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https://www.readbyqxmd.com/read/29778155/effect-of-phosphate-releasing-in-activated-sludge-on-phosphorus-removal-from-municipal-wastewater
#1
Jie Ge, Xiaoguang Meng, Yonghui Song, Amalia Terracciano
Aluminum and ferric salts are commonly used in municipal wastewater treatment plants (WWPTs) for phosphorus (P) removal. In this study, on-site jar tests were conducted to determine the removal of different P species from the fresh samples in the presence and absence of activated sludge (AS) with different doses of alum, poly-aluminum chloride, and ferric chloride at different pH. The soluble P (SP) concentration in the samples was about 0.63mg/L. When the mixed liquor containing AS was treated with 8mg/L of Al, SP could be reduced to 0...
May 2018: Journal of Environmental Sciences (China)
https://www.readbyqxmd.com/read/29775998/high-pressure-raman-study-of-type-i-collagen
#2
Amalia Maria Paschou, Maria Katsikini, Dimitrios Christofilos, John Arvanitidis, Sotirios Ves
The high pressure response of type-I collagen from bovine Achilles tendon is investigated with micro-Raman spectroscopy. Fluorinert™ and methanol-ethanol mixtures were used as pressure transmitting media (PTM) in a diamond anvil cell. The Raman spectrum of collagen is dominated by three bands centred at approximately 1450, 1660 and 2930 cm-1 , attributed to C-H deformation, C=O stretching of the peptide bond (amide-I band) and C-H stretching modes, respectively. Upon pressure increase, using Fluorinert™ as PTM, a shift towards higher frequencies of the C-H stretching and deformation peaks is observed...
May 18, 2018: FEBS Journal
https://www.readbyqxmd.com/read/29772884/validation-of-a-spatial-liver-fluke-model-under-field-conditions-in-ireland
#3
Amalia Naranjo Lucena, María Pía Munita Corbalán, Ana María Martínez-Ibeas, Guy McGrath, Riona Sayers, Grace Mulcahy, Annetta Zintl
Fasciola hepatica is the causative agent of fasciolosis, a global disease of a wide range of mammals, particularly sheep and cattle. Liver fluke infection causes annual losses estimated at around €2.5 billion to livestock and food industries worldwide. Various models have been developed to define risk factors and predict exposure to this liver fluke in ruminants in European countries, most of them based exclusively on data from dairy herds. The aim of this study was to validate a published theoretical baseline risk map of liver fluke exposure and cluster maps in Ireland, by including further explanatory variables and additional herd types that are spatially more widespread...
May 7, 2018: Geospatial Health
https://www.readbyqxmd.com/read/29772277/severity-therapeutic-and-activity-tear-biomarkers-in-dry-eye-disease-a-clinical-trial-sub-analysis
#4
José Pinto-Fraga, Amalia Enríquez-de-Salamanca, Margarita Calonge, María J González-García, Alberto López-Miguel, Alberto López-de la Rosa, Carmen García-Vázquez, Virginia Calder, Michael E Stern, Itziar Fernández
PURPOSE: To evaluate the effect of 0.1%-fluorometholone (FML) on tear inflammatory molecule levels after 22-days treatment in dry eye disease (DED) patients exposed to an adverse controlled environment (ACE), identifying different biomarkers. METHODS: Sub-analysis of a double-masked randomized clinical trial. Forty-one DED patients received 4-drops daily of topical FML (FML-group) or polyvinyl-alcohol (PA-group) for 22 days. At day 21, patients were exposed to an ACE...
May 14, 2018: Ocular Surface
https://www.readbyqxmd.com/read/29771369/building-the-burn-physician-workforce-for-the-21st-century-report-from-february-2014-burns-workforce-conference
#5
Amalia Cochran, David G Greenhalgh
American Burn Association Past President Palmer Q. Bessey, MD, orchestrated a Burn Workforce Conference in Washington, DC in February, 2014, with the goal of evaluating the workforce needs for doctors, nurses and occupational/physical therapists. This report summarizes the issues related to the need for training future surgeons to manage burn patients. General surgery and plastic surgery residents currently have minimal requirements for burn experience during their training. The respective Boards, however, do require knowledge in the management of burn care...
May 16, 2018: Journal of Burn Care & Research: Official Publication of the American Burn Association
https://www.readbyqxmd.com/read/29771329/regulation-of-the-neuropathy-associated-pmp22-gene-by-a-distal-super-enhancer
#6
Harrison Pantera, John J Moran, Holly A Hung, Evgenia Pak, Amalia Dutra, John Svaren
Peripheral nerve myelination is adversely affected in the most common form of the hereditary peripheral neuropathy called Charcot-Marie-Tooth Disease. This form, classified as CMT1A, is caused by a 1.4 Mb duplication on chromosome 17, which includes the abundantly expressed Schwann cell myelin gene, Peripheral Myelin Protein 22 (PMP22). This is one of the most common copy number variants causing neurological disease. Overexpression of Pmp22 in rodent models recapitulates several aspects of neuropathy, and reduction of Pmp22 in such models results in amelioration of the neuropathy phenotype...
May 16, 2018: Human Molecular Genetics
https://www.readbyqxmd.com/read/29769580/kv1-3-activity-perturbs-the-homeostatic-properties-of-astrocytes-in-glioma
#7
Alfonso Grimaldi, Giuseppina D'Alessandro, Maria Amalia Di Castro, Clotilde Lauro, Vikrant Singh, Francesca Pagani, Luigi Sforna, Francesca Grassi, Silvia Di Angelantonio, Luigi Catacuzzeno, Heike Wulff, Cristina Limatola, Myriam Catalano
Glial cells actively maintain the homeostasis of brain parenchyma, regulating neuronal excitability and preserving the physiological composition of the extracellular milieu. Under pathological conditions, some functions of glial cells could be compromised, exacerbating the neurotoxic processes. We investigated if the homeostatic activities of astrocytes and microglia could be modulated by the voltage-gated K+ channel Kv1.3. To this end we used in vitro and in vivo systems to model cell-to-cell interactions in tumoral conditions, using a specific inhibitor of Kv1...
May 16, 2018: Scientific Reports
https://www.readbyqxmd.com/read/29767567/impact-of-ntrk2-drd2-and-ace-polymorphisms-on-prolactin-levels-in-antipsychotic-treated-patients-with-first-episode-psychosis
#8
Patricia Gassó, Sergi Mas, Miquel Bioque, Bibiana Cabrera, Antonio Lobo, Ana González-Pinto, Covadonga M Díaz-Caneja, Iluminada Corripio, Eduard Vieta, Josefina Castro-Fornieles, Salvador Sarró, Anna Mané, Julio Sanjuan, Adrián Llerena, Amalia Lafuente, Jerónimo Saiz-Ruiz, Miguel Bernardo
BACKGROUND: Hyperprolactinemia is a common side-effect of antipsychotics (APs), which may trigger serious secondary problems and compromise the adherence to treatment which is crucial for prognosis, especially in patients presenting with a first-episode of psychosis (FEP). AIMS: We evaluated, in some cases for the first time, the effect of polymorphisms in multiple candidate genes on serum prolactin (PRL) levels in an AP-treated FEP cohort recruited in the multicenter PEPs study (Phenotype - genotype and environmental interaction; Application of a predictive model in first psychotic episodes)...
May 1, 2018: Journal of Psychopharmacology
https://www.readbyqxmd.com/read/29763556/gate-defined-quantum-confinement-in-inse-based-van-der-waals-heterostructures
#9
Matthew J Hamer, Endre Tóvári, Mengjian Zhu, Michael Dermot Thompson, Alexander S Mayorov, Jonathan Prance, Yongjin Lee, Richard Haley, Zakhar R Kudrynskyi, Amalia Patanè, Daniel Terry, Zakhar D Kovalyuk, Klaus Ensslin, Andrey V Kretinin, Andre K Geim, Roman Vladislavovich Gorbachev
Indium selenide, a post-transition metal chalcogenide, is a novel two-dimensional (2D) semiconductor with interesting electronic properties. Its tunable band gap and high electron mobility have already attracted considerable research interest. Here we demonstrate strong quantum confinement and manipulation of single electrons in devices made from few-layer crystals of InSe using electrostatic gating. We report on gate-controlled quantum dots in the Coulomb blockade regime as well as one-dimensional quantization in point contacts, revealing multiple plateaus...
May 15, 2018: Nano Letters
https://www.readbyqxmd.com/read/29755400/intermittent-hypoxia-is-associated-with-high-hypoxia-inducible-factor-1%C3%AE-but-not-high-vascular-endothelial-growth-factor-cell-expression-in-tumors-of-cutaneous-melanoma-patients
#10
Isaac Almendros, Miguel Ángel Martínez-García, Francisco Campos-Rodríguez, Erica Riveiro-Falkenbach, José L Rodríguez-Peralto, Eduardo Nagore, Antonio Martorell-Calatayud, Luis Hernández Blasco, Jose Bañuls Roca, Eusebi Chiner Vives, Alicia Sánchez-de-la-Torre, Jorge Abad-Capa, Josep Maria Montserrat, Amalia Pérez-Gil, Valentín Cabriada-Nuño, Irene Cano-Pumarega, Jaime Corral-Peñafiel, Trinidad Diaz-Cambriles, Olga Mediano, Joan Dalmau-Arias, Ramon Farré, David Gozal
Epidemiological associations linking between obstructive sleep apnea and poorer solid malignant tumor outcomes have recently emerged. Putative pathways proposed to explain that these associations have included enhanced hypoxia inducible factor (HIF)-1α and vascular endothelial growth factor (VEGF) cell expression in the tumor and altered immune functions via intermittent hypoxia (IH). Here, we examined relationships between HIF-1α and VEGF expression and nocturnal IH in cutaneous melanoma (CM) tumor samples...
2018: Frontiers in Neurology
https://www.readbyqxmd.com/read/29752967/hiv-1-matrix-protein-interactions-with-trna-implications-for-membrane-targeting
#11
Christy R Gaines, Emre Tkacik, Amalia Rivera-Oven, Phoebe Somani, Alecia Achimovich, Tawakalitou Alabi, Angela Zhu, Noel Getachew, Ae Lim Yang, Matthew McDonough, Tarik Hawkins, Zoe Spadaro, Michael F Summers
The N-terminally myristoylated matrix domain (MA) of the HIV-1 Gag polyprotein promotes virus assembly by targeting Gag to the inner leaflet of the plasma membrane (PM). Recent studies indicate that, prior to membrane binding, MA associates with cytoplasmic tRNAs (including tRNALys3 ), and in vitro studies of tRNA-dependent MA interactions with model membranes have led to proposals that competitive tRNA interactions contribute to membrane discrimination. We have characterized interactions between native, mutant, and unmyristylated (myr-) MA proteins and recombinant tRNALys3 by NMR spectroscopy and isothermal titration calorimetry (ITC)...
May 9, 2018: Journal of Molecular Biology
https://www.readbyqxmd.com/read/29750098/effect-of-surface-treatments-with-acid-solutions-on-the-surface-roughness-of-an-yttrium-tetragonal-zirconia-polycrystal
#12
Frederico Goyatá, Yvna Galvão, Thamyryz-Rafaela Simões, Luiz-Felipe Goyatá, José-Alcides Arruda, Amália Moreno
Background: The purpose of this in vitro study was to evaluate the effect of conventional surface treatment with acid solutions on the surface roughness of a zirconia-based ceramic. Material and Methods: Specimens of yttrium-tetragonal zirconia polycrystal (Y-TZP) -based ceramic were fabricated (5.0 x 5.0 x 2.0 mm, n=40). The specimens were submitted to the tested surface treatment method and divided into 4 groups (n=10): no treatment-control (GI), airborne 110 µm aluminum oxide particle abrasion for 1 minute-conventional method (GII); etching with 48% hydrofluoric acid for 2 minutes (GIII), and nitric acid/hydrofluoric acid etching for 2 minutes (GIV)...
April 2018: Journal of Clinical and Experimental Dentistry
https://www.readbyqxmd.com/read/29750093/laser-phototherapy-induces-angiogenesis-in-the-periodontal-tissue-after-delayed-tooth-replantation-in-rats
#13
Felipe-de Souza Matos, Fernanda-de Jesus Godolphim, Ricardo-Luiz-Cavalcanti Albuquerque-Júnior, Luiz-Renato Paranhos, Sigmar-de Mello Rode, Cláudio-Antonio-Talge Carvalho, Maria-Amália-Gonzaga Ribeiro
Background: Laser phototherapy (LPT) has been suggested as a new therapeutic tool to improve the repair of replanted teeth. However, its effects and mechanism of action are not yet completely understood. Objectives: This study evaluated histologically the effect of laser phototherapy (LPT) λ808 and λ660 nm on angiogenesis in the periodontal tissue of replanted teeth in rats. Material and Methods: Twenty maxillary right incisors were extracted from twenty Wistar rats and randomly assigned to four groups (n = 5): PN - teeth were stored in paper napkin for 45 min; WM - teeth were immersed in 20 ml of UHT whole cow milk for 45 min; PNL and WML - teeth received the same treatment described for PN and WM, respectively, plus LPT at λ808 and λ660 nm...
April 2018: Journal of Clinical and Experimental Dentistry
https://www.readbyqxmd.com/read/29749920/evolution-of-the-graded-repair-of-csf-leaks-and-skull-base-defects-in-endonasal-endoscopic-tumor-surgery-trends-in-repair-failure-and-meningitis-rates-in-509-patients
#14
Andrew Conger, Fan Zhao, Xiaowen Wang, Amalia Eisenberg, Chester Griffiths, Felice Esposito, Ricardo L Carrau, Garni Barkhoudarian, Daniel F Kelly
OBJECTIVE The authors previously described a graded approach to skull base repair following endonasal microscopic or endoscope-assisted tumor surgery. In this paper they review their experience with skull base reconstruction in the endoscopic era. METHODS A retrospective review of a single-institution endonasal endoscopic patient database (April 2010-April 2017) was undertaken. Intraoperative CSF leaks were graded based on size (grade 0 [no leak], 1, 2, or 3), and repair technique was documented across grades...
May 11, 2018: Journal of Neurosurgery
https://www.readbyqxmd.com/read/29747595/the-search-for-a-melanoma-tailored-chemotherapy-in-the-new-era-of-personalized-therapy-a-phase-ii-study-of-chemo-modulating-temozolomide-followed-by-fotemustine-and-a-cooperative-study-of-goim-gruppo-oncologico-italia-meridionale
#15
Michele Guida, Stefania Tommasi, Sabino Strippoli, Maria Iole Natalicchio, Simona De Summa, Rosamaria Pinto, Antonio Cramarossa, Anna Albano, Salvatore Pisconti, Michele Aieta, Ruggiero Ridolfi, Amalia Azzariti, Gabriella Guida, Vito Lorusso, Giusepe Colucci
BACKGROUND: It is frequently asked whether chemotherapy can still play a role in metastatic melanoma considering the effectiveness of the available drugs today, including antiCTLA4/antiPD1 immunotherapy and antiBRAF/antiMEK inhibitors. However, only approximately half of patients respond to these drugs, and the majority progress after 6-11 months. Therefore, a need for other therapeutic options is still very much apparent. We report the first large trial of a sequential full dose of fotemustine (FM) preceded by a low dose of temozolomide (TMZ) as a chemo-modulator in order to inactivate the DNA repair action of O(6)-methylguanine DNA-methyltransferase (MGMT)...
May 10, 2018: BMC Cancer
https://www.readbyqxmd.com/read/29747482/effectiveness-of-oral-propranolol-for-infantile-hemangiomas-started-after-5-months-of-age
#16
Teresa Lopez, Emanuele Miraglia, Amalia Schiavetti, Giulia Varrasso, Stefano Calvieri, Sandra Giustini
No abstract text is available yet for this article.
May 10, 2018: Giornale Italiano di Dermatologia e Venereologia: Organo Ufficiale, Società Italiana di Dermatologia e Sifilografia
https://www.readbyqxmd.com/read/29747449/iron-oxide-colloidal-nanoclusters-as-theranostic-vehicles-and-their-interactions-at-the-cellular-level
#17
Athanasia Kostopoulou, Konstantinos Brintakis, Eirini Fragogeorgi, Amalia Anthousi, Liberato Manna, Sylvie Begin-Colin, Claire Billotey, Anthi Ranella, George Loudos, Irene Athanassakis, Alexandros Lappas
Advances in surfactant-assisted chemical approaches have led the way for the exploitation of nanoscale inorganic particles in medical diagnosis and treatment. In this field, magnetically-driven multimodal nanotools that perform both detection and therapy, well-designed in size, shape and composition, are highly advantageous. Such a theranostic material—which entails the controlled assembly of smaller (maghemite) nanocrystals in a secondary motif that is highly dispersible in aqueous media—is discussed here...
May 9, 2018: Nanomaterials
https://www.readbyqxmd.com/read/29744955/the-effect-of-high-pre-slaughter-environmental-temperature-on-meat-quality-traits-of-italian-autochthonous-pig-suino-nero-lucano
#18
Amalia Simonetti, Annamaria Perna, Roberto Giudice, Angelo Cappuccio, Emilio Gambacorta
The aim of the present study was to evaluate the effect of high pre-slaughter environmental temperature on meat (Longissimus lumborum muscle) quality traits of Italian autochthonous pigs Suino Nero Lucano (SNL). High pre-slaughter environmental temperature influenced the meat quality of autochthonous pigs. In particular, the meat from SNL pigs exposed to heat stress (H) showed significantly lower pH values at 24 and 48 hr post mortem, haem iron content and redness (a*) value, and a significantly higher shear force, drip loss and lightness (L*) values, compared to meat from SNL pigs reared under comfortable environmental temperature (C)...
May 9, 2018: Animal Science Journal, Nihon Chikusan Gakkaihō
https://www.readbyqxmd.com/read/29742972/validity-and-clinical-utility-of-different-clock-drawing-test-scoring-systems-in-multiple-forms-of-dementia
#19
Diana Duro, Miguel Tábuas-Pereira, Sandra Freitas, Beatriz Santiago, Maria Amália Botelho, Isabel Santana
The Clock Drawing Test (CDT) has a known potential for the detection of cognitive impairment in populations with dementia, especially Alzheimer disease (AD). Our aim was to compare the clinical utility of 3 CDT scoring systems (Rouleau, Cahn, and Babins) in several pathologies with cognitive compromise from a tertiary center memory clinic. We selected patients with a clinical diagnosis of mild stage AD, behavioral variant frontotemporal dementia (FTD), vascular dementia (VaD), dementia with Lewy bodies (DLB), and Parkinson disease with dementia (PDD)...
January 1, 2018: Journal of Geriatric Psychiatry and Neurology
https://www.readbyqxmd.com/read/29741917/a-systematic-review-of-pharmacologic-treatments-for-school-refusal-behavior
#20
Amalia Londono Tobon, Margot O Reed, Jerome H Taylor, Michael H Bloch
OBJECTIVE: School refusal is an important pediatric problem with significant negative short- and long-term outcomes. Specific psychosocial treatments appear effective in reducing school refusal, but many children do not respond to these treatments. Although systematic reviews have examined the efficacy of psychological interventions for school refusal, no systematic reviews on pharmacological interventions exist. METHODS: We conducted a comprehensive literature search of MEDLINE, PsycINFO, Scopus, and Embase for randomized controlled trials (RCTs) or quasi-experimental pharmacologic trials in children and adolescents with school refusal reported in English or Spanish until July 1, 2017...
May 9, 2018: Journal of Child and Adolescent Psychopharmacology
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