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Hiroko Fujisato, Masaya Ito, Yoshitake Takebayashi, Hiroki Hosogoshi, Noriko Kato, Shun Nakajima, Mitsuhiro Miyamae, Yuki Oe, Satoshi Usami, Ayako Kanie, Masaru Horikoshi, Matthias Berking
BACKGROUND: The Emotion Regulation Skills Questionnaire (ERSQ) comprehensively assesses nine aspects of emotion regulation skills: awareness, clarity, sensation, understanding, compassionate self-support, modification, acceptance, tolerance, and readiness to confront. However, it is unknown about the levels of emotion regulation skills in various mental disorders, and its cross-cultural validity. We developed a Japanese version of the ERSQ, then examined its validity and reliability in clinical and non-clinical populations...
October 11, 2016: Journal of Affective Disorders
Irfan Sahin, Baris Gungor, Berk Ozkaynak, Fatih Uzun, Suat Hayri Küçük, Ilhan Iker Avci, Ender Ozal, Burak Ayça, Sukru Cetın, Ertugrul Okuyan, Mustafa Hakan Dinckal
BACKGROUND: Correlation of increased copeptin levels with various cardiovascular diseases has been described. The clinical use of copeptin levels in patients with hypertrophic cardiomyopathy (HCM) has not been investigated before. HYPOTHESIS: In this study, we aimed to investigate the prognostic value of copeptin levels in patients with hypertrophic cardiomyopathy (HCM). METHODS: HCM was defined as presence of left ventricular wall thickness ≥15 mm in a subject without any concomitant disease that may cause left ventricular hypertrophy...
October 21, 2016: Clinical Cardiology
Gergő Orbán, Pietro Berkes, József Fiser, Máté Lengyel
Neural responses in the visual cortex are variable, and there is now an abundance of data characterizing how the magnitude and structure of this variability depends on the stimulus. Current theories of cortical computation fail to account for these data; they either ignore variability altogether or only model its unstructured Poisson-like aspects. We develop a theory in which the cortex performs probabilistic inference such that population activity patterns represent statistical samples from the inferred probability distribution...
October 19, 2016: Neuron
Lotte Berk, Martin van Boxtel, Sebastian Köhler, Jim van Os
OBJECTIVE: In cross-sectional studies, positive affect (PA) has been associated with higher levels of cognitive functioning. This study examined whether positive affect (PA) is associated with change in cognitive function over 12 years in an adult population sample. METHODS: Participants (n = 258), aged 40 to 82 years, were drawn from a subsample of the Maastricht Aging Study (MAAS) and assessed at baseline, 6 years and 12 years. PA was measured at baseline with a Dutch translation of the Positive and Negative Affect Schedule (PANAS)...
October 17, 2016: International Journal of Geriatric Psychiatry
Zekiye Hasbek, Ömer Tamer Doğan, İsmail Sarı, Birsen Yücel, Mehmet Metin Şeker, Bülent Turgut, Serdar Berk, Yavuz Siliğ
OBJECTIVE: Mutations in the p53 gene are the most commonly observed genetic abnormalities in malignancies. The purpose of this study was to assess the diagnostic value of serum anti-p53 antibody (Ab) along with the correlation between serum anti-p53 Ab level and quantitative positron emission tomography (PET) parameters such as maximum standardized uptake value (SUVmax), SUVave, metabolic tumor volume, total lesion glycolysis (TLG) and tumor size. METHODS: Serum anti-p53 Ab level was studied in three groups...
October 5, 2016: Molecular Imaging and Radionuclide Therapy
Alice Diedrich, Julian Burger, Mareike Kirchner, Matthias Berking
OBJECTIVES: To identify the mechanisms involved in the association between self-compassion and depression, we examined whether adaptive emotion regulation would mediate the relationship between self-compassion and depression in individuals with unipolar depression. Furthermore, we explored which specific emotion regulation skills would be most important in this relationship. DESIGN AND METHOD: Sixty-nine individuals with unipolar depression were assessed with the Self-Compassion Scale and the Emotion Regulation Skills Questionnaire at baseline and with the Beck Depression Inventory-II 1 week later...
October 15, 2016: Psychology and Psychotherapy
Christine H Oedegaard, Lesley Berk, Michael Berk, Eric A Youngstrom, Steven C Dilsaver, Robert H Belmaker, Ketil J Oedegaard, Ole B Fasmer, Ingunn M Engebretsen
OBJECTIVE: Clinical management of bipolar disorder patients might be affected by culture and is further dependent on the context of healthcare delivery. There is a need to understand how healthcare best can be delivered in various systems and cultures. The objective of this qualitative study was to gain knowledge about culture-specific values, beliefs and practices in the medical care provided to patients with bipolar disorders from a provider perspective in various areas of the world...
October 14, 2016: Australian and New Zealand Journal of Psychiatry
Michael T Jarratt, Terry M Jones, Joan-En Chang-Lin, Warren Tong, David R Berk, Vince Lin, Alexandre Kaoukhov
BACKGROUND: Reducing the dosing frequency of topical acne treatments to once daily may improve adherence. OBJECTIVE: Evaluate pharmacokinetics (PK), safety, and tolerability of 3 formulations of once-daily dapsone gel, 7.5% and of twice-daily dapsone gel, 5% over 28 days in patients with moderate acne vulgaris. METHODS: This phase 1, multicenter, parallel-group study randomized males and females aged 16 to 35 years to 1 of 3 dapsone gel, 7...
October 1, 2016: Journal of Drugs in Dermatology: JDD
Tianyi He, Ruxing Zhao, Yiran Lu, Wenjuan Li, Xinguo Hou, Yu Sun, Ming Dong, Li Chen
Purpose. To investigate the effects of Corbrin Capsule (CS-C-Q80), a drug derived from Cordyceps sinensis (Berk.) Sacc., on autoimmune thyroid diseases (AITD). Methods. 44 Patients with Graves's disease (GD) and 56 patients with Hashimoto's thyroiditis (HT) were randomly assigned to treatment group (GD-Tx and HT-Tx) or control group (GD-Ct and HT-Ct). The control groups were given methimazole or levothyroxine only while the treatment groups were given Corbrin Capsule (2.0 g tid) besides the same conventional prescriptions as control groups...
2016: Evidence-based Complementary and Alternative Medicine: ECAM
C Berking, R-M Szeimies
No abstract text is available yet for this article.
October 6, 2016: Der Hautarzt; Zeitschrift Für Dermatologie, Venerologie, und Verwandte Gebiete
Markus V Heppt, Cecilia Dietrich, Saskia A Graf, Thomas Ruzicka, Julia K Tietze, Carola Berking
Melanoma is a common type of skin cancer with a high propensity to metastasize. Tyrosine kinase inhibitors targeting the mitogen-activated protein kinase (MAPK) pathway and immune checkpoint blockade have recently revolutionized the management of unresectable and metastatic disease. However, acquired resistance and primary non-response to therapy require novel treatment strategies and combinations. The purpose of this review is to provide a brief and up-to-date overview on the clinical management and current trial landscape in melanoma...
2016: Oncology Research and Treatment
Heidi R Schoen, Brent M Peyton, W Berk Knighton
A novel analytical system was developed to rapidly and accurately quantify total volatile organic compound (VOC) production from microbial reactor systems using a platinum catalyst and a sensitive CO2 detector. This system allows nearly instantaneous determination of total VOC production by utilizing a platinum catalyst to completely and quantitatively oxidize headspace VOCs to CO2 in coordination with a CO2 detector. Measurement of respiratory CO2 by bypassing the catalyst allowed the total VOC content to be determined from the difference in the two signals...
December 2016: AMB Express
Moritz Scherer, Jonas Cordes, Alexander Younsi, Yasemin-Aylin Sahin, Michael Götz, Markus Möhlenbruch, Christian Stock, Julian Bösel, Andreas Unterberg, Klaus Maier-Hein, Berk Orakcioglu
BACKGROUND AND PURPOSE: ABC/2 is still widely accepted for volume estimations in spontaneous intracerebral hemorrhage (ICH) despite known limitations, which potentially accounts for controversial outcome-study results. The aim of this study was to establish and validate an automatic segmentation algorithm, allowing for quick and accurate quantification of ICH. METHODS: A segmentation algorithm implementing first- and second-order statistics, texture, and threshold features was trained on manual segmentations with a random-forest methodology...
October 4, 2016: Stroke; a Journal of Cerebral Circulation
Kirsten A Berk, Ranitha Vongpromek, Meizi Jiang, Wolfgang J Schneider, Reinier Timman, Adrie J M Verhoeven, Hideaki Bujo, Eric J G Sijbrands, Monique T Mulder
BACKGROUND AND AIMS: Cardiovascular disease (CVD) is a major complication in patients with type 2 diabetes (T2D), especially in those with obesity. Plasma soluble low density lipoprotein receptor-relative with 11 ligand-binding repeats (sLR11) plays a role in the development of atherosclerosis and has been linked to the metabolism of triglyceride-rich lipoproteins, adiposity, and vascular complications in T2D. We aimed to determine the effect of diet-induced weight loss on plasma sLR11 levels in overweight and obese individuals with T2D...
September 22, 2016: Atherosclerosis
André F Carvalho, Michael Berk, Michael Maes
No abstract text is available yet for this article.
September 29, 2016: Current Pharmaceutical Design
Peter I Bonta, Harm J Bogaard, Inge van den Berk, Hans W M Niessen, Allard van der Wal, Petr Symersky
No abstract text is available yet for this article.
September 28, 2016: Thorax
Mark de Boer, Guido van den Berk, Natasja van Holten, Josephine Oryszczyn, Willemien Dorama, Daoud Ait Moha, Kees Brinkman
OBJECTIVE: Dolutegravir (DGV) is one of the preferred antiretroviral agents in first line cART. Though considered a well-tolerated drug, we aimed to determine the actual rate, timing, and detailed motivation of stopping DGV in a real life clinical setting. DESIGN: a cohort study including all patients that started DGV in two HIV treatment centers in the Netherlands. METHODS: All cART-naïve and cART-experienced patients who had started DGV were identified from the institutional HIV-databases...
September 24, 2016: AIDS
L B Berk, N A Mason, S Jacobs
No abstract text is available yet for this article.
October 1, 2016: International Journal of Radiation Oncology, Biology, Physics
Yasin Demir, Ümüt Güzelküçük, Serdar S Kesikburun, Berke Aras, Mehmet A Taşkaynatan
No abstract text is available yet for this article.
September 2016: PM & R: the Journal of Injury, Function, and Rehabilitation
Dincer Aydin, Mehmet Ali Sendur, Umut Kefeli, Olcun Umit Unal, Didem Tastekin, Murat Akyol, Eda Tanrikulu, Aydin Ciltas, Basak Bala Ustaalioglu, Mukremin Uysal, Onur Esbag, Dogan Yazilitas, Ozgur Tanrıverdi, Ahmet Bilici, Erkan Arpaci, Veli Berk, Tarkan Yetisyigit, Nuriye Yildirim Ozdemir, Ilhan Oztop, Ahmet Alacacioglu, Ozhan Aydin, Melike Ozcelik, Emre Yildirim, Nur Dinc, Mahmut Gumus
BACKGROUND: Small bowel adenocarcinoma (SBA) is a rare tumor of the gastrointestinal system with poor prognosis. Because these are rarely encountered tumors, the aim of this multicenter study was evaluation of prognostic factors and adjuvant chemotherapy in patients with curatively resected SBA. MATERIALS AND METHODS: A total of 78 patients diagnosed with curatively resected SBA were involved in the retrospective study. Forty-eight patients received 1 of 3 different chemotherapy regimens, whereas 30 patients did not receive any adjuvant treatment...
August 30, 2016: Clinical Colorectal Cancer
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