Research: GMR
https://www.readbyqxmd.com/read/27690011/aquaporin-4-a-potential-therapeutic-target-for-cerebral-edema
#15
Guanghui Tang, Guo-Yuan Yang
Aquaporin-4 (AQP4) is a family member of water-channel proteins and is dominantly expressed in the foot process of glial cells surrounding capillaries. The predominant expression at the boundaries between cerebral parenchyma and major fluid compartments suggests the function of aquaporin-4 in water transfer into and out of the brain parenchyma. Accumulating evidences have suggested that the dysregulation of aquaporin-4 relates to the brain edema resulting from a variety of neuro-disorders, such as ischemic or hemorrhagic stroke, trauma, etc...
2016: International Journal of Molecular Sciences
https://www.readbyqxmd.com/read/27594952/intra-articular-osteoid-osteoma-of-the-calcaneus-a-case-report-and-review
#16
Tomo Hamada, Hidenori Matsubara, Hiroaki Kimura, Takao Aikawa, Yasuhisa Yoshida, Hiroyuki Tsuchiya
Osteoid osteoma of the calcaneus is rare and frequently misdiagnosed as arthritis because of similar symptoms. In addition, radiographic findings may be nonspecific, and magnetic resonance imaging (MRI) may show a bone marrow edema and changes in adjacent soft tissue. A 19-year-old man presented with a 6-month history of persistent pain and swelling in the left hind foot; diagnostic computed tomography and MRI analyses revealed lesions suggesting an intra-articular osteoid osteoma of the calcaneus. Initial MRI did not show specific findings...
September 2016: Radiology case reports
https://www.readbyqxmd.com/read/27594570/-skillful-care-for-chronic-vascular-wounds
#17
C Goullet de Rugy, I Lazareth, C You, A Stansal, P Priollet
In vascular medicine, wound care requires pluridisciplinary expertise and nursing skill. Care must be perfectly adapted to each individual patient, the specificities of each particular wound, and the underlying vascular disease. The goal is to achieve wound healing. Inappropriate care can retard healing or even aggravate the wound. The skin should be cleaned with water a non-allergic detergent and should concern the entire limb in addition to the wound itself. Fibrin or necrosis detersion is an important step that can be painful...
September 2016: Journal des Maladies Vasculaires
https://www.readbyqxmd.com/read/27587374/bone-marrow-edema-syndrome-in-the-foot-and-ankle
#18
REVIEW
Seyed Alireza Mirghasemi, Elly Trepman, Mohammad Saleh Sadeghi, Narges Rahimi, Shervin Rashidinia
: Bone marrow edema syndrome (BMES) is an uncommon and self-limited syndrome characterized by extremity pain of unknown etiology. Symptoms may include sudden or gradual onset of swelling and pain at rest or during activity, usually at night. This syndrome mostly affects middle-aged men and younger women who have pain in the lower extremities. The most common sites involved with BMES, in decreasing order of frequency, are the bones about the hip, knee, ankle, and foot. The diagnosis of BMES is confirmed with magnetic resonance imaging to exclude other causes of bone marrow edema...
December 2016: Foot & Ankle International
https://www.readbyqxmd.com/read/27575610/abnormal-bone-marrow-signal-intensity-in-the-phalanges-of-the-foot-as-a-manifestation-of-raynaud-phenomenon-a-report-of-six-patients
#19
Edward Smitaman, Bruno P G Pereira, Brady K Huang, Mina M Zakhary, Evelyne Fliszar, Donald L Resnick
OBJECTIVE: The objectives of our study were to describe the MRI findings of pedal phalangeal bone marrow edema in patients with Raynaud phenomenon (RP) and discuss the clinical implications of these MRI findings. CONCLUSION: There is a progressive distal-to-proximal pattern of pedal phalangeal bone marrow edema on MRI in patients with RP. This knowledge may allow early diagnosis and treatment of rheumatologic disorders that are potentially associated with RP.
December 2016: AJR. American Journal of Roentgenology
https://www.readbyqxmd.com/read/27556777/nutrition-and-chronic-wounds-improving-clinical-outcomes
#20
Joseph A Molnar, Lucian G Vlad, Tuna Gumus
There is increasing awareness that chronic wound healing is very dependent on the patient's nutritional status, but there are no clearly established and accepted assessment protocols or interventions in clinical practice. Much of the data used as guidelines for chronic wound patients are extrapolated from acutely wounded trauma patients, but the 2 groups are very different patient populations. While most trauma patients are young, healthy, and well-nourished before injury, the chronic wound patient is usually old, with comorbidities and frequently malnourished...
September 2016: Plastic and Reconstructive Surgery
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