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DSM 5.1

F Kazour, C Awaida, L Souaiby, S Richa
INTRODUCTION: Cannabis use is very frequent in bipolar disorder and has been found to increase the duration and frequency of manic symptoms while decreasing those of depression. Bipolar patients who use cannabis were shown to have poorer compliance to treatment, more symptoms that are psychotic and a worse prognosis than patients who do not. In this study, we have evaluated the importance of cannabis use among bipolar patients admitted to the Psychiatric Hospital of the Cross, Lebanon (Hôpital Psychiatrique de la Croix [HPC]) as well as the clinical differences between cannabis users and non-users...
October 10, 2016: L'Encéphale
Emily Moulton, Kathryn Bradbury, Marianne Barton, Deborah Fein
The Childhood Autism Rating Scale (CARS), (Schopler et al. in J Autism Dev Disord 10(1):91-103, 1980) is a 15-item observation-based rating scale that yields a total score reflective of autism symptom severity. This study investigated the factor structure of the CARS in a sample of 2-year-old children with DSM-IV-TR (American Psychiatric Association in Diagnostic and statistical manual of mental disorders, 4th edn. American Psychiatric Publishing, Washington, 2000) diagnoses of AD or PDD-NOS. Following a preliminary internal cross-validation, principal axis factor analysis was completed (N = 282)...
October 14, 2016: Journal of Autism and Developmental Disorders
Francesca Deidda, Angela Amoruso, Serena Allesina, Marco Pane, Teresa Graziano, Mario Del Piano, Luca Mogna
GOALS: This study was undertaken to demonstrate the ability of Lactobacillus fermentum LF5 (DSM 32277) to inhibit in vitro different Candida species and Gardnerella vaginalis to weigh its potential effectiveness even in mixed vaginal infections. BACKGROUND: A wide female population is suffering from various vulvovaginal infections. These diseases are often associated with a decrease in the concentration of Lactobacilli in the vagina. Mixed vaginal infections represent >20% of women with vulvovaginal infection...
November 2016: Journal of Clinical Gastroenterology
Mario Del Piano, Francesco Coggiola, Marco Pane, Angela Amoruso, Stefania Nicola, Luca Mogna
BACKGROUND: Diarrhea accounts for 9% of the mortality among children under 5 years of age worldwide, and it is significantly associated with malnutrition. Each year, diarrhea kills around 760,000 children under 5 years of age and most of these are in sub-Saharan Africa.In Uganda, the infant mortality rate of 58 per 1000 is unacceptably high, and the major contributors include malnutrition, diarrhea, pneumonia, malaria, prematurity, sepsis, and newborn illnesses.There is an urgent need for intervention to prevent and control diarrheal diseases...
November 2016: Journal of Clinical Gastroenterology
Edward C Lauterbach
Dextromethorphan (DM) may have ketamine-like rapid-acting, treatment-resistant, and conventional antidepressant effects.(1,2) This reports our initial experience with DM in unipolar Major Depressive Disorder (MDD). A patient with treatment-resistant MDD (failing adequate trials of citalopram and vortioxetine) with loss of antidepressant response (to fluoxetine and bupropion) twice experienced a rapid-acting antidepressant effect within 48 hours of DM administration and lasting 7 days, sustained up to 20 days with daily administration, then gradually developing labile loss of antidepressant response over the ensuing 7 days...
August 15, 2016: Psychopharmacology Bulletin
David Mischoulon, Lindsay Hylek, Albert S Yeung, Alisabet J Clain, Lee Baer, Cristina Cusin, Dawn Flosnik Ionescu, Jonathan E Alpert, David P Soskin, Maurizio Fava
BACKGROUND: Given the proposed dopaminergic mechanism of low-dose naltrexone (LDN), we examined its efficacy as augmentation for depressive breakthrough on pro-dopaminergic antidepressant regimens. METHODS: 12 adults (67% female, mean age = 45±12) with recurrent DSM-IV major depressive disorder (MDD) on dopaminergic antidepressant regimens (stimulants, dopamine agonists, bupropion [≥300mg/day], aripiprazole [≤2.5mg/day], or sertraline [≥150mg/day]) were randomized to naltrexone 1mg b...
October 1, 2016: Journal of Affective Disorders
Jun Zhang, Xiao-Tong Ma, Jun-Sheng Gao, Cai-Wen Zhang, Juan-Juan Zhao, Rui-Jie Zhang, Li-An Ma, Xiao-Xia Zhang
A novel bacterium, strain 1ZS3-15(T), was isolated from rhizosphere of rice. Its taxonomic position was investigated using a polyphasic approach. The novel strain was observed to be Gram-stain positive, spore-forming, aerobic, motile and rod-shaped. Phylogenetic analysis based on 16S rRNA gene sequences showed that strain 1ZS3-15(T) was recovered within the genus Paenibacillus. It is closely related to Paenibacillus pectinilyticus KCTC 13222(T) (97.9 % similarity), Paenibacillus frigoriresistens CCTCC AB 2011150(T) (96...
October 12, 2016: Antonie Van Leeuwenhoek
Susan G Kornstein, Jelena L Kunovac, Barry K Herman, Larry Culpepper
OBJECTIVE: Review the clinical skills needed to recognize, diagnose, and manage binge-eating disorder (BED) in a primary care setting. DATA SOURCES: A PubMed search of English-language publications (January 1, 2008-December 11, 2014) was conducted using the term binge-eating disorder. Relevant articles known to the authors were also included. STUDY SELECTION/DATA EXTRACTION: Publications focusing on preclinical topics (eg, characterization of receptors and neurotransmitter systems) without discussing clinical relevance were excluded...
2016: Primary Care Companion to CNS Disorders
Mary de Groot, Kent A Crick, Molly Long, Chandan Saha, Jay H Shubrook
OBJECTIVE: Depression in patients with type 2 diabetes (T2D) is associated with long-term complications, disability, and early mortality. No studies have systematically examined the length of episodes and remission in adults with major depressive disorder (MDD) and T2D. This study examined the course of depressive disorders in patients with T2D and MDD. RESEARCH DESIGN AND METHODS: Participants (N = 50) enrolled in a behavioral intervention for adults with T2D and MDD were interviewed using the Structured Clinical Interview for DSM-IV-TR to assess history of depressive disorders at baseline (lifetime history), postintervention, and 3-month follow-up...
October 11, 2016: Diabetes Care
Eugene Kinyanda, Helen A Weiss, Jonathan Levin, Noeline Nakasujja, Harriet Birabwa, Juliet Nakku, Richard Mpango, Heiner Grosskurth, Soraya Seedat, Ricardo Araya, Vikram Patel
Data on the course of major depressive disorder (MDD) among people living with HIV (PLWH) are needed to inform refinement of screening and interventions for MDD. This paper describes the incidence and persistence rate of MDD in PLWH in Uganda. 1099 ART-naïve PLWH attending HIV clinics in Uganda were followed up for 12 months. MDD was assessed using the DSM IV based Mini-International Neuropsychiatric Interview with a prevalence for MDD at baseline of 14.0 % (95 % CI 11.7-16.3 %) reported. Multivariable logistic regression was used to determine predictors of incident and persistent MDD...
October 8, 2016: AIDS and Behavior
Björn Karlsson, Robert Sigström, Svante Östling, Margda Waern, Anne Börjesson-Hanson, Ingmar Skoog
OBJECTIVES: To examine the prevalence of social anxiety disorders (SAD) with (DSM-IV) and without (DSM-5) the person's own assessment that the fear was unreasonable, in a population sample of older adults. Further, to determine whether clinical and sociodemographic correlates of SAD differ depending on the criteria applied. DESIGN: Cross-sectional. SETTING: General population in Gothenburg, Sweden. PARTICIPANTS: A random population-based sample of 75- and 85-year olds (N = 1200) without dementia...
August 3, 2016: American Journal of Geriatric Psychiatry
E Mesman, E A Youngstrom, N K Juliana, W A Nolen, M H J Hillegers
OBJECTIVE: To validate the Seven Up Seven Down (7U7D), an abbreviated version of the General Behavior Inventory (GBI), as screener for mood disorders and test its ability to predict mood disorders over time in individuals at risk for bipolar disorder (BD). METHODS: Bipolar offspring (n=108) were followed from adolescence into adulthood and assessed at baseline, 1-, 5- and 12 years follow-up (T1-T4 respectively). Offspring were assessed using the Schedule for Affective Disorders and Schizophrenia for School-Age Children--Present and Lifetime Version, Structured Clinical Interview for DSM-IV Axis I Disorders and the GBI...
September 23, 2016: Journal of Affective Disorders
Tolga Binbay, Deniz Arık Binbay, Halis Ulaş, Köksal Alptekin
OBJECTIVE: To provide registry-based prevalence estimates of schizophrenia, schizoaffective, and bipolar I (BPI) disorders in a defined area of Sinop, Turkey. MATERIAL AND METHODS: All patients that presented to primary and secondary health services over three year time (2009-2011) with diagnosis of psychotic disorder (F06.1, F06.2, F10.5, F12.5, F19.5, F20-29, F30-31, F32.3, F33.3, F39 in ICD-10) covering a population of 73,503 aged 15-64 were included via case registry systems...
2016: Türk Psikiyatri Dergisi, Turkish Journal of Psychiatry
Eric Stice, Jeff M Gau, Paul Rohde, Heather Shaw
Because no single report has examined risk factors that predict future onset each type of eating disorder and core symptom dimensions that crosscut disorders, we addressed these aims to advance knowledge regarding risk factor specificity. Data from 3 prevention trials that targeted young women with body dissatisfaction (N = 1,272; Mage = 18.5, SD = 4.2) and collected annual diagnostic interview data over 3-year follow-up were combined to identify predictors of subthreshold/threshold anorexia nervosa (AN), bulimia nervosa (BN), binge eating disorder (BED), and purging disorder (PD)...
October 6, 2016: Journal of Abnormal Psychology
Rich Boden, Lee P Hutt, Marcel Huntemann, Alicia Clum, Manoj Pillay, Krishnaveni Palaniappan, Neha Varghese, Natalia Mikhailova, Dimitrios Stamatis, Tatiparthi Reddy, Chew Yee Ngan, Chris Daum, Nicole Shapiro, Victor Markowitz, Natalia Ivanova, Tanja Woyke, Nikos Kyrpides
Thermithiobacillus tepidarius DSM 3134(T) was originally isolated (1983) from the waters of a sulfidic spring entering the Roman Baths (Temple of Sulis-Minerva) at Bath, United Kingdom and is an obligate chemolithoautotroph growing at the expense of reduced sulfur species. This strain has a genome size of 2,958,498 bp. Here we report the genome sequence, annotation and characteristics. The genome comprises 2,902 protein coding and 66 RNA coding genes. Genes responsible for the transaldolase variant of the Calvin-Benson-Bassham cycle were identified along with a biosynthetic horseshoe in lieu of Krebs' cycle sensu stricto...
2016: Standards in Genomic Sciences
Kaoru Seike, Michiko Nakazato, Hisashi Hanazawa, Toshiyuki Ohtani, Tomihisa Niitsu, Shin-Ichi Ishikawa, Atsuko Ayabe, Ryoko Otani, Kentaro Kawabe, Fumie Horiuchi, Shizuo Takamiya, Ryoichi Sakuta
BACKGROUND: The lowering of the age of onset and chronicity have been key problems related to eating disorders (EDs). As the proportion of teens in the estimated onset ages has increased, it has become important to detect students with EDs and to clarify how they can be supported. Though epidemiological surveys of Yogo teachers (school nurse/health science teachers) have been conducted to inquire about the number of such students, none of these were done according to ED type based on DSM-5...
2016: BioPsychoSocial Medicine
Luis Franca, Luciana Albuquerque, De-Chao Zhang, Imen Nouioui, Hans-Peter Klenk, Milton S da Costa, Rosa Margesin
A positive Gram-staining, non-motile, catalase-positive and cytochrome c oxidase-negative bacterium, designated strain S20-107T, was isolated from alpine forest soil. Growth occurred at a temperature range of 0-30 °C, at pH 6-9 and in the presence of 0-3 % (w/v) NaCl. Phylogenetic analysis based on 16S rRNA gene sequence showed that strain S20-107T was related to the genus Nakamurella and had the highest 16S rRNA gene sequence similarity with the type strain of Nakamurella flavida DS-52T (96.1 %). Strain S20-107T showed <96...
October 4, 2016: International Journal of Systematic and Evolutionary Microbiology
Krishna Vaddiparti, Catherine W Striley, Linda B Cottler
The purpose of this study is to assess the association between gambling severity and exposure to guns among substance-using women recruited in the community. Data for these analyses come from the baseline phase of two community-based HIV prevention interventions conducted among alcohol and drug-using women in St. Louis, MO. Gun exposure was assessed using the Violence Exposure Questionnaire (VEQ), and DSM-IV pathological gambling (PG) symptoms and other psychiatric symptoms were assessed using the Computerized Diagnostic Interview Schedule; The Composite International Diagnostic Interview Substance Abuse Module assessed DSM-IV substance dependence, including cocaine dependence and alcohol dependence...
September 1, 2016: Violence Gend
Roxanne Gaspersz, Femke Lamers, Justine M Kent, Aartjan T F Beekman, Johannes H Smit, Albert M van Hemert, Robert A Schoevers, Brenda W J H Penninx
Evidence has shown that the DSM-5 anxious distress specifier captures a clinically valid construct that predicts a worse clinical course. Although of importance for treatment planning and monitoring, however, the specifier's ability to predict treatment outcome is unknown. This is the first study to examine the ability of the DSM-5 anxious distress specifier to predict treatment response and side effects in depressed patients who recently initiated antidepressant treatment. Patients were from the Netherlands Study of Depression and Anxiety, an ongoing longitudinal cohort study...
September 21, 2016: Journal of Psychiatric Research
Sherita Hill Golden, Nina Shah, Mohammad Naqibuddin, Jennifer L Payne, Felicia Hill-Briggs, Gary S Wand, Nae-Yuh Wang, Susan Langan, Constantine Lyketsos
OBJECTIVE: To estimate the crude prevalence of minor depressive disorder (MinD) in a clinic-based population of adults with type 2 diabetes. METHODS: We screened a clinical sample of 702 adults with type 2 diabetes for depressive symptoms using the Patient Health Questionnaire-2 and performed a structured diagnostic psychiatric interview on 52 screen-positive and a convenience sample of 51 screen-negative individuals. Depressive disorder diagnoses were made using Diagnostic and Statistical Manual of Mental Disorders IV (DSM-IV) Text Revised criteria and categorized as MinD, major depressive disorder (MDD), or no depressive disorder...
August 15, 2016: Psychosomatics
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