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https://www.readbyqxmd.com/read/29219753/resection-of-primary-motor-cortex-tumors-feasibility-and-surgical-outcomes
#1
Stephen T Magill, Seunggu J Han, Jing Li, Mitchel S Berger
OBJECTIVE Brain tumors involving the primary motor cortex are often deemed unresectable due to the potential neurological consequences that result from injury to this region. Nevertheless, we have challenged this dogma for many years and used asleep, as well as awake, intraoperative stimulation mapping to maximize extent of resection. It remains unclear whether these tumors can be resected with acceptable morbidity, whether performing the surgery with the patient awake or asleep impacts extent of resection, and how stimulation mapping influences outcomes...
December 8, 2017: Journal of Neurosurgery
https://www.readbyqxmd.com/read/29218729/structural-and-molecular-heterogeneity-of-calretinin-expressing-interneurons-in-the-rodent-and-primate-striatum
#2
Farid N Garas, Eszter Kormann, Rahul S Shah, Federica Vinciati, Yoland Smith, Peter J Magill, Andrew Sharott
Calretinin-expressing (CR+) interneurons are the most common type of striatal interneuron in primates. However, because CR+ interneurons are relatively scarce in rodent striatum, little is known about their molecular and other properties, and they are typically excluded from models of striatal circuitry. Moreover, CR+ interneurons are often treated in models as a single homogenous population, despite previous descriptions of their heterogeneous structures and spatial distributions in rodents and primates. Here, we demonstrate that, in rodents, the combinatorial expression of secretagogin (Scgn), specificity protein 8 (SP8) and/or LIM homeobox protein 7 (Lhx7) separates striatal CR+ interneurons into 3 structurally- and topographically-distinct cell populations...
December 8, 2017: Journal of Comparative Neurology
https://www.readbyqxmd.com/read/29172594/trajectories-of-in-session-change-language-in-brief-motivational-interventions-with-mandated-college-students
#3
Brian Borsari, Timothy R Apodaca, Kristina M Jackson, Anne Fernandez, Nadine R Mastroleo, Molly Magill, Nancy P Barnett, Kate B Carey
OBJECTIVE: Brief motivational interventions (BMIs) are currently the most efficacious individual intervention for mandated college students. However, little is known about how BMIs facilitate client language in relation to subsequent changes in alcohol use and problems in mandated student samples. METHOD: The current study used the Motivational Interviewing Skills Code (MISC 2.0; Miller, Moyers, Ernst, & Amrhein, 2003) to code BMI sessions (N = 252) from 2 randomized clinical trials that led to significant reductions in alcohol use and alcohol-related problems in mandated student drinkers...
November 27, 2017: Journal of Consulting and Clinical Psychology
https://www.readbyqxmd.com/read/29170787/synthesis-computational-and-spectroscopic-analysis-of-tunable-highly-fluorescent-bn-1-2-azaborine-derivatives-containing-the-n-boh-moiety
#4
Carl Jacky Saint-Louis, Renée N Shavnore, Caleb D C McClinton, Julie A Wilson, Lacey L Magill, Breanna M Brown, Robert W Lamb, Charles Edwin Webster, Alan K Schrock, Michael T Huggins
Nine new polycyclic aromatic BN-1,2-azaborine analogues containing the N-BOH moiety were synthesized using a convenient two-step, one-pot procedure. Characterization of the prepared compounds show the luminescence wavelength and the quantum yields of the azaborines were tunable by controlling the power and location of the donor and acceptor substituents on the chromophore. UV-visible spectroscopy and density functional theory (DFT) computations revealed that the addition of electron-donating moieties to the isoindolinone hemisphere raised the energy of the HOMO, resulting in the reduction of the HOMO-LUMO gap...
November 24, 2017: Organic & Biomolecular Chemistry
https://www.readbyqxmd.com/read/29119804/longitudinal-patterns-of-early-development-in-canadian-late-preterm-infants-a-prospective-cohort-study
#5
Karen M Benzies, Joyce Magill-Evans, Marilyn Ballantyne, Jana Kurilova
This prospective, longitudinal cohort study examined longitudinal patterns of early development in Canadian children born late preterm. A convenience sample of 82 mothers and their healthy, singleton, late preterm children participated. Mothers completed the Ages and Stages Questionnaires at 4, 8, and 18 months corrected age. Concerns were most commonly reported in the communication and gross motor domains, especially early in development. The proportion of children scoring below the referral cut-off in at least one domain at 4, 8, and 18 months was, respectively, 25...
March 2017: Journal of Child Health Care: for Professionals Working with Children in the Hospital and Community
https://www.readbyqxmd.com/read/29097072/recommendations-for-randomised-trials-in-surgical-oncology
#6
J C Glasbey, E L Magill, K Brock, S P Bach
Trials of surgical procedures in the treatment of malignant disease face a unique set of challenges. This review aimed to describe recommendations for the design, delivery and reporting of randomised trials in surgical oncology. A literature search was carried out without date limits to identify articles related to trial methodology research in surgery and surgical oncology. A narrative review was framed around two open National Institute of Health Research portfolio trials in colon and rectal cancer: the STAR-TREC trial (ISRCTN14240288) and the ROCCS trial (ISRCTN46330337)...
October 30, 2017: Clinical Oncology: a Journal of the Royal College of Radiologists
https://www.readbyqxmd.com/read/29076750/investigation-of-dental-cone-beam-ct-pixel-data-and-a-modified-method-for-conversion-to-hounsfield-units-hu
#7
Dennise Magill, Natalie Beckmann, Marc A Felice, Thomas Yoo, Minou Luo, Mel Mupparapu
OBJECTIVES: To investigate the relationship in dental Cone-Beam CT (CBCT) between the manufacturer-reported image pixel data and a modified conversion to CT number densities in Hounsfield Units (HU). METHODS: A standardized CT phantom was imaged using typical clinical parameters on CBCT from 3 manufacturers (Carestream 9300®, J Morita 3D Accutomo®, and Planmeca Promax 3D®). Reconstructed axial slices were evaluated using regions of interest to ascertain the mean pixel value in 5 materials in the phantom...
October 27, 2017: Dento Maxillo Facial Radiology
https://www.readbyqxmd.com/read/29062062/localised-genetic-heterogeneity-provides-a-novel-mode-of-evolution-in-dsdna-phages
#8
Damian J Magill, Phillip A Kucher, Victor N Krylov, Elena A Pleteneva, John P Quinn, Leonid A Kulakov
The Red Queen hypothesis posits that antagonistic co-evolution between interacting species results in recurrent natural selection via constant cycles of adaptation and counter-adaptation. Interactions such as these are at their most profound in host-parasite systems, with bacteria and their viruses providing the most intense of battlefields. Studies of bacteriophage evolution thus provide unparalleled insight into the remarkable elasticity of living entities. Here, we report a novel phenomenon underpinning the evolutionary trajectory of a group of dsDNA bacteriophages known as the phiKMVviruses...
October 23, 2017: Scientific Reports
https://www.readbyqxmd.com/read/29059008/narrative-review-of-contemporary-treatment-options-in-the-care-of-patients-with-obstructive-sleep-apnoea
#9
Mark S Ferguson, Jennifer Claire Magill, Bhik T Kotecha
Snoring and obstructive sleep apnoea (OSA) are increasingly common conditions, and confer a significant health and socioeconomic burden. Furthermore, untreated OSA represents a significant mortality risk. Patients require careful assessment, including detailed clinical history and examination, sleep study and drug-induced sleep endoscopy (DISE). Although nasal continuous positive airway pressure (nCPAP) is the gold standard treatment for moderate and severe OSA, multidisciplinary team assessment is often required to develop the best treatment plan for an individual, especially when nasal CPAP is poorly tolerated...
October 1, 2017: Therapeutic Advances in Respiratory Disease
https://www.readbyqxmd.com/read/29046919/female-gonadal-shielding-with-automatic-exposure-control-increases-radiation-risks
#10
Summer L Kaplan, Dennise Magill, Marc A Felice, Rui Xiao, Sayed Ali, Xiaowei Zhu
BACKGROUND: Gonadal shielding remains common, but current estimates of gonadal radiation risk are lower than estimated risks to colon and stomach. A female gonadal shield may attenuate active automatic exposure control (AEC) sensors, resulting in increased dose to colon and stomach as well as to ovaries outside the shielded area. OBJECTIVE: We assess changes in dose-area product (DAP) and absorbed organ dose when female gonadal shielding is used with AEC for pelvis radiography...
October 18, 2017: Pediatric Radiology
https://www.readbyqxmd.com/read/29033738/magill-forceps-a-savior-in-bronchoscopy
#11
Teena Bansal, Shilpa Popli, Nidhi Bangarwa, Sudhir Kumar, Pushpa Yadav
No abstract text is available yet for this article.
October 2017: Saudi Journal of Anaesthesia
https://www.readbyqxmd.com/read/29026868/antifungal-susceptibility-testing-practices-at-acute-care-hospitals-enrolled-in-the-national-healthcare-safety-network-united-states-2011-2015
#12
Snigdha Vallabhaneni, Mathew Sapiano, Lindsey M Weiner, Shawn R Lockhart, Shelley Magill
We assessed availability of antifungal susceptibility testing (AFST) at nearly 4000 acute care hospitals enrolled in the National Healthcare Safety Network. In 2015, 95% offered any AFST, 28% offered AFST at their own laboratory or at an affiliated medical center, and 33% offered reflexive AFST. Availability of AFST improved from 2011 to 2015, but substantial gaps exist in the availability of AFST.
2017: Open Forum Infectious Diseases
https://www.readbyqxmd.com/read/28981312/intimate-violence-as-it-relates-to-risky-sexual-behavior-among-at-risk-females
#13
Danielle C Hill, L A R Stein, Joseph S Rossi, Molly Magill, Jennifer G Clarke
OBJECTIVE: Rates of sexually transmitted infections (STIs) among adolescents are on the rise. The majority of adolescents who contract STIs do so through risky sexual behavior. Previous literature has identified multiple correlates of risky sexual behaviors among adolescents, including physical and sexual victimization, mental health concerns, and substance use. Few studies, however, have examined these relationships together in a comprehensive model. The primary purpose of this study was to examine whether relationship violence was related to risky sexual behavior, and whether mental health symptoms and substance use mediated this relationship...
October 5, 2017: Psychological Trauma: Theory, Research, Practice and Policy
https://www.readbyqxmd.com/read/28952139/randomized-comparison-of-the-effectiveness-of-nasal-intubation-using-a-glidescope-video-laryngoscope-with-magill-forceps-versus-vascular-forceps-in-patients-with-a-normal-airway
#14
Jong H Yeom, Mi K Oh, Woo J Shin, Dae W Ahn, Woo J Jeon, Sang Y Cho
PURPOSE: The GlideScope® video laryngoscope (GVL) is widely used for nasotracheal intubation in dental and facial plastic surgery. The angle of the Magill forceps is different from that of the GVL blade, which suggests that the Magill forceps are not the ideal forceps for use with the GVL. The purpose of this study was to compare the effectiveness of the Magill forceps vs vascular forceps for nasotracheal intubation using the GVL. METHODS: This study included 60 patients scheduled to undergo elective surgery requiring nasotracheal intubation...
December 2017: Canadian Journal of Anaesthesia, Journal Canadien D'anesthésie
https://www.readbyqxmd.com/read/28921537/nasotracheal-intubation-over-a-bougie-vs-non-bougie-intubation-a-prospective-randomised-controlled-trial-in-older-children-and-adults-using-videolaryngoscopy
#15
R O Abrons, M B Zimmerman, Y M S El-Hattab
Conventionally, nasotracheal intubation has consisted of blind nasal passage and external manipulation of the tube through the glottis ('conventional technique'), a technique associated with a high incidence of nasal trauma. We evaluated a novel technique for routine asleep (i.e. post-induction) nasotracheal intubation using a bougie ('bougie technique'), which uses a nasopharyngeal airway to guide a paediatric bougie nasotracheally for use as a Seldinger tracheal intubation guide. Two hundred and fifty-seven older children (> 8 years) and adults were randomly assigned to videolaryngoscopy-assisted nasotracheal intubation using either the conventional or the bougie technique...
September 15, 2017: Anaesthesia
https://www.readbyqxmd.com/read/28877269/pf16-and-phipmw-expanding-the-realm-of-pseudomonas-putida-bacteriophages
#16
Damian J Magill, Victor N Krylov, Olga V Shaburova, John W McGrath, Christopher C R Allen, John P Quinn, Leonid A Kulakov
We present the analysis of two novel Pseudomonas putida phages, pf16 and phiPMW. Pf16 represents a peripherally related T4-like phage, and is the first of its kind infecting a Pseudomonad, with evidence suggesting cyanophage origins. Extensive divergence has resulted in pf16 occupying a newly defined clade designated as the pf16-related phages, lying at the interface of the Schizo T-Evens and Exo T-Evens. Recombination with an ancestor of the P. putida phage AF is likely responsible for the tropism of this phage...
2017: PloS One
https://www.readbyqxmd.com/read/28858136/comparison-of-a-curved-forceps-with-a-conventional-straight-forceps-for-nasogastric-tube-insertion-under-videolaryngoscopic-guidance-a-randomized-crossover-manikin-study
#17
RANDOMIZED CONTROLLED TRIAL
Kenta Furutani, Tatsunori Watanabe, Yoshinori Kamiya, Hiroshi Baba
BACKGROUND: Nasogastric tube (NGT) insertion is an easy procedure that can be routinely performed under general anesthesia. However, for difficult cases, there are limited insertion techniques available in routine clinical practice, considering the flexibility of NGTs. The SUZY curved forceps are designed for the removal of pharyngolaryngeal foreign bodies under guidance of the McGRATH MAC (McG) videolaryngoscope. Because McG enables clear visualization of the esophageal inlet, we hypothesized that the SUZY forceps can facilitate easier NGT insertion compared with the conventional Magill forceps under McG guidance and designed a randomized, crossover manikin study to test this hypothesis...
September 2017: Medicine (Baltimore)
https://www.readbyqxmd.com/read/28851399/a-mixed-methods-feasibility-and-external-pilot-study-to-inform-a-large-pragmatic-randomised-controlled-trial-of-the-effects-of-surgical-wound-dressing-strategies-on-surgical-site-infections-bluebelle-phase-b-study-protocol-for-a-randomised-controlled-trial
#18
Barnaby C Reeves, Lazaros Andronis, Jane M Blazeby, Natalie S Blencowe, Melanie Calvert, Joanna Coast, Tim Draycott, Jenny L Donovan, Rachael Gooberman-Hill, Robert J Longman, Laura Magill, Jonathan M Mathers, Thomas D Pinkney, Chris A Rogers, Leila Rooshenas, Andrew Torrance, Nicky J Welton, Mark Woodward, Kate Ashton, Katarzyna D Bera, Gemma L Clayton, Lucy A Culliford, Jo C Dumville, Daisy Elliott, Lucy Ellis, Hannah Gould-Brown, Rhiannon C Macefield, Christel McMullan, Caroline Pope, Dimitrios Siassakos, Sean Strong, Helen Talbot
BACKGROUND: Surgical site infections (SSIs) are common, occurring in up to 25% of > 4 million operations performed in England each year. Previous trials of the effect of wound dressings on the risk of developing a SSI are of poor quality and underpowered. METHODS/DESIGN: This study is a feasibility and pilot trial to examine the feasibility of a full trial that will compare simple dressings, no dressing and tissue-glue as a dressing. It is examining the overall acceptability of trial participation, identifying opportunities for refinement, testing the feasibility of and validating new outcome tools to assess SSI, wound management issues and patients' wound symptom experiences...
August 29, 2017: Trials
https://www.readbyqxmd.com/read/28843757/changing-operating-room-culture-implementation-of-a-postoperative-debrief-and-improved-safety-culture
#19
Stephen T Magill, Doris D Wang, W Caleb Rutledge, Darryl Lau, Mitchel S Berger, Sujatha Sankaran, Catherine Y Lau, Sarah G Imershein
BACKGROUND: Patient safety is foundational to neurosurgical care. Postprocedural "debrief" checklists have been proposed to improve patient safety, but data about their use in neurosurgery are limited. Here, we implemented an initiative to routinely perform postoperative debriefs and evaluated the impact of debriefing on operating room (OR) safety culture. METHODS: A 10-question safety attitude questionnaire (SAQ) was sent to neurosurgical OR staff at a major academic medical center before and 18 months after the implementation of a postoperative debriefing initiative...
November 2017: World Neurosurgery
https://www.readbyqxmd.com/read/28827271/adapting-to-ulcerative-colitis-to-try-to-live-a-normal-life-a-qualitative-study-of-patients-experiences-in-the-midlands-region-of-england
#20
Christel McMullan, Thomas D Pinkney, Laura L Jones, Laura Magill, Dmitri Nepogodiev, Shri Pathmakanthan, Rachel Cooney, Jonathan M Mathers
OBJECTIVE: To provide a framework that is able to categorise whether patients are able to adapt to and lead a 'normal' life with ulcerative colitis (UC) and to detail the factors that influence this. DESIGN: Qualitative research study using in-depth semi-structured interviews. SETTING: Four clinical sites in the West and East Midlands regions of England. PARTICIPANTS: 28 adult patients diagnosed with UC for years between 1 and 22...
August 21, 2017: BMJ Open
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