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https://www.readbyqxmd.com/read/27909119/impact-of-a-learning-curve-on-the-survivorship-of-4802-cementless-total-hip-arthroplasties
#1
P Magill, J Blaney, J C Hill, M P Bonnin, D E Beverland
AIMS: Our aim was to report survivorship data and lessons learned with the Corail/Pinnacle cementless total hip arthroplasty (THA) system. PATIENTS AND METHODS: Between August 2005 and March 2015, a total of 4802 primary cementless Corail/Pinnacle THAs were performed in 4309 patients. In March 2016, we reviewed these hips from a prospectively maintained database. RESULTS: A total of 80 hips (1.67%) have been revised which is equivalent to a cumulative risk of revision of 2...
December 2016: Bone & Joint Journal
https://www.readbyqxmd.com/read/27892796/using-a-divided-attention-stepping-accuracy-task-to-improve-balance-and-functional-outcomes-in-an-individual-with-incomplete-spinal-cord-injury-a-case-report
#2
Susan J Leach, Richard A Magill, Joyce R Maring
A spinal cord injury (SCI) frequently results in impaired balance, endurance, and strength with subsequent limitations in functional mobility and community participation. The purpose of this case report was to implement a training program for an individual with a chronic incomplete SCI using a novel divided-attention stepping accuracy task (DASAT) to determine if improvements could be made in impairments, activities, and participation. The client was a 51-year-old male with a motor incomplete C4 SCI sustained 4 years prior...
November 28, 2016: Physiotherapy Theory and Practice
https://www.readbyqxmd.com/read/27856070/impact-of-removing-mucosal-barrier-injury-laboratory-confirmed-bloodstream-infections-from-central-line-associated-bloodstream-infection-rates-in-the-national-healthcare-safety-network-2014
#3
Isaac See, Minn M Soe, Lauren Epstein, Jonathan R Edwards, Shelley S Magill, Nicola D Thompson
Central line-associated bloodstream infection (CLABSI) event data reported to the National Healthcare Safety Network from 2014, the first year of required use of the mucosal barrier injury laboratory-confirmed bloodstream infection (MBI-LCBI) definition, were analyzed to assess the impact of removing MBI-LCBI events from CLABSI rates. CLABSI rates decreased significantly in some location types after removing MBI-LCBI events, and MBI-LCBI events will be removed from publicly reported CLABSI rates.
November 14, 2016: American Journal of Infection Control
https://www.readbyqxmd.com/read/27845775/defining-the-role-of-corticotropin-releasing-factor-binding-protein-in-alcohol-consumption
#4
C L Haass-Koffler, A T Henry, G Melkus, J A Simms, M Naemmuddin, C K Nielsen, A W Lasek, M Magill, M L Schwandt, R Momenan, C A Hodgkinson, S E Bartlett, R M Swift, A Bonci, L Leggio
The corticotropin releasing factor (CRF) exerts its effects by acting on its receptors and on the binding protein (CRFBP), and has been implicated in alcohol use disorder (AUD). Therefore, identification of the exact contribution of each protein that mediates CRF effects is necessary to design effective therapeutic strategies for AUD. A series of in vitro/in vivo experiments across different species were performed to define the biological discrete role of CRFBP in AUD. First, to establish the CRFBP role in receptor signaling, we developed a novel chimeric cell-based assay and showed that CFRBP full length can stably be expressed on the plasma membrane...
November 15, 2016: Translational Psychiatry
https://www.readbyqxmd.com/read/27805495/in-memoriam-antoinette-m-gentile-1936-2016
#5
Andrew M Gordon, Lori Quinn, Terry R Kaminski, Richard A Magill
No abstract text is available yet for this article.
November 2016: Journal of Motor Behavior
https://www.readbyqxmd.com/read/27790211/modular-approach-to-select-bacteriophages-targeting-pseudomonas-aeruginosa-for-their-application-to-children-suffering-with-cystic-fibrosis
#6
REVIEW
Victor Krylov, Olga Shaburova, Elena Pleteneva, Maria Bourkaltseva, Sergey Krylov, Alla Kaplan, Elena Chesnokova, Leonid Kulakov, Damian Magill, Olga Polygach
This review discusses the potential application of bacterial viruses (phage therapy) toward the eradication of antibiotic resistant Pseudomonas aeruginosa in children with cystic fibrosis (CF). In this regard, several potential relationships between bacteria and their bacteriophages are considered. The most important aspect that must be addressed with respect to phage therapy of bacterial infections in the lungs of CF patients is in ensuring the continuity of treatment in light of the continual occurrence of resistant bacteria...
2016: Frontiers in Microbiology
https://www.readbyqxmd.com/read/27789628/implementation-of-care-management-an-analysis-of-recent-ahrq-research
#7
Andrada Tomoaia-Cotisel, Timothy W Farrell, Leif I Solberg, Carolyn A Berry, Neil S Calman, Peter F Cronholm, Katrina E Donahue, David L Driscoll, Diane Hauser, Jeanne W McAllister, Sanjeev N Mehta, Robert J Reid, Ming Tai-Seale, Christopher G Wise, Michael D Fetters, Jodi Summers Holtrop, Hector P Rodriguez, Cherie P Brunker, Erin L McGinley, Rachel L Day, Debra L Scammon, Michael I Harrison, Janice L Genevro, Robert A Gabbay, Michael K Magill
Care management (CM) is a promising team-based, patient-centered approach "designed to assist patients and their support systems in managing medical conditions more effectively." As little is known about its implementation, this article describes CM implementation and associated lessons from 12 Agency for Healthcare Research and Quality-sponsored projects. Two rounds of data collection resulted in project-specific narratives that were analyzed using an iterative approach analogous to framework analysis. Informants also participated as coauthors...
October 20, 2016: Medical Care Research and Review: MCRR
https://www.readbyqxmd.com/read/27778211/resection-of-falx-and-parasagittal-meningioma-complication-avoidance
#8
Stephen T Magill, Philip V Theodosopoulos, Michael W McDermott
Falx and parasagittal meningiomas are common locations for meningiomas of the cranial vault. Many of these tumors are now discovered incidentally during cranial imaging for other reasons. Therefore, in the calculation of the risks and benefits of surgery it behooves the surgeon to do all he/she can to avoid surgical complications. This is a heavily experience based article based off the senior author's experience with over 1200 intracranial meningiomas. We present three cases to illustrate some of the decision-making and techniques used to reduce complications in the management of these cases treated with an open operation...
October 24, 2016: Journal of Neuro-oncology
https://www.readbyqxmd.com/read/27767943/equine-assisted-occupational-therapy-increasing-engagement-for-children-with-autism-spectrum-disorder
#9
Cecilia Llambias, Joyce Magill-Evans, Veronica Smith, Sharon Warren
Engagement in meaningful activities is essential to development and is often reduced in children with autism spectrum disorder (ASD) who have limited engagement in activities or relationships. A multiple-baseline design was used with 7 children with ASD ages 4-8 yr to assess the effect of including a horse in occupational therapy intervention on task engagement. The children showed improvements in engagement. Including horses in occupational therapy sessions may be a valuable addition to conventional treatments to increase task engagement of children with ASD...
November 2016: American Journal of Occupational Therapy: Official Publication of the American Occupational Therapy Association
https://www.readbyqxmd.com/read/27761036/does-c-mac-%C3%A2-video-laryngoscope-improve-the-nasotracheal-intubating-conditions-compared-to-macintosh-direct-laryngoscope-in-paediatric-patients-posted-for-tonsillectomy-surgeries
#10
Vinuta V Patil, Bala H Subramanya, N Kiranchand, S Bala Bhaskar, Srinivasalu Dammur
BACKGROUND AND AIMS: C-MAC(®) video laryngoscope (VL) with Macintosh blade has been found to improve Cormack-Lehane (C-L) laryngoscopic view as well as intubating conditions for orotracheal intubation. However, studies done on the performance of C-MAC(®) VL for nasotracheal intubation (NTI) are very few in number. Hence, we compared laryngoscopy and intubating conditions between Macintosh direct laryngoscope and C-MAC(®) VL for NTI. METHODS: Sixty American Society of Anesthesiologists Physical Status I, II patients, aged 8-18 years, posted for tonsillectomy surgeries under general anaesthesia with NTI were randomised, into two groups...
October 2016: Indian Journal of Anaesthesia
https://www.readbyqxmd.com/read/27704820/the-synthesis-and-characterization-of-highly-fluorescent-polycyclic-azaborine-chromophores
#11
Carl Jacky Saint-Louis, Lacey L Magill, Julie A Wilson, Andrew R Schroeder, Sarah E Harrell, Nicolle S Jackson, Jamie A Trindell, Saraphina Kim, Alexander R Fisch, Lyndsay Munro, Vincent Joseph Catalano, Charles Edwin Webster, Pamela P Vaughan, Karen S Molek, Alan K Schrock, Michael T Huggins
Six new heteroaromatic polycyclic azaborine chromophores were designed, synthesized and investigated as easily tunable high-luminescent organic materials. The impact of the nitrogen-boron-hydroxy (N-BOH) unit in the azaborines was investigated by comparison with their N-carbonyl analogs. Insertion of the N-B(OH)-C unit into heteroaromatic polycyclic compounds resulted in strong visible absorption, and sharp fluorescence with efficient quantum yields. The solid-state fluorescence of the heteroaromatic polycyclic compounds displayed a large Stokes shift compare to being in solution...
October 5, 2016: Journal of Organic Chemistry
https://www.readbyqxmd.com/read/27696230/is-the-hypothalamic-pituitary-adrenal-axis-disrupted-in-type-2-diabetes-mellitus
#12
EDITORIAL
Hershel Raff, Steven B Magill
No abstract text is available yet for this article.
November 2016: Endocrine
https://www.readbyqxmd.com/read/27692185/the-alcohol-intervention-mechanisms-scale-aims-preliminary-reliability-and-validity-of-a-common-factor-observational-rating-measure
#13
M Magill, Timothy R Apodaca, Justin Walthers, Jacques Gaume, Ayla Durst, Richard Longabaugh, Robert L Stout, Kathleen M Carroll
The present work provides an overview, and pilot reliability and validity for the Alcohol Intervention Mechanisms Scale (AIMS). The AIMS measures therapist interventions that occur broadly across modalities of behavioral treatment for alcohol use disorder. It was developed based on identified commonalities in the function rather than content of therapist interventions in observed therapy sessions, as well as from existing observer rating systems. In the AIMS, the primary function areas are: explore (four behavior count codes), teach (five behavior count codes), and connect (three behavior count codes)...
November 2016: Journal of Substance Abuse Treatment
https://www.readbyqxmd.com/read/27679711/frequently-relapsing-anti-glomerular-basement-membrane-antibody-disease-with-changing-clinical-phenotype-and-antibody-characteristics-over-time
#14
Bobby Gu, Alex B Magil, Sean J Barbour
Anti-glomerular basement membrane (GBM) antibody disease is a typically monophasic autoimmune disease with severe pulmonary and renal involvement. We report an atypical case of frequently relapsing anti-GBM antibody disease with both anti-GBM antibody-positive flares with pulmonary and renal involvement, and anti-GBM antibody-negative flares that were pulmonary limited with no histologic renal disease. This is the first report of alternating disease phenotype and anti-GBM antibody status over time. Disease severity paralleled the detection of anti-GBM antibodies but was independent of IgG subtype staining along the GBM...
October 2016: Clinical Kidney Journal
https://www.readbyqxmd.com/read/27671529/the-effect-of-contouring-on-fatigue-resistance-of-three-types-of-fracture-fixation-plates
#15
Angela S P Lin, Chelsea M Fechter, Mark Magill, Felix Wipf, Thomas Moore, Robert E Guldberg
BACKGROUND: Metallic reconstruction plates used for fracture stabilization typically require intraoperative contouring for patient-specific anatomical fit. Despite this, characterization of plate mechanical properties after contouring has previously been limited. The objective of this study was to assess whether contouring affects fatigue resistance for three types of Stryker seven-hole stainless steel (SS) 316LVM fracture fixation plates. The hypothesis was that for each plate type, more contouring repetitions would result in lower fatigue resistance...
September 26, 2016: Journal of Orthopaedic Surgery and Research
https://www.readbyqxmd.com/read/27669410/secretagogin-expression-delineates-functionally-specialized-populations-of-striatal-parvalbumin-containing-interneurons
#16
Farid N Garas, Rahul S Shah, Eszter Kormann, Natalie M Doig, Federica Vinciati, Kouichi C Nakamura, Matthijs C Dorst, Yoland Smith, Peter J Magill, Andrew Sharott
Corticostriatal afferents can engage parvalbumin-expressing (PV+) interneurons to rapidly curtail the activity of striatal projection neurons (SPNs), thus shaping striatal output. Schemes of basal ganglia circuit dynamics generally consider striatal PV+ interneurons to be homogenous, despite considerable heterogeneity in both form and function. We demonstrate that the selective co-expression of another calcium-binding protein, secretagogin (Scgn), separates PV+ interneurons in rat and primate striatum into two topographically-, physiologically- and structurally-distinct cell populations...
2016: ELife
https://www.readbyqxmd.com/read/27624915/expression-and-prognostic-impact-of-immune-modulatory-molecule-pd-l1-in-meningioma
#17
Seunggu J Han, Gerald Reis, Gary Kohanbash, Shruti Shrivastav, Stephen T Magill, Annette M Molinaro, Michael W McDermott, Philip V Theodosopoulos, Manish K Aghi, Mitchel S Berger, Nicholas A Butowski, Igor Barani, Joanna J Phillips, Arie Perry, Hideho Okada
While immunotherapy may offer promising new approaches for high grade meningiomas, little is currently known of the immune landscape in meningiomas. We sought to characterize the immune microenvironment and a potentially targetable antigen mesothelin across WHO grade I-III cases of meningiomas, and how infiltrating immune populations relate to patient outcomes. Immunohistochemistry was performed on tissue microarrays constructed from 96 meningioma cases. The cohort included 16 WHO grade I, 62 WHO grade II, and 18 WHO grade III tumors...
September 13, 2016: Journal of Neuro-oncology
https://www.readbyqxmd.com/read/27621168/stepping-through-the-transition-from-department-chair
#18
Steven Zweig, Chris Matson, Mike Magill, Tom Campbell, Ardis Davis
No abstract text is available yet for this article.
September 2016: Annals of Family Medicine
https://www.readbyqxmd.com/read/27621155/time-to-do-the-right-thing-end-fee-for-service-for-primary-care
#19
EDITORIAL
Michael K Magill
No abstract text is available yet for this article.
September 2016: Annals of Family Medicine
https://www.readbyqxmd.com/read/27565832/a-randomized-controlled-trial-of-culturally-adapted-motivational-interviewing-for-hispanic-heavy-drinkers-theory-of-adaptation-and-study-protocol
#20
Christina S Lee, Suzanne M Colby, Molly Magill, Joanna Almeida, Tonya Tavares, Damaris J Rohsenow
BACKGROUND: The NIH Strategic Plan prioritizes health disparities research for socially disadvantaged Hispanics, to reduce the disproportionate burden of alcohol-related negative consequences compared to other racial/ethnic groups. Cultural adaptation of evidence-based treatments, such as motivational interviewing (MI), can improve access and response to alcohol treatment. However, the lack of rigorous clinical trials designed to test the efficacy and theoretical underpinnings of cultural adaptation has made proof of concept difficult...
September 2016: Contemporary Clinical Trials
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