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Min-Wu Guan, Jia-Yin Wang, Dong-Xia Feng, Paul Fu, Li-Hua Chen, Ming-Chu Li, Qiu-Hang Zhang, Amir Samii, Madjid Samii, Feng Kong, Zhi-Ping Zhang, Ling Chen
BACKGROUND: Image-guided neurosurgery, endoscopic-assisted neurosurgery and the keyhole approach are three important parts of minimally invasive neurosurgery and have played a significant role in treating skull base lesions. This study aimed to investigate the potential usefulness of coupling of the endoscope with the far lateral keyhole approach and image guidance at the ventral craniocervical junction in a cadaver model. METHODS: We simulated far lateral keyhole approach bilaterally in five cadaveric head specimens (10 cranial hemispheres)...
May 2013: Chinese Medical Journal
Anhua Wu, Joseph M Zabramski, Pakrit Jittapiromsak, Robert C Wallace, Robert F Spetzler, Mark C Preul
BACKGROUND: The rationale for choosing between the condylar fossa and transcondylar variations of the far-lateral approach requires understanding of the relationships between the occipital condyle, jugular tubercle, and hypoglossal canal. OBJECTIVE: We examined the anatomic relationship of these 3 structures and analyzed the effect that changes in these relationships have on the surgical exposure and angle of attack for these 2 approaches. METHODS: Anatomic measurements of 5 cadaveric heads from 3-dimensional computed tomographic scans were compared with direct measurements of the same specimens...
June 2010: Neurosurgery
Sam Safavi-Abbasi, Joseph M Zabramski, Pushpa Deshmukh, Cassius V Reis, Nicholas C Bambakidis, Nicholas Theodore, Neil R Crawford, Robert F Spetzler, Mark C Preul
OBJECT: The authors quantitatively assessed the effects of balloon inflation as a model of tumor compression on the brainstem, cranial nerves, and clivus by measuring the working area, angle of attack, and brain shift associated with the retrosigmoid approach. METHODS: Six silicone-injected cadaveric heads were dissected bilaterally via the retrosigmoid approach. Quantitative data were generated, including key anatomical points on the skull base and brainstem. All parameters were measured before and after inflation of a balloon catheter (inflation volume 4...
October 2007: Journal of Neurosurgery
Rungsak Siwanuwatn, Pushpa Deshmukh, Eberval Gadelha Figueiredo, Neil R Crawford, Robert F Spetzler, Mark C Preul
OBJECT: The authors quantitatively assessed the working areas and angles of attack associated with retrosigmoid (RS), combined petrosal (CP), and transcochlear (TC) craniotomies. METHODS: Four silicone-injected cadaveric heads were bilaterally dissected using three approaches progressing from the least to the most extensive. Working areas were determined using the Optotrak 3020 system on the upper and middle thirds of the petroclivus and brainstem. Angles of attack were studied using the Elekta SurgiScope at the Dorello canal and the origin of the anterior inferior cerebellar artery (AICA)...
January 2006: Journal of Neurosurgery
Sun Ha Paek, Chae-Yong Kim, Young Yim Kim, In Ae Park, Min Seok Kim, Dong Gyu Kim, Hee-Won Jung
Peritumoral edema (PTE) in meningioma occurs variably and can adversely affect the clinical course. Moreover, the etiology of PTE in meningioma is not well documented. To examine possible correlations with PTE, the authors investigated the clinical parameters and the expressions of vascular endothelial growth factor (VEGF), matrix metalloproteinases (MMPs), and their inhibitors (TIMPs) in 20 meningiomas. The estimation of tumor volume (V(T)) and edema volume (V(E)) was done using Osiris software with magnetic resonance images and the edema index (EI) was calculated...
December 2002: Journal of Neuro-oncology
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